Methods Patents (Class 128/898)
  • Patent number: 11364390
    Abstract: An electromagnetic field generating apparatus for treating pathological cells, in particular with tumor suppression function. The ratio of static magnetic field to alternating magnetic field is in the range of 0.5-2.5, and the total intensity is in the range up to 100 mT. It provides non-invasive low toxicity and side effects, significantly inhibiting a plurality of tumors, influencing the intracellular superoxide radical content, and promoting cell autophagy. The mechanism of action of the magnetic field is on the electron spin energy levels and consequently on free radical concentration. Additional magnetic field having frequency up to 100 MHz and intensity down to microTesla range can be also used to improve the antitumor efficacy in combination with the static as well as the extremely low frequency electromagnetic field (1-300 Hz) influencing the spin hyperfine resonance. A combination method is also provided of a power-frequency electromagnetic field generating device and a platinum-based medicine.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: June 21, 2022
    Inventors: Santi Tofani, Xi Chen, Linqing Yuan, Kexin Shi, Chao Yang, Suchen Bian, Jinhu Wang, Kun Zhu, Min Yang, Weizhong Gu, Shiqiang Shang, Huamei Li, Zheng Shen, Can Wang
  • Patent number: 11357508
    Abstract: A surgical stapling instrument includes an anvil assembly, a shell assembly, and an adapter assembly. The adapter assembly includes a tubular shaft supporting the shell assembly at a distal portion of the tubular shaft, and a trocar assembly transitionable between an extended configuration and a retracted configuration. The trocar assembly includes a trocar detachably supporting the anvil assembly thereon, a lead screw adapted to be coupled to an actuator for rotational input, a first member rotatably supporting the lead screw, a second member operatively coupled to the lead screw such that rotation of the lead screw causes axial displacement of the second member relative to the first member, and a light diffuser configured to scatter light received from a light source. The light diffuser is configured to be surrounded by the anvil center rod when the anvil center rod is attached to the trocar.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: June 14, 2022
    Assignee: Covidien LP
    Inventors: David E. Valentine, Joseph Eisinger
  • Patent number: 11361893
    Abstract: A soft body robotic device includes a body made at least partly from a polylactic-acid-based material, and a magnetic movement mechanism connected to the body. The magnetic movement mechanism is configured to support movement of the soft body robotic device and to interact with an external magnetic control device for movement of the soft body robotic device.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: June 14, 2022
    Assignee: City University of Hong Kong
    Inventors: Yajing Shen, Xiong Yang, Haojian Lu
  • Patent number: 11357667
    Abstract: A treatment device for the surgical correction of hyperopia in the eye comprising a laser device controlled by a control device. The laser device separating corneal tissue by applying laser radiation. The control device controls the laser device for emitting the laser radiation into the cornea such that a lenticule-shaped volume is isolated. Removal thereof effects the desired correction. The control device predefines the volume such that a posterior surface and an anterior surface are connected via an edge surface that has a width in projection along the visual axis that is wider than the one which a straight line in the same projection, that is perpendicular at the edge of the posterior or the anterior surface would have relative to the associated surface and connects the anterior surface to the posterior surface or to the perceived extension thereof.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: June 14, 2022
    Assignee: Carl Zeiss Meditec AG
    Inventors: Mark Bischoff, Gregor Stobrawa, Wilfried Bissmann
  • Patent number: 11350875
    Abstract: A wearable device may be provided for detecting cumulative alcohol consumption. Such a wearable device may include an adhesive layer that adheres to skin and that allows sweat from the skin to pass through and a customizable ink layer that reacts irreversibly to change color along a gradient as ethanol is detected in the sweat. The customizable ink continues to increase color intensity along the gradient as ethanol continues to be detected in the sweat over time.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: June 7, 2022
    Inventors: Tal Danino, Ian Fritz, Carlos Olguin, Skylar Tibbits, Marcelo Coelho
  • Patent number: 11344295
    Abstract: A minimally invasive surgical method of approximating tissue includes coupling an adjustable loop of suture around an inserter. The loop can be coupled to the inserter by applying tension to a tail of the suture to collapse the loop around the inserter, then the inserter and loop are passed through a first location in tissue. The loop is decoupled from the inserter, the inserter is retracted from the first location, and reinserted into a second location in the tissue, after which the loop is recoupled to the inserter while the loop is distal of the tissue. The decoupling, retraction, and reinsertion can occur without withdrawing the inserter from the patient's body. The inserter and loop are then withdrawn together from the tissue through this second location and outside of the patient's body. The tails and loop can form a luggage knot to be reduced around the tissue.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: May 31, 2022
    Inventor: Adam C. Gustafson
  • Patent number: 11337753
    Abstract: The disclosure provides various embodiments of systems to facilitate the cutting of luminal tissue structures percutaneously.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: May 24, 2022
    Assignees: Telltale LLC, The National Institutes of Health (NIH)
    Inventors: Nasser Rafiee, Robert J Lederman, Rany Busold, Morgan House, Jaffar Khan, Toby Rogers, Christopher G Bruce
  • Patent number: 11331139
    Abstract: Methods and devices are disclosed herein for therapeutically treating atrial tissue to lessen the effects of mechanical stress on atrial tissue, where reducing mechanical stress in the portion of atrial tissue reduces formation of at least one arrhythmia substrate. In one example, the devices and methods are suitable for minimally invasive surgery. More particularly, methods and devices described herein permit creating an ablation pattern on an organ while reducing excessive trauma to a patient.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: May 17, 2022
    Assignee: AtriCure, Inc.
