Abstract: An endoscopic visualization system including an endoscopic subsystem comprising: an endoscope having an optical channel and an illumination channel; an image sensor operatively coupled to receive light from the optical channel; and a solid-state light source operatively coupled to transmit light through the illumination channel; at least one electrical cable extending from the endoscopic subsystem; and a monitor subsystem comprising: a frame defining an inner compartment; a display screen; and at least one port configured to receive the at least one electrical cable connected to the endoscopic subsystem.

Abstract: An endoscope tip part including an exterior housing including a circumferentially extending side wall with a proximal opening, the circumferentially extending side wall defining an interior space with an air volume; a camera assembly positioned in the interior space so that the air volume envelops at least the distal portion of the camera assembly; and an interior housing part including a circumferentially extending closure surface and a circumferentially extending attachment surface, the interior housing part being positioned in the proximal opening; wherein the exterior housing and interior housing part are formed as separate prefabricated components, wherein the closure surface is configured for closing the proximal opening of the exterior housing so as to liquid-seal the air volume in the tip part, and wherein the attachment surface extends proximally from the proximal opening and is configured for attaching the interior housing part to another element of the tip part.

Abstract: A medical observation system includes a white light source that emits white light, an infrared light source that emits infrared light, a light source controller that performs control to alternately repeat a first mode and a second mode in chronological order, in the first mode the white light source is caused to emit the white light, and in the second mode the infrared light source is caused to emit the infrared light and the white light source is caused to emit light with a wavelength from green to blue wavelength bands, and an imaging unit that captures a subject. Therefore, a medical observation system is provided that is configured to simultaneously perform normal observation and infrared observation without hindering the operation of an operator.

Abstract: One embodiment of the present invention is a processor for an endoscope configured to process a captured image of a biological tissue. This processor for an endoscope includes: a light source device that emits a light for illuminating a biological tissue; a spectrum sensor that acquires an optical spectrum of an emitted light from the light source device; and an adjustment unit that adjusts the optical spectrum of the emitted light from the light source device so that a difference between the optical spectrum acquired by the spectrum sensor and a predetermined target spectrum is reduced.

Abstract: An intubation system is provided including an endoscope, a laryngoscope, and a display adaptor. The endoscope includes an endoscope video camera and at least one light emitting diode at a distal end, the endoscope video camera generating an endoscope video stream. The laryngoscope includes: a laryngoscope video camera for generating a laryngoscope video stream and a button. The display adapter is configured to receive the endoscope video stream and the laryngoscope video stream and to supply the video stream to a display. The button allows user selection of which of the laryngoscope video stream, and the endoscope video stream, or both video stream to supply from the display adaptor to the display.

Abstract: A reprocessing case may be used to assist in reprocessing an instrument, such as an endoscope in an automated reprocessor. The reprocessing case may include various features such that the case may include and be transitioned between a closed configuration, an open configuration, and a disinfection configuration. In particular the reprocessor may transition the case to a disinfection configuration during a reprocessing procedure.

Abstract: Provided herein are systems, methods, and apparatuses for diagnosing otitis media and related conditions using multiple sensing and imaging technologies.

Abstract: This application discloses systems and methods for automated vision testing. Performing automated vision testing can be beneficial in a number of eye care applications due to the reduction of chair time, increase of the measurement accuracy, elimination of human errors, capability for internal instrument calibration, and the possibility for test standardization.

Abstract: A handheld smart phone includes programming for performing various vision-related tests. The smart phone includes a touch sensitive screen, microphone, speaker, other sensors, processor and persistent storage for execution of software, multiple communications network interfaces and other device interfaces. The display delivers vision tests and, together with the speaker, related audio instructions to a user. The user interacts with the vision tests by using tactile and audio commands to the device screen and microphone. The test results are assembled into a report that can be transmitted to persons of the user's choice, such as a care provider. The capability is included for transmitting results to the remainder of the system for storage, analysis, events, alerts for medical personnel's user treatment and multiple user population analysis.

