Patents Issued in January 9, 2024
  • Patent number: 11865217
    Abstract: The present invention relates to transdermal delivery systems, methods and kits that include an agent to penetrate the basement membrane, a membrane of the skin previously known to be difficult to penetrate. In particular, the formulation includes a basement membrane disruptor that reversibly denatures the basement membrane of the skin. The formulation of the present invention further includes having at least one penetration agent, at least one vaso-modulator, and at least one active ingredient. In an embodiment, the penetration agent includes a solvent, a lipophilic agent, a hydrophilic agent, wherein the basement membrane disruptor, the vaso-modulator, and the active ingredient pass through the stratum corneum and epidermis. The basement membrane disruptor allows the vaso-modulator and the active ingredient pass through the basement membrane to dermis. The active ingredient, once at the dermis, is delivered locally to the tissue or systemically to the blood stream.
    Type: Grant
    Filed: August 10, 2022
    Date of Patent: January 9, 2024
    Assignees: BioPhysics Pharma, Inc.
    Inventors: John J. Masiz, Zhen Zhu
  • Patent number: 11865218
    Abstract: An embodiment may involve obtaining a three-dimensional image map of m surfaces within an environment, wherein the surfaces are associated with importance weights that represent how frequently the surfaces are expected to be touched; determining a set of n vantage points for a light source within the environment; calculating an m×n irradiance matrix for each of the surfaces when the light source is in each of the vantage points, wherein each entry in the m×n irradiance matrix is determined by: (i) rasterizing the three-dimensional image map, (ii) identifying a set of visible surfaces, and (iii) calculating an amount of light-based power that would reach each of the visible surfaces; determining a set of n dwell times for the vantage points; and providing instructions, to a disinfecting agent, to traverse at least a subset of the vantage points, pausing at and illuminating at least some.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: January 9, 2024
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Kristoffer Karl Hauser, Joao Marcos Correia Marques, Zherong Pan
  • Patent number: 11865219
    Abstract: A concentrated liquid sanitizing and rinse composition containing peroxycarboxylic acid(s) and compatible rinse aid surfactants is disclosed. The sanitizing and rinsing compositions are formulated in a single liquid concentrate, replacing a traditional dual product of a sanitizer and rinse aid. The sanitizing and rinsing chemistries are particularly effective at neutral pHs against gram negative organisms at elevated temperatures. Methods of using the concentrated liquid sanitizing and rinse composition are also disclosed.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: January 9, 2024
    Assignee: ECOLAB USA INC.
    Inventors: Steven J. Lange, Junzhong Li, Xin Sun, Allison Brewster, Richard Staub
  • Patent number: 11865220
    Abstract: A cleaning and sanitizing kit for use in a defined region of a hospital and a method employing the same.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: January 9, 2024
    Assignee: THE TUWAY AMERICAN GROUP, INC
    Inventor: Douglas Koester
  • Patent number: 11865221
    Abstract: Systems and methods provide hand hygiene compliance data at an intelligent hand hygiene device. The system detects that a user is in proximity to the hand hygiene device, then matches the user to one or more user profiles within the system. The system then detects that at least one hand of the user has been placed under a dispensing component of the hand hygiene device, and instructs the dispensing component to dispense hand sanitizer. The system collects compliance data for the user corresponding to hand hygiene compliance, then associates the compliance data for the user with the one or more user profiles corresponding to the user. The system then determines or updates a compliance rate of the user based on the compliance data associated with the user, and transmits the compliance rate of the user to at least one client device associated with a designated user.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: January 9, 2024
    Inventor: Aldo Ivan Novelo Ascencio
  • Patent number: 11865222
    Abstract: A system and method are defined for disinfection of the structure, contents and included air in large volume enclosures such as mass transit vehicles, transport containers, warehouses, and retail sales or gathering locations to reduce the risk of transmission of contagious biological agents, particularly bacterial and viral agents. Various embodiments provide effective sanitizing actions accommodating differing local circumstances and obstacles. Safety interlock mechanisms, procedural steps and communications means ensure safe operations around humans and animals. The system includes a method for measuring environmental conditions to ensure a safe re-entry state.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: January 9, 2024
    Assignee: GMA International Services, Inc.
