Abstract: The bone measurement system is configured to detect a density of a metallic source within a bone. The bone measurement system includes an x-ray fluorescence (XRF) device, a filter, a radiation detector, a non-transitory computer-readable storage medium storing processor-executable instructions, and a processor. The XRF device may have an x-ray tube including an x-ray source and an anode. The x-ray source may be configured to produce an x-ray beam. The x-ray tube may include a backscatter geometry of around less than one-hundred and eighty degrees to more than ninety degrees. The filter may be disposed along a path of the x-ray beam. The radiation detector may be coupled to the XRF device.

Abstract: The present invention provides a train-like pharmaceutical composition (configuration, or dosage form) comprising segments linearly arranged in series like cars of a train. When the pharmaceutical composition is administrated into a patient's body, some of the segments are “visible” to an instrument, but others are not. However, “invisible” segments can be estimated, deduced, calculated, or inferred from “visible” segments. The “invisible” segments can be used for neutralizing intratumoral lactic acidosis combined with glucose deprivation to control tumor, among other applications.

Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.

Abstract: According to various examples, pharmacokinetics of a contrast medium through a cardiovascular system of a patient are estimated. This is achieved using analytical model(s) such as a compartment model or a linear time invariant model, and/or one or more neural network algorithms. An angiographic imaging protocol may be configured based on the estimate of the pharmacokinetics.

Abstract: Apparatus and methods are described including acquiring 3D image data of a skeletal portion. A computer processor (22) is used to designate a skin-level incision point (235) or a skeletal-portion level entry point within the body of the subject and associate the designated point with the 3D image data. A radiopaque element (258) is positioned on the body of the subject with respect to the skeletal portion and an intraoperative 2D radiographic image is acquired of the skeletal portion, such that the radiopaque element appears in the 2D radiographic image. The computer processor (i) registers the 2D radiographic image to the 3D image data such that the designated point appears in the 2D radiographic image, and (ii) displays a location of the designated point with respect to the radiopaque element on the 2D radiographic image. Other applications are also described.

Abstract: Described herein are systems, methods, and computer-readable medium for detecting a perfusion abnormality of a subject. In one embodiment, a method includes the following: obtaining, by dynamic radiography, imaging data for a dynamic series of a plurality of x-ray images that include areas of a subject corresponding to pulmonary vasculature; identifying, based on the imaging data, a dynamic signal corresponding to changing blood volume during the cardiac cycle of the subject; decomposing the dynamic signal into periodic components in frequency space; identifying, from the periodic components in frequency space, signals oscillating at the heart rate of the subject; generating, based on the identified signals oscillating at the heart rate of the subject, a perfusion map representation corresponding to pulmonary tissue perfusion in the subject; and detecting, based at least in part on the generated perfusion map representation, a perfusion abnormality of the subject.

Abstract: Various methods and systems are provided for agnostic transmission of radiation information data from a database to an analytics/business-intelligence tool. A system may include memory storing instructions executable by a processor to retrieve radiation dose data in a first format from a radiation dose database via an interoperability system operably coupled to the radiation dose database, convert the radiation dose data to a second format usable by a radiation dose consumer, and generate visualizations of the radiation dose data for display on a display device.

Abstract: An information processing apparatus determines, for each of a first radiation image corresponding to a first radiation energy and a second radiation image corresponding to a second radiation energy different from the first radiation energy, a first bone area indicating a predetermined bone portion, performs an alignment between a first partial area including the first bone area in the first radiation image and a second partial area including the first bone area in the second radiation image, and obtains a bone mineral density of the first bone area based on a difference image including the first bone area, the difference image is obtained based on a result of the alignment.

Abstract: The present disclosure relates to a method for removing an artifact in an image, an electronic device, and a storage medium. The method includes obtaining original scan data of a target object collected by a detector during a first imaging scanning, and performing an artifact correction on the original scan data with a scattering reference signal. The original scan data includes a scattering signal. The scattering reference signal is obtained based on energy data of the detector obtained under a condition that no slit is applied and energy data of the detector obtained under a condition that a slit is applied during a second imaging scanning.

Abstract: A radiographic imaging apparatus includes a plurality of pixels configured to convert radiation to electrical signals and a control section configured to determine an image capturing condition based on the electrical signals converted by the pixels and to start image capturing.

