Patents Issued in March 28, 2024
  • Publication number: 20240101471
    Abstract: Provided is a tempered glass sheet that has a softening point lower than that of conventional lithium aluminosilicate glass, exhibits excellent thermal bending moldability, and is not easily broken when dropped. Also provided is a method for manufacturing the tempered glass sheet. The tempered glass sheet of the present invention is characterized in that the tempered glass sheet includes, as a glass composition in terms of mol %, from 45 to 70% of SiO2, from 9 to 25% of Al2O3, from 0 to 10% of B2O3, from 4 to 15% of Li2O, from 1 to 21% of Na2O, from 0 to 10% of K2O, from 0.03 to 10% of MgO, from 0 to 10% of ZnO, from 0 to 15% of P2O5, and from 0.001 to 0.30% of SnO2, and the tempered glass sheet satisfies [Li2O]+[Na2O]+[K2O]?15%, and ([Li2O]+[Na2O]+[K2O]+[ZnO])/[Al2O3]?1.1.
    Type: Application
    Filed: February 1, 2022
    Publication date: March 28, 2024
    Inventor: Ken YUKI
  • Publication number: 20240101472
    Abstract: Provided is a method of manufacturing a window, which includes preparing a first preliminary glass substrate including Li+ ions and Na+ ions, providing a first strengthening molten salt including Na+ ions onto the first preliminary glass substrate and forming a second preliminary glass substrate, providing a second strengthening molten salt including Rb+ ions onto the second preliminary glass substrate and forming a third preliminary glass substrate, and providing a third strengthening molten salt including K+ ions onto the third preliminary glass substrate and forming a strengthened glass substrate.
    Type: Application
    Filed: July 19, 2023
    Publication date: March 28, 2024
    Applicant: Samsung Display Co., Ltd.
    Inventors: WON-JONG BAEK, TAEHO AN
  • Publication number: 20240101473
    Abstract: A method for manufacturing a glass plate includes processing for irradiating an inner circumferential edge surface extending along an inner hole in an annular glass plate with a laser beam along the inner circumferential edge surface. When the inner circumferential edge surface is irradiated with the laser beam, the laser beam is concentrated by a condenser lens and formed into diffused light, and the inner circumferential edge surface is irradiated with the diffused light from a direction inclined with respect to a main surface of the glass plate.
    Type: Application
    Filed: January 28, 2022
    Publication date: March 28, 2024
    Inventor: Shuhei AZUMA
  • Publication number: 20240101474
    Abstract: A resin composition for primary coating of an optical fiber contains a photopolymerizable compound containing a urethane (meth)acrylate containing a reaction product of a polypropylene polyol having a number average molecular weight of 8000 or more and 20000 or less and an isocyanate group-containing (meth)acrylate and a photopolymerization initiator.
    Type: Application
    Filed: December 21, 2021
    Publication date: March 28, 2024
    Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.
    Inventor: Yuya HOMMA
  • Publication number: 20240101475
    Abstract: A glass composite includes a first glass member and a second glass member. The first glass member and the second glass member are at least partially connected with each other at the surfaces; and the glass composite has a light transmittance not lower than 95% of the light transmittance of the one, with the lower light transmittance, of the first glass member and the second glass member.
    Type: Application
    Filed: November 30, 2023
    Publication date: March 28, 2024
    Inventors: Lan MA, Liang CHEN, Xiong YUAN, Chen LI
  • Publication number: 20240101476
    Abstract: An apparatus for production of burnt lime or dolomite has: a shaft furnace having a preheating zone, a reaction zone, a separation zone and a cooling zone; a first feed apparatus for CO2 at the boundary of the separation zone to the reaction zone; a first removal apparatus at the boundary of the cooling zone to the separation zone; a second removal apparatus for CO2 at the start of the preheating zone; and at least one heating apparatus, wherein the heating apparatus has a regenerator system. The regenerator system has at least two regenerators, a preheater, a feed for fuel and a feed for fresh air; the second removal apparatus opens into the at least one heating apparatus; and the first feed apparatus is formed by the at least one heating apparatus for the shaft furnace.
    Type: Application
    Filed: August 28, 2023
    Publication date: March 28, 2024
    Inventors: Tino REDEMANN, Gerrit DOMBROWSKI, Henning WEBER
  • Publication number: 20240101477
    Abstract: A method of calcining a clay material for use as a supplementary cementitious material, includes providing a raw clay material, optionally drying the raw clay material, granulating the raw clay material in order to obtain raw clay granules, calcining the raw clay granules to obtain calcined clay granules, and grinding the calcined clay granules to obtain a pulverulent supplementary cementitious material.