    Inventors: James G. Whayne, Sidney D. Fleischman
  • Patent number: 11324587
    Abstract: A corneal implant and methods of forming and implanting the implant are described. The corneal implant comprises a portion of corneal endothelial tissue and a portion of scleral tissue. The corneal implant is keyhole shaped, with a disc portion and a tail portion. The tail portion may further comprise a perforated section.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: May 10, 2022
    Inventor: Chandrashekar Balachandran
  • Patent number: 11324424
    Abstract: In some embodiments, an apparatus for imaging blood within a target region of tissue includes an imaging device configured to output image data associated with light received by the imaging device having a first and second spectral ranges, wherein the absorptivity by blood of light having the first spectral range is less than the absorptivity by blood of light having the second spectral range, and a controlling element configured to capture the image data associated with light received by the imaging device and to process the captured image data associated with light having the first spectral range and the captured image data associated with light having the second spectral range to generate compound image data associated with an amount of blood within the target region of tissue.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: May 10, 2022
    Assignee: Smith & Nephew PLC
    Inventors: Scott Grubb, Allan Kenneth Frazer Grugeon Hunt, Peter Laitenberger
  • Patent number: 11324495
    Abstract: The present disclosure describes devices, systems, and methods for intravascularly delivering an implantable device at the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly. The intravascular device is attached at the distal end of the delivery member, and is housed within a distal piece of an outer sheath. A steering catheter is nested within the outer sheath to bend the delivery member into position. A delivery catheter is configured to advance the intravascular device relative to the outer sheath, and a suture catheter includes sutures/tethers which may be coupled to the intravascular device prior to deployment.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: May 10, 2022
    Inventors: Randolf von Oepen, Sean A. McNiven, Francisco Valencia
  • Patent number: 11324543
    Abstract: Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: May 10, 2022
    Assignee: Galvanize Therapeutics, Inc.
    Inventors: Jonathan Reuben Waldstreicher, William Sanford Krimsky, Denise M. Zarins, Robert J. Beetel, Paul Brian Friedrichs, Kevin James Taylor, Roman Turovskiy, Robert E. Neal, II
  • Patent number: 11322238
    Abstract: A computer-implemented medical device management method for distributing data sets to a plurality of medical devices in child locations of a parent health organization includes providing a first data set, receiving a first user input to distribute the first data set, distributing the first data set to medical devices located in child locations within the parent organization, and facilitating operation of the medical devices according to the first data set. The method also includes providing a second data set different from the first, receiving, after the first user input, a second user input to distribute the second data set to target medical devices, commencing distribution of the second data set prior to completing distribution of the first data set, and stopping distribution of the first data set for all medical devices that have not yet received the first data set and that are target medical devices.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: May 3, 2022
    Assignee: Fenwal, Inc.
    Inventors: Thomas Karakosta, Witold Moskal
  • Patent number: 11318282
    Abstract: A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: May 3, 2022
    Assignee: Route 92 Medical, Inc.
