Abstract: There is provided a polarization analysis apparatus that adjusts an angle of incidence or a numerical aperture by using an aperture. The apparatus includes: a first aperture that transmits a lighting beam reflected from a sample on a substrate; a second aperture that transmits a lighting beam having passed through the first aperture; and a detector that detects a lighting beam having passed through the second aperture and selects an angle of incidence of the lighting beam and numerical apertures of the first aperture and the second aperture.

Abstract: A process for producing a microbolometer including a vanadium-oxide-based sensitive material containing an additional chemical element chosen from arsenic, germanium, silicon and phosphorus, the process including: determining an effective amount of the additional chemical element from which the modified compound, having undergone a step of exposure to a temperature Tr for a time ?tr, exhibits an electrical resistivity ?a|r at room temperature that is higher than 10% of its native value; producing the sensitive material in a thin layer, this material being formed from the modified compound having an amount of the additional chemical element that is greater than or equal to the effective amount; and exposing the sensitive material to the temperature Tr for the time ?tr.

Abstract: An image forming device according to an embodiment includes a human sensor configured to detect a person in front of the device and an adjustment mechanism configured to move the human sensor to adjust a detection distance. A sensor cover panel is provided for an exterior of the device and is configured to cover the human sensor and the adjustment mechanism. The adjustment mechanism includes an operator element that is manually operable by a user to adjust the detection distance. The human sensor and adjustment mechanism are disposed behind the sensor cover panel. The sensor cover panel has a detection window through which a detection wave for the human sensor can pass. The sensor cover panel has an opening through which the operator element is exposed so as to be seen by a user from both the front side and a lateral side of the device.

Abstract: A sensor configured to sense heat or infrared light including a substrate includes a plurality of recess portions; a cavity inside the substrate along a bottom surface and opposing side surfaces of the substrate; a lower reflective layer disposed on at least one of an upper surface of the bottom surface of the substrate, a lower surface of the bottom surface of the substrate, and a surface opposite to the lower surface of the bottom surface of the substrate; a first electrode and a second electrode disposed inside both side surfaces of the recess portion and facing each other; a pixel structure configured to sense heat or infrared light inside the recess portion and embedded in the substrate; and a planarization layer covering the entire upper portion of the substrate.

Abstract: A temperature sensor system for an integrated circuit includes at least one sensor configured to generate a sensor signal indicative of a temperature in a respective location of the integrated circuit and a sensing module configured to receive the sensor signal, determine a temperature of the at least one sensor based on the sensor signal, an electrical characteristic of the at least one sensor, and a relationship between the electrical characteristic and the temperature of the at least one sensor, the relationship corresponding to variations in the electrical characteristic at a known calibration temperature, and generate a temperature signal based on the determined temperature.

Abstract: A method of detecting temperature of an electrical terminal. The method includes: applying a material patch to a surface of the electrical terminal, the material patch containing a polymer matrix with a polymeric positive temperature coefficient material which contains a mixture of electrically conductive magnetic particles, whereby the material patch does not appreciably increase the electrical resistance or thermal capacitance of the electrical terminal; and remotely sensing a change in the material patch with an electrically isolated circuit which is external to the electrical terminal to determine if the electrical terminal is operating at a safe temperature to optimize current flow across the electrical terminal.

Abstract: A load sensor includes: a base member being insulative and having elasticity; an electrode having elasticity and formed on an upper face of the base member; and a wire member being electrically conductive and disposed so as to be superposed on an upper face of the electrode, a surface of the wire member being covered by a dielectric body. A ratio of a thickness of the electrode to a thickness of the base member is not less than 0.02 and not greater than 0.3.

Abstract: A force-measuring device (FMD) assembly for a portable electronic apparatus includes a mid-frame including a base portion, a sidewall portion, and a transition region between the base portion and the sidewall portion, and force-measuring devices coupled to the inner surface of the sidewall portion. The sidewall portion and the transition region are elongate along a longitudinal axis. FMDs are coupled to the inner surface at respective contact regions of the sidewall portion and are separated from each other along the longitudinal axis. Each of the FMDs includes strain-sensing element(s). Each of the FMDs corresponds to a respective sense region of the sidewall portion. The transition region includes a respective elongate slit or trough for each of the sense regions. The respective elongate slit or trough is elongate along the longitudinal axis. Adjacent elongate slits or troughs are separated by a respective rib.