    Type: Application
    Filed: December 14, 2021
    Publication date: March 28, 2024
    Inventors: Thomas DURAND, Pascal DION
  • Publication number: 20240101478
    Abstract: A 100% solids composition and method for priming or sealing a concrete surface wherein the 100% solids composition is formed of a tree rosin ester resin and a vegetable oil or vegetable oil-derived plasticizer, which are renewable or largely renewable, and wherein the 100% solids composition provides strong adhesion, can be applied by brushing or spraying at a temperature of less than 400° F. without adding a solvent or water thereto, produces substantially no VOCs, requires no time for curing or evaporation, and is ready for traffic or other normal use after cooling.
    Type: Application
    Filed: September 20, 2023
    Publication date: March 28, 2024
    Inventors: Christopher Shane Kinder, Joseph Drbohlav, III, Brian J. Majeska, Joseph J. Jorenc
  • Publication number: 20240101479
    Abstract: A method of making a setting type compound by injecting an activator compound into a plaster compound wherein the activator compound tube is coaxial and within the plaster compound tube, each at the same flowrate, the same pressure and the same viscosity. The cross sectional transverse areas of an annulus containing the plaster compound and the hole in the annulus containing the activator compound are the same.
    Type: Application
    Filed: April 6, 2023
    Publication date: March 28, 2024
    Applicant: UNITED STATES GYPSUM COMPANY
    Inventors: Rafael Bury, Joseph W. Schlude, David D. Pelot, Naveen Punati, Tyler Kincaid, Juan Ignacio Huitzil
  • Publication number: 20240101480
    Abstract: Nanomaterial ceramic spheres, a preparation method, and an application thereof are provided. The raw materials of the nanomaterial ceramic spheres include 1-30 parts of nano-titanium dioxide, 1-30 parts of nano-zirconia, 1-30 parts of nano-tourmaline, and 1-30 parts of kaolin. In the present invention, mixing a first part of kaolin with water, rubbing it into soft spheres, and baking to obtain sphere cores; mixing a second part of kaolin, nano-titanium dioxide, nano-zirconia, and nano-tourmaline and performing a pre-mixing to obtain a pre-mixed material; mixing the sphere cores, water, an adhesive, and the pre-mixed material and rubbing into rounds to obtain a nanomaterial; baking the nanomaterial to obtain the nanomaterial ceramic spheres. The nanomaterial ceramic spheres significantly improve fuel combustion efficiency and meet the functional requirements of energy conservation.
    Type: Application
    Filed: November 30, 2022
    Publication date: March 28, 2024
    Inventor: WEI-LING KUO
  • Publication number: 20240101481
    Abstract: A composition comprises a zirconia powder, in which 55% or more thereof is monoclinic, and a stabilizer capable of suppressing phase transition of zirconia. An average particle diameter of zirconia particles and particles of the stabilizer is 0.06 ?m to 0.17 ?m. At least a portion of the stabilizer does not form a solid solution with zirconia.
    Type: Application
    Filed: December 1, 2023
    Publication date: March 28, 2024
    Applicant: KURARAY NORITAKE DENTAL INC.
    Inventor: Yoshihisa ITO
  • Publication number: 20240101482
    Abstract: Provided is a stabilized zirconia sintered body which comprises a fluorescent agent containing zirconium and titanium, and shows fluorescence when irradiated with light including light of a wavelength of 250 nm to 380 nm.
    Type: Application
    Filed: January 12, 2021
    Publication date: March 28, 2024
    Applicant: DAIICHI KIGENSO KAGAKU KOGYO CO., LTD.
    Inventors: Masayuki TAKAI, Keita KANENISHI
  • Publication number: 20240101483
    Abstract: To provide at least one of: a powder composition from which a calcined body with similar processability can be produced without requiring the application of different forming conditions and calcination conditions for each composition; a method for producing the powder composition; a calcined body produced from the powder composition; a method for producing the calcined body; and uses thereof. A powder composition including: two or more types of zirconia in which a lanthanoid rare-earth element is dissolved; a transition metal element other than zirconium and hafnium; and a remainder composed of zirconia stabilized only by one or more selected from the group consisting of yttrium, calcium and magnesium, wherein a different lanthanoid rare-earth element is dissolved in each zirconia in which the lanthanoid rare-earth element is dissolved, and a transition metal element content is 1500 ppm or less.
