Abstract: Instruments, implants, bone plates, systems and methods for correcting bone deformities and fractures in the lower extremity are disclosed. Specifically, targeting instruments, implants, bone plates, systems and methods used for correcting bone deformities and/or fractures in the foot are disclosed.

Abstract: A method of performing a neurovascular procedure includes providing a multi-catheter assembly including an access catheter, a guide catheter, and a procedure catheter, coupling the assembly to a robotic drive system, driving the assembly to achieve supra-aortic access, and driving a subset of the assembly to a neurovascular site. The subset includes the guide catheter and the procedure catheter. The method further includes proximally removing the access catheter and performing a neurovascular procedure using the procedure catheter.

Abstract: A fluid perfusion apparatus includes: a suction conduit for suctioning a fluid from inside a living body; a suction source connected to the suction conduit and configured to suction the fluid at a first flow velocity via the suction conduit; a suction control apparatus connected to the suction conduit and configured to control a flow of the fluid suctioned via the suction conduit; and a control circuit configured to control the suction control apparatus. The control circuit performs control for reversing the flow of the fluid suctioned via inside the suction conduit by the suction control apparatus, to generate a backflow, after controlling suction at the first flow velocity by the suction source for a predetermined period of time and to cause the suction control apparatus to perform re-suction at a second flow velocity greater than the first flow velocity after continuing the backflow for the predetermined period of time.

Abstract: Kidney stone removal system is disclosed having components including a handle mechanism, a nozzle tip, and a guiding device. The handle mechanism employs a trigger that enables control of irrigation and vacuum/suction. Depression of a trigger in the trigger mechanism conveys status of vacuum/suction and irrigation to a user by providing increased resistance at different points of depression. When the trigger is in a home (undepressed) position, irrigation and vacuum/suction are turned off. When the trigger is in a fully depressed position, irrigation and vacuum/suction are turned on. When the trigger is in an intermediate position, irrigation may be turned on, while vacuum/suction remains turned off. The nozzle includes one or more irrigation ports positioned at a distal end of the nozzle and having an irrigation port departure angle of 30 to 60 degrees for directing irrigation fluid forward and laterally from the distal end of the nozzle.

Abstract: A mechanical thrombectomy device including a self-expanding cage structure transitionable from a radially expanded state to a radially partially collapsed state of reduced outer diameter relative to that while in the radially expanded state. The mechanical thrombectomy device also including an internal actuatable collapsing mechanism fixedly attached internally to the self-expanding cage structure; wherein the internal actuatable collapsing mechanism when actuated or deployed imposes a radially inward tension on the self-expanding cage structure transitioning to the radially partially collapsed state compressing the occlusion captured therein.

Abstract: A nested mechanical thrombectomy assembly deliverable as a single assembled unit that includes an outermost mechanical thrombectomy device and at least one inner mechanical thrombectomy device, each mechanical thrombectomy device being actuatable from a radially compressed state to a radially expanded state. While in the radially compressed state, the at least one inner mechanical thrombectomy device is disposed in the inner channel of the outermost mechanical thrombectomy device. Each of the outermost mechanical thrombectomy device and the at least one inner mechanical thrombectomy device is actuatable/deployable independently of one another.

Abstract: Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. The capture system can include a tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening and a capture guide. The capture system can include one or more tensioners coupled to the capture guide. The tubular body has a first configuration in which the first end and the capture guide are expanded while the second end and a majority of the tubular body remains compressed. The tubular body is transformable to a second configuration by application of tension by the tensioners. The catheter can remove a large volume of clot. In some embodiments, the body of the catheter or the funnel tip is expandable. The catheter can include a dilator and a peel-away cover.

Abstract: Disclosed is a clamp that has an actuation portion and an engagement portion coupled with the actuation portion by a coupling portion. The engagement portion includes a first arm having a first engagement element arranged at an end of the first arm, and a second arm having a second engagement element arranged at an end of the second arm. A surgical system is disclosed that includes a clamp with an actuation portion and an engagement portion having a first arm and a second arm. The system includes a cutting guide and a fixation device. A surgical method is disclosed that includes aligning a retention element; releasably coupling a surgical clamp with the retention element; manipulating an actuator; manipulating the surgical clamp; coupling a stabilization wire; reducing an angle between two bones; derotating a bone; inserting a second stabilization wire; making a cut to a bone; and implanting a fusion device.

