Abstract: Devices, systems and methods are disclosed for measurement and reduction or prevention of fluid movement in lactiferous ducts, detection of diseased conditions in the breasts, and treatments thereof. Such techniques, methods and devices are applicable to a variety of conditions including carcinomas.

Abstract: A device for treating fecal incontinence in a subject is provided. The device includes a plug configured for positioning mostly within an anal canal of the subject.

Abstract: A method and device may be used to avoid surgically re-opening a stoma or the like in an animal, including human beings. The stoma stabilitating device comprises an anchoring portion, preferably flat, that includes an opening configured to surround a stoma. The anchoring portion preferably includes an inner tension ring attached to an inner edge to define the opening and a tension ring attached to an outer edge. The anchoring portion may include additional structural rings. The device may be of a mesh construction and used to maintain, for example, a stoma, a fistula, a tracheotomy and any other pathway from outside the body to the inner part of the body. The device may be used to maintain an open pathway for air and to maneuver devices within a cavity. The device may also be used internally.

Abstract: A device for treating fecal incontinence in a subject is provided. The device includes a plug configured for positioning mostly within an anal canal of the subject.

Abstract: A cylindrical plug for insertion through the punctum and into the canaliculus to block the flow of tears therethrough comprises an insert of a material which when hydrated expands and changes shape, conforming at least to a portion of the canaliculus crossection and contacting the walls of the canaliculus, thus blocking flow. The plug can be inserted in a dry state and hydrating in situ or hydrated, either partially or fully, prior to insertion.

Abstract: A device for treating fecal incontinence in a subject is provided. The device includes a plug configured for positioning mostly within an anal canal of the subject.

Abstract: Punctal plugs for delivering therapeutic agents to the eye have a body with a portion into which the therapeutic agent is loaded and a conical anchor portion at an end of the plug.

Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.

Abstract: Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.

Abstract: A punctal plug is disclosed, wherein the punctal plug includes a body portion and a retaining portion. The body portion is defined by an open distal end, an open proximal end and a wall portion. The wall portion further includes at least one window extending therethrough. The retaining flange is configured to have an outer periphery that is larger than the outer periphery of the body portion. A method of delivering a therapeutic agent to a patient using a punctal plug is also disclosed.

Abstract: A device for occluding the fallopian tube having a wire composed of a shape memory material and an outer material encapsulating at least a portion of the wire. The device has a first elongated configuration for delivery and a second configuration for placement. In the second configuration, the wire moves toward its shape memory position and has a U-shape defined by a curved portion and first and second leg portions extending from the curved portion, the first and second leg portions extending downwardly from the curved portion and laterally outwardly.

Abstract: A multi-piece punctal plug has one or more superficial plugs connected to an anchor plug deeper in the naso-lacrimal canaliculus. The anchor is fixed to the wall of the lacrimal duct while the superficial plugs are axially and detachably secured to the anchor plug so that the multi-plug complex may be inserted or removed together as one, or the superficial plugs may be detached separately and replaced securely without disturbing the anchor. Removal and insertion is accomplished by a specific tool having an end for engaging the plugs.

Abstract: Monocanaliculonasal and/or monocanalicular intubation assembly mainly intended for nasolachrymal imperforation, comprising a mandrel (2) made of a first substantially rigid material, such as a metal, and a tube (1) made of a second material that is less rigid than the first material and essentially flexible, such as silicone, a blocking plug (6) for locking the tube in position in the lachrymal duct and protruding laterally from the tube, characterized in that the length of the tube (1) is smaller than the length of the mandrel (2) and the mandrel (2) has a greater thickness, measured in a direction perpendicular to the longitudinal direction, relative to that of the tube (1), such that said mandrel can be inserted inside the tube and withdrawn therefrom.

Abstract: The invention provides intrafallopian devices and non-surgical methods for their placement to prevent conception. The efficacy of the device is enhanced by forming the structure at least in part from copper or copper alloy. The device is anchored within the fallopian tube by a lumen-traversing region of the resilient structure which has helical outer surface, together with a portion of the resilient structure which is biased to form a bent secondary shape, the secondary shape having a larger cross-section than the fallopian tube. The resilient structure is restrained in a straight configuration and transcervically inserted within the fallopian tube, where it is released. Optionally, permanent sterilization s effected by passing a current through there resilisent structure to the tubal walls.

