Patents Issued in October 24, 2024
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Publication number: 20240351935Abstract: Disclosed herein is a glass that exhibits high hardness and crack-resistance and can potentially be synthesized using conventional glass manufacturing infrastructure. The glass has high hardness and crack resistance than other commercial glasses. Apart from that, the glass exhibits good glass forming ability and high chemical durability.Type: ApplicationFiled: July 3, 2024Publication date: October 24, 2024Applicant: Rutgers, The State University of New JerseyInventors: Ashutosh Goel, Anjali Yadav
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Publication number: 20240351936Abstract: Provided is a chemically strengthened optical glass having an improved impact resistance and a high hardness while maintaining the refractive index, the Abbe number and the transmittance required in the conventional optical glasses. The chemically strengthened optical glass has a compressive stress layer on the surface thereof, contains, in mass % in terms of oxide, 20.0-50.0% of an SiO2 component, 10.0-45.0% of a TiO2 component and 0.1-20.0% of an Na2O component, has a refractive index (nd) of 1.65-1.85, and is characterized by having an impact resistance of 8 cm or more in a sandpaper falling ball test in which a 16.0 g SUS ball is dropped thereon.Type: ApplicationFiled: July 12, 2022Publication date: October 24, 2024Inventors: SAYA KIKKAWA, KEISUKE SHIMAMURA
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Publication number: 20240351937Abstract: Method for manufacturing slab articles from a mix, comprising the steps of a) preparing a mix comprising a preponderant amount of a glass frit and a binder, b) distributing the mix in a support, c) compacting the mix, d) drying the mix, e) sintering the mix and f) cooling the article. The glass frit comprises a weight amount of silica (SiO2) comprised between 62% and 68%, a weight amount of alumina (Al2O3) comprised between 3% and 5%, a weight amount of potassium oxide (K2O) comprised between 3% and 5%, a weight amount of calcium oxide (CaO) comprised between 18% and 26% and a weight amount of magnesium oxide (MgO) comprised between 1% and 4% The cooling step is performed in a controlled manner by modulating the cooling speed in a temperature range not greater than 1.160° C. and not less than 1.000° C. in order to perform the at least partial devitrification and crystallization of the glass frit. The invention also relates to a glass frit and an article in slab form.Type: ApplicationFiled: July 1, 2024Publication date: October 24, 2024Inventor: Luca Toncelli
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Publication number: 20240351938Abstract: Provided is a water-repellent glass member having excellent water repellency even without forming a water-repellent film on its surface. A water-repellent glass member 1 has a surface 1a with unevenness, wherein when a cutoff value of a high-pass filter ?c in a 5 ?m×5 ?m area of the surface 1a with unevenness is 2.5 ?m, a mean width RSm1 of roughness profile elements is not less than 70 nm and not more than 800 nm, and when a cutoff value of a low-pass filter ?s in a 140 ?m×105 ?m area of the surface 1a with unevenness is 0.80 ?m, a mean width RSm2 of roughness profile elements is not less than 3.0 ?m and not more than 100.0 ?m.Type: ApplicationFiled: August 19, 2022Publication date: October 24, 2024Inventors: Takumi KINOSHITA, Naoki FUJITA
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Publication number: 20240351939Abstract: Provided is a substrate for mounting an LED that can be applied to a thin base material and can result in a sufficient reflectance, particularly a substrate for mounting an LED, adaptable to a mini-LED and a ?-LED. In the substrate for mounting an LED, including a base material and a reflective layer that is layered on an upper region thereof, plural openings are disposed at generally equal spacings in longitudinal and lateral directions in the reflective layer, respectively, the reflective layer is the cured product of a curable resin composition including a curable resin and titanium oxide, the cured product has a storage elastic modulus of 4.0 GPa or less at 25° C., the spacings between the opening and the opening adjacent thereto in the longitudinal direction and the lateral direction are not less than twice the lengths of the opening in the longitudinal direction and the lateral direction, respectively, and the total area rate of the openings with respect to the area of the reflective layer is 0.Type: ApplicationFiled: July 26, 2022Publication date: October 24, 2024Inventors: Meiten KOH, Haruka ONODA, Masayuki SHIMURA, Kosuke NAKAJIMA
