Abstract: Disclosed are devices placed onto an endotracheal tube to create a bend in the tube at a predetermined position. In one aspect, an endotracheal tube bending apparatus comprises a backbone portion creating an angle between a proximate end of the apparatus and a distal end of the apparatus, and a plurality of curved extensions structured to capture a tubing against the backbone portion. In another aspect an endotracheal tube bending apparatus comprises a first prong attached to a base at a first proximate end and having a nub at a first distal end. A second prong and a third prong are each attached to the base at a second and third proximate ends and connected together via a bridge structure at a second and third distal ends. A pocket in the bridge is configured to capture the nub to hold the endotracheal tube in a bent position.

Abstract: An inflatable cuff for an endotracheal tube system has a sealing component that is one or a combination of (a) a proximal one-directional valve configured to deflect with underpressure during the intubation procedure and contact the tracheal wall of a patient to provide sealing, (b) a distal one-directional valve configured to deflect with overpressure during the intubation procedure and contact the tracheal wall to provide sealing; and (c) a cloud shape of the inflatable portion. The cloud shape is defined by at least one sealing section of the inflatable portion having a primary maximum inflated diameter and at least one non-sealing section of the inflatable portion having a maximum inflated diameter less than the primary maximum inflated diameter. The inflatable cuff may be inflatable by a ventilation tube. The system may include a cuff controller that senses airflow parameters and provides regulated flows of air during an intubation procedure.

Abstract: A method for providing respiratory support to a patient includes intubating the patient with an invasive patient interface having a sealable member operable to form a sealing engagement with the patient's airway. While the patient is intubated, the sealable member is operated to form a non-sealing arrangement of the invasive patient interface within the patient's airway and a flow of respiratory gas is provided to the patient via the invasive patient interface. This respiratory support is provided during absence of spontaneous breathing.

Abstract: A system and method for video assisted percutaneous needle cricothyrotomy and tracheostomy to assist physicians in quickly intubating patients suffering from respiratory distress when oral or nasal intubation is not possible or contraindicated. The system and method includes a display monitor, a percutaneous needle assembly including a connection hub having a syringe port for removably attaching a syringe, a needle port for attaching a hollow needle, and a stylet port in communication with the needle port for receiving a fiber optic stylet that extends through the hollow needle. The fiber optic stylet includes one or more illuminators, and a camera for capturing and transmitting anatomical images for display on the display monitor to visually assist physicians in locating a patient's trachea lumen. The fiber optic stylet is positioned within the trachea lumen, and used as a guide wire to insert a dilator and cannula for ventilating the patient.

Abstract: A patient interface including a seal-forming structure with an elastomeric membrane that has at least one hole such that the flow of air at a therapeutic pressure is delivered to at least an entrance to the patients nares and/or an entrance to the patients mouth. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in a cavity of a plenum chamber throughout the patients respiratory cycle, in use. The elastomeric membrane includes a first portion that is held in a relaxed state and a second portion that is held in a taut state. The elastomeric membrane is molded to include a three-dimensional shape that has multiple curvatures. The at least one hole includes an arch on a lateral side of the at least one hole, and is in a relaxed state before use. The arch is configured to move to a substantially taut state during use.

Abstract: A patient interface comprising a plenum chamber, a seal-forming structure configured to form a seal with a region of the patient's face surrounding an entrance to the patient's airways, and a vent structure configured to allow a flow of gases exhaled by the patient from an interior of the plenum chamber to ambient. The plenum chamber comprises an anterior portion comprising an inlet configured to receive a flow of air at the therapeutic pressure for breathing by the patient. The vent structure is configured to vent the flow of gases from the interior of the plenum chamber in a substantially lateral direction in use. The patient interface further comprises a deflector configured to redirect the laterally vented flow of gases. The patient interface further comprises a diffuser to diffuse the vented flow of gases.

Abstract: A diaphragm nasal breathing regulator includes a cylinder, a diaphragm, and an engaging unit. The cylinder has a channel, two openings opposite to each other along an axial direction of the cylinder, and a bearing surface allowing the diaphragm to be disposed thereon. The engaging unit engages the diaphragm to the cylinder. The diaphragm is formed with a through hole, and is movable relative to the bearing surface between an inhaling position and an exhaling position. When the diaphragm is in the exhaling position, the diaphragm rests on the bearing surface, and air can flow only through the two openings, the channel, and the through hole. When the diaphragm is in the inhaling position, the diaphragm is away from the bearing surface in the axial direction, and air can flow through the two openings, the channel, the through hole, and a gap between the cylinder and the diaphragm.