    Type: Application
    Filed: January 19, 2022
    Publication date: March 28, 2024
    Applicant: TOSOH CORPORATION
    Inventors: Sho AZECHI, Yuki USHIO, Takahiro SHIMIZU, Yuya HIGUCHI, Hitoshi NAGAYAMA, Hiroyuki FUJISAKI, Kenji IMAI, Risa KAWASHIMA
  • Publication number: 20240101484
    Abstract: A ceramic matrix composite includes, as a matrix, boron carbide, silicon carbide, and metal silicon or a silicon alloy. The boron carbide is contained as a main component of the matrix.
    Type: Application
    Filed: January 26, 2021
    Publication date: March 28, 2024
    Applicant: Mitsubishi Electric Corporation
    Inventors: Masami KUME, Yohei ITO
  • Publication number: 20240101485
    Abstract: A powder composition includes a first powder, a second powder, and a modified functional group. A particle size range of the first powder is between 1 micron and 100 microns. The second powder and the modified functional group are modified on the first powder. A particle size range of the second powder is between 10 nanometers and 1 micron. A manufacturing method of a powder composition is also provided.
    Type: Application
    Filed: November 15, 2022
    Publication date: March 28, 2024
    Applicant: NAN YA PLASTICS CORPORATION
    Inventors: Te-Chao Liao, Hung-Yi Chang, Chia-Lin Liu
  • Publication number: 20240101486
    Abstract: Disclosed herein is a multilayer sintered ceramic body comprising at least one first layer comprising poly crystalline YAG, wherein the at least one first layer comprising poly crystalline YAG comprises pores wherein the pores have a maximum size of from 0.1 to 5 ?m, at least one second layer comprising alumina and zirconia wherein the zirconia comprises at least one of stabilized and partially stabilized zirconia, and at least one third layer comprising at least one of YAG, alumina, and zirconia, wherein an absolute value of the difference in coefficient of thermal expansion (CTE) between the at least one first, second and third layers is from 0 to 0.75×10-6/° C. as measured in accordance with ASTM E228-17, wherein the at least one first, second and third layers form a unitary, multilayer sintered ceramic body. Methods of making are also disclosed.
    Type: Application
    Filed: December 17, 2021
    Publication date: March 28, 2024
    Inventors: Luke WALKER, Matthew Joseph DONELON, Saurabh WAGHMARE, Lillan THOMPSON
  • Publication number: 20240101487
    Abstract: The present invention provides a storage stable silicon-containing powder composition suitable for use in dry mix compositions containing cement and filler suitable as cement-based tile adhesives, the powder composition comprising (i) a water redispersible polymer powder (RDP); and, (ii) a granular composition of (a) a silicate carrier, (b) a polydiorganosiloxane, (c) a hydrolysable silane containing a C4 to C12 alkyl group, or an oligomer thereof, and (d) a polymer encapsulant for the hydrolysable silane and the polydiorganosiloxane, wherein the weight ratio of the total RDP to the total weight of granular composition ranges from 90:10 to 98:2. The present invention provides methods of using dry mixes as cement-based tile adhesives wherein the powder composition enables good open time and excellent tensile adhesion, especially after heat aging.
    Type: Application
    Filed: April 13, 2022
    Publication date: March 28, 2024
    Inventors: Elodie Hablot, Margarita Perello, Jean-Paul Lecomte
  • Publication number: 20240101488
    Abstract: A superhydrophobic asphalt and a method of its preparation. The superhydrophobic asphalt contains an asphalt layer containing a polymer modified asphalt, preferably a radial SBS modified asphalt, and a polypropylene layer. The polypropylene layer comprises granules of polypropylene thermally fused to the asphalt layer. The superhydrophobic asphalt has a water contact angle of 145 to 170°, above the classification threshold for superhydrophobicity. The method of preparing the superhydrophobic asphalt involves distributing polypropylene granules over the surface of a polymer modified asphalt and curing below the melting temperature of the polypropylene. The asphalt may find use in waterproofing applications such as roofing.