    Inventor: Robert Baker
  • Patent number: 11865223
    Abstract: A transactional currency sanitizer which includes an enclosure, a deposit device on the enclosure for depositing the currency into said enclosure, an ultraviolet radiation-producing (UV) device with at least two spaced-apart UV light emitters, and a retrieval device on the enclosure for retrieving the currency from said enclosure. The deposit device is configured to receive the currency and pass the currency between the at least two spaced-apart UV light emitters to sanitize both sides of the currency and the retrieval device is configured to accept the sanitized currency from between said device at least two spaced-apart UV light emitters and to provide the sanitized currency for retrieval from said enclosure.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: January 9, 2024
    Inventor: David Alan Poole
  • Patent number: 11865224
    Abstract: The invention provides a novel, versatile degradable hydrogel composition, and methods thereof, with precisely tunable stiffness, plasticity (e.g., degree of covalent vs. physical crosslinks) and predictive disintegration rates degradation, allowing controlled disintegration and release of therapeutic cells or pharmaceuticals and/or in vitro 3D cell expansion.
    Type: Grant
    Filed: May 2, 2022
    Date of Patent: January 9, 2024
    Assignee: University of Massachusetts
    Inventors: Jie Song, Yu Tan, Henry Huang
  • Patent number: 11865225
    Abstract: Disclosed are a sustained-release injection formulation containing a biodegradable polymer double microcapsule that contains a conjugate of poly-L-lactic acid (hereinafter referred to as “PLLA”) filler and hyaluronic acid (hereinafter referred to as “HA”) and is capable of controlling the release rate of PLLA, and a method of preparing the same.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: January 9, 2024
    Assignee: GCS Co., Ltd.
    Inventor: Chang Sik Kim
  • Patent number: 11865226
    Abstract: Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that include particulate structures that are formed from PGS, cerivastatin and everolimus. The particulate structures are configured to modulate inflammation of damaged cardiovascular tissue in vivo by increasing expression of Kruppel like factor 2 (KLF-2), whereby localized expression of monocyte chemoattractant protein 1 (MCP-1) and C-C chemokine receptor type 2 (CCR2) is inhibited at transcriptional and translational levels as a function of the KLF-2 modulation.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: January 9, 2024
    Assignee: CorMatrix Cardiovascular, Inc.
    Inventor: Robert G Matheny
  • Patent number: 11865227
    Abstract: A bone implant comprising cancellous bone that is essentially free of blood cells, and which has been treated with at least one loosening agent, such as collagenase or a digestive enzyme, for a time and at a concentration to loosen the osteogenic cells in the cancellous bone matrix. The osteogenic cells in the matrix are viable cells. The treatment of the cancellous bone with at least one loosening agent enables the osteogenic cells to be more available for carrying out their osteogenic function and to provide for an increased rate of bone formation. Such implant also may include demineralized bone, such as demineralized cortical bone, which enhances the bone regenerative capacity of the cancellous bone.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: January 9, 2024
    Assignee: NuVasive, Inc.
    Inventors: Michelle LeRoux Williams, Charles Randal Mills, Rodney Monroy, Robert A. Zambon, Dayna Buskirk, Earl Fender
  • Patent number: 11865228
    Abstract: The present invention discloses a bone void filler and a method for manufacturing the same by natural calcium-containing waste, which comprises steps of mixing 5-20 wt % of a calcium-containing waste powder, 5-20 wt % of acetic acid and a remaining weight percentage of water uniformly to obtain a mixing solution; adding 5-20 vol % of a diammonium hydrogen phosphate solution to the mixing solution to obtain a suspension; controlling a pH value of the suspension to obtain an alkaline solution; leaving the alkaline solution at room temperature for precipitation for 0.1 to 72 hours, centrifuging or suction filtrating the alkaline solution to obtain a precipitate, drying and grinding the precipitate to obtain hydroxyapatite; and mixing 30-60 wt % of a pore former and 30-60 wt % of the hydroxyapatite and a remaining weight percentage of a binder uniformly to form a mixture, compression molding the mixture in a mold and sintering the compression-molded mixture.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: January 9, 2024
    Assignee: National University Of Kaohsiung
    Inventors: Wen-Fu Ho, Hui-Chun Yu, Shih-Ching Wu, Hsueh-Chuan Hsu, Chi-Jen Chung, Shih-Kuang Hsu
  • Patent number: 11865229
    Abstract: Apparatuses and methods for producing enriched fibrillated tissue matrices are disclosed herein. Some embodiments include a method including subjecting tissue in a carrier liquid to a fibrillation pressure while maintaining a temperature of the tissue and the carrier liquid to at or below a safe zone temperature; inducing a phasic shift and rapid release of water and biological components from the tissue through a disruptive boil and tissue explosion process to produce a fibrillated tissue matrix; and recapturing the water and biological components.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: January 9, 2024
    Assignee: Jupiter Biologics, LLC
    Inventor: Timothy Ganey
  • Patent number: 11865230
    Abstract: The present invention relates to a volatile substance diffuser, where said diffuser comprises a reservoir (10) containing the volatile substances, characterized in that it is formed from a sheet (11) provided with a plurality of fold lines, said sheet (11) comprising a first face (1) on which said reservoir (10) is fixed; a second face (2) which supports the diffuser upright in a use position together with said first face (1); and a third face (3) provided with a hole (12) for hanging the diffuser. The present invention allows providing a volatile substance diffuser which prevents using a container housing said diffuser.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: January 9, 2024
    Assignee: Zobele Holding S.P.A.
