Abstract: An electrode formed by molding a semiconductor device with resin. The electrode comprises: a first resin mold portion formed on a front surface of the semiconductor device and having a first thickness (t1); a second resin mold portion formed on a back surface of the semiconductor device and having a second thickness (t2) greater than the first thickness; and an exposed portion formed in a part of the first resin mold portion corresponding to an end of the semiconductor device.

Abstract: A method of forming a glass electrochemical sensor is described. In some embodiments, the method may include forming a plurality of electrical through glass vias (TGVs) in an electrode substrate; filling each of the plurality of electrical TGVs with an electrode material; forming a plurality of contact TGVs in the electrode substrate; filling each of the plurality of contact TGVs with a conductive material; patterning the conductive material to connect the electrical TGVs with the contact TGVs; forming a cavity in a first glass layer; and bonding a first side of the first glass layer to the electrode substrate.

Abstract: There is provided a method of producing a gas sensor element capable of detecting a concentration of specific ions based on a limiting current passing between a first electrode and a second electrode according to a concentration difference of the specific ions. The method includes a temperature raising step, a current measuring step and a control step. In the temperature raising step, a heater is energized to raise temperature of a solid electrolyte. In the current measuring step, a voltage is applied across the first and second electrodes and to measure a limiting current. In the control step, a part of a diffusion resistance layer is removed from the gas sensor element by using an ultrashort pulsed laser to control a diffusion length that is a length of an introduction path to maintain the limiting current to be within a final standard range.

Abstract: A device for base calling is provided. The device includes a receptacle configured to hold a biosensor having a sample surface holding a plurality of clusters during a sequence of sampling events, an array of sensors sensing information from clusters disposed in corresponding pixel areas of the sample surface during the sampling events and generate sequences of pixel signals and a communication port configured to output the sequences of pixel signals. The device also includes a signal processor coupled to the communication port and configured to receive and process at least one pixel signal in the sequences of pixel signals that mixes light gathered from at least two clusters in a corresponding pixel area, and to base call each of the at least two clusters using the at least one pixel signal.

Abstract: To provide a zeta-potential measurement jig which does not require dedicated tools and enables placement of a sample in a cell with simple work. Provided is a zeta-potential measurement jig, to be used for an electrophoretic mobility measuring device, including: a frame body including: a first holding wall and a second holding wall; and a bottom wall; an intermediate block, and a cell retainer, wherein at least one of the first holding wall or the second holding wall has one of a first groove or a first protrusion to be elastically fitted into the first groove, which is configured to support the intermediate block on a lateral side, and wherein the intermediate block has another one of the first groove or the first protrusion.

Abstract: Methods and apparatus for ion accumulation are disclosed. An apparatus for ion accumulation includes multiple regions. A first region receives and transfers ions to a second region using a first drive potential. The second region is switchable between a first state where it generates a first electric field preventing ions from further movement and entering a third region, and a second state where it generates a second electric field that guides the ions toward the third region. When in the first state, the ions are prevented from further movement by the first electric field, which causes the ions to accumulate in the second region. When in the second state, the ions are moved from the second region to the third region by the second electric field. A method of accumulating ions involves switching an electric field applied to a region between a trap state and a release state.

Abstract: A gas concentration detection device includes: a gas concentration sensor having a gas sensor element that outputs an electric signal according to a gas concentration and a heater that heats the gas sensor element; a heater controller controlling energization and de-energization of the heater; a sensor controller having an ADC AD-converting the electric signal from an analog signal to a digital signal in synchronization with a sampling clock (fs) and detecting the gas concentration based on an output signal of the AD converter; and a timing adjuster shifting a switching timing of energization control from a conversion timing at which the AD converter performs the AD conversion.

Abstract: According to various, but not necessarily all, embodiments there is provided an apparatus comprising means for: controlling one or more electroacoustic transducers of a device to create a standing wave having a displacement antinode at an expected location of a component of the device; receiving a signal representing sound generated by vibration of the component driven by the standing wave; causing analysis of the signal to determine whether there is a defect based on whether the signal represents a sound that would be expected to result from vibration of the component driven by the standing wave in the absence of a defect.