Abstract: Disclosed is an exposure dose management system including a first hardware processor that: manages exposure doses that a subject has received through imaging by a radiographic imaging apparatus in association with an imaging date and time; accepts a designation of a predetermined period; calculates a cumulative exposure dose obtained by accumulating exposure doses for which the imaging date and time corresponding to each exposure dose is included in the predetermined period from among the exposure doses managed by the first hardware processor; and outputs the cumulative exposure dose.

Abstract: A radiation imaging system includes a radiation imaging apparatus configured to transmit, based on electric charge generated in response to irradiation with radiation and a target value, a signal related to control of irradiation with radiation to an external apparatus; and a control apparatus configured to generate a target dose index value that is based on the target value and a dose index value that is based on information regarding electric charge, and determine whether the dose index value is within an allowable range of the target dose index value.

Abstract: A clamp for releasably engaging a cable chain employed on a C-arm X-ray imaging device includes a positioning member having a rear surface formed complementary to a portion of the C-arm imaging device, a pivot arm attached to the positioning member, a biasing member disposed on the pivot arm, and a clamp arm rotatably mounted to the pivot arm, wherein the biasing member is engaged between the positioning member and the clamp arm to move the clamp arm between a release position and a locking position. The clamp is engageable with the cable chain to hold the cable chain in alignment with the at least one of the housing and the C-arm, and is operable separately from the imaging device, such that the clamp can hold the cable chain on the housing or C-arm even when power is not provided to the imaging device.

Abstract: Systems and methods are disclosed to determine an indication of one of an atrial fibrillation S4 heart sound or a non-atrial fibrillation S4 heart sound for an S4 signal portion of cardiac acceleration information of a patient based on determined first and second correlations of a morphology of the S4 signal portion to atrial-fibrillation and non-atrial fibrillation S4 templates, respectively, and to determine an atrial fibrillation event of the patient using cardiac electrical information of the patient and the determined indication for the S4 signal portion.

Abstract: A device for detecting physiological sounds includes a thin film and a conductive element for conducting sounds to the thin film when contacting a skin of a live being. The conductive element is located on the thin film. The device of the invention can significantly improve the detection sensitivity and resolution of physiological sounds, and can give early diagnosis pathological sounds, for example, heart failure can be detected by means of heart sound diagnosis.

Abstract: An electronic stethoscope with a method of listening to sounds made by a heart, a lung, or blood flow along with using soundwaves transmitted from a transducer to observe a person's circulatory system wirelessly displayed onto a nearby monitor without switching devices.

Abstract: A vascular puncture device is a vascular puncture device that punctures a blood vessel using an imaging unit that comes into contact with a skin surface and acquires a cross-sectional image of a human body, a puncture unit including a sharp needle tip, and a drive unit moving the puncture unit, and includes a control unit that can receive information on the cross-sectional image and control an operation of the drive unit. The control unit identifies at least one blood vessel from the information on the cross-sectional image, determines whether the blood vessel is an artery or a vein from the information on the cross-sectional image of the identified blood vessel, sets a blood vessel to be punctured from among a plurality of the identified blood vessels, and controls the drive unit to move the puncture unit to puncture the blood vessel set to be punctured with the puncture unit.

Abstract: An intraluminal imaging device, includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The imaging device further includes an ultrasound scanner assembly configured to obtain ultrasound imaging data while positioned within the body lumen. The ultrasound scanner assembly is coupled to and positioned distally of the distal portion of the flexible elongate member. The distal portion of the flexible elongate member includes a first polymer with a first hardness. The imaging device further includes a reinforcement layer extending over and directly contacting only a region of the distal portion of the flexible elongate member. The reinforcement layer includes a second polymer with a different, second hardness.

Abstract: A system for determining a position or an orientation of a probe across a drape may include a fiducial assembly that may be coupled to the probe though a drape. The fiducial assembly may include a base, a coupling attached to the base which may be configured to couple the fiducial assembly to the probe across the drape, and one or more fiducials attached to the base. Coupling the fiducials to the probe across the drape can allow sterile fiducials to be coupled to a non-sterile probe to determine the position and orientation of the probe based on images from the of the fiducials on a sterile side of the drape. In some embodiments, the fiducial is aligned with respect to an elongate axis of the probe with a predetermined offset and orientation with respect to the elongate axis of the probe.

