Abstract: A method of generating a computer-based observable model of an implantable repair material secured to a patient is provided. The method includes processing data corresponding to a patient using a computing device including a processor and a memory storing a software application executable by the processor. The method also includes indicating an implantable repair material and a fixation for securing the implantable repair material to the patient and indicating a distribution of the fixation about the implantable repair material. The method also includes generating an observable model of the implantable repair material secured to the patient on a display operably associated with the computing device. The observable model depicts the indicated distribution of the fixation about the implantable repair material.

Abstract: Systems and methods may use an augmented reality device during a surgical procedure. The systems and methods may use an augmented reality display of an augmented reality device to present or project a virtual feature during a surgical procedure while permitting physical aspects of a surgical field to be viewed through the augmented reality display. The virtual feature may include aspects of a preoperative plan, a surgical device, an anatomical aspect of a patient, etc.

Abstract: A system for surgical planning and assessment of spinal deformity correction is provided that has a spinal imaging system and a control unit. The spinal imaging system is configured to collect at least one digitized position of one or more vertebral bodies of a subject. The control unit is configured to receive the at least one digitized position, and calculate, based on the at least one digitized position, an optimized posture for the subject. The control unit is configured to receive one or more simulated spinal correction inputs, and based on the inputs and optimized posture, predict an optimal simulated postoperative surgical correction.

Abstract: A method includes emitting an ultrasound beam, having a predefined field of view (FOV), from an array of ultrasound transducers in a catheter in an organ of a patient. Echo signals are received in the array, in response to the ultrasound beam. A position of a target object is estimated within the FOV. When the estimated position of the target object violates a centering condition, the FOV of the ultrasound beam is automatically modified to re-meet the centering condition.

Abstract: This document describes devices used during surgical procedures for the treatment of heart conditions. For example, this document describes technology to monitor the operations of a heart-lung machine and then shows associated read outs on a head-worn display in order to provide an augmented-reality presentation. For example, various sensors on and around a heart-lung machine, patient, and/or extracorporeal circuit can monitor the operations of the procedure using the heart-lung machine.

Abstract: Disclosed herein are various robotic surgical systems having various robotic devices. Further, disclosed herein are removable coupleable connection ports, each of which can be coupled to a robotic device and a camera assembly that is disposed into and through the robotic device. Also disclosed herein are removable connection ports having at least one of a elongate device body coupling mechanism, a camera assembly coupling mechanism, and/or a presence detection mechanism. Further discussed herein is a camera assembly with at least one actuation mechanism for actuating movement of the steerable distal tip thereof.

Abstract: A robotic device for a minimally invasive medical intervention on soft tissues is provided. The robotic device uses a medical instrument having a robot arm having several degrees of freedom and having an end suitable for receiving the medical instrument, an image capture system suitable for capturing position information concerning the anatomy of the patient, a storage medium having a biomechanical model of the human body, a processing circuit configured to determine a position setpoint and an orientation setpoint for said medical instrument on the basis of the biomechanical model, on the basis of the position information and on the basis of a trajectory to be followed by the medical instrument in order to perform the medical intervention, and a control circuit configured to control the robot arm in order to place the medical instrument in the position setpoint and the orientation setpoint.

Abstract: Some embodiments are directed to a surgical robotic system for use in a surgical procedure, including a surgical arm having a movable arm part for mounting of a surgical instrument having at least one degree-of-freedom to enable longitudinal movement of the surgical instrument towards a surgical target. Some other embodiments are directed to a human machine interface for receiving positioning commands from a human operator for controlling the longitudinal movement of the surgical instrument, and an actuator configured for actuating the movable arm part to effect the longitudinal movement of the surgical instrument, and controlled by a processor in accordance with the positioning commands and a virtual bound. The virtual bound establishes a transition in the control of the longitudinal movement of the surgical instrument in a direction towards the surgical target. The virtual bound is determined, during use of the surgical robotic system, based on the positioning commands.