    Inventors: Roberto Camarero Díez, Dominic Doyle
  • Patent number: 11865231
    Abstract: A fragrancing system may include at least one cartridge for storing a fragrance and at least one closing mechanism. The cartridge may have a cartridge opening. The closing mechanism may include a flap, a shaft, a lever, and a pin. The flap may be displacable via the shaft to a closed position, in which the flap closes the cartridge opening, and an open position, in which the flap frees the cartridge opening. The fragrancing system may further include an actuating mechanism, which may have a disc rotatable via an actuator. A cam plate structure may project axially from the disc. The pin may be arranged on a radially outward facing outer side of the cam plate structure when the flap is in the closed position and may be engaged with a recess of the cam plate structure when the flap is in the open position.
    Type: Grant
    Filed: February 2, 2021
    Date of Patent: January 9, 2024
    Inventors: Daniel Eberle, Sham Kasar, Sven Petzner, Oliver Schultze
  • Patent number: 11865232
    Abstract: A scattering device includes a position detection unit which detects a position of a user passing through a doorway formed between a first space and a second space adjacent to the first space; a scattering direction determination unit which determines a scattering direction in which liquid, powder, or gas is scattered from proximity of the doorway based on the position of the user detected by the position detection unit; and a scattering unit arranged in the proximity of the doorway to scatter the liquid, the powder, or the gas toward the scattering direction determined by the scattering direction determination unit.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: January 9, 2024
    Assignee: PANASONIC INTELLECTUAL PROPERTY CORPORATION OF AMERICA
    Inventors: Yuri Nishio, Yosuke Akita, Masazumi Watanabe
  • Patent number: 11865233
    Abstract: An air treatment system is provided which includes an appliance and a replaceable cartridge installable therein. The replaceable cartridge contains a liquid compound to be aerosolized and has a cartridge outlet through which the aerosolized compound is discharged during operation. A pump is provided to supply air to the replaceable cartridge to generate the aerosolized compound from the liquid compound contained in the replaceable cartridge, and a controller is provided for controlling the pump to supply the air to the replaceable cartridge to generate and discharge the aerosolized compound from the appliance. The appliance is particularly adapted to be plugged into an electrical wall outlet to be supported by the same within a room for treating the interior air space thereof.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: January 9, 2024
    Assignee: Prolitec Inc.
    Inventor: Nathan Sward
  • Patent number: 11865234
    Abstract: A treatment apparatus for a vehicle comprises: a housing with at least one wall and a floor forming a treatment chamber; a source of ultraviolet light configured to emit ultraviolet light into the treatment chamber; and a door connected to the housing, the door having (i) an open position providing access to the treatment chamber and (ii) a closed position denying access to the treatment chamber and, together with the housing, preventing emitted ultraviolet light from irradiating beyond the treatment chamber.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: January 9, 2024
    Assignee: Ford Global Technologies, LLC
    Inventors: Jay Z. Chen, Anthony Ligi, Jr., John Robert Van Wiemeersch, Michael Hrecznyj, Clay Wesley Maranville, Amy Ellen Langhorst, Rick H. Wykoff
  • Patent number: 11865235
    Abstract: Systems and methods are provided for disinfecting a cabin of a vehicle. In one example, a disinfection system comprises a controller, an ultraviolet radiation source, an air duct, and a steerable optical system. The ultraviolet radiation source is in communication with the controller, disposed within the air duct, and configured to emit ultraviolet radiation. The air duct comprises an inlet configured to receive air particles from within the cabin. The air duct comprises one or more internal reflective surfaces configured to reflect the ultraviolet radiation so as to disinfect the air particles within the air duct. The air duct comprises an outlet configured to transmit the disinfected air particles out of the air duct via the outlet. The steerable optical system is coupled to the air duct and configured to receive and selectively direct the ultraviolet radiation to disinfect the cabin. Additional systems and related methods are provided.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: January 9, 2024
    Assignee: Lyft, Inc.
