Abstract: A system for measuring the neural activity of a living being, including an implantable measuring device equipped with a housing to be accommodated, at least partially, in a cavity formed in the cranium (C) of a living being, and including a system of electrodes for measuring the neural activity, arranged on one face of the housing, and electronic signal-processing device, which are accommodated in the housing and to which the electrode system is connected, a device for fixing the housing in the cavity, the fixing device including at least one device for mechanically holding the housing in the cavity, a device for fixing the mechanical holding device, which are arranged to fix the holding device in the cranium (C) on the periphery of the cavity, a device for adjusting the depth position of the housing in the cavity.

Abstract: A method for detecting a representative cardiac activity includes the arrangement of a plurality of electrodes, the measurement of the value of electrophysiological descriptors, and the calculation (CALC) of a score.

Abstract: Various embodiments of a system are disclosed. The system includes a sensing apparatus configured to monitor cardiac electrical activity of a patient and a computing apparatus operatively coupled to the sensing apparatus and configured to monitor cardiac electrical activity using the sensing apparatus to generate a cardiac signal over time, detect a pacing artifact in the cardiac signal, and determine to account for the pacing artifact when using the cardiac signal based on at least one pacing artifact characteristic of the pacing artifact in the cardiac signal. The computing apparatus is further configured to account for the pacing artifact when using the cardiac signal if it is determined to account for the pacing artifact.

Abstract: The present invention relates to a physiological measurement device (11) comprising a plurality of input channels (23), at least two of the input channels including a digital section configured to process a digital signal (d1, d2) representing an analog signal (e1, e2) present at an electrode (13) assigned to the respective channel, a signal combiner (31) configured to calculate at least one vector signal (x) from at least two processed digital signals (df1, df2). To achieve improved common-mode interference mitigation, it is proposed that the digital section of at least one input channel (23) comprise a digital filter (29) configured to filter the digital signal (d1, d2) based on a set of filter coefficients (G1, G2) and a processor (33) configured for calculating the set of filter coefficients (G1, G2) based on the vector signal (x1).

Abstract: An example medical system includes a plurality of electrodes configured to sense a cardiac electrogram of a patient; and processing circuitry configured to: perform feature extraction of the sensed cardiac electrogram to extract a plurality of features from the sensed cardiac electrogram; convert one or more of the plurality of extracted features to a respective feature image; apply a machine learning model, trained using cardiac electrogram data for a plurality of patients, to an image of the sensed cardiac electrogram and at least the respective feature image to determine whether one or more particular heartbeats in the sensed cardiac electrogram indicate a premature ventricular contraction (PVC) beat; and in response to the determination that the one or more particular heartbeats indicates a PVC beat, output a classification that the one or more particular heartbeats is a PVC beat.

Abstract: A method of analyzing a subject's cardiac condition, the method including measuring an ECG or an electrogram signal, extracting a high frequency (HF) portion from a QRS portion of the ECG or electrogram signal, producing a HFQRS signal, calculating a HF value based on analyzing the HFQRS signal, measuring at least one more physiological value associated with the subject, and analyzing the ECG or the electrogram signal based on the HF value and the physiological value. Related apparatus and methods are also described.

Abstract: A fieldable EEG signal monitoring device, system and method configured for receiving and analyzing EEG signals and other user and environmental signals that is easily operate and repaired by a user and that is able to correlate received user and environmental data from one or more user to enable users or third part users to make strategic decisions about health, work, police, and military actions.

Abstract: Electroencephalography (EEG) data may be analyzed to calculate various metrics such as maximum amplitude projection, node visit frequency, node transition frequency, and/or node transition polarity. The calculated metrics may be provided graphically in some examples. In some examples, the metrics may be provided graphically in combination with other data such as raw EEG traces.