    Type: Application
    Filed: November 28, 2023
    Publication date: March 28, 2024
    Applicant: Imam Abdulrahman Bin Faisal University
    Inventor: Muhammad Abubakar DALHAT
  • Publication number: 20240101489
    Abstract: The present disclosure describes compositions that include ferrihydrite (Fh) and methods of using such compositions to improve the growth of plants.
    Type: Application
    Filed: September 15, 2023
    Publication date: March 28, 2024
    Inventors: Arindam Malakar, Daniel Snow, Chittaranjan Ray
  • Publication number: 20240101490
    Abstract: A process of chemical cleavage of leather or skins containing chromium The process using sodium, potassium or calcium methylates (CH3O?) or ethylates (CH3CH2O?), producing chromium hydroxide (green paste), ammonium sulfate and liquid fertilizer. The chromium trioxide III (Cr2O3) obtained was used in the production of Fe—Cr alloy. The liquid fertilizer was applied to strawberry, violet and acerola crops, and can be applied to other types of crops. The fertilizer is also compatible with pesticides, being able to compose a composition containing fertilizer and pesticide or even used to obtain products containing fertilizers and pesticides, which allow application in a single step, exempting the process in the field A solid NPK fertilizer formulation obtained by combining N recovered from waste and homogeneously mixed with K and P salts.
    Type: Application
    Filed: August 28, 2020
    Publication date: March 28, 2024
    Inventors: Luiz Carlos ALVES DE OLIVEIRA, Jadson Claudio BELCHIOR, Adilson CANDIDO DA SILVA, Marcio DE FIGUEIREDO PORTILHO
  • Publication number: 20240101491
    Abstract: The present invention adopts a microbial preparation production method comprising: a step for mixing crushed waste gypsum with a culture medium containing microorganisms to obtain a mixed liquid; and a step for culturing the mixed liquid. The particle diameter of the crushed waste gypsum is at most 30 mm.
    Type: Application
    Filed: November 30, 2023
    Publication date: March 28, 2024
    Inventors: Yohei ISHIDA, Tamaki GOTO, Katsuhiko FUJII, Toshinori OKURA
  • Publication number: 20240101492
    Abstract: Synthetic compositions comprising a plant element and at least one fungal endophyte are described. The fungal endophyte is capable of improving plant tolerance to biotic stress as compared to a reference plant element not further comprising the endophyte. Examples of biotic stress include the biotic stress caused by a nematode, an aphid, a fleahopper, a Lygus bug, a stink bug, a soy looper, a cabbage looper, or a fungus.
    Type: Application
    Filed: September 12, 2023
    Publication date: March 28, 2024
    Inventor: Gregory A. SWORD
  • Publication number: 20240101493
    Abstract: The present subject matter is directed to a coconut coir product comprising coconut coir having some values for electrolytes of interest in a range as measured by photoelectric flame photometry, or flame emission spectroscopy, or inductively coupled plasma atomic emission spectroscopy (ICP-AES).
    Type: Application
    Filed: October 31, 2022
    Publication date: March 28, 2024
    Inventors: Pazhanimuthu Annamalai, Satheesh Rao
  • Publication number: 20240101494
    Abstract: The present invention relates to improving the efficacy of man-made and/or natural organic-based animal manure fertilizers by administration of an organic solvent formula containing polyorganic acids and/or their salts. The formulation liberates nutrient(s) that are normally bound in the soil as insoluble salts and complexes. These delivery formulations also provide an environmentally sound and inherently safe solvating system that improves diffusion of polyorganic acids to the granule fertilizer. These delivery formulations enable safe storage, transport and subsequent application or blending with solid or liquid fertilizers. The combined formulation and fertilizer can be applied to soil to provide improved efficacy of fertilizer by liberating nutrients bound in the soil for uptake by plant life.
    Type: Application
    Filed: December 6, 2023
    Publication date: March 28, 2024
    Inventors: Gary David McKnight, Randall Linwood Rayborn
  • Publication number: 20240101495
    Abstract: A solubilizing composition that facilitates solubilizing fertilizer compounds and/or fertilizer compositions when in an aqueous solution particularly in an in-furrow application. The solubilizing composition includes a first anionic surfactant and a first and second humectant.
