Patents Issued in September 12, 2024
  • Publication number: 20240299908
    Abstract: A polymer including reacted units of 1,3,5-trihydroxybenzene and a compound A represented by Formula (I) below, in Formula (I), n=0-5. Compound A is bonded to the 1,3,5-trihydroxybenzene through an azo bond to form the polymer, represented by Formula (II) below, Formula (II), represents a repeating unit of the polymer.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 12, 2024
    Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventors: Mahmoud Mohamed ABDELNABY, Tawfik Abdo SALEH
  • Publication number: 20240299909
    Abstract: A method for removing a contaminant from an environment is described comprising the steps of: (i) heating a reduced and passivated getter material containing crystallites of a metal in elemental form encapsulated by a layer comprising an oxide of the metal to a temperature in the range (TT?X) to (TT+Y), where TT is the Tammann temperature of the metal in elemental form in degrees Centigrade, X is 400 and Y is 200, to form an activated getter material having active surface for contaminant removal and (ii) exposing the activated getter material to the environment containing the contaminant.
    Type: Application
    Filed: March 3, 2022
    Publication date: September 12, 2024
    Inventors: Alan BOOTLAND, Mikael CARLSSON, David DAVIS, Jonathon HIGGINS, Andrew Edward RICHARDSON, Emma SOFTLEY, John WEST
  • Publication number: 20240299910
    Abstract: A method of preparing a catalyst comprising a) drying a chrominated-silica support followed by contacting with a titanium(IV) alkoxide to form a metalized support, b) drying a metalized support followed by contacting with an aqueous alkaline solution comprising from about 3 wt. % to about 20 wt. % of a nitrogen-containing compound to form a hydrolyzed metalized support, and c) drying the hydrolyzed metalized support followed by calcination at a temperature in a range of from about 400° C. to about 1000° C. and maintaining the temperature in the range of from about 400° C. to about 1000° C. for a time period of from about 1 minute to about 24 hours to form the catalyst.
    Type: Application
    Filed: May 3, 2024
    Publication date: September 12, 2024
    Inventors: Max P. McDaniel, Kathy S. Clear, Eric D. Schwerdtfeger, Jeremy M. Praetorius
  • Publication number: 20240299911
    Abstract: In one aspect, the disclosure relates to an oxide-molten salt (OMS) composite material offering excellent energy storage capacity at low cost. The OMS composite material can be provided in at least three forms, including a porous, perovskite-oxide particle as a matrix having pores filled with unary salt or salt mixtures; an external shell of perovskite-oxide particles and an internal core of salt or a salt mixture; and/or a porous, perovskite-oxide particle as a matrix filled with unary salt or salt mixtures, wherein the whole particle is enclosed with an oxide outer shell. Further in this aspect, the outer shell can be dense but either mixed ionic-electronically conductive or porous. In another aspect, the disclosed methods and systems can be used for grid-scale energy storage by retrofitting existing steam turbine-based power plants and concentrated solar plants. In a further aspect, the disclosed methods, systems, and materials are environmentally benign.
    Type: Application
    Filed: March 4, 2024
    Publication date: September 12, 2024
    Inventors: Fanxing Li, Runxia Cai, Luke Michael Neal, Kevser Hilal Bektas
  • Publication number: 20240299912
    Abstract: Disclosed is a method for providing improved hydrogenation activity by pretreating a catalyst in a three-step manner before selective hydrogenation of unsaturated hydrocarbons in an aromatic fraction in the presence of an oxide-type bimetallic (particularly nickel-molybdenum) supported catalyst.
    Type: Application
    Filed: May 21, 2024
    Publication date: September 12, 2024
    Inventors: Sang Il Lee, Ji Hoon Lee
  • Publication number: 20240299913
    Abstract: Provided are a lignin degradation catalyst that exhibits excellent lignin degradability and that is readily separated after degradation reaction, a method for producing the catalyst, and a method for degrading lignin. The lignin degradation catalyst according to the present invention contains a substrate and at least one metal compound immobilized on the substrate, wherein the at least one metal compound contains a copper compound. The method for producing a lignin degradation catalyst according to the present invention includes the step of brining a porous copper substrate into contact with a solution containing an oxidant to obtain a substrate having a copper compound immobilized thereon, or the step of subjecting a porous copper substrate to electro-oxidation to obtain a substrate having a copper compound immobilized thereon.
    Type: Application
    Filed: December 27, 2021
    Publication date: September 12, 2024
    Applicants: HIROSAKI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Akihiro Yoshida, Tomonori Sonoki, Kurnia Irwan, Guoqing Guan, Abuliti Abudula, Takao Masuda, Takuya Yoshikawa
  • Publication number: 20240299914
    Abstract: Presented is a process for the preparation of zeolitic material through condensed gel crystallizations. The present disclosure describes methods for improved preparation of zeolites by preparing an aqueous precursor mixture; removing at least 5 wt % of the total water from the aqueous precursor solution to create a solution with greater solids content; crystallizing the solution of step (b) to create a zeolite product. The resulting zeolites can show improved mesoporosity without any post-treatment to create mesoporosity. This effect is particularly prominent in ZSM-5 zeolites, for example.