    Inventors: Joseph Patrick Wendell Whinnery, Azhar Kamal Meyer, Benjamin Patrick Rhoads
  • Patent number: 11865236
    Abstract: An intravenous catheter device can include a safety mechanism having a slider that couples to a catheter adapter and slides relative to a barrel. A needle hub can be contained within the barrel and can be retracted once a catheter has been inserted into the patient's vasculature. The retraction of the needle hub can be triggered by the sliding of the slider. The slider may also function to guard the distal tip of the needle once the needle hub is retracted within the barrel.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: January 9, 2024
    Assignee: Becton, Dickinson and Company
    Inventor: Senthilnathan Kuppusamy
  • Patent number: 11865237
    Abstract: Disclosed herein are a catheter assembly and method of applying a catheter assembly. In an example, the catheter assembly can include a catheter body and frame member extending between proximal and distal portions, the frame member having a first mechanical characteristic, and a floating sleeve coupled around the frame member and extending between the proximal and distal portions, the floating sleeve having a second mechanical characteristic different than the first mechanical characteristic. The floating sleeve can include at least one floating segment and one or more anchor segments along the catheter body. The at least one floating segment of the floating sleeve can be moveable relative to the frame member, and the one or more anchor segments of the floating sleeve can be interconnected with the frame member.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: January 9, 2024
    Assignee: Surmodics MD, LLC
    Inventors: Simon Davis, Michael Reynolds
  • Patent number: 11865238
    Abstract: A simply lockable quick coupling for releasably connecting a hose to an implantable apparatus, comprises a first attachment piece that can be connected to the hose and a second attachment piece that can be connected to the apparatus, wherein the attachment pieces can be rotated relative to each other in the locked state.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: January 9, 2024
    Assignee: ABIOMED EUROPE GMBH
    Inventors: Thorsten Siess, Gerd Spanier
  • Patent number: 11865240
    Abstract: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: January 9, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Goetz Friederichs, Dennis M. Treu, Jeffrey H. Burbank, Yuriy N. Tatashin
  • Patent number: 11865241
    Abstract: A patient monitoring system may be used with catheters to monitor the infusion and drainage of any solution into the human body. The system may be used, for example, with in-dwelling catheters for peritoneal dialysis in end stage renal disease (ESRD) patients, urinary tract catheters, insulin pumps in diabetic patients, feeding tubes and central venous line catheters. The patient monitoring system includes one or more fluid pathways for infusing into and/or draining solutions out of the catheter, and one or more sensors to monitor the fluid. The patient monitoring system transmits the patient monitoring data to a database, allowing data storage, processing, and access through graphical user interfaces to patients and providers via device applications or browser-based web access portals.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: January 9, 2024
    Assignee: GastroKlenz Inc.
    Inventors: Aly R. Elbadry, Eric Hsiang Yu, Ahmad Naim Saleh, Michael Austin Snyder
  • Patent number: 11865242
    Abstract: A medical system includes a reusable apparatus and a disposable fluid circuit, the disposable fluid circuit being coupled to the reusable apparatus and the reusable apparatus being configured to move a fluid through the disposable fluid circuit to perform a procedure. The medical system also includes a controller coupled to the reusable apparatus and configured to control the reusable apparatus to move the fluid through the disposable circuit according to the procedure, to store a procedure record in a memory, to await a procedure termination input, and if the procedure termination input is received, to request at least one input corresponding to a procedure termination reason and to add the procedure termination reason corresponding to the input to the procedure record if received.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: January 9, 2024
    Assignee: Fenwal, Inc.
