Patents Issued in December 24, 2024
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Patent number: 12173360Abstract: In some embodiments, provided herein is an integrated assay of a biological sample comprising an in situ assay module and a spatial assay module. The in situ assay comprises analyzing binding between nucleic acid probes and a first analyte at a spatial location of the biological sample. In some embodiments, the method further comprises providing conditions to allow spatially barcoded capture agents to capture a second analyte for analysis in the spatial assay module.Type: GrantFiled: February 19, 2021Date of Patent: December 24, 2024Assignee: 10X GENOMICS, INC.Inventors: Felice Alessio Bava, Zachary Bent
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Patent number: 12173361Abstract: Provided herein are methods and systems and related composition, to provide a rodent model having a target microbiome profile formed by a target presence, a target proportion and/or a target total load of a target prokaryote of a target taxon, based on absolute quantification of the target prokaryote. Further provided are rodents obtained by the methods herein described and related use in testing methods performed in connection with physiological or pathological conditions in an individual preferably a human individual. Also provided herein is a tailcup device and related use to prevent coprophagia in rodents.Type: GrantFiled: January 13, 2021Date of Patent: December 24, 2024Inventors: Rustem F Ismagilov, Jacob T Barlow, Said R Bogatyrev
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Patent number: 12173362Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.Type: GrantFiled: November 5, 2021Date of Patent: December 24, 2024Assignee: Exact Sciences CorporationInventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
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Patent number: 12173363Abstract: Provided herein are methods and systems for absolute quantification of a target 16S rRNA and/or of a target prokaryotic taxon, based on amplifying and sequencing a same 16S rRNA recognition segment in which target 16S rRNA conserved regions flank 16S rRNA variable regions, conserved and variable among a plurality of sample 16S rRNAs and/or of a sample prokaryotic taxon of higher taxonomic rank with respect to the target taxon. In the methods and systems, absolute abundance of the a plurality of sample 16S rRNAs and/or of the sample prokaryotic taxon detected by the amplifying, is multiplied by the relative abundance of the target 16S rRNA and/or of a target prokaryotic taxon detected by the sequencing to provide the absolute quantification in accordance with method and systems of the disclosure.Type: GrantFiled: July 12, 2022Date of Patent: December 24, 2024Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Rustem F. Ismagilov, Jacob T. Barlow, Said R. Bogatyrev
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Patent number: 12173364Abstract: The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore.Type: GrantFiled: April 27, 2020Date of Patent: December 24, 2024Assignee: Oxford University Innovation LimitedInventors: David Jackson Stoddart, Andrew John Heron, Giovanni Maglia, John Hagan Pryce Bayley
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Patent number: 12173365Abstract: The present disclosure provides methods and systems for nucleic acid sequencing. Such systems and methods may achieve context-independent incorporation, have reduced context-dependence or have context-dependence that is amenable to calibration and modeling. Such systems and methods may also reduce misincorporation.Type: GrantFiled: April 5, 2022Date of Patent: December 24, 2024Assignee: Ultima Genomics, Inc.Inventors: Gilad Almogy, Linda Lee
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Patent number: 12173366Abstract: This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.Type: GrantFiled: May 5, 2022Date of Patent: December 24, 2024Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventors: Jingyue Ju, Shiv Kumar, Zengmin Li, Chuanjuan Tao, Minchen Chien, James J. Russo, Sergey Kalachikov, Ken Shepard, Jacob Karl Rosenstein
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Patent number: 12173367Abstract: A method of forming a plurality of lipid bilayers over an array of cells in a nanopore based sequencing chip is disclosed. Each of the cells comprises a well. A salt buffer solution is flowed over the array of cells in the nanopore based sequencing chip to substantially fill the wells in the cells with the salt buffer solution. A lipid and solvent mixture is flowed over the array of cells to deposit the lipid and solvent mixture over at least some of the wells in the cells. A first portion of the cells, each having a lipid bilayer over its well, is detected. A second portion of the cells, each having a lipid membrane but not a lipid bilayer over its well, is detected. An electrical lipid-thinning stimulus is selectively applied to the second portion of the cells but not to the first portion of the cells.Type: GrantFiled: October 6, 2023Date of Patent: December 24, 2024Assignee: Roche Sequencing Solutions, Inc.Inventors: Kevin Aliado, Roger J. A. Chen, Jing Luo, J. William Maney, Jr., William Nielsen, Kyle Umeda, Ashraf Wahba
