Abstract: A graft includes a biological graft. An embroidered textile supports the biological graft. Sutures attach the biological graft and the embroidered textile together.

Abstract: Absorbable implants can be used to create volume and shape in soft tissues with regenerated tissue. The implants comprise lattices formed from multiple unit cells. Unit cells can be coils or springs, skeletal polyhedrons, foams, or structures derived from mesh and fiber. The implants may be coated or filled with cells and tissues, and preferably with autologous fat graft. The implants are particularly suitable for use in plastic surgery procedures, for example, to regenerate or augment breast tissue following mastectomy or in mastopexy procedures, and can provide an alternative to the use of permanent breast implants in these procedures.

Abstract: A scleral lens for correction of keratoconus and/or presbyopia is disclosed herein. The scleral lens includes a lens body for providing vision correction for a patient, the lens body having a central virtual pinhole, and a peripheral portion of the lens body configured to rest against a sclera of an eye such that a cavity is defined between a posterior surface of the lens body and an anterior surface of a cornea of the eye. The lens body is formed from a substantially transparent material and the central virtual pinhole includes a darkened perimeter, and the darkened perimeter of the central virtual pinhole includes a darkened internal wall extending through the lens body.

Abstract: An ophthalmic device includes an optic including an optic axis and a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure including a closed loop extending from first and second attachment points to the frame. The closed loop includes a first hinge and a second hinge. The first hinge has a first section having a first component extending in a first angular direction, a second section having a second component extending in a second angular direction opposite to the first angular direction, and a first connecting section between the first section and the second section. The second hinge has a third section having a third component extending in the second angular direction, a fourth section having a fourth component extending in the first angular direction, the fourth section being connected to the second section to form the closed loop.

Abstract: A system and method of treating target tissue in a patient's eye, which includes generating a light beam, deflecting the light beam using a scanner to form first and second treatment patterns, delivering the first treatment pattern to the target tissue to form an incision that provides access to an eye chamber of the patient's eye, and delivering the second treatment pattern to the target tissue to form a relaxation incision along or near limbus tissue or along corneal tissue anterior to the limbus tissue of the patient's eye to reduce astigmatism thereof.

Abstract: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a method can comprise advancing a distal end portion of a delivery apparatus toward a native valve; visualizing under fluoroscopy and for a selected imaging view, a position of a radiopaque marker on the distal end portion relative to a guidewire extending through the delivery apparatus, the marker circumferentially offset from a selected commissure of the radially compressed prosthetic valve by a predetermined amount that is determined based on the selected imaging view; rotating the delivery apparatus until the marker is centered along the guidewire; and advancing the distal end portion into the native valve and inflating the balloon to radially expand and implant the prosthetic valve in the native valve such that the selected commissure is aligned with a commissure of the native valve.

Abstract: A prosthetic heart valve for the treatment of structural heart disease wherein the prosthetic heart valve includes an expandable frame that is formed of a rhenium containing metal alloy. The novel geometry of the expandable frame in combination with the frame being partially or fully formed of the rhenium containing alloy enables the formation of a frame that a) has an open cell geometry in the frame of the prosthetic heart valve that can be used to reduce delivery system size, b) has high radial strength, c) has improved restoration of the physiologic EOA, d) has lower recoil, e) has little or no longitudinal foreshortening, f) allows for proper placement of the bioprosthetic valve in relation to the native commissures of the valve, h) has symmetrical and cylindrical expansion of the prosthetic valve resulting in lower rates of leaflet thrombosis and structural valve deterioration, and i) prevents allergic response and restenosis associated with nickel content.

Abstract: For some applications, apparatus is provided for facilitating implantation of a prosthetic valve (150) at a native heart valve (120) of a subject, the apparatus comprising a prosthetic valve support (22), the prosthetic valve support (a) being configured to be transluminally-deliverable to the native valve and to be deployable at the native valve, and (b) comprising one or more tissue-engaging elements (24), configured to couple the prosthetic valve support to leaflets (128) of the native valve without eliminating check valve functionality of the native valve. Other embodiments are also described.