Abstract: Some embodiments of the present disclosure are directed to methods, systems and probe devices for detecting EMG activity. In some embodiments, such methods, systems and devices are used in aiding the diagnosis of Obstruction Sleep Apnea (OSA). In some embodiments, a probe is provided and comprises an elongated member configured with a size and shape for placement adjacent at least one of the soft palate and pharyngeal wall of the patient after insertion of the probe into the patient. The probe may also include at least one sensor configured to sense at least EMG activity of muscle layers of at least one of the soft palate and pharyngeal wall and output sensor signals corresponding thereto. The signals may be monitored for EMG activity, and based on such activity, in some embodiments, a determination of whether the sensor signals of the detected EMG activity correspond to spontaneous EMG activity and/or abnormal motor unit potentials (MUPs).

Abstract: Disclosed is an apparatus for a motor imagery training, which includes a measuring unit that measures a brain signal while a user performs a motor imagery training, a preprocessing unit that performs preprocessing with respect to the brain signal, a feature extraction unit that selects a time period including information related to a motor imagery from the preprocessed brain signal and calculates feature data corresponding to the brain signal of the selected time period, and a classification unit that classifies the brain signal into one of a plurality of classes based on the feature data, and the motor imagery training is any one of a first training in which the user imagines moving a body part and a second training in which the user imagines feeling a somatosensory stimuli of a tangible object using the body part.

Abstract: A method of screening a patient for a degenerative neurological disorder. The method can comprise the steps of: providing a tablet computer having a touchscreen to the patient, instructing the patient to draw a plurality of shapes, wherein each shape of the plurality of shapes is of varying complexity, recording at least one drawing characteristic for each shape drawn by the patient, mathematically analyzing the at least one drawing characteristic to determine an objective rating for each shape, analyzing the objective rating for each shape using a random forest comprising a plurality of decision trees to determine an objective probability that the patient has a neurological deficit, wherein the objective probability that the patient has a neurological deficit is the percentage of the plurality of decision trees which indicate a disease state.

Abstract: A cognitive function estimation device 1X mainly includes a first state information acquisition means 15X, a second state information acquisition means 16X, and a cognitive function estimation means 17X. The first state information acquisition means 15X is configured to acquire first state information representing a first state of a subject regarding a cognitive function of the subject. The second state information acquisition means 16X is configured to acquire second state information representing a second state of the subject whose interval of state change is longer than the first state. The cognitive function estimation means 17X is configured to estimate the cognitive function of the subject based on the first state information and the second state information.

Abstract: A system and method for detecting seizures in a patient are disclosed. The method includes measuring at least one signal associated with the patient over a first time period, and calculating a first slope having a rate of change in a first signal of the at least one signal over the first time period. The first signal is a heart rate. The method also includes determining a difference between the first slope and a reference slope, as well as detecting an epileptic seizure based at least upon the difference between the first slope and the reference slope. Furthermore, the method includes quantifying the epileptic seizure by calculating a severity of the seizure. The severity is the product of a seizure duration and a seizure intensity.

Abstract: A patient support apparatus includes a controller, a sensor capable of detecting vital signs, and a point of care (PoC) device for assessing risk of developing sepsis and for providing local and/or remote indications to caregivers. The controller is coupled to the sensor and the point of care device, and the controller can analyze signals from the sensor and the point of care device to determine data indicative of sepsis.

Abstract: A system for diagnosing an esophageal disease includes at least one processor and at least one memory storing instructions. The instructions, when executed by the at least one processor, cause the system to: access, during a procedure involving an in-vivo device located within a person, data measured by the in-vivo device relating to an esophageal disease; evaluate, during the procedure while the in-vivo device is located within the person, a diagnosis for the esophageal disease for the person by applying a trained machine learning model to the data measured by the in-vivo device; and communicate, during the procedure while the in-vivo device is located within the person, the diagnosis for the esophageal disease.

Abstract: A method of assessing gut health in a subject is provided. The method involves placing a device on or near the subject's skin and measuring a level of hydrogen gas emanating through the subject's skin. The device includes an electrochemical sensor capable of detecting hydrogen gas and a means of connecting the device to an apparatus having a central processing unit (CPU). The apparatus provides information on hydrogen gas level and the hydrogen gas level is used to assess gut health of the subject.

