Abstract: Medical systems and devices include an elongate probe configured for insertion into a patient, where the elongate probe includes an atraumatic tip and where the atraumatic tip can include one or more of a loop, a curl, coil, a flexible distal region, and a steerable distal region. The distal region can be configured to transition away from a first shape toward a second shape upon insertion of the elongate probe within the patient. The optical fiber can include sensing core fibers configured to facilitate a determination of a physical state of the elongate probe. The elongate probe can also be configured to project illuminating light away from a distal end and receive imaging light at the distal end. The elongate probe can include a catheter.

Abstract: Certain aspects relate to manually and robotically controllable medical instruments. A manually and robotically controllable medical instrument can include an elongated shaft articulable by pull wires. The elongated shaft can be connected to an instrument handle that attaches to an instrument drive mechanism. The instrument handle can include a pulley assembly on which the pull wires can be mounted. Rotation of the pulley assembly can actuate the pull wires to cause articulation of the elongated shaft. The medical instrument also includes a manual drive input connected to the pulley assembly such that manual actuation of the manual drive input causes rotation of the first pulley assembly and a robotic drive input configured to engage with a robotic drive output of the instrument drive mechanism such that rotation of the first robotic drive output causes rotation of the pulley assembly.

Abstract: Tissue modification devices are provided. Aspects of the devices include an elongated member having a proximal end and a distal end. The distal end of the elongated member is dimensioned to pass through a minimally invasive body opening and includes a distal end integrated visualization sensor and tissue modifier. In some instances, the devices further include an integrated articulation mechanism that imparts steerabilily to at least one of the visualization sensor, the tissue modifier and the distal end of the elongated member. Also provided are methods of modifying internal target tissue of a subject using the tissue modification devices.

Abstract: Surgical systems are disclosed. Surgical systems can include evacuation systems for evacuating smoke, fluid, and/or particulates from a surgical site. A surgical evacuation system can be intelligent and may include one or more sensors for detecting one or more properties of the surgical system, evacuation system, surgical procedure, surgical site, and/or patient tissue, for example.

Abstract: Medical devices and related methods are described, including a medical device that includes a shaft defining at least one working channel extending from a proximal end of the shaft to a distal end of the shaft along a longitudinal axis and a distal tip coupled to the shaft. The working channel may have a cross-sectional dimension that allows passage of an instrument therethrough. The distal tip may include a first arm and a second arm, the first arm being moveable relative to the second arm between a first configuration that obstructs a portion of the working channel and a second configuration that provides unobstructed access to the working channel, e.g., to allow the instrument to extend distal to the medical device.

Abstract: An imaging head of a medical scope comprises a capsule that encapsulates an image sensor and electronics associated with the image sensor. The imaging head further comprises a light guide, within or attached to the capsule, that conveys illumination to a field of view of the image sensor. The imaging head can be disassembled by breaking or cutting the capsule to separate the image sensor and the electronics from the light guide. The imaging head is manufactured by encapsulating the image sensor and electronics, and optionally also the light guide, in a capsule. The light guide may be overmoulded in a first overmoulding step to embed the light guide in an overmoulded body. The image sensor and electronics may then be positioned beside or against the overmoulded body and overmoulded in a second overmoulding step to complete the capsule.

Abstract: An imaging device includes multiple pixels. When a first mode is set, at least one pixel of the multiple pixels sets a state of a transfer switch to an ON state and outputs a first pixel signal in accordance with an electric charge held in a floating diffusion. When a second mode is set, the at least one pixel sets the state of the transfer switch to an OFF state, sets a state of the reset switch to the ON state, and outputs a second pixel signal in accordance with the electric charge held in the floating diffusion in an output period.

Abstract: A control device includes one or more processors including hardware, the one or more processors being configured to: generate a white light image based on a first image signal captured as a result of irradiating a subject with a white light; generate a narrow-band light image based on a second image signal captured as a result of irradiating the subject with a narrow-band light; control a light intensity of the white light to a first value which is determine according to brightness of the white light image and according to a first ratio; and control a light intensity of the narrow-band light to a second value which is determine according to brightness of the narrow-band light image and according to a second ratio that is different than the first ratio.