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Publication number: 20240351940Abstract: A polymer brush includes a substrate material, a polymerization initiator layer containing a hydrolysis and condensation polymerization polymer comprising a first organosilane and a metal alkoxide on a surface of said substrate material, and polymer chains extending from a surface of the polymerization initiator layer. The first organosilane is a polymerization initiator group-containing organosilane having the following formula (I): X—R1-Ph-(R2)m—Si—R3nR43-n . . . (I) where X stands for a halogen atom, R1 stands for an alkylene group having 1 to 3 carbon atoms, Ph stands for a phenylene group, R2 stands for a C1 to C10 alkylene group optionally via an oxygen atom, R3 stands for an alkoxy group having 1 to 3 carbon atoms or chloro group, R4 stands for an alkyl group having 1 to 6 carbon atoms, m is 0 or 1, n is 1, 2 or 3.Type: ApplicationFiled: July 1, 2024Publication date: October 24, 2024Inventors: Tomoya SATO, Chihiro URATA, Atsushi HOZUMI
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Publication number: 20240351941Abstract: The presently described subject matter relates to an atmospheric chemical vapor deposition process for depositing a hafnium-containing coating on a glass substrate by reacting a precursor gas mixture containing an organohafnium compound, molecular oxygen, and an olefinic hydrocarbon. Glass articles having a hafnium-containing layer formed on the glass substrate are also provided.Type: ApplicationFiled: August 25, 2022Publication date: October 24, 2024Applicant: Pilkington Group LimitedInventors: Srikanth VARANASI, Michael REMINGTON
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Publication number: 20240351942Abstract: A greenhouse glazing, including a glass substrate with a first surface containing a first coating and a second surface containing a second coating. The first surface is an air-side face of the glass substrate and the second surface is a tin-side face of the glass substrate, and the second surface is textured prior to a deposition of the second coating in such a way that a roughness parameter Rsm is at most 155 ?m. The first coating on the first surface contains a nano-porous silica layer having a thickness between 80 and 150 nm and a transparent conductive oxide located between the nano-porous silica layer and the first surface of the glass substrate. The second coating on the second surface contains a nano-porous silica layer having a thickness between 80 and 180 nm.Type: ApplicationFiled: August 30, 2022Publication date: October 24, 2024Applicant: AGC GLASS EUROPEInventors: Seyedmohammad SHAYESTEHAMINZADEH, Daphné STASSEN, Fabrice DUFOUR
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Publication number: 20240351943Abstract: Provided is a method of producing a plating deposit which enables the production of a plating deposit with good adhesion to a glass substrate. Included is a method of producing a plating deposit, which includes: (1) forming a metal oxide layer on a surface of a glass substrate; (2) performing a first heat treatment after the step (1); (3) forming an electroless copper plating deposit on the metal oxide layer after the step (2); (4) performing a second heat treatment after the step (3); and (5) forming an electrolytic copper plating deposit on the electroless copper plating deposit after the step (4).Type: ApplicationFiled: April 15, 2024Publication date: October 24, 2024Applicant: C.Uyemura & Co., Ltd.Inventors: Takuya Komeda, Hisamitsu Yamamoto, Tetsuji Ishida
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Publication number: 20240351944Abstract: A coated article includes a substrate and a functional coating applied over at least a portion of the substrate, the functional coating including: a first layer over the substrate; a seed layer over the first layer, the seed layer selected from the group consisting of titanium, titanium aluminum, niobium, titanium niobium, stainless steel, mixtures thereof, alloys thereof, and combinations thereof; a metallic layer over the seed layer; a primer layer over the metallic layer, the primer layer selected from the group consisting of titanium, titanium aluminum, niobium, titanium niobium, nickel chromium, stainless steel, mixtures thereof, alloys thereof, and combinations thereof; and a second layer over the primer layer. A method of making the coated article, a method of reducing haze in a coated article, a method of protecting a metallic layer in a coated article, an insulating glass unit, and a windshield are also provided.Type: ApplicationFiled: April 16, 2024Publication date: October 24, 2024Inventors: Maryanne Griffin, Jessica Smith
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Publication number: 20240351945Abstract: A method of forming a glass ceramic substrate having a through-glass via can include treating at least a portion of a first major surface of a precursor glass substrate along a laser scan path with a source of laser energy to form a treated precursor glass substrate. The through-glass via has a predetermined shape and extends through the first major surface of the glass ceramic substrate and a second major surface of the glass ceramic substrate. The first major surface defines a first opening and the second major surface defining a second opening and a ratio of a waist diameter of the through-glass via, measured at a location between the first opening and the second opening, to a surface diameter of the through-glass via, measured at either the first opening of the second opening of the through-glass via is in a range of from about 30% to about 100%.Type: ApplicationFiled: August 23, 2022Publication date: October 24, 2024Inventors: Daniel Wayne Levesque, JR., Lina Ma, Heather Nicole Vanselous, Jingshi Wu