    Inventors: Michi E. Garrison, Tony M. Chou
  • Patent number: 11317952
    Abstract: An orthopedic plate has a first end including a locking screw hole that receives a locking screw and spaced from that hole is a closed compression housing that extends from the bone-facing side of the plate and which receives a compression screw that forms an angle of from about 10° to about 70° with a longitudinal axis of the plate. The compression housing is not located on the medial line of the plate, but is peripheral to the medial line, either in the longitudinal or the medial direction of the plate.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: May 3, 2022
    Inventors: Jackson R. Heavener, Jeffrey Johnson, David B. Kay
  • Patent number: 11311330
    Abstract: A portable electrocauter used especially for electrofulguration, electrodesiccation and electrocoagulation contains a source of energy and an applicator. The electrocauter is provided with the source of DC with the maximal current of 1 mA and voltage between 0.8 to 12 kV. The applicator is provided with precisely aiming finish and the patient is conductively connected with the equipment by disposable grounding electrode while the output of the discharge between the working electrode and the surface of the skin is in the range of 0.3 to 4.0 W.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: April 26, 2022
    Inventor: Radek Nespor
  • Patent number: 11304658
    Abstract: The method for diagnosing cerebrospinal fluid hypovolemia includes injecting saline into a subdural space of a subject in a decubitus position, raising an upper body of the subject, and then determining whether the subject has headache or not, or headache of the subject is relieved or not.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: April 19, 2022
    Assignee: National University Corporation Kochi University
    Inventors: Eiichi Nakai, Tetsuya Ueba
  • Patent number: 11298253
    Abstract: An apparatus for treating obesity of a patient having a stomach with a food cavity. The apparatus comprising a volume filling device adapted to be at least substantially invaginated by a stomach wall portion of the patient with the outer surface of the volume filling device resting against the stomach wall, such that the volume of the food cavity is reduced in size by a volume substantially exceeding the volume of the volume filling device. The apparatus further comprises at least one adjustable stretching device adapted to be at least substantially invaginated by a stomach wall portion of the patient with the outer surface of the stretching device resting against the stomach wall and adapted to stretch a portion of stomach wall, and a fluid connection device interconnecting the volume filling device and the stretching device.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: April 12, 2022
    Inventor: Peter Forsell
  • Patent number: 11291566
    Abstract: In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: April 5, 2022
    Assignee: Terumo Corporation
    Inventors: Tai D. Tieu, Gregory M. Cruise, Heather Griffith, Helen Nguyen, Minh Nguyen, Ponaka Pung, Shirley Vong
  • Patent number: 11284932
    Abstract: An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: March 29, 2022
    Assignee: Tsunami MedTech, LLC
    Inventors: John H. Shadduck, Michael Hoey
  • Patent number: 11285049
    Abstract: Wound dressings including a skin contact layer and a cover layer removably adhered to the top surface of the skin contact layer are described. The skin contact layer includes a lower substrate extending around a central aperture and a lower adhesive. The lower substrate includes a top surface and a bottom surface opposite the top surface. The lower adhesive is disposed on the bottom surface of the lower substrate. The cover layer substantially covers the central aperture of the lower substrate, and includes an upper substrate and a backing layer. An upper adhesive is positioned between the top surface of the lower substrate and a bottom surface of the backing layer. In embodiments, the cover layer can be removed and changed while the skin contact layer remains adhered to the skin around a wound.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: March 29, 2022
    Assignee: Hill-Rom Services, Inc.
    Inventors: David Lance Ribble, Kirsten Emmons
  • Patent number: 11278337
    Abstract: A technique for correcting a bone deformity, such as a bunion, may be performed using a fulcrum. In some examples, the technique involves inserting a fulcrum between a first metatarsal that is anatomically misaligned with respect to a second metatarsal. The technique further includes preparing an end of the first metatarsal and preparing an end of a medial cuneiform opposing the end of the first metatarsal. In addition, a distal portion of the first metatarsal is moved toward the second metatarsal in a transverse plane, thereby pivoting a proximal portion of the first metatarsal about the fulcrum and reducing an intermetatarsal angle between the first metatarsal and the second metatarsal.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: March 22, 2022
    Assignee: Treace Medical Concepts, Inc.
