Patents Issued in May 14, 2024
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Patent number: 11980735Abstract: Aspects of the disclosure are directed to methods and/or apparatuses involving modifying flow and/or concentration of an agent being injected for characterizing a vascular system. As may be implemented in accordance with one or more embodiments, a liquid including an agent is injected into a vascular system, by dynamically modulating a flow rate of the agent being injected over a range of flow rates. The vascular system is characterized based on a response of the vascular system to the dynamic modulation. In some implementations, such an approach involves using an injector that operates to separately control the rate at which an agent and other liquid such as saline are injected. These approaches can be implemented with modulation schemes using one or more of a variety of functions.Type: GrantFiled: August 7, 2019Date of Patent: May 14, 2024Assignee: Wisconsin Alumni Research FoundationInventors: Erick Louis Oberstar, Michael Antonio Speidel
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Patent number: 11980736Abstract: Methods and systems for infusing a user. An infusion pump includes a housing with an elastic component configured to expand and store potential energy. The infusion pump includes a first tube fluidically coupled to an outlet of the housing. The first tube is configured to conduct the fluid from the housing at a first flow rate. The infusion pump includes an air filter fluidically coupled to a distal end of the first tube via an air filter inlet. The infusion pump includes a second tube fluidically coupled to the air filter via an air filter outlet. The second tube is configured to adjust the first flow rate of the fluid conducted from the housing to a second flow rate. The infusion pump further includes one or more components for distributing the fluid to a user, the one or more components fluidically coupled to an outlet of the second tube.Type: GrantFiled: May 14, 2021Date of Patent: May 14, 2024Assignee: CareFusion 202, Inc.Inventor: Brett Franks
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Patent number: 11980737Abstract: A modular, semi-disposable patch pump for conducting a medical therapy includes a pump unit releasably connected to a reservoir unit by means of a bayonet connection; and a housing design for supporting both reliability and ease of use of said connection.Type: GrantFiled: June 21, 2021Date of Patent: May 14, 2024Assignee: TecMed AGInventors: Ursina Streit, Roland Margot, Jan Baumert, Simon Bosshard, Michael Hanimann, Patrick Hostettler
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Patent number: 11980738Abstract: Devices, kits and methods described herein are be used at chronic injection site or in conjunction with an indwelling catheter or cannula. A book-like packaging, applicator and/or tensioning device with an opening and optional indicia to align the catheter or cannula to the opening may be used to apply a dressing to a subject. The packaging, applicator and/or tensioning device may apply and/or maintain a strain in an elastic dressing.Type: GrantFiled: December 12, 2023Date of Patent: May 14, 2024Assignee: Neodyne Biosciences, Inc.Inventors: Kelley J. Lipman, Jasper Jackson, John A. Zepeda, Philip J. Wadlow, Reuben E. Lasrado
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Patent number: 11980739Abstract: A fluid delivery device has a syringe barrel-type reservoir with plunger, and plunger driver assembly comprising double-acting, telescoping lead screws that is located behind and outside of the barrel. Simultaneously and counter-rotating sleeve screw and center screw telescope out of a nested configuration of the plunger driver assembly and into the reservoir at a rate of double their individual and equal pitch and lead parameters when the sleeve screw is rotated. A threaded nut and gear anchor disposed on an end of the barrel receive the sleeve screw and the threaded nut causes the sleeve screw to translate and rotate in response to motor operation. A distal end of the center screw can be keyed to a plunger pusher for anti-rotation constraint when the motor is imparting rotation on the threaded nut and sleeve screw.Type: GrantFiled: August 13, 2021Date of Patent: May 14, 2024Assignee: Becton, Dickinson and CompanyInventors: Alessandro Pizzochero, Mark Wood, Muzaffer Yalgin Ozsecen, Timothy Blum, Eric Hassenpflug, Cory Baker, Jeffrey Held
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Patent number: 11980740Abstract: An insertion device to assist in accessing an access port that has been subcutaneously implanted in the body of a patient is disclosed. The implanted access port is accessed by a needle of a needle assembly, such as a needle-based infusion set. The insertion device may include a body having a stabilizing portion and a guide portion. The stabilizing portion stabilizes a position of the implanted access port when the body is placed on the skin of the patient atop the implanted access port. The guide portion is designed to guide a needle of the needle assembly along a predetermined path such that the needle transcutaneously pierces a septum of the implanted access port.Type: GrantFiled: September 13, 2021Date of Patent: May 14, 2024Assignee: C. R. Bard, Inc.Inventors: Glade H. Howell, Bradley J. VanderStek, Jeremy B. Cox, Laurie M. Whetstone, Manikantan Shanmugham, Jason R. Stats, Kenneth W. Sykes
