Abstract: An illustrative optical measurement system includes a light source configured to emit light directed at a target. The optical measurement system further includes a photodetector configured to detect a photon of the light after the light is scattered by the target. The optical measurement system further includes a control circuit configured to receive a first input voltage that is a temperature-dependent voltage. The control circuit is further configured to receive a second input voltage that is a temperature-invariant voltage. The control circuit is further configured to output, based on a combination of the first input voltage and the second input voltage, a bias voltage for the photodetector, wherein the combination of the first and second input voltages is configured to cause the bias voltage to vary based on temperature.

Abstract: A system for the imaging and analysis of human lesions having an illumination component, an imaging sensor, a tunable liquid imaging lens, and driver controlling different focal length settings of the electrically tunable liquid imaging lens. An enclosure houses the tunable liquid imaging lens, the illumination component, and the imaging sensor. The tunable liquid imaging lens has either a bendable lens membrane allowing the focal length to be controlled by fluid pressure, or the tunable liquid imaging lens includes two transparent liquids that are placed between two electrodes to control the focal length. An imaging sensor captures lesion images within a fraction of a second from each other across a range of focus settings to produce a single, sharp, all-focus image.

Abstract: An estimator estimates the body temperature of a subject from the temperatures of the inner corners of the eyes in the temperature information obtained from a measurement result of an infrared sensor. The infrared sensor two-dimensionally measures the distribution of infrared rays radiated from the surface of the face of the subject including the inner corners of the eyes of the subject, and the estimator obtains a temperature distribution from the data of the distribution of the light intensity of the infrared rays and identifies the inner corners of the eyes from the obtained temperature distribution to estimate the temperatures of the identified inner corners of the eyes as the body temperature. A corrector corrects the body temperature estimated by the estimator by the difference between the temperatures of the inner corners of the left and right eyes in the measurement result of the infrared sensor.

Abstract: A method of determining blood vessel stiffness including, acquiring a plurality of images of a portion of a blood vessel, analyzing the plurality of images to determine a maximum diameter of the portion of the blood vessel at a plurality of points along the blood vessel, analyzing the plurality of images to determine a minimum diameter of the portion of the blood vessel at the plurality of points along the blood vessel, determining a blood pressure experienced in the portion of the blood vessel, and calculating a stiffness of the portion of the blood vessel based on a ratio of the blood pressure and a difference in a diameter of the blood vessel at one or more of the plurality of points along the blood vessel.

Abstract: An electronic device, and a biological detection control method and apparatus. The electronic device includes: a packaging layer, on which a light-transmitting part is provided; a fingerprint identification unit and a pulse wave detection unit disposed within the packaging layer; and a substrate, the fingerprint identification unit and the pulse wave detection unit being disposed on the substrate and fixedly connected to the substrate, where the pulse wave detection unit directly faces the light-transmitting part.

Abstract: A biological information measurement device includes a blood pressure measurement unit including a blood pressure measurement control unit configured to control a cuff configured to compress a target measurement site of a subject, a pump configured to supply gas into the cuff, an exhaust valve configured to adjust exhaust of the gas from the cuff, and a pressure detection unit configured to detect a cuff pressure that is a pressure in the cuff, the blood pressure measurement unit being configured to measure a blood pressure of the subject, and an electrocardiographic measurement unit including an electrode provided on a target measurement site side of the cuff and configured to measure an electrocardiographic waveform by processing an electrical signal obtained through a plurality of electrodes that can come into contact with a skin of the subject.

Abstract: A biometric information measuring device includes a blood pressure measurement unit including a cuff configured to compress a target measurement site of a subject, a pump configured to supply a gas into the cuff, an exhaust valve configured to adjust discharge of the gas from within the cuff, a pressure detection unit configured to detect a cuff pressure that is a pressure in the cuff, a cuff pressure control unit configured to control the pump and the exhaust valve, and a blood pressure calculation unit configured to calculate a blood pressure of the subject, the blood pressure measurement unit being configured to measure the blood pressure of the subject, an electrocardiographic measurement unit being configured to process an electrical signal acquired through a plurality of electrodes contactable to a skin of the subject to measure an electrocardiographic waveform.