Abstract: Systems and methods for assessing milk volume changes within a breast are described. Also described are systems and methods for assessing volume changes in the stomach of an infant.

Abstract: Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

Abstract: Provided is a pelvic inclination estimation device including a communication unit that acquires feature amount data including a feature amount to be used for estimation of a pelvic inclination, the feature amount being extracted from a gait waveform of a spatial acceleration and a spatial angular velocity included in sensor data related to movement of a foot of a subject, a storage unit that stores an estimation model that outputs an estimation value related to the pelvic inclination according to an input of the feature amount included in the feature amount data, an estimation unit that inputs a feature amount included in the acquired feature amount data to the estimation model and estimate a pelvic inclination of the subject according to the estimation value output from the estimation model, and an output unit that outputs information associated to the pelvic inclination of the subject.

Abstract: The present disclosure generally relates to systems and methods for determining and/or monitoring a sleep stage and/or a sleep quality metric for an individual using one or more sensors, and methods of treating medical conditions related thereto (e.g., obstructive sleep apnea).

Abstract: The present invention relates to devices, systems and methods for detecting disturbances that may occur during the sleep of a subject using measurements and assessments of mandibular rotation and movement of a sleeping subject. A sensing unit may be positioned onto the exterior of the subject's mandible and may generate data measurements corresponding to mandibular rotation and movement. For example, measurements by an accelerometer and gyroscope corresponding to rotation and movement of the mandible provide the necessary information to arrive at an accurate assessment of sleep stages, sleep indicators and/or other sleep related information which may be used to make recommendations regarding sleep conditions and/or disorders. A report may be generated including such sleep stages, sleep indicators and/or other sleep related information as well as any recommendations regarding sleep conditions and/or disorders for use for diagnosing sleep events such as obstructive sleep apnea (OSA).

Abstract: An autonomous drug delivery system advantageously utilizes physiological monitor outputs so as to automatically give a bolus of a rescue drug or other necessary medication when certain criteria and confidence levels are met. An emergency button is provided to manually trigger administration of the rescue drug. The rescue drug may be an opioid antagonist in response to an analgesia overdose, a hypotensive drug to avert an excessive drop in blood pressure or an anti-arrhythmia drug to suppress abnormal heartbeats, to name a few.

Abstract: A method for capturing patient feedback for a medical treatment includes: receiving user instructions indicating a symptom being treated, a symptom score for the symptom being treated, and an indication of a beginning of a treatment session; receiving patient feedback comprising an updated symptom score for the symptom being treated and/or absence or presence of one or more of a plurality of attributes; storing the received patient feedback and a time in the treatment session at which the respective patient feedback was received; repeating the receiving of patient feedback and storage of data during the treatment session; and receiving a user instruction indicating an ending of the treatment session, wherein an alerting module alerts a user of the computing device for input of patient feedback after a predetermined period of time has elapsed following receipt of patient feedback without a subsequent receipt of patient feedback.

Abstract: Systems and methods to determine if an individual is impaired. The system includes a display and a stimulus on the display. The system includes a controller programmed to move the stimulus about the display and one or more sensors that track eye movements and pupil size of a user due to movement of the stimulus or light conditions. The system includes a processor programmed to analyze the eye movements and pupil data size. The system is programmed to determine the drug, or category of drug, causing impairment. The method includes using and collecting data from a testing apparatus. The method includes processing the data with an automated impairment decision engine to determine whether a subject is impaired. The method includes using machine learning models or statistical analysis to determine whether a test subject is impaired. The automated impairment decision engine may be trained using machine learning and/or statistical analysis.

Abstract: The assisted bracket for postoperative joint activity exercise is provided, including an inner shell bracket, a primary swing arm bracket, a secondary swing arm bracket, an angle sensor, and a shell body. By setting up an assisted bracket for postoperative joint activity exercise, the primary swing arm bracket is positioned on the proximal limb of the patient, and the secondary swing arm bracket is positioned on the distal limb of the patient. The angle sensor is connected to the mobile APP in electrical signals through a communication module to facilitate patient movement, it can drive the primary and secondary swing arm brackets to move, allowing the angle sensor to record their motion data, thereby monitoring the exercise amount and exercise frequency of the patient. This allows patients to better engage in rehabilitation exercises and improve the effectiveness of postoperative rehabilitation exercises.

