Abstract: Isolated anti-human CD45RC antibodies or binding fragments thereof, nucleic acids and expression vector encoding the same, compositions including the same, and uses thereof as medicaments, including for the prevention and/or treatment of CD45RChigh-related diseases (including autoimmune diseases, undesired immune responses, monogenic diseases, and lymphoma or cancer), in particular for use in preventing and/or treating graft-versus-host disease (GVHD).

Abstract: Disclosed are compositions and methods for targeted treatment of TAG-72-expressing cancers. In particular, bispecific antibodies are disclosed that are able to engage T-cells to destroy TAG-72-expressing malignant cells.

Abstract: Provided herein are compositions, methods, and uses involving anti-Mucin-16 (MUC16) agents that immunospecifically bind an epitope of Mucin-16 (MUC16). Also provided herein are uses and methods for managing, treating, or preventing disorders, such as cancer and diseases associated with positive MUC16 expression.

Abstract: As a result of producing ACE910 variants in which various sites of the constant regions were modified, the inventors discovered bispecific antibodies having FVIII mimetic activity higher than that of ACE910. The inventors also identified mutation positions that elevate the FVIII mimetic activity and discovered methods for elevating the FVIII mimetic activity by using the mutations.

Abstract: The invention relates to antibodies, and antigen-binding fragments thereof, that specifically bind TFPI and inhibit an activity thereof. Such antibodies and fragments are useful for treating bleeding disorders and shortening clotting time.

Abstract: The invention provides anti-polymeric IgA (plgA) antibodies and methods of using the same.

Abstract: The disclosure relates to compositions comprising isolated mitochondria or combined mitochondrial agents, and methods of treating disorders using such compositions.

Abstract: The present disclosure relates to compositions comprising mixtures of hydroxypropyl-?-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-?-cyclodextrins.

Abstract: A process of manufacturing a polymer product includes continuously forming a temporary container; introducing an unsaturated monomer component and a radical polymerization component into the temporary container; sealing the temporary container to form a sealed temporary container; and allowing the unsaturated monomer component to polymerize in the sealed temporary container to form the polymer product via a radical polymerization reaction.

Abstract: Water-dispersible or water-dispersed polymers are made by reacting (i) an unsaturated monomer containing one or more cyclic carbonate groups, or (ii) an unsaturated or saturated oligomer or polymer containing a plurality of cyclic carbonate groups, with a tertiary amine in the presence of an acid, or with an acid in the presence of a tertiary amine, or in the presence of an acid and a tertiary amine, to provide a water-dispersible or water-dispersed monomer, oligomer or polymer. When step a) provides a monomer or oligomer, the monomer or oligomer is reacted with one or more monomers in the presence of an initiator to provide a water-dispersible or water-dispersed polymer. When step a) provides a polymer, the polymer is optionally used to support emulsion polymerization of one or more unsaturated monomers in the presence of an initiator to provide a water-dispersible or water-dispersed further polymer.

Abstract: The present invention relates to a process for producing an aqueous polymer dispersion by free-radically initiated aqueous emulsion polymerization, and also to the aqueous polymer dispersions produced by the process and to the use of these as a binder, adhesive, sizing agent for fibers, for the production of coatings or for the production of a paper coating slip.

Abstract: Disclosed herein are a modified high cis polydiene polymer, processes for preparing the modified high cis polydiene polymer, and tire rubber compositions containing the modified high cis polydiene polymer. The processes make use of a functionalizing compound of formula I or formula II and a coupling agent to prepare the modified high cis polydiene polymer from a quantity of conjugated diene monomer polymerized using a lanthanide-based catalyst system. The modified high cis polydiene polymer includes at least one polymer chain having a residue from the functionalizing compound and a residue from the coupling agent and can be utilized in tire rubber compositions in combination with other ingredients such as fillers.