Abstract: A patient interface has a single loop headstrap and a mask for covering at least the nostrils of the user. The single loop headstrap extends from the mask at either end. A short length of supple conduit is coupled to the mask by a swivel or ball joint to allow rotation of the conduit relative to the mask through different angles and orientations.

Abstract: A medicinal diffuser system includes an air flow nasal prong. The medicinal diffuser system further includes a set of dual nasal receivers extending from a central portion of the air flow nasal prong. The medicinal diffuser system further includes a medicinal flow nasal prong positioned on top of the air flow nasal prong. The medicinal diffuser system further includes a set of medicinal distributors extending from the medicinal flow nasal prong. The medicinal diffuser system further includes a set of air flow tubes coupled to the air flow nasal prong and a medicinal flow tube coupled to the medicinal flow nasal prong.

Abstract: Disclosed is an elastomeric device and method of using to securely position a nasal cannula that is fitted to the cannula tubing between the ear and the head. The device comprises a flange and body with a cut though both. The device is positioned with the flange end located behind the ear facing the front and contacting the head. The inside diameter of the device is measurably smaller than the outside diameter of the cannula tube. The cut permits the device to be attached to the tube at point of use. Once attached the device is adjusted by the wearer to a position where the flange contacts the back of the wearer's ear and side of the head with enough tension to keep the nasal cannula in a preferred position without having to cinch a bolo slide tightly and uncomfortably.

Abstract: The present invention relates to a PAP system that uses a mask with a PAP unit and air passage to provide positive air pressure to a patient. The PAP system may have a plurality of sensors, such as but not limited to a heart rate monitor, a pulse oximeter, a microphone, a gyroscope, a pressure sensor, and an ammeter. The PAP system may further have at least one ECG sensor. The plurality of sensors may obtain a plurality of measurements, which may be analyzed by a processor. The plurality of measurements may be stored in a memory of the PAP system. The present invention further relates to a method of providing a diagnosis and/or suggesting treatment using the PAP system, as well as a method of performing a polysomnography using the PAP system.

Abstract: Mask interfaces having mask frames and mask seals are disclosed. Headgear and breathing conduits can be connected to the mask interfaces. The connection between the mask seals and the mask frames can enable movement of the mask seals relative to the mask frames. The relative movement may be at the mounting locations of the mask seals and mask frames.

Abstract: A method for producing a ventilation hose and a ventilation hose having a continuous wall, which delimits an internal lumen, converted in an extrusion and thermoforming process via thermoplastic and elastic processes from an original mold in a forming process. The lumen is designed to guide respiratory gas, a helix surrounding the wall in a spiral shape on the side facing away from the lumen. The wall is produced from a first material and the helix is produced from a second material, with the helix being connected to the wall.

Abstract: A hydrogen water generator with warning function includes a container, a gas input port, a handle, a diffusing pipe, a gas output port, and a water port. The gas input port receives gas comprising hydrogen. The diffusing pipe is configured in the containing space and coupled to the gas input port. The gas output port receives the gas comprising hydrogen in the containing space and outputs it to the outside. The water port outputs the water to the outside. The gas comprising hydrogen enters into the water in the containing space to generate hydrogen water and humidified gas comprising hydrogen to be outputted to the outside of the container through the water port and the gas output port respectively. The container emits a first color light when the system is under a normal condition, but emits a second color light when the system is under an abnormal condition.

Abstract: The present disclosure is a vapor bottle nozzle adapter that addresses issues and problems with the PZR-style vaporizers, including unpleasant odors and tastes from the silicone components, and the limitation or need to use receptacles that are proprietary and specially made for each PZR-style vaporizer device, by using, a disk component, which sits on top of the PZR-style cover and a specialized tube device, which fits into the disk component, and from which the vapor is expelled downwardly into the bottle or container. Alternatively, a third component, a modified insert component that fits into the PZR vaporizer well instead of the existing cover is used for the assembly. These two or three components work together to allow the vaporizer device to produce better tasting vapor and distribute the vapor from the vaporizer to a non-proprietary receptacle.

