Abstract: Delivery devices for delivering a cardiac prosthesis to a target site are disclosed. Such devices can be used with a feedback system including haptic elements incorporated into the delivery device for providing tactile and/or audio feedback regarding the loading and/or deployment of the prosthesis. Certain disclosed delivery devices include a handle including an actuator, a sheath interconnected to the handle for selectively sheathing the prosthesis. The feedback system can be provided within the handle and configured to provide one or more feedback indications relating to the position of the sheath with respect to the prosthesis during loading and/or deployment of the prosthesis.

Abstract: Methods and apparatuses for regulating aortic regurgitation are provided. A catheter shaft is advanced through vasculature so that a flexible occluding membrane coupled to the catheter shaft is positioned within the aorta, typically the ascending aorta above the Sinus of Valsalva and coronary ostia. Blood flow in the aorta causes the flexible occluding membrane to alternate between an expanded occluding configuration while in diastole and a collapsed lesser occluding configuration is systole. The flexible occluding membrane thereby acts as a temporary aortic valve. The flexible occluding membrane is generally conical in shape, with the tip of the cone disposed closer to the aorta than the proximal rim. In diastole, blood flow expands the flexible occluding membrane so that the proximal rim apposes the inner wall of the aorta. The flexible occluding membrane will have one or more openings to allow perfusion of the coronary arteries in diastole.

Abstract: A prosthetic heart valve delivery system may include a handle, an outer catheter extending distally from the handle, and a balloon mounted to a distal end portion of the outer catheter. A prosthetic heart valve may be configured to be received over the balloon, and a balloon inflation system may be configured to inflate and deflate the balloon. The balloon may include a proximal balloon segment and a distal balloon segment positioned distal to the proximal balloon segment. An interior volume of the proximal balloon segment may be fluidly isolated from an interior volume of the distal balloon segment so that the proximal balloon segment and the distal balloon segment may be inflated independently of each other.

Abstract: A spacer instrument for use in a knee arthroplasty procedure includes a spacer carrier device with at least a first spacer component having a first thickness and a second spacer component having a second thickness. The first thickness is different than the second thickness. A rotative tibia component is rotatively attached to the spacer carrier device via a rotation mechanism. The rotative tibia component is movable in at least a first position and a second position. In the first position, the first spacer component is aligned above the rotative tibia component. In the second position, the second spacer component is aligned above the rotative tibia component, such that each of the spacer components can be 10 temporarily positioned on top of the resected proximal portion of a tibia with or without the rotative tibia component.

Abstract: A baseplate configured to mount on a surface of a glenoid and couple with a glenosphere for a reverse shoulder arthroplasty. The baseplate optionally comprising: a main body having a plurality of thru holes therein; and one or more wings coupled to the main body and extending outward therefrom, wherein the one or more wings include, at least one thru hole therein, and wherein the one or more wings are configured to be moveable relative to the main body to interface with the surface of the glenoid.

Abstract: A component including: a body having one or more surfaces with a contour formed to be substantially complementary to an anatomical surface of a specific patient; the body adapted to securably engage with a component-engaging part to form at least part of an implantable medical device, wherein: the one or more surfaces are substantially configured to evenly engage with the anatomical surface of the specific patient when the component is secured to the component-engaging part and the medical device implanted in the patient; and the body is at least in part manufactured by additive manufacturing.

Abstract: A spinal implant device comprises a first plate configured to be disposed in proximity to a first vertebral body; a second plate configured to be disposed in proximity to a second vertebral body, the second vertebral body opposing the first vertebral body; and a lattice structure disposed between the first plate and the second plate, the lattice structure configured to adjust an instantaneous axis of rotation between the first plate and the second plate during relative movement of the first plate and the second plate.

Abstract: An implant assembly for stabilizing a joint between a superior vertebra and an inferior vertebra may include a bone plate and an interbody spacer. The bone plate may include an anterior member having at least one superior fastener aperture and at least one inferior fastener aperture formed therethrough. The bone plate may also include a first arm extending from a first end of the anterior member, and a second arm extending from a second end of the anterior member, opposite the first arm, forming a cavity therebetween. The interbody spacer may be configured for placement within the cavity of the bone plate. At least a portion of the bone plate may be formed via at least one subtractive manufacturing process, and at least a portion of the interbody spacer may be formed via at least one additive manufacturing process.

