Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.

Abstract: A method of providing an anti-microbial coating on an object, comprises the steps of pretreating the object in a first oxygen plasma to graft oxygen-based functional groups on the surface of the object by plasma enhanced chemical vapour deposition, coating the pretreated object with a suspension of particulate graphene oxide to provide a graphene oxide coating on the object, treating the object in a hydrocarbon plasma to deposit an amorphous hydrocarbon film on the graphene oxide coating by plasma enhanced chemical vapour deposition, and treating the object in a second oxygen plasma configured to etch and flatten the coatings on the surface of the object. A prosthetic implant having a metal or metal alloy surface and an anti-microbial coating on all or part of the surface is also described.

Abstract: A method includes covering or contacting a portion of a recurrent laryngeal nerve of a subject with a shield including extraembryonic tissue. The covering occurs during a neck or reconstructive surgery of the subject.

Abstract: The invention disclosed herein generally relates to methods and systems for growing, expanding and/or obtaining 3-dimensional lung-like epithelium comprising cells having SOX9 protein activity and SOX2+ protein activity. In particular, the invention disclosed herein relates to methods and systems for growing human cells having SOX9 protein activity and SOX2+ protein activity in vitro, and for promoting pluripotent stem cell derived ventral-anterior foregut spheroid tissue into 3-dimensional lung-like epithelium comprising cells having SOX9 protein activity and SOX2+ protein activity.

Abstract: The present invention relates generally to the field of bone graft substitutes and methods for making the same, particularly the invention relates to bone graft substitutes for use in dental or orthopaedic implants. The bone graft substitutes described herein comprise a silicate based material. The silicate based material is a silicate network with a porous structure. The silicate network has one or more metal cations incorporated therein. Preferably a phosphate is also incorporated into the silicate network. The bone graft substitute may have a low density, preferably a density of less than 1.1 g/cm3. The bone graft substitute may be an aerogel or a cryogel.

Abstract: A textile graft includes a tubular wall disposed between a first open end and an opposed second open end and having an inner surface and an opposed outer surface. The tubular wall includes a textile construction of one or more filaments or yarns, the textile construction by itself being permeable to liquid. A portion of the inner surface of the tubular wall includes a coating of a substantially water-soluble material thereon. The outer surface includes a coating of a substantially water-insoluble elastomeric sealant disposed thereon. The tubular wall having the coating of the substantially water-insoluble elastomeric sealant is, after curing thereof, substantially impermeable to liquid.

Abstract: Polymer devices are disclosed with microstructured surfaces that modify their absorption pathway. Polymers which generally degrade in water by fracturing into high surface energy fragments, are modified to degrade in vivo without the formation of sharp fragments. Devices are disclosed that possess improved handling characteristics and degrade in an aqueous environment in a uniform and continuous way that favors the formation of soluble monomers rather than solid particulate. Absorbable medical implants with the disclosed surface modifications are more biocompatible, with reduced foreign body response, and dissolution into metabolizable molecular species.

Abstract: A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.

Abstract: The invention relates to a method for lubricating a component consisting of a hydrophilic compound crosslinked by means of a water-soluble transition metal chelate.

Abstract: A fragrance delivery system comprising at least one cartridge containing solid elements loaded by adsorption of an olfactory composition and opened by a grid having holes, the cross-section of which is smaller than the cross-section of the solid elements, wherein the solid elements are made of a polymer ensuring a natural delivery of the fragrances for a period of 6 to 18 months, and in that the cartridge is mounted on a cartridge holder holding the cartridge and connected to a mounting base on a fixed portion by an unstable linkage capable of ensuring an oscillating movement of the cartridge holder around a reference position.

Abstract: Various fragrance dispensers are disclosed. The fragrance dispenser can include a core unit that has a connection unit and a control unit. The fragrance dispenser can include a cartridge that is configured to engage with the core unit. The cartridge can include an impeller and a fragrant material. The fragrance dispenser can have a motor that drives the impeller, thereby dispersing the fragrance. The cartridge can be configured to disengage from the connection unit, such as when the cartridge reaches a depleted state.

Abstract: An air treatment unit having a frame and a source of UV light, with the frame having an air guidance assembly. Air within a primary treatment volume is guided by the frame to move radially outwardly from the primary treatment volume through a dispersion angle. Air within the primary treatment volume is exposed to UV light rays from the UV light source. The air treatment unit is changeable between: a) a first state wherein a predetermined part of a volume of space within which the air treatment unit resides is strategically blocked from direct exposure to UV light rays generated by the UV light source; and b) a second state wherein at least a portion of the predetermined part of the volume of space is directly exposed to UV light rays from the UV light source.