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Patent number: 11980741Abstract: An optical circuit detects PPG signals reflected from skin tissue at one or more different wavelengths. A processing circuit integrated in the biosensor or in communication with the biosensor processes the PPG signals to obtain a period of vasodilation, a level of vasodilation and rate of change of the level of vasodilation. The processing circuit compares the level of vasodilation to a normal range and determines an arterial stiffness index using the comparison and the rate of change of the level of vasodilation.Type: GrantFiled: August 14, 2020Date of Patent: May 14, 2024Assignee: TRILINEAR BIOVENTURES, LLCInventors: Robert Steven Newberry, Matthew Rodencal
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Patent number: 11980742Abstract: A device for administering a fluid medicament by injection comprises a dosing portion (1) with a collapsible reservoir (10). The reservoir (10) has a maximum volume in an extended state and a minimum volume in a collapsed state. Prior to injection, the reservoir (10) is in the extended state and contains a liquid to be administered, and the reservoir (10) is biased towards the collapsed state. The device further comprises a needle (2), wherein a lumen (20) of the needle (2) is in fluid communication with the reservoir (10). The device further comprises a shield portion (3) with a plug (30). Prior to injection, the shield portion (3) is in a deployed position where the plug (30) blocks the lumen (20) of the needle (2). The shield portion (3) is adapted to move in response to an actuation force from the deployed position to a retracted position where the lumen (20) of the needle (2) is open, thereby causing the reservoir (10) to shift to the collapsed state to expel the liquid through the needle.Type: GrantFiled: December 22, 2015Date of Patent: May 14, 2024Assignee: Novo Nordisk A/SInventors: Carsten Schau Andersen, Simon Roervig, Steffen Hansen
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Patent number: 11980743Abstract: An apparatus for use in injectate delivery includes an actuator including a linkage, a force generating mechanism mechanically coupled to the linkage, and a controller coupled to the force generating mechanism. The force generating mechanism includes a passive force generator and an active force generator. In operation and on the basis of a control signal, the controller is configured to control the force generating mechanism to provide an input force to the linkage that is a combination of the first force provided by the passive force generator and a second force provided by the active force generator.Type: GrantFiled: August 10, 2020Date of Patent: May 14, 2024Assignee: Portal Instruments, Inc.Inventors: Andrew Coats, Robert J. Dyer
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Patent number: 11980744Abstract: Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.Type: GrantFiled: September 14, 2020Date of Patent: May 14, 2024Assignee: Sanofi-Aventis Deutschland GMBHInventors: Yannick Hourmand, Douglas Ivan Jennings, Matthew Ekman
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Patent number: 11980745Abstract: A low-waste needle and syringe assembly for injecting a fluid into a patient is provided. The syringe has hatch marks printed on the outer wall of the body to indicate the amount of fluid and/or the concentration of the fluid contained in a fluid chamber of the syringe. A syringe tip defining a substantially frusto-conical interior void extends from an end wall of the syringe. A needle hub holds a needle and is configured so that the hub can be selectively and securedly attached to the syringe. A frusto-conical member of the needle hub matingly engages the frusto-conical void of the syringe tip when the hub is secured to the syringe, forming a fluid-tight seal. A plunger positioned in the fluid chamber can be depressed by a user, and a piston cap attached to the plunger urges fluid in the chamber out of the chamber through the syringe tip and into the needle. The piston cap matingly engages the end wall of the syringe so that substantially all fluid is urged from the chamber to the needle.Type: GrantFiled: August 4, 2020Date of Patent: May 14, 2024Inventor: David B. Brothers
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Patent number: 11980746Abstract: A syringe is provided. The syringe includes a syringe barrel including an open proximal end, a closed distal end, and a sidewall extending therebetween. The syringe also includes: a plunger having an annular sidewall configured to seal against an interior surface of the sidewall of the syringe barrel, the plunger being configured to move through the syringe barrel in proximal and distal directions; a pump in fluid communication with an interior volume of the syringe barrel, the pump being configured to draw fluid from the syringe barrel; and a nozzle including a lumen in fluid communication with the pump and configured to receive fluid drawn from the syringe barrel by the pump and to expel the fluid through a distal end of the lumen. The pump can be a valve-less piston pump.Type: GrantFiled: April 12, 2019Date of Patent: May 14, 2024Assignee: Becton, Dickinson and CompanyInventor: Austin Jason McKinnon