    Type: Application
    Filed: October 12, 2020
    Publication date: March 28, 2024
    Inventors: Paulo Sergio BERG, Melvin Donovan PULLEN, Jared VANDERZYL
  • Publication number: 20240101496
    Abstract: The present invention relates to a novel mixture of nitrification inhibitors comprising (i) an alkoxypyrazole compound of formula (I) or a salt, tautomer, or N-oxide thereof, and (ii) dicyandi-amide (DCD), in a weight ratio of from 100:1 to 1:100. Moreover, the invention relates to the use of the mixture of the invention, methods of applying the mixture of the invention, and to agrochemical mixtures and compositions comprising the mixture of the invention.
    Type: Application
    Filed: February 2, 2022
    Publication date: March 28, 2024
    Inventors: Alexander Wissemeier, Wolfgang Weigelt, Barbara Nave
  • Publication number: 20240101497
    Abstract: A method for producing an olefin product, including the steps of converting a hydrocarbon feedstock to an unsaturated hydrocarbon stream through a steam cracking process in an olefins production plant; combusting hydrogen to provide at least some of the heating duty to the steam cracking process, wherein the hydrogen has a carbon intensity less than about 1.0 kg CO2e/kg H2, wherein the hydrogen is produced using a hydrogen production process; providing at least some of the required energy for the hydrogen production process from a biomass power plant; and processing the unsaturated hydrocarbon stream to recover the olefin product. The olefin product may comprise ethylene having a well-to-gate carbon intensity less than about 0.6 kg CO2e/kg C2H4, or may comprise propylene having a well-to-gate carbon intensity less than about 0.6 kg CO2e/kg C3H6.
    Type: Application
    Filed: September 25, 2023
    Publication date: March 28, 2024
    Inventors: Christopher Michael MILLER, Gregory David SMITH, Anna Louise BUCKLEY, Byron Gladus BEST, III, Bengt Arne JARLSJO, Dainel Joseph SHAPIRO
  • Publication number: 20240101498
    Abstract: This disclosure relates to processes which involve: contacting a mixture comprising at least one fluoroolefin and at least one impurity with at least one zeolite to reduce the concentration of the at least one impurity in the mixture; and the at least one zeolite is selected from the group consisting of zeolites having pore opening of at least 4 Angstroms and no more than about 5 Angstroms, zeolites having pore opening of at least about 5 Angstroms and Sanderson electronegativity of no more than about 2.6, and mixtures thereof; provided that the at least one zeolite is not zeolite 4A. This disclosure also relates to processes for making at least one hydrotetrafluoropropene product selected from the group consisting of CF3CF?CH2, CF3CH?CHF, and mixtures thereof; and relates to processes for making at least one hydrochlorotrifluoropropene product selected from the group consisting of CF3CCl?CH2, CF3CH?CHCl, and mixtures thereof.
    Type: Application
    Filed: December 4, 2023
    Publication date: March 28, 2024
    Inventors: Mario Joseph NAPPA, Xuehui SUN, David Richard CORBIN
  • Publication number: 20240101499
    Abstract: The present invention relates to a Si/Al zeolite catalyst with cubical morphology, having pore diameter in the range of 0.5 to 0.6 ?m, pore volume in the range of 0.2 to 0.3 cc/g, surface area in the range of 500 to 700 m2/g, and SiO2/Al2O3 ratio in the range of 30 to 200. The present invention also relates to a process for its preparation and its application in one step, one pot synthesis of ether.
    Type: Application
    Filed: January 14, 2022
    Publication date: March 28, 2024
    Inventors: Vijay Vasant BOKADE, Sachin Uttamrao NANDANWAR, Prashant Suresh NIPHADKAR
  • Publication number: 20240101500
    Abstract: A system and method of regenerating triethylene glycol (TEG) in natural gas dehydration, including removing water from TEG in a TEG regeneration still column having a fired-heater reboiler that includes a burner and a reboiler vessel. The TEG bath temperature in the reboiler vessel and the oxygen gas content in a stack effluent from the burner are controlled automatically via a control system adjusting flow of air and fuel to the burner while maintaining a specified weight ratio of the air to the fuel.
    Type: Application
    Filed: December 1, 2023
    Publication date: March 28, 2024
    Inventor: Abdullah Y. Al-Aiderous
  • Publication number: 20240101501
    Abstract: The present disclosure relates to a process for the preparation of ethyl tert-butyl ether comprising: (a) reacting ethanol with a mixture of C4 hydrocarbon feed in the presence of a catalyst to obtain a mixture; and (b) contacting the mixture with an entrainer at a temperature in the range of 40-70° C. and a pressure in the range of 15-30 bars to obtain ethyl tert-butyl ether, wherein, the mixture of C4 hydrocarbon feed comprises isobutylene, and the ethanol to isobutylene mole ratio is in the range of 1:1 to 2:1. The present disclosure also discloses a process of separating ethanol and ethyl tert-butyl ether. Further, the present disclosure discloses a composition comprising ethyl tert-butyl ether with a purity in the range of 91%-93%.
