Three Or More Electrodes Patents (Class 204/411)
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Patent number: 12072328Abstract: Provided is a coreflood apparatus that comprises a housing, an inlet, an outlet, and two chambers positioned within the housing that are configured to retain porous media. The apparatus includes a partition coupled to an inner surface of the housing between the two chambers and a sensor mounting location. Provided is a method of introducing a fluid into the coreflood apparatus and allowing fluid to pass through chambers in the apparatus having a sensor mounting location there between. Further provided is a coreflood system comprising a coreflood apparatus, a calcium ion sensor, and a data processing device. Provided is a method of introducing fluid into the coreflood system and allowing fluid to pass through chambers in the system having a calcium ion sensor there between. The method further comprises detecting calcium ions in the fluid and determining calcium ion concentration data.Type: GrantFiled: December 8, 2021Date of Patent: August 27, 2024Assignee: SAUDI ARABIAN OIL COMPANYInventors: Mohammed Badri Al-Otaibi, Dong Kyu Cha
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Patent number: 11802848Abstract: A pH measuring device configured to measure a pH of a target liquid includes a main body block including a cavity, a supply line communicating with the cavity, a first drain line communicating with the cavity, and a target liquid supply valve configured to adjust a supply of the target liquid into the supply line. The main body block has an integral structure in which a pH sensor is supported such that the pH sensor is in contact with the target liquid within the cavity.Type: GrantFiled: November 11, 2019Date of Patent: October 31, 2023Assignee: TOKYO ELECTRON LIMITEDInventor: Toshiyuki Shiokawa
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Patent number: 11751805Abstract: A detection system (100) detects at least ethanol in human sweat. The detection system (100) includes at least one sensor (105) that is an electrochemical gas sensor. The at least one sensor (105) is configured at least for the detection of ethanol. The detection system (100) further includes a measuring chamber (107), in which substances excreted by the user via the user's skin can be fed via a waterproof, gas-permeable diffusion membrane to the at least one sensor (105). The detection system (100) further includes at least one seal (127), which is configured to be brought into direct contact with the skin of a user and to protect at least the measuring chamber (107) from environmental effects.Type: GrantFiled: June 19, 2020Date of Patent: September 12, 2023Assignee: Dräger Safety AG & Co. KGaAInventors: Rainer Polzius, Michael Sick, Jens Rekow, Marie-Isabell Mattern-Frühwald
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Patent number: 11707748Abstract: Devices, systems, and methods for applying a dielectrophoretic force on a particle include: a cell defining at least one channel for confining the particle; and a first electrode and a second electrode electrically isolated from the first electrode, at least one of the first and second electrodes being formed from a two-dimensional (2D) material providing an atomically sharp edge. The first and second electrodes are arranged sufficiently close to one another and sufficiently close to the channel such that application of a sufficient voltage across the first and second electrodes generates an electric field in at least part of the channel, the electric field having an electric field gradient sufficient to apply the dielectrophoretic force on the particle in the channel.Type: GrantFiled: December 14, 2020Date of Patent: July 25, 2023Inventors: Sang-Hyun Oh, Steven John Koester
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Patent number: 11483686Abstract: Example systems are described for remotely interacting with a portable field measurement device. Systems can include a controller that can: couple to a mobile device; receive user input from a user through the mobile device; cause the portable field measurement device to execute the operations directed by the user; electronically record data output from the portable field measurement device resulting from the directed operations; and report the data to the user via the mobile device, and/or to a remote electronic database. In some embodiments, a robotic arm can be used to actuate the portable field measurement device.Type: GrantFiled: November 11, 2019Date of Patent: October 25, 2022Assignee: ENGEO INCORPORATEDInventors: Gilead Wurman, Michael John Price, Joseph Gray
