Abstract: Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to methods including selectively neuromodulating afferent or efferent renal nerves. One or more measurable physiological parameters corresponding to systemic sympathetic overactivity or hyperactivity in the patient can thereby be reduced. Selectively neuromodulating afferent renal nerves can include inhibiting sympathetic neural activity in nerves proximate a renal pelvis. This can include, for example, neuromodulating via fluid within the renal pelvis. Selectively neuromodulating efferent renal nerves can include inhibiting sympathetic neural activity in nerves proximate a portion of a renal artery or a renal branch artery proximate a renal parenchyma. This can include, for example, neuromodulating via a therapeutic element within the portion of the renal artery or the renal branch artery.

Abstract: Apparatus and associated methods relate to controlling electrical power of an electrotherapeutic signal that is provided to a biological tissue engaged by an electrosurgical instrument during a medical procedure. Electrical power—a product of a voltage difference across and an electrical current conducted by the engaged biological tissue—is controlled according to a therapeutic schedule. The electrotherapeutic schedule can be reduced or terminated in response to a termination criterion being met. In some examples, the termination criterion is a current characteristic, such as, for example, a decrease in current conducted by the engaged biological tissue. In some examples, the termination criterion is a biological tissue resistance characteristic, such as, for example, an increase in the biological tissue resistance that exceeds a predetermined delta resistance value.

Abstract: A vitreous enamel coating for an electrosurgical metal cutting blade, in which incident light striking the vitreous enamel coating is diffusely reflected or absorbed, and the vitreous enamel coating exhibits a 60° gloss value less than 100 gloss units as measured according to ASTM D523-14, Standard Test Method for Specular Gloss. The coating reduces glare from light sources such as a nearby plasma-mediated discharge, operating theater lights or lights provided on an electrosurgery apparatus. The coating may also lessen interference with markers, sensors or other instruments designed to measure light emitted by or passing through nearby tissue such as by transillumination.

Abstract: Disclosed embodiments include apparatuses, systems, and methods for guiding a rotatable actuator along a helical path with a varied pitch to motivate an attached implement. In an illustrative embodiment, an apparatus includes an elongated implement movable along an axis and a rotatable actuator operably coupled with a proximal end of the implement to motivate the implement to move along the axis in response to rotation of the rotatable actuator. A guide is operably coupled with rotatable actuator, where the guide defines a generally helical channel around the axis to direct movement of a rotatable actuator, and wherein a pitch of the helical channel is varied to reduce a distance of travel of the actuator along the axis per unit of rotation of the actuator.

Abstract: The invention generally relates to systems and methods for improving sleep by treating at least one of rhinitis, congestion, and/or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, nasal congestion, coughing, sneezing, and nasal or throat irritation and itching.

Abstract: The present invention provides a catheter apparatus with a carrier comprising right-handed wire helixes and left-handed wire helixes that are plainly or bi-axially woven into a tubular structure. A therapeutic assembly wraps around one of the wire helixes to stabilize an associated interstice of the tubular structure. The regular shape of the carrier may be quickly recovered after the carrier is seriously bent or distorted in an intravascular treatment.

Abstract: A method, consisting of modeling physical parameters representative of a probe in proximity to body tissue during an ablation procedure performed by the probe. The method also includes measuring a subgroup of the physical parameters during a non-ablation stage of the ablation procedure so as to generate measured non-ablative values of the subgroup, and measuring the subgroup of the physical parameters during an ablation stage of the ablation procedure so as to generate measured ablative values of the subgroup. In response to the modeling, the method includes generating calculated non-ablative values of the subgroup for the non-ablation stage, and generating calculated ablative values of the subgroup for the ablation stage. The method compares the measured non-ablative values with the calculated non-ablative values, and compares the measured ablative values with the calculated ablative values, so as generate optimal values of the physical parameters.

Abstract: An ablation instrument (e.g., an ablation balloon catheter system) includes an elongate catheter having a housing with a window formed therein. An energy emitter is coupled to the elongate catheter and is configured to deliver ablative energy. A controller is received within the window and is coupled to the energy emitter such that axial movement of the controller within the window is translated to axial movement of the energy emitter and rotation of the controller within the window is translated into rotation of the energy emitter. The instrument includes a motor that is at least partially disposed within the housing of the catheter; a first gear that is operatively connected to and driven by the motor; and a second gear that is coupled to the energy emitter and is driven by the first gear to cause rotation of the energy emitter, while allowing the energy emitter to move axially.