Abstract: A positioning system for vertebral stabilization includes a holder, a vertebral stabilization plate, and an intervertebral cage. The components feature compatible diameters and locking mechanisms, enabling secure engagement of vertebral elements during surgery.

Abstract: A vertebral body replacement system having a quick-connecting removable endplate connection mechanism.

Abstract: A bone graft delivery system can include an elongate tube and a handle having a trigger and a ratcheting mechanism. The trigger is actuated to deliver bone graft material through the tube. The bone graft delivery system can further include a distal tip at a distal end of the tube. The tip has one or more openings to deliver the bone graft material to a desired location and includes a surface suitable to act as a rasp for decorticating bone. A method for delivering bone graft material to a desired surgical location includes providing a bone graft delivery device, positioning the device adjacent the surgical location, decorticating bone, and delivering bone graft material to the surgical location.

Abstract: A device for introducing an implant (1) into blood vessels or hollow organs of the human or animal body. The device includes an implant (1), an insertion wire (14) and a release tube (13), wherein the implant (1) is deformable so that it fits into a microcatheter (8) and expands once the external constraint of the microcatheter (8) disappears, adapting to the diameter of the blood vessel or hollow organ, wherein a holding element (2) is arranged on the insertion wire (14) and the holding element (2) has at its periphery at least one groove (3) set into the holding element (2), running along the circumference of the holding element (2) and forming tracks in the form of curved lines, wherein the implant (1) has holding wired (5) extending proximally, which are fitted into the grooves (3).

Abstract: An apparatus and method for aligning an acetabular cup. The apparatus may include an acetabular cup and/or a protractor and/or a depth gauge tool and may be provided in the form of a surgical kit. Components of the apparatus may allow an angle of rotation of an acetabular cup about an axis of the cup relative to an anatomical feature of a patient to be determined when the acetabular cup implant is placed in the acetabulum of the patient. Components of the apparatus may allow an amount of overhang between a rim of an acetabular cup and an edge of the acetabulum to be determined. The acetabular cup may be an acetabular trial cup or and acetabular cup implant. Embodiments of the invention may allow both the angle of rotation about the cup axis and the amount of overhang between the rim and the acetabulum edge to be determined.

Abstract: A drill guide for separation a bearing from a tray of an implant assembly can include a body, a collar, a first projection, a second projection, and a third projection. The body can be engageable with the bearing. The collar can be connected to the body and can define a guide bore configured to guide a drill bit into the bearing when the drill guide is engaged with the bearing. The first projection and the second projection can be engageable with a radially outer surface of the bearing. The third projection can be configured to engage an articulation surface of the bearing to, together with the first projection and the second projection, position the guide bore along a trajectory to guide the drill bit to form a hole in the bearing between the articulation surface and the tray when the bearing is connected to the tray.

Abstract: A femoral offset system for use in a knee arthroplasty procedure, in particular a revision procedure, includes a femur component connectable to a distal portion of a femur, and a femoral offset instrument connectable to the femur component. The femoral offset instrument includes a femur support connectable to the femur component via a connection mechanism.

Abstract: A prosthetic foot includes a base spring, a top spring assembly, a connector assembly, and a heel cushion. The top spring assembly includes first and second spring members, and first and second bond connections. The second spring member extends parallel with and spaced apart from the first spring member. The first bond connection is between distal ends of the first and second spring members, and the second bond connection is between a distal end of the second spring member and a top surface of the base spring. The top spring assembly has a first portion arranged horizontally, and a second portion arranged vertically. The connector is connected to a proximal end of the top spring assembly to connect the prosthetic foot to a lower limb prosthesis. The heel cushion is mounted to the base spring at a location spaced forward of a heel end of the base spring.