Abstract: The invention relates to a method for monitoring and/or evaluating the topographical positioning of a toric intraocular lens (14) during an operation on a human eye, by means of which the toric intraocular lens (14) is inserted into the human eye and is intended to be brought into its desired end position, the method comprising the following steps: determining at least one axis (7) of an astigmatism to be corrected of a cornea (1) of a human eye, in particular the axis (7) of the plane (2) of incidence of the strongest light refraction and/or the axis of the plane (3) of incidence of the weakest light refraction; and presenting the target axis (18) for the preferred axis (17) of the toric intraocular lens (14) relative to the determined axis (7) of the astigmatism in an electronic display device (19) of an apparatus (21), such that the movable toric intraocular lens (14) can be topographically situated and brought into its desired end position on the basis of the presentation.

Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. Measurement data may be processed using a decurving process to enhance the resolution of the ILM layer and provide improved determinations of retinal thickness.

Abstract: A method for estimating refraction of an eye of an individual, including: a) providing a set of N acquired eccentric photorefraction images of the eye, b) setting values for a set of parameters including at least sphere, c) providing a set of N simulated eccentric photorefraction images, d) determining an estimator of a difference between the set of N acquired eccentric photorefraction images and the set of N simulated eccentric photorefraction images, e) performing an optimization using an optimization algorithm so as to optimize the estimator by adjusting values for the set of parameters and iterating steps c) and d), and f) deducing an estimation of at least one refraction parameter of the eye.

Abstract: Clinical-quality eye examinations are provided at locations remote from the physician and outside of a clinical setting. A portable optical device and corresponding software are delivered to the patient's location. The portable optical device is configured for patient use in self-conducting an eye or vision exam and taking optical measurements. As a function of type of optical measurement data or health consideration of the patient, the corresponding software provides uploading and live streaming of the optical measurement data to the physician. The corresponding software is executed during the patient conducting the eye (vision) exam and enables the remotely located physician, to participate in the same via video conference. Alternatively, an artificial intelligence resource operating remotely or locally can provide physician-type guidance and eye health assessments. Alignment of device and patient eyes can be facilitated for remote exams.

Abstract: Methods, systems and apparatus including computer programs encoded on a “mobile device” for measuring intraocular pressure among other parameters of an eye using image processing with deep neural networks. One or more physical processors of the computer system are programmed with computer program instructions which, when executed cause the computer system to obtain an image of the eye to be used for intraocular pressure measurement. One or more physical processors of the computer system are programmed with computer program instructions which, when executed cause the computer system to estimate the intraocular pressure of an eye from a picture of that eye.

Abstract: A wireless electrocardiogram (ECG) system is provided. The wireless ECG system includes a plurality of wireless contact leads positioned on different areas of a body of a patient. Each of the wireless contact leads wirelessly send is a plurality of signals received from the body of the patient. An processing unit receives the signals from the wireless contact leads. The processing unit processes the signals into data indicative of electrical activity of the body. A charging component is coupled to the processing unit. The charging component includes a plurality of slots for charging each of the wireless contact leads.

Abstract: A security gateway for touch-free infectious disease screening includes a contactless sensor, a memory and a processor. The contactless sensor is configured to obtain health readings of a subject. The memory stores instructions. The processor executes the instructions. When executed by the processor, the instructions cause the security gateway to measure vital signs based on the health readings of the subject, and determine whether to allow access to a premise based on the vital signs.

Abstract: An implantable device for detecting biomarkers in animals, the device comprises: a sensor comprising: a pair of electrodes spaced apart from each other, the pair of electrodes having a first capacitance; an oscillator configured to oscillate at a first frequency and output a first signal at the first frequency; wherein the sensor is configured to receive an amount of biological fluid wherein the biological fluid causes the capacitance of the pair of electrodes to change from the first capacitance to a second capacitance; wherein the oscillator is coupled to the pair of electrodes and arranged such that a change in the capacitance of the pair of electrodes causes a change in oscillation of the oscillator from the first frequency to a second frequency; and wherein the oscillator is configured to output a second signal at the second frequency, the second signal indicative of a biomarker in the biological fluid.