Abstract: A method is used to manufacture a surgical instrument including a first tube, and a second tube. The first tube extends from a proximal first end portion to a distal first end portion. The second tube extends from a proximal second end portion to a distal second end portion. The second tube is positioned coaxially within the first tube with the distal second end portion positioned adjacent to the distal first end portion. The second tube defines a lumen. The sensor is secured proximal to the distal second end portion of the second tube. A die is engaged against a distal first end portion of the first tube while first tube rotates about its own longitudinal axis; and the die is simultaneously moved relative to the distal first end portion of the first tube along a predetermined path to form a predetermined shape.

Abstract: An end effector is disclosed for use with a surgical robotic manipulator and a cutting accessory. The end effector comprises a nose tube for receiving the cutting accessory and an actuator for driving the cutting accessory. The end effector may also comprise a mounting fixture for coupling the end effector to the surgical robotic manipulator and a handle for gripping by the user. The end effector may also comprise a guard releasably coupled to the cutting accessory for covering a portion of the cutting accessory. A first circuit may be mounted to one of the cutting accessory or the removable guard and a second circuit mounted to the nose tube such that the first circuit and the second circuit configured to communicate with each other when the cutting accessory is coupled to the end effector.

Abstract: A system to treat a patient comprises a user interface that allows a physician to view an image of tissue to be treated in order to develop a treatment plan to resect tissue with a predefined removal profile. The image may comprise a plurality of images, and the planned treatment is shown on the images. The treatment probe may comprise an anchor, and the image shown on the screen may have a reference image marker shown on the screen corresponding to the anchor. The planned tissue removal profile can be displayed and scaled to the image of the target tissue of an organ such as the prostate, and the physician can adjust the treatment profile based on the scaled images to provide a treatment profile in three dimensions. The images shown on the display may comprise segmented images of the patient with treatment plan overlaid on the images.

Abstract: A wire feeding device includes a grip portion that grips and releases the wire and moves in the distal end direction and a proximal end direction; a push spring that biases the grip portion toward the distal end direction; and a slider and a hook that deform the push spring and increase a biasing force. When the deformation of the push spring by the slider and the hook is released, the wire gripped by the grip portion is fed to the distal end direction by the biasing force from the push spring, and the wire feeding device is configured to be operated in (i) a first mode in which the wire is continuously fed in the distal end direction according to a first predetermined operation and (ii) a second mode in which the wire is fed once in the distal end direction according to a second predetermined operation.

Abstract: Devices, methods and systems are described that enable achieving a working diameter that is greater than a resting diameter and to stimulate fluid circulation during high-speed rotation. The drag coefficient of the drive shaft is increased and, in some embodiments, the mass is increased. Among other advantages, the resulting drive shaft with an eccentric element integrated with and/or attached thereto will achieve orbital motion at a rotational speed that is less the rotational speed required to achieve orbital motion without the increased drag coefficient. The concomitant increase in fluid flow and/or fluid stirring at a comparatively lower rotational speed is a further advantage. These characteristics may allow, therefore, a smaller diameter abrasive element to be used which is advantageous in small and/or highly tortuous vessels.

Abstract: Systems and methods for controlling clinical soil are provided. A system includes a device cover formed of a flexible polymer sheet defining an interior volume for a skin grafting device and includes at least a first opening configured to receive a portion of the skin grafting device. The system further includes a cincture having a gasket configured to be affixed to a perimeter of the first opening of the device cover and to secure the device cover about the first opening to the skin grafting device to inhibit fluid ingress into the interior volume of the device cover during a skin grafting process performed using the skin grafting device.