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Patent number: 11231390Abstract: An embodiment provides a probe, including: an ion selective shell that includes a pH electrode bathed in an electrolyte and/or buffer solution; a plurality of conductive electrodes coaxially arranged respective to the pH electrode; the plurality of conductive electrodes being electrically isolated on a substrate displaced between the pH electrode and a reference electrode, and including: at least a first conductive electrode that is exposed to sample fluid at a terminal end of the probe proximate to the ion selective shell and disposed on the surface of an electrode substrate proximate to a terminal end of the reference electrode; and at least a second conductive electrode that is exposed to the sample fluid at the terminal end of the probe proximate to the ion selective shell and disposed on the surface of an el electrode substrate proximate to the terminal end of the reference electrode; the probe further including the reference electrode arranged about and along a longitudinal axis of the probe and bathedType: GrantFiled: June 16, 2016Date of Patent: January 25, 2022Assignee: HACH COMPANYInventors: Michael Carrabba, Corey Salzer
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Patent number: 10989688Abstract: This disclosure provides techniques for extending useful life of a reference electrode, as well as a novel voltametric system and measurement cell design and related chemistries. An automated, repeatable-use system features a reference electrode that directly immerses a metallic conductor into an analyte, with electrolytes (e.g., chlorides) used for measurement being separately added and removed for each measurement cycles; the metallic conductor can optionally be left exposed to clean dry air in between measurements. In one implementation, the system can be restricted to application with specific analytes (e.g., ground water) that are known in advance to be free of substances that could degrade reference electrode use or lifetime. Cleaning solutions can optionally be used that would not be practical with conventional (insulated) reference electrode designs.Type: GrantFiled: February 15, 2019Date of Patent: April 27, 2021Assignee: AMS Trace Metals, Inc.Inventor: Vladimir Dozortsev
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Patent number: 10983083Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.Type: GrantFiled: June 15, 2017Date of Patent: April 20, 2021Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest
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Patent number: 10883182Abstract: A microfluidic electrolyzer includes a housing having a power source, a sea water reservoir, a downstream microfluidic reactor connected to the reservoir and a collector for storing the separated gases emanating from the microfluidic reactor. The downstream microfluidic reactor includes a substrate, a microchannel embedded with respect to the substrate and providing a water inlet end at one end and a product outlet at the other, and a pair of electrodes. The electrodes are electrically connected with the power source and each electrode has an operative end inserted within the microchannel constituting an anode and a cathode. The cathode and the anode are positioned one ahead of the other, from the water inlet end and maintained in direct contact with the water to generate the oxygen and hydrogen involving electrolysis of the water and in-situ separate pathways of the hydrogen and oxygen free of any mixing with each other.Type: GrantFiled: January 16, 2017Date of Patent: January 5, 2021Assignee: INDIAN INSTITUTE OF TECHNOLOGY, GUWAHATIInventors: Dipankar Bandyopadhyay, Tapas K Mandal, Saptak Rarotra
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Patent number: 10458975Abstract: An interlock data collection and calibration system has a device computer, and a gas sample delivery system for delivering a first gas sample and a second gas sample to the ignition interlock device, the first and second gas samples having different predetermined concentrations of alcohol. The device computer includes a calibration program for calibrating the ignition interlock device using the first gas sample, and then delivering the second gas sample to the ignition interlock device to verify that the ignition interlock device correctly determines the second alcohol concentration of the second sample gas.Type: GrantFiled: May 7, 2015Date of Patent: October 29, 2019Assignee: 1A Smart Start, LLCInventor: Michael Lyon
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Patent number: 10444183Abstract: A sensor arrangement for determining at least one measurand of a measuring medium includes at least one first sensor with a first sensing element used to record measured values of a first measurand of the measuring medium, a housing having a housing wall which surrounds a housing interior containing the first sensing element, wherein the housing interior contains a medium in particular, a liquid which has a predetermined value of the first measurand.Type: GrantFiled: September 28, 2016Date of Patent: October 15, 2019Assignee: Endress+Hauser Conducta GmbH+Co. KGInventors: Michael Weiss, Angela Eubisch, Michael Hanko
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Patent number: 10362981Abstract: A method for diagnosing a body malfunction is provided. At least one change in urinary parameter values, being indicative of the body malfunction, is monitored and detected. A volumetric urinary output of kidneys is monitored using a urine flow monitoring apparatus having a low flow metering device. It is determined whether a change exists in at least one of a volume value of the volumetric urinary output, and a trend of the corresponding urinary parameter value during a predetermined period. Signals are received from a plurality of electrodes, representing the urinary parameter values. The body malfunction is detected based on the determination of the change in at least one of the volume value and the trend.Type: GrantFiled: June 30, 2014Date of Patent: July 30, 2019Assignee: FLOWSENSE LTD.Inventors: Ilan Paz, Martin Clive Henry Jackson, Stanley Chimes