Abstract: A fluid measuring device for determining at least one characteristic property of a fluid includes a measuring tube having a fluid duct and a measuring section in which the measuring tube is cylindrical on the inside and an area of a measuring tube wall is configured as a waveguide, and a transmitter for exciting acoustic waves in the waveguide and a receiver for receiving acoustic waves which are in direct contact with an outer surface of the waveguide, wherein acoustic waves excited by the transmitter are adapted to propagate as a volume wave through the fluid. The waveguide has an elongated waveguide path which extends at an acute angle to a longitudinal extension direction of the measuring tube and with a component in the circumferential direction, wherein in the area of the waveguide path, the measuring tube wall has a smaller wall thickness than in areas adjoining the waveguide path.

Abstract: A funnel control device is fixed on a shear box or respective cells in various soil mechanics/dynamics testing devices, and the funnel control device enables to produce soil samples to be tested by discharging a soil through a funnel into a sample preparation mold at a given axis and rate. The funnel control device includes at least one supporting body for being placed on the soil mechanics/dynamics testing device, at least one holder, wherein the at least one holder is provided on the at least one supporting body to be movable in vertical axis and the funnel is placed on the at least one holder, at least one driving member, wherein the at least one driving member is located in or on the at least one supporting body and is used for moving the at least one holder in the vertical axis.

Abstract: A system and method for evaluating a bond is provided. The system uses an underwater spark discharge to generate a compression wave in a first vessel containing a liquid. The system further includes a second vessel in which a vacuum is pulled to hold the first vessel against a bonded structure being inspected. The compression wave is directed to propagate from the liquid into the bonded structure to apply a known force to the bond being inspected.

Abstract: A system for component interconnection for use in liquid chromatography includes a first switching valve and a second switching valve. A first connecting line fluidly connects the first switching valve to the second switching valve. A second connecting line fluidly connects the first switching valve to the second switching valve. A metering device is located in the first connecting line.

Abstract: A circulation device causes gas to circulate between a sample storage space and a temperature adjustment space through the first and second opening regions in a separating member. A temperature of gas flowing in the temperature adjustment space is adjusted by a heat exchanger, so that the temperature of gas surrounding a sample in the sample storage space is adjusted. The separating member further has first and second unit regions. The second opening region includes a first portion located in the first unit region and a second portion located in the second unit region. The shortest distance between the first portion and the first opening region is larger than the shortest distance between the second portion and the first opening region, and an aperture ratio of the first portion in the first unit region is larger than an aperture ratio of the second portion in the second unit region.

Abstract: An injection valve switches between a first state in which a sample loop is connected to a separation flow path through which a mobile phase from a liquid sender flows and a second state in which the sample loop is disconnected from the separation flow path. A pump speed determiner, in a case where a sample intake operation by a syringe pump is started immediately after the injection valve is switched from the second state to the first state, and a filling operation of filling the sample loop with the sample by the syringe pump is started after the intake operation is completed, determines an intake operation speed of the syringe pump that is required in order for the filling operation to complete immediately before the injection valve is switched from the second state to the first state next time using a set injection interval time. The syringe pump operates at the intake operation speed determined by the pump speed determiner while performing the intake operation.

Abstract: An absorbance detector includes a sample cell, a light source for irradiating the sample cell, a photo sensor, an optical system for guiding light emitted from the light source to the sample cell and guiding light that has been transmitted through the sample cell to the photo sensor, a reference signal acquirer configured to acquire a detection signal of the photo sensor when the sample solution is not flowing through the sample cell as a reference signal for each analysis of the sample, a calculator configured to find absorbance of the sample based on a measurement signal obtained by the photo sensor in the analysis and the reference signal acquired for the analysis when an analysis of the sample is carried out, and an analysis data storage configured to associate data of the absorbance found by the calculator and data of the reference signal to each other for storage.