Abstract: Various embodiments provide a wellness tracking device with a base plate that may be utilized as a combination electrode by a variety of sensors. The base plate may be a multi-material electrode that includes a conductor and a transparent or semi-transparent material to enable optical sensing. In certain embodiments, the base plate supports a plurality of different sensors, which may selectively utilize the base plate as an electrode.

Abstract: A pulse wave generation apparatus includes a pressure sensor sensing an external pressure, an optical adjustment unit configured to change a transmissivity of light, a reflection unit reflecting the light, and a control unit outputting an optical adjustment signal for changing the transmissivity based on a pressure measurement value received from the pressure sensor to the optical adjustment unit.

Abstract: A biological information measuring apparatus (10) includes a compression belt (20) to be wound around a part of a living body, a pressure adjusting unit (51) configured to change an internal pressure of the compression belt, a data acquiring unit (52) configured to acquire time-series data indicating a change in each of the internal pressure of the compression belt and a capacity of the compression belt in a period in which the internal pressure of the compression belt is changing, and a tonus-information calculating unit (53) configured to calculate, based on the time-series data, tonus information indicating a correspondence relation between a first indicator indicating pressure applied to a blood vessel wall (100) of the living body and a second indicator indicating a capacity on an inner side of the blood vessel wall.

Abstract: The invention relates to a method for determining an arterial pressure of a user, by measuring a physiological parameter, the physiological parameter passing through an extremum when the transmural pressure of the artery is zero, the method comprising: a) applying a pressure to the artery, so as to modify the transmural pressure of the artery; b) measuring the physiological parameter of the user by means of a sensor; c) establishing a calibration function, the calibration function defining a relationship between the transmural pressure and the parameter; d) applying a pressure to the artery at a measurement time, and measuring the physiological parameter at the measurement time; e) estimating a transmural pressure at the measurement time; f) based on the transmural pressure estimated in step e) and on the pressure applied at the measurement time, estimating an arterial pressure of the user.

Abstract: Systems and methods are provided for operating a physiological monitoring system that comprises a distributed algorithm. The physiological monitoring system may comprise a sensor and a physiological monitor that may be communicatively coupled with the sensor. The sensor may store algorithm configuration data; and the physiological monitor may store an executable code segment configured to execute a first algorithm. The physiological monitor may be configured to receive the algorithm configuration data and to configure or modify at least part of the first algorithm based upon the algorithm configuration data to determine at least one physiological parameter of a subject based on physiological signal provided by the sensor.

Abstract: The present invention relates to a device (100), systems (500, 500?, 500?) and a method for providing imaging of one or more aspects of blood perfusion induced by cardiac induced blood motion in a skin region (12) of a subject. Current perfusion imaging systems use either photoplethysmography (PPG) or speckle contrast (SC), but a problem of both techniques is that considerable ambiguity exists because the source of the signal (volume pulsatility in PPG or blood flow in SC) is unknown. The present invention is based on the idea of combining two different types of measurement, namely widefield imaging and radial imaging, in order to estimate the source depth (20) of the signal to provide more accurate PPG imaging and SC imaging.

Abstract: A catheter and introducer sheath assembly is provided for measuring a flow rate in a conduit by dilution methods. The catheter is configured to engage the introducer sheath in a predetermined alignment, where an indicator is passed through a volume defined by an exterior of the catheter and an interior of the introducer sheath to be introduced into the flow to be measured. The determination of the indicator temperature is extrapolated or estimated from (i) an observed temperature curve of an indicator sensor on the catheter that records a substitution of warmed fluid in the sheath by the introduced indicator and (ii) a pre-examined, predetermined or identified thermal properties or characteristics of the sensor, the catheter, or the sensor and catheter. The determination of the flow rate in the conduit is estimated using (i) the area of the dilution bolus and (ii) the return to baseline of the dilution bolus.