Abstract: A prosthetic heart valve for the treatment of structural heart disease wherein the prosthetic heart valve includes an expandable frame that is formed of a rhenium containing metal alloy. The novel geometry of the expandable frame in combination with the frame being partially or fully formed of the rhenium containing alloy enables the formation of a frame that a) has an open cell geometry in the frame of the prosthetic heart valve that can be used to reduce delivery system size, b) has high radial strength, c) has improved restoration of the physiologic EOA, d) has lower recoil, e) has little or no longitudinal foreshortening, f) allows for proper placement of the bioprosthetic valve in relation to the native commissures of the valve, h) has symmetrical and cylindrical expansion of the prosthetic valve resulting in lower rates of leaflet thrombosis and structural valve deterioration, and i) prevents allergic response and restenosis associated with nickel content.

Abstract: A prosthetic heart valve configured for transcatheter implantation is provided, the prosthetic heart valve including a prosthetic valve frame and a plurality of prosthetic leaflets and arranged to facilitate one-way inflow-to-outflow fluid flow in a proximal-to-distal direction when the prosthetic heart valve is in an expanded state. The prosthetic valve frame includes a plurality of struts, and is shaped so as to define a plurality of intermediate nodes that are intermediate proximal and distal ends of the prosthetic valve frame. A portion of the plurality of struts are intermediate struts. Each intermediate node has at least four struts extending therefrom, the at least four struts including (a) a distally-extending pair of two struts the at least four struts, and (b) a proximally-extending pair of two struts of the at least four struts. Other embodiments are also described.

Abstract: Prosthetic devices and frames for implantation at a cardiac valve annulus are provided that include an annular frame (having an inflow end and an outflow end) and a plurality of axial frame members that bridge two circumferentially extending rows of angled struts. The axial frame members can include a plurality of axially extending leaflet attachment members and a plurality of axial struts in a 1:1 ratio. Along each of the two rows, the frame can have at least three angled struts between adjacent axial frame members.

Abstract: Various examples address support structures (e.g., prosthetic valve support structures or frames) that incorporate a frame that, upon transitioning to a deployed configuration, include a proximal section has increased stiffness, or resistance to deformation in a transverse plane to a longitudinal axis of a device, including resistance to a change in shape, size, or both. Such an increase in transverse deformation resistance may be measured as an increase in radial compressive resistance or an increase in flat plate stiffness, for example, or both. Such increases in transverse deformation resistance may be realized through a reduction in length of the increased stiffness region of the support structure, such as through longitudinal compression of the region following an initial radial expansion of the region.

Abstract: A cassette is disclosed for use in a prosthetic suturing device. The cassette has a base. The base has a pair of pivots, a pair of alignment tabs, and at least one retention latch. The cassette also has a cover coupled to the base. The cover has at least one retention latch. The cover also defines one or more ferrule holders. The cassette further has one or more needles guided by the base and the cover. A surgical suturing device is also disclosed for use with a cassette. The suturing device has a cassette receiver and one or more needle drivers, each needle driver having a needle receiver positioned within the cassette receiver.

Abstract: A modular surgical apparatus is disclosed. Also disclosed is a modular incision apparatus. The modular incision apparatus may be used in a minimally invasive surgery. The modular incision apparatus includes a base having a pair of pivots, a pair of alignment tabs, a proximal opening, and at least one slide guide. The modular incision apparatus includes visual and cleaning access to the blade. The modular incision apparatus is suitable for safely, efficiently, and accurately making small incisions during surgical procedures. The modular incision apparatus provides a means of making small incisions of controlled depth, while reducing the chances of inadvertent exposure of surgical staff to sharp instrument.

Abstract: A device for inserting a guide wire suitable for heart valve prostheses into a blood vessel is provided. The device counteracts displacement of the threadlike elements if the distal portion, to which the threadlike elements are connected, is fixed to the internal catheter which has a handle portion that allows the surgeon to move this distal portion, and therefore also the threadlike elements, around the longitudinal axis of the catheter. The threadlike elements can be made by means of a first and a second plurality of notches offset from each other along the longitudinal axis, made on a median portion of the external catheter, in order to quickly and firmly position the threadlike elements against irregular walls of a blood vessel.

Abstract: The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve (i.e., mitral valve and/or tricuspid valve). For tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. There is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.

Abstract: A transcatheter heart valve prosthesis includes an annular stent, a valve structure including a plurality of leaflets positioned within and coupled to the stent, an inner skirt coupled to an interior surface of the stent, an exterior skirt coupled to an exterior surface of the stent, and a radiopaque marker is secured between the interior skirt and the exterior skirt.