Abstract: A method and system for creating a dynamic self-learning medical image network system, wherein the method includes receiving, from a first node initial user interaction data pertaining to one or more user interactions with the one or more initially obtained medical images; training a deep learning algorithm based at least in part on the initial user interaction data received from the node; and transmitting an instance of the trained deep learning algorithm to the first node and/or to one or more additional nodes, wherein at each respective node to which the instance of the trained deep learning algorithm is transmitted, the trained deep learning algorithm is applied to respective one or more subsequently obtained medical images in order to obtain a result.

Abstract: The invention relates to the technical field of characterising lesions in the liver using dynamic contrast-enhanced magnetic resonance tomography.

Abstract: Techniques are disclosed for measuring a concentration of an analyte in a subject based on reflectance spectra obtained from the subject. The spectra are obtained while and/or before and/or after photoreactions are induced in the subject, where the photoreactions change the reflectivity of the subject. The rate of change of the reflectivity is correlated with the concentration of the analyte.

Abstract: A method and a device of measuring a tissue element, and a wearable apparatus. The method includes: irradiating a measurement region with incident light having a single predetermined wavelength, where the incident light passes through the measurement region to form exit light exited from at least one exit position; obtaining a light intensity value corresponding to the exit light acquired by M photosensitive surfaces so as to obtain T output light intensities, where each output light intensity is obtained by processing the light intensity value of the exit light acquired by one or more photosensitive surfaces, and each photosensitive surface is used to acquire the light intensity value of the exit light exited from the exit position within a predetermined anti-jitter range corresponding to the photosensitive surface, 1?T?M; and determining a concentration of a detected tissue element according to at least one output light intensity corresponding to the predetermined wavelength.

Abstract: Aspects of the invention are drawn to a Raman spectroscopy system that incorporates a tissue probe into a thin sheath that is adapted to fit any flexible or rigid laryngoscope. The Raman probe system can comprise a probe, a laser source, an excitation signal filter, a collection filter, a charge couple device detector, a signal collection system, a housing unit, a computer, a display, or a combination thereof. In certain embodiments, the signal collection system comprises a spectrum collection range of about 200 cm-1 to about 4000 cm.

Abstract: A system useful for in vivo and ex vivo spectroscopy comprises a water source connected to supply water through a passage to an outlet at a flow rate sufficient to issue a laminar water jet from the outlet, a light source operative to emit a light beam that is guided to a sample by the water jet, and an analysis unit connected to receive collected light that has been emitted from the sample into the water jet and operable to analyze the collected light. Some embodiments provide endoscopes with integrated light guides.

Abstract: An event related optical signal, EROS, neuroimaging and analysis system for monitoring activity of a subject's brain, the system comprising: a first wavelength-swept light source configured to provide wavelength-swept emission of coherent light; and a plurality of light detectors; wherein the first wavelength-swept light source is arranged to both: (i) deliver the light towards the subject's brain tissue to be scattered to the detectors, and (ii) deliver the light to each of the detectors via one or more reference channels; wherein each of the light detectors comprises: a first input port arranged to receive scattered light from the subject's brain tissue; a second input port coupled to one of the reference channels to receive reference light from the first light source; a light combiner connected to both the first input port and the second input port for combining the scattered light received from the subject's brain tissue with the reference light received from the reference channel to provide a combined li

Abstract: A measurement system may comprise an actively illuminated camera system, in some embodiments coupled to a time-of-flight sensor or an array of laser diodes beam split into a plurality of spatially separated lights. The camera system may capture two or three dimensional images, and the light source may comprise semiconductor diodes, such as light emitting diodes. The system includes a processor coupled to non-transitory computer readable medium and configured to use artificial intelligence to make one or more decisions. The processing may also involve artificial intelligence or machine learning techniques to analyze anomalous occurrences, or generative artificial intelligence to interface with a user or improve the performance of camera-based systems. Algorithms may also be used to improve the performance of generative artificial intelligence processing. The camera output may be fused with data from other sensors, and the camera may also capture information about the pose or gestures of a user.