Abstract: Embodiments of the invention include a compact, lightweight, hand-held laser treatment device that combines the emissions of two separate laser energy sources into a common optical pathway for improved therapeutic effect. In some embodiments, the device includes a housing having separate first and second laser sources disposed within the interior thereof. In some embodiments, the laser energy emissions from the two internal laser sources can be individually or concurrently transmitted to a delivery tip of the device via a laser transmission path also defined within the interior of the housing. In some embodiments, the structural and functional features of the first and second laser sources, in concert with the unique architecture of the laser transmission path, can be configured to provide efficacy and efficiency in the operation of the device within the spatial constraints of the lightweight, hand-held housing thereof.

Abstract: The present disclosure provides an adaptive optics system including at least one active pixel sensor array that detects light and sends a signal to a processor. The adaptive optics system also includes a wavefront correction system including at least one wavefront control structure and the processor, and that executes instructions on the processor to produce a digital image in which at least one wavefront distortion in the light detected by the active pixel sensor array is partially or fully corrected. The disclosure also provides methods of using the adaptive optics system.

Abstract: A method for administering a cone contrast color vision test includes displaying a first color at a first contrast level in a first region of a display and a second color at a first contrast level in a second region of the display, receiving a first input signal via an input device that indicates whether the patient recognizes the first region, displaying the first color at a second contrast level in a third region of the display and the second color at a second contrast level in a fourth region of the display, receiving a second input signal indicative of whether the patient recognizes the third region, assigning a score related to cone sensitivity of the first color at the first and second contrast levels, storing the score, and comparing the score to a previous score to calculate a progression of a cone sensitivity loss.

Abstract: A device and a method for determining an ocular aberration of at least one eye of a user are disclosed. The device contains a wavefront sensing unit for measuring at least one optical wavefront with at least one light beam, from which an ocular aberration of the at least one eye of the user is determined. The device further contains at least one diffractive element for generating multiple diffraction orders in the light beam in two meridians in a manner that the multiple diffraction orders are spatially separated on the wavefront sensing unit and in the eye of the user. The device and the method allow generating an ocular defocus map in a one-shot assessment in real-time, especially by employing an automated measurement of the ocular aberrations with regard to different eccentricities of the eye of the user in two meridians.

Abstract: Methods and systems for identifying CNV membranes and vasculature in images obtained using noninvasive imaging techniques are described. An example method includes generating, by a first model based on at least one image of a retina of a subject, a membrane mask indicating a location of a CNV membrane in the retina. The method further includes generating, by a second model based on the membrane mask and the at least one image, a vasculature mask of the retina of the subject, the vasculature mask indicating CNV vascularization in the retina.

Abstract: Provided are ophthalmologic image processing method, including an acquisition step of acquiring OCT data of an eye to be examined based on a spectral interference signal output from an OCT optical system, a setting step of setting a depth region including an image position of a tissue as an extraction region for data on one-direction side from a zero delay position in the OCT data, and a display control step of extracting extracted OCT data corresponding to the extraction region from the OCT data and displaying the extracted OCT data in a display region set in advance on a monitor, and an OCT apparatus that executes the method.

Abstract: System and method for enabling user communication with eye-based feedback. A selection interface selectively presents a series of communication options to the user. A sensor detects light reflected from the eye of the user and provides a correlative signal, which is processed to determine a relative eye orientation that includes the relative orientation of the pupil with respect to the head orientation of the user. The eye may be illuminated by a light source or ambient lighting. The sensor may detect infrared light reflected from the eye illuminated by an infrared light source. The relative eye orientation may be determined by processing images captured by an image sensor. The relative eye orientation may be determined by detecting an instantaneous relative orientation of the pupil or by detecting a transient change of the pupil. Based on the determined relative eye orientation, a selected communication option is determined and implemented.

Abstract: A visual function detection apparatus includes: a display controller configured to cause an image for determination to be displayed in a display region on a display screen of a display unit and move the image for determination within the display region; a gazing point detector configured to detect a position of a gazing point of a test subject observing the display screen; a relation detector configured to detect relation information among a position of the image for determination on the display screen, a moving direction of the image for determination, and a moving direction of the gazing point; and a visual function detector configured to detect a visual function of the test subject based on the relation information.

