Abstract: A sterile container system for the sterile transport and storage of medical, in particular surgical instruments and/or implants during a sterilization process, includes a closable sterile container which is formed by a lid and a trough, and at least one sieve cage which can be inserted therein, at least one fastening device being present which acts, on the one hand, on one of the medical instruments which can be inserted in the sieve cage, immobilizing the instrument on the sieve cage, and at the same time acts on the sieve cage, immobilizing the latter on the sterile container.

Abstract: A package assembly for a drug reconstitution assembly includes a body, a drug reconstitution assembly and a removable lid. The body includes a plurality of protrusions configured to mate with a plurality of corresponding features of the drug reconstitution assembly to inhibit axial and rotational translation of the drug reconstitution assembly and its constituent parts during shipping and handling. By preventing axial and rotational shifting during shipment, premature and accidental puncture or contamination of the medication or the spikes within the drug reconstitution assembly is minimized.

Abstract: The presently disclosed debris collection system includes an elongate body having a first end, a second end, and a bore extending therethrough. The first end of the elongate body is hermetically closed while the second end has an opening. The elongated body is made of an impermeable material. A cap fixed to the elongated body and has a bore extending therethrough. A port, which is attached to the cap, is designed for introducing fluid into the elongated body. A watertight seal, such as a gasket, is attached to the cap. The seal is also made of an impermeable material. In operation, a liquid is introduced into the debris collection system. A surgical tool must then be introduced into the system. Thereafter, a vortex is created within the system to debride debris from the surgical tool.

Abstract: A kit for the storage and transportation of medical equipment (31) following processing or use thereof contains, as its principal component, a tray (10) defined by a base (12) and surrounding walls (13, 14). The tray (10) has at least one fold line (19) formed in the base and/or walls (13, 14), thereby to facilitate compaction of said tray (10) for disposal. Optional further components of the kit include: a tray line (28); a protective cover (34) adapted to be detachably secured to the tray (10); a lid (23) adapted to engage with the walls (13, 14) of the tray (10); and an oxygen-impermeable container (37) adapted to receive said tray (10) therewithin.

Abstract: A vapor hydrated packaged catheter assembly and method of manufacturing and distributing same includes a gas impermeable package housing a catheter within a catheter-receiving cavity. The catheter assembly has a hydrophilic coating applied to at least a portion of the outer surface of a catheter tube or shaft which may be surrounded by a sleeve to provide a no-touch, sure grip feature. The catheter assembly is disposed within the catheter receiving cavity of the package together with a limited amount of a vapor donating liquid provided as a source of vapor to activate the hydrophilic coating. The amount of vapor donating liquid is less than the amount that would otherwise be sufficient to cause a spill hazard. It may be loose liquid as a desired percentage of the volume of a tube-receiving portion of the catheter receiving cavity of the package, or it may be contained in a liquid sequestering element.

Abstract: The invention is a protective package for delivering a medical or dental implant to an implantation site. The protective package protects the implant from contact with any surfaces from which bacteria or other contaminants could be transferred to the implant itself. The protective package is adapted to allow the implant to be delivered to the implantation site and to allow the primary retention of the implant in a bone or other type of tissue to be carried out before completely removing the implant from the protective packaging.

Abstract: A system for vacuum loss indication includes a rigid inner container, a flexible outer container, a sliding block, and a bias mechanism. The rigid inner container includes a receptacle with an open proximal end and a closed distal end. The flexible outer container surrounds the inner rigid container and includes a semi-transparent portion. The sliding block is within the receptacle and visible through the semi-transparent portion and includes a pressure indicator. The bias mechanism biases the sliding block to a first position under a first level of vacuum and a second position under a second level of vacuum. A first portion of the pressure indicator is visible through the semi-transparent portion in the first position and a second portion is visible through the semi-transparent portion in the second position.

Abstract: A cartridge shipping aid is provided to retain staples within staple pockets of a staple cartridge during shipment. The cartridge shipping aid includes a base and a longitudinal rib extending perpendicularly from an underside of the base and indiscernible into a knife slot formed in a staple cartridge. One or more perpendicular keys are formed along a lower edge of the longitudinally extending rib for engagement with an underside surface of the staple cartridge. The cartridge shipping aid may additionally include sidewalls projecting perpendicularly from outer edges of the base. Projections are formed on one end of the base for engagement with associate detents formed on the staple cartridge. Grasping structure is formed adjacent one end of the base and longitudinal rib.