Abstract: A process for non-invasively analyzing a target with an analysis apparatus comprises an intensity modulation device, a light emitter emitting an intensity-modulated light, a detection cell comprising a sensor sensing directly or indirectly a thermal wave propagating out of the target in response to an irradiation of said target by the light emitted, a processor module configured to receive and process sensor data from at least one detection cell. The process comprises carrying out at least two irradiations of the target with the light emitter in a first mode, the modulation frequency of the intensity of the light emitted being swept during each of the irradiations in the first mode over a frequency sweep range, and the processor module receiving sensor data from a detection cell for each of the at least one irradiation in the first mode and forming with the processor module a time series.

Abstract: A medical device is directed to monitoring health parameters of a patient, and includes a main unit and a sensor module. The main unit includes mechanical features, a main array interface, and a processor sub-unit, which includes a processor that has communication drivers, a memory, and a sensor module. The sensor module includes a sensor unit, sensor components, enabling components, and a sensor module array interface that mates with the main array interface. In response to the sensor module being electrically and mechanically coupled to the main unit, the medical device acquires one or more bio-signals of the patient. The bio-signals correspond to an anatomic part of the patient and caries out measurements of health parameters.

Abstract: Apparatus and method for estimating blood pressure, including a plurality of sensors; and at least one processor configured to: determine situation information and posture information prior to estimation of blood pressure of a user based on data acquired using the plurality of sensors, select a cardiovascular feature from among a plurality of predetermined cardiovascular features based on the situation information and the posture information, generate a blood pressure estimation model based on the cardiovascular feature, the situation information, and the posture information, and estimate the blood pressure of the user based on the generated blood pressure estimation model.

Abstract: Disclosed is a cuffless blood pressure estimating device, which includes a hemodynamic parameter estimating circuit that measures at least two height levels based on position information output from at least one position detection sensor, measures user's bio-signals respectively at the height levels, and estimates a blood pressure from the height levels and the user's bio-signals based on a machine learning algorithm or a state estimation algorithm with a hemodynamic state space model, and at least one processor that controls the hemodynamic parameter estimating circuit.

Abstract: Methods, systems, and media for determining blood pressure measurements are provided. In some embodiments, a method for determining blood pressure measurements comprises: obtaining a set of photoplethysmography (PPG) signals using a wearable device worn by a user; determining that a blood pressure of the user is being measured by a device unassociated with the wearable device based at least in part on the set of PPG signals; responsive to determining that the blood pressure of the user is being measured by the device unassociated with the wearable device, obtaining an indication of a blood pressure measurement obtained by the device unassociated with the wearable device; and storing the obtained indication of the blood pressure measurement for future use by the wearable device.

Abstract: A novel method for assessing blood pressure stability uses a plurality of outcome parameters based on blood pressure measurements. An individual subject may be classified as of hypotensive, hypertensive, unstable, or normal based on the plurality of outcome measures, which are calculated based on a target blood pressure range and a plurality of expanding blood pressure ranges.

Abstract: A method of determining blood pressure measurements includes inflating a cuff, receiving an indication of pressure inside the cuff during inflation, determining a blood pressure based at least in part on the received indication, assigning a confidence level to the blood pressure, and determining whether the confidence level satisfies a threshold confidence level. Based at least on a determination that the confidence level satisfies a threshold confidence level, the method can include causing a display to display the blood pressure. Based at least on a determination that the confidence level does not satisfy a threshold confidence level, the method can include deflating the cuff, receiving an indication of pressure inside the cuff during deflation, determining another blood pressure, and causing a display to display a blood pressure.

Abstract: An apparatus for measuring compliance of blood vessels includes a photoplethysmography sensor for emitting electromagnetic radiation to the blood vessels, for receiving electromagnetic radiation reflected off the blood vessels, and for producing a measurement signal indicative of the received electromagnetic radiation. The apparatus further includes a pressure instrument for producing mechanical pressure applied on the blood vessels, and a control system for controlling the pressure instrument to change the mechanical pressure linearly with respect to time during emission of electromagnetic radiation to the blood vessels and reception of reflected electromagnetic radiation from the blood vessels. The control system finds, from the measurement signal, a portion whose envelope has exponential change with respect to time and produces an estimate for an exponent coefficient of time during the exponential change. The coefficient is indicative of the compliance, as well as stiffness, of the blood vessels.