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Patent number: 9970899Abstract: A fluid testing system can be used to measure the levels of contaminants in a fluid system. The system can utilize anodic stripping voltammetry or some other chemical, electrical, or electrochemical process to measure the contaminant levels. Wire electrodes may be used to facilitate the tests. Unused portions of the electrode wires can be fed into the test chambers between tests to ensure clean and reliable electrodes for subsequent testing.Type: GrantFiled: July 13, 2017Date of Patent: May 15, 2018Assignee: KETOS, INC.Inventors: Meena Sankaran, Mazhar N. Ali, Harish Mehta
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Patent number: 9874540Abstract: A sensor with a sensor housing or body, a plastic molded table positioned in the sensor housing; and a counter electrode carried on a first end of the table.Type: GrantFiled: October 3, 2014Date of Patent: January 23, 2018Assignee: Life Safety Distribution AGInventors: Paul Christopher Westmarland, Martin Jonathan Kelly, John Chapples, Neils Richard Stewart Hansen, Arkadiusz Edward Majczak, Stuart Alistair Harris
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Patent number: 9766218Abstract: The present disclosure is directed to methods and systems for creating a gas curtain inlet for a detector of a substance of interest. The methods and systems include introducing a carrier gas into an inlet to block out atmospheric air without having to make the inlet a sealed system.Type: GrantFiled: October 31, 2014Date of Patent: September 19, 2017Assignee: Morpho Detection, LLCInventors: Hanh Lai, Bradley Douglas Shaw, Hartwig Schmidt, Stephen Davila, Robert Michalczyk
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Patent number: 9541436Abstract: A fluid measurement system and method for determining distributed measurement of a fluid type and a fluid velocity in a wellbore, pipeline or other conduit in which fluid is moving. Measurement is made by immersing one or more cables having sequential sampling sections in the fluid and monitoring a cooling effect across a cable on the sampling sections and the response to injection of a high frequency pulse each sampling section. A probabilistic model is then used to determine the distributed velocity and fluid types along the conduit.Type: GrantFiled: November 21, 2012Date of Patent: January 10, 2017Assignee: Lufkin Industries, LLCInventor: David Sirda Shanks
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Patent number: 9011697Abstract: A method for the treatment of fluid including the step of exposing the fluid to a pulsed plasma discharge. The pulsed plasma discharge will be generated using a suitable electrode configuration to generate the plasma discharge in the fluid. Apparatus useful in the method may include a vessel, at least two electrodes for generating a plasma discharge in water, and a flow inlet and a flow outlet to allow water to be passed through the vessel. Also described is an in-line water treatment, where a pulsed plasma discharge is used in a pipe carrying moving water. Plasma based fluid treatment system may have many advantages in comparison to other treatment methods, such as very minimal maintenance, low operating power, and minimal pressure loss through the device.Type: GrantFiled: June 15, 2007Date of Patent: April 21, 2015Assignee: Drexel UniversityInventors: Christopher A. Campbell, Young I. Cho, Alexander F. Gutsol, Alexander Fridman, Frank T. Snyder, Vincent Szarko, Erik Yelk, Jesse Zanolini, Victor Vasilets
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Patent number: 8986527Abstract: The present disclosure relates to a removable assay cartridge containing a polymer body with channels for fluid movement for an in vitro medical diagnostic device. The device also includes a removable calibration fluid cartridge.Type: GrantFiled: December 6, 2012Date of Patent: March 24, 2015Assignee: Edan DiagnosticsInventors: Chao Lin, Paul Swanson, Zhixiang Jason Zhao
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Patent number: 8951395Abstract: A biosensor for electrochemically measuring a sample may include a first member made of an insulating material, an electrode system including a working electrode and a counter electrode formed on the first member, a second member fixed over the first member, a sample flow channel provided between the first member and the second member, a hydrophilic section provided on at least a part of the internal surface of the sample flow channel and extending from a first end near the electrode system to a second end on the opposite side, and a flow stop area provided on a section adjacent to the second end on the first member or on the internal surface of the sample flow channel.Type: GrantFiled: November 5, 2008Date of Patent: February 10, 2015Assignee: Nippon Kayaku Kabushiki KaishaInventors: Reiko Machida, Takao Yokoyama, Yayoi Irie, Hisako Takagi, Yoshihiko Umegae, Toshio Tanabe