Abstract: Systems and methods for performing concomitant medical procedures are disclosed. In one aspect, the method involves controlling a first robotic arm to insert a first medical instrument through a first opening of a patient and controlling a second robotic arm to insert a second medical instrument through a second opening of the patient. The first robotic arm and the second robotic arm are part of a first platform and the first opening and the second opening are positioned at two different anatomical regions of the patient.

Abstract: Surgical systems, methods and surgical planning programs to facilitate preparation of an anatomical cavity to receive a cup implant. The system includes a control system, a localizer and a robotic manipulator configured to move an energy applicator that is adapted to remove tissue. The control system obtains or generates a surgical plan that defines characteristics of cement holes to be formed within a wall of the anatomical cavity for receiving bone cement. The control system registers the surgical plan to the anatomical cavity with the localizer and controls the robotic manipulator to utilize the energy applicator to form the cement holes within the wall of the anatomical cavity according to the surgical plan.

Abstract: An apparatus includes a cart having a vertical adjustment element configured to adjust a distance between the platform and a ground supporting the cart, the cart defining a surface for supporting an arm of the patient. The apparatus includes a manipulation device including a plurality of motors each configured to operably couple to a different one of a needle, a catheter, and a guidewire to selectively advance one or more of the needle, the catheter, and the guidewire, and a robotic arm having a first end mounted to the cart and a second end coupled to the manipulation device, the robotic arm having a plurality of segments joined together via a plurality of joints such that the robotic arm can be moved to position the needle, the catheter, and the guidewire for insertion into a target vessel in the arm.

Abstract: A computer-assisted medical system includes a manipulator arm and an instrument holder physically coupled to the manipulator arm. The instrument holder is configured to releasably couple to an instrument. The instrument holder includes an adjustable assembly and a cannula clamp physically coupled to the adjustable assembly. A physical adjustment of the adjustable assembly moves the cannula clamp relative to the manipulator arm. The cannula clamp is configured to releasably couple to a cannula configured to receive the instrument.

Abstract: A medical imaging system comprises a teleoperational assembly which includes a medical instrument including an instrument tip and an imaging instrument including an imaging instrument tip. The medical imaging system also comprises a processing unit including one or more processors. The processing unit may be configured to determine an instrument tip position for the instrument tip, determine an instrument tip position error relative to the imaging instrument, and determine at least one instrument tip bounding volume based on the determined instrument tip position, the determined instrument tip position error, and a ratio between an error radius of the instrument tip position error and a size of a display screen.

Abstract: A medical device for retrieval of kidney stone fragments from a urinary tract is provided. The medical device has a plurality of magnets arranged within a flexible sheath forming a flexible wire. The magnets are magnetically attached end-to-end and arranged with their magnetic polarities alternating in direction. The magnetization direction of each of the magnets is orthogonal to the length axis of the flexible wire. A removable inner stylet is situated within the flexible sheath allowing for modifiable flexibility of the wire. The medical device is dimensioned to be introduced into the urinary tract and standard endoscopic devices. The medical device is further dimensioned to allow for the wire with magnetically attached stone fragments to be retrieved from the urinary tract. The magnetic field along the length axis is sufficient to attract to the surface of the flexible wire superparamagnetic nanoparticles which have bound themselves to kidney stone fragments.

Abstract: A method for engaging and disengaging a surgical instrument of a surgical robotic system including receiving a sequence of user inputs from one or more user interface devices of the surgical robotic system; determining, by one or more processors communicatively coupled to the user interface devices and the surgical instrument, whether the sequence of user inputs indicates an intentional engagement or disengagement of a teleoperation mode in which the surgical instrument is controlled by user inputs received from the user interface devices; in response to determining of engagement, transition the surgical robotic system into the teleoperation mode; and in response to determining of disengagement, transition the surgical robotic system out of the teleoperation mode such that the user interface devices are prevented from controlling the surgical instrument.