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Patent number: 12173368Abstract: The present disclosure relates, according to some embodiments, to compositions and analysis of RNA (e.g., dephosphorylated oligoribonucleotides) including, for example, natural and/or synthetic RNAs. A composition may comprise, for example, an endoribonuclease having an amino acid sequence that (i) corresponds to an amino acid sequence of a first species (e.g., Homo sapiens, Escherichia coli, Aspergillus oryzae, Momordica charantia, Pyrococcus furiosus, Cucumis sativus, and Sus scrofa) or (ii) is a non-naturally occurring sequence; and/or an RNA end repair enzyme having an amino acid sequence that (i) corresponds to an amino acid sequence of a species other than the first species (e.g., a bacterial species or a bacteriophage species) or (ii) is a non-naturally occurring sequence.Type: GrantFiled: April 10, 2023Date of Patent: December 24, 2024Assignee: New England Biolabs, Inc.Inventors: Ivan R. Correa, Jr., Eric Wolf, Nan Dai, Erbay Yigit, Sebastian Grünberg
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Patent number: 12173369Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.Type: GrantFiled: April 1, 2020Date of Patent: December 24, 2024Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATEDInventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
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Patent number: 12173370Abstract: The present invention relates to methods for haplotype determination and, in particular, haplotype determination at the whole genome level as well as targeted haplotype determination.Type: GrantFiled: October 18, 2021Date of Patent: December 24, 2024Assignee: Ludwig Institute for Cancer Research LtdInventors: Bing Ren, Siddarth Selvaraj, Jesse Dixon, Anthony Schmitt
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Patent number: 12173371Abstract: This disclosure is directed to the discovery of an improved method to diagnose malignant melanoma of the oral cavity in the dog.Type: GrantFiled: December 23, 2019Date of Patent: December 24, 2024Assignee: North Carolina State UniversityInventor: Matthew Breen
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Patent number: 12173372Abstract: It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting liver cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: October 20, 2023Date of Patent: December 24, 2024Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Satoshi Kondou, Hitoshi Nobumasa, Satoko Kozono, Hiroko Sudo, Junpei Kawauchi, Atsushi Ochiai, Motohiro Kojima
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Patent number: 12173373Abstract: The invention provides a selecting method for domestic rabbits with a agouti/Belgian hair color based on homozygous genotype selection. The purification method is applicable to purification of various domestic rabbits with the agouti/Belgian hair color. The method includes the following steps: firstly, selecting the domestic rabbits with a hair color phenotype which is the agouti/Belgian hair color; then detecting an ASIP gene, a MC1R gene and a TYR gene at the same time by utilizing a first primer set, a second primer set and a third primer set; screening the domestic rabbits with genotypes of AA (corresponding to the ASIP gene), EE (corresponding to the MC1R gene) and CC (corresponding to the TYR gene). The domestic rabbits with the genotype of AAEECC, which are obtained by the screening method of the invention, are agouti/Belgian hair color homozygotes and the recessive white gene is eliminated.Type: GrantFiled: April 26, 2021Date of Patent: December 24, 2024Assignees: SHANDONG AGRICULTURAL UNIVERSITY, QINGDAO KANGDA RABBIT INDUSTRY DEVELOPMENT CO., LTD.Inventors: Xinzhong Fan, Yongxu Liu, Xibo Qiao, Chunhui Hui, Hong Zhao, Mingyong Li, Bo Wang, Aiguo Yang, Jiaqing Hu
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Patent number: 12173374Abstract: The invention provides systems and methods for analyzing viruses by representing viral genetic diversity with a directed acyclic graph (DAG), which allows genetic sequencing technology to detect rare variations and represent otherwise difficult-to-document diversity within a sample. Additionally, a host-specific sequence DAG can be used to effectively segregate viral nucleic acid sequence reads from host sequence reads when a sample from a host is subject to sequencing. Known viral genomes can be represented using a viral reference DAG and the viral sequence reads from the sample can be compared to viral DAG to identify viral species or strains from which the reads were derived. Where the viral sequence reads indicate great genetic diversity in the virus that was infecting the host, those reads can be assembled into a DAG that itself properly represents that diversity.Type: GrantFiled: May 26, 2023Date of Patent: December 24, 2024Assignee: Seven Bridges Genomics Inc.Inventors: Devin Locke, Piotr Szamel