Abstract: Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including a head mounted display to monitor one or more physiologic signals from the face or head of the subject is disclosed. A method for analyzing an ocular parameter of the subject to determine a sympathetic and a parasympathetic outflow thereto is disclosed.

Abstract: A display system can include a head-mounted display configured to project light to an eye of a user to display virtual image content at different amounts of divergence and collimation. The display system can include an inward-facing imaging system images the user's eye and processing electronics that are in communication with the inward-facing imaging system and that are configured to obtain an estimate of a center of rotation of the user's eye. The display system may render virtual image content with a render camera positioned at the determined position of the center of rotation of said eye.

Abstract: A system for tracking a piece of medical equipment intraoperatively using a collinear array of fiducial markers positioned at known fixed distances relative to each other on the medical equipment and a camera capturing an image on a single image plane. Representations of the fiducial markers are segmented from a captured image, 3D orientation and position of the medical equipment are calculated using the segmented representations, and the orientation and position of the medical equipment are tracked relative to the camera. The orientation and position of the medical equipment may be registered within a 3D virtual space. The system may be used as part of a surgical navigation system.

Abstract: A method for determining a predicted lesion size formed in a tissue by receiving or calculating a measure of contact force between the electrode and the tissue, determining a tissue characterization, and calculating the predicted lesion size using both the measure of contact force and the tissue characterization. A system comprising an electronic control unit configured to receive or determine a measure of contact force between the electrode and the tissue, characterize the tissue based on both the measure of impedance and the measure of contact force, and cause the tissue characterization to be either (a) presented to a user, or (b) applied to calculate a metric and cause the metric to be presented to the user.

Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

Abstract: A system and method for deformation simulation of a hollow organ able to be deformed by the introduction of a medical instrument. The method includes provision of a pre-trained machine-learning algorithm, provision of a 3D medical recording of the hollow organ with surrounding tissue, with the 3D recording having been recorded before the introduction of a medical instrument, segmentation or provision of a segmentation of the 3D medical recording of the hollow organ and establishment or provision of a three-dimensional model of the hollow organ, provision of information about a medical instrument introduced or to be introduced, and simulation of the deformation of the hollow organ to be expected from introduction of the instrument on the basis of the segmented 3D medical recording of the hollow organ and of the surrounding tissue and of the information about the instrument by using the pre-trained machine-learning algorithm.

Abstract: A method comprises receiving a surgical instrument into engagement with a grip actuator of a teleoperational activation system. The surgical instrument includes movable jaws, and the surgical instrument is received in a prearranged gripping configuration with the jaws gripping a surgical accessory. The method includes generating a first control signal for manipulating the surgical instrument while maintaining the surgical instrument in the prearranged gripping configuration. The method further includes generating a second control signal for manipulating the surgical instrument to move from the prearranged gripping configuration to a second configuration.

Abstract: The subject matter includes a system and method for providing graphical feedback visualizing forces within a joint through a range of motion of the joint. The method can comprise receiving position data, receiving force data, and generating a graphical representation based on the position data and the force data. The receiving position data can include data for at least one bone of a joint while the at least one bone is moved through a range of motion (ROM). The receiving force data can occur concurrently to receiving the position data and using one or more processors, the force data can be collected from at least one force sensor embedded within a trial prosthesis in the joint. The graphical representation can illustrate changes in the force data versus locations of the bone as it moved through the ROM.

Abstract: Surgical robot for tracking and compensating bone movement, the robot comprising: a robot arm (3) and a tool guide (5) at the arm's end-effector, a tracker (1) attached to the robot arm at the same plane as the tool guide, the tracker comprising an assembly of articulated segments (1a-1d) and encoders (2) associated to the segments such that movement of the tracker is allowed and monitored in at least six degrees of freedom. The tracker base and the tool guide share the same frame, that is, are on the same plane, so that the system is able to determine directly the exact positioning of the tool guide with respect to the tracked bone without any intermediate device. This way, an optical tracker and the associated cameras can be dispensed with.

Abstract: A rollable digitizer device for collecting a plurality of points on a bone that includes a wheel having multiple probes emanating circumferentially therefrom. One or more contact sensors adapted to detect if at least one of probes is in contact with the bone. The contact sensors located in the wheel, on the wheel, proximal to said one or more contact sensors, or a combination thereof. A handle connected to the wheel and adapted to permit a user to roll the probes along the bone, so each of the probes make sequential and detectable contact with the bone to facilitate the collection of multiple points on the bone. A method for collecting a multiple registration points on a bone with the rollable digitizer device includes wielding the rollable digitizer by the handle. The probes are rolled along the surface of the bone to collect the plurality of registration points.