Abstract: A surgical robotic component comprising an articulated terminal portion, the terminal portion comprising: a distal segment having an attachment connected thereto, an intermediate segment, and a basal segment whereby the terminal portion is attached to the remainder of the surgical robotic component. The terminal portion further comprises a first articulation between the distal segment and the intermediate segment, the first articulation permitting relative rotation of the distal segment and the intermediate segment about a first axis, and a second articulation between the intermediate segment and the basal segment, the second articulation permitting relative rotation of the intermediate segment and the basal segment about a second axis.

Abstract: A sterile barrier for a robotic drive comprises a first drive module configured to move moving along a longitudinal axis of a drive body. The sterile barrier comprises a first resilient member having a first free edge proximate the longitudinal axis. The first free edge adjacent the first drive module is resiliently biased away from and returned to the longitudinal axis as the first drive module moves along the longitudinal axis.

Abstract: Devices and methods for the treatment of heart conditions, and other medical purposes, include cardiac pacing systems. For example, this document describes temporary transvenous endocardial pacemaker systems and devices for deploying such systems without the need for conventional imaging procedures.

Abstract: A frequency modulated continuous wave radar system includes at least one identity tag, respectively disposed next to at least one test subject; and a frequency modulated continuous wave radar identity recognition device, including an identity recognition control module, for controlling a test identity tag of the at least one identity tag to be turned on to generate a specific tag reflection signal corresponding to an identity frequency in response to a chirp signal; and a frequency modulated continuous wave radar, for transmitting the chirp signal and receiving at least one reflection signal of the at least one test subject and the specific tag reflection signal in response to the chirp signal, to calculate and determine that the specific tag reflection signal and a specific reflection signal of the at least one reflection signal are corresponding to an adjacent position information. The specific reflection signal is corresponding to test subject information.

Abstract: Interstitial brachytherapy is a cancer treatment in which radioactive material is placed directly in the target tissue of the affected site using an afterloader. The accuracy of this placement is monitored in real time using a urinary catheter that locates the radioactive material according to the radiation levels measured by sensors in the walls of the urinary catheter. A scintillator that is embedded in the walls of the urinary catheter produces light when irradiated by the radioactive material. This light is proportional to the level of radiation at each location. The light produced by each scintillator is carried through optical fibers and then converted to an electrical signal that is proportional to the light and the radiation level at each location. The radioactive material is located according to the plurality of electrical signals. This location can be used as quality control feedback to the afterloader.

Abstract: Embodiments of the present disclosure are directed to optical instruments and methods with a head mounted camera on a subject to provide a compact and lightweight solution to imaging specimen from the brain of a subject thereby providing closer proximity imaging with minimal or negligible effect to the subject's ability to physically move and rotate freely. The head mounted camera includes a light source for illuminating light through a beamsplitter to an image lens implant, which has been surgically inserted in the brain of the subject. The head mounted camera also includes an image sensor for imaging the top surface of the imaging lens implant and for capturing and transmitting images of neurons from deep inside the brain of the subject to the image sensor.

Abstract: A wearable article includes: an annular casing that surrounds a space into which a body of a user is to be inserted; a light-emitting element that is provided in the casing, the light-emitting element emitting light towards the space; an imaging element that is provided in the casing, the imaging element capturing and obtaining an image of the space when the light-emitting element emits light; and an authentication circuit that authenticates the user based on a vein pattern obtained in advance and the image.

Abstract: In certain embodiments, the invention relates to systems and methods for in vivo tomographic imaging of fluorescent probes and/or bioluminescent reporters, wherein a fluorescent probe and a bioluminescent reporter are spatially co-localized (e.g., located at distances equivalent to or smaller than the scattering mean free path of light) in a diffusive medium (e.g., biological tissue). Measurements obtained from bioluminescent and fluorescent modalities are combined per methods described herein.

Abstract: An illustrative optical measurement system includes a light source configured to emit light directed at a target, an array of photodetectors configured to detect photons of the light after the light is scattered by the target, and a processing unit. The processing unit is configured to measure a noise level of a photodetector included in the array of photodetectors and determine that the noise level meets a predetermined threshold. The processing unit is further configured to prevent, based on the determining that the noise level meets the predetermined threshold, an output of the photodetector from being used in generating a histogram based on a temporal distribution of photons detected by the array of photodetectors.

Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.

Abstract: The present invention relates to a three-dimensional oral scanner. In particular, the present invention comprises: a case which can be drawn in and out of an oral cavity and has an opening formed in a manner such that the shape of the inside of the oral cavity (hereinafter, abbreviated as “image”) is introduced to the inside in the form of light through one end thereof; a pair of lenses disposed inside the case and spaced apart from each other in the width direction of the case so as to pass light incident from one end of the case in different paths; a pair of imaging boards having an imaging sensor for imaging the respective lights transmitted through the pair of lenses and disposed in close contact with a widthwise side wall and the other widthwise side wall of the case; and a pair of light path changing units arranged to change the respective paths of the lights transmitted through the pair of lenses toward the imaging board.

Abstract: A robotic system includes retrieval of a priori stimulus based on an input that indicates a current health state and a target health state of a user. A set of test stimuli specific for the user is determined and a stimulus device is controlled to provide the set of test stimuli to the user. A first set of responses within the body of the user and a second set of responses discernible on the body of the user are determined, and a set of stimulus parameters for the stimulus device is calibrated based on the combination of the first set of responses, the second set of responses, the current health state, the target health state, and a trained AI-based system. A new stimulus is applied to a portion of the body of the user that shifts a condition of the user from the current health state towards the target health state.

Abstract: Embodiments disclosed herein involve a wearable-based system that can help determine in a privacy-preserving manner whether a user is healthy (and thus poses low risk of contagiousness), and use determinations of this nature to grant passage through a doorway. In one embodiment, a wearable device takes measurements of a user comprising a photoplethysmogram signal (PPG signal) and a temperature measurement. A computer calculates a health score based on a difference between baseline measurements of the user, measured one or more days earlier, and more current measurements of the user. Additionally, the computer calculates an extent of similarity between characteristics of the PPG signal in the current measurements and characteristics of the PPG signal in the baseline measurements. The computer authorizes the user's passage through the doorway responsive to the health score reaching a first threshold and the extent of the similarity reaching a second threshold.

Abstract: Described herein are systems, devices, and methods for cardiac monitoring. In particular, the systems, devices, and methods described herein may be used to conveniently sense the presence of an intermittent arrhythmia in an individual. The systems, devices, and methods described herein may be further configured to sense an electrocardiogram.

Abstract: A method and system for continually monitoring oxygenation levels in real-time in compartments of an animal limb, such as in a human leg or a human thigh or a forearm, can be used to assist in the diagnosis of a compartment syndrome. The method and system can include one or more near infrared compartment sensors in which each sensor can be provided with a compartment alignment mechanism and a central scan depth marker so that each sensor may be precisely positioned over a compartment of a living organism. The method and system may comprise hardware or software (or both) may adjust one or more algorithms based on whether tissue being monitored was traumatized or is healthy. The method and system can also monitor the relationship between blood pressure and oxygenation levels and activate alarms based on predetermined conditions relating to the oxygenation levels or blood pressure or both.

Abstract: Certain aspects of the present disclosure provide methods, apparatus, and computer-readable media for determining hemodynamic stability in a subject. In one example method, an optical signal is transmitted via at least one optical fiber in a set of one or more optical fibers partially disposed in a heart of the subject, wherein the at least one optical fiber in the set is configured to bend with the mechanical movement of the heart. A reflected portion of the optical signal is received via the at least one optical fiber, wherein changes in at least one parameter of the received reflected portion of the optical signal are indicative of the mechanical movement of the heart. A hemodynamic stability of the heart is determined based on the received reflected portion. Hemodynamic stability of the subject may further be determined based on thermal, ultrasound, and/or impedance signals measured in or near the heart.