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Publication number: 20240351946Abstract: The present invention relates to a binder composition comprising Portland cement clinker, calcium sulfate, an inorganic sulfate source having a solubility higher than 100 g/l at 20° C. polyalcohol and/or metal salts thereof, a carbonate selected of the group consisting of organic carbonate, alkali carbonate, and mixtures thereof, a component F), and dispersant having a charge density of more than 0.80 ?eq/g.Type: ApplicationFiled: August 9, 2022Publication date: October 24, 2024Inventors: Harald GRASSL, Joachim DENGLER, Roswitha MUSSNER, Zsolt SZENTMIKLOSI
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Publication number: 20240351947Abstract: A method for producing a supplementary cementitious material from concrete waste and similar materials includes the steps of i) providing a starting material comprising hydrated cement and aggregate comprising silicate and/or alumino-silicate, ii) hydrothermal treatment of the starting material provided in step i) to obtain a hydrothermally activated material, and iii) carbonation of the hydrothermally activated material of step ii) to provide the supplementary cementitious material, as well as supplementary cementitious material obtainable by the method, hydraulic binder comprising the supplementary cementitious material and use of the supplementary cementitious material and of the hydraulic binder for making hydraulic building materials.Type: ApplicationFiled: May 4, 2022Publication date: October 24, 2024Applicant: HConnect 2 GmbHInventors: Maciej ZAJAC, Jan SKOCEK, Frank BULLERJAHN, Gerd BOLTE
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Publication number: 20240351948Abstract: The invention comprises a product. The product comprises a carbonation aid or a microporous material or a combination thereof and a carbonatable mineral containing one or more of un-carbonated Ca, Mg, Na, K, Fe, wherein the carbonation aid facilitates the conversion of one or more of CaO, MgO, Na2O, K2O or FeO to a carbonate or a CO3 containing mineral in the presence of CO2, wherein the carbonatable mineral has a volume-based mean particle size of less than or equal to 100 ?m and wherein one or more of the carbonation aid or a microporous material or a combination thereof or the carbonatable mineral has carbon dioxide bound thereto at a concentration greater than its atmospheric concentration.Type: ApplicationFiled: April 23, 2024Publication date: October 24, 2024Applicant: Greencraft LLCInventor: Romeo Ilarian Ciuperca
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Publication number: 20240351949Abstract: A cement-containing composition includes a proportion of 0.05% by weight to 1% by weight, based on the cement content, of an organosilicon compound(S). The organosilicon compound contains at least 70% by weight of units of the formula (1), R1R2 (OR3)xSiO(2-x)/2 (1). In formula 1, R1 is a methyl group, R2, in all units of the formula (1), may be identical or different and is a monovalent, SiC-bonded, aliphatic hydrocarbon radical having 4 to 22 carbon atoms, R3, in all units of the formula (1), may be identical or different and is a hydrogen atom or an alkyl radical having 1 to 4 carbon atoms, and x is 0 or 1.Type: ApplicationFiled: July 7, 2021Publication date: October 24, 2024Applicant: Wacker Chemie AGInventors: Wei Cai, Dominik JANTKE, Peter JERSCHOW, Volker STANJEK
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Publication number: 20240351950Abstract: A composite composition for forming a composite which can be used for potting electronics and/or electrics, in particular power electronics. To form a composite which is solid, in particular rigid, adhesive, in particular self-adhesive, thermally stable, and has a low coefficient of thermal expansion, high thermal conductivity and thermal diffusivity, and high thermal endurance, and protects and compressively stabilizes electronics and/or electrics and increases their lifespan and/or performance, the composite composition includes, relative to the total weight of the composite composition, ?10 wt. % to ?95 wt. % of at least one filler, and ?1 wt. % to ?15 wt. % of at least one silanol. A method for preparing a silanol composition; a corresponding silanol composition; a method for preparing the composite composition; a method for preparing a composite and/or a solid structure; a composite and/or a solid structure; and the use thereof, are also described.Type: ApplicationFiled: September 27, 2022Publication date: October 24, 2024Inventors: Stefan Henneck, Tobias Kohler