    Inventors: F. Barry Bays, Robert D. Santrock, Paul Dayton, Daniel J. Hatch, W. Bret Smith, Carlos Eduardo Gil, Sean F. Scanlan, Joe William Ferguson, John T. Treace
  • Patent number: 11278318
    Abstract: A pad is provided having a body for providing a gas seal over a surgical site, a port extending between a first surface of the body and a second surface of the body and sized accept a surgical instrument, and a lumen situated along the body and having a first opening and a second opening, the second opening aligned with the surgical site for communicating a fluid flow to the surgical site.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: March 22, 2022
    Assignee: Saphena Medical, Inc.
    Inventors: Mark J. Orphanos, Michael Glennon, Michael Barenboym
  • Patent number: 11272922
    Abstract: A locking member of a suture locking device includes a loop portion formed in an ?-shape when viewed from a width direction, and a pair of extensions extending from the loop portion towards a distal side, and an intersection portion in which the pair of extensions intersect is formed at a distal end of the loop portion. The loop portion is inserted into the hollow portion from the distal side with the thread being inserted through an inner space of loop portion, and the thread is pulled from a proximal side towards the intersection portion in the inner space of the loop portion so that the thread is locked to the loop portion.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: March 15, 2022
    Inventors: Osamu Goto, Takayuki Hatanaka
  • Patent number: 11272973
    Abstract: Electrosurgical apparatuses having bent tip applicators are provided. In one implementation, an electrosurgical apparatus includes an insulating outer tube having a longitudinal axis, a proximal end, and a distal end. An outer tube distal housing has its proximal end coupled to the distal end of the insulating outer tube. A distal end of the outer tube distal housing extends from the insulating outer tube at an acute angle relative to the longitudinal axis. The exemplary electrosurgical apparatus further includes an electrically conducting tube disposed within the insulating outer tube and moveable along the longitudinal axis of the insulating outer tube. An electrode is coupled to a distal end of the electrically conducting tube. The exemplary electrosurgical apparatus may include a knob coupled to the insulating outer tube to effect rotation of the outer tube distal housing in 360 degrees of rotation.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: March 15, 2022
    Assignee: Apyx Medical Corporation
    Inventor: Gary G. Gogolin
  • Patent number: 11275853
    Abstract: Conversation Print: A method, computer program product, and computing system for receiving voice-based content from a third-party. The voice-based content is processed to define a text-based transcript for the voice-based content. The voice-based content is processed to define speech-pattern indicia for the voice-based content. A conversation print for the voice-based content is generated based, at least in part, upon the text-based transcript and the speech-pattern indicia.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: March 15, 2022
    Inventors: Haydar Talib, Peter Stubley
  • Patent number: 11273040
    Abstract: A method for reducing left ventricular volume, which comprises identifying infarcted tissue during open chest surgery; reducing left ventricle volume while preserving the ventricular apex; and realigning the ventricular apex, such that the realigning step comprises closing the lower or apical portion of said ventricle to achieve appropriate functional contractile geometry of said ventricle in a dyskinetic ventricle of a heart.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: March 15, 2022
    Assignee: BIOVENTRIX, INC.
    Inventors: Sing-Fatt Chin, Arthur Bertolero, Lon S. Annest
  • Patent number: 11273029
    Abstract: An intraocular lens (IOL) includes one or more haptic structures coupled to hold the IOL (100A) system in an eye. The IOL also includes one or more mechanical-to-electrical transducers (107) that detect mechanical changes in the eye and, in response to the mechanical changes, output an electrical signal. An accommodation actuator (101) is electrically coupled to the one or more mechanical-to-electrical transducers, and in response to the electrical signal the optical power of the accommodation actuator changes.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: March 15, 2022
    Assignee: Verily Life Sciences LLC
    Inventors: Jeremy L. Emken, Shungneng Lee
  • Patent number: 11273236
    Abstract: A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: March 15, 2022
    Inventors: Eben Alsberg, Anna D. Dikina, Marsha W. Rolle, Hannah A. Strobel
  • Patent number: 11275854
    Abstract: A method, computer program product, and computing system for defining a conversation print for each of a plurality of known entities, thus defining a plurality of conversation prints. Voice-based content is received from a third-party. The voice-based content is compared to at least one of the plurality of conversation prints to identify the third party.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: March 15, 2022
    Inventor: Haydar Talib
  • Patent number: 11272927
    Abstract: A piece of buttress material and an end-effector of a surgical instrument including features which can aid a surgeon in properly and quickly attaching the piece of buttress material to the end-effector. In various embodiments, a piece of buttress material can include retention features which can be engaged with portions of an end-effector to releasably retain the piece of buttress material to at least a portion of the end-effector. Similarly, an end-effector can include features configured to engage portions of a piece of buttress material to releasably retain the piece of buttress material to the end-effector. In at least one embodiment, more than one piece of buttress material can be releasably retained to an end-effector.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: March 15, 2022