Abstract: The invention relates to a display apparatus for a domestic appliance, at least one air treatment apparatus being integrated in the display apparatus, the at least one air treatment apparatus comprising a first radiation source device by means of which a fluid, in particular air, passing through a passage channel can be treated.

Abstract: Systems and methods for creating a germicidal partition. A germicidal partition system including at least one negative ion generator including at least one negative high-voltage source, at least one high-voltage conductor electrically connected to the at least one negative high-voltage source, and at least one anode electrically connected to the at least one high-voltage conductor, and at least one fan configured to draw air into the system, direct the air through the at least one negative ion generator, and output the air through at least one manifold, wherein the air outputted through the at least one manifold is configured to create a barrier between a first air mass and a second air mass, such that the outputted air reduces at least one of the transfer of contaminants or the concentration of viable contagions between the first air mass and the second air mass.

Abstract: A supplementary device configured to be attached to a drug delivery device, the supplementary device including: first means being adapted to mechanically couple the supplementary device to a dosage selector of the drug delivery device; second means being adapted to select a dosage to be delivered by the drug delivery device; third means being adapted to mechanically couple the second means to the first means such that a dosage selection made with the second means generates a torque being transferred via the third means to the first means; a sensor configured to output signals indicative of the generated torque; and electronics configured to receive the signals output from the sensor and to determine based on the signals the selected dosage.

Abstract: A method and apparatus for a medical airway passage device suitable for maintaining an airway for a patient is provided. The medical airway passage device includes a novel coupler device designed to prevent contamination, infection, and unwanted discharge of patient fluids and solids during usage. The coupler includes a locking mechanism configured to lock the coupler to a breathing tube and thus preventing unintentional decoupling of the coupler from the breathing tube. The coupler also includes a self-sealing suction port for removing patient discharges. The coupler further includes a filter for enabling the free flowing passage of airflow but prevention of the flow of patient discharges.

Abstract: Ventilation masks are described herein. A ventilation mask includes a mask body and a gas manifold. The mask body defines a patient cavity and further includes a patient opening in fluid communication with the patient cavity; and at least one vent opening formed through the mask body, the at least one vent opening in fluid communication with the patient cavity, wherein the at least one vent opening is disposed generally opposite to the patient opening. The gas manifold is coupled to the mask body. The gas manifold can define a gas channel. The gas manifold can include a plurality of vectored gas ports in fluid communication with the gas channel, wherein the plurality of vectored gas ports are configured to create a curtain effect gas flow within the patient cavity to form a gas curtain within the patient cavity and adjacent to the at least one vent opening.

Abstract: A method for setting a control device or a closed-loop control device of a blood treatment apparatus, includes providing, determining or reading out a correction factor and correcting the flow value and/or the treatment target entered by the user by or about the correction factor. Furthermore, the present disclosure relates to a blood treatment apparatus, a digital storage medium, a computer program product, and a computer program.

Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.

Abstract: An automated peritoneal dialysis system and machine configured to perform dextrose mixing are disclosed. An example dialysis machine includes a pump, a first solution having a first formulation stored in a first container that is placed in fluid communication with the pump, and a second solution having a second formulation stored in a second container that is also placed in fluid communication with the pump. The first container has a first unique identifier indicative of the first formulation and the second container has a second unique identifier indicative of the second formulation. The dialysis machine also includes a logic implementer programmed to receive a therapy prescription and operate the pump if the first formulation indicated by the first unique identifier is specified by the therapy prescription, or the second formulation indicated by the second unique identifier is specified by the therapy prescription.

Abstract: Described is a method for controlling fluid volume balance. A controller is configured with a first set of inputs comprising a hematocrit, a total blood volume, and an ACD ratio. A maximum extracorporeal RBC amount during the procedure is estimated based on the first set of inputs. A fluid circuit is primed with a priming fluid. Whole blood is drawn from a blood source and separated into a RBC component, a target cell component, and a plasma component. The target cell component is directed to a product container. The product container comprising the target cell component is treated. A treated target cell component, a portion of the RBC component remaining in the fluid circuit, and/or a portion of the plasma component remaining in the fluid circuit are returned to the blood source. A first response action is provided if the maximum extracorporeal RBC amount estimated is above a programmed limit.

Abstract: An extracorporeal blood treatment apparatus comprises: a blood treatment device; an extracorporeal blood circuit comprising a blood withdrawal line and a blood return line coupled to the extracorporeal blood treatment device, wherein the blood return line presents a heating zone coupled or configured to be coupled to a blood warmer; a blood pump configured to be coupled to a pump section of the blood withdrawal line; at least a post-infusion line connected to the blood return line upstream of the heating zone; an air trapping device placed on the blood return line upstream of the heating zone.