Abstract: Wearable devices can be used to provide therapy to users and/or to monitor various physiological parameters of the user. In some cases, therapy can be triggered automatically based on the monitored physiological parameters reaching or exceeding predefined thresholds.

Abstract: A sensing device is provided that includes a non-flexible body that is wearable on a user's finger and a biosensor that measures biological information through the finger. The body has an inner peripheral surface facing a pad, a back, an outer side surface, and an inner side surface. The biosensor is on the inner peripheral surface to face the pad when the body is worn on the finger. In a cross-section of the inner peripheral surface, a first distance between a portion of the inner peripheral surface that faces the pad of the finger and a portion of the inner peripheral surface that faces the back of the finger is shorter than a second distance between a portion of the inner peripheral surface that faces the outer side surface of the finger and a portion of the inner peripheral surface that faces the inner side surface of the finger.

Abstract: A patient-wearable device for detecting a subpulse of a patient and determining a pulse condition based thereon, and related systems, methods and computer program products. The device includes a base layer comprising a printed circuit board (PCB) and electronics connected thereto, and an adhesive layer connected to the base layer. The electronics may include one or more sensors that generate sensor data, a computer that processes the sensor data to determine the pulse condition of the patient, and a user interface (UI) component that generates a user-perceptible indication of the determined pulse condition. In alternate embodiments, the computer and the UI component may be external to the device and the device may communicate the sensor data to the computer via wired or wireless connection. In further embodiments, multiple devices may be attached to the patient and concurrently transmit raw or processed sensor data to facilitate determination of the pulse condition.

Abstract: Methods, systems, and devices for leveraging data from multiple data sources are described. A method includes receiving physiological data associated with a user from a wearable device and receiving additional data from an external device different from the wearable device, the additional data including at least data associated with characteristics of an environment associated with the user. The method further includes identifying one or more relationships between the collected physiological data and the characteristics of the environment associated with the user, and causing a graphical user interface (GUI) of a user device to display an indication of the one or more relationships, a message associated with the one or more relationships, or both. In some cases, the method includes causing the GUI to display instructions for selectively adjusting the one or more characteristics of the environment associated with the user based on the one or more relationships.

Abstract: Provided is a non-contact blood flow observation apparatus that enables speedy and clear observation of states of blood flow in a contactless manner. This non-contact blood flow observation apparatus 1 includes an image acquirer 2 that acquires a first image 2im that is a moving image or a series of still images of a region including a blood vessel, and an image processor 3 that correlates a different color with each gradation of brightness in advance, creates a second image 3im by assigning the color corresponding to the brightness for each singular or plurality of pixels in the first image 2im, and displays the second image 3im that is a moving image or a series of still images on a display device 5.

Abstract: A system for monitoring a patient is described. The system includes a first sensor disposed at a central site, and adapted to provide a first signal; a second sensor disposed at a distal site, and adapted to provide a second signal; a processor; and a memory that stores executable instructions. When executed by the processor, the instructions cause the processor to: correlate a first perfusion index based on the first signal from the first sensor and a second perfusion index based on the second signal from the second sensor, and determine a trend based analysis of perfusion based on the first signal and in the second signal.

Abstract: Method and devices for treating a physiologic condition of a patient using measurements of pressure of an interstitial space of a patient as an indicator of required therapy.

Abstract: A device insertable into the anus of a patient for obtaining bioimpedance and/or pressure data. The data can be analyzed to treat defecation related diseases. The device may be shaped to be easily inserted and alternatively or additionally comprise a dissolvable outer shell and spongy inner portion wherein the spongy inner portion may absorb liquids and sensors disposed thereon may obtain data from the liquid. A method of use for using said devices is also described.

Abstract: An electrode harness for use in carrying out Electrical Impedance Tomography (EIT) on a human or animal subject is disclosed. The electrode harness includes an electrode support a plurality of electrodes on the electrode support for contacting a surface of an external body part of the subject, a plurality of connectors, each connector coupled to a respective electrode of the plurality of electrodes, and a control unit. The control unit includes an interrogator for coupling to the electrodes via the connectors, the interrogator being configured to selectively provide electrical signals to multiple groups of electrodes of the plurality of electrodes and for measuring, in response to the provided electrical signals, electrical response signals at at least some electrodes of the plurality of electrodes, and communication circuitry for transmitting information associated with the electrical response signals to an external computing device. A system and method are also disclosed.