    Assignee: Cilag GmbH International
    Inventors: Jeffrey S. Swayze, Jerome R. Morgan, Frederick E. Shelton, IV, Thomas W. Huitema
  • Patent number: 11275855
    Abstract: A method, computer program product, and computing system for defining a conversation print for each of a plurality of known fraudsters, thus defining a plurality of fraudster conversation prints. The plurality of fraudster conversation prints is processed to identify one or more fraudster commonalities. A fraudster conversation template is generated based, at least in part, upon the one or more fraudster commonalities.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: March 15, 2022
    Inventor: Haydar Talib
  • Patent number: 11273032
    Abstract: A side-deliverable prosthetic heart valve includes an outer frame and a flow control component. The outer frame defines a central channel that extends along a central axis. The flow control component is disposed within the central channel and coupled to the outer frame. The flow control component has a set of leaflets mounted within an inner frame. The prosthetic valve is configured to be folded along a longitudinal axis and compressed along the central axis to place the prosthetic valve in a compressed configuration for delivery via a delivery catheter. The longitudinal axis is substantially parallel to a lengthwise axis of the delivery catheter when disposed therein. The prosthetic valve transitions to an expanded configuration when released from the delivery catheter. The flow control component elastically deforms from a substantially cylindrical configuration to a substantially flattened configuration when the prosthetic valve is placed in the compressed configuration.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: March 15, 2022
    Assignee: VDyne, Inc.
    Inventors: Mark Christianson, Robert Vidlund, Neelakantan Saikrishnan, Chad Perrin
  • Patent number: 11272904
    Abstract: A system for delivering ultrasound energy to an internal anatomical target includes an ultrasound transducer having multiple transducer elements collectively operable as a phased array; multiple driver circuits, each being connected to at least one of the transducer elements; multiple phase circuits; a switch matrix selectably coupling the driver circuits to the phase circuits; and a controller configured for (i) receiving as input a target average intensity level and/or an energy level energy to be applied to the target and/or a temperature level in target, (ii) identifying multiple sets of the transducer elements, each of the sets corresponding to multiple transducer elements for shaping and/or focusing, as a phased array, ultrasound energy at the target across tissue intervening between the target and the ultrasound transducer, and (iii) sequentially operating the transducer-element sets to apply and maintain the target average energy level at the target.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: March 15, 2022
    Assignee: INSIGHTEC, LTD.
    Inventors: Kobi Vortman, Shuki Vitek, Yoav Levy
  • Patent number: 11266331
    Abstract: The present technology relates to an optical apparatus and an information processing method capable of more easily obtaining an indicator value. In the optical apparatus according to the present technology, irradiation light including a predetermined irradiation wavelength band is emitted, first reflected light being a reflected light in a first wavelength band obtained by reflection of the emitted irradiation light on a predetermined object and second reflected light being reflected light in a second wavelength band obtained by reflection of the irradiation light on the object are received at a plurality of pixels; and a value of a predetermined indicator relating to a region in a predetermined range of the object is obtained on the basis of a received light amount of each of the received first reflected light and the received second reflected light. For example, the present technology can be applied to optical apparatuses, electronic apparatuses, imaging apparatuses, and information processing apparatuses.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: March 8, 2022
    Inventors: Shinichiro Gomi, Kenichiro Nakamura, Yoichi Toriumi, Morio Ogura
  • Patent number: 11266389
    Abstract: A device for manipulating the left atrial appendage (LAA) of a heart, including: an elongated and hollow guide instrument which is shaped and sized to be transvascularly and transseptally introducible into the left atrium (LA); a suction channel passing through the guide instrument, the suction channel terminating with a concave holder, wherein the suction channel and the concave holder are shaped and sized to be enclosed within a lumen of the guide instrument during the transvascular and transseptal introduction into the LA and to forwardly extend from the lumen of the guide instrument after reaching the LA, and wherein the concave holder is configured to radially expand; a loop fastener shaped and sized to be enclosed within the lumen of the guide instrument during the transvascular and transseptal introduction into the LA and to forwardly extend from the lumen of said guide instrument.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: March 8, 2022
    Assignee: Tel HaShomer Medical Research infrastructure and Services Ltd.