Abstract: A blood pressure measuring apparatus includes a pressure control unit that controls an applied pressure applied to a region of a living body in which a vein and artery exist by a cuff mountable to the region, a detection unit that detects pressure waveforms in which pulse wave components from the region overlap with the applied pressure, and an analysis unit that obtains a respiratory variation on the waveform of artery and a venous pressure based on the pressure waveforms detected by the detection unit through one-time blood pressure measurement. The analysis unit obtains the respiratory variation on the waveform of artery based on data of a first pressure waveform in a first process, and the venous pressure based on data of a second pressure waveform in a second process and the data of the first pressure waveform.

Abstract: An apparatus for estimating bio-information includes a sensor part configured to measure a pulse wave signal and a contact force of an object, while the object is in contact with the sensor part. The apparatus further includes a processor configured to extract a first feature from the measured pulse wave signal and the measured contact force, select one estimation model from a plurality of estimation models, based on a second feature of a user corresponding to the object, and estimate the bio-information, by inputting the extracted first features in the selected estimation model.

Abstract: Systems, devices, and methods for optimizing a physiological measurement are described herein. A system may include a wearable band that is wearable by a subject, a user device attached to the wearable band, and a measurement device configured to the physiological measurement. The user device may include a first communication device and a user interface. The measurement device may include a hollow housing, a processing device disposed within the housing, an elastic coupling member disposed within the housing, a physiological sensor coupled to the housing by the elastic coupling member, and a second communication device. The physiological sensor may take the physiological measurement and communicate the physiological measurement to the user device. The user interface may display the physiological measurement to the subject. The physiological measurement device and the user device may be attached to the same wearable band that is worn by the subject.

Abstract: A triboelectric wearable device (100) and a method for physiological monitoring, comprising: a support element (101); a first element (102) consisting of a first metallic contact (102a) and a second metallic contact (102b) between which is placed a dielectric layer, said first element (102) being able to be placed in contact with a wrist (50) of a user and bonded to the support element (101); a second element (103) overlapped and bonded to the first element (102) and to the support element (101). The triboelectric wearable device (100) further comprises an electronic interface (104) for acquiring and processing the signal generated by means of the triboelectric effect in the blood vessels of the user near the wrist (50), said electronic interface (104) being housed into the support element (101) and connected to the first metallic contact (102a) and to the second metallic contact (102b) of the first element (102).

Abstract: A diagnostic system includes one or more blood flow sensors adapted to contact but not penetrate the skin of the pedal arch and aligned with blood vessels of the pedal arch. Readings from the blood flow sensors are transformed into blood flow acceleration times, and the blood flow acceleration times are used to identify a blood flow pathology.

Abstract: A non-invasive analyte sensor device that includes a sensor housing, and a decoupled antenna/detector array having at least one transmit antenna/element and at least one receive antenna/element. The sensor housing has a maximum length dimension no greater than 50 mm, a maximum width dimension no greater than 50 mm, a maximum thickness dimension no greater than 25 mm, and a total interior volume of no greater than about 62.5 cm3. In addition, the at least one transmit antenna/element and the at least one receive antenna/element have a maximum spacing therebetween that does not exceed 50 mm and a minimum spacing therebetween that is at least 1.0 mm, and the at least one transmit antenna/element and the at least one receive antenna/element are less than 95% coupled to one another, or less than 90% coupled to one another, or less than 85% coupled to one another, or less than 75% coupled to one another.

Abstract: Provided herein are devices, systems, and methods for monitoring lesion or treated area in a tissue during focal ablation or cell membrane disruption therapy.

Abstract: A method to automatically align magnetic resonance (MR) scans for diagnostic scan planning includes acquiring a three-dimensional (3D) localizer image of an anatomical object. One or more initial landmarks are identified in the 3D localizer image using a landmarking engine. One or more main axes associated with the anatomical object are identified based on the one or more initial landmarks. The 3D localizer image is registered to a canonical space based on the main axes associated to yield a registered 3D localizer image. The landmarking engine is applied to the registered 3D localizer image to yield one or more updated landmarks. A plurality of reference points for performing a MR scan are computed based on the one or more updated landmarks.