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Publication number: 20240351951Abstract: The present disclosure relates to concrete compositions including calcium aluminate cement, Portland cement, gypsum, and slag, to mortar mixtures including such compositions, to methods for lining a concrete surface with such mixtures, and to liners formed thereby.Type: ApplicationFiled: October 5, 2023Publication date: October 24, 2024Inventor: Ali Mahdi Al-Yami
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Publication number: 20240351952Abstract: The invention relates to a process for the preparation of a zirconia granulate from a zirconia powder and to the use of the granulate for the preparation of dental blanks and dental restorations.Type: ApplicationFiled: August 9, 2022Publication date: October 24, 2024Inventors: Alexander ENGELS, Bettina SCHWENDINGER
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Publication number: 20240351953Abstract: A process for post-treatment of electroceramic composite material is disclosed. The process comprises introducing electroceramic composite material and flow-able organometallic compound to a pressure chamber, and degassing (1) the electroceramic composite material by creating a vacuum or underpressure in the pressure chamber, while the electroceramic composite material is immersed (2) in said organometallic compound. Then the pressure is elevated to an atmospheric pressure, wherein said flowable organometallic compound is absorbed (3) into at least part of the pores of the composite material. The electroceramic composite material containing said organometallic compound absorbed into said pores, is then treated (4) with water, water vapour and/or other chemical, thereby producing metal oxide impregnated electroceramic material containing solid metal oxide absorbed into said pores. Instead of flowable organometallic compound, a suspension of metal or metal oxide nanoparticles may be used for the post-treatment.Type: ApplicationFiled: August 31, 2022Publication date: October 24, 2024Inventors: Yang BAI, Heli JANTUNEN, Jari JUUTI, Mikko NELO
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Publication number: 20240351954Abstract: A carbon-negative Engineering Structural Material (ESM) has a compressive strength approaching that of concrete and relies on a carbon-absorbing enzyme for crystalline formations formed cooperatively with a porous structure to achieve load-bearing properties. A tough scaffold forms through capillary suspension, a technique that utilizes capillary forces to concentrate particles in a liquid matrix. Carbonic anhydrase, a zinc-containing enzyme extracted from bovine erythrocytes, is harnessed to grow mineral materials, and the capillary suspension is used to create a construction material, including sand and a polymer. This combination enables the incorporation of precipitated calcium minerals into the structure, resulting in the development of water-resistant and load-bearing construction materials.Type: ApplicationFiled: April 18, 2024Publication date: October 24, 2024Inventors: Nima Rahbar, Shuai Wang, Suzanne Scarlata
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Publication number: 20240351955Abstract: Disclosed are methods of forming a dielectric material. One method comprises modifying a tungsten bronze crystal structure by substituting one or more lattice sites with one or more elements selected to increase a quality factor (Q) of the dielectric material.Type: ApplicationFiled: February 23, 2024Publication date: October 24, 2024Inventor: Michael David Hill
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Publication number: 20240351956Abstract: A set control composition for cementitious systems comprises a) (a-1) a hydroxy monocarboxylic acid or a salt thereof, and (a-2) optionally, a polycarboxylic acid having a carboxylic acid equivalent weight of 333 or less, or a salt thereof, the carboxylic acid equivalent weight being the molecular weight of the polycarboxylic acid divided by the number of carboxylic acid functional groups, wherein (a-1) contributes at least 90% of the carboxyl groups to the total number of carboxyl groups of (a-1) and (a-2), b) at least one of (b-1) a borate source, and (b-2) a carbonate source, wherein the carbonate source is selected from inorganic carbonates having an aqueous solubility of 0.1 g·L?1 or more at 25° C., and organic carbonates, in a weight ratio of b) to a) in the range of 1.2 to 20, and c) a polyol in a weight ratio of c) to a) in the range of 1.0 to 10.Type: ApplicationFiled: September 28, 2022Publication date: October 24, 2024Inventors: Bernhard SACHSENHAUSER, Massimo BANDIERA, Sabine HIMMELEIN, Kai Steffen WELDERT, Peter SCHWESIG, Matthias KLEIN, Ramzi FARRA, Klaus LORENZ