Abstract: A punctal plug is disclosed, wherein the punctal plug includes a body portion and a retaining portion. The body portion is defined by an open distal end, an open proximal end and a wall portion. The wall portion further includes at least one window extending therethrough. The retaining flange is configured to have an outer periphery that is larger than the outer periphery of the body portion. A method of delivering a therapeutic agent to a patient using a punctal plug is also disclosed.

Abstract: The invention provides intrafallopian devices and non-surgical methods for their placement to prevent conception. The efficacy of the device is enhanced by forming the structure at least in part from copper or copper alloy. The device is anchored within the fallopian tube by a lumen-traversing region of the resilient structure which has helical outer surface, together with a portion of the resilient structure which is biased to form a bent secondary shape, the secondary shape having a larger cross-section than the fallopian tube. The resilient structure is restrained in a straight configuration and transcervically inserted within the fallopian tube, where it is released. Optionally, permanent sterilization s effected by passing a current through there resilisent structure to the tubal walls.

Abstract: A medical dressing for chest wounds, including a one-way valve that can be covered so as to protect against intrusion of airborne contaminants and to prevent passage of fluids in either direction, and including indicia visible using night vision devices but not visible in visible light to the naked eye in some embodiments. The indicia visible using night vision devices may be included in other medical apparatus, as well, so that the medical dressings or other apparatus can be used effectively during darkness, in combat situations, without being seen by enemy combatants not equipped with night vision devices.

Abstract: A body portion fabricated of an essentially rigid material is formed of similarly configured first and second segments each shaped to include a generally spherical interior enlargement, a generally spherical exterior enlargement, an intermediate section between the enlargements, and a slit extending through the exterior enlargement and the intermediate section. The body portion pivots between a collapsed orientation with the slit at a reduced spacing and an expanded orientation with the slit at an enlarged spacing. An operational zone has a plurality of operational components. Application of a radial force to the second section by a user's external anal sphincter muscle causes axial movement of the segments to both contract and retain expanded segments and expand and retain contracted segments to reorient the system between a collapsed orientation and an expanded orientation.

Abstract: A flexible membrane is situated within a rigid or semi-rigid cap. The edge of the cap wall is adhesively fixed to the tissue surrounding the stoma. The interior of the cap is pressurized to press the membrane to seal the stoma against the discharge of solid and semi-solid waste. Gas escapes through a vent with a filter element. The cap can be pressurized by an external pump or an integral pump member situated on top of the cap. A relief valve prevents over pressurization. A collection pouch can be provided as part of a device. The device can be removably mounted on a standard two-piece faceplate.

Abstract: A flexible membrane is situated within a rigid or semi-rigid cap. The edge of the cap wall is adhesively fixed to the tissue surrounding the stoma. The interior of the cap is pressurized to press the membrane to seal the stoma against the discharge of solid and semi-solid waste. Gas escapes through a vent with a filter element. The cap can be pressurized by an external pump or an integral pump member situated on top of the cap. A relief valve prevents over pressurization. A collection pouch can be provided as part of a device. The device can be removably mounted on a standard two-piece faceplate.

Abstract: A dressing able to adhere to the skin and/or a wound for covering a portion of the anatomical surface of a living being and demonstrating considerably increased wearing time. The dressing has a backing layer and a layer of skin-friendly adhesive for adhering to the skin, and includes a pattern of connected indentations formed in a pattern that is not linear and which progresses in at least three main directions.

Abstract: A controlled evacuation ostomy appliance comprises a membrane that is urged into sealing engagement with a stoma, by the generation of radial tension in the membrane. A tensioning device applies tension, with respect to the stoma, at one or more positions that are (i) outboard of the periphery of the projecting portion of the stoma, and/or (ii) between the level of the peristomal skin and the level of the most projecting part of the stoma. Tension limiting means are disclosed. The membrane may be gas-permeable to allow flatus to be vented.

Abstract: A perianal support device is provided that is configured to inhibit the formation and/or progression of tissue damage in the perianal region of the body. A method is provided to apply the perianal support device to patients during childbirth to inhibit the formation and/or progression of tissue damage in the perianal region of the body.