Abstract: Systems and methods for positioning and/or aligning a needle-shaped instrument more easily during an MR image-guided invasive procedure. An insertion apparatus is provided having a pen-shaped main body that has a longitudinal axis. In addition, the insertion apparatus has a guidance facility in or on the main body for guiding the predefined needle-shaped instrument parallel to the longitudinal axis of the main body. In the main body is provided a 3D magnetic field sensor for measuring magnetic field values with respect to three orthogonal spatial directions. A signal interface is used to convey the magnetic field values to an analysis facility external to the insertion apparatus.

Abstract: Subcutaneous implantation tools and methods of implanting a subcutaneous device using the same. The tool may include a tool body having a longitudinally extending recess having a distal opening and having a tunneler at a distal end of the tool body extending from the distal opening of the recess. The tool may include a plunger slidably fitting within at least a portion of the tool body recess. The recess may be configured to receive an implantable device and the tunneler preferably extends distally from the recess at a position laterally displaced from the device when the device is so located in the recess. Movement of the plunger distally within the recess advances the device distally out of the recess and alongside of and exterior to the tunneler.

Abstract: The present disclosure describes delivery cables for delivering a medical device and methods of making and employing the same. In one embodiment, a delivery cable includes a flexible inner core, a proximal outer coil, and a distal outer coil. The proximal outer coil has a first rigidity. The distal outer coil surrounds at least a portion of a distal section of the flexible inner core and has a second rigidity less than the first rigidity thereby, thereby reducing bias placed on the medical device by the delivery cable during deployment of the medical device. Relative dimensions of an outer diameter of the distal outer coil and an inner diameter of a delivery sheath for deploying the delivery cable reduce snaking of the delivery cable within the delivery sheath.

Abstract: Disclosed herein are methods and systems for treating an intervertebral disc in a subject in need thereof. In some embodiments, the subject's intervertebral disc has a reduced disc height due to degeneration, damage, and/or disease. In other embodiments, the subject is at risk of losing height in at least one intervertebral disc. In most embodiments, the disclosed methods comprise inserting a needle into the treated disc a first time and a second time. In many embodiments the first and second time may be separated by a period of days or weeks.

Abstract: A uterine manipulator can include a shaft including a first end, a second end, and a channel along an axis of the shaft, a handle coupled to the first end of the shaft, and a triangular balloon coupled to the second end of the shaft. The triangular balloon can be configured to inflate upon insertion into a vagina via a fluid injected into the channel of the shaft.

Abstract: A uterine manipulator includes a housing configured to be coupled to an instrument drive unit of a robotic system, a shaft extending distally from the housing, a tip hub pivotably coupled to a distal end portion of the shaft, an articulation disposed within the housing, and a handle operably coupled to either the housing or the shaft. The articulation assembly is configured to pivot the tip hub relative to the shaft and includes a drive cable operably coupled to the tip hub. The articulation assembly is actuatable manually by a user and robotically by the robotic system to pivot the tip hub relative to the shaft.

Abstract: A surgical instrument includes a driver shaft couplable to a cannulated pedicle screw. The driver shaft having a through bore for conveying a surgical guide wire through the cannulated pedicle screw. The surgical instrument also includes a wire positioning assembly having a positional adjustment mechanism for adjusting an axial position of the surgical guide wire with respect to the cannulated pedicle screw and a locking mechanism for locking the axial position of the surgical guide wire. Additionally, the surgical instrument includes a driver actuator coupled to the driver shaft. The driver actuator is operable to rotate the driver shaft to drive rotation of the cannulated pedicle screw.

Abstract: Bone anchor assemblies are disclosed herein that can provide for improved fixation as compared with traditional bone anchor assemblies. An exemplary assembly can include a bracket or wing that extends down from the receiver member and accommodates one or more auxiliary bone anchors that augment the fixation of the assembly's primary bone anchor. Another exemplary assembly can include a plate that is seated between the receiver member and the rod and accommodates one or more auxiliary bone anchors that augment the fixation of the assembly's primary bone anchor. Another exemplary assembly can include a hook that extends out from the receiver member to hook onto an anatomical structure or another implant to augment the fixation of the assembly's primary bone anchor. Surgical methods using the bone anchor assemblies described herein are also disclosed.