Abstract: A resilient single-dose sachet for storage and administration of a liquid medication. The sachet includes a top portion, a bottom portion, and a perimeter, the top portion having a narrowed region; a front layer and a back layer. The front layer and back layer are permanently joined around the perimeter to form around the perimeter to form a seal and the seal forms a compartment. The compartment is adapted to contain the liquid medication. The sachet can be adapted such that the user can consume the liquid directly from the sachet.

Abstract: An eye protection kit comprises a plurality of soft, smooth eye patches and an atomizer providing ultraviolet radiation protection for use while sunbathing or in a tanning bed is herein disclosed stored within a carrying case. The eye patches are each comprised of a textile material comprising reinforced perimeters. For personal comfort and to maintain moisture, the patches are wetted with a cooling fluid therefrom the atomizer. Further, the patches would be oversized, thus providing shielding to areas adjacent to the eye where skin lines often form and shielding below the eyes where sunbathers sometimes develop unflattering skin discolorization.

Abstract: Packaging for catheter treatment devices, such as catheters including multi-electrode arrays, are disclosed herein. In one embodiment, for example, a catheter package assembly comprises a tray, a lid, and a coiled sheath disposed in the tray. The tray includes at least one pocket adapted to receive a distal end portion of a catheter. The tray and lid each include cooperative latching features. The sheath defines a lumen that is configured to receive an elongate shaft of the catheter.

Abstract: This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution including sugar and non-ionic surfactant.

Abstract: This invention relates to prophylactic and/or therapeutic application of microorganism species that are, for example, administered orally as delayed release formulation designed to release its microbial content to the distal small intestine and/or colon in high quantities and density, which is a “normalized” approach to repopulate the colonic flora as a method of prevention and/or treatment of, for example, Clostridium difficile colitis.

Abstract: A container holds at least one surgical implement, has a lock mechanism, and has a signature label that impedes access to the surgical implement until the correct surgical site is confirmed. A method of using the container includes the steps of confirming the correct surgical site, signing the label and removing it from the container, placing the label in the medical record, unlocking the container, removing the implement, and beginning the surgery, wherein the surgical team is forced to pause to confirm the correct surgical site before starting the surgery. Preferably, the container top may be removed and placed between the surgeon and surgical technician to define a no-hands “neutral zone” to avoid being stuck by the sharps. Also, the container preferably includes compartments for storing used sharps and/or a local anesthetic-loaded syringe, and the top may be replaced and secured for safely disposing of the sharps after the surgery.

Abstract: A system of surgical instruments for use with at least a first implant and a second implant of the same type but different sizes is provided. The system includes a first container containing at least a first surgical instrument of a first type that is size specific and a second surgical instrument of a second type that is size specific; a second container containing at least a third surgical instrument of the first type and a fourth surgical instrument of the second type, wherein both the third and fourth instruments are of a second size that is different from the first size and that corresponds to the second implant; and a third container containing at least a fifth surgical instrument of a third type that is size independent.

Abstract: A method of cleaning and coating at least one surface of a container for storing a medicament or other ingestible non-pharmaceutical product, the method comprising the steps of using a water-based cleaning composition in conjunction with a water-based crosslinked acrylic resin containing coating material. The process makes the cleaning and coating technology consistent with present environmental regulations and workplace safety requirements, including control of emissions of volatile organic compounds (VOCs). Further, the concentration of extractible organic compounds has been reduced to the lowest practical level. The process is also applicable to other substrates where it is desired to have low-extractable organics and high adhesion of the subsequently applied coating.

Abstract: The present invention generally relates to compositions and methods for transdermal drug delivery. The compositions can be used in a variety of applications, including treating erectile dysfunction or sexual dysfunction, treating wounds, or causing or promoting hair growth. For example, in one aspect, the present invention is generally directed to compositions for delivery of nitric oxide, transdermally and/or to a mucosal surface. The composition may include nitric oxide. The nitric oxide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. In some embodiments, a composition comprising nitric oxide is unexpectedly stable and can be stored long-term.

Abstract: Provided are a thermoplastic elastomer composition comprising: 100 parts by mass of (a) a hydrogenated block copolymer that is a hydrogenated product of a block copolymer containing (A) a polymer block containing a structural unit derived from an aromatic vinyl compound and (B) a polymer block containing a structural unit derived from isoprene or a mixture of isoprene and butadiene, having a total content of a 3,4-bond unit and a 1,2-bond unit of 45% or more, has a peak top molecular weight (Mp) obtained by gel permeation chromatograph in terms of polystyrene standard of from 250,000 to 500,000, and is in a form of powder having a bulk density of from 0.10 to 0.40 g/mL; from 10 to 300 parts by mass of (b) a softening agent; and from 5 to 200 parts by mass of (c) a polyolefin resin, and a molded article and a sealing material for medical use each comprising said thermoplastic elastomer composition.