Abstract: A catheter and introducer sheath assembly is provided for measuring a flow rate in a conduit by dilution methods. The catheter is configured to engage the introducer sheath in a predetermined alignment, where an indicator is passed through a volume defined by an exterior of the catheter and an interior of the introducer sheath to be introduced into the flow to be measured. The determination of the indicator temperature is extrapolated or estimated from (i) an observed temperature curve of an indicator sensor on the catheter that records a substitution of warmed fluid in the sheath by the introduced indicator and (ii) a pre-examined, predetermined or identified thermal properties or characteristics of the sensor, the catheter, or the sensor and catheter. The determination of the flow rate in the conduit is estimated using (i) the area of the dilution bolus and (ii) the return to baseline of the dilution bolus.

Abstract: A method for assessing and/or reducing artifacts arising from reconstruction of magnetic particle imaging (MPI) total image data set (c(r)) from MPI signal data (s(f), u(t)) using an appended system matrix (SM_AB) comprises: a) reconstructing signal data (s(f), u(t)) using appended system matrix (SM_AB) derived from at least two system matrices (SM_A, SM_B) for generating input image data (cin(r)); b) selecting at least one voxel as selected voxel from the input image data (cin(r)) for generating output image data (cout(r)); c) determining eigen-reconstruction signal data sen(f) by selecting one or more line entries of the appended system matrix (SM_AB) that correspond to the selected voxel(s); d) reconstructing eigen-reconstruction signal data se(f) using the appended system matrix (SM_AB) for generating eigen-reconstruction image data ce(r); and e) subtracting the eigen-reconstruction image data ce(r) or weighted eigen-reconstruction image data ce?(r) from the input image data cin(r) for generating updat

Abstract: A system for performing at least one impedance measurement on a biological subject, the system including a measuring device having a first housing including spaced pairs of foot drive and sense electrodes provided in electrical contact with feet of the subject in use, a second housing including spaced pairs of hand drive and sense electrodes provided in electrical contact with hands of the subject in use, at least one signal generator electrically connected to at least one of the drive electrodes to apply a drive signal to the subject, at least one sensor electrically connected to at least one of the sense electrodes to measure a response signal in the subject and a measuring device processor that at least in part controls the at least one signal generator, receives an indication of a measured response signal from the at least one sensor and generates measurement data indicative of at least one measured impedance value and a client device in communication with the measuring device, the client device being ada

Abstract: The present disclosure provides a target identification method, a target identification device, an electronic apparatus, a storage medium and a neuromodulation apparatus. The target identification method includes: acquiring scan data of a subject, the scan data including data obtained from magnetic resonance imaging of the subject's brain; determining the corresponding relationship of regions of interest of a disease type of the subject according to the disease type of the subject; determining at least one disease region of interest and at least one target region of interest of the subject in the scan data according to the corresponding relationship of the regions of interest; determining connectivity between each of voxels in the target region of interest and each disease region of interest in the at least one disease region of interest; and determining the positions of the voxels with the connectivity meeting a preset target connectivity condition in the target region of interest as the targets.

Abstract: A wearable device for monitoring respiratory function includes a front portion having embedded fiber Bragg gratings (FBGs). The device includes at least one light emitter, each light emitter configured to pulse light waves through a corresponding FBGs. The device further includes at least one light sensor configured to receive pulsed light waves. A processor receives from the light sensors peak wavelengths reflected by the at least one FBG and detects effective shifts of the Bragg wavelengths of the at least one FBG caused by body deformation over a period of time to establish a baseline respiratory pattern, the device may compare the baseline respiratory pattern with profiled respiratory patterns to determine whether the baseline respiratory pattern is indicative of a potential disease state and provide an alert of the potential disease state.

Abstract: An athletic performance analysis device. The device includes a chemically functionalized single wall carbon nanotube sensor array for the discrimination and quantification of volatile organic compounds (VOC's) or chemical biomarkers in human body fluids, a plurality of biometric sensors to gather data on physical characteristics of body function, and artificial intelligence machine learning models to process the collected sensor data for the purpose of rendering a comprehensive assessment of the functionality and performance readiness of an athletes body. The system further comprises a remote user interface, a communication interface arranged to send the collected breath biomarker and biometric data, a storage module arranged to store the received measurements, and a display arranged to display information to the user based on the compiled machine learning model analysis.