    Inventors: Steven R. Katz, Dale H. Meixelsperger, Roberto Vilardi
  • Patent number: 11865243
    Abstract: A blood treatment system with pressure sensors may be configured to control blood flow to and from the patient and use readings of the pressure sensors to determine a change in a pressure drop across a flow restriction in the blood circuit to estimate a condition of the machine or the patient, or outputting data responsive to the estimation. Further embodiments employ measurement of pressure drop to detect abnormal viscosity or viscosity variations in order to detect possible infection.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: January 9, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Mark T. Wyeth, Robert Paul McCarty, Gregory Yantz, James Ian Johnson, Joseph E. Turk, Jr., James M. Brugger, Jeffrey H. Burbank
  • Patent number: 11865244
    Abstract: A bodily fluid drainage assembly can include a fluid bag and one or more covers. The assembly can include one or more volume indicators from which an approximate volume of a bodily fluid that is retained within the be can be ascertained. In some arrangements, a cover includes a volume indicator that defines an opening through which a transparent or semitransparent portion of the bag can be viewed.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: January 9, 2024
    Assignee: Stearigear, LLC
    Inventor: Earl G. Christensen
  • Patent number: 11865245
    Abstract: Devices and methods are disclosed for improved irrigation sleeves for ophthalmic instruments to prevent or reduce the likelihood of the irrigation sleeve twisting and/or buckling upon inserting the irrigation sleeve into the eye. In some embodiments, an irrigation sleeve comprises a side opening for irrigation having an elongated shape, wherein the elongated shape is longer in a direction parallel to the longitudinal axis of the distal tube of the irrigation sleeve than in a direction around a circumference of the distal tube of the irrigation sleeve. In some embodiments, an irrigation sleeve comprises at least one rib on an internal surface of the distal end of the irrigation sleeve. In some embodiments, the irrigation sleeve has been subjected to one or more manufacturing steps adapted to stiffen the irrigation sleeve, such as being coated with a stiffening coating or being treated by being exposed to gamma irradiation.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: January 9, 2024
    Assignee: Alcon Inc.
    Inventors: James Y. Chon, Andrea Kim
  • Patent number: 11865246
    Abstract: Presented are apparatus and methods for generating an inhalable medium. An apparatus including a container holding a liquid, a heater for volatizing the liquid, and a plurality of discrete material elements is used. The liquid held in the container is volatized. At least one of a vapor and an aerosol formed by the volatized liquid is passed through one or more of the plurality of discrete material elements. One or more constituents of the one or more of the plurality of discrete material elements is thereby entrained in the at least one of a vapor and an aerosol to produce the inhalable medium.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: January 9, 2024
    Assignee: NICOVENTURES TRADING LIMITED
    Inventors: Richard Hepworth, Dominic Woodcock, Joseph Sutton, Sharon Goodall
  • Patent number: 11865247
    Abstract: An inhaler housing (14) for an inhaler (10) for inhaling inhalable substances, the inhaler having: a body (14) and a dose counter (24) with a return spring (28), wherein a distinct guide surface (162) is provided for guiding the end of the return spring into a recess (152), the distinct guide surface being wider than an entrance mouth (160) of the recess, a dose counter chamber (22) being provided which is separated from a tubular interior space (182) of the inhaler by a barrier (180), the barrier including a stepped upper wall area (184) including at least three steps (186, 188, 190, 192) at different levels, the inhaler having a valve stem block (62) having an inner bore and a valve stem block having a seal (224) in the inner bore with a second diameter which is smaller than a first diameter of the inner bore, the inhaler having a canister (150) being adapted to move during operation between 1 and 4 mm, a drive being arranged to apply a firing force of between 15N and 60N of force to the canister at a posit
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: January 9, 2024
    Assignee: NORTON (WATERFORD) LIMITED
    Inventors: Daniel Buck, Paul Prendergast, Declan Walsh
  • Patent number: 11865248
    Abstract: Disclosed herein is an aerosol delivery device including an air inlet a flavoring reservoir arranged to provide release of flavoring material to air passing therethrough; and an aerosol forming member arranged to provide an aerosol in air, wherein the aerosol forming member includes a heating element and an aerosol outlet wherein the air inlet, the flavoring reservoir, the aerosol forming member and the aerosol outlet are arranged in fluid communication in that order; wherein the flavoring reservoir is in conductive thermal communication with the heating element and wherein the flavoring reservoir is arranged at least partially about, or at least partially surrounding, the aerosol forming member.