    Type: Application
    Filed: January 14, 2022
    Publication date: September 12, 2024
    Inventors: Daniel EVANS, James J STROHM, Heng DAI
  • Publication number: 20240299915
    Abstract: Methods of making hydrotreating catalysts are provided having one or more phosphorus components carried on a composite support of a titanium-loaded binder component and post-framework modified ultra-stable Y-type zeolite. The support comprises the titanium-loaded binder component and a post-framework modified ultra-stable Y-type (USY) zeolite. The active components including the phosphorous active component and one or more hydrocracking metals active components loaded on the support.
    Type: Application
    Filed: May 3, 2024
    Publication date: September 12, 2024
    Applicants: Saudi Arabian Oil Company, JGC Catalysts & Chemicals Ltd., Japan Cooperation Center for Petroleum and Sustainable Energy
    Inventors: Omer Refa KOSEOGLU, Robert Peter HODGKINS, Yusuke MATSUMOTO, Koji UCHIDA, Naoya KOJIMA
  • Publication number: 20240299916
    Abstract: A process for upgrading a hydrocarbon feed comprises contacting the hydrocarbon feed with steam in the presence of a cracking catalyst composition at reaction conditions sufficient to cause at least a portion of hydrocarbons in the hydrocarbon feed to undergo one or more cracking reactions to produce a steam catalytic cracking effluent comprising light olefins, light aromatic compounds, or both, where: the cracking catalyst composition comprises a cracking additive comprising a ZSM-5 zeolite, a first metal species, and a second metal species, where the first metal species and the second metal species are impregnated onto the ZSM-5 zeolite, the first metal species comprises a metal or metal oxide comprising a first metal, the second metal species comprises a metal or metal oxide comprising a second metal, and the second metal is different from the first metal.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 12, 2024
    Applicants: Saudi Arabian Oil Company, King Fahd University of Petroleum and Minerals
    Inventors: Aaron Chi Akah, Musaed Salem Al-Ghrami, Abdullah Mohammed Aitani, Ziyauddin Qureshi, Mohammed Abdul Bari Siddiqui
  • Publication number: 20240299917
    Abstract: A method is disclosed for producing small crystal forms of zeolite SSZ-81. The method includes forming a reaction mixture containing an alumina-coated silica sol, a source of an alkali metal, a structure directing agent containing 1,5-bis(N-methylpiperidinium)pentane dications and/or 1,5-bis(1-azonia-bicyclo[2.2.2]octane)pentane dications, a source of hydroxide ions, and water; and subjecting the reaction mixture to crystallization conditions sufficient to form crystals of the zeolite. The compositions made according to that method, as well as the various uses of the compositions, are also disclosed.
    Type: Application
    Filed: March 2, 2023
    Publication date: September 12, 2024
    Inventors: Christopher Michael LEW, Rebecca Edyne MACLEAN, Kurt Owen JENSEN
  • Publication number: 20240299918
    Abstract: A hydroisomerization catalyst comprising a molecular sieve belonging to the ZSM-48 family of zeolites; an inorganic oxide support; one or more first modifiers selected from Groups 8 to 10; and one or more second modifiers selected from the group consisting of calcium (Ca), chromium (Cr), magnesium (Mg), lanthanum (La), barium (Ba), praseodymium (Pr), strontium (Sr), potassium (K) and neodymium (Nd). The molecular sieve comprises: a silicon oxide to aluminum oxide mole ratio of about 40 to about 220; at least about 70% polytype 6 of the total ZSM-48-type material present in the product; and an additional EUO-type molecular sieve phase in an amount of between about 0 and about 7.0 percent by weight of the total product. The molecular sieve has a morphology characterized as polycrystalline aggregates comprising crystallites collectively having an average aspect ratio of between about 1 and about 8.
    Type: Application
    Filed: January 13, 2022
    Publication date: September 12, 2024
    Applicant: CHEVRON U.S.A. Inc.
    Inventors: Yihua ZHANG, Adeola OJO, Guan-Dao LEI
  • Publication number: 20240299919
    Abstract: A catalyst for a hydrogenation reaction including: a polymer support; and a catalytic component supported on the polymer support. The polymer support comprises a repeating unit represented by Formula 1.
    Type: Application
    Filed: May 15, 2024
    Publication date: September 12, 2024
    Inventors: Myungji Suh, Dong Hyun Ko, Minkee Choi, Songhyun Lee
  • Publication number: 20240299920
    Abstract: Exemplary catalysts may comprise a two-dimensional substrate and at least one organometallic compound bonded to the two-dimensional substrate. The at least one organometallic compound may comprise a carbonyl group. Exemplary methods of preparing a polymer product may comprise combining a catalyst with an alcohol and an ester in a solvent, thereby generating a mixture, and obtaining the polymer product from the mixture.