Abstract: There is provided a device for measuring a person's ventilation or metabolism metrics. The device includes a conduit shaped to receive an exhalation of air therethrough. The device includes at least one gas sensor passively sampling said exhalation of air by means of a positive or negative pressure differential. The device includes a pump configured to assist in said passive sampling. The pump is configured to adjust the flow rate of a sample portion of said exhalation of air passing through to the at least one gas sensor, so as to be proportional or linear within a predetermined threshold, to the flow rate of the exhalation of air passing through the conduit. The device is configured to operate via both breath-mixing and breath-by-breath modes using a single flow path. The device is configured to change between the breath-mixing and breath-by-breath modes as a function of operation of the pump.

Abstract: The present application relates to a method, apparatus and system for recognizing a tremor symptom, a recognition terminal and a storage medium. The method includes: receiving an image to be recognized which is uploaded by a user terminal, where the image to be recognized includes spiral graph used for recognizing whether a drawing person has a tremor state or not and evaluating a tremor level; and taking the image to be recognized as an input value of a pre-trained convolutional neural network regression device to obtain a tremor level. By using the method, the tremor can be recognized by means of images, which is non-invasive and patient-friendly, and since a model is a deep learning algorithm trained on a large spiral image dataset, results of evaluating the severity of essential tremor are accurate and consistent.

Abstract: The present invention relates to systems and methods for self-learning of locomotion characteristic and speed during bipedal locomotion using sensor and GPS technology.

Abstract: An apparatus for sensing motion of a subject's head comprises three conductive threads, each of which has a resistance that varies in response to strain thereof, circuitry for applying a voltage across the threads, circuitry for detecting current flowing through the threads, a data-collection system configured to detect the current, and a data-processing system that classifies, based on data provided by the data-collection system, a type of motion of the head and an extent of the motion.

Abstract: A system comprising a body wearable unit, with one or more cameras, a control system, and an electrical power source and a method for generating wearer data using the system, wherein the method comprises monitoring with one or more cameras a user wearing the wearable unit and providing a related camera signal; generating wearer data based on the related camera signal, wherein the wearer data comprise one or more of (i) wearer posture related data and (ii) wearer movement related data.

Abstract: A textile computing platform and method of operating the same. The platform includes at least one textile and at least one computing node including a sensory device positioned at the at least one textile. The platform includes a gateway device coupled to the computing node. The gateway device may be configured to: transmit, via a textile communication network, a discovery signal and a network time protocol signal; receive node discovery data from computing nodes to enumerate a subset of computing nodes for a current textile system state; generate physiological analytics based on a series of sensory data records received from the enumerated subset of computing nodes, the respective sensory data records associated with a time-stamp based on the network time protocol signal; and transmit actuating signals to the one or more enumerated subset of computing nodes for generating feedback to a user on a substantially real time basis.

Abstract: A system and method for monitoring pH of an intraoral device involves receiving the oral pH data from at least one pH sensor embedded within the intraoral device. The oral pH data is then correlated with one or more user related data to classify the oral pH data into one or more pre-defined categories indicative of a health condition. Further, the machine learning module generates feedback and/or recommendations for the user based on the classification of the oral pH data into one or more pre-defined categories. The oral pH data and/or feedback and/or recommendations are then communicated to the user and/or external device.

Abstract: The PPG based NIBG neural network prediction system of the present invention comprises a neural network configured to predict BG level of a subject based on PPG signal obtained from the subject wherein the subject is not undergoing medical treatment and the neural network is trained using training data from subjects not undergoing medical treatment. In another embodiment, the PPG based NIBG neural network prediction system of the present invention predicts BG level of a subject based on HbA1c of the subject measured using conventional finger prick method as well as PPG signal obtained from the subject wherein the subject is not undergoing medical treatment and the neural network is trained using training data from subjects not undergoing medical treatment.