Abstract: A pressure-sensitive sheet for detecting a force applied to an object, the sheet comprising: a first substrate having a first electrical connection region and a first electrode region thereon, the first electrical connection region being electrically connected to the first electrode region; a second electrical connection region and a second electrode region, the second electrical connection region being electrically connected to the second electrode region, the second electrode region being physically separated from the first electrode region; a pressure-sensitive layer arranged between the first electrode region and the second electrode region to provide an electrical connection therebetween, the pressure-sensitive layer being arranged to change electrical resistance in response to pressure changes, wherein the first electrical connection region and the second electrical connection region are arranged along different edge regions of the pressure-sensitive sheet to provide circuit terminals of the first elect

Abstract: A display device includes a display panel and a first force sensor. The first force sensor is disposed adjacent to a first edge of the display panel and extends along the first edge. The first force sensor includes a plurality of first sensing regions and a second sensing region disposed closer to the second end of the first force sensor than the first sensing regions. The first sensing regions are disposed closer to a first end of the first force sensor than the second sensing region, and the second sensing region. The second sensing region is disposed closer to a second end of the first force sensor than the first sensing regions. The second sensing region has a larger area than each of the first sensing regions.

Abstract: The present invention concerns apparatus (1) for obtaining distributed pressure measurements in a wellbore (2), the apparatus (1) comprising: a flexible rod (10; 110) arranged to be disposed in the wellbore (2); and an elongate sensing member (15; 115) extending along the rod, the sensing member comprising at least one optical sensing fibre member (16; 116) arranged to afford a continuous length of sensing capability, wherein the sensing member extends in a groove formed in the exterior surface of the rod.

Abstract: A stress properties measurement method for measuring properties of stresses generated in a structure includes acquiring, from a first imaging device, a plurality of thermal images corresponding to temperatures of a surface of the structure, the plurality of thermal images being different in imaging time from each other, generating a stress distribution image corresponding to each of the plurality of thermal images, acquiring a stress value of a first section that is smaller in stress gradient than a predetermined value and respective stress values of a plurality of second sections where stresses are concentrated for the stress distribution images, and deriving correlation properties of stresses at a section of the structure based on the stress value of the first section acquired and the respective stress values of the plurality of second sections acquired.

Abstract: Described herein are techniques to enable a mobile device to perform multi-source estimation of an altitude for a location. A baseline altitude may be determined at ground level for a location and used to calibrate a barometric pressure sensor on the mobile device. The calibrated barometric pressure sensor can then estimate changes in altitude relative to ground level based on detected pressure differentials, allowing a relative altitude to ground to be determined. Baseline calibration for the barometric sensor calibration can be performed to determine an ambient ground-level barometric pressure.

Abstract: A force measurement system includes: a grinding arm and a force receiving device, the force receiving device being fixed on its one side and configured to receive a force from the grinding arm; a load cell, which is fixed on the force receiving device and configured to detect the force received by the force receiving device; and a grinding disk, which is fixed on the grinding arm that applies the force to the force receiving device through the grinding disk. The embodiments of the present application facilitate accurate acquisition of a force acting upon a grinded object during actual grinding.

Abstract: Examples extend to methods, systems, apparatus, and computer program products for detecting impacts on metal targets in a live-fire environment. In one aspect, a system determines and displays a bullet impact on a steel target. The system includes a plurality of sensors conjoined with said steel target and including at least one strain gauge for measuring data including strain on a target. A set of LED lights is conjoined with said steel target for displaying bullet impacts. The system includes a wireless transmitter adapted to transmit target impact data. The wireless transmitter is conjoined with or otherwise communicably connected to the plurality of sensors. The system includes at least one remotely located wireless receiver for receiving transmitted target impact data.