Abstract: Disclosed herein is a robotic ankle foot prosthesis that replicates the key biomechanical functions of the biological ankle and toe joints while matching the weight, size, and battery life of passive microprocessor-controlled prostheses. A single actuator powers the ankle and toe joints. The mechanism maximizes the mechanical energy regeneration during walking while imitating the physiological features of energy injection by way of the ankle joint and energy dissipation by way of the toe joint.

Abstract: A computer implemented method of classifying brain activity signals includes: receiving, as input to a neural network, input data comprising a plurality of brain activity signals; applying a first block to the input data to generate a plurality of first order wavelet scalograms, wherein the first convolutional block is configured to apply a plurality of Gabor filters to each of the plurality of brain activity signals, wherein each Gabor filter is associated with a learned bandwidth and learned frequency; applying one or more further blocks to the plurality of first order wavelet scalograms to generate a plurality of feature maps, wherein each further block comprises one or more convolutional layers; and applying a classification block to the plurality of feature maps, wherein the classification block is configured to generate one or more classifications of the plurality of brain activity signals from the plurality of feature maps.

Abstract: A prosthesis liner provided for fitting over a stump of a limb. The prosthesis liner includes a main body having an inner face directed towards the skin of the stump, and an outer face directed away from the stump. The prosthesis liner also includes a proximal access opening and a side wall, which extends from the access opening as far as a closed distal end portion of the liner. At least one sealing lip is arranged on the outer face of the main body and protrudes radially outwards from the main body.

Abstract: A stent for a respiratory organ, the stent having an inside surface and an outside surface, includes a base member and a hydrophilic polymer layer. The hydrophilic polymer layer contains a hydrophilic polymer having a hydroxy group and an amide group. The hydrophilic polymer layer is provided on at least a part of the inside surface and/or on at least a part of the outside surface.

Abstract: Stents described herein can comprise a tubular body having a midbody that extends to a first end and also extends to an opposing second end. The midbody can include a helical thread arranged along at least a portion of its length. The helical thread includes a plurality of turns with an interthread space disposed between the turns. The stent is formed from a plurality of wires woven or braided to form a mesh structure and a twisted wire structure. The twisted wire structure includes one or more pairs of wires longitudinally twisted together. The twisted wire structure can be disposed at one or more of the interthread space, the first end, and the second end.

Abstract: A guide tube (220) has a guidewire-engaging portion (222) at a distal portion (260) thereof, a first stent (54) surrounding the guide tube, advanceable together with the guide tube into a subject's lumen, a guidewire (12) arranged (i) entering the guide tube from a distal-end (320) opening thereof, (ii) disposed in the guidewire-engaging portion, and (iii) passing out of the guide tube proximally to the guidewire-engaging portion, and a second stent (54), proximal to the first stent, surrounding a proximal portion (240) of the guide tube and the guidewire. The first stent is slidably deployable off the distal end of the guide tube upon the guidewire having laterally exited the guidewire-engaging portion, and the second stent is slidably deployable off the distal end of the guide tube subsequently to deployment of the first stent, without the guidewire having been moved proximally. Other applications are also described.

Abstract: A system used to deploy an intraluminal device to the cardiac region of the stomach, wherein the intraluminal device has a wall defining a surface and an open portion of the surface that is adapted to be aligned with the gastroesophageal (GE) junction. The surface and the cardiac portion of the stomach are conformable with each other. The method includes deploying the intraluminal device trans-orally to the stomach with an endoscopic deployment device and retaining the device against the cardiac region of the stomach with the open portion generally aligned with the GE junction. The intraluminal device is fastened to the stomach from the abdominal cavity with at least one laparoscopic instrument while concurrently visualizing the device with an endoscope in the stomach while it is being fastened.

Abstract: A system that is adapted to deploy an intraluminal device to the stomach includes an endoscope that is adapted to visualize the intraluminal device in the stomach while the intraluminal device is being fastened to the cardiac portion of the stomach. An endoscopic deployment device that is adapted to deploying the intraluminal device trans-orally to the stomach includes the endoscope with the intraluminal device positioned at an exterior surface of said endoscope. The intraluminal device includes a self-expandable wall. The self-expandable wall is compressed to the endoscope shaft including a compression device adapted to maintain the wall compressed to said endoscope and a deploying filament adapted to extend external the patient. The deploying filament is adapted to release the compression device to allow the intraluminal device to self-expand in the patient's stomach.