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Publication number: 20240351957Abstract: An admixture for mineral binder compositions, especially for concrete, the admixture includes at least one kinetic regulator selected from esters of hydroxy carboxylic acid, especially citric acid esters, tartaric acid esters, lactic acid esters, gluconic acid esters, malic acid esters, glycolic acid esters, and/or mandelic acid esters, optionally an accelerator for the hydration of cement, and optionally water. Admixtures reduce the maximum heat flow from mineral binder composition, especially concrete, without unduly retarding setting and/or curing thereof.Type: ApplicationFiled: August 31, 2022Publication date: October 24, 2024Applicant: SIKA TECHNOLOGY AGInventors: Arnd EBERHARDT, Thomas MÜLLER, Johannes UNSELD, Lukas FRUNZ, Emmanuel GALLUCCI, Patrick JUILLAND, Denise SCHÖNENBERGER, Luis PEGADO
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Publication number: 20240351958Abstract: An article includes a substrate. The substrate includes at least two phases. The first phase includes a carbon-carbon (C/C) composite. The second phase includes a metal carbide. The second phase is disposed within a plurality of interconnected pores of the first phase, wherein the second phase extends from a surface of the substrate to a depth of at least 300 micrometers below the surface of the substrate.Type: ApplicationFiled: April 18, 2023Publication date: October 24, 2024Inventors: Mehrad Mehr, Bahram Jadidian
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Publication number: 20240351959Abstract: The present invention relates to the use of novel nitrification inhibitors of formula I, which are ethynylpyridine compounds. Moreover, the invention relates to the use of compounds of formula (I), Formula (I) as nitrification inhibitors, i.e. for reducing nitrification, as well as agrochemical mixtures and compositions comprising the nitrification inhibitors of formula (I).Type: ApplicationFiled: May 20, 2022Publication date: October 24, 2024Inventors: Barbara Nave, Alexander Wissemeier, Peter Nesvadba, Joachim Dickhaut, Klaus Daeschner
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Publication number: 20240351960Abstract: A method for producing phosphoryl triamide OP(NH2)3 or thiophosphoryl triamide SP(NH2)3, in which: a) phosphoryl trichloride OPCl3 or thiophosphoryl trichloride SPCl3, respectively, is reacted with gaseous ammonia in an apolar liquid phase to give a first precipitate comprising, respectively, phosphoryl triamide or thiophosphoryl triamide, and ammonium chloride, and b) the first precipitate is treated with sodium carbonate or potassium carbonate, in a polar organic liquid phase, to give a second precipitate comprising NaCl and the phosphoryl triamide or thiophosphoryl triamide remaining in said polar organic liquid phase, and the second precipitate is separated from the polar organic liquid phase, the latter possibly undergoing a further concentration step to enrich it in phosphoryl triamide or thiophosphoryl triamide.Type: ApplicationFiled: April 27, 2022Publication date: October 24, 2024Inventors: Bernard BEAL, Eric BELLEPERCHE, Bruno MONTAGNIER
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Publication number: 20240351961Abstract: A multi-purpose putty product usable as a lamp fuel, first aid medication, water proofing agent, water sealant, and UV responsive marker is shown and described. The putty component may include waxes, oils, pine gum rosin, powdered metallic thermite fuel, and cotton fibers. Optionally, the putty may include a colorant and plant essential oil as an odorant. The putty may be provided in kit form, with a receptacle and closure, and a tool enabling putty product in the receptacle to be exposed and held erect for service as a wick while burning.Type: ApplicationFiled: July 2, 2024Publication date: October 24, 2024Inventors: William Charles Bartlett, Cheston Davis
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Publication number: 20240351962Abstract: A method for converting lower alkanes to higher liquid products, comprising reacting one or more C2 to C12 alkanes with a bifunctional catalyst comprising platinum (Pt) or palladium (Pd) and at least one other metal (M) to provide an alloy (Pt-M or Pd-M) containing at least 0.1 wt % of the platinum (Pt) or palladium (Pd), based on a total weight of the catalyst; a silica or alumina support; and an acidic zeolite, at a temperature of about 350° C. to 700° C. to provide a liquid product having a boiling point of 38° C. to 205° C.Type: ApplicationFiled: May 23, 2022Publication date: October 24, 2024Inventors: Jeffrey Miller, Che-Wei Chang
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Publication number: 20240351963Abstract: Systems and processes for the production of a high purity isobutylene stream, a high purity isooctene stream or for the co-production of a high purity isobutylene and a high purity isooctene. The systems and processes advantageously process mixed C4 hydrocarbon streams via etherification, back cracking, isomerization, and/or dimerization, along with various separation systems, to produce the desired high purity streams.Type: ApplicationFiled: April 17, 2024Publication date: October 24, 2024Applicant: LUMMUS TECHNOLOGY LLCInventor: Rosette Barias