Abstract: A method of replacing a native heart valve utilizing a support structure comprising a first fastener, a second faster, a first leaflet brace, and a second leaflet brace. The first leaflet brace is configured to be advanced over a first guide wire to be adjacent to a portion of a first native leaflet. The second leaflet brace is configured to be advanced over a second guide wire to be adjacent to a portion of a second native leaflet. The first fastener and the second fastener are configured to be advanced over the first and second guide wires to respectively engage with first and second ends of the first leaflet brace and the second leaflet brace. A replacement heart valve is deployed within the native heart valve, thereby capturing the first and second leaflets between the support structure and the replacement heart valve.

Abstract: Devices and methods for crimping a prosthetic heart valve onto a delivery device are described. In some embodiments, valves are crimped over an inflatable balloon and between proximal and distal shoulders mounted on a shaft inside the balloon. Crimping methods can include multiple compression steps with the valve located in different axial positions relative to the crimping jaws at each different step. In some methods, the valve may extend partially outside of the crimping jaws during certain crimping steps, such that the crimping force is only applied to the part of the valve that is inside the jaws. Exemplary crimping devices can include two or more adjacent sets of jaws that close down to different inner diameters, such that different parts of a valve get compressed to different outer diameters at the same time during a single crimping step.

Abstract: A device for inserting a guide wire suitable for heart valve prostheses into a blood vessel is provided. The device counteracts displacement of the threadlike elements if the distal portion, to which the threadlike elements are connected, is fixed to the internal catheter which has a handle portion that allows the surgeon to move distal portion and the threadlike elements around the longitudinal axis of the catheter. The threadlike elements can be made by means of a first and a second plurality of notches offset from each other along the longitudinal axis, made on a median portion of the external catheter in order to quickly and firmly position the threadlike elements against irregular walls of a blood vessel.

Abstract: The present invention relates to a prosthetic device for treating venous backflow, wherein the prosthetic device is configured for placement into the junction between right atrium and vena cava inferior of a patient. The prosthetic device comprises an expandable stent frame and a valve element attached to the stent frame as well as an annular positioning assembly coupled to the stent frame and extending outwardly and radially from the exterior area of the stent frame.

Abstract: The invention refers to an implant device (10) for treating an orbital floor fracture. The implant device (10) is foldable in a first direction between a folded state and an unfolded state and is plastically extendible in a second direction from an unextended state to an extended state. In the extended state, the implant device (10) has an extension in the second direction that is longer than a length in the unextended state and equal to or greater than an aperture distance of a human maxillary sinus in an anterior-posterior direction. The invention further refers to a related implantation tool, to a related implantation system for treating orbital blow fractures and to a corresponding implantation method.

Abstract: A modular glenoid component with an angled concave top surface for use with or as part of a modular shoulder prosthesis system that provides flexibility in shoulder replacements and ability to switch between a traditional anatomic Total Shoulder Replacement (ta-TSR) to a reverse Total Shoulder Replacement (r-TSR). The module glenoid component includes a base having the concave top surface angled from an anterior side to a posterior side such that the anterior side is higher than the posterior side. Optionally, the modular glenoid component includes a plug and/or a peripheral flange both of which when present extend in a direction away from a bottom surface of the base.

Abstract: A reverse shoulder system can include, for example, a glenoid baseplate comprising a longitudinal axis, the glenoid baseplate further including a stem and a central channel within a sidewall of the stem. The stem can include a longitudinal axis. The longitudinal axis of the glenoid baseplate can be angled with respect to the longitudinal axis of the stem, wherein the longitudinal axis of the glenoid baseplate is not perpendicular with respect to the longitudinal axis of the stem. Other components including a glenosphere, tools, and methods of use are also disclosed.

Abstract: Implants, devices, instruments, systems and methods for using the same for correcting bone deformities in the lower extremity are disclosed. Specifically, implants, devices, instruments and systems used for ankle fusion procedures are disclosed. The implants including an interior frame, an exterior frame surrounding the interior frame, and a lattice structure extending between at least a portion of the interior frame and the exterior frame.

Abstract: A bionic intervertebral disc with mechanical anisotropy includes an upper end plate, a core and a lower end plate. The core includes outer fibrous rings, a middle transition zone and an inner nucleus pulposus. The fibrous rings comprise collagen fiber sheets and collagen fibers, each of the collagen fibers is attached to a surface of a corresponding one of the collagen fiber sheets and arranged at an inclination angle, ones of the collagen fibers which are on every two adjacent layers of the collagen fiber sheets are arranged crosswise with each other. A honeycomb meshing size of a portion, which is located at a fibrous-ring transition zone, of the honeycomb structure is smaller and more compact, and a honeycomb meshing size of a portion, which is located at a nucleus pulposus transition zone, of the honeycomb structure is larger and sparser.