    Type: Application
    Filed: March 8, 2022
    Publication date: September 12, 2024
    Inventors: Wei Gao, Nanfei He, Ki Hong, Richard Kotek, Shradha V. Patil
  • Publication number: 20240299921
    Abstract: Catalyst systems suitable for tetramerizing ethylene to form 1-octene may include a catalyst including a chromium compound coordinated with a ligand and a co-catalyst including an organoaluminum compound. The ligand may have a chemical structure according to Formula (1), wherein R1 is a (C3-C20) substituted or unsubstituted hydrocarbyl group; R2, R3, R4, and R5 are independently chosen from (C1-C50) hydrocarbyl groups; and R1 and N are in a cis configuration.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 12, 2024
    Applicant: Saudi Arabian Oil Company
    Inventors: Sibo Lin, Dana Amber Wong, Yagnaseni Ghosh, Motaz Khawaji, Wei Xu, Mohamed Elanany
  • Publication number: 20240299922
    Abstract: A method is disclosed for making a catalyzed particulate filter with high clean filtration efficiency which may include applying a catalyst material to a filter body having porous filter walls, wherein filtration material comprising filtration particles are disposed on or in or both on and in porous filter walls, and the filtration material is hydrophobic while the catalyst material is applied. A catalyzed particulate filter with high clean filtration efficiency is also disclosed wherein the filter includes porous filter walls with filtration particles disposed on or in or both on and in the porous filter walls, and catalyst material disposed on or in or both on and in the porous filter walls, and wherein the catalyst material substantially does not touch the filtration particles.
    Type: Application
    Filed: January 14, 2022
    Publication date: September 12, 2024
    Inventors: Vishwanath Ganpat Deshmane, Christophe Michel Remy
  • Publication number: 20240299923
    Abstract: Disclosed are a hydrogenation catalyst, a preparation method therefor and use thereof. The hydrogenation catalyst includes a carrier and an active component supported on the carrier, wherein the carrier is nitrogen-doped carbon, and the active component is a bimetal selected from Ru—Fe, Ru—Co, Ru—Ni or Ru—Cu.
    Type: Application
    Filed: April 9, 2021
    Publication date: September 12, 2024
    Applicant: INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Liguo WANG, Huanhuan YANG, Huiquan LI, Shuang XU, Yan CAO
  • Publication number: 20240299924
    Abstract: The catalyst for methane reformation according to an exemplary embodiment of the present application comprises: a porous metal support; a first coating layer provided on the porous metal support and comprising an inorganic oxide; and a second coating layer provided on the first coating layer and comprising the perovskite-based compound represented by Chemical Formula 2: Sr1-xAxTi?ByO3-???[Chemical Formula 2] wherein all the variables are described herein.
    Type: Application
    Filed: August 1, 2022
    Publication date: September 12, 2024
    Applicant: LG Chem, Ltd.
    Inventors: Jun Yeon Cho, Sojin Kim, Suji Kim, Jun Seon Choi, Sangjin Kim, Jae Soon Choi
  • Publication number: 20240299925
    Abstract: A vacuum aspirator is shown that includes an integrated pipetting function, which device may be used for handling liquids, especially to exchange or remove liquids or liquid residues in biosciences, biomedical sciences, chemistry, materials science. The air displacement pipette includes i) a suction conduit adapted for being fluidly connected to a suction unit; and ii) a valve adapted for controlling the fluid flow through the suction conduit.
    Type: Application
    Filed: February 22, 2022
    Publication date: September 12, 2024
    Inventor: Dang Quang Svend Le
  • Publication number: 20240299926
    Abstract: A metering head for receiving and metering at least one medium, the metering head including: —one or multiple media access points; —at least two dispensing terminals each having at least one media outlet; and —fluid lines, which connect the one or multiple media access points to the at least one media outlet of the at least two dispensing terminals. In at least one of the fluid lines, an actively controllable element for manipulating and/or detecting the medium in the fluid lines is inserted. A fluidic system, including: —a metering head of this type; —a microfluidic cartridge; and —at least one connecting element for fluidically connecting the metering head to the microfluidic cartridge. The dispensing terminal is designed to indirectly or directly receive the connecting element. The microfluidic cartridge includes: —at least one inlet opening for connecting to the at least one connecting element; and —a channel structure fluidically connected to the inlet opening.