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Publication number: 20240351964Abstract: A process for producing isopentane and isoamylene can comprise passing a feed stream comprising C5 hydrocarbons through a hydrodesulfurization assembly to produce a first stream: passing the first stream to a first separation assembly to produce a second stream and a first separated stream: passing the second stream to a deisopentanizer assembly to produce a second separated stream comprising isopentane, a third separated stream comprising C6+ hydrocarbons, and a raffinate stream comprising C5 hydrocarbons; and passing the raffinate stream to a reactor assembly to produce a reaction product stream comprising isoamylene. The present disclosure also provides for a system for producing isopentane and isoamylene.Type: ApplicationFiled: September 12, 2022Publication date: October 24, 2024Inventors: Shehzada Khurram, Ernesto Uehara, Chandrasekar Subramani, Rathinam Jothi Mahalingam
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Publication number: 20240351965Abstract: Disclosed are 4-hydroxylphenyl substituted carbocycles and there use as selective agonists of the estrogen receptor beta isoform (ER?). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ER activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders.Type: ApplicationFiled: August 23, 2022Publication date: October 24, 2024Inventors: William A. Donaldson, Daniel S. Sem, Edward A. Wetzel
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Publication number: 20240351966Abstract: Provided are a class of alkylphenol compounds and a preparation method therefor. Specifically provided are a new alkyl polyphenol compound as represented by chemical formula I, and a preparation method therefor and the use thereof in the treatment of metabolic syndrome.Type: ApplicationFiled: May 11, 2022Publication date: October 24, 2024Inventors: Fajun NAN, Jingya LI, Zheng ZHANG, Yanan DUAN, Yangming ZHANG, Dandan CHEN, Chengqiu DAI
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Publication number: 20240351967Abstract: Disclosed are methods for preparing zingerone from ginger using alkaline solutions, as well as compositions obtained using these methods, and methods for using these compositions. Specifically disclosed are pharmaceutical compositions, and treatment methods employing zingerone in combination with other therapeutics such as gentamicin, vancomycin, and cefotaxime.Type: ApplicationFiled: August 11, 2022Publication date: October 24, 2024Applicant: Evithe LimitedInventor: Cynthia HUNEFELD-GAIKEMA
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Publication number: 20240351968Abstract: This disclosure relates to a process which involves reacting 2-butanone with acetaldehyde in the presence of a zinc complex catalyst in a reaction zone to produce a product mixture comprising 4-hexen-3-one and 3-methyl-3-penten-2-one. This disclosure also relates to a process which involves (a) reacting 2-butanone with acetaldehyde in the presence of a zinc complex catalyst to produce a product mixture comprising 4-hexen-3-one, 3-methyl-3-penten-2-one and the zinc complex catalyst; (b) recovering the zinc complex catalyst from the product mixture; and (c) reusing the recovered zinc complex catalyst in the reacting step (a).Type: ApplicationFiled: March 18, 2022Publication date: October 24, 2024Inventor: Hongping XU
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Publication number: 20240351969Abstract: A method for preparing methyl isobutyl ketone comprises reacting mesityl oxide and methyl isobutyl alcohol under the action of a copper-based catalyst to produce methyl isobutyl ketone, where mesityl oxide and methyl isobutyl alcohol are employed to carry out hydrogen in-situ transfer under the action of the copper-based catalyst, and methyl isobutyl ketone is prepared in one step. The entire reaction process does not require an external hydrogen system. The reaction is carried out under normal pressure, and the process flow is short. The reaction has high atom utilization, high safety, and is suitable for popularization and industrial application.Type: ApplicationFiled: July 2, 2024Publication date: October 24, 2024Inventors: Zhengan MIAO, Shiwu LI, Yingjie XIANG
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Publication number: 20240351970Abstract: The invention relates to a preparation method and application of 5-bromo-2-chloro-benzoic acid as a synthetic raw material of a hypoglycemic agent. Specifically, the 5-bromo-2-chloro-benzoic acid is prepared by taking a 5-bromo-2-aminobenzoic acid derivative as an initial raw material through two steps of reactions of diazotization, chlorination and hydrolysis, and the obtained product has the advantages of few isomer impurities, high reaction yield, good purity, low cost and suitability for industrial production. The invention also relates to the application of the 5-bromo-2-amino-benzoic acid in preparing antidiabetic drugs.Type: ApplicationFiled: December 24, 2021Publication date: October 24, 2024Inventors: Yunfeng LI, Zhiguo ZHENG