Abstract: A dynamically morphing intervertebral implantable device modularly configurable and resiliently adjustable under compressive loads generated between an upper and lower vertebra is disclosed. Specifically, the configurability of the structure enables to effect variable volume and area for safe insertion and secure implantation of the device with the attendant advantage for segment stabilization between the upper and lower vertebrae. Various geometric bodies including stowed or non-stowed structural elements integrated therewith are disclosed. The geometric bodies include a prismatic body, conical body, cylindrical body, and any combination thereof. The geometric bodies including the stowed or non-stowed structural elements are modularly configurable having various sizes and dimension to accommodate a range of intervertebral spaces in order to provide a tailored fit for individual patient anatomies.

Abstract: In some embodiments, the present disclosure relates to a system that includes an insertion tool and a drill guide. The insertion tool includes a body with a distal portion and a distal end. The body has a first engagement feature extending longitudinally along the distal portion and two arms extending longitudinally from the distal end of the body. The drill guide includes two bores and an open faced channel therebetween. The open faced channel includes a second engagement feature slidably engageable with the first engagement feature on the body of the insertion tool. The two bores are adapted for the disposal of a fastener driver tool therethrough.

Abstract: A system for delivering bone graft material into an interbody fusion device (IBFD) in an intradiscal space of a spine, the IBFD having an open-frame with a hollow interior and an opening through its proximal end communicating with the interior. Included is an elongate channel having a lumen extending therethrough, the distal end being in engagement with the IBFD to align the lumen with the opening through the proximal end of the IBFD. An adjustable block is movably attached to the channel, the block having plural chambers containing bone graft material, the chambers being individually sequentially alignable with the lumen. A plunger pushes graft material from each chamber, through the lumen and into the IBFD. A distal end of a tamper is configured to be inserted through each chamber and the lumen and into the IBFD interior for tamping graft material deposited into the interior of the IBFD.

Abstract: The disclosure provides example methods and non-transitory computer-readable mediums for acetabular cup placement. An example method includes a processor (a) determining for a first patient a sagittal acetabular cup position in the form of a standing AI, a seated AI and a SAA based on (i) a standing SS relative to a normative SS, (ii) a dSS between a standing position and an upright seated position, (iii) a femoral version corresponding to a femoral version outlier position, and (iv) a PFA to correspond to a PFA outlier position in a standing position or an upright seated position, (b) determining a coronal acetabular cup position in the form of a supine coronal anteversion and at least one of a supine or a standing coronal inclination based on the sagittal acetabular cup position, and (c) determining a post-operative standing AI and a post-operative seated AI based on the coronal acetabular cup position.

Abstract: Systems, methods, and devices are disclosed for surgical systems comprising an applicator having a first shaft, an implant having a first member pivotably and detachably coupled to the first shaft, and a second member for converting rotational motion of the implant to a translational offset, and at least one of a sensor for determining the offset or an indicator for indicating the offset, provided that the indicator is not a protrusion located at an end of the applicator. A controller may be provided, the controller being configured to receive offset data from the sensor, determine an angle of the implant in a patient using dimensions of the implant and the offset, and display a current position of the implant relative to patient anatomy. The applicator may have a second shaft slidably disposed on the first shaft along an axis defined by a longitudinal axis of the applicator.

Abstract: A mobility augmentation system monitors data representative of a user's motor intent and augments the user's mobility based on the monitored motor intent data. A machine-learned model is trained to identify an intended movement based on the monitored motor intent data. The machine-learned model may be trained based on generalized or specific motor intent data (e.g., user-specific motor intent data). A machine-learned model initially trained on generalized motor intent data may be re-trained on user-specific motor intent data such that the machine-learned model is optimized to the movements of the user. The system uses the machine-learned model to identify a difference between the user's monitored movement and target movement signals. Based on the identified difference, the system determines actuation signals to augment the user's movement. The actuation signals determined can be an adjustment to a currently applied actuation such that the system optimizes the actuation strategy during application.