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Patent number: 11980747Abstract: Implementations of the present disclosure are directed to an injection device (102) including a medicament reservoir (103) configured to store a medicament to be expelled by the injection device (102), an acoustic source (122a, 122b, 122c, 122d, 200, 300, 400) configured to generate an acoustic signal including information indicative of an amount of the medicament stored in the medicament reservoir (103), the acoustic signal being transmitted to an external device (104) configured to process the acoustic signal and to extract injection device data.Type: GrantFiled: February 21, 2023Date of Patent: May 14, 2024Assignee: SanofiInventors: Matthias Felber, Nathanael Wettstein, August Enzler, Felix Kramer
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Patent number: 11980748Abstract: A cartridge and loading system for loading tamper-evident syringe caps into a robotic pharmaceutical compounding device. The compounding device has a syringe finishing station, and can transfer tamper-evident caps from the cartridge to the syringe finishing station. The cartridge has a floor disposed at an angle to horizontal. The device may include a vibratory element for vibrating the cartridge, so that tamper-evident caps are fed to an outlet of the cartridge by gravity.Type: GrantFiled: August 28, 2020Date of Patent: May 14, 2024Assignee: Omnicell, Inc.Inventors: Ryan Kaintz, Peter Hoffman
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Patent number: 11980749Abstract: An autoinjector basically includes a housing, a pre-filled syringe, a drive chassis, and a needle guard. The pre-filled syringe is mounted in the housing. The drive chassis is configured to move a plunger in the pre-filled syringe to dispense medicament via an urging force from a drive spring. The needle guard is moveable in the housing between a storage state, a dispensing state, and a lock-out state. The needle guard is biased towards an extended position by a lock-out spring. The needle guard selectively engages the housing to establish a frontmost position of the needle guard in the storage state, and an offset position of the needle guard in the lock-out state. The offset position is axially offset from the frontmost position in the distal direction.Type: GrantFiled: October 31, 2022Date of Patent: May 14, 2024Assignee: MEDMIX SWITZERLAND AGInventors: William Geoffrey Arthur Marsh, Anthony Paul Morris, Matthew Meredith Jones, Aled Meredydd James
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Patent number: 11980750Abstract: An implantable device adapted for assisting the flow of blood from a left atrium to a descending aorta of an in-vivo heart is provided. The implantable device includes an inlet cannula adapted to be connected to the left atrium and an outlet cannula adapted to be connected to the descending aorta. In one embodiment, the inlet and outlet cannula is in fluid communication with a blood pressure pump. The implantable device further includes a first accelerometer mounted on a housing of the blood pressure pump, wherein the first accelerometer is adapted for measuring mitral valve motion. The implantable device also includes an implanted controller in electrical communication with at least one implanted ECG sensor adapted for detecting ECG signals, wherein the at least one implanted ECG sensor is positioned between the blood pressure pump and the implanted controller and the implanted controller also includes a processor adapted to analyse detected ECG signals and the mitral valve motion.Type: GrantFiled: May 2, 2019Date of Patent: May 14, 2024Assignee: NORTHERN RESEARCH ASInventors: Peter Ayre, John Begg, Tor Kristoffersen
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Patent number: 11980751Abstract: A first drive unit, in a state where a top end of a tubular joint is interposed into a chest of a target person and is located at a lower heart part, pushes a diaphragm out from the top end of the tubular joint while pressing a gas into the diaphragm, and simultaneously causes the diaphragm to start flexing to cover and wrap the lower heart part, and then stops pressing the gas into the diaphragm at a time point where compression balloons are positioned at atriums and ventricles of a heart, respectively; and second drive units support a pumping function of the heart by alternately repeating an ejecting operation to fill each of the compression balloons with a fluid and cause each compression balloon to expand and an absorbing operation to cause each compression balloon to discharge the fluid and contract.Type: GrantFiled: August 30, 2019Date of Patent: May 14, 2024Assignees: CYBERDYNE INC., UNIVERSITY OF TSUKUBAInventor: Yoshiyuki Sankai
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Patent number: 11980752Abstract: A surgical tool including first connecting elements, contacting elements, and conductive elements. The contacting elements are configured to contact nerve tissue of a patient. The conductive elements extend from the connecting elements to the contacting elements. The conductive elements have respective insulative outer layers. The insulative outer layers isolate the conductive elements from each other. The first connecting elements are configured to connect to and receive monophasic stimulation pulses from second connecting elements on a modular stimulation module. The modular stimulation module is configured to connect to the tool and other tools via the second connecting elements. The conductive elements are configured to transfer the monophasic stimulation pulses from the connecting elements to the contacting elements.Type: GrantFiled: April 26, 2021Date of Patent: May 14, 2024Assignee: Medtronic Xomed, Inc.Inventors: Kevin L. McFarlin, Bryan L. Courtney, Matthew L. Cantwell