Abstract: An protective device for insertion into the crevice adjacent to the anus, and cover adjacent portions of the derriere. The protective device cover includes a solid sheet of material with an adhesive on one side which adhesive can be used to apply the cover directly onto the portion directly around and adjacent to the anus after it has been inserted into the crevice. The cover also includes slits or holes through which evacuated material may pass through. The cover may also be made from a “plastic-wrap” type material that adheres to human skin when pressure is applied. In an alternate embodiment, a wiping pad is provided between two layers of the cover, which traverses the hole opening when a stab string is pulled to effect at least partial cleaning in the anus area. This almost eliminates the need for toilet paper, keeps the body clean, and avoids excessive contamination.

Abstract: A device for occluding the fallopian tube including a retention member and a mesh material supported by the retention member. The retention member has a first lower profile configuration for delivery and a second expanded configuration for placement within the fallopian tube. The mesh material is configured to block passage of an egg through the tube. The member has a plurality of tube engagement members to secure the retention member to the fallopian tube.

Abstract: The invention relates to an appliance for irrigation and/or drainage, which appliance comprising a body side member comprising an adhesive wafer for securing the appliance to the patient's skin, said wafer can be provided with an aperture for receiving a stoma, surrounding a wound, a fistula or a drainage site, a wall of flexible material, the wall comprising a rear wall and a front wall, the rear wall being attached to the wafer and having an opening suitable for surrounding the surface area of the skin to be cleansed, and the front wall comprising a coupling flange adapted for removable coupling and sealing to matching coupling means, an sealed chamber which, when inflated, provides a distance between the adhesive wafer and the coupling flange.

Abstract: Methods and devices provide for temporary partial aortic occlusion to achieve diversion of blood flow to the brain in patients suffering from cerebral ischemia. The device can include an expandable frame with a membrane mounted on a first portion of the frame. The membrane can have at least one opening. In some embodiments, the membrane has an outer region and an inner region, and an opening in the inner region. In use, the frame can expand to conform to the inner walls of the aorta and the membrane can at least partially occlude the aorta thereby increasing cerebral perfusion. The frame can include one or more anchors to aid in maintaining the device in position against the arterial blood flow pressure.

Abstract: A biomaterial mass is inserted through a punctum into a canaliculus in the lacrimal outflow system with a syringe. The mass has an outer cross section that is less than the inner cross section of the canaliculus. The mass absorbs liquid to swell to form a lacrimal filler or sealing mechanism. The lacrimal filler has an external cross section that conforms to the internal cross section of the canaliculus and a soft outer surface relative to the surrounding tissues to prevent erosion of the canaliculus lining. The lacrimal filler forms an occlusion that prevents the outflow of liquid through the lacrimal outflow system to retain tears within the eye to maintain eye lubrication and wetness. The mass and syringe are provided in kit with a rubber stopper and, optionally, a punctal dilator, an injecting catheter, and an enzyme for dissolving or degrading the lacrimal filler at a later time.

Abstract: A punctum plug comprises a distal tip for anchoring the punctum plug in an implanted position in the lacrimal drainage system of the eye, a proximal cap that remains exposed in the eye in the implanted position, and a body connecting the distal tip to the cap. The distal tip includes a plurality of longitudinal depressions along its outer surface to facilitate implantation, and one or more strengthening beams to resist deformation or collapse of the punctum plug.

Abstract: A leak-resistant medical barrier is disclosed as having a sheet with a first side and a second side. The first side has an adhesive portion adapted to be disposed on a patient's skin and a release liner disposed on the adhesive portion. The second side also has an adhesive portion adapted to be disposed either on a patient's skin, on itself, or on a patient's skin and on itself and a release liner disposed on its adhesive portion. The second side adhesive portion is adapted such that when it is disposed on itself, it joins portions of surfaces of the medical barrier to form a leak-resistant seal between the surfaces, thereby providing for a medical barrier of adjustable volume and patient-adhesive contact area.

Abstract: Lacrimal implants and related methods providing secure, wedgable retention within a lacrimal punctum and associated canaliculus of an eye are disclosed. The lacrimal implants can comprise an implant body configured for at least partial insertion through the lacrimal punctum and into the canaliculus. The implant body can include first and second portions, and can extend from a proximal end of the first portion defining a longitudinal proximal axis to a distal end of the second portion defining a longitudinal distal axis. The implant body can be configured such that, when implanted using an integral dilator, an angled intersection exists between the proximal and distal axes. In this way, at least a portion of the implant body can be biased against at least a portion of the lacrimal canaliculus located at or more distal to a canalicular curvature, thereby retaining an implanted position of the lacrimal implant using anatomical structures.