Abstract: The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid.

Abstract: In one example aspect, a system is disclosed that includes an image capture device; a capillaroscope attachable to the image capture device, the capillaroscope including: a light source configured to provide offset light at an angle and location offset from a center horizontal axis and produce oblique remitted light off a patient site; a reverse lens through which the oblique remitted light passes therethrough; and one or more telescopic lenses through which the remitted light passes therethrough to a lens of the image capture device after passing through the reverse lens.

Abstract: An electronic device includes an output device, a biometric sensor including a light-emitting unit for emitting light at a first portion of a subject, and a light-receiving unit for receiving light emitted by the light-emitting unit and a processor operatively connected to the output device and the biometric sensor, wherein the processor can be configured to acquire a perfusion index on the basis of a photoplethysmogram (PPG) signal acquired through the biometric sensor, measure oxygen saturation by using the PPG signal if the perfusion index corresponds to a first criterion, and output, through the output device, guide information instructing an occlusion operation for a second portion, differing from the first portion of the subject, if the perfusion index corresponds to a second criterion.

Abstract: The present invention refers to a device (1) and a method of measuring a parameter of blood, preferably correlated to the presence or concentration of oxygen in blood. The invention provides to: excite a photosensitive element (18?) in contact with blood by excitation pulses, detect light responses of the photosensitive element corresponding to the excitation pulses, and analyze the plurality of luminescence decay curves at least two time windows (t1-tN). Moreover, the invention provides to: detect one or more light answer analog information regarding the luminescence curve decay at each time window, convert the analog information into digital data, process the digital data and the actual temperature value of blood by taking into account a plurality of data of previous measures of the parameter of blood performed during a previous training, and determine, as a result of the processing step, at least one value of said parameter of blood.

Abstract: The invention discloses a compact implantable biosensor assembly and a biological information monitoring device containing the assembly. The lower part of the implanted sensing section and of the needled for implantation are sealed in a closed space formed by the barrier, the lower part of the enclosure and the lower part of the needle aid. The horizontal connection section of the implantable sensing electrode is embedded in the enclosure. The export electrode is used to connect with a transmitter. The implantable biosensor assembly is directly connected with the circuit board of the transmitter through the export electrode, whereby the structure is compact.

Abstract: A virtual block test design for psychology testing includes a computer system with a processor, a memory, a client input device, and a client display screen. The memory is configured to store a plurality of virtual block tests via the processor. The client display screen is configured to display a specified virtual block test from the plurality of virtual block tests via the processor. The client input device is configured to manipulate the specified virtual block test displayed on the client display screen via the processor. Wherein, the computer system is configured to allow a client to take the specified virtual block test displayed on the client display screen by utilizing the client input device to manipulate the specified virtual block test.

Abstract: A computer-implemented method for conducting a polygraph test, the method comprising: monitoring physiological indices of a user during the steps of: providing the user with a plurality of pre-questions; and receiving answers from the user to the plurality of pre-questions; analyzing the answers to the pre-questions and physiological indices using machine learning and setting baselines for the monitored physiological indices; generating a plurality of test questions for the user based on the analysis; monitoring physiological indices of a user during the steps of: providing the user with the plurality of test questions; and receiving answers from the user to the test questions; comparing the baselines and the monitored physiological indices during the provision of answers to the test questions; and generating a test result to the test question.

Abstract: Systems and methods may provide assessment tools such as assessment prompts, to solicit feedback from patients at regular intervals, track patient progress, and recommend VR activities. A VR therapy platform may use a VR assessment to request patient feedback related to conditions such as anxiety, depression, and/or pain. Based on patient-provided assessment responses, a VR therapy platform may categorize the patient responses and recommend one or more appropriate VR activities to help reduce the intensity of the patient's reported state(s). In some embodiments, VR activity recommendations may be based on patient-reported feedback and biometric measurements. In some embodiments, a VR therapy platform may compare a patient's assessment responses with biometric measurements taken at or around the same time, along with a patient's health history, to determine whether patient responses may be contradictory or biased, and thus potentially requiring adjustment prior to recommending VR activities.