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Patent number: 11980753Abstract: The present invention provides a catheter for assisting recovery from dysphagia.Type: GrantFiled: November 1, 2019Date of Patent: May 14, 2024Assignee: Phagenesis LimitedInventors: Conor Mulrooney, Veronika Matei-Rascu
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Patent number: 11980754Abstract: The disclosure relates to an electrode array that comprises a first region including a first group of electrodes of a plurality of electrodes and a second region including a second group of electrodes of the plurality of electrodes, where a silicone notch carrier is arranged between the electrodes of the second group, and where each of the silicone notch carrier includes a notch that is formed into the silicone notch carrier, and when the electrode array is straighten each notch has an opening angle and/or a bending radius which varies between the silicone notch carriers.Type: GrantFiled: October 22, 2021Date of Patent: May 14, 2024Assignee: Oticon Medical A/SInventor: Guillaume Tourrel
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Patent number: 11980755Abstract: An illustrative system includes a cochlear implant, a lead configured to be inserted into a cochlea of a patient by way of an insertion procedure, a plurality of electrodes disposed on the lead and including an intracochlear electrode and an extracochlear electrode, a probe coupled to the extracochlear electrode, and a processor communicatively coupled with the probe and the cochlear implant. During the insertion procedure, the processor directs the cochlear implant to short the intracochlear and extracochlear electrodes, then detects, by way of the probe and the shorted intracochlear and extracochlear electrodes, evoked responses measured at the intracochlear electrode. The evoked responses include a first evoked response measured at a first insertion depth and a second evoked response measured at a second insertion depth. The processor generates, based on the first and second evoked responses, a notification indicating that cochlear trauma has likely occurred at the second insertion depth.Type: GrantFiled: January 6, 2022Date of Patent: May 14, 2024Assignee: Advanced Bionics AGInventors: Kanthaiah Koka, Leonid M. Litvak
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Patent number: 11980756Abstract: The embodiments described herein relate to a self-positioning, quick-deployment low profile transvenous electrode system for sequentially pacing both the atrium and ventricle of the heart in the “dual chamber” mode, and methods for deploying the same.Type: GrantFiled: November 4, 2021Date of Patent: May 14, 2024Assignee: SWIFT SYNC, INC.Inventors: Christian Marin y Kall, Eduardo De Marchena
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Patent number: 11980757Abstract: The spinal cord stimulation device of this invention is configured for implantation into a patient so as to traverse the dura mater that surrounds the spinal cord. Placing the device in this location provides direct contact between the electrode and the cerebrospinal fluid (CSF), in close proximity to the spinal cord. The device has an intradural portion and an extradural portion that compresses and seals the dural membrane between them, securing the device in position and preventing leakage of CSF. The position of the device may be stabilized in relation to the spinal cord by way of a laminoplasty plate, bridging between the device and a vertebra. The device is electronically powered by an implanted pulse generator that produces a spectrum of signals to interrupt or otherwise attenuate transmission of pain mediating neural signals through the spinal cord.Type: GrantFiled: December 1, 2020Date of Patent: May 14, 2024Assignees: University of Iowa Research Foundation, University Of Virginia Patent Foundation, Direct Spinal Therapeutics Inc.Inventors: Matthew A. Howard, George T. Gillies, Logan Helland, Royce Woodroffe, Charles Romans, Saul Wilson, Daryl R. Kipke, David J. Anderson, Daniel J. O'Connell
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Patent number: 11980758Abstract: An implantable vagus nerve stimulation (VNS) system includes a sensor configured to measure ECG data for a patient, a stimulation subsystem configured to deliver VNS to the patient, and a control system configured to perform a heart rate variability analysis with the ECG data. In some aspects, performing the heart rate variability analysis includes measuring R-R intervals between successive R-waves for the ECG data measured during a stimulation period of VNS therapy and a baseline period of the VNS therapy, wherein the stimulation period comprises at least a portion of the ON period and the baseline period comprises at least a portion of the OFF period immediately preceding the ON period, and generating a plot of each R-R interval against an immediately successive R-R interval for each of the stimulation period and the baseline period configured to be displayed on a display.Type: GrantFiled: January 3, 2023Date of Patent: May 14, 2024Assignee: LivaNova USA, Inc.Inventors: Imad Libbus, Bruce D. Nearing, Badri Amurthur, Bruce H. KenKnight, Richard L. Verrier
