Abstract: The reverse osmosis centrifuge converts rotational energy into fluid velocity and conserves the energy placed into the concentrate. As concentrate travels back towards the center of the reverse osmosis centrifuge, the velocity of the fluid is converted into rotational force, thus conserving energy. To accomplish this, the reverse osmosis centrifuge includes a stationary cylindrical housing having a vacuum chamber and a vacuum pump for generating vacuum pressure in the vacuum chamber, a driveshaft coupled to a membrane cylinder rotatable within the stationary cylindrical housing, the membrane cylinder having a plurality of vertical desalination membranes, and an energy recovery turbine. The reverse osmosis centrifuge can be placed on the concentrate or waste stream outlet of a desalination or reverse osmosis facility to increase freshwater production. Through using the methods described above, plant water production can be increased up to 40%, which in turn has a dramatic effect on plant profitability.

Abstract: A control method uses in a membrane filter system operated in iterative filtration cycles, the cycles including a production period and a following flushing. A setting of a crossflow on the entrance side (4) of a membrane (2) in the production period is controlled such that the energy consumption (E) per filtration cycle reaches an optimum. A corresponding membrane filter system is provided.

Abstract: Dual phase membranes include a porous support providing a solid phase having a matrix of connected pores, and a liquefiable ion transport phase within the pores of the porous support. The ion transport phase is formed of at least one alkali metal hydroxide, and at least one oxide ion transport agent providing a source of ions selected from the group consisting of borate ions, nitrate ions, phosphate ions, vanadate ions, niobate ions or sulfate ions. The at least one alkali metal hydroxide may be selected from the group consisting of NaOH, KOH, LiOH, RbOH, CsOH and mixtures thereof. The oxide ion transport agent is preferably present in the ion transport phase in an amount between about 1 to about 30 molar %. Substantially lower operational temperatures may be realized when the membrane is used to separate CO2 from a feed gas.

Abstract: Systems and methods for catalyzed asymmetric bipolar membranes are described. Catalyzed asymmetric bipolar membranes can sustain desired current densities under low operational voltage for prolonged time periods. Catalyzed asymmetric bipolar membranes can be implemented in electrodialysis cells for various applications such as carbon capture.

Abstract: A method for producing an asymmetric porous membrane includes: forming a first casting film from a casting solution on a carrier, the casting solution containing a hydrophobic polymer, a hydrophilic polymer, a water-soluble polymer, and a solvent; placing the first casting film in an environment containing water vapor to contact the first casting layer with the water vapor, thereby obtaining a second casting film, the environment having a temperature ranging from 20° C. to 33° C. and a relative humidity of 30% to 80%; and contacting the second casting film with a coagulating agent so as to perform a wet-phase inversion. The hydrophilic polymer is polyvinylpyrrolidone, polyalkylene glycol, or a combination thereof. The water-soluble polymer is a copolymer of vinylpyrrolidone and vinyl acetate, a copolymer of vinylpyrrolidone and alkylene glycol, a vinyl alcohol-based polymer, an ethylene glycol/propylene glycol based copolymer, an ethyleneimine-based polymer, a water-soluble cellulose, or combinations thereof.

Abstract: Disclosed are a polyolefin resin composition usable in manufacturing a single-layered dry porous membrane having excellent meltdown and shutdown properties, and a porous membrane using the polyolefin resin composition. The present invention provides a polyolefin resin composition for a porous membrane, wherein the polyolefin resin composition includes 30 wt % to 70 wt % of a high-density polyethylene having a melt flow index (190° C., 2.16 kg load) of 0.1 g/10 min to 5 g/10 min, a crystallization temperature of 115° C. to 125° C., and a degree of crystallinity of 75% or greater, and 30 wt % to 70 wt % of a high-crystallinity polypropylene having a melt flow index (230° C., 2.16 kg load) of 5 g/10 min to 20 g/10 min.