Abstract: A surgical instrument comprises a first member including a drive engageable with a first mating surface of a bone fastener. A second member is rotatable relative to the first member and includes an engagement element connectable with a second mating surface of the bone fastener. A part is disposed with the first member and being alternately connectable with an actuator and an adaptor attachable with an image guide. Systems, surgical adaptors, spinal implants and methods are disclosed.

Abstract: The present disclosure provides a system and method for using widely available ultrasound imaging to overcome the limitations of imaging guidewires and other small objects that may be subwavelength in size relative to an ultrasound wavelength. The system and method can reduce the use of X-rays and exposure to the dangerous effects of radiation and avoids the expense of MRI technology. The subwavelength object, such as a guidewire, can be detected using several methods and associated systems described herein, including the object changing positions at a frequency that creates a brighter ultrasound image of the object as the object progresses across a scanned region of the ultrasound detector. In some embodiments, the movement of the small object causes a different speckle signature than the object itself would otherwise generate. Analysis of changes in speckle patterns due to progressive movement of an object can yield a detectable object.

Abstract: A magnetic tracking device includes a sensor configured to generate a sensor electromotive force (EMF). The device includes a mechanism configured to select between a first operating mode in which the sensor generates the sensor EMF when receiving the magnetic field and a second operating mode in which the sensor generates a reduced amount of the sensor EMF when receiving the magnetic field. An interconnecting circuit generates a parasitic EMF in each of the first operating mode and the second operating mode. The interconnecting circuit connects to a processing device which receives a first measurement for the first operating mode, the first measurement representing the sensor EMF and the parasitic EMF, receives a second measurement for the second operating mode, the second measurement representing the parasitic EMF, compares the first measurement and the second measurement, and determines an approximate value of the sensor EMF.

Abstract: A tracker, a surgical navigation system with the tracker, and a method of operating the tracker are described. The tracker comprises a first switch configured to be operated between a first switch configuration and a second switch configuration. The tracker also comprises one or more sources of electromagnetic radiation configured to selectively emit electromagnetic radiation with a first radiation characteristic or a second radiation characteristic. The tracker further comprises electrical circuitry configured to selectively control the one or more sources of electromagnetic radiation to emit electromagnetic radiation having the first radiation characteristic in the first switch configuration and to emit electromagnetic radiation having the second radiation characteristic in the second switch configuration, wherein the second radiation characteristic is different from the first radiation characteristic.

Abstract: A surgical system includes a camera tracking system that determines a first pose transform between a first object coordinate system and the first tracking camera coordinate system based on first object tracking information from the first tracking camera which indicates pose of the first object. The camera tracking system determines a second pose transform between the first object coordinate system and the second tracking camera coordinate system based on first object tracking information from the second tracking camera indicating pose of the first object, and determines a third pose transform between a second object coordinate system and the second tracking camera coordinate system based on second object tracking information from the second tracking camera indicating pose of the second object. The camera tracking system determines a fourth pose transform between the second object coordinate system and the first tracking camera coordinate system.

Abstract: A surgical navigation system may include a processor and a display. The processor may receive a patient image and sensor data captured by a sensor, receive a medical image, generate a hologram of the medical image, perform coregistration between the patient image and the hologram, superimpose the hologram on the patient image, and display the superimposed image. Coregistration may be performed manually via a user interaction, or automatically based on one or more fiducials in the medical image and sensor data related to the fiducials. The system may monitor a change in the environment and update the display correspondingly. For example, the system may monitor a movement of a body of the patient, monitor the size of an organ of the patient as the organ is being under operation, or a movement of the surgical instrument. The sensor may be an augmented reality (AR) sensor in an AR device.

Abstract: A sequence of input samples that are measures of position or orientation of an input device being held by a user are received. A current output sample of a state of linear quadratic estimator, LQE, is computed that is an estimate of the position or orientation of the input device. The current output sample is computed based on i) a previously computed output sample, and ii) a velocity term. An updated output sample of the state of the LQE is computed, based on i) a previously computed output sample, and ii) a new input sample. Other embodiments are also described and claimed.