    Type: Grant
    Filed: October 27, 2021
    Date of Patent: January 9, 2024
    Assignee: NICOVENTURES TRADING LIMITED
    Inventor: Helmut Buchberger
  • Patent number: 11865249
    Abstract: An inhalation-synchronized fluid dispenser device having a body, a reservoir containing a fluid and a propellant gas that slides axially in the body, a metering valve, a blocking element movable and/or deformable between a non-actuation position and an actuation position, and an inhalation-controlled trigger system that moves and/or deforms the blocking element from the non-actuation position towards the actuation position. The device includes an actuator fastened on the reservoir and having a proximal wall fastened on the end of the reservoir, a body that slides axially past the proximal wall, and a spring arranged between the proximal wall and a distal wall of the body, the body sliding axially past the proximal wall between a rest position and a cocked position in which the spring is compressed, such that on actuation of the trigger system, the compressed spring moves the reservoir so as to actuate the metering valve.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: January 9, 2024
    Assignee: APTAR FRANCE SAS
    Inventor: Ludovic Petit
  • Patent number: 11865250
    Abstract: A hand-held, portable inhalator device is disclosed. The device has a mouthpiece with a chamber operatively coupled to a medication inlet and a fluid outlet. A trigger is configured to dispense medication from a medication source through the medication inlet and into the chamber after a threshold level of positive pressure is achieved within the chamber of the mouthpiece and maintained for a threshold period of time.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: January 9, 2024
    Inventor: John R. Collins
  • Patent number: 11865251
    Abstract: The e-vaping device includes a vaporizer assembly, which includes a heating element, a pre-vapor formulation reservoir, a pre-vapor formulation level indicator including a plurality of discrete indicator segments, and at least one processor. The pre-vapor formulation reservoir may be configured to contain a pre-vapor formulation and the at least one processor may be configured to determine a difference between a first duty cycle of power supplied to the heating element and a second duty cycle of power supplied to the heating element; and adjust the indicator based on the determined duty cycle difference.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: January 9, 2024
    Assignee: ALTRIA CLIENT SERVICES LLC
    Inventors: Terrance Theodore Bache, Christopher S. Tucker, Raymond W. Lau
  • Patent number: 11865252
    Abstract: A fluid dispenser assembly having a nasal fluid dispenser device (1000) with a reservoir (30) and, a dispenser head (1) assembled on the reservoir (30); a remote mobile device (2000); and an orientation sensor (113) to obtain optimal orientation of the dispenser device (1000) when actuated. The sensor determines the three-dimensional orientation of the device, including the angle (?) of the device relative to said remote mobile device. A second sensor (121) is provided for detecting when the device (1000) is actuated by the user. The remote mobile device includes an accelerometer to determine its position in three-dimensional space, in particular the angle (?) of the remote mobile device (2000) relative to the vertical.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: January 9, 2024
    Assignee: APTAR FRANCE SAS
    Inventors: Matthieu Norrant, Maxime Huppé
  • Patent number: 11865253
    Abstract: The present invention relates to methods for operating a respiration apparatus and a respiration system, and also a respiration apparatus and a respiration system. The respiration system comprises a respiration apparatus and a computer software program for an external computer to operate the respiration apparatus. The respiration apparatus comprises a processor device and an apparatus software program and an apparatus configuration. The validities of the computer software, the apparatus software and the apparatus configuration are in each case characterized by a version. The versions are compared with one another to detect a version conflict. If invalid versions are present, the computer software is provided with a program component with a limit value and a plausibility rule, or the setting parameters are sorted into a first group and a second group. The setting parameters of the first group are retained.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: January 9, 2024
    Assignee: Loewenstein Medical Technology S.A.
    Inventors: Igor Bychkov, Florian Stockwald
  • Patent number: 11865254
    Abstract: An oscillating positive expiratory pressure apparatus having a housing defining a chamber, a chamber inlet, a chamber outlet, a deformable restrictor member positioned in an exhalation flow path between the chamber inlet and the chamber outlet, and an oscillation member disposed within the chamber. The deformable restrictor member and the oscillation member are moveable between an engaged position, where the oscillation member is in contact with the deformable restrictor member and an disengaged position, where the oscillation member is not in contact with the deformable restrictor member. The deformable restrictor member and the oscillation member move from the engaged position to the disengaged position in response to a first exhalation pressure at the chamber inlet, and move from the disengaged position to an engaged position in response to a second exhalation pressure at the chamber inlet.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: January 9, 2024
    Assignee: Trudell Medical International
    Inventors: Jerry Grychowski, Martin P. Foley
  • Patent number: 11865255
    Abstract: A ventilator is configured to supply a gas mixture to the lungs of a subject. The gas mixture comprises a first gas (e.g. oxygen) and a second gas (e.g. ambient air). The ventilator comprise a first gas inlet, a second gas inlet, flow modulator of the first gas, a flow modulator of the second gas, a junction configured to mix the first gas and the second gas, a patient interface configured to deliver the gas mixture to a subject, a pressure sensor, a plurality of flow sensors comprising at least a first flow sensor and a second flow sensor, and at least one controller configured for obtaining data from the pressure sensor and flow sensors and controlling the flow modulators to provide a gas mixture having a target pressure and a target oxygen content.