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Patent number: 12173375Abstract: A rapid amplification method for a nucleic acid of hepatitis B virus, comprises the following steps: mixing a sample containing hepatitis B virus with a nucleic acid releasing agent, and adding a PCR premix to obtain a reaction solution, the PCR premix comprising deoxyribonucleoside triphosphate, an upstream primer as shown in the sequence SEQ ID NO: 1, a downstream primer as shown in the sequence SEQ ID NO: 2, a DNA polymerase and an amplification buffer; placing the reaction solution in a PCR reaction tube so that the reaction solution is in a form of a thin film with a thickness of 0.1 mm or less; performing PCR amplification under the following reaction condition: pre-denaturation at 90 to 100° C. for 10 s to 600 s, denaturation at 90 to 100° C. for 0 to 1 s, and annealing and extending at 50-65° C. for 0 to 1 s.Type: GrantFiled: January 31, 2019Date of Patent: December 24, 2024Assignee: SANSURE BIOTECH INC.Inventors: Lizhong Dai, Xu Fan
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Patent number: 12173376Abstract: A method of manufacturing iron in a metallurgical vessel, the vessel including a bath of molten iron with on top of the bath of molten iron a layer of slag, wherein a metalliferrous feed, carbon containing material, fluxing material, and oxygen or an oxygen-containing gas are introduced into the vessel to convert the metalliferrous feed into molten iron that is collected in the bath of molten iron and continuously or semi-continuously tapped from the vessel through an iron—outlet of the vessel, and wherein the composition of the fluxing material is selected to acquire a predetermined slag chemistry, which slag is regularly tapped out of the vessel through a slag—outlet, and the fluxing material includes slag derived from a steelmaking process.Type: GrantFiled: March 3, 2020Date of Patent: December 24, 2024Assignee: TATA STEEL NEDERLAND TECHNOLOGY B.V.Inventors: Hendrikus Koenraad Albertus Meijer, Petrus Gerardus Jacobus Broersen, Johan Willem Koenraad Van Boggelen
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Patent number: 12173377Abstract: The grain-oriented electrical steel sheet is a grain-oriented electrical steel sheet which does not have an inorganic coating containing forsterite as a main component, including a base steel sheet having a predetermined chemical component, a silicon-containing oxide layer provided on the base steel sheet, an iron-based oxide layer provided on the silicon-containing oxide layer, and a tension-insulation coating provided on the iron-based oxide layer, having a thickness of 1 to 3 ?m, and containing phosphate and colloidal silica as main components. When elemental analysis is performed from a surface of the tension-insulation coating in a sheet thickness direction by glow discharge optical emission spectrometry, predetermined requirements are satisfied.Type: GrantFiled: January 16, 2020Date of Patent: December 24, 2024Assignee: NIPPON STEEL CORPORATIONInventors: Kazutoshi Takeda, Ichiro Tanaka, Tomoya Suenaga, Takashi Kataoka, Yuki Kunita
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Patent number: 12173378Abstract: The method for manufacturing a grain-oriented electrical steel sheet is a method for manufacturing a grain-oriented electrical steel sheet including a strain region forming process of irradiating the grain-oriented electrical steel sheet having a base steel sheet (1), an intermediate layer (4) disposed to be in contact with the base steel sheet (1), and an insulation coating (3) disposed to be in contact with the intermediate layer (4) with an electron beam and forming a strain region (D) which extends in a direction intersecting a rolling direction of the base steel sheet (1) on a surface of the base steel sheet (1), wherein, in the strain region forming process, a temperature of a central portion of the strain region (D) in the rolling direction of the base steel sheet (1) and an extension direction of the strain region (D) is heated to 800° C. or higher and 2000° C. or lower.Type: GrantFiled: January 16, 2020Date of Patent: December 24, 2024Assignee: NIPPON STEEL CORPORATIONInventors: Satoshi Arai, Yoshiyuki Ushigami, Hideyuki Hamamura, Shinji Yamamoto, Shunsuke Okumura
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Patent number: 12173379Abstract: Disclosed are a non-oriented electrical steel sheet and a manufacturing method therefore, the sheet ensuring excellent magnetic characteristics by having increased texture intensity of surface (100) through strict control of the content ratio of Si, Al and the like and through final annealing heat treatment in an inert gas atmosphere.Type: GrantFiled: September 29, 2020Date of Patent: December 24, 2024Assignee: LG Electronics Inc.Inventors: Jin Bae Kim, Dongwon Kang, Joungwook Kim
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Patent number: 12173380Abstract: This steel sheet has a predetermined chemical composition, and includes, as a metallographic structure, ferrite, bainite, and pearlite in a total volume percentage of 0% or more and 50% or less, residual austenite in a volume percentage of 3% or more and 20% or less, and a remainder of fresh martensite and tempered martensite, in which residual austenite having an aspect ratio of 3.0 or more occupies 80% or more of a total residual austenite by area ratio, the steel sheet includes an internal oxide layer having a thickness of 4.0 ?m or more from a surface of the steel sheet and a decarburized layer having a thickness of 10 ?m or more and 100 ?m or less from the surface of the steel sheet, and an amount of diffusible hydrogen included in the steel sheet is 1.00 ppm or less on a mass basis.Type: GrantFiled: December 24, 2021Date of Patent: December 24, 2024Assignee: NIPPON STEEL CORPORATIONInventors: Eriko Tsukamoto, Kengo Takeda