    Type: Application
    Filed: May 4, 2022
    Publication date: September 12, 2024
    Inventors: Christian FREESE, Peter SPANG
  • Publication number: 20240299927
    Abstract: Techniques for treating a detrimental physical condition are disclosed. In one embodiment, a method includes processing one or more samples obtained from the individual through use of one or more microfluidic chips to provide data indicating one or more constituents present within the one or more samples, and processing the data to determine a quantity of at least one constituent that indicates the detrimental physical condition of the individual. Next, the method determines at least one dosage of at least one treatment agent for mitigation of the detrimental physical condition based on the quantity of the at least one constituent that indicates the detrimental physical condition, and facilitates an administration of the at least one dosage for mitigation of the detrimental physical condition.
    Type: Application
    Filed: May 15, 2024
    Publication date: September 12, 2024
    Applicant: Inflammatix, Inc.
    Inventors: Edward K.Y. Jung, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, JR., Lowell L. Wood, JR.
  • Publication number: 20240299928
    Abstract: Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.
    Type: Application
    Filed: January 15, 2024
    Publication date: September 12, 2024
    Inventors: Daniel R. Wiederin, Austin Schultz
  • Publication number: 20240299929
    Abstract: The bioreactor system including a compartmentalizing device and subsequent machinery that enable advanced conditions for cell-free synthesis and/or posttranslational modifications, continuity of the purification and/or production process and/or reuse of cell-free production components is described herein. The bioreactor system enables interaction of each product making compartment that contains cell-free production mixture with providing platforms that contain supporting fluids. Methods of producing biological products by utilizing the bioreactor system are provided. Methods of manufacturing a bioreactor system is also described.
    Type: Application
    Filed: March 6, 2024
    Publication date: September 12, 2024
    Inventors: Tamara Krstic, Rakesh Mishra
  • Publication number: 20240299930
    Abstract: Two-phase flushing systems and methods. An example method includes moving a valve to a first position to fluidly connect a first reagent reservoir containing a first reagent to a flow cell and flowing the first reagent from the first reagent reservoir to the flow cell to perform a biochemical reaction. The method includes moving the valve to a second position to fluidly connect a gas to the flow cell and flowing gas into the flow cell to expel at least a portion of the first reagent from the biochemical reaction from the flow cell. The method includes moving the valve to a third position to fluidly connect a buffer reagent reservoir containing a buffer reagent to the flow cell and flowing the buffer reagent into the flow cell.
    Type: Application
    Filed: May 20, 2024
    Publication date: September 12, 2024
    Inventors: Nicholas Watson, Wesley A. Cox-Muranami, Cyril Delattre, Minsoung Rhee
  • Publication number: 20240299931
    Abstract: This disclosure provides systems and methods for the production of formulations of active pharmaceutical ingredients (APIs). In some embodiments, the disclosure provides an automated medicine formulation system comprising a portable and self-contained API formulating apparatus where the API and excipients are formulated to make a drug product meeting drug quality and safety specifications. The automated formulation system produces liquid formulations including, for example, injectable and intravenous medicines. The systems are capable of producing a plurality of individual sterile injectable doses of drug comprising a specific API and excipient(s), which can be formulated on demand in a GMP and FDA acceptable manner.
    Type: Application
    Filed: May 16, 2024
    Publication date: September 12, 2024
    Inventors: Mahdi Ramezani, Akshaya Nair, Gordon Brezicki, Jonathan Samuel, Alec Nicewick, Griffin Whittredge
  • Publication number: 20240299932
    Abstract: The present invention relates to microfluidic fluidic devices, methods and systems for use in identifying epigenetic signatures in a range of sample types, e.g., cells established on a “chip” (including but not limited to single cell samples, cell populations, cell layers and whole tissues, such as a biopsy), immune cells, cfDNA, exosomes, and the like. More specifically, in some embodiments, a microfluidic chip containing a sample is contacted with a test compound (e.g. DNA altering test compound, an RNA expression altering test compound, etc.) for use in providing a diagnostic epigenetic signature for that type of sample (or cell type) exposed to that specific test compound. In some embodiments, after contact with a test compound, effluent fluids (e.g. fluids exiting the “chip” that contacted the cells) are derived for testing as a “virtual blood draw.
    Type: Application
    Filed: May 9, 2024
    Publication date: September 12, 2024
    Inventors: Catherine Karalis, Ville Kujala
  • Publication number: 20240299933
    Abstract: Provided are a microfluidic chip and a usage method thereof, and a microfluidic system. The microfluidic chip includes a substrate layer, the substrate layer includes a substrate and a drive electrode layer; and a cover plate layer arranged opposite the substrate layer, a space between the cover plate layer and the substrate layer form a solution accommodating space; the cover plate layer includes a solution inlet hole, a solution outlet hole, and limiting recesses arranged on a side of the cover plate layer facing the substrate layer, the solution inlet hole, the solution outlet hole and each limiting recess are in communication with the solution accommodating space, and an end surface of the solution inlet hole adjacent to the substrate layer, an end surface of the solution outlet hole adjacent to the substrate layer, and opening surfaces of the plurality of limiting recesses are arranged substantially flush with one another.