    Inventor: Leonid Sternik
  • Patent number: 11266500
    Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: March 8, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark M. Dehdashtian, Jane M. Olin
  • Patent number: 11266493
    Abstract: An assembly for lifting a lower eyelid can be surgically implanted into a patient. The assembly can include a mounting plate, an eyelid support member, and an elongate shaft that extends between and couples the mounting plate to the eyelid support member. The mounting plate can be coupled to facial bone, such as the zygomatic bone, while the eyelid support member contacts and lifts up an inferior tarsus and the lower eyelid of the patient.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: March 8, 2022
    Inventor: Nicholas Testa
  • Patent number: 11266183
    Abstract: An active compression device includes a textile wrap configured to be secured around a waist of a user. Additionally, the active compression device includes a controller assembly disposed within the textile wrap, wherein the controller assembly includes one or more shape memory wires configured to apply compression to the user's back in response to actuation of the one or more shape memory wires. The controller assembly also includes processing circuitry configured to receive a selection of a predetermined compression profile, and in response to receiving the selection of the predetermined compression profile, activate a predetermined pattern of compressions corresponding to the selected predetermined compression profile.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: March 8, 2022
    Inventors: Vince Rizzo, Jeffrey Schwegman
  • Patent number: 11259825
    Abstract: Delivery systems, and methods using the same, having an ultrasound viewing window for improved imaging and a needle for ablation treatment of target tissues. In an embodiment, the target tissue is a fibroid within a female's uterus. In an embodiment, the delivery system includes a rigid shaft having a proximal end, a distal end, and an axial passage extending through the rigid shaft. In an embodiment, the axial passage is configured for removably receiving the ultrasound imaging insert having an ultrasound array disposed a distal portion.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: March 1, 2022
    Assignee: Gynesonics, Inc.
    Inventors: Robert K. Deckman, Craig Gerbi, Michael Munrow, Jessica Grossman
  • Patent number: 11260135
    Abstract: The invention relates generally to the use of dyes to enhance visualization of tissues and boundaries of openings in tissues during cataract surgery.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: March 1, 2022
    Assignee: Excel-Lens, Inc.
    Inventor: David Mordaunt
  • Patent number: 11259837
    Abstract: A device for dividing a fibrous structure comprising a catheter; an expandable member positioned near a distal end of the catheter and in fluid communication with a lumen of the catheter; and a cutting element situated on an outer surface of the expandable member. A method for dividing a fibrous structure comprising positioning, proximate the fibrous structure, an expandable member having a cutting element situated thereon; expanding the expandable member outwards to tension the fibrous structure across the cutting element; and activating the cutting element to weaken or cut the fibrous structure. A method for treating carpal tunnel syndrome comprising inserting a needle into the carpal tunnel; directing a guidewire to a position proximate the transverse carpal ligament; advancing, along the guidewire, a device having an expandable member and a cutting element; positioning the cutting element; tensioning the ligament across the cutting element; and weakening or cutting the ligament.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: March 1, 2022
    Assignee: PAVmed Inc.
    Inventors: Lishan Aklog, Brian J. deGuzman
  • Patent number: 11253355
    Abstract: A prosthetic heart valve for functionally replacing a previously implanted prosthetic heart valve is disclosed. The prosthetic heart valve includes a collapsible support structure with leaflets and anchors mounted to the support structure. The support structure also includes an inflow end and an outflow end. The anchors include a radially outwardly extending first anchor proximate to the inflow end and a radially outwardly extending second anchor proximate to the outflow end. The first anchor includes a first configuration and the second anchor includes a second configuration where the first configuration is different than the second configuration. The previously implanted prosthetic heart valve serves as a platform for securement of the prosthetic heart valve to the patient's native tissue.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: February 22, 2022
    Assignee: Medtronic, Inc.
    Inventors: Jose M. Revuelta, Jack D. Lemmon, Timothy R. Ryan
  • Patent number: 11253717
    Abstract: In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: February 22, 2022
    Assignee: BTL Healthcare Technologies A.S.