Abstract: A deflection-type refractometer with extended measurement range having a light source generating a beam of light; a measuring cell with a sample chamber receiving a sample liquid; an optical sensor mounted on a movable platform for detecting the deflected beam of light; a driving unit configured to move the platform; a distance measurement unit for monitoring the displacement of the platform; a control unit configured to calculate the deflection of the beam of light based on the displacement of the platform and an output signal of the optical sensor to obtain a refractive index measure of the sample liquid using the calculated deflection.

Abstract: The present application discloses method and sewer (111) for detecting faults associated with a gas chromatograph device (100) in a process plant. The gas chromatograph device (100) is associated with a database (110) configured to store a measured chromatogram, and historic chromatograms. Initially, the server receives the measured chromatogram from the database. Upon receiving the measured chromatogram, the server is configured to detect at least one real-time symptom for measured chromatogram. The real-time symptoms may be detected by comparing the historic chromatograms with predetermined configuration data to the measured chromatogram. Upon detecting the real-time symptoms, the server is configured to determine faults associated with the gas chromatograph device. The faults are determined by mapping the real-time symptoms and fault signature data received from the database.

Abstract: Each of one or more unknown compounds are separated from a sample over a separation time period. Separated compounds are ionized, producing one or more compound precursor ions for each of the unknown compounds and a plurality of background precursor ions. A precursor ion mass spectrum is measured for the combined compound and background precursor ions at each time step of a plurality of time steps spread across the separation time period, producing a plurality of precursor ion mass spectra. One or more background precursor ions are selected from the plurality of precursor ion mass spectra that have a resolving power in a range below a threshold expected resolving power. A separation time is detected for an unknown compound when a decrease in an intensity measurement of the selected background precursor ions over a time period exceeds a threshold decrease in intensity with respect to time.

Abstract: 4-pyrrolylpyridine, a novel anion sensor, displays a substantial color loss upon addition of sodium sulfite in aqueous solvents. A variety of anions were tested, including halides, phosphates, sulfates, and hydroxide, but all solutions remained unchanged aside from the sulfite, which displayed bleaching. Described here is a method for which the exact concentration of sulfites in a consumer product can be determined. The test is sensitive over a broad range of sulfites, from 0.84 ppm to over 10,000 ppm, and is accurate with a standard deviation of ±0.01 ppm.

Abstract: An embodiment provides a method for measuring peracetic acid concentration in an aqueous solution, including: combining, in a reactive solution, 4-(methylthio)aniline and at least one reactive species to produce a chromophore, wherein the at least one reactive species comprises a chromotropic acid disodium salt; placing the chromophore in an aqueous solution, wherein the aqueous solution comprises peracetic acid, wherein peracetic acid within the aqueous solution reacts with the chromophore; and measuring a concentration of peracetic acid within the aqueous solution, wherein the measuring comprises quantifying a colorimetric change of the aqueous solution caused by the peracetic acid reacting with the chromophore. Other embodiments are described and claimed.

Abstract: A method for determining a calibrated measurement value for a concentration of the target gas comprises obtaining a measurement signal based on the concentration of the target gas. The method further comprises determining the calibrated measurement value based on the measurement signal and based on a calibration model. The calibration model is based on calibration data of a plurality of test sensor units having the same type as the sensor unit.

Abstract: Methods of sensing carbon dioxide, sensors, and related articles and systems are generally described.

Abstract: A method determines a potential poisoning of a sensor of an electronic nose by a volatile compound following an exposure of the sensor to a gaseous sample including at least this volatile compound. If there is poisoning, the method determines whether the sensor is still functional such that the sensor is still capable of carrying out one or a plurality of reliable measurements, or on the contrary, whether the sensor is saturated and must no longer be used. The method may be used with any type of electronic nose.

Abstract: A setting method includes setting the conductances of the controllable restrictions of an airborne molecular contamination measurement station. The setting method includes an initial identification step, prior to the carrying-out of an airborne molecular contamination measurement step, and during which the sampling line that has the lowest conductance when the conductance of the controllable restriction of the said sampling line is set to its maximum value is determined, and an initial conductance-setting step prior to the carrying-out of the measurement step and after the initial identification step, and during which the conductances of the controllable restrictions are set to make them correspond to the lowest conductance determined in the initial identification step. Further, a measurement station is provided for measuring airborne molecular contamination.