Abstract: The invention relates to an apparatus for supplying NO (1), such as an NO/N2 gaseous mixture, comprising a main gas circuit (40; 40.1, 40.2) with flow rate control means (42, 43) comprising at least one main solenoid valve (42) operated by the operating means (50) in order to control the flow rate of NO/N2 mixture passing through said at least one main solenoid valve (42). The main solenoid valve (42) is a proportional solenoid valve having degrees of opening of between 0 and 100%, and is configured to function in at least two given operating ranges corresponding to different degrees of opening of the main solenoid valve (42). The operating means (50) are configured to control the main solenoid valve (42) in pulsed mode in one of the operating ranges so as to deliver successive gas pulses (IG) and in proportional mode in another operating range.

Abstract: A ventilator device for co-ventilation of multiple patients may include an air tube splitter having an inlet, a plurality of outlets, and a plurality of branches each extending to a respective outlet, a plurality of valves coupled to the branches, a plurality of actuators coupled to the valves, and a controller in operable communication with the actuators. Each valve may be configured to be adjusted to regulate air flow through a respective branch. Each actuator may be configured to adjust a respective valve. The controller may be configured to receive a set of inspiratory pressure settings or tidal volume settings for the patients and independently control the actuators to adjust the valves based at least in part on the set of inspiratory pressure settings or tidal volume settings. The controller may employ time-multiplexing in controlling the actuators to adjust the valves for ventilating the patients at different times.

Abstract: A therapeutic pillowcase with a sleep-aid system is an apparatus that enables the user to have a better sleep experience. The apparatus is designed to securely and comfortably retain several therapeutic devices that help the user to fall asleep as well as to stay asleep. To do so, the apparatus includes a pillowcase body, an eye-masking sleeve, and a plurality of therapeutic inserts. The pillowcase body corresponds to the structure of the apparatus designed to cover a pillow. The pillowcase body also retains the plurality of therapeutic inserts in a secure and comfortable manner. The eye-masking sleeve helps cover the user's eyes while the user is sleeping for a more comfortable sleeping experience. The plurality of therapeutic inserts include several therapeutic devices that provide different therapeutic treatments to the user. Each of the plurality of therapeutic inserts can be attached to the pillowcase body as desired.

Abstract: A nudge management device includes: a storage unit configured to store information of a nudge which is a mechanism for prompting a user to voluntarily adopt a desirable behavior; an acquisition unit configured to acquire nudge intervention information which is information associated with intervention of a nudge; and an abrasion deriving unit configured to derive nudge abrasion information indicating a degree of decrease in effect of the nudge associated with the nudge intervention information based on the nudge intervention information and to output the derived nudge abrasion information.

Abstract: A method includes receiving, at a first computing device, data associated with the sleep session. The method further includes transmitting a first portion of the data associated with the sleep session to a second computing device. The second computing device is configured to analyze the first portion of the data to generate an initial set of one or more stimuli to be applied to the individual during the sleep session. The method further includes receiving, at the first computing device, the initial set of one or more stimuli from the second computing device. The method further includes determining, by the first computing device, a final set of one or more stimuli to apply to the individual during the sleep session based at least in part on the initial set of one or more stimuli and a second portion of the data associated with the sleep session.

Abstract: An interactive respiratory relaxation auto-biofeedback device for relieving stress characterized by at least three continuously-intercommunicated modules: at least one bladder and at least one pressure sensor in connection with the at least one bladder; the at least one bladder configured for manual actuation by a user during exhalation; at least one programmable actuator for inflating and deflating the at least one bladder; an actuating module, comprising computerized feedbacking module (CFM) for programming and controlling the programmable actuator of the at least one bladder, and a self-reporting switch for user fixing of the breathing rate set by the actuating module.

Abstract: The present disclosure describes a urinary catheter (1) with slide valve (8) provided with a tube (3) and a moving element (2) with a narrowing and a relief (5) on the end face closest to the narrowing (13), where the tube (3) is provided with another relief (6) and both reliefs are at the same end of the slide valve (8) and close to each other. The valve also has curved surfaces (7) adapted to allow the fingers to make a firm, natural and ergonomic grip of the urinary catheter (1) and press the moving element (2).

Abstract: A heart pump assembly, also referred to as catheter assembly, having a desired anatomical shape is provided. The catheter assembly can include a catheter and a cannula having a bend between a proximal portion and a distal portion. A resting shape of the catheter and the cannula can be selected to allow the distal cannula portion to be positioned at a desired angle relative to an anatomical plane (e.g., a plane of an aortic arch). In some embodiments, a packaging tray can be designed to set the catheter assembly in a desired resting shape. For example, the proximal cannula portion can be positioned at a first angle relative to the catheter, and the proximal cannula portion can be positioned at a second angle out of the plane of the packaging tray via one or more inserts.