    Type: Application
    Filed: March 15, 2022
    Publication date: September 12, 2024
    Inventors: Kang PENG, Ding DING, Zhukai LIU
  • Publication number: 20240299934
    Abstract: The present disclosure provides a micro-fluidic chip and a reaction system. The micro-fluidic chip includes: a base substrate; a micro-cavity defining layer on the base substrate and defining a plurality of micro-reaction chambers; a cover plate on a side of the micro-cavity defining layer away from the base substrate; a heating layer disposed between the micro-cavity defining layer and one of the base substrate and the cover plate, and configured to heat the plurality of micro-reaction chambers. One of the base substrate and the cover plate, which is away from the heating layer, has a first surface and a second surface, the first surface faces the heating layer, the second surface faces away from the heating layer, and a area of the second surface is larger than that of the first surface.
    Type: Application
    Filed: April 27, 2022
    Publication date: September 12, 2024
    Inventors: Ji PENG, Ding DING
  • Publication number: 20240299935
    Abstract: A reagent delivery and analysis system for receiving and analyzing a fluidic sample is provided. The system includes one or more reagent storage containers for holding the same or different reagents. A fluidic mixer is coupled to the one or more containers, each container coupled to the fluidic mixer via a different reagent conduit. Each reagent conduit includes a valve controlling flow of reagent from the container to the fluidic mixer. The fluidic mixer is further coupled to a fluid source. The fluidic mixer homogenizes a fluidic sample from the fluid source with reagent. A pressurization module selectively applies a pressure to at least one of the one or more containers via a pressurization fluid that is kept separate from the sample fluid, and to the reagent in the one or more containers. The pressure causes reagent to flow from a selected container into the fluidic mixer.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 12, 2024
    Inventors: Dan E. Angelescu, Joyce Wong
  • Publication number: 20240299936
    Abstract: Well assemblies enabling optical access therein and related systems and methods are disclosed. In accordance with an implementation, an apparatus includes a body, dry reagent, and a cover. The body defines a well and has an opening, an aperture, and a field of view (FOV) enabling optical access from the aperture to the well. The dry reagent is contained within the well. The cover is coupled to the body and covering the opening.
    Type: Application
    Filed: March 1, 2022
    Publication date: September 12, 2024
    Inventors: Paul Crivelli, Justin Davidson, Sébastien Ricoult
  • Publication number: 20240299937
    Abstract: A modular lab-on-a-chip device for the analysis of a fluid including at least a base module, an end module and one or more analysis modules is described. Each module includes a respective first conduit and a respective second conduit. The first conduits define at least partially a first portion and the second conduits define at least partially a second portion of a fluidic channel. The end module includes a connecting conduit connecting the first portion and the second portion of the fluidic conduit to each other; and each analysis module includes a respective analysis conduit in fluidic connection with the respective first conduit and a sensor unit configured to determine at least one characteristic of the fluid and/or components present in the fluid when the fluid is present, in use, in the analysis conduit.
    Type: Application
    Filed: March 23, 2022
    Publication date: September 12, 2024
    Applicant: Sanchip Societa' A Responsabilita' Limitata
    Inventors: Denise Pezzuoli, Marco Cozzolino
  • Publication number: 20240299938
    Abstract: An analyzer system includes a motor, a dock coupled to the motor, and a cartridge held in the dock. The cartridge includes a fluid circuit configured to receive a sample, isolate a target analyte of the sample, and collect a quantity of a first label that is proportional to a quantity of the target analyte in the sample. The fluid circuit includes a sample port configured to receive a sample, a mixing chamber in fluid communication with the sample port, and a fluid inlet port in fluid communication with the mixing chamber. The fluid circuit includes an isolated path extending from the fluid inlet port to the mixing chamber. The system also includes a fluid delivery line configured to be coupled to the fluid inlet port so as to deliver fluid to the cartridge through the fluid inlet port and push the fluid along the isolated path toward the mixing chamber.
    Type: Application
    Filed: March 6, 2024
    Publication date: September 12, 2024
    Inventors: John David Jolly, Michele Gilbert, Richard Livingston, Luis H. Monsalve, Brian W. Noland, Daniel Sheehan, Cathleen Zimmerman, William E. Ortyn
  • Publication number: 20240299939
    Abstract: Embodiments described herein generally relate to apparatuses, cartridges, and pumps for peristaltic pumping of fluids and associated methods, systems, and devices. The pumping of fluids is, in certain cases, an important aspect of a variety of applications, such as bioanalytical applications (e.g., biological sample analysis, sequencing, identification). The inventive features described herein may, in some embodiments, provide an ability to pump fluids in ways that combine certain advantages of robotic fluid handling systems (e.g., automation, programmability, configurability, flexibility) with certain advantages of microfluidics (e.g., small fluid volumes with high fluid resolution, precision, monolithic consumables, limiting of the wetting of components to consumables).