Abstract: Provided are an acoustic matching layer material containing a curing reaction product obtained by reacting an epoxy resin (A) having an epoxy equivalent weight of 140 or less with at least one of a curing agent (B-1) which is a monomer or a curing catalyst (B-2), and metal particles (C) having a density of 4.5 g/cm3 or more and less than 10 g/cm3 at 20° C., in which a content of particles (D) having a density of less than 4.5 g/cm3 at 20° C. is less than 5% by mass; an acoustic matching sheet; a composition for an acoustic matching layer material; an acoustic wave probe; an acoustic wave measurement apparatus; and a manufacturing method of an acoustic wave probe.

Abstract: A method for evaluating a contact state of an ultrasound probe on the basis of soft tissue morphology.

Abstract: A casing to store a portable imaging device, a method to be performed at the casing, and a machine-readable medium to cause one or more processors to implement the method. The imaging device is adapted to generate imaging data corresponding to a target being imaged using ultrasonic energy. The casing adapted to be opened and closed, and includes an exterior housing; an interior portion within the exterior housing to house the imaging device therein; a memory; a one or more processors coupled to the memory to perform computations on the imaging data from the imaging device to at least one of cause an image of the target to be displayed on a display or cause the imaging data to be stored in the memory; and a power source to supply charge to the imaging device.

Abstract: An ultrasonic wave generation device including: an ultrasonic wave generation source; an ultrasonic wave condensation part; and a waveguide. The ultrasonic wave condensation part has a first reflection surface opposed to the ultrasonic wave generation source and a second reflection surface opposed to the first reflection surface. The first reflection surface reflects the ultrasonic wave, generated from the ultrasonic wave generation source, toward the second reflection surface. The second reflection surface reflects the ultrasonic wave, which has been reflected by the first reflection surface, toward the waveguide so as to introduce the ultrasonic wave into the waveguide. The waveguide protrudes from the first reflection surface to a side opposite the second reflection surface. A recessed portion is formed from the first reflection surface to the second reflection surface side along an outer circumferential surface of the waveguide.

Abstract: One or more embodiments of the present disclosure may provide a power structure and an ultrasound probe. The power structure may include a driving assembly. The driving assembly may include a transmission device; the transmission device including a rotation component, a rope and an elastic component, and the rotation component including a driving wheel and/or a driven wheel. The driving wheel may be in a transmission connection to the driven wheel by the rope. The rope may be in an elastic connection to a body of the driving wheel and/or a body of the driven wheel through the elastic component. The rotation component may be provided with an accommodation cavity, and an extension channel in communication with the accommodation cavity. The elastic component may be accommodated in the accommodation cavity. One end of the rope elastically connected to the driving wheel and/or the driven wheel may be located in the accommodation cavity, and a portion of the rope may be located in the extension channel.

Abstract: The invention relates to an ultrasound system, in particular for cardiac monitoring, comprising a transducer array with a plurality of transducer array elements for providing ultrasound waves; a control unit, which is coupled to the transducer array, for controlling the transducer array, a data processing unit for receiving data from the transducer array and processing the received data, wherein the system further comprises at least one reference module configured for obtaining reference ultrasound data, at least one volume reconstruction module configured for reconstructing the volume of a target organ or part of a target organ, at least one selected monitoring unit configured for monitoring the volume of the target organ and/or part of the target organ. The invention further relates to a method for ultrasound imaging of a body part of a subject.

Abstract: A push wave transmission unit transmits a push wave to a biological tissue of a subject. A tracking wave transmission/reception unit transmits a tracking wave to the biological tissue and receives a reflected ultrasound wave reflected by the biological tissue. An elasticity analysis unit measures a propagation velocity of a shear wave generated in the biological tissue by the push wave and measures an elastic property of the biological tissue based on the propagation velocity, and measures the propagation velocity of the shear wave based on a measurement signal obtained by the reflected ultrasound wave received by the tracking wave transmission/reception unit. A controller determines whether to re-measure the elastic property according to an unnecessary component included in the measurement signal. When determining to re-measure the elastic property, the ultrasound diagnostic apparatus re-measures the elastic property by changing an acoustic property of the push wave according to the unnecessary component.