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Patent number: 8926811Abstract: The present invention provides an apparatus and method for performing heat-exchanging reactions on an electro wetting-based micro fluidic device. The apparatus provides one or multiple thermal contacts to an electro wetting-based device, where each thermal contact controls the part of the electro wetting-based device it communicates with to a designed temperature. The electrowetting-based device can be used to create, merge and mix liquids in the format of droplets and transport them to different temperature zones on the micro fluidic device. The apparatus and methods of the invention can be used for heat-exchanging chemical processes such as polymerase chain reaction (PCR) and other DNA reactions, such as ligase chain reactions, for DNA amplification and synthesis, and for real-time PCR.Type: GrantFiled: June 27, 2008Date of Patent: January 6, 2015Assignee: Digital BiosystemsInventor: Chuanyong Wu
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Patent number: 8801918Abstract: Methods and devices for point of care determination of heparin concentration in blood are described. Cartridges including protamine ion sensitive electrodes (ISEs) and reference electrodes and systems for automatically determining heparin concentration in the cartridges are provided. Some systems add blood to a protamine bolus sufficient to bind all heparin, leaving excess protamine. The excess protamine concentration can be determined by measuring the initial slope of the electrode potential rate of change, and comparing the slope to known protamine concentration slope values In some cartridges, an oscillating pressure source moves the blood-protamine mixture back and forth across the protamine ISE. Some systems also use a second blood sample having the heparin removed or degraded to create a blank reference sample. Protamine ISEs can include polyurethane polymer, DNNS ionophore, and NPOE plasticizer.Type: GrantFiled: March 29, 2010Date of Patent: August 12, 2014Assignee: Medtronic, Inc.Inventors: Wei Qin, Daniel S. Cheek, Christopher Hobot, Kelvin Bonnema, Randy Meyer, Douglas Dean Nippoldt, Vitally G. Sitko, Qingshan (Sam) Ye, Narayanan Ramamurthy
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Patent number: 8771493Abstract: A liquid dielectrophoretic device comprises: a first container unit defining a first micro containing space including an electrode pair for generating a dielectrophoretic force; a second container unit defining a second micro containing space and including an electrode pair for generating a dielectrophoretic force; and a fluid channel unit defining a micro-channel between the first and second micro containing spaces and including an electrode pair having a middle region layer that has first and second enlarged sections and a middle section disposed between the first and second enlarged sections. The first and second enlarged sections are enlarged gradually from the middle section to the first and second micro containing spaces. A method for controllably transporting a liquid using the liquid dielectrophoretic device is also disclosed.Type: GrantFiled: July 8, 2011Date of Patent: July 8, 2014Assignee: National Chiao Tung UniversityInventors: Shih-Kang Fan, I-Pei Lu
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Publication number: 20140183059Abstract: The multiplexed electrochemical microfluidic paper-based analytical device comprises multiple detection zones for the detection of multiple biochemical analytes from one single sample. Cavity valves integrated on the device will deliver the sample to different detection zones. These analytes include, but are not limited to, urea, creatinine, creatine, glucose, lactate, ethanol, uric acid, cholesterol, pyruvate, creatinine, ?-hydroxybutyrate, alanine aminotrasferase, aspartate aminotransferase, alkaline phosphatase, and acetylcholinesterase (or its inhibitors). This system will provide a simple and low-cost POC approach to obtain quantitative and multiple biological information from one sample (e.g. one drop of blood).Type: ApplicationFiled: March 6, 2014Publication date: July 3, 2014Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: George M. WHITESIDES, Xiujun LI, Frederique DEISS, Zhihong NIE, Xinyu LIU
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Patent number: 8741118Abstract: A sensor control apparatus includes: a gas sensor including an oxygen concentration detection cell having a first solid electrolyte body, a reference electrode and a detection electrode, and a heater; an electric current supply unit that supplies electric current to the oxygen concentration detecting cell; an activation determination unit; a heater control unit that sets a first target temperature equal to or higher than an activation determination temperature when the activation determination unit determines that the temperature of the gas sensor is equal to or higher than the activation determination temperature; an automatic stop detection unit; and a first temperature switching unit that controls electric current supplied to the heater such that the target temperature of the heater is switched to a second target temperature different from a temperature at which blackening is generated in the first solid electrolyte body when an automatic stop is detected.Type: GrantFiled: December 21, 2010Date of Patent: June 3, 2014Assignee: NGK Spark Plug Co., Ltd.Inventor: Hiroshi Inagaki