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Publication number: 20240351971Abstract: The present invention relates to a method for extracting ferulic acid and/or its salts, comprising a step (a) in which a biomass is extruded in the presence of a base. The present invention also relates to ferulic acid in protonated or salified form that can be obtained according to the method of the present invention. Finally, the present invention also relates to a method for preparing vanillin from ferulic acid obtained according to the method of the present invention. The invention can be used in particular in the field of food, cosmetics and flavours.Type: ApplicationFiled: July 22, 2022Publication date: October 24, 2024Applicant: SPECIALTY OPERATIONS FRANCEInventor: Rodolphe Sapey-Triomphe
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Publication number: 20240351972Abstract: A process for performing a heterogeneously catalysed reaction for the oxidative esterification of aldehydes to carboxylic esters can be performed. Against this background, the process has made it possible to keep the heterogeneous, precious metal catalyst used in this method active during operation in a particularly effective manner, in order to lengthen the period between downtimes and to effect particularly sustainable catalyst management. This gives rise to the possibility of performing such processes in a very simple, economically viable and environmentally benign manner.Type: ApplicationFiled: August 19, 2022Publication date: October 24, 2024Applicant: Röhm GmbHInventors: Andreas Rühling, Steffen Krill, Florian Zschunke, Belaid Ait Aissa, Andreas Tepperis, Mounir Stitou
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Publication number: 20240351973Abstract: The present invention relates to a process for purifying a crude diester monomer feedstock comprising: a) a step of mixing the crude diester monomer feedstock with an aqueous solvent, at a temperature of between 60° C. and 150° C., in order to obtain a diester monomer aqueous mixture, the amount of aqueous solvent introduced being adjusted so that the crude diester monomer feedstock represents between 20% and 90% of the total weight of the diester monomer aqueous mixture; b) a step of adsorbing the diester monomer aqueous mixture, at a temperature of between 60° C. and 150° C. and a pressure of between 0.1 and 1.0 MPa, in order to obtain a purified monomer effluent.Type: ApplicationFiled: June 7, 2022Publication date: October 24, 2024Applicants: IFP ENERGIES NOUVELLES, JEPLAN, INC.Inventors: David CHICHE, Guillaume BLANCKE, Damien LEINEKUGEL LE COCQ
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Publication number: 20240351974Abstract: The invention relates to lipid compounds that can be used alone or in combination with other lipid components, such as neutral lipids, charged lipids, steroids, and polymer conjugated lipids to form lipid nanoparticles for delivery of therapeutic and/or prophylactic agents; pharmaceutical compositions containing the lipid nanoparticles; and methods of using the lipid nanoparticles to treat or prevent diseases.Type: ApplicationFiled: March 31, 2022Publication date: October 24, 2024Inventors: Cai Gu Huang, Tie Qiang Huang, Jun Rong Tan
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Publication number: 20240351975Abstract: The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.Type: ApplicationFiled: May 29, 2024Publication date: October 24, 2024Inventors: JIA-NING XIANG, HAO-WEI SHIH, XIAOMING WU, XUAN ZHANG, JAMES TIEN
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Publication number: 20240351976Abstract: The present invention relates to a preparation method for a sarcosinate including: step 1, reacting a solution of glyoxylic acid or a glyoxylate with an amine solution to prepare a Schiff base solution; step 2, subjecting the prepared Schiff base solution to a hydrogenation reaction under the condition of a catalyst; and step 3, adjusting a pH value of a solution obtained after the hydrogenation reaction to be alkaline to obtain the sarcosinate. Wherein the pH value of the solution obtained after the hydrogenation reaction in the step 3 is adjusted to be acidic to obtain sarcosine. Wherein a sarcosinate solution obtained in the step 3 is reacted with cyanamide to prepare a sarcosine derivative.Type: ApplicationFiled: September 12, 2023Publication date: October 24, 2024Inventors: Yong Chen, Xiquan Fang, Shaobo Li, Wei Zhou, Feng Liu, Xiang Li, Weihao Wu, Wei Zhou, Mingjiao Zhao, Na Luo
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Publication number: 20240351977Abstract: Provided herein are compounds and their pharmaceutically acceptable salts, lipid particles comprising such compounds or pharmaceutically acceptable salts thereof and compositions of the foregoing that can be used to reduce immune intolerance in a subject, for example, to treat autoimmune disorders, or in combination with an antigenic therapy, such as a protein or gene therapy, to improve the efficacy of the antigenic therapy. The compounds have the following structural formula: wherein values for the variables (e.g., X, R) are as described herein.Type: ApplicationFiled: August 12, 2022Publication date: October 24, 2024Applicant: Lapix Therapeutics, Inc.Inventors: Anas M. Fathallah, Scott D. Larsen, Abdulraouf Ramadan