    Type: Application
    Filed: March 17, 2021
    Publication date: March 28, 2024
    Applicant: HINDUSTAN PETROLEUM CORPORATION LIMITED
    Inventors: Santhoshkumar Reddy SANDIRI, Bennet CHELLIAHN, Valavarasu GNANASEKARAN, Ramachandra Rao BOJJA
  • Publication number: 20240101502
    Abstract: A production method of one or both of (meth)acrolein and (meth)acrylic acid using a heat-exchange-type reaction vessel having a reaction tube at an inner part is provided, the method including causing an oxidation reaction of a raw material supplied to the reaction tube while circulating a heat medium to an outer side of the reaction tube to produce one or both of (meth)acrolein and (meth)acrylic acid, in which the reaction tube has i layers, which are a plurality of catalyst layers having different catalyst charging amounts per unit volume, in a longitudinal direction of the reaction tube, provided that i is an integer of 2 or more, and the oxidation reaction satisfies Expression (1). ??0.275(mol·K·h?1·W?1)??(1) Provided that (AAA) is satisfied. ?=F×(m1/?j=1imj)/(U×A). . .
    Type: Application
    Filed: November 21, 2023
    Publication date: March 28, 2024
    Applicant: Mitsubishi Chemical Corporation
    Inventor: Keisuke Baba
  • Publication number: 20240101503
    Abstract: The present invention relates to a process for the preparation of diverse known and novel cannabinoids 5, which include cannabigerol (CBG, 1), cannabigerolic acid (CBGA, 2), cannabigerovarin (CBGV, 3), cannabigerovarinic acid (CBGVA, 4) and other naturally occurring monocyclic cannabinoids and other analogues from simple inexpensive starting materials using a cascade sequence of allylic rearrangement and aromatization. Novel cannabinoids of series 5 are also claimed as part of the invention. These synthesized cannabinoids, unlike the minor cannabinoids isolated from Cannabis saliva or synthesized from the condensation reactions such as the reactions of substituted resorcinols with monoterpenes, are much easier to obtain at high purity levels. In particular, these cannabinoids, including but not limited to cannabigerol (CBG, 1), cannabigerolic acid (CBGA, 2), cannabigerovarin (CBGV, 3) and cannabigerovarinic acid (CBGVA, 4) are obtained without contamination with impurities with variation in RA and RB (e.g.
    Type: Application
    Filed: October 7, 2020
    Publication date: March 28, 2024
    Inventors: Barry A. Berkowitz, Anthony G. Barrett, Daniel Elliott
  • Publication number: 20240101504
    Abstract: A method for producing a hydroxyalkanoic acid crystal, comprising freeze-drying a solution containing a hydroxyalkanoic acid, wherein based on the total amount of the hydroxyalkanoic acid taken as 100 mass %, (1) the R form content is 95 to 100 mass % or (2) the S form content is 95 to 100 mass %.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 28, 2024
    Inventors: Masayuki SUGIMOTO, Jun TSUBOTA, Sae ISHIKAWA
  • Publication number: 20240101505
    Abstract: This invention relates to Compound 1 (APX3330) salts and esters. The invention also provides compositions comprising a Compound 1 salt or ester. The invention also provides compounds of formula (I) and formula (II) and pharmaceutically acceptable salts thereof. The invention further provides compositions comprising a compound of formula (I) or formula (II), or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier or vehicle. The invention also provides methods for treating or preventing a disease, such as cancer, a liver disorder, an ocular disorder, a cardiovascular disorder, fibrosis, or an inflammatory disorder, comprising administering to a subject in need thereof an effective amount of a Compound 1 salt or ester; or compound of formula (I) or formula (II), or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 28, 2024
    Inventors: Daniela Carmen ONICIU, Maria-Andreea LUNGAN, Andrei-Alunel PATRASCU, Corina-Mihaela MANTA, Anthony CARESTIA, Jon HOUSLEY
  • Publication number: 20240101506
    Abstract: The present invention discloses a continuous process for the synthesis of dimethyl carbonate from methanol and carbon dioxide over a ceria-based mixed metal oxide-silica catalyst formulation in the presence of a dehydrating or water trapping compound (2-Cyanopyridine).