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Publication number: 20140138260Abstract: The present invention relates to a cartridge for conducting diagnostic assays. The cartridge consists of an assembly of components that are easily assembled. The cartridge provides means for receiving a patient sample, precisely controlling fluid introduction, onboard storage of assay fluid and conducting different assay protocols and detection of a plurality of analytes. Methods of use for the cartridge are described. The disclosed invention is suitable for point of care environments or any place where rapid, ultrasensitive testing is required.Type: ApplicationFiled: September 27, 2011Publication date: May 22, 2014Applicant: Proxim DiagnosticsInventor: Mikhail Briman
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Patent number: 8728288Abstract: The invention relates to a sensor assembly comprising a first electronic wiring substrate having a first and a second surface and at least one analyte sensor formed on the first surface thereof, the at least one analyte sensor being connected with one or more electrical contact points, a second electronic wiring substrate having a first and a second surface and at least one analyte sensor formed on the first surface part thereof, the at least one analyte sensor being connected with one or more electrical contact points, and a spacer having a through-going recess with a first and a second opening, wherein the first substrate, the second substrate and the spacer are arranged in a layered structure, where the first surface of the first substrate closes the first opening of the spacer and the first surface of the second substrate closes the second opening of the spacer, thereby forming a measuring cell which is faced by at least one sensor from each of the substrates.Type: GrantFiled: April 24, 2008Date of Patent: May 20, 2014Assignee: Radiometer Medical ApsInventors: Flemming Aas, Erik Helleso Nicolajsen
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Publication number: 20140131223Abstract: A gas-phase detection system based on detecting optochemical and optoelectrochemical signals. The sensing platform is particularly powerful for detection of nitrogen oxides at low ppbV concentrations. The optochemical analysis is based on the color development due to a chemical reaction taking place in an optimized material. The electrochemical analysis can be based on the doping level or redox potential changes of an electrochemical sensor; and optoelectrochemical detection can be based on a combination of the electrochemical and optoelectrochemical methodologies. Each independent signal can be simultaneously detected, increasing the reliability of detection.Type: ApplicationFiled: January 21, 2014Publication date: May 15, 2014Applicant: ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Nongjian Tao, Erica Forzani, Rodrigo A. Iglesias
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Patent number: 8702934Abstract: A gas sensor including a gas sensor element that extends in an axial direction and has a detection section at a front-end side thereof, and an electrode pad at a rear-end side thereof; a connection terminal that is electrically connected to the electrode pad; and an insulated separator that extends along the axial direction and has an inserting hole into which the connection terminal is inserted. An element side section is arranged within the inserting hole and is connected the electrode pad, and an external circuit side section extends further to the outside in a diametrical direction than an outer surface of the separator through one or more first bending sections from the element side section.Type: GrantFiled: January 18, 2011Date of Patent: April 22, 2014Assignee: NGK Spark Plug Co., Ltd.Inventors: Masao Tsuzuki, Tomohiro Tajima, Tomoki Fujii, Hisaharu Nishio, Takaya Yoshikawa, Kunihiko Yonezu
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Patent number: 8652313Abstract: A wet flow-type ion selective electrode device requires not only a large amount of test solution but also cumbersome management works such as flow path cleaning and device conditioning. Provided is an ion selective electrode cartridge which includes at least one ion selective electrode forming an electrical path with a reference electrode when a test solution is infused, and in which the ion selective electrode and the reference electrode is arranged to surround a container.Type: GrantFiled: September 17, 2010Date of Patent: February 18, 2014Assignee: Hitachi Chemical Company, Ltd.Inventors: Teruyuki Kobayashi, Tsuyoshi Uchida
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Publication number: 20140027313Abstract: The cartridge includes a sensor structure that has multiple sensors positioned on a substrate. The cartridge also includes a common channel defined in the substrate such that a fluid flowing in the common channel contacts each of the sensors as a result of the fluid flowing from an inlet of the common channel to an outlet of the common channel.Type: ApplicationFiled: June 7, 2013Publication date: January 30, 2014Inventor: Jen-Jr Gau