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Publication number: 20240351978Abstract: The present invention provides a method for industrially producing a highly pure aromatic nitrile compound and a highly pure aromatic carboxylic acid compound safely and highly efficiently at low costs. Compound (2) is subjected to Willgerodt reaction in the presence of an additive as necessary, and the obtained amide compound (3) is hydrolyzed and neutralized to give carboxylic acid compound (4). Carboxylic acid compound (4) is reacted with a halogenating agent in the presence of a catalyst as necessary in an organic solvent, and further reacted with an amidating agent, and the obtained amide compound (5) or (6) is reacted with a dehydrating agent to give nitrile compound (1). Alternatively, carboxylic acid compound (4) is reacted with a halogenating agent and a compound represented by the formula R6SO2R7 in the presence of a catalyst as necessary in an organic solvent to give nitrile compound (1).Type: ApplicationFiled: June 10, 2024Publication date: October 24, 2024Applicant: API CORPORATIONInventors: Masaki NAGAHAMA, Hideki OOMIYA, Daiki OKADO, Hirotsugu TANIIKE
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Publication number: 20240351979Abstract: Disclosed in the present invention are a polyonium salt photoacid generator for ArF light source dry lithography, and a preparation method therefor and an application thereof. The photoacid generator is an onium salt having an anions and an onium ion, the anion having a structure as shown in formula (I), the onium ion having a structure shown in formula (A) or formula (B), and the number of onium ions keeping the charge of the onium salt neutral. A photoresist comprising the onium salt of the present invention has better resolution, sensitivity and linewidth roughness.Type: ApplicationFiled: October 19, 2021Publication date: October 24, 2024Inventors: Shunong FANG, Su WANG, Zhiyue GENG
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Publication number: 20240351980Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.Type: ApplicationFiled: May 31, 2024Publication date: October 24, 2024Applicant: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Sara Rebecca Goldstein, Do Yeon Kwon, Thomas L. Little, Markus Metz, Peter Kurt Nollert von Specht, Jennifer Tsoung
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Publication number: 20240351981Abstract: Specific bismaleimide compounds are made, and curable compositions are made that include at least one of these bismaleimides and at least one specific polyimide. A process is developed for the manufacture of these curable compositions, and crosslinked polymers are obtainable by this process. A process is developed for the manufacture of a composite material by curing a mixture of a fibrous or particulate reinforcement and the curable composition or the crosslinked polymer as well as the obtained composite material.Type: ApplicationFiled: July 22, 2022Publication date: October 24, 2024Applicant: Evonik Operations GmbHInventors: Dr. Sergey EVSYUKOV, Dr. Sabine LEICK, Dr. Stephan Kohlstruk
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Publication number: 20240351982Abstract: The disclosure relates to norpsilocin compounds, compositions containing those crystalline compounds, and methods of treatment using them. The norpsilocin compounds include crystalline 4-hydroxy-N-methyltryptamine (“crystalline 4-HO-NMT” or “crystalline norpsilocin freebase”), crystalline 4-hydroxy-N-methyltryptammonium fumarate (“crystalline norpsilocin fumarate”), and 4-hydroxy-N-methyltryptammonium fumarate (“norpsilocin fumarate”) and their compositions and uses.Type: ApplicationFiled: May 3, 2024Publication date: October 24, 2024Applicant: CAAMTECH, INC.Inventor: Andrew R. CHADEAYNE
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Publication number: 20240351983Abstract: Methods of treating mood disorders with compounds disclosed herein. Also provided are pharmaceutical compositions that include those compounds.Type: ApplicationFiled: June 28, 2024Publication date: October 24, 2024Applicant: Gilgamesh Pharmaceuticals, Inc.Inventor: Andrew Carry Kruegel
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Publication number: 20240351984Abstract: The present disclosure relates generally to inhibitors of KIF18A, compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to indoline inhibitors of KIF18A and methods of their use for treating disease mediated by KIF18A, such as cancer.Type: ApplicationFiled: June 5, 2024Publication date: October 24, 2024Applicant: Volastra Therapeutics, Inc.Inventor: Derek A. COGAN