Abstract: Tactile sensing using both coarse and fine tactile sensors. A coarse tactile sensor having a first sensitive area at least partially encompasses or overlies a plurality of fine tactile sensors, each having a respective sensitive area smaller than the first sensitive area. The coarse tactile sensor(s) and fine tactile sensors may be carried on a same circuit board or separate circuit boards. Processor(s) circuits are communicatively coupled to the coarse and/or fine tactile sensors. Information indicative of at least a presence or absence of force or pressure at a given location monitored by the respective tactile sensor, and/or a measure of the force or pressure or strain is collected. Such may be mounted to a backing, and optionally covered or encased in an artificial skin. Collecting sensor readings employs both coarse and fine tactile sensors, sampling corresponding fine tactile sensors in response to detection by a coarse tactile sensor.

Abstract: The invention relates to a sensor mat (4) for an area sensor system (1.2), particularly for monitoring a room (101) of a building (100), comprising a flexible base unit (10) that has a first carrier element (11) with a planar extension and a first main side (11.1) and a second main side (11.2), and at least one detection means (30) for detecting an event (3). In addition, the invention relates to an area sensor system (1.2) for detecting an event (3), and to a method (200) for producing a sensor mat (4).

Abstract: Shaped body, in particular for a pressure sensor, having a membrane and having a supporting section supporting the membrane, the membrane being produced at least in sections from a ceramic material by means of additive manufacturing, in particular 3D screen printing, and the greatest possible distance between two points lying on the outer circumference of the membrane (12) is less than 20 mm.

Abstract: A method for determining a combustion gas composition of a combustion gas for an internal combustion engine includes operating the engine, and establishing an operating point of the internal combustion engine during operation. The method also includes detecting a nitrogen oxide emission of the internal combustion engine at the operating point. The method further includes detecting an exhaust gas temperature of the internal combustion engine at the operating point, and detecting a combustion air ratio of the internal combustion engine at the operating point. The combustion gas composition of the combustion gas is determined based on the operating point, the detected nitrogen oxide emission, the detected exhaust gas temperature and the detected combustion air ratio.

Abstract: A non-transitory computer readable medium with instructions stored thereon, the instructions executable by one or more processors for calculating base swirl in a gas turbine; and calculating relative swirl in the gas turbine. Also, a method for gas turbine maintenance, comprising identifying a combustor in need of repair or replacement within a gas turbine; and repairing or replacing the combustor; wherein said identifying comprises calculating base swirl of the gas turbine and calculating relative swirl of the gas turbine in order to associate a gas path from a thermocouple to the combustor in need of repair or replacement.

Abstract: The present invention comprises a method for detecting a leak in a vacuum assembly comprising the steps: implementation of a first detection process to identify a leak area, involving the supply of a vacuum assembly which has a plurality of sensors for detecting a parameter, the determination of values of the parameter over time during the evacuation of a cavity of the vacuum assembly, the creation of a value-time curve for each sensor of the vacuum assembly from the values detected for the respective sensors by means of an evaluation unit, the comparison of the value-time curves created with one another and identification of differences depending on the comparison by means of the evaluation unit, and the identification of a leak area in the vacuum assembly depending on the differences determined in the value-time curves and the respective position of the sensor in relation to the vacuum assembly; and implementation of a second detection process following the first detection process to detect the leak w

Abstract: Embodiments of the disclosure are drawn to apparatus and methods for determining gas flux measurements. A gas plume may be emitted from a source and may be blown by wind in an environment. A measurement system, such as a light detection and ranging (lidar) system may collect a plurality of gas concentration measurements associated with the gas plume at a plurality of locations in the environment. A gas flux may be determined based on one or more of the gas concentration measurements along with a wind speed at a location associated with the gas plume. In some embodiments, a height of the gas plume may be determined, and the wind speed at the height of the gas plume may be determined and used to determine the gas flux.

Abstract: The invention relates to a leak detection device comprising: a portable leak detection bell-like member comprising a sealing joint and configured to define a detection chamber between the main body and the test zone, the detection bell-like member further comprising a carrying handle which is provided with a control member which can be manually activated to produce a control signal, a gas suction circuit which is intended to connect the detection chamber to a vacuum pump, the gas suction circuit being provided with a controlled valve which can be switched into an open state to connect the detection chamber to the vacuum pump and a closed state to isolate the detection chamber from the vacuum pump, and a control unit which is configured to switch the controlled valve in response to the control signal.