Abstract: A device is for measuring a body parameter for a subject. The device comprises a sensor for measuring the body parameter, a housing element for positioning the sensor on a body part of the subject and an actuator system within the housing element for applying a pressure to the body part. The actuator system comprises two states, a first state based on the actuator system applying a first pressure to a first area of the body part and a second state based on the actuator system applying a second pressure to a second area of the body part. The device also comprises a controller configured to apply the first and second states at different times.

Abstract: An example medical device includes a handle, an actuation mechanism coupled to the handle, and a delivery needle, wherein a proximal end of the delivery needle is coupled to a first end of the handle. A fluid delivery device is coupled to a second end of the housing, and a retractable sensor is positioned within the handle. The retractable sensor is configured to extend distally through a lumen of the delivery needle in a non-retracted position during placement of the delivery needle within a body of a patient, wherein actuation of the actuation mechanism causes the retractable sensor to retract proximally through the lumen of the delivery needle into the handle to a retracted position.

Abstract: Provided is an electrode catheter whose movable shape has a high reproducibility even when the load changes, and has a high degree of freedom in corresponding to the shape of a measurement site.

Abstract: An implantable sensor assembly for use during spinal fusion. The implantable sensor assembly can include a component of an implantable prosthesis and an implantable cartridge associated with the component. The implantable cartridge can include at least one sensor capable of detecting one or more kinematic measurements associated with a patient and generating sensor data, and an antenna in electrical communication with at least one sensor, wherein the antenna transmits sensor data to a receiver at a remote location.

Abstract: An exemplary method and system are disclosed for a fully implantable soft-membrane electronic system that can provide the continuous monitoring of real-time or semi real-time measurements of strain and/or other mechanical properties, via electrical measurements such as capacitance, over an inductive coupling between the measurement system and the implanted device.

Abstract: A sensing device may include a housing and one or more features configured to couple the housing against the outer surface of the bone of the patient. A sensing device may include onboard electronics carried by the housing, the onboard electronics comprising: communication circuitry, one or more sensors configured to generate data regarding one or more characteristics of the patient; and processing circuitry configured to activate the communication circuitry to send the generated data to a device outside the patient.

Abstract: Embodiments can relate to systems and methods for automatically detecting sensor compression in continuous glucose monitoring in real time. A system may include at least one sensor and at least one processor in communication with the at least one sensor. The at least one processor is programmed or configured to cause the processor to retrieve first measurement data including at least one time series of blood glucose (BG) measurements, the at least one time series being measured by the at least one sensor while not subject to compression; receive, from the at least one sensor, second measurement data including at least one BG measurement; determine a clearance value between BG measurements based on the first measurement data and the second measurement data; and generate a signal output indicating that the at least one sensor is subject to compression based on the clearance value between BG measurements exceeding a predefined threshold.

Abstract: A pulse manifestation determining method is provided. The pulse manifestation method includes following steps. A pulse signal for determination is obtained. A valid range of the pulse signal for determination is determined through identifying a reverse pulse. A pulse manifestation is determined based on the valid range.

Abstract: Systems, methods, devices, and machine readable media storing instructions (programming) for an instantaneous or nearly instantaneous (e.g., within 0.1 seconds, within 0.001 seconds, etc.), non-invasive, and easy-to-use transfer from a radial and/or brachial waveform to a carotid waveform or its reduced-order parameters are described. Some embodiments relate to systems, methods, devices, and programming for determining cardiovascular (clinical) indices and biomarkers from two or more of the radial and/or brachial and/or carotid waveforms (or their corresponding reduced-order representations).