Abstract: Provided is a medical observation system that includes a first medical signal processing device including a first signal processing unit that acquires first image data corresponding to a result of image capturing of an affected part by a medical observation device and provides first signal processing to the first image data, and a second medical signal processing device including a second signal processing unit that acquires second image data corresponding to the result of image capturing from the first medical signal processing device through a predetermined network and provides second signal processing to the second image data. The second signal processing unit transmits information related to the second signal processing to the first medical signal processing device. The first signal processing unit controls the first signal processing based on the second signal processing.

Abstract: A robotic catheter system includes a controller with a master input device. An instrument driver is in communication with the controller and has a guide instrument interface including a plurality of guide instrument drive elements responsive to control signals generated, at least in part, by the master input device. An elongate guide instrument has a base, distal end, and a working lumen, wherein the guide instrument base is operatively coupled to the guide instrument interface. The guide instrument includes a plurality of guide instrument control elements operatively coupled to respective guide drive elements and secured to the distal end of the guide instrument. The guide instrument control elements are axially moveable relative to the guide instrument such that movement of the guide instrument distal end may be controlled by the master input device.

Abstract: Methods and devices are provided for robotic surgery, and in particular for controlling various motions of a tool based on visual indicators. In general, a surgical tool can include an elongate shaft and an end effector coupled to a distal end of the elongate shaft and including first and second jaws. The tool can have at least one visual indicator disposed thereon and configured to indicate a size, position, or speed of movement of the tool or components of the tool.

Abstract: A surgical drape assembly can include a surgical drape; and a cinch assembly affixed to the surgical drape. The cinch assembly can include a folding mechanism having a plurality of links and at least two hinge joints respectively connecting respective adjacent links of the plurality of links. The plurality of links can be foldable relative to one another about the at least two hinge joints between an unfolded configuration and a folded configuration. A first portion of the surgical drape is in an extended configuration in the unfolded configuration with a portion of the drape being in a gathered configuration in the folded configuration of the plurality of links.

Abstract: A disposable cover for PEMFT medical devices and a method of making and using the same. The disposable cover is made from a fluidproof material that protects the user and the medical device by being a barrier therebetween. The disposable cover can be adapted for strap-based medical devices and disc-based medical devices, as well as other devices.

Abstract: Provided is a microscope drape capable of further facilitating an attachment operation thereof to a surgical microscope. A microscope drape comprises: a lens cap attached to and detached from a housing of an objective lens of a surgical microscope; a protective lens protecting the objective lens; and a drape main body covering the surgical microscope. The lens cap is formed such that a portion in a circumferential direction of a cylinder is opened, and has an arc-shaped cross section perpendicular to an optical axis of the objective lens. The microscope drape includes: a protective lens holder that is a cylinder whose outside diameter is larger in size than an inside diameter of the lens cap in a natural state and holds the protective lens; and a joint that pivotably supports the protective lens holder with respect to the lens cap around a pivot axis perpendicular to the optical axis.

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

Abstract: In a method for synchronous magnetic resonance (MR) imaging and radiation therapy using a combined system having a radiation apparatus and an MR imaging apparatus, wherein the system is designed to record MR signals of a subject during irradiation of the subject, a three-dimensional MR volume data set of the subject is acquired that contains a target volume for the irradiation, the location of a central beam of the radiation therapy apparatus relative to the subject, is continuously determined, and a second MR image data set is determined, which is positioned essentially perpendicular to the central beam. If the location of the central beam changes, a correspondingly changed second MR image data set is determined perpendicular to the central beam.

Abstract: A method for performing remote tissue assessment of a tissue region includes selecting imaging parameters, obtaining M image datasets of the tissue region when the tissue region is illuminated by a light signal having a unique discrete wavelength, obtaining a reference image dataset of the tissue region without illumination, processing the M+1 image datasets to obtain M marker maps where each marker map corresponds to a different physiological marker, and analyzing at least one of the marker maps to determine whether a physiological condition exists at the tissue region or to monitor the status of an existing physiological condition at the tissue region. In one or more embodiments, the method may be performed by a portable light source unit including a housing configured for use with a mobile device having a camera, or by a system including a light source unit, an optical sensor module, and a mobile device.

Abstract: An optical physiological finger sensor system including an ergonomic interface shaped into a natural curve of a user's hand and finger.