    Type: Application
    Filed: May 21, 2024
    Publication date: September 12, 2024
    Inventors: Jonathan M. Rothberg, Jonathan C. Schultz, John H. Leamon, Todd Roswech, Xiaoxiao Ma
  • Publication number: 20240299940
    Abstract: The present disclosure is drawn to devices and systems for target detection in samples, including food samples, clinical samples, environmental samples and veterinary samples. The target detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system.
    Type: Application
    Filed: January 6, 2022
    Publication date: September 12, 2024
    Inventors: Adi Gilboa-Geffen, Renuka Babu Brown
  • Publication number: 20240299941
    Abstract: Selectively vented biological assay devices and methods of performing biological assays with such devices are provided herein. Disclosed devices include a selective venting clement having passively tunable porosity. The methods include controlling fluid flow within the subject devices with the selective venting element.
    Type: Application
    Filed: May 1, 2024
    Publication date: September 12, 2024
    Inventors: Debkishore Mitra, Frank B. Myers III, John Robert Waldeisen, Ivan Krastev Dimov
  • Publication number: 20240299942
    Abstract: A microfluidic device includes a chamber having a floor, a ceiling, and an inlet. The microfluidic device includes pillars extending from the floor to the ceiling of the chamber. Each pillar has a leading surface or corner, a trailing surface or corner opposite the leading surface or corner, and trailing side surfaces adjoining the trailing surface or corner. Each pillar is oriented along a corresponding ray intersecting the leading surface or corner and the trailing surface or corner. Adjacent pillars have a turn angle between the corresponding rays of the adjacent pillars, and each pillar has a pillar angle between the trailing side surfaces thereof. The turn and pillar angles are based on a fluidic contact angle to promote fluid flow from the inlet throughout the chamber during priming without fluidic pinning.
    Type: Application
    Filed: June 30, 2021
    Publication date: September 12, 2024
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Carson Denison, Pavel Kornilovich, Alexander Govyadinov, Erik D. Torniainen, Richard W. Seaver, Anand Samuel Jebakumar
  • Publication number: 20240299943
    Abstract: The disclosure relates to a paper based microfluidic diagnostic device, which may include a top panel comprising a first plurality of cut regions and a bottom panel comprising a second plurality of cut regions, wherein the first and second plurality of cut regions are configured to form a plurality diagnostic wells, each of the diagnostic wells comprises a diagnostic paper layer positioned over a filter paper layer, the diagnostic paper layer comprises one or more diagnostic components for quantitative assessment of an analyte, and at least one of the top panel or the bottom panel comprises a plurality of image registration markers included on the top panel and a plurality of image calibration markers.
    Type: Application
    Filed: March 6, 2024
    Publication date: September 12, 2024
    Inventors: Brianna Wronko, Samuel Parks, Nidhi Menon, Brittany Auyoung, Prava Sharma, Rohan Vemu, David Beery
  • Publication number: 20240299944
    Abstract: In accordance with embodiments herein a method for capturing cells of interest in a digital microfluidic system is provided, comprising utilizing a droplet actuator to transport a sample droplet to a microwell device. The microwell device includes a substrate having a plurality of microwells that open onto a droplet operations surface of the microwell device. The sample droplet includes cells of interest that enter the microwells. The method introduces capture beads to the microwells, and the capture elements are immobilized on the capture beads. The method utilizes the droplet actuator to transport a cell lysis reagent droplet to the microwell device. Portions of the cell lysis reagent droplet enter the microwells and, during an incubation period, cause the cells of interest to release analyte that is captured by the capture elements on the capture beads.
    Type: Application
    Filed: May 14, 2024
    Publication date: September 12, 2024
    Inventors: Arash Jamshidi, Yan-you Lin, Farnaz Absalan, Sarah Stuart, Gordon Cann, Yir-Shyuan Wu, Tarun Khurana, Jeffrey S Fisher
  • Publication number: 20240299945
    Abstract: Embodiments relate to devices, systems, methods and compositions useful for routing and tracking multiple mobile units within a microfluidic device having an inlet channel connected to a multi-way sorting junction, which is fluidly connected with a plurality of 4 or more channels, and a steering mechanism for directing the flow of the mobile units according to a predetermined algorithm. Mobile units can be routed and followed through the microfluidic device in an ordered flow, such that the mobile units are exposed to chemical environments and/or enzymatic synthesis reactions associated with the channels. Mobile units can be steered in multiple directions, between the sorting junctions and the channels by the steering mechanism by changes in flow or pressure. Some such devices, systems, methods and compositions include mobile units that can flow in both the forward and reverse directions and into each of as plurality of 4 or more channels from two sorting junctions.