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Patent number: 11980759Abstract: Systems and techniques for wireless implantable devices, for example implantable biomedical devices employed for biomodulation. Some embodiments include a biomodulation system including a non-implantable assembly including a source for wireless power transfer and a data communications system, an implantable assembly including a power management module configured to continuously generate one or more operating voltage for the implantable assembly using wireless power transfer from the non-implantable assembly, a control module operably connected to at least one communication channel and at least one stimulation output, the control module including a processor unit to process information sensed via the at least one communication channel and, upon determining a condition exists, to generate an output to trigger the generation of a stimulus.Type: GrantFiled: December 12, 2022Date of Patent: May 14, 2024Assignee: Purdue Research FoundationInventors: Pedro Irazoqui, Gabriel Omar Albors, Daniel Pederson, Christopher John Quinkert, Muhammad Abdullah Arafat, Jack Williams, Zhi Wang, John G. R. Jefferys, Thelma Anderson Lovick, Terry L. Powley, Rebecca Anne Bercich, Henry Mei, Jesse Paul Somann, Quan Yuan, Hansraj Singh Bhamra
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Patent number: 11980760Abstract: A pacemaker system includes a drive-sense circuit (DSC) operably coupled to a pacemaker lead. The DSC generates a pace signal including electrical impulses based on a reference signal. The DSC provides the pace signal via the pacemaker lead to an electrically responsive portion of a cardiac conductive system of a subject to facilitate cardiac operation of a cardiovascular system of the subject. The DSC senses, via the pacemaker lead, cardiac electrical activity of the cardiovascular system of the subject that is generated in response to the pace signal and electrically coupled into the pacemaker lead and generates a digital signal that is representative of the cardiac electrical activity of the cardiovascular system of the subject that is sensed via the pacemaker lead. The DSC provides digital information to one or more processing modules that includes and/or is coupled to memory and that provide the reference signal to the DSC.Type: GrantFiled: June 30, 2022Date of Patent: May 14, 2024Assignee: SIGMASENSE, LLC.Inventors: John Christopher Price, Shayne X. Short, Timothy W. Markison
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Patent number: 11980761Abstract: A pacemaker system includes a drive-sense circuit (DSC) operably coupled to a pacemaker lead. The DSC generates a pace signal including electrical impulses based on a reference signal. The DSC provides the pace signal via the pacemaker lead to an electrically responsive portion of a cardiac conductive system of a subject to facilitate cardiac operation of a cardiovascular system of the subject. The DSC senses, via the pacemaker lead, cardiac electrical activity of the cardiovascular system of the subject that is generated in response to the pace signal and electrically coupled into the pacemaker lead and generates a digital signal that is representative of the cardiac electrical activity of the cardiovascular system of the subject that is sensed via the pacemaker lead. The DSC provides digital information to one or more processing modules that includes and/or is coupled to memory and that provide the reference signal to the DSC.Type: GrantFiled: October 28, 2022Date of Patent: May 14, 2024Assignee: SIGMASENSE, LLC.Inventors: John Christopher Price, Shayne X. Short, Timothy W. Markison
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Patent number: 11980762Abstract: Brugada syndrome and related forms of ion channelopathies, including ventricular asynchrony of contraction, originate in the region near the His bundle or para-Hisian regions of the heart. Manifestations of Brugada syndrome can be corrected by delivering endocardial electrical stimulation coincident to the activation wave front propagated from the atrioventricular (AV) node early enough to compensate for the conduction problems that start in those regions. The stimulation can include waveforms of the same polarity delivered to a site within the region near the His bundle or para-Hisian regions of the heart associated with a low cardiac electrical asynchrony level or can include at least two single-phased superimposed waveforms of opposite polarity delivered through a pair of pacing electrodes relative to a reference electrode, which can be delivered to any site within the region near the His bundle or para-Hisian regions. Defibrillation can also be used to terminate an arrhythmia.Type: GrantFiled: July 25, 2022Date of Patent: May 14, 2024Assignee: NEWSTIM, INC.Inventors: Daniel Felipe Ortega, Luis Dante Barja
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Patent number: 11980763Abstract: A system for validating safety of a medical device in a presence of a magnetic resonance imaging (MRI) field is provided. The system includes a first electric field generating device configured to form first electric field and configured to receive a medical device at least partially within the first electric field, and a second electric field generating device configured to form a second electric field in proximity to the first electric field and configured to receive the medical device at least partially within the second electric field.Type: GrantFiled: December 1, 2021Date of Patent: May 14, 2024Assignee: Pacesetter, Inc.Inventors: Xi Lin Chen, Xiyao Xin, Shiloh Sison, Shi Feng
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System and methods of decreasing the directional sensitivity of axially aligned rechargeable implant