Abstract: A system for non-invasive microwave testing a bottle of wine may include an emission probe for emitting a microwave signal through a wall of the bottle into the wine and a detection probe for receiving at least a portion of the microwave signal from the wine via the wall.

Abstract: The present invention relates to a sensor (1) for sensing organic carbon in a liquid (L), comprising: a container (2) having an interior space (20) for receiving the liquid (L), a photodetector (3), and a light source (4) configured to emit ultraviolet light (5) so that the ultraviolet light (5) travels along an optical path (P) through liquid (L) residing in the interior space (20) and is absorbable by carbon bonds of organic molecules in the liquid (L).

Abstract: An apparatus for determining total hardness in a fluid stream utilizing a first and second sodium ion selective electrode (ISE). The ion selective electrodes are in electrical communication with one another, having first and second reference electrodes, respectively, with a salt bridge therebetween, where the first ISE receives hard water and the second ISE receives soft water. A least one drain receives outflow from effluent fluid from the first and second sodium ISE sensors.

Abstract: An analytical inspection system for determining concentration of mobile hydrogen of and/or on surfaces of a metallic object can include: a vacuum furnace; a hydrogen sensing device; and/or a flow path from the furnace to the sensing device. The sensing device can be configured to detect and/or measure the mobile hydrogen at levels less than or equal to 1 part per million (ppm). An analytical inspection method for determining concentration of mobile hydrogen of and/or on surfaces of a metallic object can include: placing the object into a vacuum furnace; drawing a vacuum in the furnace; and/or simultaneously heating the metallic object in the furnace and measuring a quantity of the mobile hydrogen released from the object using a hydrogen sensing device. The sensing device can be configured to detect and/or measure the mobile hydrogen at levels less than or equal to 1 ppm.

Abstract: The present invention comprises a test for evaluating spontaneous hydraulic fracturing fluid imbibition and oil displacement method and apparatus utilizing a composite core with a pressurized Amott cell test.

Abstract: An angiosperm index-1 and an angiosperm index-2 are correlated to an age of a liquid hydrocarbon sample and can be used to distinguish oil age of Late Cretaceous (100-65 million years before present, or 100-65 Ma BP) vs. Paleogene (65-55 Ma BP) vs. Eocene or younger (<55 Ma BP). This method improves over existing methods that cannot distinguish oil age between Late Cretaceous and Miocene (ca. 100-5 Ma BP).

Abstract: A detection device that is capable of being attached to a through hole includes a main body portion, a detection portion, a cover portion, an insulation portion, and an oscillation portion. The main body portion has an insertion portion and a head portion. The detection portion is arranged in the insertion portion and detects the state of a fluid. The cover portion is arranged so as to form a gap with the head portion. The insulating portion has a lateral wall having a cylindrical shape. An oscillation portion is accommodated inside the insulation portion, and performs a wireless output of a detection result of the detection portion by using the head portion, the cover portion and the gap as a slot antenna.

Abstract: Systems and methods are provided to simulate, approximate, or replicate conditions similar to concrete elements being placed under pressures equivalent to several hundred feet of ocean water and to provide information useful to assess relative durability of concrete without coring or other destructive actions. The quality of concrete can be assessed by measuring the pressure drop of water or other liquid to ingress through the concrete surface under high pressure over time. A rapid assessment of quality of existing concrete is provided. Systems and methods can efficiently assess long term durability of existing concrete elements such as those used in midrise buildings, parking garages, bridge decks, and the like.

Abstract: The present technology generally relates to a method for modulating in situ production of energy by a biological tissue. The method comprises stimulating the biological tissue by exposing the biological tissue to a photostimulated biophotonic composition for a time sufficient to initiate the production of energy by the biological tissue.