Abstract: The present invention is directed an anchor assembly for use in spinal fixation to interconnect a longitudinal spinal rod with a patient's vertebra. The anchor assembly preferably includes a bone anchor, a body with a rod-receiving channel, an insert member (preferably a bushing), and a locking cap with a saddle. The anchor assembly preferably enables in-situ assembly where the bone anchor may be secured to the patient's vertebra prior to being received within the body of the bone anchor assembly. Accordingly, the anchor assembly enables a surgeon to implant the bone anchor without the body to maximize visibility and access around the anchoring site. Once the bone anchor has been secured to the patient's vertebra, the body may be snapped onto the bone anchor and a spinal rod may be inserted into the rod-receiving channel.

Abstract: A receiving part for receiving a rod for coupling the rod to a bone anchoring element, the receiving part including: a receiving part body having a channel for receiving a rod and defining an accommodation space for accommodating a head of a bone anchoring element, the accommodation space having an opening for inserting the head; and a pressure element at least partially in the accommodation space, the pressure element including a first portion having a recess to receive the rod, and a second portion having a flexible portion to clamp the head, wherein the pressure element is moveable along a longitudinal axis of the receiving part body from an inserting position to insert the head, to a pre-locking position to clamp the head in the receiving part by a pre-stress exerted by the pressure element, to a locking position to lock the head in the receiving part.

Abstract: A receiver assembly includes a receiver with a base defining a central bore for receiving the head of a bone anchor and upright arms defining a channel for receiving a rod, with the central bore having through apertures extending outwardly to outer side surfaces of the receiver and the upright arms having top surfaces, opposite front and back surfaces, vertical tool-engaging slots extending downward from the top surfaces to the through apertures for slidably receiving an insert compression tool, and horizontal tool-engaging grooves on either side of the vertical slots that extend laterally to a front or back surface of the upright arm. The assembly also includes an insert positionable within the central bore with an upward-facing outer engagement surface located within a through aperture and aligned with a vertical tool-engaging slot, and which is configured for compressive engagement by the insert compressing tool to independently lock a position of the receiver with respect to the bone anchor.

Abstract: A coupling device for use with a bone anchoring element includes a receiving part having first and second ends, a longitudinal axis, and a coaxial passage, and a pressure member having a first portion and an expandable portion connected axially to the first portion forming a seat for the head. The pressure member is movable to a position where the receiving part acts on the expandable portion to clamp the head in the seat. The seat can be asymmetric relative to the longitudinal axis while a central axis of the first portion is coaxial with the longitudinal axis, such that the seat facilitates pivoting of the bone anchoring element in a first direction to a first maximum angle and in an opposite direction to a second maximum angle smaller than the first maximum angle.

Abstract: A spinal fixation access and delivery system is disclosed. In some aspects, the system is used to access the cervical facet joint via a posterior access approach. The system may include an access device including a body having a proximal portion and a distal portion and a chamfered or beveled end feature positioned at the distal portion of the body and configured for insertion at the cervical facet joint. The system may further include a guide device having access device engagement features and a spinal fixation member. The access device includes at least one guide device receiving feature complementary to or keyed to the engagement feature of the guide device.

Abstract: A method for treatment of a sacral insufficiency fracture comprises a plurality of steps. A step is performed for placing an access device within a patient. Such placing of the access device includes causing a distal end portion of the access device to traverse through a sacroiliac joint of the patient and to traverse into the patient's sacrum until the distal end portion of the access device is within a region of the sacrum where a sacral insufficiency fracture is located. Thereafter, a step is performed for delivering bonding material though a portion of the access device into the sacrum at the region thereof where the sacral insufficiency fracture is located.

Abstract: Catheter system, devices and methods for diagnosing and treating lateral stenosis causing back pain and or leg pain. The devices comprise a tubular part for insertion into a working cannula to self-position itself safely within the foramen, and minimize the risk of displacement medially or laterally, to prevent nerve or dura injury. An expandable membrane is configured to maintain the catheter device within the foramen. Expansion of this membrane would decompress the nerve within the foramen by opening the foraminal canal as the membrane expands.