Patent number: 11980764Abstract: The instant application relates to inductive charging of devices subject to migration. Embodiments described herein provide charging to devices at variable depths and locations to accommodate both net displacement of an implantable device as well as angular rotation of the implantable device by selecting appropriate sets or subsets of available field generation coils.Type: GrantFiled: June 13, 2023Date of Patent: May 14, 2024Assignee: Medtronic, Inc.Inventors: Andrew Fried, Venkat Gaddam, Brett Otteson, Mehmet Arcan Erturk -
Patent number: 11980765Abstract: A neurostimulation system configured for providing neurostimulation therapy to a patient. A user customizes a pulse pattern on a pulse-by-pulse basis. Electrical stimulation energy is delivered to at least one electrode in accordance with the customized pulse pattern.Type: GrantFiled: May 6, 2021Date of Patent: May 14, 2024Assignee: Boston Scientific Neuromodulation CorporationInventor: Michael A. Moffitt
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Patent number: 11980766Abstract: A self-centering washer is positioned between the feedthrough and filter capacitor of a filtered feedthrough. The washer has openings through which first and second terminal pins extend. A first opening has an inner arcuate portion contacting the first terminal pin and an outer perimeter portion exposing the braze sealing the terminal pin to the insulator. A second opening has an inner arcuate portion contacting the second terminal pin and an outer perimeter portion exposing the braze sealing the terminal pin to the insulator. In an imaginary configuration with the first and second washer openings superimposed one on top of the other, the cumulative arcuate distance of the inner arcuate portions about one of the terminal pins, subtracting overlap, results in a gap between the superimposed washer openings that is less than a diameter of the first and second terminal pins so that the washer is prevented from lateral movement.Type: GrantFiled: October 6, 2023Date of Patent: May 14, 2024Assignee: Greatbatch Ltd.Inventors: Jason Woods, Robert A. Stevenson, Christine A. Frysz, Thomas Marzano, Keith W. Seitz
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Patent number: 11980767Abstract: A medical device management system comprising a defibrillating apparatus, which comprises a plurality of electrodes configured to monitor ECG signals and deliver a defibrillation shock. The system including a communication unit configured to establish a secured wireless network, automatically generate a first text message upon receipt of a signal indicative of deployment of the defibrillating apparatus, associate the first text message with a unit identifier, automatically send the first text message, automatically generate a second text message comprising defibrillation shock status upon delivery of the defibrillation shock, associate the second text message with the unit identifier, automatically send the second text message; and a handheld device associated with a caregiver and configured to receive the first and second text messages and associate the first and second text messages with the specific defibrillating apparatus based on the unit identifier specific to the defibrillating apparatus.Type: GrantFiled: December 4, 2018Date of Patent: May 14, 2024Assignee: ZOLL Medical CorporationInventors: Ziad F Elghazzawi, C. Shane Reid, Andrew D Funk, Robert H Gotschall, Charles E Sawyer, Jr., Melissa M Dascoli
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Patent number: 11980768Abstract: An example of subject may deliver a therapy by delivering energy to tissue. The system may comprise a magnetic field system and an electric field system. The magnetic field system may be configured to provide a magnetic field in a first direction to the tissue. The magnetic field system may include at least one magnetic field source to produce the magnetic field. The magnetic field produced by the at least one magnetic field source may include a magnetic field produced by at least one of a permanent magnet, a temporary magnet or electric current flow through a conductor. The electric field system may be configured to provide an electric field in a second direction to the tissue. The electric field system may include at least one electric field source to provide the electric field and the second direction is non-parallel to the first direction.Type: GrantFiled: July 7, 2021Date of Patent: May 14, 2024Assignee: University of Iowa Research FoundationInventors: Calvin S. Carter, Sunny C. Huang, Michael J. Miller, Charles C. Searby, Val C. Sheffield
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Patent number: 11980769Abstract: Heat and heat based treatments that may be used to modulate, inhibit and/or prevent one or more of the processes that contribute to certain vascular and/or arterial complications.Type: GrantFiled: March 28, 2018Date of Patent: May 14, 2024Inventors: Eamon McErlean, Gary Beale, Matthew Donald Kidd
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Patent number: 11980770Abstract: A phototherapy method includes: introducing an ultrasound endoscope into a digestive tract; visualizing an irradiation target site in a body by the ultrasound endoscope introduced into the digestive tract; puncturing a vicinity of the irradiation target site with a distal-end section of a needle tube that is made to protrude from a distal-end section of the ultrasound endoscope introduced into the digestive tract; exposing an optical fiber from the distal-end section of the needle tube that has punctured the vicinity of the irradiation target site, by making the needle tube retreat with respect to the optical fiber accommodated inside the needle tube; and radiating light emitted from the exposed optical fiber onto the irradiation target site.Type: GrantFiled: October 5, 2020Date of Patent: May 14, 2024Assignee: OLYMPUS CORPORATIONInventor: Tomohiko Mamiya