Abstract: Disclosed is a method for processing human biological signal data, including: traversing an original human biological signal with a plurality of preset peak-to-peak value adjustment time windows; acquiring an original peak-to-peak value of the original human biological signal within a previous peak-to-peak value adjustment time window; determining a target adjustment multiple of the current peak-to-peak value adjustment time window based on the original peak-to-peak value and a preset target peak-to-peak value; and determining a plurality of actual adjustment multiples of the current peak-to-peak value adjustment time window based on the target adjustment multiple, and sequentially adjusting signal values of the original human biological signal at a plurality of sampling points within the current peak-to-peak value adjustment time window based on the plurality of actual adjustment multiples.

Abstract: Systems and methods for identifying someone intending to leave a bed or chair generally before or shortly after the bed or chair is exited. These can allow intervention where necessary to prevent some falls before they occur. The systems and methods typically collect and aggregate real-time patient data to detect “attempted bed exits”—attempts made by a patient which indicate that the patient may be attempting to leave the bed or chair and, determine their risk for falling. Where done in real time, a patient making an “attempt” to exit can be stopped before or shortly after an actual exit is made, permitting staff to assist with, or prevent, the exit as necessary.

Abstract: Systems, methods, apparatuses, and computer program products for non-invasive glucose monitoring. A method may include continuously capturing a photoplethysmography signal of a patient in real-time. The method may also include inputting a blood pressure measurement, demographic information, and the photoplethysmography signal into a mobile application. The method may further include transmitting, as input information, the blood pressure measurement, the demographic information, and the photoplethysmography signal to a cloud server. In addition, the method may include generating, based on the input information, a glucose prediction of the patient.

Abstract: A measurement device that includes a detection unit that detects a gait event from time-series data of sensor data related to motion of a foot, and a measurement unit that performs a measurement of lower limbs by using the sensor data for a prescribed period with a timing of the gait event as a start point, based on a geometric model on which a constraint condition related to motion of the lower limbs is imposed.

Abstract: A method for synchronizing recordings of two wearable devices (12,14) worn by a user (16) in a specific use case is designed to measure a characteristic behaviour of the user over a period of time. The method comprises acquiring first recordings via a first wearable device (12) operable via a first clock, and acquiring concurrent second recordings via a second wearable device (14) operable via a second clock, wherein each clock has a clock drift and offset. The first and second wearable devices are synced with a hub executable app (18) executed on a hub device (20). A clock-time correction (62) is implemented via the hub executable app before processing (64) the respective recordings for the specific use case. The clock-time correction ensures that respective recordings have been corrected in time so that a difference between clocks, or clock drift, of the two wearable devices is no more than a threshold duration of a shortest event specific to the characteristic behaviour being measured.

Abstract: A physiological information processing apparatus includes one or more processors, and one or more memories configured to store a computer readable instruction, when the computer readable instruction is executed by the processor, the physiological information processing apparatus is configured to: cause a plurality of physiological sensors to intermittently operate such that an operation time and a standby time are alternately repeated; obtain a plurality of pieces of physiological information on a patient from the plurality of physiological sensors during the operation time; and change an operation mode of the plurality of physiological sensors that intermittently operate in accordance with a condition related to at least a part of the plurality of pieces of physiological information or a condition related to at least a part of the plurality of physiological sensors.

Abstract: A digital kiosk for performing integrative analysis of health and disease condition and method thereof is disclosed. The digital kiosk (100) comprises a three-dimensional image capturing system configured for capturing phenotypic features associated with a patient using one or more computer vision-based models. The digital kiosk (100) further comprises one or more health sensors (102) configured for capturing physiological health signals associated with the patient, a user interface for obtaining one or more user inputs from the patient, a communication module for establishing communication session with one or more external devices (106), a hardware processor (208) and a memory (202) coupled to the hardware processor (208). The memory (202) comprises a set of program instructions in the form of plurality of subsystems (200) configured to be executed by the hardware processor (208).

Abstract: The present description relates generally to methods and systems for power management of a digital (e.g., electronic) stethoscope. In one example, an electronic stethoscope includes a chestpiece configured to be positioned on a patient, the chestpiece including a sensor, wherein the chestpiece further includes a computer processing unit (CPU) operatively coupled to a memory storing instructions that, when executed by the CPU, cause the CPU to automatically activate the electronic stethoscope in response to detecting a touch input via the sensor.