    Type: Application
    Filed: September 3, 2022
    Publication date: September 12, 2024
    Inventors: Matthew Hill, Marc Unger, Ashraf Wahba, Ouriel E. Caen
  • Publication number: 20240299946
    Abstract: An analyzer control product provided with a sealed rack tube containing a preconfigured volume of analyzer control fluid is described. In particular, the rack tube is provided with a base portion; a top portion; and a sidewall extending from the base portion to the top portion, the sidewall having an inner peripheral surface and an outer peripheral surface, at least one of the inner peripheral surface and the outer peripheral surface in contact with the base portion to form a control fluid void. The analyzer control fluid is within the control fluid void. The analyzer control fluid has a preconfigured volume. A sealing member is attached to the top portion to seal the control void.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 12, 2024
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Lloyd Schulman
  • Publication number: 20240299947
    Abstract: The disclosure relates to novel components of a gyratory crusher (1) which aim to promote self-alignment of a mainshaft assembly (2) upon introduction of the mainshaft assembly (2) into the gyratory crusher (1) by lowering the mainshaft assembly (2) from above the gyratory crusher (1) into the gyratory crusher (1). The novel components may include a dust bonnet (9) having a plurality of guides (15), an end plate (32) having a lower alignment chamfer (36), and/or a counterweight (13) having an alignment chamfer (41). Each of the novel components may be configured to bias a lower mainshaft (26) of the mainshaft assembly (2) of the gyratory crusher (1) into concentric alignment with a bore (56) of the eccentric (11) or eccentric liner (12).
    Type: Application
    Filed: December 18, 2023
    Publication date: September 12, 2024
    Inventors: William George Malone, Stephen Richard Harris
  • Publication number: 20240299948
    Abstract: A drum assembly for a ball mill system may comprise: a drum having a first flange extending axially forward from a first radial wall, a second flange extending axially aft from a second radial wall, and a cylinder shell extending axially from a first radially outer end of the first radial wall to a second radially outer end of the second radial wall; a frame coupled to the first flange; and an inlet liner coupled to the frame, the inlet liner comprising a plurality of inlet segments disposed circumferentially adjacent to each other, the inlet liner defining an inlet radius for the drum assembly.
    Type: Application
    Filed: May 14, 2024
    Publication date: September 12, 2024
    Applicant: FREEPORT MINERALS CORPORATION
    Inventor: Dale Coray
  • Publication number: 20240299949
    Abstract: A tool-integrated medical waste sterilization processing barrel includes a treatment barrel, a discharge port set at a bottom edge of the treatment barrel, and an integrated cutting tool is provided at the bottom of the treatment barrel; the integrated cutting tool includes a mounting block in a shape of truncated square pyramid, the mounting block has a cutter on each bevel, the cutter is in a plane parallel to the corresponding bevel of the mounting block, the mounting block has a power chamber with a downward opening, the power chamber has a power member, the input end of the cutter extends into the power chamber and is connected to the output end of the power member, and a rotating member is connected between the mounting block and the treatment barrel.
    Type: Application
    Filed: May 21, 2024
    Publication date: September 12, 2024
    Applicant: ZHEJIANG WEIDUN ENVIRONMENTAL TECHNOLOGY CO., LTD.
    Inventors: Yiming CHEN, Weixing CHEN, Junfeng LIU, Guanzhong HUANG
  • Publication number: 20240299950
    Abstract: A high crushing efficiency medical waste treatment machine includes a crushing cylinder, a crushing knife set provided at the bottom of the crushing cylinder, an intermittent material discharge mechanism set on one side of the crushing knife set, a pressurizing mechanism slidingly set along the axis of the crushing cylinder on the other side of the crushing knife set. The pressurizing mechanism includes a mounting frame slidingly connected to the inner wall of the crushing cylinder, the mounting frame rotatably connected to a material tumbling plate made of magnetic material; when the intermittent material discharging mechanism discharges material, the pressurizing mechanism moving in a direction close to the crushing knife set; when the intermittent material discharges mechanism stops discharging material, the material tumbling plate rotates.
    Type: Application
    Filed: May 21, 2024
    Publication date: September 12, 2024
    Applicant: ZHEJIANG WEIDUN ENVIRONMENTAL TECHNOLOGY CO., LTD.
    Inventors: Yiming CHEN, Weixing CHEN, Junfeng LIU, Guanzhong HUANG
  • Publication number: 20240299951
    Abstract: A mobile cone plant with canted run-on jacks for limited vibration of the chassis without a need for clamping or extremely tight tolerances in telescopic jack parts.