Abstract: Nanoporous selective sol-gel ceramic membranes, selective-membrane structures, and related methods are described. Representative ceramic selective membranes include ion-conductive membranes (e.g., proton-conducting membranes) and gas selective membranes. Representative uses for the membranes include incorporation into fuel cells and redox flow batteries (RFB) as ion-conducting membranes.

Abstract: The present disclosure provides a preparation method of a reverse osmosis composite membrane, including the following steps: coating a gelatin solution on a non-woven fabric layer and cooling to form a gelatin gel layer; coating a salt solution on a surface of the gelatin gel layer to obtain a gel/non-woven fabric composite membrane; placing the gel/non-woven fabric composite membrane in an aqueous phase solution, transferring into an oil phase solution, and conducting interfacial polymerization to obtain a non-woven fabric/gel/polyamide composite membrane; placing the non-woven fabric/gel/polyamide composite membrane in water, and heating to remove the gelatin gel layer to obtain a non-woven fabric/polyamide composite membrane; and introducing a trimesoyl chloride (TMC) gas from a side where the non-woven fabric layer is away from a polyamide layer in the non-woven fabric/polyamide composite membrane, conducting gas-liquid interfacial polymerization by chemical vapor deposition (CVD), and drying to obtain th

Abstract: Embodiments described in examples herein provide a gas separation membrane including a polyimide polymer including a monomer having a structure including: wherein when X1=X2, X1 and X2 are selected from F, Cl, Br, or I and wherein when X1 and X2 are different elements, X1 and X2 are independently selected from H, F, Cl, Br, or I.

Abstract: Disclosed are techniques to mimic turbulent-enhanced reactivity under confinement by the addition of dilute high molecular weight polymers. Micro-scale imaging within a transparent porous medium reveals an elastic instability (EI), which drives chaotic fluctuations that stretch and fold solute blobs exponentially in time analogous to turbulent Batchelor mixing, despite the low Re. A reduction in the required mixing length can be observed, suggesting a cooperation between the elastic instability and the dispersion inherent to the disordered 3D porous media—which can be modeled as additive independent mixing rates, representing a dramatic conceptual simplification. The disclosed enhanced transport of solutes circumvents the traditional trade-off between throughput and reactor length, allowing a simultaneous large reduction in length and increases in throughput.

Abstract: The present disclosure provides a microchannel liquid-liquid mixing device, comprising a microchannel component and a shell, wherein the microchannel component is fixed inside the shell, wherein an inlet is provided at one end of the shell for feeding at least two reaction liquid phases, and an outlet is provided at the other end for discharging a mixed material; said microchannel component comprises multiple stacked sheets and oleophilic fiber filaments and hydrophilic fiber filaments filled in the crevices between adjacent sheets, wherein the fiber filaments form several microchannels between them, and the fiber filaments are clamped and fixed by the sheets. The microchannel liquid-liquid mixing device is used for at least two reaction liquid phases to form a mixed material, and the at least two reaction liquid phases are cut by fiber filaments and mixed in the microchannel mixing device to form a mixed material.

Abstract: A system for bone cement includes a vial holder configured for receiving a vial and including a holding structure for maintaining the vial in the vial holder. The vial includes a monomer component for bone cement. A holder chamber is configured to receive and secure the vial holder. The vial holder is advanced toward a vial-breaking device for breaking the vial and releasing its contents into the holder chamber past the elastomeric seal. Once the vial holder is advanced further the elastomeric seal is deformed to form a seal and prevent fumes produced from escaping from the device.

Abstract: The present invention is directed to a membrane reactor for the hydrogenation of carbon dioxide, said membrane reactor comprising a reaction compartment (2) comprising a catalyst bed, a permeate compartment (4) and a membrane separating the reaction compartment and the permeate compartment, wherein said permeate compartment comprises a condensing surface.

Abstract: A method of assembling and/or operating apparatus for undertaking a chemical reaction. The apparatus includes a housing in which a precursor of a receptacle is arranged. A fluid (F1) may be introduced into said precursor to cause the precursor to inflate.