Abstract: A novel modified polypropylene resin is provided which makes it possible to provide, by an extrusion expansion method, expanded polypropylene-based resin particles having an expansion ratio which falls within a wide range and having a low open cell ratio. The novel modified polypropylene resin is obtained by a method of producing the modified polypropylene resin where the method includes a melting and kneading step of melting and kneading a particular random polypropylene resin, a conjugated diene compound, and a particular radical polymerization initiator to obtain the modified polypropylene resin.

Abstract: A water- and oil-repellent agent for fibers containing a bottle brush polymer having a structure represented by the following formula (1), wherein R1 is H or CH3; R2 is a divalent organic group; R3 is a polymer chain having a structure represented by the following formula (2) (wherein R4 is H or CH3; R5 is a C16-C40 monovalent hydrocarbon group; and n is an integer of 10 to 1000); and m is an integer of 10 to 5000:

Abstract: A diene elastomer and a rubber composition comprising the diene elastomer is provided. The diene elastomer bears pendent imidazole functions in a molar content of at most 4% of the constituent repeating units of the diene elastomer, which diene elastomer is a copolymer of ethylene and of a 1,3-diene comprising ethylene units, the ethylene units representing at least 50 mol % of the constituent repeating units of the diene elastomer, the 1,3-diene being 1,3-butadiene or isoprene. Such an elastomer confers improved uncured properties on the rubber composition.

Abstract: A thermosetting resin composition containing a maleimide compound (a) having at least one N-substituted maleimide group, and a compound (b) represented by the following general formula (1) exhibiting no reactivity with the maleimide group of the component (a) (Xb1 represents a single bond or a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 5 carbon atoms; Rb1 and Rb2 each independently represent a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 10 carbon atoms, a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 ring carbon atoms, a substituted or unsubstituted heterocyclic aromatic hydrocarbon group having 5 to 20 ring atoms, an oxygen atom-containing group, or a group containing a combination of these groups; and m and n each independently represent an integer of 0 to 5).

Abstract: A rubber composition having excellent abrasion resistance and improved viscoelasticity properties, and a tire manufactured using the same are disclosed herein. In some embodiments, a rubber composition includes a first synthetic rubber and a second synthetic rubber, and has an interaction parameter (?blend) defined by Mathematical Formula 1 at room temperature is 2.0×10?3 or more. The first synthetic rubber is a solution-polymerized modified conjugated diene-based rubber which has a 1,2-vinyl bond content of 50 wt % or more and includes a functional group bonded to at least one terminal, and the second synthetic rubber is a conjugated diene-based rubber which has a 1,2-vinyl bond content of less than 50 wt %.

Abstract: A process for producing a water-emulsifiable polyisocyanate formulation, in which, in a first process step, (A) a dispersion-active reaction product (E) is prepared from at least one diisocyanate selected from the group of hexamethylene 1,6-diisocyanate, pentamethylene 1,5-diisocyanate, 4,4?-di(isocyanatocyclohexyl)methane, 1-isocyanato-3,3,5-trimethyl-5-(isocyanatomethyl)cyclohexane, tolylene 2,4- and 2,6-diisocyanate, tetramethylxylylene diisocyanate, p-xylylene diisocyanate, 2,4?- and 4,4?-diisocyanatodiphenylmethane, with at least one mono- or polyhydric polyalkylene ether alcohol having 2 to 4 carbon atoms in the alkylene groups that comprises a polymer chain having at least 8 ethylene oxide units, and the resultant reaction product (E), in a second process step, (B) is mixed with at least one (cyclo)aliphatic polyisocyanate having an average NCO functionality of 2.2 to 5.0, preferably of 2.5 to 4.

Abstract: A thermoplastic polyurethane having a glass transition temperature of the soft phase of not more than ?25° C. measured using DMA and a heating rate of 2K/min at 1 Hz under torsion based on DIN EN ISO 6721: 2016; maximum G? can be obtained by a process at least including the reaction of a polyol composition including a polypropylene glycol, wherein the proportion of the secondary terminal OH groups based on the total number of terminal OH groups of the polypropylene glycol is in the range of more than 90%, with a polyisocyanate to obtain a polyol composition including a prepolymer and the reaction of the polyol composition including the prepolymer with a polyisocyanate composition including at least one polyisocyanate and at least one chain extender having a molecular weight <500 g/mol. The thermoplastic polyurethane may be used for producing injection molded products, extruded products, films, profiles and shaped articles.