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Patent number: 12173381Abstract: The present invention belongs to the technical field of preparation of light metal alloy materials, in particular to a method for producing a magnesium-lithium alloy by a gaseous co-condensation method. The method comprises the steps of: 1) mixing and briquetting a lithium salt, a refractory agent and a catalyst under pressure, and then thermally decomposing to form an unsaturated composite oxide; 2) respectively crushing and ball-milling, and then briquetting the unsaturated composite oxide, magnesium oxide, a reducing agent and a fluxing agent; 3) reducing briquettes in vacuum; 4) making a gas pass through a first condensing chamber of a temperature control device, and then purifying; 5) The purified metal gas is condensed into the condensing phase of the alloy through the second condensing chamber of a quenching device; 6) obtaining the magnesium-lithium alloy with a purity being 99.5% or above by virtue of smelting and flux-refining, and then purifying by distillation.Type: GrantFiled: September 17, 2020Date of Patent: December 24, 2024Assignee: SICHUAN UNION SHINE NEW ENERGY SCI-TECH CO., LTDInventors: Jun Zhou, Guangli Zhang, Pei Yang, Yong Gan
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Patent number: 12173382Abstract: A combustion ash handling method of handling combustion ash discharged from a combustion furnace that combusts a petroleum-based fuel includes: separating the combustion ash into a heavy component and a light component by a dry-type separation technique; feeding the light component to the combustion furnace as a fuel; and recovering the heavy component. A metal such as vanadium is separated and extracted from the heavy component of the combustion ash.Type: GrantFiled: April 24, 2020Date of Patent: December 24, 2024Assignee: KAWASAKI JUKOGYO KABUSHIKI KAISHAInventors: Hiroyuki Mori, Seiji Tabata, Suguru Yabara, Tomohiro Osawa
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Patent number: 12173383Abstract: A continuous process for converting metal compound particles into a mixture of elemental metals. Metal compound particles and a reductant are introduced into an ultra-high temperature reaction zone having a temperature greater than 2,700° C. and an oxygen content less than 3 vol. %. The metal compound particles have particle sizes of d90 500 ?m. The metal compound particles have a residence time less than 1 minute in the ultra-high temperature reaction zone sufficient to mix with and react with the reductant to reduce the metal compound particles to form a mixture of elemental metals. The mixture of elemental metals is removed from the ultra-high temperature reaction zone. One or more elemental metals are separated or concentrated from the mixture of elemental metals within one or more separation zones based on differential size and density of the one or more elemental metals and the remaining mixture of elemental metals.Type: GrantFiled: September 21, 2023Date of Patent: December 24, 2024Assignee: Omnis Advanced Technologies, LLCInventors: James S. Swensen, Simon K. Hodson
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Patent number: 12173384Abstract: Disclosed herein are magnesium alloy based objects and methods of making and use thereof. For example, disclosed herein are methods of making a magnesium alloy based object, the methods comprising: heating an object comprising a preliminary magnesium alloy at a first temperature for a first amount of time, the preliminary magnesium alloy comprising a first intermetallic phase, a second intermetallic phase, and an alloy phase, to thereby substantially dissolving the first intermetallic phase into the alloy phase to form an object comprising an intermediate magnesium alloy, the intermediate magnesium alloy comprising the second intermetallic phase and the alloy phase; and heating the object comprising the intermediate magnesium alloy at a second temperature for a second amount of time to thereby substantially dissolving the second intermetallic phase into the alloy phase and minimizing incipient melting of the alloy phase to form the magnesium alloy based object.Type: GrantFiled: August 6, 2020Date of Patent: December 24, 2024Assignee: Ohio State Innovation FoundationInventors: Aihua Luo, Thomas Avey
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Patent number: 12173385Abstract: The present disclosure relates to an aluminum alloy material, and specifically to a weldable in-situ nano-strengthened rare-earth metal (REM)-containing aluminum alloy with high strength and toughness and a preparation method thereof. In the present disclosure, in-situ nano-ceramic particles and REMs simultaneously introduced into an Al—Zn—Mg alloy can effectively refine the grains and significantly improve the strength and toughness of the alloy; and REM-containing nano-precipitated phases and in-situ nanoparticles distributed in the grains or at grain boundaries can also significantly increase a recrystallization temperature of the alloy, effectively inhibit the dynamic recovery, reduce the re-dissolution of alloying elements, and improve the weldability of the alloy.Type: GrantFiled: June 3, 2021Date of Patent: December 24, 2024Assignee: Jiangsu UniversityInventors: Xizhou Kai, Yutao Zhao, Yanjie Peng, Gang Chen, Ruikun Chen, Lin Wu, Ran Tao, Xiangfeng Liang