Abstract: A medical instrument includes a hollow coil body including a winding wire that is spirally wound around a longitudinal axis of the coil body, and a cover member covering the winding wire of the coil body. The cover member includes an outer cover portion covering an outer peripheral surface of the coil body, and an inner cover portion covering an inner peripheral surface of the coil body and coupled to the outer cover portion. The inner cover portion includes a protrusion that protrudes radially inward from the coil body beyond a common tangent line of the winding wire in a longitudinal axis direction of the coil body. The protrusion is formed in a substantially annular shape around the coil body, and is disposed intermittently along the longitudinal axis direction of the coil body.

Abstract: A magnetically controllable linkage based medical device for interventional medical procedures includes a magnetic tip subassembly including magnetic elements thereon; a plurality of linkage body elements connected in sequence, wherein each linkage body element is configured for deflection in at least one deflection direction; a linkage base element coupled to a proximal linkage body element; a support body connected to the linkage base element; at least one pair of control wires passing to the magnetic tip subassembly; wherein the device is configured such that an externally-generated magnetic field deflects the magnetically-controlled linkage-based device in at least one deflection direction, and wherein selectively tensioning the control wires can hold the magnetically-controlled linkage-based device in a desired orientation.

Abstract: Methods and devices described for improved catheters including those having a deflectable section to allow for expansion while maintaining flow through a vessel.

Abstract: A catheter sheath device may include an elongate member and a moveable member. The elongate member may include a first lumen, and the moveable member may include a second lumen. The moveable member may be physically coupled to a portion of the elongate member to permit relative movement therebetween. A first relative movement between the moveable member and a portion of the elongate member may cause the second lumen to be positioned at a first location that permits delivery of at least a portion of a catheter into the second lumen but not into the first lumen from the second lumen. A second relative movement between the moveable member and the portion of the elongate member may cause the second lumen to be positioned at a second location that permits delivery of the at least the portion of the catheter through both the second lumen and the first lumen.

Abstract: A device for applying a fluid therapeutic substance to a tissue wall which surrounds a body cavity. The device is arranged on a catheter that is insertable into the body cavity and, after insertion, can be expanded radially relative to the catheter to touch the tissue wall, the fluid supplied via the catheter reaching the tissue wall via outlet openings. The catheter is designed as a tube of an endoscopic device, the tube receiving the device at its distal end and having a lumen in which a mechanical control element extends. By longitudinal movements of the control element, which are generated proximally via an actuating element, the device is adjusted between a state of smallest radial extension and a state of largest radial extension, whereby it has the outlet openings for the fluid at least in its section which touches the tissue wall in the spread-open state.

Abstract: A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. A housing has a dispense end and rotatable knob at an opposite end. The knob connecting to a screw and nut mechanism for elevating an elevator upward toward the dispense end. A component of the screw and nut mechanism exposed and extending out of at the bottom of the applicator for overriding the screw nut engagement allowing quick elevation of an elevator without rotation of the knob. The screw and nut mechanism having a platform for engaging the elevator when the screw and nut mechanism is in a fully retracted position providing stability for the elevator and visual indication of proper positioning and assembly of the applicator.

Abstract: The application provides a dissolvable microneedle device to deliver immune stimulants to the skin. The application also provides a method of treating a skin condition comprising applying a dissolvable microneedle device to the skin.

Abstract: Systems and methods are provided for delivering therapy using an applicator guide and a plurality of catheters for delivering, e.g., radiation, drug, RF, laser or ultrasound therapy. The applicator guide includes a through hole channels through which the catheters may be introduced. The through hole channels may be sized such that the plurality of catheters may freely and independently traverse the through hole channels. By positioning the applicator guide over a target area of a patient's skin, the catheters are free to make contact with the patient's skin and conform to any contours of the patient's skin. The catheters may be microneedles that may be locked in the conformed orientation, such that the microneedles may non-invasively penetrate the patient's skin to deliver the therapy transdermally. The applicator guide may be coupled to an afterloader, drug reservoir, pulse generator, and/or power generator controlled by a healthcare provider via a computing device.

Abstract: Embodiments of the invention provide solid con-trolled-release penetrating member for exposure to the intestinal lumen environment and delivery of an active agent across or within the small intestine lumen wall and having a tissue penetrating tip, especially ad-vantageous for active agents typically administered by injection. Optionally, the penetrating members include a tip coat or water insoluble extension of the controlled release formulation and/or an intestine environment protective component. Methods of using the penetrating members and arrays thereof are also provided.