Abstract: An endoscope cleaning device includes a base, a battery pack, and a pull tab. The base includes a cylindrical body defining a canal. The battery pack includes a battery and a heating mechanism thermally coupled to the cylindrical body. The pull tab includes a body and an annular seal detachably coupled to the body. The annular seal is in registration with the canal of the cylindrical body. The pull tab is partially received within the battery pack to inhibit electrical communication between the battery and the heating mechanism. The body of the pull tab is removably supported with respect to the base and the battery pack such that when the pull tab is pulled by a user, the annular seal detaches from the body of the pull tab and remains with respect to the cylindrical body to form a fluid-tight seal against the endoscope.

Abstract: An improved image foveation method is described employing a more complete digital model of the retina and coordination of one or more nodes for foveated image creation, processing, compression and display.

Abstract: Methods, systems, and devices to improve the assessment of visual function and overcoming limitations of current methods to identify the visual function that potentially could be reached by a given eye. Multiple eye tests including visual stimuli plus optical measurement components, and methods to combine the results, identify and quantify sources of decreased vision resulting from optical sources, such as a lens and cornea as distinguished from retinal sources. By identifying potentially correctable optical sources of decreased vision, and overcoming physiological limitations such as size of the eye's pupil, the visual benefits of treatment such as by cataract or cornealsurgery are distinguished from retinal pathology that requires medical intervention. The devices and methods provide metrics that include an expected value of the visual function and sources of variability including both optical and neural components, to guide treatment and improve clinical trials.

Abstract: A method for determining the sensitivity of at least one eye of a test subject based on at least two provided pairs of values for visual acuity and refraction, wherein at least one of the pairs of values for visual acuity and refraction. The method includes: projecting a target with an adjustable target refraction into the at least one eye of the test subject, wherein the target is configured to verify a predetermined visual acuity; and determining a visual acuity limiting refraction of the at least one eye of the test subject associated with the predetermined visual acuity by varying the target refraction of the target projected into the at least one eye of the test subject and detecting a test subject action which results in a determination that the identifiability of the target for the test subject has changed at the time of the test subject action.

Abstract: A system includes a reflective mask positioned in a first plane, a digital micromirror device (DMD) that is positioned in a second plane to receive transmitted light from the reflective mask via a non-confocal channel. The DMD includes micromirrors that rotate between an ON state and an OFF state. The system further includes an ON image detector that captures ON image data of the transmitted light directed by the micromirrors in the ON state and an OFF image detector that captures OFF image data of the transmitted light directed by the micromirrors in the OFF state. A method of image reconstruction includes using the captured data to compare against artificial image data created by a machine learning model/reconstruction network and iteratively updating weights (e.g., of the machine learning model/reconstruction network) for generating an artificial image from the artificial image data until a minimum threshold is reached.

Abstract: Head-worn computers with eye-imaging systems include a camera system positioned in a head-worn computer, wherein the camera system is further positioned to capture eye-image light that originates as reflections from a user's eye, wherein the camera system is further positioned to capture eye-image light as a reflection from a partially reflective surface that is positioned in front of an image display in the head-worn computer, wherein image light, from the image display, is transmitted through the partially reflective surface. A processor is adapted to cause the camera system to capture the eye-image light. The processor is further adapted to cause a comparison of the captured eye-image light with a pre-stored eye image of a known user of the head-worn computer. In the event the comparison confirms the identity of the known user, the user is granted permission to view content to be presented in a display of the head-worn computer.

Abstract: A method of generating three dimensional shapes for a cornea and lens of an eye, the method including illuminating an eye with multiple sections of light and obtaining multiple sectional images of said eye based on said multiple sections of light. For each one of the obtained multiple sectional images, the following processes are performed: a) automatically identifying arcs, in two-dimensional space, corresponding to anterior and posterior corneal and lens surfaces of the eye by image analysis and curve fitting of the one of the obtained multiple sectional images; and ) determining an intersection of lines ray traced back from the identified arcs in two-dimensional space with a known position of a section of space containing the section of light that generated the one of the obtained multiple sectional images, wherein the determined intersection defines a three-dimensional arc curve.