    Type: Grant
    Filed: March 14, 2022
    Date of Patent: January 9, 2024
    Assignee: Invent Medical Corporation
    Inventor: Samuel M. Chang
  • Patent number: 11865256
    Abstract: A resuscitation device is described that can include an electronic circuit board, a shaft that is operably coupled with the electronic circuit board and has a head, a gas-bag adjacent to the head and configured to store gas, and a valve operably coupled to the gas-bag. The electronic circuit board can actuate the shaft to move. The moving of the shaft can cause the head to compress the gas-bag. The compression of the gas-bag can cause the gas-bag to release gas. Related apparatuses, systems, methods, techniques and articles are also described.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: January 9, 2024
    Assignee: The Aga Khan University
    Inventors: Saleem Sayani, Muhammad Abdul Muqeet, Hafiz Imtiaz Ahmed, Naeem Sheikh, Sannan Ahmed Qureshi, Huba Atiq, Syeda Zoha Raza, Khawaja Mohammad Inam Pal, Syed Shujaat Hussain, Maleeha Naseem, Amna Jawaid, Jonathan Johnson
  • Patent number: 11865257
    Abstract: Disclosed is an ICU-special portable nebulization device enabling autonomous respiration according to airflow, which includes a nebulization control host, a nebulization generator provided on the nebulization control host, and a tee connecting pipe provided on the nebulization generator; the nebulization generator comprises a bottom housing, a medicinal solution tank provided on the bottom housing and spaced apart from a space of the bottom housing, a medicinal solution outlet provided on the bottom of the medicinal solution tank, an air guide port provided on the bottom housing at the same side as the medicinal solution outlet, a nozzle tube sheathed on the periphery of the medicinal solution outlet and the air guide port, a partition provided in the nozzle tube which separates the medicinal solution outlet and the air guide port.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: January 9, 2024
    Assignee: FEELLIFE HEALTH INC.
    Inventors: Jian Hua, Xuefeng Song
  • Patent number: 11865258
    Abstract: A data processing method and device based on a positive pressure ventilation therapy machine is described. The method comprises: acquiring a current operating parameter and a current pressure value of a draught fan in the positive pressure ventilation therapy machine; finding a target relational expression corresponding to the current pressure value in a preset list according to the current pressure value, wherein the preset list comprises a plurality of pressure values and relational expressions corresponding to the plurality of pressure values, and each of the relational expressions corresponding to the plurality of pressure values is a relational expression between operating parameters of the draught fan and a gas flow output by the positive pressure ventilation therapy machine; and determining a current gas flow output by the positive pressure ventilation therapy machine according to the current operating parameter and the target relational expression.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: January 9, 2024
    Assignee: BMC MEDICAL CO., LTD.
    Inventors: Zhi Zhuang, Weifeng Liu
  • Patent number: 11865259
    Abstract: A device and a method for respiratory therapy. The device is configured with at least two operating modes, which include a first operating mode for providing HFNC support for a patient and a second operating mode for providing NIV support or INV support for the patient; the device includes a memory stored with instructions and a processor, the processor is configured to call and run the instructions stored in the memory to execute operations of: obtaining an ROX index based on first parameters; and triggering mode switching of the device according to the ROX index and a preset triggering strategy for switching the operating mode of the device.
    Type: Grant
    Filed: December 28, 2022
    Date of Patent: January 9, 2024
    Assignee: Telesair, Inc.
    Inventors: Bo Li, Yong Liu
  • Patent number: 11865260
    Abstract: A patient interface assembly includes an elastomeric piece configured to receive a flow of pressurized respiratory gas and sealingly engage the patient's face. The elastomeric piece forms a plenum and includes a mouth sealing portion, a nasal sealing portion, and an anterior surface with an air inlet opening configured to be coupled to a connector and/or an air delivery tube. The patient interface assembly also includes a stiffening structure that is attached to the anterior surface of the elastomeric piece. The stiffening structure comprises a central aperture that is sized so that the air inlet opening and a portion of the anterior surface surrounding the air inlet opening remain exposed through the central aperture. The stiffening structure is configured so that the entirety of the stiffening structure is inferior to the patient's nose in use.