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Patent number: 11980771Abstract: A method of and apparatus for processing optical coherence tomography (OCT) scans through a subject's skin, the method comprising, using a computing device (1): receiving a plurality of OCT scans through the subject's skin (7), the OCT scans representing an OCT signal in slices through the subject's tissue; processing the OCT scans to determine a set of parameters; processing each parameter to determine a set of control settings for an energy-delivery device (20); transmitting the control settings from the computing device (1) to the energy-delivery device (20); in which the set of parameters comprises the depth of the superficial plexus (108) through the subject's skin (7).Type: GrantFiled: January 29, 2018Date of Patent: May 14, 2024Assignee: MICHELSON DIAGNOSTICS LTDInventor: Jonathan Denis Holmes
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Patent number: 11980772Abstract: This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2.Type: GrantFiled: January 31, 2022Date of Patent: May 14, 2024Assignee: PHOTOCURE ASAInventors: Kjetil Hestdal, Aslak Godal
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Patent number: 11980773Abstract: An illuminated bassinet including a light source for delivering therapeutic light and anti-bacterial light, where an interlock prevents the anti-bacterial light from being emitted while an infant is located in the bassinet. Also, a surgical illuminator configured to concurrently or alternately emit different wavelengths of light for treating a physiological condition and for affecting perception of the surgical opening.Type: GrantFiled: September 12, 2022Date of Patent: May 14, 2024Inventors: Peter Broer, Vedang Kothari, Alan Greszler, Joseph Dombrowski, David Felty, Michael Kerns
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Patent number: 11980774Abstract: Devices and related methods for impinging light on tissue to induce one or more biological effects, and more particularly illumination devices and related methods for phototherapeutic light treatments in the presence of vitamins are disclosed. Biological effects may include at least one of inactivating and inhibiting growth of one or more combinations of microorganisms and pathogens, including but not limited to viruses. Phototherapeutic light treatments in the presence of vitamins may involve providing one or more vitamins in the form of a coating or film on a surface of a target tissue and irradiating the target tissue with light. By performing the phototherapeutic light treatment in the presence of vitamins, efficacy of the light treatment may be improved, thereby reducing viral loads and/or reducing doses of light received by the target tissue.Type: GrantFiled: August 5, 2021Date of Patent: May 14, 2024Assignee: KNOW Bio, LLCInventors: Adam Cockrell, Nathan Stasko, Jacob Kocher
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Patent number: 11980775Abstract: Generally speaking, pursuant to these various embodiments a memory stores prescribed treatment instructions for a particular patient radiation therapy. Those treatment instructions specify clinical metrics for goals pertaining to at least one treatment volume for the particular patient. Either directly or inferentially those clinical metrics are prioritized. A control circuit automatically converts those treatment instructions into resultant radiation treatment plan optimization objectives where the automatic conversion can compatibly comprise a non-convex optimization objective. The control circuit then automatically iteratively optimizes the radiation treatment plan for the particular patient radiation therapy as a function, at least in part, of the aforementioned resultant optimization objectives to thereby produce an optimized radiation treatment plan for the particular patient that a radiation treatment platform then utilizes to administer therapeutic radiation to the particular patient.Type: GrantFiled: September 2, 2020Date of Patent: May 14, 2024Assignee: Varian Medical Systems International AGInventors: Emmi Ruokokoski, Jarkko Y. Peltola, Esa Kuusela
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Patent number: 11980776Abstract: Risks of radiation-induced toxicity associated with a radiotherapy treatment of a target region of a patient are predicted. Data associated with a region of interest comprising the target region is received. The received data includes a predefined dose map of the radiotherapy treatment and pre-radiotherapy-treatment imaging data of the region of interest. A trained machine-learning algorithm is applied to the received data. The trained machine-learning algorithm generates at least one toxicity indicator based on the received data. The at least one toxicity indicator is indicative of the risks of the radiation-induced toxicity.Type: GrantFiled: February 3, 2022Date of Patent: May 14, 2024Assignee: Siemens Healthineers AGInventors: Ali Kamen, Bin Lou, Fernando Vega