Abstract: A nanopore-based sequencing system includes a plurality of nanopore-based sequencing chips. Each of the nanopore-based sequencing chips comprises a plurality of nanopore sensors. The system comprises at least one flow cell coupled to at least one of the plurality of nanopore-based sequencing chips, wherein the flow cell coupled to the at least one of the plurality of nanopore-based sequencing chips comprises one or more fluidic flow channels that allow a fluid external to the system to flow on top of the nanopore-based sequencing chip and out of the system. The system further comprises a printed circuit board electrically connected to the plurality of nanopore-based sequencing chips.

Abstract: Disclosed are a molecule detection unit, a chip and a preparation method. The molecule detection unit includes a single-hole liquid storage cavity, a liquid resistance flow channel, a buffer flow channel, a sensing electrode, a substrate, a first structural layer, a second structural layer and a sample flow channel. The first structural layer is arranged on the top of the substrate; the single-hole liquid storage cavity and the buffer flow channel are arranged in the first structural layer and are independent of each other; the liquid resistance flow channel is arranged in the first structural layer, and two ends of the liquid resistance flow channel are respectively communicated with the single-hole liquid storage cavity and the buffer flow channel; the second structural layer is arranged on the top of the first structural layer and covers the top of the buffer flow channel.

Abstract: The invention provides a method for selecting a color for a chemistry or instrument based upon a parameter of a test, the method including: identifying a color corresponding to a parameter of a test for the parameter; selecting, if the color corresponding to the parameter has not previously been used for another parameter, the color for designating a chemistry or an instrument as corresponding to the parameter; selecting, if the color corresponding to the parameter has previously been used for another parameter, a different color other than the color for designating a chemistry or an instrument as corresponding to the parameter, wherein the selecting a color other than the color comprises identifying a color having a measure of change in visual perception of the different color against other previously selected colors a predetermined value from the other previously selected colors; and utilizing the selected colors for parameters across both chemistries (102, 104, 105) and instruments (101, 103) that are util

Abstract: The invention relates to a breath sensing devices for a portable apparatus, in particular a portable telecommunication device or a wearable device, the sensing device comprising an acoustic wave sensing means, like a microphone; and a gas sensing means, The invention furthermore relates to an electronic device comprising such a sensing device. In addition, methods are provided that allow calibrating a gas volume based on an output signal of an acoustic wave sensing means.

Abstract: An image processing device includes: a processor; and a memory encoded with instructions executed by the processor, including: imaging pluripotent stem cells with time in a culture process and acquiring a plurality of images, extracting a colony region of the cells from the image, extracting a high luminance region on the basis of a group of pixels with larger luminance values than a standard value from among pixels constituting the image, extracting an extraction target region with relatively high contrast in the colony region on the basis of the colony and high luminance regions, and outputting the extraction target region as an extraction result, wherein as a relationship among the colony, high luminance, and extraction target regions, the colony region is formed, the high luminance region is then formed therein, and the extraction target region is then formed in the high luminance region in the culture process of the cells.

Abstract: A quartz crystal microbalance coated with functionalized nanoparticles used to detect molecule-nanoparticle interactions to assist with characterization of difficult to predict molecule-nanoparticle interactions for novel ligand chemistries and, particularly, mixed ligand nanoparticles exhibiting different ligand morphologies, in order to quantify nanoparticle-molecule interactions independently from more complex solvation requirements.

Abstract: The present invention provides a detection reagent and therapeutic target for B cell tumor after targeted therapy and related applications. The reagent composition comprises 3 groups of antibodies, with the first group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD24 an antibody, an anti-CD20 antibody, an anti-CD81 antibody, an anti-CD45 antibody; the second group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD20 antibody, an anti-CD72 antibody, an anti-CD45 antibody; and the third group of antibodies including an anti-cytoplasmic CD79a antibody. The reagent composition of the present invention can be applied for the detection of B-lymphocyte tumors after targeted therapy by flow cytometry.

Abstract: This invention comprises compositions and methods to determine the prognosis of necrotizing enterocolitis.