    Type: Application
    Filed: January 25, 2022
    Publication date: March 28, 2024
    Inventors: Darbha SRINIVAS, Vijay Vasant BOKADE, Prashant Suresh NIPHADKAR, Unnikrishnan PULIKKEEL, Snehalkumar PARMAR, Vinay AMTE, Surajit SENGUPTA, Asit Kumar DAS
  • Publication number: 20240101507
    Abstract: A process for synthesizing (S,S) ethylenediamine-N,N?-disuccinic acid (EDDS) includes combing an aqueous solution of aspartic acid with dibromoethane under basic conditions to form a reaction solution; heating the reaction solution to form a heated reaction solution, and recovering at least a portion of the reaction product from the reaction solution. The heated reaction solution comprises a reaction product, wherein the reaction product comprises (S,S) ethylenediamine-N,N?-disuccinic acid (EDDS).
    Type: Application
    Filed: February 3, 2022
    Publication date: March 28, 2024
    Inventors: Ian M. KLEIN, Daniel MORGAN, Eric MCFARLAND, Mahdi M. ABU-OMAR
  • Publication number: 20240101508
    Abstract: The present invention relates to a method for preparing an isocyanate compound. According to the present invention, provided is a method for preparing an isocyanate compound that can minimize thermal denaturation of a reaction product and formation of by-products and obtain a high-purity isocyanate compound during the preparation of an isocyanate compound using phosgene.
    Type: Application
    Filed: December 30, 2021
    Publication date: March 28, 2024
    Inventors: Hyun Cheol RYU, Ju Wu MIN, Keedo HAN
  • Publication number: 20240101509
    Abstract: Disclosed are compounds that can penetrate the mitochondrial membrane and that are able to deliver cargo (e.g., therapeutic agents) specifically to the mitochondria.
    Type: Application
    Filed: October 31, 2023
    Publication date: March 28, 2024
    Inventors: Dehua PEI, George APPIAH KUBI, Ziqing QIAN
  • Publication number: 20240101510
    Abstract: Disclosed herein are apyrase inhibitors of Formula (I) Also disclosed herein are methods for using the disclosed inhibitors, including in methods for protecting crops from pests. In one aspect the apyrase inhibitors are useful for enhancing the activity of pesticides for the protection of crops from pathogens and to support crop yield.
    Type: Application
    Filed: August 31, 2023
    Publication date: March 28, 2024
    Inventors: Matthew Duncton, Jeffrey D. Fowler, John Clough, Tanya Sabharwal, Simon Hiebert
  • Publication number: 20240101511
    Abstract: A method of producing an organic peroxide includes introducing an organic solution and a peroxide solution into a mixing tank to form a mixture. The method further includes circulating the mixture over a fixed catalyst bed to form the organic peroxide and measuring a concentration of the organic peroxide in the mixture. Further, the method includes removing at least a portion of the mixture when the concentration reaches a set value.
    Type: Application
    Filed: December 7, 2023
    Publication date: March 28, 2024
    Inventors: Todd COLEMAN, Tim YEAMAN, Slaton FRY
  • Publication number: 20240101512
    Abstract: The present application relates to compounds of formula (I), or pharmaceutically acceptable salts thereof: wherein R1 and R2 represent hydrogen or deuterium; R3 represents hydrogen, —COOH or —OH; R3? and R3? represent hydrogen, methyl, methoxy, chlorine, fluorine or cyano; R4 and R41 represent hydrogen or fluorine; R5 represents hydrogen, fluorine or (C1-C3)alkyl; R6 represents phenyl, fused phenyl, bicyclic group comprising 5 to 12 carbon atoms, heteroaryl group comprising 2 to 9 carbon atoms and comprising from 1 to 3 heteroatoms, cycloalkyl group comprising 3 to 7 carbon atoms, (C3-C6)cycloalkyl(C1-C3)alkyl group, 3 to 8 membered-heterocycloalkyl group comprising 1 or 2 heteroatoms, (C1-C6)alkyl, and phenyl(C1-C2)alkyl group; X represents —CH2—, —O— or —S—; Y represents —CH?, —N? or —CR??, wherein R? represents (C1-C3)alkyl, halogen, cyano, or (C1-C3)fluoroalkyl; R7 represents (C1-C3)alkyl, halogen atom, cyano, or (C1-C3)fluoroalkyl; R8 represents hydrogen or fluorine; R9 represents hydrogen, (C1-C3)alkyl
    Type: Application
    Filed: October 19, 2021
    Publication date: March 28, 2024
    Applicant: Sanofi
    Inventors: Patrick Bernardelli, Marc Bianciotto, Youssef El Ahmad, Frank Halley, Patrick Mougenot, Frédéric Petit, Franck Slowinski, Corinne Terrier
  • Publication number: 20240101513
    Abstract: The present invention is directed to novel chemical compositions of matter and their methods of synthesis, and in particular novel analogs of Psilocin having enhanced physical and pharmacokinetic characteristics.