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Patent number: 12173386Abstract: An antimicrobial alloy includes titanium, niobium, and silver. Further, the antimicrobial alloy includes between 5 and 30 atomic percent niobium, up to 3 atomic percent silver, the remaining atomic percentage is titanium, and the alloy does not include zirconium. The antimicrobial alloy has a predominantly beta-titanium crystal structure and an elasticity modulus ranging from 60 to 85 GPa. A process for manufacturing the antimicrobial alloy. The antimicrobial alloy prepared by the method can be used in bioimplants.Type: GrantFiled: May 4, 2023Date of Patent: December 24, 2024Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Mohamed Abdrabou Hussein, Mohammed Abdul Azeem, Arumugam Madhan Kumar, Ahmad Asaad Sorour
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Patent number: 12173387Abstract: The present invention relates to conductive multicomponent multiphase metal alloy. The metal alloy has the following (in atom-%):Ni, in a total amount of 35-70; wherein the remaining 30-65 comprises at least three elements selected from the list consisting of Sn, Nb, Ta, B, Cr, Ce, Fe, La, Nd, Sm, Gd, Ti, Zr, Mn, Hf, Si, P, Al, Y and V in a total amount of at least 30. The metal alloy comprises at least three distinct crystalline phases, at least one phase being an intermetallic phase. The present invention also relates to an electrode material comprising said alloy, to a method for forming a coating on said alloy, and to a method for manufacturing said alloy.Type: GrantFiled: December 18, 2020Date of Patent: December 24, 2024Assignee: VSCA ASInventors: David Jarvis, Rosanna Jarvis
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Patent number: 12173388Abstract: Disclosed is an iron-manganese alloy including, by weight: 25.0%?Mn?32.0%; 7.0%?Cr?14.0%; 0?Ni?2.5%; 0.05%?N?0.30%; 0.1?Si?0.5%; and optionally 0.010%?rare earths?0.14%. The remainder being iron and residual elements resulting from manufacturing.Type: GrantFiled: January 22, 2019Date of Patent: December 24, 2024Assignee: APERAMInventors: Pierre-Louis Reydet, Marielle Escot, Nicolas Laurain
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Patent number: 12173389Abstract: Provided is an alloy powder capable of obtaining a magnetic member therefrom in which the frequency FR is extremely high. The powder for the magnetic member is composed of a plurality of flaky particles. These flaky particles are composed of an Fe-based alloy including: 6.5% by mass or more and 32.0% by mass or less of Ni; 6.0% by mass or more and 14.0% by mass or less of Al; 0% by mass or more and 17.0% by mass or less of Co; and 0% by mass or more and 7.0% by mass or less of Cu; the balance being Fe and unavoidable impurities. The average thickness Tav of this powder is 3.0 ?m or less. The saturation magnetization Ms of this powder is 0.9 T or more. The coercive force iHc of this powder is 16 kA/m or more. This Fe-based alloy has a structure resulting from spinodal decomposition.Type: GrantFiled: March 13, 2020Date of Patent: December 24, 2024Assignee: Sanyo Special Steel Co., Ltd.Inventors: Kodai Miura, Toshiyuki Sawada, Ryohei Hosomi
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Patent number: 12173390Abstract: A manufacturing method of an electrical steel sheet according to an embodiment of the present invention includes: hot-rolling a slab to manufacture a hot-rolled sheet; removing some of scales formed on the hot-rolled sheet and leaving a scale layer having a thickness of 10 nm or more; controlling roughness of the hot-rolled sheet in which the scale layer remains; cold-rolling it to manufacture a cold-rolled sheet; and annealing the cold-rolled sheet.Type: GrantFiled: November 26, 2019Date of Patent: December 24, 2024Assignee: POSCO CO., LTDInventor: Hyun Jong Kim
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Patent number: 12173391Abstract: High strength steel sheet and plated steel sheet having high plateability, LME resistance, and hydrogen embrittlement resistance, that is, steel sheet containing C: 0.05 to 0.40%, Si: 0.2 to 3.0%, Mn: 0.1 to 5.0%, and sol. Al: 0.4 to 1.50%, having an internal oxidation layer including fine granular oxides, coarse granular oxides, and grain boundary oxides in a surface layer of the steel sheet, a number density of fine granular oxides in the internal oxidation layer being 4.0/?m2 or more, a number density of coarse granular oxides in the internal oxidation layer being 4.0/25 ?m2 or more, having a Ratio A of the length of the grain boundary oxides projected on the surface of the steel sheet to the length of the surface of the steel sheet when examining a cross-section of the surface layer of the steel sheet being 50% or more and 100% or less, and including a surface depleted layer with a steel composition not including oxides which satisfies, by mass %, Si?0.6% and Al?0.Type: GrantFiled: March 14, 2022Date of Patent: December 24, 2024Assignee: NIPPON STEEL CORPORATIONInventors: Keitaro Matsuda, Takuya Mitsunobu, Masaaki Uranaka, Jun Maki, Hiroshi Takebayashi