Abstract: An endoprosthesis includes an elongated tubular member including a filament forming circumferential rows having a plurality of knitted loops and intermediate rungs extending between adjacent knitted loops. The tubular member includes at least one window and may include a plurality of anti-migration loops adjacent the at least one window and configured to shift between first and second positions when unconstrained. Making the endoprosthesis includes forming the plurality of knitted loops and intermediate rungs in a first row of loops and rungs, extending the filament to form a second row of loops and rungs interwoven with the first row, and forming the at least one window without cutting the filament. Placing the endoprosthesis includes positioning the endoprosthesis within a body lumen adjacent a branch lumen, expanding the tubular member to span the branch lumen, and shifting at least some anti-migration loops toward the second position and into the branch lumen.

Abstract: A system for implanting a flow modifying device in a heart comprises a flow modifying device comprising a tubular body comprising first and second openings located at first and second ends of the tubular body and a neck positioned between the first opening and the second opening, and a guide catheter comprising a flexible elongate shaft comprising a proximal portion comprising a fitting for receiving an insertion instrument and distal portion comprising an enlarged distal tip to prevent the flexible elongate shaft from passing through the flow modifying device. A guide catheter for cannulating a coronary sinus from a superior vena cava comprises a pre-formed distal portion comprising a proximal straight zone, a proximal curved zone extending along a first curved path, a distal straight zone extending along a straight path and a distal curved zone extending along a second curved path. The guide catheter can have different stiffnesses.

Abstract: A stent delivery device is provided that includes an inner member defining a distal tip and a stent holding region, and an outer tubular member slidingly disposed over the inner member and configured to engage the distal tip. Seal members may be disposed on one or more of an outer surface of the inner member, the distal tip, and the outer tubular member. The seal members define a liquid-tight sealed chamber surrounding the stent holding region.

Abstract: The present invention relates generally to an apparatus for placing a stent at a desired location within the human body. In particular, but not exclusively, the apparatus is configured to place a stent within the ureter or other passage or space within the human body. The invention may be embodied as an apparatus for inserting a stent into a bodily structure of a subject, the apparatus comprising: a stent guide wire, a first moving means configured to move the stent guide wire toward a bodily structure of a subject, a stent pusher disposed about the stent guide wire, and a second moving means configured to move the stent pusher independently of and relative to the stent guide wire.

Abstract: Embodiments of a balloon cover for a balloon catheter are disclosed. The balloon cover can include a first shell member and a second shell member. The first and second shell members are configured to matingly engage with each other to define a lumen that is configured to receive a distal portion of the balloon catheter. The first shell member includes a plurality of first wedges juxtaposed with a plurality of first cavities and the second shell member comprises a plurality of second wedges juxtaposed with a plurality of second cavities.

Abstract: Described herein are delivery devices and methods for deploying expandable implants into elongate tubular organs. The delivery devices may be configured to advance implants such as self-expanding springs within the tubular organ and release the springs at a target location where they expand and apply force to the wall of the tubular organ to lengthen the tubular organ. Delivery of the expandable implants for the treatment of small bowel syndrome is also described.

Abstract: A system is provided that stabilizes an applicator in response to the motion caused by a user. A motion stabilizer includes a receiver configured to be coupled with the adapter; at least one sensor configured to detect a movement caused by a user; circuitry configured to determine a compensation movement to offset the detected movement; and at least one motion generation device embedded in the receiver configured to control a motion of the cosmetic applicator according to the determined compensation movement. An application is configured to capture an image of the user prior to a session of applying a cosmetic using the cosmetic applicator; capture an image of the user after the session of applying a cosmetic using the cosmetic applicator; detect an error in applying the cosmetic to a portion of the user's body; detect a deviation in the movement of the cosmetic applicator during the session when the error is detected; and adjust settings for the motion stabilizer to compensate for the deviation.

Abstract: Systems and methods for effecting bariatric procedures are disclosed. Each system includes an instrument, a control valve and, optionally, a suction controller. The instrument is in the form of an elongated, flexible sizing tube having a distal end portion including plural apertures through which suction is applied for anchoring the sizing tube in the patient's stomach and for forming a visually perceptible delineation line on the exterior of the patient's stomach along which a portion of the stomach may be resected, sealed and tested. The elongated flexible sizing tube includes a source of illumination to produce near infrared light to facilitate the location of the sizing tube within the patient's stomach and to provide visual information about location of certain relevant internal anatomical features.

Abstract: An adjustable brace for stabilizing a body part of a patient and a method of fabricating such a brace is provided. In some embodiments, the adjustable brace comprises a first stabilizer having a first exterior surface, a first interior surface, a first thickness, and a plurality of first stabilizer guides; a second stabilizer comprising a second exterior surface, a second interior surface, a second thickness, and a plurality of second stabilizer guides; and at least one flexible lacing member extending along the first and second stabilizer guides, wherein the flexible lacing member adjustably secures the first stabilizer to the second stabilizer. Additional embodiments further include a closure mechanism to assist in the flexible lacing member adjustment.