Abstract: Implants, guides, devices, instruments, systems and methods for fixing a joint using bone plates are disclosed. The bone fixation system includes an alignment guide with a first end and a second end, an alignment wire rotatably coupled to the first end of the alignment guide, and a coupling member slidingly engaging a first portion of the alignment guide near the first end. The plate includes a body including a first end and a second end, a plurality of lobes extending from the body, a plurality of screw holes extending through the body and each screw hole of the plurality of screw holes positioned in a lobe of the plurality of lobes, and an alignment hole positioned along a longitudinal axis of the body. A method of using a bone fixation system for fixation of at least two bones is also disclosed.

Abstract: A medical impact instrument, in particular in the form of an impact hammer, includes a shaft defining a shaft longitudinal direction, a proximal end and a distal end. An impact body is arranged on the shaft and defines a longitudinal axis. The impact body is movable in an impact position on the shaft between a distal stop defining a distal stop position of the impact body and a proximal stop defining a proximal stop position of the impact body for transmitting an impact pulse to the distal end of the shaft in the distal or proximal direction. The impact instrument includes a fixing device for temporarily fixing the impact body to the shaft in at least one, in particular arbitrary, fixing position between the distal stop position and the proximal stop position.

Abstract: A cryoablation catheter assembly is described. The assembly comprises (a) an inlet for receiving an input flow of refrigerant fluid, (b) a cryo-applicator, (c) a flow splitter configured to split the input flow into a therapeutic flow portion and a precooling flow portion, and (d) a precooling arrangement configured to precool the therapeutic flow portion and guide the precooled therapeutic flow portion towards the cryo-applicator, wherein the precooling arrangement comprises a heat exchanger configured to apply an adjustable precooling power from the precooling flow portion to the therapeutic flow portion. Furthermore, a cryoablation system and a method are described.

Abstract: A cryosurgical system includes a probe system including a cryosurgical probe and a temperature probe; an imaging system; and a computer system operatively connected to the probe system and the imaging system and programmed with a graphical depth guide application that provides a graphical overlay on an image from the imaging system that includes a first scale of first spaced markers representing temperature of the temperature probe and a second scale of second spaced markers representing a distance from the cryosurgical probe to an imaging probe of the imaging system that provide a visual guide for locating the cryosurgical probe during surgery.

Abstract: A fluid drug delivery system that includes an actuator connected to a valve for releasing a pressurized treatment fluid. A fluid chamber can be included that is configured to include the pressurized treatment fluid and include a volume that changes in response to the release of the pressurized treatment fluid. An external pressure interface can be in fluid communication with the fluid chamber. A pressure sensor-display dial can be included operatively connected to the fluid chamber and the external pressure interface to monitor fluid pressure of the fluid chamber and direct the operator to the correct pressure application.

Abstract: A method for performing a therapeutic procedure includes applying therapy to target tissue, measuring a property of the target tissue at a plurality of spaced apart locations along the length of the target tissue, identifying changes in the measured property of the target tissue at each of the plurality of spaced apart locations, identifying a point in time at which the identified change in the measured property occurs at each of the plurality of spaced apart locations, and calculating a pulse wave velocity within the target tissue by comparing a difference between the identified points in time at which the identified change in the measured property occurs at at least two of the plurality of spaced apart locations, wherein the calculated pulse wave velocity is predictive of a response to therapy.

Abstract: Electronic apparatus (100) for delivering Coherent Sine Burst Irreversible Electroporation energy to a biological tissue (1) comprises at least one electrode (3) positionable on or near the biological tissue (1), a power generator (2) for supplying electric energy to the electrode (3), and to generate a respective electric signal (S) to energize the electrode (3). The electric signal (S) is formed by alternating over time a first electric signal (S1) with a second electric signal (S2), with each first electric signal (S1) being the same. The first electric signal (S1) is supplied to electrode (3) during a first time interval (T1) and the second electric signal (S2) is supplied to electrode (3) during a second time interval (T2), subsequent to the first time interval (T1). The first electric signal (S1) is a continuous bipolar signal which comprises two or more basic sine waves (SB) in the first time interval (T1).