Abstract: A kit for use with an endoscope having a shaft that is adapted to convert the endoscope into a combination endoscope and intraluminal device release device. The kit includes a holder having an inner diameter opening that is larger than an outer diameter of the shaft of the endoscope. An intraluminal device having a self-expandable wall is positioned on the holder. A compression device compresses the self-expandable wall to a compressed state. A deploying filament is configured to extend external the patient in order to release the compression device from the compressed intraluminal device to thereby allow the intraluminal device to self-expand to a deployed state.

Abstract: The present invention relates to orthopaedic products, in particular orthoses and support devices for orthoses. The invention provides an improved support device for an orthosis, a method of producing the same and an orthosis containing a support device according to the invention.

Abstract: A novel temporary knee-splint is disclosed herein. The invention provides an apparatus to immobilize a knee joint following an acute injury in order to maintain the stability of the knee. The knee-splint allows for a variable angle of knee flexion in order to increase comfort. The preferred embodiment of the knee-splint is formed from a thermoplastic polymer and is secured when in use via straps having a hook and loop arrangement. Anchor bars, also secured by the same straps, are used to maintain the desired angle of knee flexion when in use.

Abstract: A piece of lingerie. The piece of lingerie can include a main body of the piece of lingerie, and at least one binding strap fixedly or removably coupled to the main body. When the lingerie is worn on a body of a wearer, the binding strap can include a tension anchor proximate to the body of the wearer and at least one free binding end extending distally from the tension anchor. The binding end can be connected to the main body of the piece of lingerie at or via the tension anchor. The tension anchor can be disposed at or proximate a specific anatomical location on the body of the wearer, and the binding end of the binding strap can have a length sufficient to bind at least one limb of the wearer to said limb or to another limb of the wearer.

Abstract: A method of monitoring performance of an ostomy device includes monitoring moisture information with a monitor device attachable to a sensor and transferring the moisture information from the monitor device to an accessory device.

Abstract: A sensor patch for attachment to the adhesive surface of a base plate of an ostomy appliance is disclosed. The sensor patch has a proximal surface for attachment to the skin surface of a user and a distal surface for attachment of the sensor patch to the adhesive surface of a base plate. The sensor patch comprises an adhesive layer having a proximal side including a proximal surface for adhering the sensor patch to the skin, and a distal side including a distal surface; and a sensing layer comprising a nonwoven substrate and electrical conductors, the sensing layer arranged on the distal side of the adhesive layer, the sensing layer having a proximal side including a proximal surface and a distal side including a distal surface, the sensing layer being liquid permeable.

Abstract: An ostomy pouch having a cavity for storing stomal output. The cavity is defined by a rear wall and a front wall joined at their peripheries and formed of flexible sheet material. The ostomy pouch further comprises a sheet of woven comfort material covering the outside surface of the front wall. The sheet of comfort material has an outside surface and an opposite inside surface, and the outside surface of the sheet of comfort material forms at least part of the outside surface of the pouch. The inside surface of the sheet of comfort material is laminated across its entire surface to a continuous layer of film material. At least part of the continuous layer of film material is adjacent, facing and unbonded to the outside surface of the front wall.

Abstract: An example fluid collection assembly includes a fluid impermeable barrier. The fluid impermeable barrier at least defines a chamber, at least one opening. and a fluid outlet. The fluid collection assembly also includes at least one porous material disposed in the chamber. The porous material includes at least one of a polyurethane foam or a polyethylene foam. In an example, the porous material includes an outer layer disposed on an inner layer, wherein the outer layer includes the polyurethane foam and the inner layer includes the polyethylene foam.

Abstract: A palm cooling assembly for cooling a device used to lower a body temperature of a user includes a housing having a base wall and a peripheral wall. The peripheral wall is attached to and extends upwardly from the base wall defining an interior area. The peripheral wall has an upper edge defining an opening into the interior area. A panel is coupled to the upper edge and extends across the opening to enclose the interior area. The panel has a well therein. A palm cooling object is removably positionable in the well. The palm cooling object has a shape that is configured to at least partially cover a palm of a hand of a user who is gripping the palm cooling object. A refrigeration system controls a temperature of the interior area whereby the palm cooling object is cooled to the temperature when positioned in the well.