Abstract: A punctal plug inserted into the punctum-canaliculus, includes a shaft, a tip portion attached to one end of said shaft and a brim attached to the other end of said shaft, and a thin member penetrated into either one or all 3 out of said tip portion, shaft and brim, or said tip portion and shaft, or said shaft and brim. The thin member is thread 0.05 mm or less in diameter. The brim is disk shaped and the diameter of the brim is far smaller than the diameter of the tip. A protuberance is attached to the tip portion.

Abstract: Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.

Abstract: A perianal support device is provided that is configured to inhibit the formation and/or progression of tissue damage in the perianal region of the body. A method is provided to apply the perianal support device to patients during childbirth to inhibit the formation and/or progression of tissue damage in the perianal region of the body.

Abstract: A perianal support device is provided that is configured to inhibit the formation and/or progression of tissue damage in the perianal region of the body. A method is provided to apply the perianal support device to patients during childbirth to inhibit the formation and/or progression of tissue damage in the perianal region of the body.

Abstract: The invention concerns lachrymal plugs, and methods for setting said devices. It concerns a lachrymal plug (10) designed to be inserted in the lachrymal canaliculi (5), said plug, optionally provided with an axial duct, comprising on its outer walls flexible elements (11) foldable on said walls to enable the plug to be inserted in the lachrymal duct and adapted to straighten up once the lachrymal plug is set, so as to maintain the latter in position. The invention generally concerns means for controlling the flow of tears running from the surface of the eye towards the nasal cavity.

Abstract: A device for containing emboli within a left atrial appendage of a patient includes a frame that is expandable from a reduced cross section to an enlarged cross section and a slider assembly. The frame extends between a proximal hub and a distal hub, and the slider assembly is coupled to the distal hub of the frame. The slider assembly includes a guide tube that has a channel extending proximally away from the distal hub, and a nut. The nut is longitudinally moveable within the channel of the guide tube over a predetermined distance relative to the guide tube. The nut is operable to be releasably coupled with an elongate core, and movement of the nut relative to the guide tube is at least partially limited by interference between a portion of the nut and a portion of the guide tube.

Abstract: An apparatus to protect a body and facial piercing and its affected area during a healing period, has a body assembly. The body assembly has top and bottom faces, an exterior wall, and an interior wall. The body assembly further defines a cavity that extends inwardly from the interior wall. A permeable cover covers the top face and the cavity to allow ambient-air to enter and circulate therethrough. This allows healing of a body or facial piercing, and specifically the opening created by the piercing, and the surrounding area around the piercing. A removable cover covers the bottom face and the cavity. The bottom face has an adhesive, and the removable cover is removably attached to the bottom face.

Abstract: Apparatus for preventing fluid transfer through an opening connecting an oviduct to a uterine cavity includes a body having a base with a periphery and a seal carried by the body for overlying and engaging uterine tissue leading to the opening. The seal receives fibroblast in-growth to create a hermetic seal between the oviduct and the uterine cavity. A peripheral anchor portion extends from the base for securing the body to the uterine tissue leading to the opening, the base overlying the opening.

Abstract: An obturator for a bronchial tube or tubule of a human or animal lung comprises a blocking element (92) and a securing element (90). The blocking element serves to seal the tube or tubule against the passage of fluid past the obturator when the obturator is disposed in a bronchial tube or tubule. The securing element serves to retain the blocking element in position. The blocking element comprises a substantially cylindrical plug of biocompatible, resiliently deformable closed-cell foamed plastics material, such as PVC. The securing element comprises a stent having barbs (98) to engage and retain the blocking element. The stent also has anchors (100) to retain the stent in a bronchial tube or tubule. A method of treatment of emphysema or other lung conditions or diseases in human or animal patients comprises placing an obturator in a bronchial tube or tubule of the patient so as to seal the tube or tubule against the passage of fluid past the obturator.

Abstract: Methods for diagnosis and treatment are provided for a patient having processing difficulties, integration problems, imbalances or abnormal postures. In one embodiment, a patient is identified having retinal signal problems creating at least one negative medical condition. Then, at least a portion of the patient's lacrimal drainage system is blocked or altered. Further, as a result of the diagnosis and treatment, the patient achieves improved retinal signal processing and at least one of the patient's negative medical conditions is improved. Other embodiments include using in combination the Z-Bell Test and/or light blocking or altering devices for diagnosis and treatment.