Abstract: An ambulatory medical device includes a sensor configured to acquire a signal indicative of a physiological condition of a patient, a controller operatively coupled to the sensor and configured to monitor the physiological signal, and to perform a diagnostic test, and a remote access manager operatively coupled to the controller and configured to monitor for a command from a remote system to perform the diagnostic test, and to cause the controller to perform the diagnostic test in response to the command. In the device, the remote access manager may be further configured to transmit data representing an operational status of the ambulatory medical device to the remote system. The operational status of the controller may result from performing the diagnostic test. The remote access manager may be further configured to send the data representing the operational status of the ambulatory medical device in real time or substantially in real time.

Abstract: Configuring and utilizing a body area network (BAN) is provided. In a configuration phase, configuration messages are sent for scheduling a plurality of transmit-only devices such that during a data collection phase each of the plurality of transmit-only devices is configured to transmit in an individually-assigned time slot. In the data collection phase, a data collector device receives, from the plurality of transmit-only devices, sensor data messages including sensor data from the transmit-only devices, the sensor data messages being scheduled according to the configuration phase.

Abstract: A housing of an in-vivo implantable medical device includes a window including a nonmetallic biocompatible material that enables formation of an electromagnetic resonance field and radio communication. In plan view of the housing, an outer shape of the window is larger than an outer shape of a power receiving coil. An outer shape of a magnetic sheet is larger than the outer shape of the power receiving coil to form a magnetic circuit that serves as a main magnetic flux that forms an electromagnetic resonance field to obtain power for the power receiving coil. A radio communication antenna is at a position where the main magnetic flux does not intersect. An outer shape of the radio communication antenna has an area of 1/100 or less of the outer shape of the power receiving coil.

Abstract: A method and system for assessing tissue to determine a presence or absence of cancer cells. The method includes acquiring fluorescence lifetime (FLT) data from tissue and processing the FLT data to determine a FLT signal at each of a plurality of locations across the tissue. The method also includes determining FLT data at any of the plurality of locations above a threshold indicative a presence of cancer cells and generating a report indicating any of the plurality of locations above the threshold as indicative the presence of cancer cells.

Abstract: A skin diagnosis system includes a user terminal including a camera and a dedicated application, and a skin measurement device detachably provided on the user terminal. The skin measurement device includes a body part formed to be detachably provided on the user terminal, an optical part, which is arranged at the body part, includes one or more lenses, and adjusts, to the camera, measurement light reflected from a subject in a state in which the body part is mounted on the user terminal, a light source module, which includes a white light source portion for emitting white light and a UV light source portion for emitting UV light and radiates the white light or the UV light toward the subject, a communication part enabling communication with the user terminal, and a power source for providing power.

Abstract: An intraoral scanner generates 2D images of a dental site and 3D intraoral scans of the dental site. The computing device receives the 2D images of the dental site and the 3D intraoral scans of the dental site from the intraoral scanner, generates a 3D model of the dental site based on the 3D intraoral scans of the dental site, and processes at least one of a) one or more of the 2D images of the dental site, b) one or more of the 3D intraoral scans of the dental site, or c) data from the 3D model of the dental site to identify one or more intraoral areas of interest (AOIs) at the dental site. The computing device determines a dental condition associated with the one or more intraoral AOIs, and determines a manner for scanning the one or more intraoral AOIs.

Abstract: A 3D scanner system for detecting and/or visualizing cariogenic regions in teeth based on fluorescence emitted from the teeth, the 3D scanner system including data processing means configured for mapping a representation of fluorescence emitted from the teeth onto the corresponding portion of a digital 3D representation of the teeth to provide a combined digital 3D representation.

Abstract: A method to form images of internal parts of objects that are of such a nature that images are smeared out due to scattering. The method consists in using isolated beams of radiation along specific, chosen directions, then separating radiation that have not suffered scattering events, from the radiation that have suffered scattering events. The directions may be fixed either by having a multiplicity of radiation emitters along several directions or by moving one or more radiation emitter, or a combination of these. Collimators may also be used to select the direction of radiation propagation. The invention also discloses transparent windows pressed against the object, which serves to keep the incident radiation along a known direction. The radiation that suffered scattering may be also used to make a separate images of the internal parts of the object.