Abstract: An ultrasound imaging method includes: transmitting ultrasound waves to a target tissue at at least two different transmission angles; obtaining an ultrasound echo signal corresponding to each transmission angle; for the ultrasound echo signal corresponding to each transmission angle, performing beamforming at at least two different receiving angles to obtain beamformed data; based on each transmission angle and the receiving angles corresponding to the beamformed data, performing at least one coherent compounding and at least one non-coherent compounding on the beamformed data to obtain compounded data, where each coherent compounding includes performing coherent compounding on beamformed data corresponding to a same receiving angle and different transmission angles to obtain a set of coherently compounded data corresponding to the same receiving angle, and each non-coherent compounding includes performing non-coherent compounding on at least two sets of coherently compounded data; and generating an ultrasou

Abstract: A system and method is provided for analyzing image data acquired from a patient. The method includes receiving image data associated with a patient, determining image frames with predetermined anatomical information from the cardiac image data, providing the image frames with the predetermined anatomical information to a trained model, and determining at least one of dimensional, volume, area, or physiological measurements using the trained model.

Abstract: A method includes accessing ultrasound data encoding 3D surface information of one or more body structures in a region, extracting a first 3D surface representation of the one or more body structures based on the ultrasound data, accessing non-ultrasound imaging data obtained from performing non-ultrasound imaging of the region; extracting a second 3D surface representation of the one or more body structures based on the non-ultrasound imaging data; identifying, using a deep learning algorithm, one or more regions of interest (ROI)s from the first 3D surface representation such that when aligning the first 3D surface representation and the second 3D surface representation over the one or more regions of interest (ROI)s, a spatial transformation is determined; and based on applying the spatial transformation, generating an overlay of the 3D surface anatomical information from the non-ultrasound imaging data on the 3D surface information from the ultrasound data.

Abstract: Disclosed is an apparatus for collection and processing of a sample. The apparatus includes container that can contain a sample, and a capsule carrier assembly that supports a capsule portion. The apparatus further includes a fill nozzle mechanically coupled to the capsule carrier assembly and the container, wherein the fill nozzle provides a passageway for a portion of the sample to be transferred from the container into the capsule portion. A force exertion element exerts a force onto the sample in the container to move the portion of the sample into the capsule portion via the at least one nozzle. The portion of the sample passes through the filter prior to being moved into the capsule portion.

Abstract: An apparatus having a separation cell for separating drops of biological liquid from transport air in a flow coming from an endoscope is provided. The separation cell has an inner chamber having an upper inlet fluidically connectable to the endoscope, for receiving a flow containing drops of biological liquid mixed with transport air, a bottom outlet for exit of the drops of biological liquid, fluidically connectable to a suction pump and to an element for collecting and/or analyzing the drops of biological liquid, and an upper outlet for exit of the transport air and optionally of the drops of biological liquid and/or rinse water, fluidically connectable to a vacuum source. The separation cell forms a depression arranged between the upper inlet and the upper outlet. The depression extends downwards into the inner chamber and determines, for incoming transport air, a V-shaped path between the upper inlet and the upper outlet.

Abstract: A specimen holder includes a body, a cavity that extends into the body through an opening, and at least one slot. The specimen holder further includes a wireless transponder insertable into the cavity by increasing a dimension of the cavity, by increasing a dimension of the at least one slot. A wireless transponder loading cartridge includes a cavity that extends from an opening in the cartridge, and a plurality of wireless transponders positioned within the cavity. Each of the plurality of wireless transponders includes an outer peripheral shape that corresponds to a cross-sectional shape of the cavity. A wireless transponder dispenser includes a housing with a first recess that receives the cartridge and a second recess that receives the specimen holder. The wireless transponder dispenser provides a passage for wireless transponders from the cavity of the cartridge to a loading zone aligned with the cavity of the specimen holder.

Abstract: A biopsy device for percutaneous tissue removal includes an elongated housing having an operational axis, a stylet hub slidably mounted in the housing, where the stylet hub is movable relative to the housing between a proximal, armed position, and a distal, fired position, the stylet hub having a stylet strike, a cannula hub slidably mounted in the housing alongside the stylet hub, and a spring-biased arming member. The cannula hub is movable relative to the housing between a proximal, armed position, and a distal, fired position. The arming member is moveably mounted to the housing proximal of the respective stylet and cannula hubs, and configured for manually-actuated movement from a relaxed, extended position to a loaded, compressed position to define a compressive arming stroke. The biopsy device also includes an arming member biasing spring that restores the arming member from the compressed position to the extended position.