Abstract: A sniffer probe for a leak detector for monitoring the leaktightness of an object to be tested by tracer gas includes an end piece created in the form of a rigid tube, a housing, a connection member connecting the end piece to the housing, and a sampling duct to sample a gas at a first end of the end piece. The connection member includes a main body that is elastically deformable such that it can adopt a deformed position, making it possible for the end piece to pivot when acted upon by a force and to return to the initial rest position.

Abstract: An apparatus and a method are provided for an oil filter-leak pressure-test station. The oil filter-leak pressure-test station comprises an air pump, a pressure gauge, a vent valve, an overflow reservoir, and a manifold configured to receive an oil filter. The oil filter-leak pressure-test station is configured to apply a desired internal air pressure to an oil filter for observing the oil filter assembly for any potential leaks, such as along a seal ring, rolled seam or a nut-end. The oil filter-leak pressure-test station is also configured to be mounted in a vise or similar mechanical attachment for observation to determine the extent or existence of any leak in the oil filter. The oil filter-leak pressure-test station may also be submerged in water using a submersion reservoir, so as to determine the existence and location of any leaks.

Abstract: Methods and related systems for operating a climate control system for an indoor space are disclosed. In an embodiment, the method includes operating an indoor fan of the climate control system to rotate an impeller of the indoor fan in a reverse rotational direction opposite a nominal rotational direction of the impeller. Additionally, the method includes determining an airflow of the indoor fan when the impeller of the indoor fan is rotated in the reverse rotational direction. Further, the method includes determining a duct leakage rate associated with at least one duct of the climate control system based on the determined airflow, wherein the at least one duct is sealed-off at an end thereof.

Abstract: A system and method for monitoring conditions in a crawl space is provided. The system generally comprises at least one sensor, computing device, data aggregator operably connected to the at least one sensor, processor operably connected to the computing device, power supply, and non-transitory computer-readable medium coupled to the processor and having instructions stored thereon. The system is designed to collect condition data via the at least one sensor and determine whether the conditions within the crawl space could have a detrimental impact on the building. In particular, the system is designed to alert a third-party when a condition might cause damage to a building so that the third-party might correct the cause of the condition.

Abstract: An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.

Abstract: A gas sampling trap includes a first stage and a second stage. The first stage includes a metal salt that reacts with sulfurous species to produce acidic gas. The second stage configured to receive the acidic gas produced in the first stage. An adsorbent substrate in the second stage adsorbs the acidic gas. A method of sampling a gas includes directing gas onto a metal stage within a first stage to produce acidic gas, directing the acidic gas into the second stage, and adsorbing the acidic gas in the second stage with an adsorbent substrate. A method of detecting a concentration of sulfurous species in a gas includes sampling the gas with a sampling trap, desorbing adsorbed acidic gas from an adsorbent substrate of the sampling trap with a solvent, and testing the solvent with ion chromatography.

Abstract: In a method for analyzing samples of a gas in a rotary cement kiln by at least one gas sampling probe, a first and a second gas sampling probe are provided, wherein the first gas sampling probe is moved so as to reach a sampling position, wherein gas samples are withdrawn from the kiln and analyzed by the first gas sampling probe being in the sampling position, while the second gas sampling probe is kept in a retracted position and is purged, whereupon the second gas sampling probe is moved so as to reach a sampling position, and the first gas sampling probe is moved from the sampling position to the retracted position and is purged, while gas samples are withdrawn from the kiln and analyzed by the second gas sampling probe being in the sampling position.

Abstract: A system for processing biological or other samples includes an array of transducer elements that are positioned to align with sample wells in a microplate. Each transducer element produces ultrasound energy that is focused towards a well of the microplate with sufficient acoustic pressure to cause inertial cavitation. In one embodiment, the transducers are configured to direct ultrasound energy into cylindrical wells. In other embodiments, the transducer elements are configured to direct ultrasound energy into non-cylindrical wells of a microplate.