Abstract: An apparatus may be configured to control a light source system residing in or on a first support structure portion of the apparatus to transmit light through an ear volume residing between a first ear portion and a second ear portion. The apparatus may be configured to receive, from a receiver system residing in or on a second support structure portion of the apparatus proximate the second ear portion, receiver system signals corresponding to acoustic waves caused by a photoacoustic response to light emitted by the light source system of a) a blood vessel residing within the ear volume, b) blood within the blood vessel, or a combination thereof. The control system may be configured to estimate one or more cardiac features based, at least in part, on the receiver system signals.

Abstract: An apparatus and associated method of manufacture may include a receiver system that includes an array of receiver elements, in addition to receiver system circuitry. A least a portion of the array of receiver elements is transparent. The transparency allows light to pass through so that blood vessel behind may be visible or otherwise perceived. In this manner, the receiver system may detect (i.e., through the transparent portion of the receiver elements) acoustic waves corresponding to the blood vessel's photoacoustic response to light emitted by a light source system that includes a light-emitting component.

Abstract: Mixed sensor array devices are provided herein. Mixed sensor arrays as described herein include acoustic energy generating elements and optical fiber based acoustic sensors. Optical fiber based sensors may optical structures responsive to physical parameters including acoustic signals, pressure, and temperature, and are configured to detect and receive acoustic signals and other physical parameters and provide associated optical signals to a system for processing and interpretation to implement tracking, location, imaging, and other sensing capabilities. Optical fiber based sensors provided herein may be disposed at ends of or along the length of optic fibers. Optical fiber based sensors may be included within various devices, including, for example, medical devices.

Abstract: A transponder is used for tracking a position of a distal end of a medical device in an ultrasound image and/or enhancing an ultrasound image.

Abstract: The present invention relates to a portable non-invasive hemodynamic monitoring system that obtains various parameters related to cardiovascular function, including blood oxygen saturation, perfusion index, pulse wave, electrocardiogram, respiration, bioimpedance, etc., and analyzes the collected data to obtain parameter data such as cardiac output, non-invasive blood pressure, cardiac index, pulmonary arterial pressure (PAP), etc.

Abstract: A wearable electronic device may be provided that includes a first image sensor oriented to capture luminance of an area of skin around a user's eye when wearing the wearable electronic device and a second image sensor oriented to capture luminance of an area of skin around the user's nose when wearing the wearable electronic device. The wearable electronic device further includes a processor configured to determine a pulse signal based on changes in luminance captured over time using at least one of the first image sensor or the second image sensor.

Abstract: Systems and methods are provided for remote patient management and monitoring. The patient is monitored with a wireless sensor system connected to an application executing on a patient user computing device. The system continuously monitors physiological parameters, such as, but not limited to, blood oxygen saturation (SpO2), pulse rate, perfusion index, pleth variability index, and/or respiration rate from the photoplethysmograph. The system triggers alarms if the patient physiological data violates thresholds. Care providers review patient data and associated alarm(s) with graphical user interfaces.

Abstract: Systems and methods include capturing sound using an ear device having one or more device settings to control device operations; amplifying sound using an amplifier with gain and amplitude controls for a plurality of frequencies; providing a hearing test over the plurality of frequencies and adjusting the amplifiers for hearing; and applying a learning machine to automatically adjust one or more device settings.

Abstract: Some disclosed devices include a light source system, an ultrasonic receiver system and a control system. The control system may be configured to receive first sensor signals, including ultrasonic receiver signals, from the ultrasonic receiver system and to estimate one or more blood vessel features based on the first sensor signals. The control system may be configured to receive second sensor signals from a second sensor and to estimate a PWV based on the first sensor signals and the second sensor signals. The control system may be configured to estimate blood pressure based, at least in part, on the one or more blood vessel features and the PWV.