Abstract: An automatic urine treatment system according to an embodiment of the present invention includes a receiver for receiving wearer's excrement; a main body including a urine tank for receiving and storing urine from the receiver, and a vacuum pump for sucking air into the urine tank and transferring a negative pressure to the receiver; and a first connecting hose connecting the receiver and the urine tank. A strip accommodation unit for accommodating a strip for analyzing components of the stored urine through color change is formed inside the urine tank, and on the outer surface of the urine tank, urine analysis is performed using a first optical sensor unit for sensing color change of the strip, and a second optical sensor unit for sensing at least one among turbidity and color change of the stored urine. There is an advantage of being able to confirm the health condition of disabled or elderly people in real-time through the urine information analyzed in this way.

Abstract: A cartridge for use in an aerosol-generating system, the cartridge comprising: a first compartment having a first air inlet and a first air outlet, the first compartment containing a nicotine source; and a second compartment having a second air inlet and a second air outlet, the second compartment containing an acid source; wherein the first compartment comprises a first air flow channel extending from the first air inlet, or the first air outlet, longitudinally along at least a portion of the first compartment, wherein the first air flow channel is adjacent to and in fluid communication with the nicotine source; or wherein the second compartment comprises a second air flow channel extending from the second air inlet, or the second air outlet, longitudinally along at least a portion of the second compartment, wherein the second air flow channel is adjacent to and in fluid communication with the acid source; or wherein the first compartment comprises a first air flow channel extending from the first air inlet,

Abstract: On-demand, hand-held vaporizer that operates primarily by convection. The vaporizer is configured to permit very rapid (e.g., within a few seconds) heating of air drawn through an oven chamber to a predetermined or selectable vaporizing temperature to vaporize a material (e.g., loose leaf plant material, etc.) that is held in the oven chamber. The vaporizer provides efficient transfer of air being heated as well as rapid delivery of vaporizable material to a user.

Abstract: In one embodiment, a filter assembly for use in an insufflation system is described. The filter assembly comprises: a filter medium operative to filter medical gases; a housing comprising an inlet, an outlet and the filter medium, the housing defining a gases flow path through the filter medium between the inlet and the outlet; and at least one heating element being positioned in the housing and being configured to heat the filter medium; and wherein, the at least one heating element is spaced apart from the filter medium and from an inner surface of the housing.

Abstract: Systems and methods are described for monitoring usage of a medicament dispenser—particularly an inhaled medicament dispenser. The usage monitoring device is configured to emit a detection signal responsive to receiving a request to locate the medicament dispenser. The detection signal alerts presence of the medicament dispenser to the user of the medicament dispenser. The usage monitoring device can be embodied as an attachment configured to be selectively coupled to one of a variety of different inhalers including, for example, a Diskus-type inhaler and a Respimat-type inhaler.

Abstract: A component of an electronic vapor provision device with a reservoir for storing source liquid, an atomizer for vaporizing source liquid from the reservoir and delivering vapor into an air flow path through the device, and an electrical power supply for providing electrical power to the atomizer comprises an absorbent element to collect source liquid escaped from the reservoir and located so as to be upstream of the atomizer with respect to an air flow direction along the air flow path when the component is assembled into the electronic vapor provision device.

Abstract: A vaporizing assembly for an aerosol generating system includes a sheet heating element and a delivery device configured to deliver a liquid aerosol-forming substrate from a liquid storing portion to the sheet heating element. The sheet heating element is spaced apart from the delivery device and is configured to heat the delivered liquid aerosol forming substrate.

Abstract: Devices and methods for delivering air to a patient are provided. A device includes a first portion having a first airflow inlet and a sensor configured to sense airflow, the first portion defining a first airflow path, and a second portion comprising a second airflow inlet, an impeller, and an outlet for communicating airflow to a patient, the second portion defining a second airflow path. The device includes means for coupling the first portion and the second portion, such that the sensor sensing airflow in the first portion causes corresponding movement of the impeller, wherein the impeller is configured to impel air through the second airflow inlet and out of the outlet to the patient, upon movement of the impeller.

Abstract: A CPAP apparatus according to the present disclosure includes a housing, a hose whose one end communicates with a connection portion, a fan configured to expel air flowing in from an intake port, from another end of the hose, a motor and a motor driving unit configured to rotationally drive the fan, a control unit configured to control the motor driving unit, and a flow rate sensor. The control unit includes a command generation unit configured to generate a command value of a rotation number of the fan such that a pressure to be expelled from the other end of the hose becomes a target pressure, and a command correction unit configured to correct the command value based on a flow rate value obtained by the flow rate sensor.