Abstract: The present disclosure is directed to systems and methods for direct electrical heating of process heaters tubes (e.g., reactor tubes) using galvanic isolation techniques. The disclosure is also directed to systems and methods for direct electrical heating of process heaters tubes wherein the tubes are galvanically isolated in such a manner as to avoid the use of electrical insulation of the tube from the rest of the system, such as the other tubes, the tube inlet header and/or the tube outlet header, and the reactor shell.

Abstract: Provided is a burner arrangement for producing synthesis gas by non-catalytic or catalytic partial oxidation of fluid or fluidized carbon-containing fuels in the presence of an oxidant and a moderator, including following assemblies: (a) a feeding means for separately feeding three fluid reaction media streams or two fluid and one fluidized reaction media stream into a burner, (b) at least one burner, (c) outer wall of the at least one burner is fluid-tightly connected to a burner mounting plate, (d) a reaction chamber, (e) the at least one burner is insertable into the reaction chamber, and (f) outer wall of the at least one burner and the side of the at least one burner mounting plate facing away from the interior of the reaction chamber are designed to allow cooling by indirect heat exchange with a cooling fluid.

Abstract: A supported riser apparatus may be housed at least partially within a vessel. The supported riser apparatus may include a riser including a non-vertical riser segment, a non-linear riser segment, and a vertical riser segment. The supported riser apparatus may further include a support member comprising a proximal end and a distal end. The proximal end of the support member may be connected to the non-vertical riser segment and the angle between the support member and the non-vertical riser segment may be from 15 to 75. The supported riser apparatus may include a support structure connected to the riser and the support member and an expansion guide connected to an interior surface of the vessel. The expansion guide may be shaped and positioned such that the support member slides across the expansion guide as the support member undergoes thermal expansion or thermal contraction.

Abstract: According to one or more embodiments of the present disclosure, a riser may include a lower riser portion, where the lower riser portion terminates at an upper end of the vertical riser segment, and an upper riser portion including a lower end, where the lower end of the upper riser portion may be positioned around the upper end of the vertical riser segment of the lower riser portion. The riser may also include a first guide and a second guide each positioned on opposite sides of the interior of the lower end of the upper riser portion. The vertical riser segment of the lower riser portion may be guided in a direction substantially parallel with the outer surface of the first guide and the outer surface of the second guide when the lower riser portion expands or contracts due to changes in temperature.

Abstract: A method of making colloidal crystals using seed programmable atom equivalents (PAEs) and growth programmable atom equivalents (PAEs) for at least two stage growth. The seed and growth PAEs each include nanoparticles functionalized with oligonucleotides with sticky ends. Seed PAEs have sticky ends adapted to hybridize to each other to form a first duplex, and growth PAEs have sticky ends adapted to hybridize to a respective ones of the seed PAEs and to each other to form second, third, and fourth duplexes. Using base mismatches in the sticky ends of the growth PAEs and a two stage cooling, the first duplex having a higher melting temperature than the other duplexes nucleate the seed PAEs as seeds in a first stage and remaining duplexes form in a second lower temperature stage for growth on the seeds.

Abstract: The present teachings relate to a method for monitoring a production process for manufacturing a chemical product at an industrial plant, the method comprising: providing an up-stream object identifier comprising input material data, receiving real-time process data from one or more of the equipment zones; determining a subset of the real-time process data based on the upstream object identifier and a zone presence signal; computing at least one zone-specific performance parameter of the chemical product related to the up-stream object identifier based on the subset of the real-time process data and historical data; appending, to the upstream object identifier, the at least one zone-specific performance parameter. The present teachings also relate to a system for monitoring a production process, a dataset, use, a method for generating the dataset and a software program for the same.