Abstract: Embodiments of an actuating device for actuating a needle cartridge and puncturing an epidermis with controlled depth. The actuating device includes a motor housed in a motor housing, an actuating rod driven by the motor and configured to actuate in a reciprocating motion, and an adjustment mechanism. The actuating rod is housed in a rod housing, the rod housing forming a device aperture configured to receive a needle cartridge and to attach to the needle cartridge. The adjustment mechanism interfaces with the rod housing and is configured to adjust a position of the rod housing relative to the motor housing while not rotating the rod housing relative to the motor housing.

Abstract: A connector assembly may include an inner housing and an outer housing surrounding the inner housing. The inner housing may include a fluid flow path extending between a proximal port and a distal port. An exterior surface of the inner housing may include a first electrically conductive exterior surface and a second electrically conductive exterior surface. An interior surface of the outer housing may include a first electrically conductive interior surface and a second electrically conductive interior surface. The outer housing may be configured to move radially and rotationally relative to the inner housing. A processer may determine, based on whether the electrically conductive exterior surfaces contact the exterior electrically conductive interior surfaces, radial data associated with a radial position of the outer housing relative to the inner housing and rotational data associated with a rotational position of the outer housing relative to the inner housing.

Abstract: Embodiments in the present disclosure relate to an anchoring and centering device for a circulatory support pump. An exemplary apparatus comprises an expandable anchoring device extending along a longitudinal axis, wherein the expandable anchoring device is arranged about a central axis. A distal portion of the expandable anchoring device defines an annulus through which the cardiac pump can be arranged and to which the cardiac pump can be releasable coupled. A proximal portion of the expandable anchoring device is configured to circumferentially expand to an unconstrained configuration that has a cross-sectional diameter greater than a diameter of the annulus. The exemplary apparatus also includes a constraining member arranged over the expandable anchoring device to constrain the expandable anchoring device in a constrained configuration for delivery of the anchoring apparatus.

Abstract: A rotary pump housing having a cylindrical bore, a pumping chamber and a motor stator including an electrically conductive coil located within the housing and surrounding a portion of the cylindrical bore. A rotor has a cylindrical shaft with an impeller and one or more magnets located within the shaft that are responsive to the motor stator to drive actuation of the rotor. The housing bore is closely fitted to the outer surface of the shaft forming a hydrodynamic journal bearing with an annular clearance defining a leakage flow path. One or more of radial or axial thrust bearings may be provided to provide rotation stability to the rotor and flow within the leakage flow path. The relative orientation of positions of the inflow, outflow, and leakage flow paths may be varied within the pump, such as to accommodate different intended methods for implantation and/or use.

Abstract: A method for providing a therapeutic treatment to reduce preload may be provided. The method may include placing a ventricular assist device (VAD) at least partially within either the left or right ventricle of a patient, and placing a catheter-based device comprising an adjustable flow restricting element (FRE) such that the FRE is disposed within a superior vena cava (SVC) of the patient. The method may include receiving information from the VAD and/or the catheter-based FRE device, determining a first determined value based on the information, and controlling at least one performance parameter of the VAD and/or the catheter-based device based on the first determined value.

Abstract: Described herein are systems and methods for assessing a condition of a mechanical circulatory support device (MCSD). The systems and methods can be used for early detection of device malfunction. The system can include a sensing subsystem that can obtain from one or more sensors signals indicative of at least one of vibrations or acoustics of the MCSD in operation in the mammal. The system can also include a computing subsystem. The computing subsystem can receive the signals indicative of at least one of the vibrations or the acoustics of the MCSD in operation in the mammal. process the signals to identify at least one harmonic in the signals, and evaluate the condition of the MCSD using the at least one harmonic identified in the signals indicative of at least one of the vibrations or the acoustics of the MCSD in operation in the mammal.

Abstract: A system including a data-driven controller configured to output signals controlling a dose of therapy to a treatment site and in response to feedback comprising data representing a healing state of the treatment site measured by a sensor; and a pumping system coupled to the controller, the pumping system pumping the therapy to the treatment site.

Abstract: Various fixation techniques for implantable medical device (IMDs) are described. In one example, an assembly comprises an IMD; and a set of active fixation tines attached to the IMD. The active fixation tines in the set are deployable from a spring-loaded position in which distal ends of the active fixation tines point away from the IMD to a hooked position in which the active fixation tines bend back towards the IMD. The active fixation tines are configured to secure the IMD to a patient tissue when deployed while the distal ends of the active fixation tines are positioned adjacent to the patient tissue.