Abstract: A method for detecting and creating magnetic resonance imaging anatomical outlines of a subject, including acquiring magnetic resonance imaging signals of a selected region of interest of the subject's anatomy, processing the magnetic resonance imaging signals to determine image pixel intensity. calculating a mean intensity value associated with the center location of the selected region of interest, and determining concentric interior and exterior anatomical outlines surrounding the center location. Image pixels with an intensity value greater than the mean intensity value by a first threshold amount are designated as part of the interior anatomical outline. Image pixels with an intensity value less than the mean intensity value by a second threshold amount are designated as part of the exterior anatomical outline.

Abstract: Information extracted from sequential images captured from the perspective of a distal end of a medical device moving through an anatomical structure are compared with corresponding information extracted from a computer model of the anatomical structure. A most likely match between the information extracted from the sequential images and the corresponding information extracted from the computer model is then determined using probabilities associated with a set of potential matches so as to register the computer model of the anatomical structure to the medical device and thereby determine the lumen of the anatomical structure which the medical device is currently in. Sensor information may be used to limit the set of potential matches. Feature attributes associated with the sequence of images and the set of potential matches may be quantitatively compared as part of the determination of the most likely match.

Abstract: A device for treating an aneurysm of a human or mammal patient, wherein the aneurysm may self-expand, leading to the aneurysm bursting with high risk for death of the human or mammal patient. The device comprising an implantable member adapted to be placed in connection with the outside of a blood vessel having the aneurysm, and to exercise a pressure on the outside of the blood vessel having the aneurysm, a measuring device or sensor for measuring or sensing an expansion of the aneurysm, and a pressure regulator adapted to regulate the exercised pressure on the outside of the blood vessel having the aneurysm.

Abstract: The disclosure relates to devices, systems and methods for detecting markers in breath, more specifically volatile and non-volatile markers associated with pulmonary diseases such as, for example, asthma, chronic obstructive pulmonary disease (COPD), or cystic fibrosis (CF), in exhaled breath condensate (EBC).

Abstract: Methods of and devices for detecting a measurable characteristic of the gas sample. The methods and devices are able to detect a value of or a change of measurable characteristic (e.g., such as chemical concentrations), a change of chemical compositions and/or biological responses of a living organism that are induced by a stressor. The biological responses are able to include cellular stress, damage, and immune responses. The stressor is able to include an exposure to ionizing radiation. The effects of the stressors are able to be monitored in terms of changes in the chemical concentrations and chemical compositions in an exhaled breath. The chemicals are able to function as bio-markers. The chemicals that are to be monitored are able to include nitric oxide, carbon monoxide, carbon dioxide, ethane, and other molecules related to specific disease resulting from the stressor.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: Disclosed are methods, apparatuses, etc. for determination and application of a metric for assessing a patient's glycemic health. In one particular implementation, a computed metric may be used to balance short-term and long-term risks associated with a particular therapy.

Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the first and second measurement portions.

Abstract: Systems, methods and devices for reducing noise in health monitoring including monitoring systems, methods and/or devices receiving a health signal and/or having at least one sensor for health monitoring.

Abstract: An enhanced SPO2 measuring device which includes an optical SPO2 measurement subsystem, an RF SPO2 measurement subsystem, and an integration module that provides at least one of the following functions: a fusion module in which the optical data and RF data are fused to create new SPO2 data: a machine learning module that enhances the final SPO2 measurements; or an accuracy module that provides more accurate SPO2 data.

Abstract: Some embodiments described herein relate to a sensor that includes a first a first polymer-luminescent sensing compound configured to produce a first luminescent signal in the presence of a first analyte and a second polymer-luminescent sensing compound configured to produce a second luminescent signal in the presence of a second analyte. The second luminescent signal can have a luminescent lifetime that is at least 1.1 times greater than a luminescent lifetime of the first luminescent signal. Such temporally differences in signal can be used to deconvolute the first luminescent signal from the second luminescent signal even when, for example, the first luminescent signal and the second luminescent signal have the same or a similar emission spectrum.