Abstract: The present disclosure relates to materials for photoinitiated cationic ring-opening polymerization (ROP). The present disclosure also relates to uses of the materials, e.g., in 3D printing.

Abstract: An all-donor black color electrochromic polymer is disclosed as well as a method for preparing the all-donor black color electrochromic polymer. The electrochromic polymer comprises conjugated polymers, and the conjugated polymers are chemically linked, or physically blended, or both.

Abstract: The present invention describes a process of manufacturing biodegradable PET chips, comprising the steps of providing a purified terephthalic acid (PTA) in a predetermined quantity in a slurry tank; providing virgin monoethylene glycol (MEG) in a predetermined quantity in the slurry tank; transferring the combination of the slurry tank to an esterification reactor for esterification of the combination in the reactor at above 250° C. temperature which releases monomers; transferring the monomers from the esterification reactor to a polymerisation reactor; providing poly-catalysts such as, but not limited, to Ti-based catalyst, sb2O3 or any other suitable catalysts or combination thereof into the polymerisation reactor; and polymerization of the monomers in the polymerisation reactor at above 280° C. temperature, wherein an enzyme based composition is provided either at PTA/MEG stage or poly-catalyst stage or at other stages or combination thereof.

Abstract: The present invention relates to a method for the combined production of at least two target products selected from the group consisting of (T1), (T2) and (T3), wherein (T1) is a terephthalate polyester, (T2) is a copolyester on the basis of terephthalic acid, at least one aliphatic 1,?-dicarboxylic acid and at least one aliphatic 1,?-diol, and (T3) is a copolyester on the basis of terephthalic acid, polytetramethylene glycoland at least one aliphatic 1,?-diol.

Abstract: The present disclosure discloses a semi-aromatic polyamide and a preparation method therefor. The semi-aromatic polyamide is obtained by polymerization reaction using a diamine, a dibasic acid and a monoacid as main raw materials while adding a special end-capping agent. The semi-aromatic polyamide prepared according to the present disclosure has good thermal stability, a yellowness index of less than 20, a glass transition temperature of 90° C. or above, and a melting point of 300° C. or above, and can be applied to spare parts for fuel pipelines in automobiles, and electronic and electrical industries such as LED panels.

Abstract: Block copolymers have a general chemical structure of one of the formulas [A]n-[B]m and [B]n-[A]m, wherein block [A] is a poly(2-oxazine) and wherein block [B] is a poly(2-oxazoline). The block copolymers have desired thermogelling and rheological properties and are useful as carrier materials for active ingredients such as drugs, cells, proteins, and other active ingredients.

Abstract: The present invention relates to a thermosensitive hydrogel composition, which while comprising an amino acid ester, polyethylene glycol, and a functional group for the introduction of a functional moiety at an end thereof at a predetermined ratio, comprises a polyphosphazene-based polymer having a controlled length and a content of polyethylene glycol contained therein, in which a reversible sol-gel transition character is altered; a medical polymer hydrogel comprising the polyphosphazene-based polymer; or an ink composition for 3D printing.

Abstract: A method for synthesising polymers through devulcanisation from waste containing elastomers, the method including: a) contacting the waste containing elastomers with a solvent in the presence of a devulcanisation agent, b) heating the mixture produced in step a), at a temperature of between 20° C. and 250° C. for a period of between 15 minutes and 24 hours in the presence of a devulcanisation agent, the concentration of devulcanisation agent, and the ratio between the concentration of devulcanisation agent, expressed as parts per hundred of elastomer (phr) and a volume of solvent, expressed in ml, is: greater than 0.3 phr/ml of solvent or less than 0.2 phr/ml of solvent when the method is carried out in air, greater than 0.06 phr/ml of solvent when the method is carried out in an inert atmosphere.

Abstract: An embodiment of the present invention provides a coating composition comprising a composite in which a dissociated natural polymer compound is bound onto at least a portion of the surface of acrylic polymer particles.