Abstract: Medication dispensers are provided that are both child-proof and tamper evident. In one embodiment, a child-proof and tamper-evident dispenser includes a tray member comprising a plurality of receptacles for receiving a pharmaceutical compound, a stop tab connected to a first peripheral edge by a neck member, and a tab member at a second peripheral edge that is opposite from the first peripheral edge. The dispenser further includes a bottom case body and a top case body configured to form an enclosure around the plurality of receptacles when brought into a substantially confronting relationship. Each of the bottom case body and the top case body include a sloped wall member having a shelf portion that surrounds the neck member when the enclosure is formed. A plurality of locking tabs engage a complimentary number of locking recesses configured to receive an end portion of the locking tabs to fix the bottom case body and the top case body in an enclosure configuration.

Abstract: The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron. The formulations are particularly useful in the preparation of intravenous and oral liquid medicaments.

Abstract: Use of an isolated peptide comprising an amino acid sequence being no more than 25 amino acids in length, the amino acid sequence comprising at least one aspartate or a homolog thereof, the peptide having an Insulin-Degrading Enzyme (IDE) inhibitory activity, for the manufacture of a medicament identified for treating a disease selected from the group consisting of diabetes, obesity, hyperglycemia, retinal damage, renal failure, nerve damage, microvascular damage and varicella-zoster virus (VZV) infection is disclosed.

Abstract: This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of freezing liquid solutions of the solute by the top and the bottom of the solution simultaneously. The as frozen solution then provides a lyophilized cake of the solutes with large and uniform pores.

Abstract: The present disclosure relates to a package for a surgical repair kit, the package including at least a first area configured and dimensioned to receive a surgical mesh and a second area configured and dimensioned to receive an implantable plug.

Abstract: An inflatable cuff may be adapted to seal a patient's trachea when associated with an endotracheal tube. Packaging and transporting of these cuffs while inflated may provide for decreased wrinkles and thereby improved sealing of the trachea. Provided is a package for a medical device with an inflatable region, comprising a substantially non-stretchable region that substantially conforms to the shape of the inflatable region of the medical device when the inflatable region is inflated.

Abstract: An object of the present invention is to provide a packaging material that is capable of long term storage by preventing adsorption or transfer of an easily oxidizable component and an oily component in an adhesive of a patch to the packaging material, and also preventing discoloration and decrease in drug effect due to oxidization. The present invention provides the packaging material for a patch including: an inner layer made of polyethylene terephthalate having heat sealing properties; an oxygen-absorbing layer that includes an oxygen-absorbing resin having an unsaturated alicyclic structure as an oxygen-absorbing part; and an oxygen barrier layer made of aluminum foil as an outer layer.

Abstract: Diaper packaging having a reduced manufacturing cost may be created by bagging stacks of diapers and bundling the bags. Bands may be applied circumscribing the bundled bags of diapers. One band may be applied along a first direction perpendicular with the length of the stacked diapers. A second band may applied in a second direction parallel with the length of the stacked diapers. The bags of diapers may include several stacks of diapers, and the bundles may include several bags of diapers. For certain bundle configurations of packaged diapers, additional bands may be placed circumscribing the bundles for improved stability. Packaging by banding bundles of diapers may also be used to package other personal care articles and absorbent articles.

Abstract: A transdermal drug delivery device is disclosed for administering an oxidizably and/or hydrolyzably degradable drug, e.g., cholinesterase inhibitors such as rivastigmine. The device comprises a) a substantially impermeable backing layer; b) an adhesive layer substantially free of antioxidant and containing a therapeutically effective amount of the degradable drug, which adhesive drug-containing layer is capable of adhering directly to a subject's skin or to another adhesive layer which is capable of adhering to a subject's skin; and c) a substantially impermeable protective release liner layer which releasably contacts the adhesive drug-containing layer or another adhesive layer. The delivery device is sealed in a degradation protective packaging system, such as a substantially oxygen impermeable heat sealable plastic pouch that contains a substantially inert gas and/or a degradation protectant material for the drug, such as an antioxidant, which can be inserted separately to the pouch.