Abstract: A patient ventilating (23) and aspirating system (8) is disclosed that has a suction tube (9) and connector (6) for connecting to a catheter mount that has a sealed passageway (15) The catheter mount passageway (15) is sealed with an elastomeric seal (16) including a perforation or slit (17). A connector (12) with a piercing member is associated with the suction tube (9). When the connector is attached to the catheter mount the piercing member (20) pierces the seal (16) such that the suction tube (9) can pass through the connector (6) and catheter mount.

Abstract: Apparatus and methods automate selection of patient interface(s) according to their size, such as with processing in a processor(s) or in a server(s). Image data captured by an image sensor may be received. The captured image data may contain facial feature(s) of an intended user of the patient interface. The facial features may be captured in association with a predetermined reference feature of known dimension(s). The user's facial feature(s) and the reference feature may be detected in the captured image data. Image pixel data of the image may be processed to measure an aspect of the detected facial feature(s) based on the reference feature. A patient interface size may be detected from standard patient interface sizes based on a comparison between the measured aspect of the facial feature(s) and a data record relating sizing information of the standard patient interface sizes and the measured aspect of the facial feature(s).

Abstract: A patient interface device is includes a cushion and a frame assembly coupled to the cushion, the frame assembly including a main frame member and a stiffening structure coupled to the main frame member, the stiffening structure having a main arm, a first Y-portion coupled to a first end of the main arm having first and second front branches extending at upward and downward angles, respectively, from the first end of the main arm, and a second Y-portion coupled to a second end of the main arm having first and second rear branches extending at upward and downward angles, respectively, from the second end of the main arm.

Abstract: Condensation traps are disclosed herein for the purpose of trapping and removing water condensed from the humidified air present within respiratory ventilatory systems and tubing. Traps disclosed herein can be positioned inline with the tubing, and therefore allow the trap to be positioned very near the patient interface, and minimize dead space between the trap and the patient interface. Minimizing the dead space in this manner prevents water from condensing prior to entering the trap. Respiratory ventilator systems incorporating condensation traps and methods of mechanical ventilation relying on condensation traps are also disclosed herein.

Abstract: A blower unit for use as part of an integrated blower/humidification system is described. The blower unit has an outer casing, which encloses and forms part of the blower unit, the casing including an air inlet vent. The blower unit further includes a humidifier compartment for receiving a humidifier unit with a separate gases inlet and outlet, the compartment having a heater base for heating the contents of the humidifier unit. The compartment also has a blower inlet port which aligns with the humidifier unit inlet in use, the blower providing a gases path through the casing between the inlet vent and the inlet port. The blower unit also includes a fan for providing a pressurised gases stream along the gases path, and a power supply unit for powering the fan. The gases path is routed over the power supply unit in order to provide a cooling air flow.

Abstract: An eyeshade and an electroencephalogram detection system are provided. The eyeshade includes an eyeshade main body; and an electroencephalogram acquisition unit, a controller and a heating unit which are disposed on the eyeshade main body. The electroencephalogram acquisition unit is configured to acquire a brain electrical signal of a wearer. The controller includes a converter and is configured to receive the brain electrical signal from the electroencephalogram acquisition unit, the converter is detachably coupled to the electroencephalogram acquisition unit and is configured to convert the brain electrical signal into a communication signal and transmit the communication signal to outside when coupled to the electroencephalogram acquisition unit. The heating unit is configured to heat an eye region of the wearer.

Abstract: Various embodiments relate to the field of communications technologies, and provide a light adjustment method and a terminal to resolve a problem that an existing light therapy device cannot flexibly adjust light based on a light requirement of a user and cannot more intelligently adjust a circadian rhythm of the user. In those embodiments, an awake time period and a sleep time period of a user is determined by the terminal, and parameter thresholds in the awake time period and the sleep time period is determined by the terminal. In those embodiments, a light parameter in a current time period is obtain by the terminal, and based on the light parameter in the current time period, a light parameter of light emitted by a light source device is then adjusted by the terminal.

Abstract: Embodiments include a lighting device that includes a first illumination source comprising a light-emitting diode (LED) of a first color that generates a first light output with a first melanopic ratio of greater than 0.8, and a second illumination source comprising an LED of a second color that generates a second light output with a second melanopic ratio that is less than the first melanopic ratio. The lighting device also includes a light distribution unit for directing and distributing illumination generated by the first and second illumination sources, where at least one of the first illumination source and the second illumination source is affixed to the light distribution unit, and where the first and second illumination sources are oriented relative to one another such that their respective light outputs are directed in different directions.