Abstract: A computer-implemented method for segmenting of a human patient tractogram into one or more white matter streamline bundles by obtaining a tractogram of a human patient, the tractogram including tractogram streamlines, and a white matter atlas including one or more bundles each including respective atlas streamlines and, for at least one bundle of the atlas and its respective atlas streamlines, attributing, to the at least one bundle, respective tractogram streamlines, the respective tractogram streamlines including one or more first sets each of at least one tractogram streamline, each first set corresponds to a respective set of at least one atlas streamline of the at least one bundle, and the respective tractogram streamlines further including one or more second sets each of at least one tractogram streamline, each second set corresponds to respective sectional portion of a respective set of at least one atlas streamline of the at least one bundle.

Abstract: Disclosed is a method and system for navigating an instrument relative to a subject. A reference device can be associated with the subject. The reference device can be moved while maintaining or allowing registration with an image space.

Abstract: Systems and methods are provided for identifying and locating a plurality of RFID markers implanted within a target tissue region within a patient's body. A probe is provided that may receive signals from the RFID markers. The RFID markers modulate signals from the respective markers based on code sequences opening and closing respective switches of the markers to modulate the backscatter signals. The probe processes the signals to separate the signals based at least in part on the code sequences to identify each of the plurality of markers.

Abstract: A system includes one or more processors, a user interface, a. sensor, and a. computer readable medium storing instructions that, when executed by the one or more processors, cause the system to perform functions. The functions include generating, via the sensor, a signal representing vibrations originating from a. blood vessel of a patient and generating an intensity' spectrum of the signal that indicates intensities of the vibrations with respect to oscillation frequencies of the vibrations. The functions also include identifying a first peak of the intensity spectrum that corresponds to a respiratory' frequency of the patient and a second peak of the intensity spectrum that corresponds to a heart rate of the patient. The functions also include performing a comparison of a. first intensity of the first peak with a second intensify of the second peak and generating, via the user interface, output indicative of the comparison.

Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to a Voice Analysis Engine. According to various embodiments, the Voice Analysis Engine receives first streaming prompt data from a computing device. The Voice Analysis Engine analyzes the first streaming prompt data to provide feedback to the user of the computing device. Upon determining the first streaming prompt data satisfies one or more criteria, the Voice Analysis Engine receives second streaming prompt data from the computing device. The Voice Analysis Engine analyzes the streaming prompt data to predict a respiratory state of the user of the computing device.

Abstract: The present invention relates to a system for detection of volatile organic compounds (VOC) in exhaled breath for health monitoring. It can be used for screening, diagnosis, monitoring onset and relapse of diseases. Certain volatile compounds, in exhaled breath 5 of a person, which are the markers of the disease under consideration, will be analysed by the sensor array. The presence and concentration of these markers will be determined by a sensor array specific for the set of markers for the disease. Depending on the presence or absence and concentration levels of these VOCs health status of a person can be analysed. The present invention also relates to a device for monitoring health conditions of an 10 individual and screening for presence or relapse of diseases.

Abstract: A sampling device for air or breath samples can collect both aerosols and particles as well as volatile organic compounds (VOC's) from the air or breath sample using a single device. The obtained samples are compatible with analytical methods to determine the presence or absence of (bio)markers without the need of an extensive work-up thereby simplifying their use and the analysis of air or breath samples.

Abstract: Provided is a method for generating an assessment of a respiratory disease in a subject at a current point in time. The method comprises determining a baseline statistic relating to usage of an inhaler in a baseline period. The inhaler is configured to deliver a rescue medicament to the subject, and has a use determination system configured to determine usage of the inhaler by the subject. The method also comprises determining a current statistic relating to usage of the inhaler in a current period containing the current point in time. The method further comprises generating a comparator variable. Generating the comparator variable comprises comparing the current statistic and the baseline statistic. The assessment of the respiratory disease is based on the comparator variable.