Abstract: Described herein are monopolar treatment delivery systems, and methods for use therewith. Such a system can include an energy delivery electrode, a dispersive electrode, a reference electrode, and a generator in electrical communication with the energy delivery electrode, the dispersive electrode, and the reference electrode. The generator is configured to deliver an impedance measurement signal to target tissue using the energy delivery electrode and the dispersive electrode, while the energy delivery electrode is proximate to the target tissue and the dispersive electrode is remote from the target tissue. The generator is also configured to measure a voltage between the energy delivery electrode and the reference electrode, and to monitor impedance of the target tissue based on a current of the impedance measurement signal and the voltage between the energy delivery electrode and the reference electrode. The monitored impedance can be used, e.g., to deduce a treatment effect outcome.

Abstract: A method and apparatus are disclosed for puncturing and using the puncturing device to evaluate and identify the anatomical space that the puncturing device has entered. The physician can then determine if the puncturing device has entered the desired anatomical space or an unintended anatomical space.

Abstract: A cautery pen tip accessory cover comprises a cylindrical member that can receive a cautery pen in a first end and the tip of the cautery pen can extend from a second opposite end when the cover is in a retracted configuration. The cylindrical member has an opened lateral exposure that allows the feel of the cautery pen therethrough. A cover exposure opening in the cylindrical member to provide access to a trigger of the cautery pen when the cautery pen tip cover is in the retracted configuration. The cylindrical member is easily retracted, allowing easy retraction of the cover by the operator squeezing the cover to a resistance bar stabilization system accessory configured over the cautery pen. The cover can include a suction device that removes blood and debris as well as the smoke plume to exist in a single instrument.

Abstract: A method of treating tissue includes clamping tissue between an ultrasonic blade and a jaw member and simultaneously: transmitting ultrasonic energy to the ultrasonic blade to vibrate the ultrasonic blade at a first blade velocity thereby heating the clamped tissue; and supplying electrosurgical energy, at a constant voltage, to the jaw member and the ultrasonic blade at different potentials such that the electrosurgical energy is conducted therebetween and through the clamped tissue to heat the clamped tissue. An impedance of the clamped tissue is monitored and the simultaneous transmission of ultrasonic energy and supply of electrosurgical energy is terminated and/or a notification is output once the clamped tissue is sealed, as indicated by the impedance of the clamped tissue being equal to or greater than a threshold impedance. Surgical instruments and end effectors thereof for treating tissue in this manner are also provided.

Abstract: A surgical instrument for electrosurgery having a first forceps arm, a first forceps jaw of the first forceps arm, a first conductor tip of the first forceps arm, a second forceps arm disposed opposite the first forceps arm, a second forceps jaw of the second forceps arm, the second forceps jaw disposed opposite the first forceps jaw, a second conductor tip of the second forceps arm, and the second conductor tip disposed opposite the first conductor tip. The first forceps arm and the second forceps arm are configured to transfer thermal energy away from the first conductor tip and second conductor tip at a rate sufficient to maintain the thermal energy of the first conductor tip and second conductor tip below a designated thermal threshold. The first and second forceps arms being composed of a zirconium copper alloy.

Abstract: An ablation device, the device comprising: a sheath; a plurality of needle electrodes that are each extendible from a distal end of the sheath; and a controller that is configured to selectively apply a power signal between specified pairs of needle electrodes of the plurality of needle electrodes, when the plurality of needle electrodes are in contact with a tissue, so as to ablate a desired region of said tissue.

Abstract: Methods and systems for spinal radio frequency neurotomy. Systems include needles capable of applying RF energy to target volumes within a patient. Such target volumes may contain target medial branch nerves along vertebrae or rami proximate the sacrum. Such procedures may be used to ablate or cauterize a portion of the targeted nerve, thus blocking the ability of the nerve to transmit signals to the central nervous system. Disclosed needles may be operable to asymmetrically, relative to a central longitudinal axis of the needle, apply RF energy. Such asymmetry facilitates procedures where a tip of the needle is placed proximate to anatomical structures for location verification. Then RF energy may be applied in a selectable direction relative to the needle tip to ablate volumes that include the targeted medial branch nerves or rami, thus denervating facet joints or the sacroiliac joint, respectively, to relieve pain in a patient.