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Patent number: 11980777Abstract: Disclosed are methods of producing randomized ultrasound waves for providing sonodynamic therapy. The method includes coupling a sonodynamic therapy device with an array of piezoelectric transducer elements to a skin surface. A controller is configured to generate an electrical drive signal to produce ultrasound waves to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: GrantFiled: June 26, 2023Date of Patent: May 14, 2024Assignee: Alpheus Medical, Inc.Inventors: Vijay Agarwal, Braden Eliason, Jeremy Ling
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Patent number: 11980778Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.Type: GrantFiled: May 2, 2023Date of Patent: May 14, 2024Assignee: HistoSonics, Inc.Inventors: Jonathan M. Cannata, Ryan M. Miller, Alexander P. Duryea, Dejan Teofilovic, Zeljko Mladenovic, Aleksandra Rakic, Joshua Stopek
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Patent number: 11980779Abstract: The invention describes a cosmetic article, in particular for make-up, in stick form comprising a transparent external product and a liquid internal product in which solid decorative elements are dispersed. The cosmetic article features an attractive, original appearance, which can be appreciated from both an aesthetic and a functional point of view upon application thereof to skin.Type: GrantFiled: September 21, 2022Date of Patent: May 14, 2024Assignee: CHROMAVIS S.P.A.Inventors: Davide Costo Lucco, Stefano Luca Indaco
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Patent number: 11980780Abstract: The invention comprises a shampoo apparatus and method of use thereof, comprising: putting a shampoo and carbon dioxide into a container, at least a portion of the carbon dioxide comprising at least one of a solid form and a liquid form; sealing the container; warming the carbon dioxide by at least fifty degrees Fahrenheit to form a carbon dioxide gas, the carbon dioxide gas at least partially dissolved in the shampoo, the carbon dioxide gas comprising a concentration of one-half to ten percent of the shampoo by mass; and pressurizing the container to a pressure exceeding sixty pounds per square inch, such as where a headspace forms in the container, the headspace comprising the carbon dioxide at a concentration greater than one thousand parts per million, where the pressurized carbon dioxide yields a propulsive force, a foam expansion function, and a cleaning function.Type: GrantFiled: March 30, 2022Date of Patent: May 14, 2024Inventor: Nyangenya Maniga
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Patent number: 11980781Abstract: An article of outerwear which resists ignition and insulates against heat, the article of outerwear has a plurality of sections made from a fabric, such as woven fabric, knit fabric or a combination thereof. The plurality of sections allow the article of outerwear to stretch enhancing the comfort of the wearer of the article of outerwear. The outerwear may include a protective shroud/hood which has fans to circulate air inside the protective shroud/hood, the fans having air intake openings and vent openings, the air intake openings opening in planes which are perpendicular to planes in which the vent openings open.Type: GrantFiled: July 8, 2021Date of Patent: May 14, 2024Inventor: Kandis Moser
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Patent number: 11980782Abstract: A filter holder for a mask, includes: an air passage, with a backflow prevention means being located in a portion thereof; a filter receptacle surrounding the air passage, accommodating a filter therein, and comprising an air inlet and an air outlet on both ends thereof, respectively; and a passage-partitioning portion spaced apart from the filter receptacle and located to face the backflow prevention means with respect to the air passage, with a distal end thereof protruding into the air outlet to cause a direction in which air purified through the filter receptacle flows to be changed.Type: GrantFiled: November 15, 2018Date of Patent: May 14, 2024Assignee: YGF INC.Inventor: Young Gu Kim
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Patent number: 11980783Abstract: Fire protection systems and methods for ceiling-only high-piled storage protection. The systems and methods include a fluid distribution, detection and control sub-systems to identify one or more fluid distribution devices for controlled operation to address a fire.Type: GrantFiled: May 24, 2021Date of Patent: May 14, 2024Assignee: Tyco Fire Products LPInventors: Zachary L. Magnone, Daniel G. Farley, John Desrosier, Donald D. Brighenti, Richard P. Bonneau
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Patent number: 11980784Abstract: The invention includes an air mover device used for fire mitigation and protection. The core component is an air mover unit whose discharge airstream can be positioned using air rudders and/or a directional control assembly to provide air flows in optimum directions and capacity to counter unwanted fire progression or to promote fires in cases of back-burns. Additional support components include a power supply, its fuel source, a speed control mechanism for the air mover, an air mover inlet protective screen, a sparger unit to impart suppressant or retardant into the airstream, balancing feet, a removable nozzle, and instrumentation and controls to ensure function and safety of equipment and personnel. This device can be on a static or mobile platform, towed or self-propelled and can be locally or remotely controlled.Type: GrantFiled: August 19, 2021Date of Patent: May 14, 2024Inventor: Wayne Darnell