Abstract: Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

Abstract: Methods of hyperthermic treatment, including heating a tissue to a temperature range of 40° C. to 45° C., and exposing the heated tissue to a magnetic field having a field strength that is capable of extending the lifetime of a free radical entity within the heated tissue. The prolonged lifetime of the free radical entity in the heated tissue enhances the therapeutic effects of the treatment, leading to improved outcomes in various medical applications.

Abstract: Methods and systems for generating sterile cold solution are provided. The cold solution may be injected into subcutaneous fat of a subject to facilitate weight reduction or improve cosmetic appearances. The systems include a repository for receiving a solution, a generator for generating the cold solution from the solution, and a port for transferring the cold solution from the system. The generator includes a cooling device, a heat exchanger, and a recirculating fluid path configured to circulate a fluid which may include air. The methods include receiving a solution in the system, generating the cold solution from the solution, and transferring the cold solution from the system, wherein generating the cold solution includes circulating a fluid which may include air.

Abstract: Disclosed herein are systems, methods, and apparatuses for obtaining temperature data from a temperature sensing medical instrument. The targeted temperature management (TTM) system includes a TTM module configured to provide a TTM fluid, a thermal pad configured to receive the TTM fluid from the TTM module to facilitate thermal energy transfer between the TTM fluid and a patient, a fluid delivery line (FDL) extending between the TTM module and the thermal pad, the FDL configured to provide TTM fluid flow between the TTM module and the thermal pad, and a temperature sensing medical instrument configured to be inserted into the patient and obtain temperature data indicating a temperature of blood of the patient, wherein the temperature sensing medical instrument is further configured to communicatively couple to the TTM module and provide the TTM module with temperature feedback including the temperature of the blood of the patient.

Abstract: A surface and accessory system for temperature regulation and microclimate management of a patient includes a surface assembly including an outer covering and a spacer material. A pneumatic assembly is in fluid communication with the interior. The pneumatic assembly includes a housing. A blower is disposed within the housing. A flow rate valve is operably coupled to the discharge outlet of the blower. The flow rate valve is configured to adjust a discharge flow rate of the blower. A controller is communicatively coupled to the blower and the flow rate valve. The controller is configured to adjust at least one of an operating speed of the blower and a restriction setting of the flow rate valve to selectively generate a cooling effect and a heating effect with airflow directed by the blower through the surface assembly.

Abstract: An eye dropper with sensors that allows for delivery of a specific or controlled dose of a therapeutic agent in vapor form to a patient's eye is provided.

Abstract: Described are implantable devices having reservoirs for the sustained release of therapeutic agents. The devices are configured to be at least partially implanted in an eye and include a retention structure and a penetrable element coupled to and extending within at least a portion of the proximal end region of the device. The device includes a porous drug release element is positioned in fluid communication with an outlet of the device and a reservoir having a volume configured to contain one or more therapeutic agents in fluid communication with the outlet through the porous drug release element. The device is at least partially inserted along an axis of insertion.

Abstract: The present invention discloses a double-head separator for peripheral anterior synechiae, including a first head portion, a first neck portion, a handle portion, a second neck portion and a second head portion which are sequentially connected. At least one of the first neck portion and the second neck portion is designed in an elongated shape or designed in a bent structure, at least one of the first head portion and second head portion is provided with an arc-shaped ring in a longitudinal direction substantially perpendicular to the handle portion, and the arc-shaped ring of the first head portion or the second head portion is provided with a plurality of teeth. The separator of the present invention is applicable to various surgery for angle-closure and adherent glaucoma.

Abstract: The present invention discloses a knife for GT, including a handle portion, at least one end of the handle portion being sequentially connected to a neck portion and a head portion, wherein the neck portion is smoothly transited to the head portion and formed an angle of 85-95 degrees therebetween, the head portion has a blunt tip end, and a diameter of the head portion is decreased towards the blunt tip end to form a knife face. The knife of the present invention is convenient to use and easy to operate, more conforming to the requirements of the ergonomics, and thus achieves improved operation efficiency.