Abstract: The present application relates to methods and apparatus for delivering liquid or solid feedstocks into a plasma treatment vessel. More specifically, the invention provides a method for treating a sample using glow discharge plasma in an apparatus comprising a treatment vessel, the method comprising (i) delivering a gaseous plasma forming feedstock into the treatment vessel through a gas supply line under the control of a gas flow controller, and causing formation of a glow discharge plasma in the treatment vessel from the gaseous plasma forming feedstock; and simultaneously (ii) delivering a reagent into the treatment vessel under the control of a reagent dosing controller, wherein the reagent is a liquid or a solid; and (iii) contacting the sample with the glow discharge plasma and the reagent; wherein the gas flow controller and the reagent dosing controller allow independent control of the rate of delivery of the gaseous plasma forming feedstock and the reagent.

Abstract: The present invention relates to a method for treating a sample using glow-discharge plasma comprising one or more treatment steps, in which the sample for treatment is subject to plasma treatment in a treatment vessel provided with a temperature control system, wherein during the one or more treatment steps the treatment vessel is rotated about an axis in order to agitate the sample and the temperature control system is used to cool or heat the sample. The present invention also relates to an apparatus for use in such a method.

Abstract: Many industrial processes take place often under high temperatures. One of the greatest problems is overheating of surrounding structural elements in contact with hot gases. This increases the thermal load on materials and reduces the service life of constructions. The construction of efficient cooling systems is very complex and time-consuming and presents a technical challenge. The invention addresses the problem of providing a method, which ensures separation of hot gases from construction walls while allowing high gas temperatures to be achieved in the working region. The problem is solved with a method, which is characterized in that a hot gas is kept in continuous rotation in a chamber, wherein the rotating gas forms a thermally insulating gas layer due to the effect of centrifugal force, and overheating of the chamber walls is avoided thereby. Using the invention can significantly reduce heat losses and thus energy consumption. Higher efficiencies can be achieved.

Abstract: A nanocomposite sorbent which contains molybdenum carbide, molybdenum nitride, and molybdenum oxide. The nanocomposite sorbent is in the form of nanosheets having a mean size of 10 to 100 ?m and a mean thickness of 10 to 1000 nm. A method of forming the nanocomposite sorbent is also provided. The nanocomposite sorbent is used to form a membrane filter with a fluorinated polymer. The nanocomposite sorbent and membrane filter are each used in a method of removing an organic pollutant from water.

Abstract: Disclosed are a modified nanoscale zero-valent iron (nZVI) and a preparation method and an application thereof. The preparation method of the modified nZVI includes the following steps: S1: mixing nZVI, a stabilizer and an oxidant together and stirring in an inert atmosphere to obtain a polymerization precursor solution; and S2: dripping pyrrole into the polymerization precursor solution prepared in the S1, maintaining an inert gas atmosphere for polymerization reaction, and performing cooling, filtration and vacuum drying to obtain the modified nZVI.

Abstract: An object of the present invention is to provide an activated carbon that can efficiently remove fluorine-containing organic compounds and a treatment method of water containing fluorine-containing organic compounds. An activated carbon according to an aspect of the present invention has an average particle diameter of 0.1 to 10 mm, a BET specific surface area of 500 m2/g or more and 2000 m2/g or less, and a porosity inside a particle of 10% or more and 40% or less as obtained by X-ray CT. A water treatment method according to another aspect of the present invention includes a step of bringing the activated carbon into contact with water to be treated containing a fluorine-containing organic compound to obtain treated water having a fluorine-containing organic compound content of 0.1 ppb or less.

Abstract: There is provided herein a method of reducing the backwash frequency required in water treatment facilities which includes utilizing a surface-modified activated carbon. A method of preparing said surface-modified activated carbon is also provided. The method of preparing may include oxidizing an activated carbon with a chemical oxidant, which may result in surface functionalization of the activated carbon.

Abstract: A product for adsorbing one or more PFAS from a liquid is disclosed. The product may comprise attapulgite or sepiolite that has been surface functionalized with (a) a quaternary amine surface coating solution that comprises a mono-quaternary amine compound or a di-quaternary amine compound and (b) a mercapto surface coating solution that comprises a surface coating agent that includes one or more mercapto groups that chemically bond to the attapulgite or sepiolite surface. When the quaternary amine surface coating solution includes the mono-quaternary amine compound, the product is free of di-quaternary amines. When the quaternary amine surface coating solution includes the di-quaternary amine compound, the product is free of mono-quaternary amines. Also disclosed is a method of producing the product and a method of adsorbing a PFAS in a liquid using the product.