Abstract: A system for preserving a surgically explanted tissue sample has a first packing station for placing the tissue sample in a selected container among a plurality of containers of different sizes. Each container has a hermetic lid (50) with an opening (33) equipped with a non-return valve (51). The system also has a final packing station equipped with a filling system for filling the selected container with a preservative substance, including a nozzle-holding head (28) mounted movable on a vertical guide (29). A method is also described which provides for the selection of the container based on the evaluation of the volume of the tissue sample, the hermetic closure of the container immediately after the insertion of the tissue sample. and the filling of the container by means of a nozzle (31) of a filling system inserted in the non-return valve (51) of the hermetic lid (50).

Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.

Abstract: The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell. The invention in general provides novel methods for the traceless isolation of biologic materials such as cells, cell organelles, viruses and the like. The invention also relates to an apparatus for the isolation of cells and other complex biological materials.

Abstract: A time-varying detecting device and method for concrete rheological parameters, in which the double-covered cylinder has top and bottom covers (11, 12), both of which can be freely opened, is configured to contain a concrete sample, and a lifting frame includes a pair of vertical supports (21) extending in parallel with each other. The double-covered cylindrical container is held between the pair of vertical supports (21) by means of connecting members (30) in such a manner that it can be flipped 180° about a straight line along which the connecting members (30) extend under the action of an external force. To perform a test, the top cover (11) is opened and a concrete mix is filled in, followed by detecting initial rheological parameters. The top cover (11) is closed, and the concrete mix is left for a predetermined period of time. The double-covered cylindrical container is lifted to a predetermined height by raising the connecting members (30), flipped 180° and lowered back onto the floor.

Abstract: Time multiplexing an electromagnetic trap beam may be used to generate trap shapes/geometries to trap one or more particles with one electromagnetic beam by directing the electromagnetic beam at a pattern of different locations with sufficient rapidity to form an effective shape/geometry. Additionally, multiplexing an electromagnetic trap beam may be used to shutter trapping electromagnetic radiation to protect a viewer, use the same beam for multiple functions, move and organize particles, and generate illumination effects.

Abstract: A Compact Optical Virus Detection Analyzer (COVDA) uses light scattering and fluorescence to detect nanometer (nm) and micrometer (um) sized particles, such as biological particles and can be used to detect viruses such as coronavirus including SAR-CoV-2 responsible for COVID-19, pollen and bacteria. It can be used for prescreening, rapid detection of suspicious people. COVDA involves experimental and theoretical methods for particle and virus detection using Tryptophan as a key biomarker.

Abstract: Synthetic human cell mimic hydrogel particles and their use in cytometric or coulter device applications are described. The synthetic human cell mimic hydrogel particles described herein are selectively tunable to have at least one optical, volumetric, or capacitance property that is substantially similar to a corresponding optical, volumetric, or capacitance property of the human cell mimic hydrogel particle's natural biological cell counterpart.

Abstract: The present disclosure relates to a flow cell carrier. The flow cell carrier may include a flow cell and a frame. The frame may include a pocket and a handle. The pocket may have at least one spring feature and at least one banking feature. The frame may be configured to retain the flow cell within the pocket such that a maximal surface area of the flow cell is exposed to an optical lens. Related methods and kits are also disclosed.

Abstract: An apparatus for detecting a processing tool defect is provided. The apparatus includes a processing tool having a processing chamber configured to process a semiconductor wafer. The processing chamber includes a gas inlet and a gas outlet. An exhaust pipe is connected to the gas outlet of the processing chamber. A particle counter is configured to real-time measure a parameter of particles in the exhaust pipe. A method for detecting a processing tool defect is also provided in the present disclosure.

