Abstract: A microfluidic valve assembly includes a structure defining a microfluidic fluid path and an actuator that can be moved between different positions controlling flow through the channel. In one embodiment, the actuator can be threaded into at least a portion of the structure, and can be moved rotationally between a first position, causing relatively greater constriction of a microfluidic fluid path, and a second position causing relatively lesser constriction of the fluid path. Actuating the actuator, e.g., by rotation, can deform material between the valve and the fluid path, thereby constricting at least a portion of the underlying fluid path and regulating the flow of a fluid in the fluid path. In another aspect, the invention provides a reservoir into which fluid can be placed and from which fluid can be introduced into a microfluidic system. In one embodiment, the reservoir is expandable and thereby able to store fluid under pressure for delivery to a microfluidic system.
January 31, 2006
May 13, 2010
President and Fellows of Harvard college
Douglas B. Weibel, Andrew Lee, Scott Potenta, Adam Siegel, Maarten Kruithof, George M. Whitesides
Abstract: A throttling choke valve having a wear sleeve lining the interior surface of the cylindrical passage downstream of the valve sealing mechanism. A preferred embodiment of the wear sleeve has a removable retainer ring that fits between the wear sleeve and the fluid outlet. The retainer ring has a distal end that opens into the pipeline. At the distal end of the retainer ring the thickness of the wall of the retainer is decreased such that the interior surface is curved outward toward the interior surface of the pipeline.
Abstract: A stuffing box for use in a control for an emergency valve for controlling discharge from a liquid storage tank, such as a gasoline storage tank, with the tank having an outlet port with a conduit member coacting with the port in depending relation therefrom. The stuffing box is adapted to be mounted on the conduit member and to extend from the interior to the exterior thereof. The stuffing box comprises a barrel member defining a passageway open at opposite ends. A crank including a shaft rotatably disposed in the passageway of the barrel member is mounted on the barrel member. Sealing means coacts between the shaft and the barrel member for sealing the shaft against leakage of liquid from the conduit lengthwise of the barrel member, and a releasable non-threaded detent is disposed generally adjacent the exterior end of the barrel member for locating and maintaining the shaft relative to the barrel member lengthwise thereof.
Abstract: A no-drip valve apparatus for regulating a fluid flow from an inlet to an outlet. A pressure activated supply valve means controls the flow of fluid through the valve. A partition member cooperates with a vacuum chamber to retract and retain any remaining oil in the valve or the oulet nozzle when the pressure activated supply valve means cuts off the flow of oil through the valve. The partition member is resiliently displaced by pressure fluid from a supply chamber adjacent the inlet and is displaced in one direction prior to flow of fluid to the outlet and is displaced in the other direction upon termination of the flow of fluid through the outlet.
Abstract: A sliding gate valve has a sliding plate provided with an under-hung insulating member having a hollow nose, the hollow nose having a tapered bore in which a molten metal resistant liner is cemented, the liner being tapered to fit the bore and a frangible cement being used to detachably secure the liner in the nose so that the liner can be readily replaced when worn.
Abstract: A check valve comprising a sectional valve body adapted to be interposed in a flow line, a valve seat provided in one body portion, a pivotal clapper member movable toward and away from said valve seat to provide alternate open and closed positions for the valve and hanger means provided in the body including means for urging the clapper toward a normal closed position against the valve seat.