Abstract: Metal organic frameworks are provided that exhibit a reversible phase change from a collapsed state to an expanded state. Due to this material property, these adsorbents exhibit stepped isotherms that have relevance in chemical storage and separations. The metal organic framework is M(LDP), where M is a metal selected from the group of Zn, Fe or Co and L is a ligand selected from the group of 1,4-benzenedipyrazolate (H2BDP), 2,5-pyridinedipyrazolate (H2PyDP), 2,5-pyrimidinedipyrazolate (H2PymDP), 2,5-pyrazinedipyrazolate (H2PyzDP), and 3,6-pyridazinedipyrazolate (H2PydDP). The step pressure position in the isotherm was changed by using nitrogen instead of carbon in the ring allowing for tunable aromatic interactions.

Abstract: Supported amine polymer adsorbents based on polymers containing only or primarily primary amines sites are to be used as regenerable adsorbents for CO2 capture from ultra-dilute gas streams, such as ambient air, or from mixtures of gases containing preferably at least I 0% oxygen. and can also be useful for use at the moderate gas pressures found in typical post-combustion capture processes, such as flue gas from large point sources such as coal-fired power plants. Preferred supported solid amine adsorbents of this invention are based on poly(allylamine) (“PAA”) and poly(vinyl amine) (“PVAm”), both of which are linear polymers, and their derivatives, containing substantially all primary amine groups, supported on substrates. Preferred such substrates include silica mesocellular foam (MCF) and mesoporous-.gamma.-alumina, as well on mesoporous-.gamma.-alumina coated throughout the pores of MCF, most preferably of monolithic structure.

Abstract: A product includes an aminopolymer material formed into a self-supporting structure, the aminopolymer material including crosslinked aminopolymers having amine sites for the capture of carbon dioxide molecules.

Abstract: A structure includes a water-insoluble fiber, and a low-molecular-weight antibody connected to the water-insoluble fiber. A method of producing a structure includes connecting a water-insoluble fiber and a low-molecular-weight antibody to each other.

Abstract: A polymer aerogel monolith comprising a polymer aerogel having a nitrogen content of greater than seven weight percent impregnated into a mesh. A method of manufacturing an amine-containing polymer aerogel monolith, includes combining a vinyl-containing cross-linking monomer, a vinyl-containing functional monomer, an organic solvent, and a radical initiator into a liquid mixture, applying the liquid mixture to a mesh fabric to produce a monomer-impregnated mesh, heating the monomer-impregnated mesh to produce a polymer aerogel monolith, washing the polymer aerogel monolith with acid to produce an ammonium-containing polymer aerogel monolith, and applying a base to neutralize the ammonium-containing polymer aerogel monolith to produce an amine-containing polymer aerogel monolith.

Abstract: Processes for regenerating sorbents at high temperatures, and associated systems, are generally described.

Abstract: The disclosure relates to systems and methods for generating a brine solution using a canister for recharging zirconium phosphate in a reusable sorbent module. The canister can include salt and have an inlet and an outlet. The inlet can extend upwardly into an interior of the canister above solid sodium chloride and sodium acetate. Water can be added to dissolve the salts in the canister and the resulting solution can be collected as a brine solution for use in recharging the zirconium phosphate.

Abstract: The present invention deals with a catalyst for converting CO by the reaction of water gas shift at high temperature, free of chromium and iron, consisting of alumina promoted by potassium and zinc oxide. The catalyst prepared in this way maintains a high CO conversion activity, not having the environmental or operating limitations with low excess steam in the process, which exist for state of the art catalysts. Such a catalyst is used in the process of producing hydrogen or synthesis gas by steam reforming hydrocarbons, allowing the use of low steam/carbon ratios in the process, presenting high activity and stability to thermal deactivation and lower environmental restrictions on production, storage, use and disposal, than catalysts used industrially based on iron, chromium and copper oxides.