Abstract: A resin producing method is a method of producing a resin with which an insulating structure formed on an outer peripheral portion of a conductor is impregnated, the method including: a filler mixing step of mixing a nanofiller at a ratio of 15 wt % or more with an epoxy resin to form a mixture; a shear mixing step of causing the mixture to be subjected to shear mixing; a diluent mixing step of mixing a reactive diluent that reduces a viscosity of the epoxy resin, with the mixture after the shear mixing step; and a curing agent mixing step of mixing an acid anhydride curing agent with the mixture after the diluent mixing step.

Abstract: A stretched polyester film and a method for preparing the stretched polyester film are disclosed. The stretched polyester film contains a polyester resin in which a diol component and a dicarboxylic acid component are polymerized, wherein the heat shrinkage rate of the film at 80° C. in the main shrinkage direction is 40% or more, and, upon a first thermal treatment and a second thermal treatment, a first melting temperature (Tm1) and a second melting temperature (Tm2) appear when the film is analyzed by differential scanning calorimetry (DSC). The stretched polyester film has excellent heat shrinkability, along with an increased efficiency of a recycling process of waste plastic containers.

Abstract: A silicone rubber molded body (10) has an article contact surface (11). The article contact surface (11) has a coefficient of rolling resistance lowered by a fluorination treatment on the article contact surface (11).

Abstract: Foam composites and methods of preparation thereof are discussed. For example, the foam composite may include a polymeric material and a particulate filler, wherein the compressive strength of the foam composite is equal to or greater than 20 psi, the density is 4 pcf to 40 pcf, and wherein the thermal conductivity is equal to or less than 0.050 W/n K, the particulate filler may include fly ash. e.g., in an amount of about of 45% to about 75% by weight with respect to the total weight of the foam composite. The foam composite may be prepared from a mixture of a polyol, an isocyanate, the particulate filler, and a liquid blowing agent having a boiling point equal to or greater than 25° C. or 30° C.

Abstract: The invention provides a stabilising composition for polymeric materials, comprising: a. a first derivatised phenolic antioxidant; b. at least one secondary arylamine having the formula (I): NHRyRx wherein: the or each R, which may be the same or different, independently denotes an optionally substituted hydrocarbyl group; x and y are each independently from 0 to 5 provided that at least one of x and y is at least 1; and provided that at least one R is an optionally substituted hydrocarbyl group having at least 9 carbon atoms; and c. one or more antioxidant boosters independently selected from: i. a second derivatised phenolic antioxidant having lower steric hindrance than the first derivatised phenolic antioxidant; ii. a hindered amine; iii.

Abstract: Highly transparent (up to 92% light transmittance) wood composites have been developed. The process of fabricating the transparent wood composites includes lignin removal followed by index-matching polymer infiltration resulted in fabrication of the transparent wood composites with preserved naturally aligned nanoscale fibers. The thickness of the transparent wood composite can be tailored by controlling the thickness of the initial wood substrate. The optical transmittance can be tailored by selecting infiltrating polymers with different refractive indices. The transparent wood composites have a range of applications in biodegradable electronics, optoelectronics, as well as structural and energy efficient building materials. By coating the transparent wood composite layer on the surface of GaAs thin film solar cell, an 18% enhancement in the overall energy conversion efficiency has been attained.

Abstract: The use of a mixture (M) comprising (a) from 40 to 70% by volume of an inorganic powder (IP) based on the total volume of the mixture (M), (b) from 30 to 60% by volume based on the total volume of the mixture (M) of a binder (B) comprising (b1) from 50 to 96% by weight of at least one polyoxymethylene (POM) based on the total weight of the binder (B), (b2) from 2 to 35% by weight of at least one polyolefin (PO) based on the total weight of the binder (B), (b3) from 2 to 40% by weight of at least one further polymer (FP) based on the total weight of the binder (B) in a fused filament fabrication process.