Abstract: The present invention relates to a stress detection system, device and method for detecting mental stress of a person. The system (1, 2) comprises an activity sensor (20) configured to acquire activity information related to activity of the person, a heart rate sensor (30) configured to acquire heart rate information indicating or allowing to compute the current heart rate of the person, and a stress detection device (10, 40, 60) for detecting mental stress of a person based on the acquired activity information and the acquired heart rate information. Hereby, posture changes of the person are taken into account to adapt a computed basal heart rate component and/or the computation of the basal heart rate component if a posture change is detected.

Abstract: An emotion estimation apparatus includes preparation biological information acquisition circuitry acquires, separately from subjects who are in a preparation space, first biological information indicating a physical state of each subject and analyzes the first biological information, preparation emotion information acquisition circuitry acquires emotion information indicating an emotion of each of the subjects, association construction circuitry constructs association information in which the first biological information and the emotion information corresponding to the first biological information are associated with each other, estimation biological information acquisition circuitry acquires second biological information indicating a physical state of any one subject of the subjects who is present in an estimation space, estimation circuitry extracts the emotion information associated in the association information with the first biological information that is equal to the second biological information, and

Abstract: Methods, systems, and devices for prenatal, perinatal, or postnatal mental or emotional distress identification and prediction are described. A system may be configured to receive physiological data associated with a user that is experiencing a prenatal, perinatal, or postnatal period of pregnancy and collected over a plurality of days, where the physiological data includes at least temperature data. Additionally, the system may be configured to determine a time series of temperature values. The system may then identify that the temperature values deviate from a prenatal, perinatal, or postnatal baseline of temperature values for the user and detect an indication of one or more conditions of mental or emotional distress experienced during the prenatal, perinatal, or postnatal period. The system may generate a message for display on a graphical user interface on a user device that indicates the indication of the one or more conditions of mental or emotional distress.

Abstract: An ADHD severity evaluation system using correlations between data gathered by VR and an ADHD-RS is provided. The ADHD severity evaluation system allows for gathering accurate data on a subject in an isolated and controlled environment by using VR, and improves the accuracy of ADHD diagnosis by measuring the severity and progression of ADHD. This can help determine an appropriate method and procedure for treating and/or relieving ADHD.

Abstract: The present invention is a bio-electrode composition containing an ionic polymer material as a component (A), where the component (A) includes a polymer having: a repeating unit-a having a structure selected from the group consisting of salts of ammonium, sodium, potassium, and silver formed with any of fluorosulfonic acid, fluorosulfonimide, and N-carbonyl-fluorosulfonamide; and a repeating unit-b having a nitro group. This provides: a bio-electrode composition capable of forming a living body contact layer for a bio-electrode that is excellent in electric conductivity and biocompatibility, is light-weight, can be manufactured at low cost, can control significant reduction in conductivity either when the bio-electrode is soaked in water or dried, and is soft and has excellent stretchability and adhesiveness; a bio-electrode including a living body contact layer formed of the bio-electrode composition; and a method for manufacturing the bio-electrode.

Abstract: Presented is an EEG adapter device for eyewear which can be worn invisibly and continuously by the user. The eyewear adapter includes a main body configured in the form of a sleeve so that an intended temple of the eyewear can slidably fit therein, a ring configured to fit over the eyewear's temple and operable by a user to move a first EEG electrode of the eyewear adapter toward or away from the main body to ensure the first EEG electrode is adjustably positioned at FT9/FT10 of the 10-10 system. The eyewear adapter further includes a second EEG electrode and positioned in the vicinity of a bony region behind the user's ears, a third EEG electrode positioned at T9/T10 position of the 10-10 system when in use, and an electronics unit configured to receive and process EEG-related data from the first, the second, and the third EEG electrodes.

Abstract: A myoelectric sensor mounting member includes a mounting portion that is mounted on a measurement site of a living body, and a holding portion that is capable of holding a myoelectric sensor at an optional rotational angle.