Abstract: Disclosed herein are compositions having enhanced oxygen storage capacity (OSC). The OSC enhanced compositions contain cerium, zirconium, lanthanum, and neodymium, and a dopant element selected from the group consisting of Ti, Mn, Fe, Co, Cu, Zn, Ga, Ge, Ta, W, Mo, Nb, In, Sn, Ba, and mixtures thereof. In certain embodiments, these compositions contain two dopants. In certain embodiments of these compositions, the compositions comprising cerium, zirconium, lanthanum, and neodymium and one or more dopant elements have an OSC after aging at 1000° C. for 10 hours which is improved by 1 to 50%, compared to an undoped composition comprising cerium, zirconium, lanthanum, and neodymium. Aging can be conducted in an air environment. Further disclosed are processes of producing these compositions having enhanced oxygen storage capacity (OSC). The compositions can be used as a catalyst.

Abstract: A conditioning process that is employed with a high selectivity catalyst (HSC) during an initial phase (i.e., start-up) of the epoxidation process is provided. The HSC conditioning process of the present disclosure ensures that the heat release from a catalyst bed containing an HSC during a start-up operation is less than 2000 kJ/Kgcat·hr. The HSC containing catalyst bed that has been conditioned by the process of the present disclosure exhibits improved performance (i.e., EO selectivity) and reduced hot spots.

Abstract: The objective of the present invention is to provide an ammonia decomposition catalyst that is capable of efficiently decomposing ammonia into nitrogen and hydrogen and that has high mechanical strength, and a method for producing hydrogen and nitrogen by using the ammonia decomposition catalyst. The ammonia decomposition catalyst according to the present invention is characterized in comprising cobalt (A); one or more rare earth elements (B) selected from cerium, yttrium and lanthanum; one or more alkaline-earth metal elements (C) selected from barium and strontium; zirconium (D); and one or more calcium compounds (E) selected from calcium carbonate, calcium oxide and calcium hydroxide; wherein the ammonia decomposition catalyst comprises the cobalt (A), the rare earth element (B), the alkaline-earth metal element (C) and the zirconium (D) as metals or oxides.

Abstract: A high-efficiency visible-light catalytic material, a preparation method and an application thereof are provided by the present application, relating to the technical field of photocatalytic materials. The present application prepares photocatalytic material Ag@AgCl/CA by compounding Ag@AgCl and calcium alginate gel, and the prepared photocatalytic material is shaped as small particles. The photocatalytic material Ag@AgCl/CA is used to degrade tetracycline antibiotics.

Abstract: The invention provides a catalyst composition, including a mixture of catalytically active particles and a magnetic material, such as superparamagnetic iron oxide nanoparticles, capable of inductive heating in response to an applied alternating electromagnetic field. The catalytically active particles will typically include a base metal, platinum group metal, oxide of base metal or platinum group metal, or combination thereof, and will be adapted for use in various catalytic systems, such as diesel oxidation catalysts, catalyzed soot filters, lean NOx traps, selective catalytic reduction catalysts, ammonia oxidation catalysts, or three-way catalysts.

Abstract: The present invention relates to metal-organic frameworks (MOFs) which contain trimetallic centres with pyrazole as a ligand in the structure thereof. Particularly, it relates to MOFs which contain units of formula (I). The present invention also relates to a photocatalytic method for generating H2 starting from liquid water or vapour using said materials.

Abstract: The present invention relates to a device for heterogeneous plasmonic photocatalysis. The device comprises a crystalline or quasi-crystalline superstructure of plasmonic nanoparticles attached to a substrate, and a plurality of catalytically active nanoparticles embedded into the superstructure of plasmonic nanoparticles. Further, the invention relates to a method of manufacturing the device for heterogeneous plasmonic photocatalysis.