    Inventors: Tomás Schwarz, Ondra Prouza
  • Patent number: 11253302
    Abstract: Embodiments are directed to fusion implants, insertion instruments, and methods of using the same for implanting one or more fusion implants across a sacroiliac joint and into an ilium and sacrum for fusing the sacroiliac joint. In some cases, fusion-promoting material may be inserted in the fusion implant for further promoting fusion across the sacroiliac joint. In some cases, neurophysiologic monitoring may be performed as the fusion implants are placed across the sacroiliac joint.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: February 22, 2022
    Assignee: NuVasive, Inc.
    Inventors: Brett Menmuir, Morton Albert, Dan Zatta
  • Patent number: 11254838
    Abstract: A coating composition includes a polymer prepared from a mixture of reactants including (a) a fluorinated polysiloxane and (b) an alkoxy silane functional resin. The alkoxy silane functional resin includes a polyurethane resin or an acrylic resin. A substrate at least partially coated with the coating composition is also disclosed. A method of condensing a polar fluid by contacting a substrate at least partially coated with the coating composition with a polar fluid, such that the polar fluid condenses on at least a portion of the coated substrate is also disclosed.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: February 22, 2022
    Assignee: PPG Industries Ohio, Inc.
    Inventors: David N. Walters, Emily S. Reinhardt, Cynthia Kutchko
  • Patent number: 11253170
    Abstract: Implementations described herein include surgical distraction devices having a distal movement assembly having a pusher plate comprising a first slot extending along a first axis disposed in a first side and a second slot extending along a second axis disposed in a second side thereof. The first axis is oriented at an angle of from about 60 to about 160 degrees from the second axis. The device further includes a first and second paddles, each paddle having a corresponding engagement mechanism for movably coupling the respective first or second paddle to the pusher plate when engaged in the respective slot. Rotational actuation of the proximal drive assembly causes proximal or distal movement of the pusher plate, causing the first and second engagement members to move relative to their respective slots, thereby moving the first paddle and the second paddle in opposing directions. Methods of using such surgical distraction devices to determine size of an intervertebral space are also described.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: February 22, 2022
    Assignee: Zimmer Biomet Spine, Inc.
    Inventors: Terry Ziemek, Susanne Duman, William Sandul, Samuel Jebsen
  • Patent number: 11250952
    Abstract: The method of event-driven health and wellness decision support considers an individual's medical records and lifestyle; applies healthcare best practices; and recommends next steps. Medical and lifestyle records are input, converted to events and inserted in timestamp order in an event queue. Events are processed in queued order by handlers, and results recorded in a data structure called a “person state”. Some handlers create additional events and insert them in the event queue in timestamp order. Those events are in turn processed in timestamp order. Other handlers create no events, allowing processing of all queued events to eventually complete. After events representing actual occurrences are processed, events representing postulated activities are created, queued, and processed until a specific patient state representing a health and wellness goal obtains. This allows several activity paths to be compared to determine the best path to an optimal health goal. Next steps are recommended as output.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: February 15, 2022
    Assignee: Software Partners LLC
    Inventor: Alean Kirnak
  • Patent number: 11241255
    Abstract: A novel posterolateral inter-muscular approach has been developed to access the cervical spine. The approach includes elevating the splenius capitis and trapezios muscles dorsally to create a window for deep spine access, wherein the window comprises: i) an anterior superior border of the trapezius muscle; ii) an anterior inferior border of the splenius capitis muscle, and iii) a posterior superior border of the levator scapulae muscle. Preferably, a device such as an implant or an instrument is then passed through the window to manipulate the spine.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: February 8, 2022
    Assignee: DePuy Synthes Products, Inc.
    Inventors: William C. Horton, John Riley Hawkins, Christopher L. Ramsay, Edward B. Zalenski, Alexander Grinberg, Hassan Serhan, Ernest Quintanilha
  • Patent number: 11235089
    Abstract: The present invention is directed to injectable acid soluble collagen compositions comprising a neutralized solution of an acid soluble collagen, EDTA and preferably a polyol, wherein the composition is injectable at physiological pH and the acid soluble collagen polymerizes upon exposure to tissue. The invention is suitable for use in soft tissue augmentation, promoting soft tissue regeneration and coating medical implants and devices.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: February 1, 2022
    Assignees: Shanghai Haohai Biological Technology Co., Ltd., Shanghai Qisheng Biological Preparation Co., Ltd.
    Inventors: Dale P. Devore, Robert J. Brooks, Todd Byrne