    Type: Grant
    Filed: May 25, 2023
    Date of Patent: January 9, 2024
    Assignee: ResMed Pty Ltd
    Inventors: Justin John Formica, Jose Ignacio Romagnoli, Philip Rodney Kwok, Joel Edward Gibson, David Anthony Pidcock, Christopher Scott Skipper, Stephen Gray
  • Patent number: 11865261
    Abstract: A respirator mask that includes a body, a nasal interface, and a mouthpiece. The body defines an exterior surface and an interior space. The mouthpiece includes an inner channel that is insertable into a human mouth, wherein the inner channel extends outward from the exterior surface of the body and defines an opening into the interior space. The nasal interface includes a recessed portion that is recessed into the body and is configured to receive at least part of a human nose. The nasal interface further includes a pair of nozzles, wherein each nozzle of the pair of nozzles is insertable into a nostril of a wearer and defines an opening into the interior space.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: January 9, 2024
    Inventor: Mark Lamoncha
  • Patent number: 11865262
    Abstract: Methods and apparatus for administering oxygen therapy, and particularly high-flow oxygen therapy is disclosed herein. A respiratory monitoring system may non-invasively determine average peak inspiratory flow rate of a patient based on biofeedback response received from the patient. Medical air, oxygen, or a combination of both may be delivered to the patient at a flow rate equal to greater than the determined average peak inspiratory flow rate of the patient to meet or exceed inspiratory demand of the patient. Fraction of oxygen inspired by the patient may be determined based on the average peak inspiratory flow rate and may be adjusted through high-flow oxygen therapy meeting inspiratory demand to prevent entrainment of ambient air or through low-flow oxygen therapy by accounting for entrainment of ambient air based on the average peak inspiratory flow rate to address medical needs of the patient.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: January 9, 2024
    Inventor: Jeff Majdali
  • Patent number: 11865263
    Abstract: Patient interface components and/or associated head gear and adjustment systems improve sealing and/or patient comfort and/or ease of use. The interface comprising an inflating or ballooning seal. The headgear assembly can be connected to the interface with an elastic component and an inelastic component. The elastic component enabling a course fitting of the interface to the patient and the inelastic component enabling a final fitting of the interface to the patient.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: January 9, 2024
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Daniel John Smith, Brett John Huddart, Matthew James Adams, Nicholas Alexander Hobson, Timothy James Beresford Sharp, Roheet Patel, Gregory James Olsen, Matthew Roger Stephenson, Troy Barsten
  • Patent number: 11865264
    Abstract: A moisture removal apparatus for a breathing circuit may include a breathing gas conduit configured to receive a flow of breathing gas having a first humidity level. The apparatus may include a dry gas conduit adjacent to at least a portion of the breathing gas conduit, the dry gas conduit configured to receive a flow of dry gas having a second humidity level lower than the first humidity level. The apparatus may also include a feeding conduit extending through at least a portion of the dry gas conduit, the feeding conduit configured to introduce the dry gas into the dry gas conduit. The apparatus may further include a moisture transmission pathway configured to enable transfer of moisture from the breathing gas to the dry gas based on the humidity differential.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: January 9, 2024
    Assignee: Medline Industries, LP
    Inventors: Daniel Patrick Dwyer, James Lorek
  • Patent number: 11865265
    Abstract: An anti-explosion gas generator for health use is provided. The anti-explosion gas generator for health use includes an electrolysis device for electrolyzing water to produce a gas mixture of hydrogen and oxygen. The gas generator for health use further includes a gas mixing system coupled to the electrolysis device for receiving the gas mixture. The gas mixing system mixes the gas mixture with water vapor, an atomized medicine, a volatile essential oil or a combination thereof to produce a health gas. The health gas is provided for being inhaled by a user.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: January 9, 2024
    Inventor: Hsin-Yung Lin
  • Patent number: 11865266
    Abstract: A flow regulating valve for a respiratory treatment system is disclosed, as well as a vent arrangement comprising the flow regulating valve. The flow regulating valve may include an inlet, an outlet, and a variable conduit in fluid communication with the inlet and the outlet. The variable conduit may include a movable portion that may move to vary an impedance of the variable conduit, thereby regulating a flow rate of the air travelling through the variable conduit. Advantageously, the flow regulating valve may thus reduce wastage of air (e.g. humidified air) that is exhausted from a respiratory treatment system, while maintaining sufficient washout of air.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: January 9, 2024
    Assignee: ResMed Pty Ltd
    Inventors: Liam Holley, Barton John Kenyon, Gordon Joseph Malouf, Luke Andrew Stanislas
  • Patent number: 11865267
    Abstract: A control system provides automated control of gas washout of a patient interface, such as a mask or nasal prongs. A gas washout vent assembly of the system may include a variable exhaust area, such as one defined by gears, radial exhaust revolvers and/or flow diverters for a conduit having a variable gas passage channel. The vent assembly may be attached substantially near or included with the patient interface. An actuator of the assembly, such as a solenoid, motor or voice coil, manipulates the vent assembly. The actuator may be configured for control by a processor to change the exhaust area of the vent assembly based on various methodologies including, for example, sleep detection, disordered breathing event detection and/or leak detection.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: January 9, 2024
    Inventors: David Brent Sears, Steven Paul Farrugia, Aleksandr S. Nagorny, Richard G Krum, Joseph M Sampietro