Abstract: Systems and methods are disclosed to determine one or more sensing zones on a body surface for electrocardiographic mapping of a region of interest associated with the heart. The sensing zone can be utilized to facilitate acquisition, processing and mapping of electrical activity for the corresponding region of interest. In other examples, an application-specific arrangement of electrodes can also be provided based on the sensing zone that is determined for the region of interest.

Abstract: One aspect of the present invention is an electrode arrangement method for arranging a first-axis positive electrode and a first-axis-negative electrode which is an electrode different from the first-axis positive electrode, wherein the first-axis positive electrode is arranged on a body surface of a wearer, and a first-axis negative electrode is arranged on the body surface of the wearer so that a first observation axis, which is a straight line connecting the first-axis positive electrode and the first-axis negative electrode, passes through a cardiac apex part or a ventricle anterior wall of the wearer.

Abstract: Automatic intraoperative monitoring of new onset conduction disturbances (NOCD) comprising comparison of metric values derived from an ECG signal recording to reference values. An alarm is raised when the comparison result indicates a new onset conduction disorder. Other indications of the comparison may also be presented. Reference values may derive, for example, from a baseline ECG signal recording, and/or from a database of previously observed associations between ECG signals and NOCD. In some embodiments, comparison is also made to threshold values defined by clinical heart block criteria. Baseline and clinical threshold values may define a range used in the comparison. Comparison may combine ranges; for example, using Boolean logic. Comparison and/or alarm triggering is optionally modulated by a database of previously observed associations between non-ECG data and NOCD. Optionally, a user is enabled to select alarm triggering conditions through a user interface.

Abstract: Systems and methods of generating atrial electrical heterogeneity using electrical activity monitored using a plurality of external electrodes are described herein. The atrial electrical heterogeneity may include P-wave electrical heterogeneity. The atrial electrical heterogeneity generated from electrical activity monitored during atrial pacing therapy may be used to evaluate and adjust atrial pacing therapy. The atrial electrical heterogeneity generated from electrical activity monitored during intrinsic activation may be used to evaluate a patient's cardiac condition.

Abstract: A method, apparatus and computer program product, the method comprising obtaining a first electrical signal from a catheter comprising a first electrode distally disposed thereon, when the catheter is inserted into a heart chamber of a heart and the first electrode does not touch a chamber wall; performing statistical analysis of the first electrical signal to obtain a first characteristic of the first electrical signal; obtaining a second electrical signal from the catheter, when a second electrode touches a point on the chamber wall; performing statistical analysis of the second electrical signal to obtain a second characteristic of the second electrical signal; determining a similarity measure between the first characteristic and the second characteristic; and subject to the similarity being below a predetermined threshold, indicating the region as potentially belonging to an arrhythmogenic region of the heart.

Abstract: A medical device is configured to receive sensed cardiac event data including a value of a feature determined from each one of a plurality of cardiac events sensed from a cardiac signal according to a first setting of a sensing control parameter. The medical device is configured to classify each value of the feature of each one of the sensed cardiac events as either a predicted sensed event or a predicted undersensed event according to a second setting of the sensing control parameter that is less sensitive to sensing cardiac events than the first setting. The medical device is configured to determine a predicted sensed event interval between each consecutive pair of the predicted sensed events and predict that an arrhythmia is detected or not detected based on the predicted sensed event intervals.

Abstract: A cardiac diagnostic method includes the following steps: providing an electrocardiogram (ECG) signal; obtaining a body surface potential vector according to the ECG signal; calculating the body surface potential vector and a pre-created mapping tensor to obtain a cardiac potential vector, wherein the mapping tensor is obtained according to a plurality of abnormal positions and a plurality of degree of abnormalities generated by a reference heart; and classifying the abnormal positions and the degree of abnormalities of a detected heart corresponding to the ECG signal according to the cardiac potential vector. In addition, the present disclosure further provides a non-transitory computer-readable medium and system that can operate the above-mentioned cardiac diagnostic method.