Abstract: A field of environmental protection and discloses a method for preparing an amorphous silica-alumina encapsulated metal oxide catalyst and application thereof. The catalyst is prepared by filling silica-alumina precursors in tunnels of a monometallic or bimetallic complex and then performing heat treatment. The catalyst has the advantages that acidic sites and oxygen vacancies are highly dispersed, the pore size range is large and the mass transfer efficiency is high, improves the efficiency of a cracking-oxidation tandem reaction, and achieves full purification of carbon/nitrogen pollutants in landfill leachate. The COD removal rate of the landfill leachate reaches 98.3% or above, and the ammonia nitrogen removal rate thereof reaches 98.0% or above. The COD concentration of oxypyrolysis purified effluent is less than 98.7 mg/L and the ammonia nitrogen concentration thereof is less than 24.9 mg/L.

Abstract: A process for regenerating catalyst from a fluidized catalytic process comprising is disclosed. The process comprises providing an oxygen stream and a preheated carbon dioxide recycle stream and mixing the oxygen stream and the preheated carbon dioxide recycle stream to provide a carbon dioxide rich oxidation stream. The carbon dioxide rich oxidation stream is passed to a regenerator unit to provide a carbon dioxide rich flue gas stream. One or more of a sulfur-containing compound, a nitrogen-containing compound, or both in the carbon dioxide rich flue gas stream is reacted with a reactant in a decontamination reactor to form a reactor effluent stream comprising reactant salt. The reactor effluent stream is filtered to remove the reactant salt and catalyst fines to produce a filtered reactor effluent stream. A carbon dioxide recycle stream is taken from the filtered reactor effluent stream.

Abstract: Provided herein are devices that facilitate the magnetic separation of an analyte from a sample, and methods of use thereof. In particular embodiments, devices and methods are provided for the trans-interfacial magnetic separation (TIMS) of analytes from a sample.

Abstract: This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting and analyzing blood cells in biological samples. A small measured quantity of a biological sample, such as whole blood, is placed in a mixing bowl on the disposable test cartridge after being inserted into the cell analyzer. The analyzer also deposits a known amount of diluent/stain in the mixing bowl and mixes it with the blood. The analyzer takes a measured amount of the mixture and dispenses in a sample cup on the cartridge in fluid communication with an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping as it is transferred into the imaging chamber by the analyzer. Images of all of the cellular components within the imaging chamber are counted and analyzed to obtain a complete blood count.

Abstract: A biological imaging analyzer comprises a flowcell configured to flow biological cells therethrough, the flowcell including an imaging region where images of the biological cells are captured. The analyzer also comprises a lighting module configured to generate a light, the lighting module comprising a light guide configured to convey the light to an imaging region of the flowcell. The analyzer further comprises an imaging module configured to capture images of the biological cells at the imaging region of the flowcell. The analyzer also comprises a flowcell holder in operable connection with the flowcell. A method of positioning a flowcell for biological analysis comprises providing the flowcell configured to flow a biological sample for analysis, and operably connecting the flowcell holder with the flowcell.

Abstract: Provided is a microfluidic detection device, including a base with a microfluidic channel structure formed on the base and a lid covering the base. The microfluidic channel structure includes a sample well for loading a sample, a detection well having a first reagent for reacting with the sample, and a channel connecting the sample well and the detection well. The detection well has a recess deeper than the channel, and the base includes a protrusion corresponding to the recess to form a space between the protrusion and the recess. Also provided is a method for rapid diagnostic testing by the microfluidic detection device.

Abstract: A micro-bioelectrochemical cell (?-BEC) device is disclosed that includes from 4 to 96 microfluidically connected chambers, in which each chamber encloses a volume of about 1 ?L to 2 ?L. A working electrode, reference electrode, and counting electrode contacts each volume. The ?-BEC device includes a support layer coated with a working electrode layer, a microfluidics layer containing a plurality of wells, and an electrical layer containing the reference and counter electrodes. Methods of using the ?-BEC device to perform bioelectrochemical measurements of cells are also disclosed.