Abstract: A low-density, halogen-free epoxy composition that is flame-resistant upon curing and is suitable for use as a potting compound. The epoxy composition includes: (a) an epoxy component; (b) at least one curative; (c) at least one latent curing accelerator; (d) a toughening component that includes nano-sized core shell rubber (CSR) particles having particle size of less than 1 micron; (e) a fire-retardant component that is halogen-free; and (f) hollow microspheres for reducing the density of the composition. The fire-retardant component includes a mixture of: (i) at least one polyphosphate; (ii) at least one metal borate; and (iii) at least one compound selected from alkaline earth metal hydroxides and aluminum hydroxides.

Abstract: The present invention relates to an optical filter containing: an absorption layer containing a near-infrared absorbing dye (A) having a maximum absorption wavelength in dichloromethane being in a wavelength range of 850 to 1,100 nm and a transparent resin; and a reflection layer formed of a dielectric multilayer film, in which the near-infrared absorbing dye (A) satisfies the following Formulae (1) to (4). ABS400(A)DCM/ABS?max(A)DCM<0.10??(1), ABS550(A)DCM/ABS?max(A)DCM<0.04??(2), ABS400(A)TR/ABS?max(A)TR<0.15??(3), and ABS550(A)TR/ABS?max(A)TR<0.10??(4).

Abstract: To provide a marking ink composition for a writing board having excellent erasability of drawn lines, the marking ink composition essentially containing a pigment, a pigment dispersant resin, a masking agent, and a modified polyvinylalcohol or a polyvinylalcohol having a degree of saponification from 40 to 84% by molar ratio.

Abstract: A light emitting element ink and a method of manufacturing a display device are provided. The light emitting element ink includes a light emitting element solvent, a light emitting element dispersed in the light emitting element solvent, the light emitting element including a plurality of semiconductor layers and an insulating film surrounding outer surfaces of the semiconductor layers, a thickener dispersed in the light emitting element solvent, wherein a compound of the thickener includes a functional group capable of forming a hydrogen bond together with a compound of the light emitting element solvent or another compound of the thickener and the compound of the thickener is represented by Chemical Formula 1.

Abstract: An ink set includes a reaction liquid containing coagulant; a first ink containing a color material; and a second ink containing a color material. The ink set is used for recording on a non-absorptive recording medium or a low-absorptive recording medium and for imparting the reaction liquid, the first ink, and the second ink to the recording medium in a superimposed manner in this order.

Abstract: A curable resin composition comprising; component (A) monofunctional 2-(allyloxymethyl) acrylic acid or its ester; component (B) a polyfunctional radically polymerizable compound having an isocyanurate ring; component (C) a radically polymerizable compound; component (D) rubber particles; and component (E) a radical polymerization initiator, the component (C) is a radically polymerizable compound different from the component (A) and the component (B); and when the sum of the component (A), the component (B) and the component (C) is 100 parts by mass, the component (B) is 20 parts by mass or more to 80 parts by mass or less and the component (C) is 0 parts by mass or more to 40 parts by mass or less.

Abstract: Polymerizable liquids for 3D printing applications are described herein which, in some embodiments, impart flame resistant and/or flame retardant properties to articles printed from the liquids. The polymerizable liquids may also impart desirable mechanical properties to the articles. In some embodiments, a polymerizable liquid comprises a curable isocyanurate component in an amount of at least 5 wt. %, based on total weight of the polymerizable liquid, and a brominated acrylate ester component. Additionally, methods of printing three-dimensional articles using said polymerizable liquids are described herein.

Abstract: Articles including durable and icephobic and/or biocidal polymeric coatings are disclosed. The polymeric coatings can include a bonding layer which may contain a substantially fully cured polymeric resin providing excellent adhesion to metallic or polymer substrates. The polymeric coating further includes an outer surface layer which is smooth, hydrophobic, biocidal and icephobic and, in addition to a substantially fully cured resin, contains silicone comprising additives near the exposed outer surface. The anisotropic polymeric coatings are particularly suited for strong and lightweight parts required in aerospace, automotive and sporting goods applications. A process for making the articles is disclosed as well.