Abstract: Packaging for prosthetic heart valves including an assembly for stabilizing dry prosthetic tissue implants such as heart valves during storage. The packaging assembly includes a primary sterile barrier that permits gas sterilization of the tissue implant, and a secondary sterile barrier that also prevents oxidation of the implant during long-term storage. Tissue heart valves may be placed or suspended within a cavity of an inner rigid tray with a gas-permeable lid sealed thereon, and a cap placed over the cavity to limit movement of the valve therein. The inner tray is placed within an outer sterile barrier, such as another rigid tray or a flexible pouch, and the assembly is then sterilized. The outer sterile barrier may include a double seal so that a first gas-permeable seal can be closed for sterilization, after which a second gas-impermeable seal can be closed to seal out any further oxygen contact with the tissue implant.

Abstract: A nebulizer kit includes a case body, a flow channel formation member that covers an opening of the case body, an outside air introduction tube erected vertically from a base surface of the flow channel formation member and including a long groove formed in an inner circumferential surface thereof, a compressed air introduction tube below the outside air introduction tube within the case body and extending toward the interior of the outside air introduction tube, and an atomizing area formation member. The atomizing area formation member includes a liquid suction tube formation portion, a baffle, and a baffle support portion that connects the liquid suction tube formation portion and the baffle and that extends toward a side area of the baffle from an outer surface of the liquid suction tube formation portion. The baffle support portion is contained within the long groove of the outside air introduction tube.

Abstract: A container (200) is configured to retain a coiled device, such as a guide wire, within the container (200). The container (200) includes a bowl (201) and one or more retention devices (230). Each retention device (230) includes a retention tab (206) that is coupled to the bowl (201) by a hinge (207). The bowl (201) and retention tabs (206) can be manufactured as an integral component by using living hinges as the hinge (207). The containers (200) are configured to be efficiently stacked when the retention tabs (206) are rotated to an open position.

Abstract: A bone infusion apparatus for interbody grafts includes a container; a retainer, the retainer including a recess for receiving therein bone graft material; and a lid including a plunger assembly. A method of preparing bone including cadaver bone for use in cervical fusion includes: placing cadaver bone combined with bone collected from a patient into a recess of the retainer; placing the retainer in the container; filling the container with a liquid; attaching a lid the container; depressing a plunger of the lid such that a press head advances toward the retainer causing a dynamic pressure to act on the cadaver bone combined with the bone collected from the patient; suctioning the liquid from the container; removing the combined bone from the retainer; and placing the combined bone removed from the container into a vertebral interspace of the patient.

Abstract: A cartridge holder for retaining a cartridge comprising a distal end and a proximal end being spaced apart from one another in the direction of an axis, an interior which is suitable to receive and retain a cartridge in a cartridge retaining section of the interior, and a main part and at least one protrusion which is moveably connected to the main part. The protrusion is arranged to define the radial extension of a subsection of the interior, wherein the subsection is arranged at an axial position which is further away from the distal end than the cartridge retaining section. Furthermore, the protrusion is arranged to vary the radial extension of the subsection when the protrusion is moved with respect to the main part. Moreover, a method for securing a cartridge in a cartridge holder is proposed.

Abstract: The present disclosure generally relates to tissue engineering and wound healing. More particularly, the present disclosure relates to the modification of plasma with a stability conferring agent to create a hydrogel for use in regenerative medicine and other tissue engineering applications.

Abstract: A cartridge for holding surgical fasteners includes a base having a plurality of upstanding walls, adjacent pairs of walls defining spaces for holding surgical fasteners, at least one surgical fastener securing member movably connected to the base and movable relative to the base from an open position wherein fasteners can be loaded into the spaces, and a closed position wherein fasteners in the spaces are covered and held in the spaces, and a locking structure engageable between the base and the surgical fastener securing member for locking the surgical fastener securing member in the closed position.

Abstract: The invention relates generally to materials for facilitating the administration of dimethyl sulfoxide (DMSO) and related compounds. In one embodiment, the invention comprises a kit comprising items used for the safe and effective administration of DMSO. In another embodiment, the invention relates to indicating containers for holding or delivering DMSO.

Abstract: A compressed article of hygiene is formed by a compressed cloth that has been compressed by dehydration or vacuum pressure into a coin shape and that is expandable upon contact with a liquid, and a plurality of microencapsulated beads containing a material. The microencapsulated beads are attached and embedded in the compressed cloth. Upon contact with water, expansion of the compressed cloth is unconstrained, and the compressed cloth when expanded has a shape of a facial mask with openings for eye, nose and mouth. The material is a facial treatment material that hardens upon drying.