    Type: Application
    Filed: November 1, 2023
    Publication date: March 28, 2024
    Inventors: Denton W. Hoyer, Robert F. Roscow
  • Publication number: 20240101514
    Abstract: Pharmaceutically acceptable salts of 5-methoxy-N,N-dimethyltryptamine are described, as well as compositions/formulations and uses thereof as a medicament.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 28, 2024
    Applicant: BECKLEY PSYTECH LIMITED
    Inventors: Jason GRAY, Susana DEL RIO GANCEDO, Dita DAVIS, David James PEARSON, Daniel RIXSON
  • Publication number: 20240101515
    Abstract: The present invention relates to a chemical synthesis route for preparing 3-nitro-N-(2,2,2-trifluoroethyl)-4-pyridinamine which compound can be used as an intermediate compound in the synthesis of RSV inhibiting imidazopyridines or imidazopyrimidines.
    Type: Application
    Filed: October 29, 2020
    Publication date: March 28, 2024
    Inventors: Hongyu TAN, Licheng HAN
  • Publication number: 20240101516
    Abstract: The presently claimed invention relates to a process for the preparation of mono-, di-, tri-, fluoro arylamide or hetroarylamide.
    Type: Application
    Filed: January 17, 2022
    Publication date: March 28, 2024
    Inventors: Rahul Kaduskar, Kailaskumar Borate, Suyog Adhav, Saravanan Thirunavukkarasu, Harish Shinde, Roland Goetz
  • Publication number: 20240101517
    Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
    Type: Application
    Filed: November 27, 2023
    Publication date: March 28, 2024
    Inventors: Sheng CUI, Henry MORRISON, Karthik NAGAPUDI, Shawn D. WALKER, Charles BERNARD, Karl Bennett HANSEN, Neil Fred LANGILLE, Alan Martin ALLGEIER, Steven MENNEN, Jacqueline C.S. WOO, Bradley Paul MORGAN, Alex MUCI (DECEASED)
  • Publication number: 20240101518
    Abstract: Provided herein is a method for treating a monocarboxylate transporter MCT4-mediated disorder in a subject in need thereof. The method comprises the step of administering to the subject a compound of structural Formula I and/or a salt thereof. The treatment of the monocarboxylate transporter MCT4-mediated disorder may inhibit activity of MCT4, or a mutant thereof, sometimes with at least a 100-fold selevtivity for MCT4 over MCT1.
    Type: Application
    Filed: June 19, 2023
    Publication date: March 28, 2024
    Inventors: Kenneth Mark PARNELL, John MCCALL
  • Publication number: 20240101519
    Abstract: Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, agricultural compositions containing them and their use as herbicides wherein R1, R2, R3, R4, R14, and X are as defined in the disclosure, A is selected from and R12, R13, n, X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, Y and Y1 are as defined in the disclosure.
    Type: Application
    Filed: December 20, 2021
    Publication date: March 28, 2024
    Inventors: Stephen Frederick MCCANN, Thomas Paul SELBY, Thomas Martin STEVENSON, Alison Mary LEVENS
  • Publication number: 20240101520
    Abstract: A method for obtaining a new pyrimethamine polymorph, wherein an intermediate a-{4-chlorophenyl)-2-ethyl-1,3-dioxalon-2-acetonitronyl is obtained by means of a reaction with ethylene glycol, and recrystallization is carried out in the presence of dioxane.
    Type: Application
    Filed: August 6, 2020
    Publication date: March 28, 2024
    Inventors: Abrham Alberto GUTIÉRREZ HERNÁNDEZ, Aarón RODRÍGUEZ WELTON