Abstract: Apparatus and methods for occluding hollow body structures, such as blood vessels, and for attaching tissue layers and/or non-tissue layers together by providing implantable elements on opposite sides of the structure or layers and drawing the implants together to occlude the body structure and/or bring the layers together. The implants are deliverable through a needle in a low-profile configuration and self-expand to an enlarged configuration. The implantable elements are delivered by transfixing the body structure, then releasing the implants on opposite sides of the body structure and drawing the implants together to effect an occlusion or attachment. The implants are configured to apply oppositely directed forces to opposite surfaces of the tissue layers at alternate, circumferentially spaced locations and may constrain the tissue in a serpentine pattern or in a direct clamping pattern.

Abstract: Vascular closure assembly device and method embodiments may be used to provide hemostasis at vascular puncture site or the like. Such vascular puncture or access sites may be created during a variety of percutaneous or minimally invasive medical procedures.

Abstract: A surgical retractor device has a housing with press arms coupled thereto, each arm having rotational movement in a plane, and a gripping member pivoting at right angle with the plane, at an outer end of the arm; an attachment means at an inner end of the arm; an opening and closing mechanism with rotatable press arm attachment structures attaching the attachment means of the press arms, symmetrically positioned from a centerline of the device; rotatable handle attachment structures, and; a transfer mechanism transferring rotation from handle attachment structures to press arm attachment structures. The device also has handles for operating the opening and closing mechanism. Each handle has a handle attachment means at an inner end of the handle for attachment to the handle attachment structures; and, a handle structure. The handles have a rotational movement in the plane and are symmetrically positioned from the centerline of the device.

Abstract: A surgical stabilizer arm includes a reusable base portion and a disposable arm portion. The articulating links that enable the arm to be positioned into arbitrary trajectories are included the disposable portion, thus eliminating the need to clean between the links after a surgical procedure. The disposable portion also includes a tool attachment mechanism and a cable. The reusable portion includes a retractor clamping mechanism, a top plate, a T-shaped base post, a main body, a nosepiece, a threaded drawbar, a thrust bearing assembly, and a threaded handle that can extend or retract the drawbar when rotated. The threaded drawbar may include a slot into which an end of the cable can be inserted, which allows tension to be applied to the cable when the handle is rotated to pull the drawbar into the body of the reusable portion and lock the articulating links in place.

Abstract: An ophthalmic speculum includes arms, a locking mechanism, and an air-flow system. The arms include a first arm and a second arm. Each arm has a retractor shaped to conform to an eyelid of a pair of eyelids of an eye. The retractors are substantially symmetrical about a lateral axis. The locking mechanism is coupled to the arms. The locking mechanism moves the arms to allow the retractors to retract the pair of eyelids, and fixes the arms into place to maintain retraction of the pair of eyelids. The air-flow system is coupled to at least one arm, and moves air in a region disposed outwardly from a surface of the eye.

Abstract: A system includes a first tube, a sharp coil at a distal end of the first tube, a second tube displaceable within the first tube, and a sharp housing at a distal of the second tube for storing fasteners. The housing can be positioned at a first tissue, and the coil rotated to advance the coil into engagement with the first tissue. The first tube is retracted to retract the first tissue, and then a first fastener is deployed at the first tissue location. Then, without removing the system from the patient, the distal end of the system is moved adjacent a second tissue location, and the process is repeated for a second fastener at the second tissue location. A suture extends between the first and second fasteners, and tension is applied to the suture to draw the first and second tissues toward each other to reconfigure the tissue.

Abstract: A fixation assembly for bone fixation and a method for joining bones or bone fragments of a single bone and translating uniform compression to the bones. The fixation assembly comprises a post member coupled to a screw member. The post member comprises a head portion connected to an anchoring portion, wherein the head portion is offset from the anchoring portion by a first angle. The head portion may comprise a curved body annularly extending from a first end to a second end, wherein the first end is separated from the second end by a slot, and wherein the curved body defines a tapered annular bore therein. The anchoring portion comprises a first leg extending from the first end of the curved body and a second leg extending from the second end of the curved body. The screw member comprises a tapered bulbous portion connected to a threaded elongated portion.

Abstract: A fixation device delivery system is described. The system includes a driver and a cooperating fixation element featuring a barb which becomes active upon deployment in the inner abdominal wall.