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Patent number: 12173392Abstract: Disclosed is an austenitic stainless steel having an increased yield ratio. The disclosed austenitic stainless steel is characterized by comprising, in percent by weight (wt %), 0.1% or less (exclusive of 0) of C, 0.2% or less (exclusive of 0) of N, 1.5 to 2.5% of Si, 6.0 to 10.0% of Mn, 15.0 to 17.0% of Cr, 0.3% or less (exclusive of 0) of Ni, 2.0 to 3.0% of Cu, and the remainder of Fe and other inevitable impurities, and satisfying Expressions (1) and (2) below. 3.2?5.53+1.4Ni?0.16Cr+17.1(C+N)+0.722Mn+1.4Cu?5.59Si?7??Expression (1): 551?462(C+N)?9.2Si?8.1Mn?13.7Cr?29(Ni+Cu)?110??Expression (2): wherein C, N, Si, Mn, Cr, Ni, and Cu indicate the content (wt %) of respective elements.Type: GrantFiled: July 8, 2020Date of Patent: December 24, 2024Assignee: POSCOInventors: Seokweon Song, Hak Kim, Mi-nam Park
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Patent number: 12173393Abstract: An Fe-based nanocrystalline alloy is represented by Composition Formula, (Fe(1-a)M1a)100-b-c-d-e-gM2bBcPdCueM3g, where M1 is at least one element selected from the group consisting of Co and Ni, M2 is at least one element selected from the group consisting of Nb, Mo, Zr, Ta, W, Hf, Ti, V, Cr, and Mn, M3 is at least two elements selected from the group consisting of C, Si, Al, Ga, and Ge but necessarily includes C, and 0?a?0.5, 1.5<b?3, 10?c?13, 0<d?4, 0<e?1.5, and 8.5?g?12.Type: GrantFiled: January 9, 2023Date of Patent: December 24, 2024Assignee: SAMSUNG ELECTRO-MECHANICS CO., LTD.Inventors: Sang Kyun Kwon, Han Wool Ryu, Chul Min Sim, Chang Hak Choi, Jong Suk Jeong
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Patent number: 12173394Abstract: A metal matrix composite comprising nanotubes; a method of producing the same; and a composition, for example a metal alloy, used in such composites and methods, are disclosed. A method for continuously infiltrating nanotube yarns, tapes or other nanotube preforms with metal alloys using a continuous process or a multistep process, which results in a metal matrix composite wire, cable, tape, sheet, tube, or other continuous shape, and the microstructure of these infiltrated yarns or fibers, are disclosed. The nanotube yarns comprise a multiplicity of spun nanotubes of carbon (CNT), boron nitride (BNNT), boron (BNT), or other types of nanotubes. The element that infiltrates the nanotube yarns or fibers can, for example, be alloyed with a concentration of one or more elements chosen such that the resulting alloy, in its molten state, will exhibit improved wetting of the nanotube material.Type: GrantFiled: December 29, 2017Date of Patent: December 24, 2024Assignee: American Boronite CorporationInventors: Pavel Bystricky, David S. Lashmore, Iva Kalus-Bystricky
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Patent number: 12173396Abstract: A mask frame includes a support substrate including a plurality of inner side surfaces. The plurality of inner side surfaces defines a first opening through the support substrate. A heat dissipation plate is disposed on the plurality of inner side surfaces. A plurality of fixing portions is disposed between the support substrate and the heat dissipation plate. The plurality of fixing portions includes a plurality of adhesive portions attaching the support substrate to the heat dissipation plate.Type: GrantFiled: August 7, 2023Date of Patent: December 24, 2024Assignee: Samsung Display Co., Ltd.Inventors: Jongyoon Lee, Seungjin Lee
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Patent number: 12173397Abstract: The invention relates to a sputtering target, a coating system, and a coating method for same. The sputtering target comprises a base plate with a target plate which is secured thereon and which is made of a first sputtering material with a surface and a plurality of recesses formed therein. A plurality of inserts are arranged in the recesses. At least some of the inserts are made of a second sputtering material, wherein the second sputtering material has a higher sputter yield than the first sputtering material. The aim of the invention is to achieve especially uniform coatings. This is achieved in that the inserts made of the second sputtering material are shaped such that the extent D1, D2 of the inserts, measured in a measuring direction parallel to the surface, increases from the surface to the base plate in a depth direction T.Type: GrantFiled: February 22, 2022Date of Patent: December 24, 2024Assignee: CemeCon AGInventors: Oliver Lemmer, Werner Kölker, Jürgen Balzereit, Stephan Bolz