Abstract: According to an aspect of the present inventive concept there is provided a light excitation and collection device for a micro-fluidic system, comprising: a light source configured to generate excitation light; a plurality of excitation waveguides, each associated with a flow channel of the micro-fluidic system; wherein each excitation waveguide is configured to receive and redirect the excitation light towards the flow channel, such that the excitation light is elastically scattered by a sample in the flow channel forming forward and side scattered light; and wherein the light excitation and collection device further comprises: at least one forward scattered light collection point; and at least one side scattered light collection point; and wherein the forward scattered light collected for all excitation waveguides is detected by a first plurality of light sensitive areas and the side scattered light collected for all excitation waveguides is detected by a second plurality of light sensitive areas, the fi

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: Provided is a measurement method for measuring a size of a damaged portion in a coated metal material that includes a metal base and surface treatment film provided on the metal base, and reaching the metal base through the surface treatment film. The measurement method includes the steps of disposing a water-containing material to be in contact with the damaged portion and an electrode to be in contact with the water-containing material, and electrically connecting between the electrode and the metal base with an external circuit; applying, with the external circuit, a constant voltage between the electrode and the metal base, as a cathode and an anode, respectively, and measuring a current value flowing therebetween; and calculating a size of the damaged portion, based on the current value measured and a correlation between the current value and the size of the damaged portion, determined on an exploratory basis in advance.

Abstract: The invention relates to an optical flow cell comprising a housing forming an enclosed and elongated fluid channel arranged along a first axis, an inlet arranged to connect a first outer surface area of the housing to a first end of the fluid channel and an outlet arranged to connect a second outer surface area to a second end of the fluid channel, a first light guide and a second light guide concentrically arranged along a second axis and on opposite side walls of the fluid channel. The invention further relates to a corresponding method to produce an optical flow cell.

Abstract: A device, for emitting and controlling infrared light, comprises a substrate extending between a bottom surface and a top surface. A cavity is provided in the substrate, the cavity opening onto the top surface. A light source extends over the cavity and is able to heat up when passed through by an electric current, so as to emit infrared light. A cover covers the substrate, the cover and the substrate forming a first component enclosing the light source. The light source delineates a first half space comprising the cover, and a second half space comprising the cavity and the bottom surface of the substrate.

Abstract: An apparatus for analyzing a material includes an excitation emission device for generating at least one electromagnetic excitation beam, in particular an exciting light beam, having at least one excitation wavelength, further comprising a detection device for detecting a reaction signal, and a device for analyzing the material on the basis of the detected reaction signal.

Abstract: A sensing apparatus that senses structure of electrode of electrical battery. The electrode is arranged to have layers spatially adjacent thereto that provide a waveguide region that includes a surface of the electrode that changes in structure. The sensing apparatus includes a source of Terahertz electromagnetic radiation, and a coupling arrangement that couples Terahertz electromagnetic radiation from the source into the waveguide region. The Terahertz electromagnetic radiation interacts with features present at the surface. The sensing apparatus includes detector that receives Terahertz electromagnetic radiation that is reflected and/or transmitted through the waveguide region, and processes the Terahertz electromagnetic radiation to determine temporal changes therein that are indicative of dendritic growths occurring at the surface of the electrode or any manufacturing or structural faults.

Abstract: Methods and systems for determining water status in plant tissue are provided. A number of systems are capable of using terahertz signals to generate signals measuring total water content in plant tissue, including plant leaves. Using these signals, methods are capable of determining water status variables, including water mass per leaf area, relative water content, and leaf water potential, which can aid in agricultural, ecological, and environmental health, such as dehydration and droughst stress of plants.

Abstract: An optical measuring device for the spectral measurement of a sample is disclosed. The optical measure device includes an integrating cavity that has a diffusely reflective interior in order to render the light in the integrating cavity diffuse, a light source that is configured to emit light of a predetermined wavelength range into the integrating cavity, and a sensor that is configured to receive light from the integrating cavity, wherein the integrating cavity comprises an optical opening, and wherein the optical measuring device is provided and configured to measure a sample located outside of the integrating cavity directly in front of the optical opening.

Abstract: Described herein are novel rapid and reliable methods of detection of extracellular vesicles and quantifying extracellular vesicle concentrations and absolute number from various sources, including raw cell harvest. The methods described herein comprise detection of light scattering of extracellular vesicles in biological samples. Extracellular vesicles analyzed by the methods of this application have a stereotypical elution profile distinct from known contaminants. The methods described herein are a significant improvement over the state of the art and fulfills an unmet need in the field of extracellular vesicle manufacturing and quality control.