Abstract: A method and apparatus for stimulating neural activity in the brain of a user of an apparatus with a display screen by causing at least one portion of the display screen to flicker in a controlled manner and utilizing the apparatus to measure an effect on a user exposed to the flicker for a time.

Abstract: A method to manage flushing of a catheter assembly may include providing a clamp for a fluid tube configured to be coupled to the catheter assembly. The clamp may include a sensor configured to detect the clamp is closed. The method may include starting a timer in response to the sensor detecting the clamp is closed. The method may include providing an alert in response to the timer reaching a predetermined duration of time. The alert may indicate to a clinician that the catheter assembly should be opened and flushed, which may prevent occlusion of the catheter assembly.

Abstract: Systems and methods of manufacturing 3D printed medical devices. The method includes feeding a first filament and a second filament into an interior cavity of a heating cartridge and melting each of the filaments on a substrate. The heating cartridge is then moved linearly and rotationally relative to the substrate to form a jacket including material from each of the first and second filaments. Further, rotating the substrate provides a uniform mixture and creates support rings between the filament materials within the structure of the jacket.

Abstract: A modular medical device catheter system comprises a parent module and an adapter module. The adapter module is configured to engage an inner lumen of a distal end of the parent module to couple the adapter module with the parent module.

Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.

Abstract: A stabilized coronary sinus catheter system having a proximal section and a distal section with a memory shape portion, and a tip, distal of the memory shape portion. A handle having a body, a tip deflection actuator, a memory shape portion deployment actuator, and an axis. The tip is in line with the axis and the tip deflection actuator is at a first position. The tip is deflected out of alignment with the axis when the tip deflection actuator is at a second position. A third position is a delivery configuration where the memory shape portion and the tip are in line with the axis. The memory shape portion deployment actuator is at a first location. A deployed configuration allows the memory shape portion to form a predetermined shape conforming to the shape of the coronary sinus when the memory shape portion deployment actuator is at a second location.

Abstract: A catheter for dialysis for long-term application features a proximal end for introducing into a blood vessel, a distal end for extracting blood and for introducing purified blood, and a fixing member surrounding a tube section for fixing the catheter on the patient. The fixing member has a receiving part and an opening part, wherein, with respect to the receiving part, the opening part can be moved from an opening position, in which the tube section is insertable into the fixing member, into a closing position, in which the tube section is fixed in the fixing member.

Abstract: A medical device may include an introducer sheath, having a distal and a proximal end and a lumen extending from the distal end to the proximal end. The introducer sheath may also include a tab formed at the distal end and extending distal to the lumen, and a frangible portion extending between the distal end and the proximal end.

Abstract: A looped wire is provided for placing an endograft into a blood vessel. The looped wire comprising a flexible guidewire with one or more loops distributed along its length. The one or more loops have an inner diameter that is larger than the thickness of a suture or wire for threading the suture or wire through. The one or more loops is adapted for sliding along the suture or wire. Endograft system comprising the looped wire, and methods of using the looped wire are also provided.

Abstract: The present application relates to a balloon catheter, which is a rapid exchange structure and has a balloon catheter body and a hub, wherein the balloon catheter body has a push member, a transition member, a balloon loading member, a balloon, a imaging mark and a tip head, the balloon loading member comprises an outer tube and an inner tube, a distal end of the handle is connected with a proximal end of the push member, a proximal end of the transition member extends from a distal end of the push member, a distal end of the transition member is nested inside a proximal end of the outer tube of the balloon loading member, the balloon loading member loads the balloon, the tip head is provided on a distal end of the balloon, the imaging mark is provided on the balloon loading member, characterized in that the balloon has a wall thickness of 10-15 microns, the balloon has a nominal dilation pressure of 3-4 atm, and the balloon catheter has a rated burst pressure of is 10-12 atm.

Abstract: A device including a sheath for insertion through an arteriotomy of a patient. The sheath comprises a tubular sheath body having a longitudinal axis, an open proximal end, an open distal end, an outer surface and an inner surface, the inner surface defining a lumen between the proximal and distal ends for passage of a catheter device. The sheath also comprises an inflatable balloon disposed within the lumen. The inflatable balloon is configured to occupy a longitudinal space in the lumen between the inner surface of the sheath body and the catheter device when the catheter device is disposed within the sheath and the inflatable balloon is inflated, and fluidically seal the lumen.