Abstract: A method for fabricating a neurostimulation stimulation lead includes providing a plurality of ring components and hypotubes. An insulative coating is disposed on at least one of (i) inner surfaces of the ring components or (ii) the hypotubes. The method includes welding the hypotubes to the inner surfaces of the ring components, and molding an insulative material to fill interstitial spaces between the ring components and the hypotubes that are welded to form a stimulation tip component of the stimulation lead. The method includes forming segmented electrodes from the ring components after performing the molding.

Abstract: An implantable cardiac electrode comprising an electrode lead and an electrode tip, wherein the electrode tip comprises a housing and a fixation screw received within the housing, wherein the fixation screw is electrically conductive connected to the electrode lead and serves for fixing the electrode tip within cardiac tissue. The housing comprises a first element and a second element, wherein the first element has a sleeve-like shape and defines a receiving space for the fixation screw, wherein the second element is at least partially inserted into the receiving space so that the first element overlaps the second element in an overlapping area, wherein the first element and the second element are bonded together in the overlapping area, wherein the first element comprises a first material being transparent for light having a first wavelength, wherein the second element comprises a second material that is absorbing for light having the first wavelength.

Abstract: Embodiments herein relate to cancer treatment systems with electrical field generating circuits. In an embodiment, an implantable field generator device is included having a housing and a field-generating circuit disposed therein. The field-generating circuit can include a circuit ground, a positive voltage output, and a negative voltage output. An equivalent series referencing resistor is connected in series between a housing and the circuit ground. A first galvanic isolation switch and a first capacitor are connected in series between the positive voltage output and a positive electrode connection terminal. A second galvanic isolation switch and a second capacitor are connected in series between the negative voltage output and a negative electrode connection terminal. Other embodiments are also included herein.

Abstract: Disclosed is an electronic device used for stimulating a target area using a targeting signal, the electronic device including at least four pairs of electrodes and at least four signal generators. Each pair of electrodes is connected to one of the at least four signal generators and the electronic device is configured to generate, using each of the at least four signal generators a total of at least four periodic carrier signals, and output, using each pair of the at least four pairs of electrodes, the at least four periodic carrier signals. A first periodic carrier signal and a second periodic carrier signal may cause temporal interference and generate a first envelope signal with a first envelope frequency, and a third periodic carrier signal and a fourth periodic carrier signal may cause temporal interference and generate a second envelope signal with a second envelope frequency.

Abstract: The present invention relates to an applicator for applying functional electrical stimulation (FES) to rehabilitate a person. The applicator includes a surround for surrounding a portion of the person. One or more electrodes are locating within the surround. The electrodes may be borne by the surround, when attaching the surround to the portion, to greatly reduce set-up time.

Abstract: The present disclosure relates to a method of treating testicular pain. The method includes externally coupling an electrical energy source to a pelvic region of a subject, and delivering electrical energy to one or more areas of the pelvic region.

Abstract: It has been discovered that pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. A method has been developed to reduce pain in a painful region following limb joint replacement by stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following total knee arthroplasty surgery or other limb joint replacement surgeries.

Abstract: An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

Abstract: A method and system for improving kidney function of a patient may be provided. The method may include activating a baroreceptor, and improving a flow of blood through vasculature of the patient. This may include positioning a stent at or near a baroreceptor, the stent configured to stretch the vasculature. This may include positioning a lead at or near a baroreceptor, the lead comprising a proximal end and a distal end and an electrode connected to the distal end of the lead, wherein the electrode configured to emit one or more electrical signals, such as an intermittent electrical stimulus or a constant electrical stimulus. The stent may include a tubular body, which may be made of a flexible material.

Abstract: Disclosed is an implantable neural stimulation device, the device comprising: an electrode array comprising a plurality of electrodes, the electrodes comprising a first stimulus electrode and a second stimulus electrode; a pulse generator connectable to the stimulus electrodes, the pulse generator configured to generate a multiphasic stimulus pulse of current from a supply voltage and deliver the multiphasic stimulus pulse via the stimulus electrodes to an electrically excitable tissue in order to evoke a neural response on a neural pathway in the electrically excitable tissue; and modulation circuitry connectable to a regulation electrode of the plurality of electrodes, the modulation circuitry configured to modulate a voltage on the regulation electrode during the delivery of the multiphasic stimulus pulse such that a corresponding voltage on each stimulus electrode varies substantially symmetrically around a value which is about half the supply voltage over the multiphasic stimulus pulse.