Abstract: A surgical instrument module for powering a plurality of discrete surgical end effectors includes a motor, a planetary gear box, a high-torque/low-speed output operably coupled to the motor, and a high-speed/low-torque output operably coupled to the motor. The high-torque/low-speed output is configured to be operably coupled to a driven member of a first type of surgical end effector, and the high-speed/low-torque output is configured to drive an operation of a second type of surgical end effector.

Abstract: A surgical stapling device includes an end effector having a cartridge assembly, and anvil assembly that is supported adjacent the anvil assembly in cantilevered fashion. The end effector of the stapling device includes a pusher that is configured to compensate for deflection of the anvil assembly and provide uniform staple formation along the length of the anvil assembly. The pusher is also configured to minimize firing forces required to fire staples from the cartridge assembly and cut tissue.

Abstract: A surgical stapling device includes an end effector frame and a replaceable reload assembly. The reload assembly includes a reload frame, a cartridge assembly, and an anvil assembly. The reload frame includes a longitudinal portion and a transverse portion that supports the anvil assembly. The longitudinal portion of the reload frame is engaged with the cartridge assembly via interlocking structure that facilitates movement of the cartridge assembly in relation to the anvil assembly between spaced and clamped positions. The reload frame is configured to be received on the end effector frame to properly position the cartridge and anvil assemblies in relation to each other.

Abstract: The present disclosure provides a staple cartridge for a surgical instrument having a staple and a staple pusher. The staple pusher has a recess forming a pocket in its top surface for receiving at least the backspan of the staple. The pocket is at least partially surrounded by a circumferential supporting element in the staple pusher body to support the backspan. The pocket provides additional vertical space and support for the staple such that a smaller staple cartridge may provide a substantially similar performance as conventional staple cartridges, allowing for a more compact and maneuverable surgical instrument. In addition, the pocket in the staple pusher allows for a staple having a larger bend radius than conventional staples, thereby providing additional support for the staple and minimizing malformation of the staple during use.

Abstract: Stapler cartridges and surgical apparatus that include a stapler cartridge can include a knife that retracts into the stapler cartridge after cutting stapled tissue to prevent an operator being cut by the knife during replacement of the used stapler cartridge with a new stapler cartridge. A stapler cartridge includes a staple pushing shuttle, a knife member slidably coupled with the staple pushing shuttle, and a cartridge body. The staple pushing shuttle is slidably coupled to the cartridge body. The cartridge body includes a guide track engaged by the knife member and configured so that a cutting blade of the knife member protrudes from the cartridge body during a first portion of a distal movement of the staple pushing shuttle and the cutting blade is retracted into the cartridge body during a second portion of the distal movement of the staple pushing shuttle.

Abstract: A system for compressing body tissue including a clip having first and second tissue compressing surfaces. The clip is movable from a closed position to an open position wherein the clip receives tissue between the first and second tissue compressing surfaces to compress tissue between the first and second tissue compressing surfaces. A clip deployment device has a first clip engagement member and a second clip engagement member engageable with the clip, the first and second clip engagement members movable between first and second positions to controllably move the clip.

Abstract: A vascular connector includes a tubular sleeve graft having a first layer and a second layer and a cylindrical connector body positioned within the tubular sleeve graft between the first layer and the second layer. The cylindrical connector body is more rigid than the tubular sleeve graft and is configured to slide longitudinally within the tubular sleeve graft between the first layer and the second layer.

Abstract: An anastomosis device for joining a first and second end of a vascular vessel is disclosed that includes a polymer cylinder ending in opposed first and second vascular-retaining ends configured for insertion into the first and second ends of the vascular vessel respectively. Each vascular-retaining end includes a plurality of bristles protruding outward. The device also includes at least one moiety covalently coupled to the surface of the device. The at least one moiety is selected from at least one anti-coagulant, at least one cell-specific binding peptide, and any combination thereof.

Abstract: Various types of otomy control devices that secure a periphery and/or adjacent tissue of a target otomy site and maintain the size of an otomy through a single wall of a vessel, organ, or lumen within the body. Among other things, this can reduce unintentional trauma, dilation, contraction, or locomotion of an otomy during a surgical procedure. They also can serve a beneficial purpose of allowing immediate communication between lumens before the complete creation of A permanent anastomosis. In some embodiments, magnetic compression anastomosis devices and/or other devices can be deployed through a channel of the otomy control device such as for deployment in a distal lumen.