Abstract: A joint support (1) for a joint region of a body part, in particular for a knee joint or elbow joint, having a sleeve-shaped base body (2) which can be stretched in multiple axes, characterized in that the joint support (1) has at least one tension strap (4) which runs over the joint and, in a flexed state of the body part, generates a tensile force (FZ) which promotes a return movement of the body part into a non-flexed position and/or in that the joint support (1) has at least one spring element in the form of a leaf spring (5) on the rear side of the joint, which spring element is tensioned in a flexed state of the body part and provides a restoring force (FR) which promotes a return movement of the body part into a non-flexed position.

Abstract: Examples are directed to an apparatus, device and/or method comprising promoting patency of an upper airway of a patient via mechanically maneuvering at least one of thyroid cartilage inferiorly, and hyoid bone anteriorly.

Abstract: Disclosed is a multi-directional jaw displacement oral appliance that is worn in the mouth of a user to reduce the effects of sleep apnea. The oral appliance includes an upper arch tray assembly against which the user's upper set of teeth are received and a lower arch tray assembly against which the user's lower set of teeth are received. An intermediate arch tray assembly is located between the upper and lower arch tray assemblies. The upper arch tray assembly is connected to the intermediate arch tray assembly by a hinge such that the upper arch tray assembly cannot be separated from the intermediate arch tray assembly and the upper arch tray assembly is rotatable through an angle with the user's upper set of teeth upwardly relative to the intermediate and lower arch tray assemblies.

Abstract: An oral appliance with an upper tray, a lower tray, and a flat cord that extends around and slides freely in a receiving slot formed on the front surface of the upper tray. The opposite ends of the flat cord extend diagonally rearward and connect to side connectors on the lower tray's outside surfaces of the two wing sections. The flat cord is made of non-elastic material, so it maintains its original length during use. During use, the flat cord self-adjusts its position over the upper tray to pull the wing sections on the lower tray forward relative to the upper tray evenly. A spacer may be formed on the abutting front curved surfaces of the front or lower trays to hold the trays' wing sections apart. The appliance may be distributed with a set of cords with different lengths that apply different pulling forces on the lower tray.

Abstract: An intraurethral contraceptive device includes an insertion tool and a urethral sleeve inside the insertion tool. The urethral sleeve includes a balloon on an outer surface and a distal proximal end of the urethral sleeve, having an air lumen that extends to a distal end of the urethral sleeve. There is an inside reservoir at a distal end of the sleeve, configured to capture any fluid traveling from the proximal end to the distal end of the urethral sleeve. An insertion plunger is coupled to a plunger head. The insertion plunger is configured to be placed inside a distal end of the insertion tool.

Abstract: The present disclosure relates generally to a modular brace system for either knee or back stabilization. The system includes either a knee brace or a back brace comprising a main body portion and side straps configured to wrap around a user's knee or back, as appropriate, and releasably secure to the brace to provide compression. The system also includes at least one of a gel pack and a heat pack to provide hot and/or cold therapy to the affected area. The gel and heat packs are releasably engageable with the brace so that they can be switched out as necessary.

Abstract: Continuous core body temperature measurements are made during hypothermic operations, where the core body temperature of the patient is lowered to reduce swelling. Caregivers monitor the patient's core body temperature to prevent damage that can occur to the patient if the patient's core body temperature becomes too low. To accurately determine the core body temperature of the patient, a temperature monitoring system measures the temperature at or near the surface of the patient and through at least a portion of a thermal block at multiple locations.

Abstract: A first sponge device for use to manipulate and prepare the surface of the epithelium of an eye prior to application of an ophthalmic solution has a handle and a sponge head secured to the handle. The head is made of an absorbent, wicking sponge material and has a non-sharp, tissue preparation surface of predetermined shape for rubbing across the surface of the epithelium layer in order to manipulate the tissue. After the surface is prepared, a second, holding sponge is placed over the eye to act as a reservoir and to hold ophthalmic solution against the eye surface.

Abstract: A dry eye treatment device includes a substrate. At least one reservoir is formed in the substrate. A histamine agonist is disposed within the at least one reservoir. The histamine agonist is configured to be delivered to at least one histamine receptor on or adjacent to an eye.