Abstract: The present disclosure provides generally for a therapeutic recovery device for medical rehabilitation and travel. The therapeutic recovery device may comprise a compression device. The compression device may provide compressive force that provides relief and comfort during travel. The therapeutic recovery device may comprise at least one securing mechanism. The therapeutic recovery device may comprise one or more straps. The one or more straps may allow the therapeutic recovery device to be secured in a plurality of orientations. The therapeutic recovery device may comprise at least one holder. When the therapeutic recovery device comprises at least one holder, the holder may comprise one or more pockets.

Abstract: A method for folding absorbent sanitary articles, wherein a plurality of absorbent sanitary articles advancing at a first speed are alternately routed towards at least two folding lines, are slowed down to a second speed less than the first speed, are folded while advancing at the second speed, and are fed aligned with each other in a common outlet array.

Abstract: A multi-layered material, in particular for hygiene/sanitary products, has an outer surface shaped so as to have a plurality of recessed areas and at least one embossed area which is arranged alongside the recessed areas and protrudes with respect to the recessed areas so as to define a thickness greater than the one at the recessed areas; each of the recessed areas has a plurality of through holes; the multi-layered material has a first and a second layer, whereby the through holes pass through both said layers; the second layer is a non-woven fabric, while the first layer defines the outer surface of the multi-layered material and is a plastic film having a plurality of protruding micro-portions that are provided at least at the embossed area and protrude outwards from the remaining part of the first layer along said outer surface.

Abstract: An absorbent article includes a liquid pervious topsheet, a backsheet at least peripherally joined to the topsheet, and an absorbent core disposed between said topsheet and said backsheet. The absorbent article further includes an integrated nonwoven fluid management layer having a basis weight between about 40 gsm and about 65 gsm; and an Urine Standard Rewet Value of 10 mg or less.

Abstract: A closing element for producing reclosable absorbent sanitary articles includes a non-woven sheet folded according to a general omega-shaped configuration and including a base, two intermediate flaps connected to respective ends of the base by respective first folds, and two distal flaps connected to respective ends of the respective intermediate flaps by respective second folds, wherein the base has a dimension between 15 and 90 mm and each of the intermediate flaps has a dimension between 5 and 30 mm.

Abstract: The invention concerns a device for assisting in loading (1) a stretcher (2) on board a vehicle, said stretcher (2) extending longitudinally between a first and a second end, said device (1) comprising at least: a substantially elongated and tiltable guide means between a substantially horizontal position and an inclined position, a first support element designed to receive said stretcher (2) towards said first end, said first support element being mounted in translation relative to said guide means so that in the inclined position, said first support element can pass from a high position to a low position. Loading assistance devices of stretchers on board vehicles.

Abstract: To provide access to individuals having mobility disabilities, an OEM battery electric vehicle may be modified to include one or more of a wheelchair ramp, a lowered floor, a lowered battery, an adjustable suspension, and supplemental impact protection. The adjustable suspension of the modified vehicle may be operated to position the body of the vehicle alternatively between a lowered position and a raised position. In the lowered position, at least one of the ramp angle and length may be reduced relative to a comparable ramp in the OEM vehicle. In the raised position, the vehicle ground clearance may be slightly less than, approximately equal to or greater than the ground clearance of the OEM vehicle at GVWR.

Abstract: A self-locking wheelchair device is disclosed that automatically brakes the wheel when the wheelchair is parked so patients don't have to worry about the wheelchair moving when they get out of the chair. The self-locking wheelchair device comprises a pressure sensitive pad that is configured in a rectangular shape and positioned in a seat of a conventional wheelchair. The pressure sensitive pad is in communication with a control box comprising a battery, a controller, and a motor. The control box is then in communication with at least one automatic brake assembly, such that when a user attempts to stand from a wheelchair, the brakes are automatically engaged. The device also includes a manual brake to override the automatic brake assemblies, as needed and a lock/release lever once the user has risen or been seated within the wheelchair, to disengage the automatic brake assemblies.