Abstract: Disclosed herein is an apparatus for detecting biometric information, including a finger stall, a pulse wave sensor, an analog front end, and a microcontroller unit. The finger stall includes a mechanical structure or a gasbag. The pulse wave sensor includes a light emitter and a photodiode. The analog front end is electrically connected to the pulse wave sensor, and is configured to receive an electrical signal and output an analog front end signal. The microcontroller unit is electrically connected to the analog front end, and is configured to receive the analog front end signal and output the biometric information, the biometric information including a blood pressure value. The apparatus for detecting biometric information can enable a miniaturization of a blood pressure measuring apparatus, facilitate offering portability for users, and achieve blood pressure monitoring for the users in a non-household environment.

Abstract: A deep learning-based blood pressure estimation system using a photoplethysmography (PPG) signal detection ring is provided. The system may include a server, and the server may include a signal feature extraction component configured to extract PPG features from a PPG signal by using a first deep learning model, a user feature extraction component configured to extract user features, by using a second deep learning model, from a first test PPG signal measured using the PPG signal detection ring, systolic and diastolic test blood pressures measured using a conventional blood pressure monitor simultaneously with the first test PPG signal, and user information, and a blood pressure estimation component configured to estimate systolic and diastolic blood pressures from the PPG features and the user features by using a third deep learning model, wherein the PPG signal is measured using the PPG signal detection ring, and the server receives the PPG signal from the PPG signal detection ring through a terminal.

Abstract: A pulse wave estimating device includes processing circuitry configured to; acquire a captured image of a human; detect a skin region of the human on the captured image; set, as a plurality of measurement regions for extracting luminance signals representing luminance changes, regions formed by dividing the skin region on the captured image in a predetermined manner; extract the luminance signals on a basis of the luminance changes in the measurement regions on the captured image; and estimate a pulse wave of the human on a basis of the extracted luminance signals; perform measurement region resetting, when a ratio of measurement regions, in which the number of pixels is equal to or greater than a preset reference value among the set plurality of measurement regions, is lower than a threshold, in such a manner as to make the ratio of measurement regions equal to or higher than the threshold.

Abstract: The invention of heart rate estimation from facial images using image processing and self-adaptive matrix noise removal relates to heart rate detection through image processing and machine learning algorithms which involves the analysis of skin color changes and incorporates noise removal techniques by identifying the most reliable points and employing a self-adaptive matrix. This system employs a high-quality camera to capture video footage of a person's face and also through sophisticated image processing and machine vision methods, the system monitors and analyzes the subtle color changes in the facial skin caused by the contraction and expansion of blood vessels with each heartbeat.

Abstract: A detection device including a main body case where at least part of a main surface has an opening, a board which is provided in the main body case, a first detection portion which is provided under the board in the main body case and detects biological information of a user, a window portion which is provided under the first detection portion and is in the opening of the main body case, and a second detection portion which is provided between the board and the window portion and detects, through the window portion, whether or not the detection device is in contact with or close to the skin of the user.

Abstract: A lung fluid monitor monitors a fluid level in a lung and includes: a radiation source disposable on a first body surface and that produces nascent radiation, the nascent radiation: being received by the first body surface, communicated from the first body surface to a lung, attenuated proportionately to an amount of fluid in the lung, and communicated from the lung to a second body surface as attenuated radiation; a radiation detector disposable on the second body surface opposing the first body surface and in electromagnetic communication with the radiation source via the lung and that: receives the attenuated radiation from the lung and produces a detector signal from the attenuated radiation in response to receiving the attenuated radiation.

Abstract: The exemplified intrinsic phase space tomography methods and systems facilitate the analysis and evaluation of complex, quasi-periodic system by generating computed phase-space tomographic images as a representation of the dynamics of the quasi-periodic cardiac systems. The computed phase-space tomographic images can be presented to a physician to assist in the assessment of presence or non-presence of disease.

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

Abstract: A system and devices provide for accurate localization of orthopedic implants based on magnetic tracking approach (MTA) technology and without radiation. The system includes at least one magnetic beacon that is joined to an orthopedic screw/implant fixed to a patient's spine. A detector in the form of a magnetic sensor array detects the magnetic field from the beacon and produces an electrical signal in response thereto. A computer using a multi-objective magnetic location algorithm tracks the spatial position and movement of the beacon based on the electrical signal, and hence tracks the patient's spine.

Abstract: A diagnostic device and method for detection of a respiratory system infection of a subject, comprising a particle detecting unit configured for obtaining data related to particles being exhaled from the subject's airways, a processing unit for determining the respiratory system infection based on the data from the particle detecting unit and subject related properties.