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Patent number: 8617371Abstract: A wet flow-type ion selective electrode device requires not only a large amount of test solution but also cumbersome management works such as flow path cleaning and device conditioning. Provided is an ion selective electrode cartridge which includes at least one ion selective electrode forming an electrical path with a reference electrode when a test solution is infused, and in which the ion selective electrode and the reference electrode is arranged to surround a container.Type: GrantFiled: September 17, 2010Date of Patent: December 31, 2013Assignee: Hitachi Chemical Company, Ltd.Inventors: Teruyuki Kobayashi, Tsuyoshi Uchida
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Patent number: 8603310Abstract: A sensor control apparatus (3) includes a full-range gas sensor composed of an oxygen concentration detection cell having a pair of electrodes (21, 22) and an oxygen pump cell having a pair of electrodes (19, 20). In an electric circuit section (30), an Ip current flowing between the electrodes (19, 20) is controlled such that an electromotive force Vs produced between the electrodes (21, 22) becomes equal to a reference voltage. The reference voltage is usually set to a first reference voltage. However, when the subject gas is air, the reference voltage is set to a second reference voltage. Humidity of the subject gas is detected on the basis of an error ?Ip between an Ip current detected when the reference voltage is set to the first reference voltage, and an Ip current detected when the reference voltage is set to the second reference voltage.Type: GrantFiled: April 19, 2010Date of Patent: December 10, 2013Assignee: NGK Spark Plug Co., Ltd.Inventors: Noboru Ishida, Kentaro Mori, Tomohiro Tajima
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Patent number: 8444835Abstract: An electronic fluidic interface for use with an electronic sensing chip is provided. The electronic fluidic interface provides fluidic reagents to the surface of a sensor chip. The electronic sensing chip typically houses an array of electronic sensors capable of collecting data in a parallel manner. The electronic fluidic interface is used, for example, as part of a system that drives the chip and collects, stores, analyzes, and displays data from the chip and as part of a system for testing chips after manufacture. The electronic fluidic interface is useful, for example, nucleic sequencing applications.Type: GrantFiled: September 9, 2010Date of Patent: May 21, 2013Assignee: Intel CorporationInventors: Oguz H. Elibol, Jonathan S. Daniels, Stephane L. Smith
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Patent number: 8419927Abstract: In vitro analyte sensors and methods of analyte determination are provided. Embodiments include sensors that include a pair of electrodes to monitor filling of the sample chamber with sample.Type: GrantFiled: December 6, 2011Date of Patent: April 16, 2013Assignee: Abbott Diabetes Care Inc.Inventors: Yi Wang, Benjamin J. Feldman, Jared L. Watkin
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Patent number: 8398844Abstract: Method for diagnosing a NOx readings recorder which acquires a NOx concentration in an exhaust gas tract of an internal combustion engine and comprises two measuring chambers (110, 120), wherein the exhaust gas to be measured is supplied to the first measuring chamber (110) and an oxygen concentration is set by means of a first oxygen ion pump current (IP1), wherein the second measuring chamber (120) is connected to said first measuring chamber (110) and wherein both measuring chambers are disposed in a solid electrolyte, the oxygen content in the second measuring chamber (120) is determined; the oxygen content is additionally determined by a separate device; the two values characterizing the oxygen concentration are compared and a defective sensor is then suggested if the oxygen concentration value determined in the second measuring chamber (120) deviates from the oxygen concentration value determined by the separate sensor device by a predeterminable magnitude.Type: GrantFiled: October 29, 2010Date of Patent: March 19, 2013Assignee: Robert Bosch GmbHInventor: Torsten Handler
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Publication number: 20130032493Abstract: A sensor for continuous detection of one or more analytes in a liquid flow, comprising an array of electrodes together forming an essentially planar sensing surface and a flow distributor with a flow inlet a flow channel and a flow outlet in order to establish a liquid flow of analytes along the sensing surface. The flow inlet and the flow outlet are located in a plane different to the plane of the sensing surface. The array of electrodes is arranged so that, in the direction from the flow inlet to the flow outlet, the array of electrodes consecutively comprises a first blank electrode, at least one measuring electrode, a second blank electrode, at least one measuring electrode and optionally a third blank electrode.Type: ApplicationFiled: December 22, 2010Publication date: February 7, 2013Inventors: Anton Karlsson, Anders Carlsson, Gerhard Jobst