    Type: Application
    Filed: March 18, 2024
    Publication date: September 12, 2024
    Inventors: Rex Mikle CARTER, Edwin J. SAUSER, Alexander Evan ROSS
  • Publication number: 20240299952
    Abstract: The options for the modular concentration bowl of the centrifugal concentrator and the options for the method of its manufacture relate to devices designed for mineral dressing, and can be used to separate solid particles by density. As an example, the claimed invention can be used for processing auriferous ores and finely dispersed sands as well as copper and nickel ores that are not amenable to magnetic separation. The objective of the claimed invention is to create a device for gravitational separation of ores with a long service lifetime and convenient in service as well as to develop a method for its manufacture. The technical result of the claimed invention with respect to the device and method is an increase in the service lifetime of the concentration bowl, its maintainability, reliability of the device and ease of manufacture.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 12, 2024
    Inventor: Yury Anatolevich SHELKUNOV
  • Publication number: 20240299953
    Abstract: Dynamic bale creation is disclosed, including: a plurality of sorting facility devices configured to capture objects from a material stream based at least in part on target sorting metrics specified by a bale recipe; and one or more processors configured to: determine current sorting metrics associated with captured objects that are to be added to a collection mechanism at a sorting facility; and determine whether to trigger reconfiguration of at least a subset of the plurality of sorting facility devices based at least in part on a comparison between the target sorting metrics and the current sorting metrics.
    Type: Application
    Filed: March 7, 2024
    Publication date: September 12, 2024
    Inventors: Jacob Fitzgerald, Jason M. Calaiaro, Carter J. Schultz, Cameron D. Douglas, Matthew J. Koos, Carson C. Potter, Amanda M. Marrs, Matanya B. Horowitz
  • Publication number: 20240299954
    Abstract: A negative ionization cell for negatively ionizing fine, ultrafine or nanoparticles present in an air flow defined by fumes, vehicle exhaust gases or indoor environments is disclosed. The cell has a body defining an ionizing part having first and second portions which are elongated, preferably plate-like, and facing each other. The first portion has a negative voltage to generate a potential difference with the second portion. The first and second portions also define a passage for the air flow and the first portion supports a plurality of elongated and sharp-pointed bodies projecting into the passage for the air flow and orthogonally to the air flow. The elongated and sharp-pointed bodies generate an electron flow, directed toward the second portion due to the potential difference and intercept the solid particles in the air flow to negatively charge them. An air purifier including the negative ionization cell is also disclosed.
    Type: Application
    Filed: March 14, 2022
    Publication date: September 12, 2024
    Inventor: Salvatore VANELLA
  • Publication number: 20240299955
    Abstract: Disclosed are a method and a device for temperature control of a centrifuge, a centrifuge and a storage medium. The method for temperature control of a centrifuge includes: acquiring a current temperature of the centrifugal chamber; in a case where a difference between the current temperature and a set temperature is less than or equal to a difference threshold value, according to the set temperature and a set rotational speed of the rotor, determining a target input parameter for temperature adjustment; and inputting the target input parameter, the current temperature and the set temperature into the PID controller.
    Type: Application
    Filed: May 31, 2022
    Publication date: September 12, 2024
    Applicants: QINGDAO HAIER BIOMEDICAL TECHNOLOGY CO., LTD., QINGDAO HAIER BIOMEDICAL CO., LTD.
    Inventors: Zepeng DUAN, Huanwen JU, Panfei WANG, Huan CHEN, Wei HU, Dongchen YU, Menglong YIN
  • Publication number: 20240299956
    Abstract: A hand vacuum cleaner has a cyclone assembly comprising a cyclone and a dirt collection chamber. The cyclone assembly has a cyclone assembly axis extending centrally between a front end of the cyclone assembly and a rear end of the cyclone assembly. The cyclone has a horizontally extending cyclone axis and the dirt collection chamber has a lower end which is at a lower elevation than a lower end of the cyclone chamber. A line that extends in a common direction with the cyclone assembly axis intersects the dirt collection chamber at an elevation below the cyclone chamber, a pre-motor filter and a handle of the hand vacuum cleaner.
    Type: Application
    Filed: May 17, 2024
    Publication date: September 12, 2024
    Inventor: Wayne Ernest Conrad
  • Publication number: 20240299957
    Abstract: The present inventive concept relates to a substrate treatment apparatus comprising: a chamber; a substrate support portion which supports at least one substrate in the chamber; a first spray portion which sprays a first gas toward the substrate support portion from the upper side of the substrate support portion; a second spray portion which sprays a second gas toward the substrate support portion from the upper side of the first spray portion; and a buffer portion formed between the first spray portion and the second spray portion, wherein the first spray portion includes a plurality of first spray holes and the second spray portion includes a first supply hole which supplies the first gas to the buffer portion and a second spray hole which passes through the buffer portion. The center of an injection port and the center of a discharge port of the first supply hole are spaced apart from each other in the vertical direction, and the discharge port is formed toward a space among the first spray holes.
    Type: Application
    Filed: January 10, 2022
    Publication date: September 12, 2024
    Inventors: Ji Hun LEE, Ji Won LEE