Abstract: In one embodiment, a method includes detecting, by a motion sensor of a mobile device worn by a user, multiple motion signals, each representing a motion of the user about one of a number of mobile-device axes defined by an orientation of the mobile device. The method further includes determining, for each of the multiple mobile-device axes, a ballistocardiogram (BCG) signal based on the motion signal corresponding to that mobile-device axis; selecting, based on a strength of the determined BCG signals, one or more particular mobile-device axes and corresponding motion signals for estimating a user's tidal volume; determining, based on the one or more selected motion signals, one or more breathing features; and estimating, by providing the one or more breathing features to a trained machine-learning model, the user's current tidal volume.

Abstract: A foot pronation estimation apparatus includes a pronation estimator that estimates a degree of pronation of a foot, with reference to comparison between a feature value of a predetermined part and a reference value. A feature value extractor extracts, from a top-view image, feature values of a plurality of parts including at least a width of foot and an amount of a recess of an arch shape. A pronation estimator estimates a degree of pronation of the foot, with reference to comparison of each of the feature values of the plurality of parts including at least the foot width and the amount of the recess of the arch shape, with an individually corresponded reference value. The feature values of the plurality of parts further include foot length and an amount of protrusion in an outline shape near a little toe ball.

Abstract: An electronic device includes at least one processor that identifies a cyclic change related to an arm swing of a user from a three-dimensional acceleration measured by a measurer. The at least one processor defines a two-dimensional plane containing a plane of the arm swing of the user from the three-dimensional acceleration measured at a wrist of the user, detects the cyclic change as a motion on an arc centered at a shoulder of the user in the two-dimensional plane, obtains, from the three-dimensional acceleration, a direction of a line segment connecting the wrist and the shoulder, and obtains a bending angle of an elbow of the user based on the line segment.

Abstract: A gait training system according to an embodiment includes a load distribution sensor having a plurality of sensors arranged in a two-dimensional array to detect a distribution of a load applied from a user, and an inference device that has a CNN for performing a convolutional calculation process using two-dimensional data based on sensor outputs of the sensors as an input, and that estimates a value of the load received from the user.

Abstract: A gait training system according to an embodiment includes: a treadmill having a belt on which a user lands; a load distribution sensor that has a plurality of sensors arranged in a two-dimensional array and detects a load applied through the belt; a sensor output acquisition unit that acquires sensor outputs from the sensors of the load distribution sensor; a correction unit that corrects the sensor outputs from the respective sensors based on a moving speed of the belt; and a value-of-load calculation unit that calculates a value of a load received from the user based on corrected values corrected by the correction unit.

Abstract: A gait analysis is provided by passively sensing footstep-induced floor vibrations during walking using vibration sensors mounted on, within or under a floor. The approach is non-intrusive, scalable, and perceived as more privacy-friendly, making it suitable for continuous gait health monitoring in daily life. The floor vibration-based gait analysis framework estimates various gait parameters, including temporal parameters (step, stride, stance, swing time) and spatial parameters (step length, width, angle), and extracts gait health indicators (cadence/walking speed, left-right symmetry, gait balance, initial contact type).

Abstract: A measurement processing terminal includes: an imaging data collector that collects imaging data obtained by capturing a motion of a finger of a subject; a hand tracking data generator that implements a hand tracking function of detecting and tracking a position of the finger on the basis of the imaging data and generates chronological hand tracking data by the hand tracking function from the imaging data; and a data processor that processes the hand tracking data obtained from the hand tracking data generator to generate quantitative data regarding the bending/stretching motion of the finger and/or the opening/closing motion of two fingers accompanying the motion of the finger joint, and processes the hand tracking data, distance data and time data obtained from a movement distance measuring instrument, and line-of-sight data obtained from a gaze detector to generate correlation data obtained by quantifying a correlation between these data.

Abstract: A liquid metal (LM) sensor is provided herein. In certain embodiments, the LM sensor includes a wire. In certain embodiments, the wire includes a LM composite material. In certain embodiments, the LM composite material includes a LM material and a nonconductive material.