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Patent number: 12173398Abstract: A Cr—Si sintered body contains Cr and Si. The Cr—Si sintered body contains a crystalline CrSi2 phase and a crystalline Si phase. A content of the Si phase in the Cr—Si sintered body is 40% by mass or more. A relative density of the Cr—Si sintered body relative to a true density of the Cr—Si sintered body is 95% or more. The CrSi2 phase has an average crystal grain size of 40 ?m or less, and the Si phase has an average crystal grain size of 30 ?m or less. A total content of impurities in the Cr—Si sintered body is 200 ppm by mass or less, and the impurities are composed of at least one element selected from the group consisting of Mn, Fe, Mg, Ca, Sr, and Ba.Type: GrantFiled: March 24, 2021Date of Patent: December 24, 2024Assignee: TOSOH CORPORATIONInventors: Hiroyuki Hara, Masami Mesuda, Ayaka Masuda
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Patent number: 12173399Abstract: Methods of mitigating line bending during feature fill include deposition of an amorphous layer and/or an inhibition treatment during fill.Type: GrantFiled: August 18, 2020Date of Patent: December 24, 2024Assignee: Lam Research CorporationInventors: Anand Chandrashekar, Lei Guo, Tsung-Han Yang
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Patent number: 12173400Abstract: A substrate processing device with improved exhaust efficiency and process reproducibility includes: a plurality of reactors; a plurality of exhaust ports in communication with the plurality of reactors and symmetrically arranged with respect to the reactors, respectively; and a plurality of exhaust channels in communication with the plurality of exhaust ports, wherein each exhaust channel includes a plurality of exhaust channels including a first channel extending in the first direction and a second channel extending in a second direction different from the first direction, wherein the plurality of exhaust channels extend through components supporting at least a portion of the plurality of reactors.Type: GrantFiled: August 30, 2023Date of Patent: December 24, 2024Assignee: ASM IP Holding B.V.Inventor: JaeMin Roh
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Patent number: 12173401Abstract: A method for manufacturing a semiconductor device including a TiN film. The method comprises: supplying TiCl4 gas to a substrate; purging the TiCl4 gas; supplying NH3 gas to the substrate; purging the NH3 gas; and supplying an inhibitor that inhibits adsorption of TiCl4 or NH3 to the substrate. A plurality of cycles each including the supplying the TiCl4 gas, the purging the TiCl4 gas, the supplying the NH3 gas, and the purging the NH3 gas are performed, at least a part of the plurality of cycles includes the supplying the inhibitor, and after the supplying the inhibitor is performed, the supplying the TiCl4 gas or the supplying the NH3 gas is performed without purging the inhibitor, or, after purging the inhibitor for a shorter time than the purging the TiCl4 gas or the purging the NH3 gas, the supplying the TiCl4 gas or the supplying the NH3 gas is performed.Type: GrantFiled: September 14, 2020Date of Patent: December 24, 2024Assignee: Tokyo Electron LimitedInventors: Zeyuan Ni, Taiki Kato
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Patent number: 12173402Abstract: A method of forming a transition metal containing films on a substrate by a cyclical deposition process is disclosed. The method may include: contacting the substrate with a first vapor phase reactant comprising a transition metal halide compound comprising a bidentate nitrogen containing adduct ligand; and contacting the substrate with a second vapor phase reactant. A method for supplying a transition metal halide compound comprising a bidentate nitrogen containing ligand to a reaction chamber is disclosed, along with related vapor deposition apparatus.Type: GrantFiled: July 13, 2020Date of Patent: December 24, 2024Assignee: ASM IP Holding B.V.Inventors: Timo Hatanpää, Katja Väyrynen, Mikko Ritala, Markku Leskelä
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Patent number: 12173403Abstract: Disclosed are Group 6 transition metal-containing thin film forming precursors to deposit Group 6 transition metal-containing films on one or more substrates via vapor deposition processes.Type: GrantFiled: April 30, 2021Date of Patent: December 24, 2024Assignee: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges ClaudeInventors: Rocio Alejandra Arteaga Muller, Raphael Rochat, Antonio Sanchez, Jean-Marc Girard, Nicolas Blasco, Santiago Marques-Gonzalez, Clément Lansalot-Matras, Jooho Lee, Zhiwen Wan
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Patent number: 12173404Abstract: A method of depositing one or more epitaxial material layers, a device structure formed using the method and a system for performing the method are disclosed. Exemplary methods include coating a surface of a reaction chamber with a precoat material, processing a number of substrates, and then cleaning the reaction chamber.Type: GrantFiled: February 24, 2021Date of Patent: December 24, 2024Assignee: ASM IP Holding B.V.Inventors: Amir Kajbafvala, Caleb Miskin
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Patent number: 12173405Abstract: A processing apparatus includes: a processing container having a substantially cylindrical shape and provided with an exhaust slit on a side wall; and a plurality of gas nozzles extending in a vertical direction along an inside of the side wall of the processing container, disposed symmetrically with respect to a straight line connecting a center of the processing container and a center of the exhaust slit, and each configured to eject a same processing gas into the processing container.Type: GrantFiled: September 13, 2021Date of Patent: December 24, 2024Assignee: TOKYO ELECTRON LIMITEDInventors: Hiroki Iriuda, Yoichiro Chiba, Atsushi Endo