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Patent number: 8287706Abstract: A laminated gas sensor element including a detection element including a solid electrolyte body having a pair of electrodes formed thereon laminated together with a heater element. A porous protection layer is formed on at least a distal end portion of the laminated gas sensor element which is to be exposed to a gas to be measured. The surface of the porous protection layer has 10 or more small pores each having a diameter of 1 ?m to 5 ?m inclusive and an aspect ratio of 0.5 to 2.0 inclusive within an area measuring 50 ?m×50 ?m, and one to less than 20 large pores each having a diameter of 8 ?m to 20 ?m inclusive and an aspect ratio of 0.5 to 2.0 inclusive within an area measuring 100 ?m×100 ?m. Also disclosed is a method for manufacturing the laminated gas sensor.Type: GrantFiled: August 31, 2010Date of Patent: October 16, 2012Assignee: NGK Spark Plug Co., Ltd.Inventors: Tatsuhiko Muraoka, Masaki Mizutani
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Patent number: 8105539Abstract: Chemical sensors whose active element exhibits both a visual change in color and a measurable change in electrical resistance when exposed to an analyte to which it selectively reacts are provided. These sensor have several unique features including vastly improved stability measured in years, irreversible visual changes and surprisingly reversible electrical changes. The combined unique features enable a new generation of ultra low power alerting, alarming and readout devices for hydrazines and other strongly reducing chemicals.Type: GrantFiled: August 21, 2007Date of Patent: January 31, 2012Assignee: KWJ EngineeringInventors: William J. Buttner, Joseph R. Stetter
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Patent number: 8097138Abstract: The present invention provides oxygen partial pressure control apparatuses that can control the partial pressure of oxygen in atmospheric gases in processing apparatuses or the like to within the range of 0.2 to 10?30 atm, while maintaining low material and operational cost conditions.Type: GrantFiled: May 19, 2005Date of Patent: January 17, 2012Assignee: National Institute of Agrobiological SciencesInventors: Naoki Shirakawa, Shinichi Ikeda, Katsuhide Uchida
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Patent number: 8083927Abstract: In vitro analyte sensors and methods of analyte determination are provided. Embodiments include sensors that include a pair of electrodes to monitor filling of the sample chamber with sample.Type: GrantFiled: May 8, 2009Date of Patent: December 27, 2011Assignee: Abbott Diabetes Care Inc.Inventors: Yi Wang, Benjamin J. Feldman, Jared L. Watkin
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Publication number: 20110210752Abstract: A system and method for voltammetric analysis of a liquid sample solution.Type: ApplicationFiled: August 24, 2010Publication date: September 1, 2011Applicant: TRACEDETECT, INC.Inventors: Vladimir Dozortsev, William T. Dietze
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Publication number: 20110203941Abstract: A sensor includes a sheath that is elongated along a longitudinal axis; a spacer positioned within the sheath and defining first and second channels having lengths that extend along the longitudinal axis; a first elongated member positioned within the first channel; and a second elongated member positioned within the second channel. The first elongated member includes an active surface forming a working electrode and the second elongated member including an active surface defining a counter electrode.Type: ApplicationFiled: August 28, 2008Publication date: August 25, 2011Applicant: Pepex Biomedical LLCInventor: James L. Say
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Patent number: 7943023Abstract: The present invention is directed to devices and methods for carrying out and/or monitoring biological reactions in response to electrical stimuli. A programmable multiplexed active biologic array includes an array of electrodes coupled to sample-and-hold circuits. The programmable multiplexed active biologic array includes a digital interface that allows external control of the array using an external processor. The circuit may monitor, digitally control, and deliver electrical stimuli to the electrodes individually or in selected groups.Type: GrantFiled: September 10, 2007Date of Patent: May 17, 2011Assignee: Gamida for Life B.V.Inventors: Richard Gelbart, Don L. Powrie, Paul David Swanson
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Publication number: 20110100811Abstract: The invention relates to an electrochemical sensor including a housing with a chamber containing an electrolyte, at least one measuring electrode for oxygen detection, at least one counter electrode and at least one reference electrode, wherein the sensor has a two-part diffusion barrier, wherein a first part of the barrier forms a labyrinth with a second part of the barrier disposed between the measuring and the counter electrode.Type: ApplicationFiled: May 7, 2009Publication date: May 5, 2011Applicant: MSA Auer GmbHInventors: Rolf Eckhardt, Martin Weber