Abstract: A detecting device includes a semiconductor substrate, a first light-emitting section provided in a layered manner at the semiconductor substrate and configured to emit first light having a first wavelength band toward a living body, a second light-emitting section provided at the semiconductor substrate in a layered manner and configured to emit second light having a second wavelength band toward the living body, a first light-receiving section provided at the semiconductor substrate and configured to receive light from the living body based on the first light, a second light-receiving section provided at the semiconductor substrate and configured to receive light from the living body based on the second light, and an optical filter provided at the first light-receiving section and configured to transmit light having the first wavelength band and to attenuate light having the second wavelength band. The second wavelength band is longer than the first wavelength band.

Abstract: A fiber optic force sensing assembly for detecting forces imparted at a distal end of a catheter assembly. The structural member may include segments adjacent each other in a serial arrangement, with gaps located between adjacent segments that are bridged by flexures. Fiber optics are coupled to the structural member. In one embodiment, each fiber optic has a distal end disposed adjacent one of the gaps and oriented for emission of light onto and for collection of light reflected from a segment adjacent the gap. The optical fibers cooperate with the deformable structure to provide a change in the intensity of the reflected light, or alternatively to provide a variable gap interferometer for sensing deformation of the structural member. In another embodiment, the gaps are bridged by fiber Bragg gratings that reflect light back through the fiber optic at central wavelengths that vary with the strain imposed on the grating.

Abstract: A system for the optical measurement of pH includes a light emitter to emit an excitation light, and a detector coupled to receive florescence light produced by a compound in a mouth of a patient in response to the excitation light. A controller is coupled to the detector, and the controller includes logic that when executed by the controller, causes the system to perform operations. The operations may include emitting the excitation light from the light emitter; measuring an intensity of the florescence light emitted from a surface of individual teeth in a plurality of teeth in the mouth; and determining, based on the intensity of the florescence light, one or more locations on the individual teeth likely to develop demineralization.

Abstract: An in-vivo temperature measurement device includes a plurality of thermal resistors, temperature sensors for measuring an epidermis temperature of a living body, and temperature sensors for measuring an upper surface temperature that are provided at both ends of the thermal resistors, respectively, a memory that stores an estimation model of the core temperature of the living body that takes into consideration a non-thermal equilibrium state of the living body, and thermal resistance values of the thermal resistors, and an arithmetic circuit that estimates, based on the plurality of temperatures measured by the temperature sensors and the temperature sensors, the core temperature of the living body using the estimation model and the thermal resistance values, and the thermal resistance values are different from one another.

Abstract: Embodiments of the present technology may include a system for monitoring a physiological parameter in a person, the system including a frequency synthesizer configured to generate radio waves across a range of radio frequencies. Embodiments may also include at least one transmit antenna configured to transmit the radio waves below the skin surface of a person. Embodiments may also include a two-dimensional array of receive antennas configured to receive radio waves, the received radio waves including a reflected portion of the transmitted radio waves. Embodiments may also include processing circuits configured to generate data in response to the received radio waves and to coherently combine the generated data across the two-dimensional array of receive antennas and across the range of radio frequencies to produce a pulse wave signal of the person.

Abstract: The present invention provides a personalized, three-dimensional printed, human auricle-specific multiple auricular points' bio-signal acquisition, health status monitoring, and bio-stimulation device, including an artificial ear model made of at least one bio-compatible, flexible polymer, a plurality of sensing and stimulating electrodes with at least one sensing end and a signal acquisition/processing end penetrating through a body of the ear mold conformably with a human auricle so that a surface of the ear mold where sensing end of the electrodes is disposed creates an electrode-human skin interface for bio-signal detection and bio-stimulation responsive thereto. Methods of fabricating the device based on 3-D printing, 3D scanning and modelling techniques and using thereof for bio-signal acquisition, analysis, health status monitoring and bio-stimulation are also provided.

Abstract: The present disclosure is directed to apparatuses, systems and methods for measuring time-varying radar cross section (RCS) of an artery of a patient, which may be used to determine blood pressure of a patient. In some embodiments, an apparatus is provided which comprises a radio-frequency (RF) transceiver for generating RF waves, and at least one sensor configured for positioning on or adjacent the skin of a patient, and at least one of transmitting the RF waves into tissue of the patient and receiving RF wave reflections from at least one artery located within the tissue. The apparatus may further comprise a processor having computer instructions operating thereon configured to cause the processor to determine an RF arterial pulse waveform based on the received RF wave reflections. The time-varying radar cross section (RCS) comprises the RF arterial pulse waveform. This may be in turn correlated to blood pressure of the patient.