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Patent number: 12173406Abstract: A device for depositing a thick metal nitride on a sample by supercritical fluids includes a first enclosure forming a first closed volume; a second enclosure placed in the first enclosure and delimited by internal walls transparent to electromagnetic radiation forming a second closed volume intended to include fluid under supercritical conditions; a heat transfer dielectric fluid circulating in the first volume around the second enclosure; a sample holder present in the second volume; an induction heating device surrounding the second enclosure; inlets for introducing a fluid and at least one precursor material into the second enclosure, and an outlet to purge the second volume.Type: GrantFiled: July 21, 2021Date of Patent: December 24, 2024Assignees: SAFRAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Marjorie Christine Cavarroc, Cyril Aymonier, Baptiste Simon Giroire, Bertrand Guillaume, Angélique Nadine Jeanne Poulon, Guillaume Aubert
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Patent number: 12173407Abstract: Red rust staining of Al/Zn coated steel strip in “acid rain” or “polluted” environments can be minimised by forming the coating as an Al—Zn—Si—Mg alloy coating with an OT:SDAS ratio greater than a value of 0.5:1, where OT is the overlay thickness on a surface of the strip and SDAS is the measure of the secondary dendrite arm spacing for the Al-rich alpha phase dendrites in the coating. Red rust staining in “acid rain” or “polluted” environments and corrosion at cut edges in marine environments can be minimised in Al—Zn—Si—Mg alloy coatings on steel strip by selection of the composition (principally Mg and Si) and solidification control (principally by cooling rate) and forming Mg2Si phase particles of a particular morphology in interdendritic channels.Type: GrantFiled: August 8, 2023Date of Patent: December 24, 2024Assignee: Bluescope Steel LimitedInventors: Ross McDowall Smith, Qiyang Liu, Bryan Andrew Shedden, Aaron Kiffer Neufeld, Joe Williams, David James Nolan, Wayne Renshaw
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Patent number: 12173408Abstract: An aqueous conversion coating solution comprises a trivalent chromium compound, a zirconate compound, and a dye compound. The trivalent chromium compound can comprise trivalent chromium compounds such as trivalent chromium sulfate. The dye compound can comprise an azo dye, a chromium complex dye, an anthraquinoid dye, and/or a methine dye. The zirconate compound can comprise alkali metal hexafluorozirconate compounds. The conversion coating solution can comprise a phosphorous compound such as an organic amino-phosphonic acid compound. The conversion coating solution can be formed by mixing a dye additive containing the dye with a trivalent chromium conversion coating solution that does not contain a dye. The conversion coating solution can be used to treat metal substrates comprising aluminum, magnesium, and/or zinc.Type: GrantFiled: December 31, 2019Date of Patent: December 24, 2024Assignee: Chemeon Surface Technology, LLCInventors: Sjon Westre, Taylor James Clarke, Jake Cruson
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Patent number: 12173409Abstract: A process for the deposition of a coating on at least a part of a metallic substrate, a) mixing a liquid and a powder having particles of a metallic material to be deposited and particles of a pickling agent, so as to prepare a suspension, b) application of the suspension prepared in step a) to at least a part of the surfaces of the metallic substrate, so as to obtain a substrate-suspension assembly, c) carrying out a heat treatment of the assembly which includes heating at a first temperature of at least 500° C. and heating at a second temperature greater than the first temperature, and d) recovery of a substrate coated, at least in part, with a coating, the pickling agent being a halogenated compound and the suspension having from 10% to 60% of the pickling agent, with respect to the total weight of the powder.Type: GrantFiled: October 16, 2020Date of Patent: December 24, 2024Assignee: L'Air Liquide, Societe Anonyme Pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventors: Sébastien Doublet, Nicolas Ramenatte, Stéphane Mathieu, Michel Vilasi, Léo Portebois
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Patent number: 12173410Abstract: An improved coating used in plastic processing applications including a first layer system that includes at least one corrosion resistant material layer; a second layer system that includes at least one abrasion resistant material layers; and a transition layer provided between the first layer and the second layer. The coating is resistant to both abrasion and corrosion, while maintaining ductility and impact resistance.Type: GrantFiled: November 14, 2019Date of Patent: December 24, 2024Assignee: Oerlikon Surface Solutions AG, PfäffikonInventors: Hamid Bolvardi, Ali Khatibi, Jürgen Ramm, Mirjam Arndt, Florian Neff