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Patent number: 7887682Abstract: In vitro analyte sensors and methods of analyte determination are provided. Embodiments include sensors that include a pair of electrodes to monitor filling of the sample chamber with sample.Type: GrantFiled: March 29, 2006Date of Patent: February 15, 2011Assignee: Abbott Diabetes Care Inc.Inventors: Yi Wang, Benjamin J. Feldman, Jared L. Watkin
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Patent number: 7857963Abstract: To provide an electrode plate for electrochemical measurements that enables detecting and quantifying the concentration of a target substance contained in a sample solution with rapidity and favorable sensitivity using an apparatus for electrochemical measurements is objected to.Type: GrantFiled: January 7, 2010Date of Patent: December 28, 2010Assignee: Panasonic CorporationInventors: Hidehiro Sasaki, Hiroaki Oka
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Patent number: 7725148Abstract: A thin film sensor, such as a glucose sensor, is provided for transcutaneous placement at a selected site within the body of a patient. The sensor includes several sensor layers that include conductive layers and includes a proximal segment defining conductive contacts adapted for electrical connection to a suitable monitor, and a distal segment with sensor electrodes for transcutaneous placement. The sensor electrode layers are disposed generally above each other, for example with the reference electrode above the working electrode and the working electrode above the counter electrode. The electrode layers are separated by dielectric layer.Type: GrantFiled: September 23, 2005Date of Patent: May 25, 2010Assignee: Medtronic Minimed, Inc.Inventors: Rajiv Shah, Rebecca K. Gottlieb
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Patent number: 7699966Abstract: Methods and devices for point of care determination of heparin concentration in blood are described. Cartridges including protamine ion sensitive electrodes (ISEs) and reference electrodes and systems for automatically determining heparin concentration in the cartridges are provided. Some systems add blood to a protamine bolus sufficient to bind all heparin, leaving excess protamine. The excess protamine concentration can be determined by measuring the initial slope of the electrode potential rate of change, and comparing the slope to known protamine concentration slope values In some cartridges, an oscillating pressure source moves the blood-protamine mixture back and forth across the protamine ISE. Some systems also use a second blood sample having the heparin removed or degraded to create a blank reference sample. Protamine ISEs can include polyurethane polymer, DNNS ionophore, and NPOE plasticizer.Type: GrantFiled: May 11, 2005Date of Patent: April 20, 2010Assignee: Medtronic, Inc.Inventors: Wei Qin, Daniel S. Cheek, Christopher Hobot, Kelvin Bonnema, Randy Meyer, Douglas Dean Nippoldt, Vitally G. Sitko, Qingshan (Sam) Ye, Narayanan Ramamurthy
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Patent number: 7638035Abstract: An object of the invention is to provide an electrode plate for electrochemical measurements for detecting with high sensitivity and determining a substance included in a living body. The electrode plate of the present invention has on both faces of body of the substrate, oxidation electrode and reduction electrode opened respectively at upper layer opening and lower layer opening having the same area; and further has a plurality of through-holes that penetrate through from the face of the oxidation electrode to the face of the reduction electrode, in which electrode pairs are formed which exhibit a redox cycle effect between the oxidation electrode and the reduction electrode by applying the potential which can proceed an oxidative reaction of a reductant on the oxidation electrode, and the potential which can proceed a reductive reaction of an oxidant on the reduction electrode.Type: GrantFiled: January 30, 2009Date of Patent: December 29, 2009Assignee: Panasonic CorporationInventors: Hidehiro Sasaki, Akio Oki
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Patent number: 7635422Abstract: An electrode plate for electrochemical measurements capable of measuring the concentration of a target substance included in a sample solution with favorable accuracy and high sensitivity is provided. The electrode plate for electrochemical measurements of the present invention includes a substrate, an upper layer, a lower layer, a first electrode body sandwiched between the substrate and the upper layer, and a second electrode body sandwiched between the substrate and the lower layer, wherein: the upper layer has a plurality of upper layer through-holes; the first electrode body has a plurality of first electrodes exposed from via the upper layer through-hole in the first electrode body; the substrate has a plurality of substrate through-holes; and the second electrode body has a plurality of second electrodes exposed via the upper layer through-hole and the substrate through-hole in the second electrode body.Type: GrantFiled: May 6, 2009Date of Patent: December 22, 2009Assignee: Panasonic CorporationInventors: Hidehiro Sasaki, Hiroaki Oka