Abstract: Methods, systems and devices are provided for monitoring respiratory disorders based on monitored factors of a photoplethysmography (PPG) signal that is representative of peripheral blood volume. The monitored factors can be respiratory effort as well as respiratory rate and/or blood oxygen saturation level. The systems and devices may or may not be implanted in a patient.

Abstract: A perianal support device is provided that is configured to inhibit the formation and/or progression of tissue damage in the perianal region of the body. A method is provided to apply the perianal support device to patients during childbirth to inhibit the formation and/or progression of tissue damage in the perianal region of the body.

Abstract: A self-expanding medical occlusion device treats a heart defect in a patient and is inserted into the body in minimally invasive fashion using a catheter system, and includes a braiding of thin threads which exhibits a first preliminarily definable shape as the occlusion device is being inserted into the patient's body and a second preliminarily definable shape in the implanted state, whereby the occlusion device is in a collapsed state in the first shape of the braiding and in an expanded state in the second shape of the braiding. The threads of braiding are composed of a shape memory polymer composite such that braiding deforms from a temporary shape to a permanent shape in consequence of an external stimulus, whereby the temporary shape is given in a first profile form of the braiding and the permanent shape is given in a second profile form of the braiding.

Abstract: Occlusion devices and methods for occluding fallopian tubes which take effect promptly after deployment. The occlusion device comprises an occluding element and a fixation element. In one embodiment, the occluding element is deployed within the fallopian tube and in another embodiment, the occluding element is external to the fallopian tube.

Abstract: A method of facilitating hemostasis of a blood vessel puncture. The method includes the steps of inserting a tubular device into a puncture in a blood vessel to establish access to the blood vessel, providing a vessel closure system around the tubular device, introducing a hemostatic material into a space between the tubular device and vessel closure system, and delivering the hemostatic material adjacent to the puncture to facilitate hemostasis of the puncture.

Abstract: Embodiments of a chest dressing assembly having a rigid body defining an inner chamber accessible by an opening for placement over a chest wound and one or more protected check valves on the rigid body that allow fluid, e.g., blood or air, to flow out of the chamber but prevent fluid flow into the chamber are disclosed. The body is rigid in order to prevent the dressing from being crushed when heavy clothing such as body armor covers the dressing, or in cold weather climates which require heavy clothing such as Afghanistan. Similarly, the body is shaped and the check valves are located on the body, such as in a recess, in order to prevent the same heavy clothing or body armor from interfering with the operation of the check valves.

Abstract: A plug for the meatus of a lacrimal canaliculus, the plug including an elongate body (2, 12, 13) having a longitudinal axis (2a) and provided at one of its ends with a collar (1, 11) substantially perpendicular to the longitudinal axis, in which the elongate body (2, 12, 13) possesses a first portion (2, 12) adjacent to the collar (1, 11) of cross-section that is elliptical with a major axis, and a second portion (3, 4, 13) which extends the first portion (2) obliquely relative to its longitudinal axis (2a) in the plane of the above-mentioned major axis of the section of the first portion.

Abstract: A flexible sheet having an adhesive layer carried on a bottom side. A collection chamber formed in the adhesive layer by the exclusion of adhesive from a central area of the sheet for receiving fluid from the wound. A drainage channel formed in the adhesive layer by the exclusion of adhesive from a selected area of the sheet extending radially outward from the collection chamber to a drain outlet at a peripheral edge of the sheet to drain fluid from the collection chamber. The collection chamber and drainage channel having an open position allowing fluid to flow outward from the collection chamber through the drain outlet, and a closed position collapsed against the skin to prevent fluid intake through the drain outlet. A storage compartment carried by the flexible sheet including a needle and catheter for immediate access in treating a tension pneumothorax.

Abstract: An apparatus for inhibiting blood loss from a puncture site. The apparatus may include means for locating a puncture site in a blood vessel wall. This apparatus is comprised of a tube and an elongated member that is positioned around the tube. The elongated member includes a proximal end and a distal end. Around the tube is also a dissolvable distal capsule, the distal capsule including a proximal end and a distal end, wherein the proximal end of the distal capsule attaches to the distal end of the elongated member. Inside the distal capsule is hemostatic material such as a sponge.