Abstract: An elongated medical sheath is configured to be movable and positionable proximate to a biological feature of a patient. An expandable-and-collapsible support structure is configured to be selectively movable, at least in part, between an interior of the elongated medical sheath and an exterior of the elongated medical sheath. An energy-emitting assembly is supported by the expandable-and-collapsible support structure.

Abstract: The tissue cutting device comprises an elongated assembly including both an outer sleeve and an inner sleeve. The outer sleeve has a tissue-receiving window, and the inner sleeve has a distal end which cuts tissue as the inner sleeve is advanced past the window. The tissue is received into a lumen of the inner sleeve, and the inner sleeve lumen is typically enlarged in a proximal direction to reduce the tendency of resected tissue to lodge therein. The tissue displacement member is optionally provided at a distal end of the outer sleeve to further aid in dislodging tissue which becomes captured in a distal end of the inner sleeve of the lumen.

Abstract: An electric wire connection structure is provided with a plurality of insulated electric wires with each core wire being covered with an insulation coating. The core wires are connected to pads provided on a substrate. The plurality of insulated electric wires are arranged parallel to each other on the substrate along a predetermined alignment direction. The insulation coatings are removed in part in respective longitudinal directions to expose the core wires, and exposed portions of the core wires are connected to the pads, respectively. The exposed portions of the core wires are arranged along an inclined direction inclined with respect to a longitudinal direction of the plurality of insulated electric wires and the alignment direction.

Abstract: An electric wire connection structure is provided with a plurality of insulated electric wires. Each insulated electric wire includes a core and an outer periphery of a core wire is covered by an insulation coating. The core wire is connected by an electrically conductive bonding material to each of a plurality of pads provided on a substrate at a tip in a longitudinal direction of each of the plurality of insulated electric wires. For each of the plurality of insulated electric wires, an end surface of the core wire and an end surface of the insulation coating are at the same position at the tip in the longitudinal direction, and the electrically conductive bonding material adheres to the end surface of the core wire and the pads.

Abstract: A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108A) of a blood vessel (108) within a body (107) of a patient (109) includes a first energy guide (222A), a second energy guide (222A), and a routing assembly (280). The routing assembly (280) defines a routing space (282) that retains a routing length (222L) of each of the energy guides (222A), the routing assembly (280) including an inner routing guide (287) that is positioned within the routing space (282), the routing length (222L) of each of the energy guides (222A) each being positioned at least partially about the inner routing guide (287), the routing space (282) being configured so that the routing length (222L) of at least one of the energy guides (222A) is adjustable.

Abstract: An example receptacle connector for a catheter for performing pulsed field ablation (PFA). The receptacle connector includes a first side to receive electrical signals; a second side, opposite to the first side, to transfer the electrical signals to a plurality of electrodes; a surface on the first side; and a plurality of groups of pins extending from the surface. Each of the groups of pins includes at least one pin to electrically connect to a power source to receive the electrical signals, and an interlocking wall surrounding the at least one pin.

Abstract: Devices, systems, and methods of the present disclosure can overcome physical constraints associated with catheter introduction to facilitate the use of a catheter with a large distal portion as part of a medical procedure benefitting from such a large distal portion, such as, for example, cardiac ablation. More specifically, devices, systems, and methods of the present disclosure can compress an expandable tip of a catheter from an expanded state to a compressed state along a tapered surface of an insertion sleeve for advancement of the expandable tip into vasculature of a patient. The tapered surface of the insertion sleeve can, for example, apply compressive forces at an angle against the advancing expandable tip. As compared to other approaches to the application of compressive force to an expandable tip, compressing the expandable tip using an angled force can reduce the likelihood of unintended deformation of the expandable tip.