Abstract: The present disclosure relates to a matting agent including polymer particles, a matting polymer composition including a matting agent, and a method of producing polymer particles. The polymer particles may be produced by a simple process using a suspension polymerization method, and is relatively easy to control a degree of crosslinking. In addition, in a case where a matting polymer composition is prepared using a matting agent including the polymer particles, it is possible to manufacture a molded article having excellent appearance and matting effect without deterioration of the existing mechanical properties such as impact strength and tensile strength of a thermoplastic polymer, and in particular, an excellent matting effect may be exerted even in the extrusion processing, which has been difficult to achieve in the related art.

Abstract: An adhesive resin composition including a propylene polymer (A), an ethylene polymer (B), and a thermoplastic resin (C) including a copolymer containing not less than 60 mol % and not more than 99 mol % of structural units derived from 4-methyl-1-pentene, and not less than 1 mol % and not more than 40 mol % of structural units derived from a C2-C20 ?-olefin other than 4-methyl-1-pentene, these structural units representing total 100 mol % of the copolymer, the thermoplastic resin (C) showing a melting point Tm of not more than 199° C. or showing substantially no melting point as analyzed with a differential scanning calorimeter (DSC). The total of the components (A), (B) and (C) includes 45 to 75 parts by mass of the component (A), 5 to 20 parts by mass of the component (B), and 15 to 45 parts by mass of the component (C).

Abstract: A method of manufacturing an adhesive member includes providing, for a substrate, a resin composition having a viscosity of about 5 cP to about 50 cP, as measured according to JISK2283 method, at about 25° C. The resin composition is exposed to a first light to form a preliminary adhesive member having a curing rate of about 80% to about 98%. The preliminary adhesive member is exposed to a second light having a light integral/dose that is more than that of the first light to form an adhesive member. The preliminary adhesive member may have a loss tangent (tan ?) of about 0.2 to about 0.6 and may have a glass transition temperature of about ?70° C. to ?30° C. Accordingly, the preliminary adhesive member and adhesive member formed by the method of manufacturing an adhesive member may exhibit increased reliability.

Abstract: Hot melt adhesives comprising (i) styrene butadiene copolymer, (ii) olefin block copolymer (OBC), and (iii) water white hydrogenated hydrocarbon resin are described. The adhesives exhibit high optical clarity and are relatively clear over a wide range of temperatures. The adhesives also exhibit good adhesion at cold temperatures. Also described are laminates of the adhesive with polymeric films, such as adhesive labels that can be used in labeling containers. In addition, various goods such as containers labeled using the adhesives are described.

Abstract: The present invention relates to a urethane prepolymer having an isocyanate group, a viscosity at 100° C. of 30 to 600 dPa·s, and a thermal softening temperature after moisture curing of 75 to 155° C.

Abstract: The inventive perforated tape is a masking tape that has an elongate tape member further having a polymer coating top layer, a biodegradable paper mask layer middle layer, and a biodegradable polymer perforated lining member contiguously coupled to a bottom surface of the paper mask layer, a plurality of hole members parallelly disposed laterally and longitudinally substantially covering the entire polymer perforated lining member. The polymer perforated lining member further includes a plurality of solid portions of the polymer perforated lining member disposed laterally and longitudinally between the plurality of hole members adapted to resist tear so the elongate tape member tears substantially perpendicularly to longitudinal sides of the elongate tape member along a user-selected one row of a plurality of linear rows of hole members. An adhesive compound is disposed substantially on the entire bottom surface of the perforated lining member.

Abstract: Various embodiments disclosed relate to a surfacing film. The surfacing film includes a base layer. The base layer includes a thermoplastic polyurethane film comprising a reaction product of a reaction mixture of a diisocyanate, a polyester polyol having a melting temperature of at least about 30° C.; and a diol chain extender. There are many reasons to use the surfacing film including easier and more cost effective manufacturing of the surfacing film by directly extruding the base layer by mixing the reaction mixture in an extruder. Another reason to use the surfacing film is that the film has improved resistance to discoloration. Another reason to use the film is that the film shows good toughness.