Abstract: A radiotherapy device may comprise a rotatable gantry and a bore tube defining a bore. The bore tube may comprise a first section formed of a first material and a second section formed of a second material. The first section may be configured to minimally attenuate an imaging beam, while the second section may be configured to meet further requirements of the bore tube.

Abstract: Imaging systems and methods estimate poses of a fluoroscopic imaging device, which may be used to reconstruct 3D volumetric data of a target area, based on a sequence of fluoroscopic images of a medical device or points, e.g., radiopaque markers, on the medical device captured by performing a fluoroscopic sweep. The systems and methods may identify and track the points along a length of the medical device appearing in the captured fluoroscopic images. The 3D coordinates of the points may be obtained, for example, from electromagnetic sensors or by performing a structure from motion method on the captured fluoroscopic images. In other aspects, a 3D shape of the catheter is determined, then the angle at which the 3D catheter projects onto the 2D catheter in each captured fluoroscopic image is found.

Abstract: A digital radiographic detector assembly having a housing with a radiopaque sheet and an electrical connector. A digital communication cable is attached to the electrical connector and is configured to be electrically connected to an image receptor positioned in the housing and to a radiographic imaging device. The radiographic imaging device detects that the digital radiographic detector is positioned in the housing and, in response, enables the start of a fluoroscopy exam.

Abstract: A radiology device includes an ionizing ray generator and a detector configured to detect the rays emitted by the generator, the generator and the detector being opposite with respect to one another, the device delimiting a useful volume, passed through by the ionizing rays from the generator and received by the detector, the generator comprising several sources distributed along a direction and each emitting a beam of ionizing rays that is essentially flat and of fantail form, the sources being disposed so as to irradiate all of the useful volume without translation. A method is provided implementing a device and consisting in successively sequencing the emission of several of the sources.

Abstract: Methods and systems are provided for increasing a quality of computed tomography (CT) images. In one embodiment, a CT system comprises an X-ray tube and an X-ray controller including one or more processors having executable instructions stored in a non-transitory memory of the CT system that, when executed, cause the one or more processors to, during a first view of a CT scan of an object, focus an electron beam at a first focal spot on a target of the X-ray tube, the first focal spot of a first size; during a second view of the CT scan, focus the electron beam at a second focal spot on the target, the second focal spot of a second size different from the first size; and reconstruct an image of the object from projection data including the first view and the second view.

Abstract: A radiation detection apparatus includes a first sensor panel that generates a signal in accordance with incident radiation, a second sensor panel that generates a signal in accordance with incident radiation, and an adhesive member that couples together the first sensor panel and the second sensor panel. When a stimulation is applied to the adhesive member, an adhesive force of the adhesive member is lowered to a strength at which the first sensor panel and the second sensor panel can be separated without causing damage.

Abstract: A portable medical imaging system and method, of which the system includes a movable station having a movable C-arm, an imaging signal transmitter attached to the movable C-arm, and an imaging sensor positioned generally opposite to the imaging signal transmitter and attached to the movable c-arm. The imaging sensor is configured to rotate relative to a point approximately on a center axis of the movable C-arm independently of the imaging signal transmitter, so as to change an angle of incidence for a signal transmitted from the imaging signal transmitter to the imaging sensor, and provide a field-of-view that is larger than the field-of-view of the imaging sensor at a single position.

Abstract: A C-arm x-ray imaging device includes a base, a carriage operably connected to the base and having at least one axis of movement with respect to the base; a C-arm movably connected to the carriage, the C-arm including an x-ray source and an x-ray detector disposed thereon in alignment with one another and a cable management system having a housing disposed on the carriage, the housing defining an interior, a number of cables extending from the base into the interior of the housing, a cable chain having a first end secured within the interior of the housing and a second end affixed to the C-arm, the cable chain defining a channel therein that receives the number of cables to direct the number of cables from the base to the C-arm. The cable management system operate to retain the number of cables in alignment with the C-arm in any orientation of the C-arm relative to the base.