Abstract: The present invention relates to an epitope of a thioredoxin-1 (Trx1) antigen and a use thereof, and more particularly, to the epitope, and an antibody or an antigen-binding fragment binding thereto. The epitope region of the human Trx1 antigen confirmed in the present invention may be effectively used in the development of an improved antibody to enhance the binding affinity of an anti-Trx1 antibody. In addition, the improved antibody of the present invention is effective in improvement of performance of a breast cancer diagnosis kit due to excellent binding affinity for Trx1 and very high sensitivity and specificity, compared to a conventional anti-Trx1 antibody. Further, the accuracy and reliability of breast cancer diagnosis may significantly increase because exceptionally high sensitivity and specificity are exhibited by detecting the monoclonal antibody of the present invention, which specifically binds to Trx1, rather than detecting CA15-3, another conventional breast cancer diagnostic biomarker.

Abstract: Provided is a universal method for quantitatively determining therapeutic tumor necrosis factor (TNF)-alpha inhibitors in patient samples that is sufficiently sensitive for being able to detect all therapeutic TNF-alpha inhibitors.

Abstract: The present disclosure relates to an antibody specifically binding to bovine pregnancy-associated glycoprotein 1 (bPAG1) or an antigen-binding fragment thereof. The present disclosure further relates to a hybridoma cell producing the antibody; a composition including the antibody as an effective ingredient for diagnosis of bovine pregnancy; and a kit for diagnosis of bovine pregnancy. The present disclosure also relates to a method of diagnosing bovine pregnancy. Binding specifically to bPAG1, which is a pregnancy-associated plasma protein in bovines, the antibody allows a simple diagnosis of pregnancy in animals such as bovines of which the reproduction is important, so that the antibody may be usefully applied in the livestock industry by increasing reproduction efficiency.

Abstract: Various aspects and embodiments of the present disclosure are directed to methods and compositions (e.g., kits) for the identification of subjects with misfolded proteins in their urine. For example, methods and compositions for determining that a urine sample from a pregnant woman contains or does not contain misfolded are provided. In some embodiments, the presence of misfolded proteins in a urine sample from a pregnant woman is an indication of preeclampsia.

Abstract: Methods for monitoring inflammation status of a subject comprise determining levels of at least one neutrophil activation marker, or at least three markers, in urine samples taken from the subject at multiple time points, wherein increased levels of the at least one neutrophil activation marker, or at least one of the markers, in a urine sample are indicative of or predictive of an exacerbation of inflammation and/or wherein decreased levels of the at least one neutrophil activation marker, or at least one of the markers, in a urine sample following an increase are indicative or predictive of recovery from, or successful treatment of, an exacerbation of inflammation. Corresponding systems, test kits and computer programs are provided.

Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.

Abstract: An automatic analysis device includes a processing unit 3 which performs the treatment on a specimen before analysis of the specimen, supply equipment which supplies a reagent to a reaction vessel 11 disposed in the processing unit 3, a liquid temperature adjusting unit 1 which adjusts a temperature of the reagent supplied to the reaction vessel 11 by the supply equipment, a control unit 201, and a first temperature detection unit 4 which detects at least one temperature of a temperature of the air within the processing unit 3 and a temperature of the reagent supplied to the reaction vessel 11, in which the liquid temperature adjusting unit 1 and the control unit 201 execute temperature adjustment of the reagent based on a first temperature detected by the first temperature detection unit 4.

Abstract: The automatic analyzer includes a housing unit capable of housing a plurality of reagent bottles each of which has an IC tag on one surface of short-side side surfaces thereof, an antenna used to communicate with the IC tag, a detector that detects the presence or absence of a reagent bottles, and a control unit. The housing unit includes a housing container cooled by a cooling machine, a heat insulating material, a reagent tray provided with a plurality of reagent bottle holding portions that hold the reagent bottles, a disk rotatably holding the reagent tray, and a driving unit driving the disk, and when it is unable to communicate with the IC tag of the reagent bottle installed in the reagent bottle holding portion where the reagent bottle is detected by the detector, the control unit determines that the reagent bottle is installed in a reverse direction.

Abstract: A management system including at least one processor, wherein the processor is configured to acquire an image obtained by imaging a sample container containing a sample, recognize relevant information related to reliability of a test result related to the sample based on the image, and derive reliability information indicating the reliability of the test result related to the sample based on the recognized relevant information.