Abstract: A nebulizer kit includes a case body, a flow channel formation member that covers an opening in an upper area of the case body, and a cylindrical aerosol discharge port that passes through a portion of the top surface of the flow channel formation member located toward the outer edge thereof. The case body and/or the flow channel formation member includes a rotation mechanism that, when the case body has overturned and the aerosol discharge port has become positioned on the lower side in the vertical direction of the top surface of the flow channel formation member, causes the case body to rotate in a circumferential direction to cause the aerosol discharge port to move away from a lower side in the vertical direction. Even if the nebulizer kit has overturned, a liquid within the nebulizer kit is prevented from spilling.

Abstract: An exemplary system for crimping a prosthetic valve comprises a radially expandable and compressible prosthetic valve, a crimping device positioned around the valve and configured to reduce the diameter of the valve to a delivery configuration, and a sterile package enclosing the valve and the crimping device. The valve can be pre-assembled in a partially crimped configuration within the crimping device. After removing the sterile packaging, the crimping device can be used to crimp the valve from the partially crimped configuration to the delivery configuration, such as by twisting a knob on the crimping device. The system can further comprise at least a portion of a delivery catheter within the sterile package, wherein the valve is pre-mounted on or adjacent to an inflatable balloon of the delivery catheter, such that the valve can be crimped onto the delivery catheter using the crimping device.

Abstract: Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals.

Abstract: A medical assembly, preferably a sterilized one, includes a medical article (5) and a package containing the article, the package including a hollow support element (2) inside which the article (5) is free, a first protective element (3), called a stopper, which can be coupled to the support element (2) of the article, such that the support element (2) has a grip part (20) that protrudes from the stopper (3), and a second hollow protective element (4), called a cover. The cover can be coupled to the stopper (3) in such a way as to delimit, in cooperation with the stopper (3), a chamber (8) inside which there extends the grip part (20) of the support element, and, in the state when the cover is coupled to the stopper, a part of the stopper (3) protrudes from the cover (4).

Abstract: The invention relates to a web-form packaging material which comprises at least one layer, comprising a packaging material surface, of a sealable material, to a packaging unit with a transdermal therapeutic system and with a packaging material of this kind, and also to a process for producing a packaging unit. For this purpose, at least the abovementioned surface of the packaging material has a multiplicity of recesses and/or a multiplicity of non-recessed regions. The distance between two adjacent recesses and/or the distance between two adjacent non-recessed regions is less than five times the packaging material thickness. Moreover, the depth of the recesses is not less than 1.2 nanometers and not more than 95% of the packaging material thickness. With the present invention, the sticking of an adhesive on the inner face of the packaging material is effectively prevented.

Abstract: Discrete consumer products, such as sterilization wraps and methods for producing such discrete consumer products are disclosed. Sterilization wraps of the present disclosure avoid contacting exterior, non-sterile surfaces of sterilization wraps with the sterile contents of the sterilization wrap. Spring elements are coupled with the sterilization wrap to urge the sterilization wrap from a closed to an open position when desired. In this manner, the sterilization wrap avoids being re-introduced to the sterile equipment contained in the sterilization wrap.

Abstract: A storage apparatus is provided. The storage apparatus defines a storage cavity having an opening at the upper surface of the storage apparatus with a substantially planar flange extending outwardly from the opening of the storage cavity and defines a plurality of support structures, each support structure (a) having an opening at the upper surface of the storage apparatus and (b) adapted to support the storage apparatus.

Abstract: A matrix material comprising a pharmaceutical composition printed on the surface is described. In one embodiment the pharmaceutical composition comprises thrombin. A method for making the matrix material with a pharmaceutical composition printed on the surface is also described. The matrix material can be used for promotion of hemostasis and/or wound healing. A kit-of-parts comprising a matrix with a pharmaceutical composition and a container with a peelable lid is described.

Abstract: Reduced-pressure canisters and methods for recycling are disclosed. In one instance, a method for performing multiple reduced pressure treatments on one or more patients includes providing a reduced-pressure treatment system that includes a first canister body, a fluid reservoir, and one or more modules, such as a pump control module. The method involves using the reduced-pressure system and then removing one or more modules and placing the one or more modules in fitted shipping receptacle that disallows shipping of the fluid reservoir. The one or more modules may be reconditioned and coupled to a second canister body. Other systems and methods are disclosed.

Abstract: An implantable device is provided. The device is constructed from an open body containing electronic components, a heat-sensitive component, and a sealing component. The device is formed in a moisture controlled environment, such that the heat-sensitive component is attached to the open enclosure after the enclosure has been heated. The sealing component is subsequently affixed to the open enclosure to form a sealed enclosure.

Abstract: A supporting structure for concurrently holding a plurality of cylindrical containers for substances for medical, pharmaceutical or cosmetic applications is provided. The supporting structure includes a supporting base having a plurality of receptacles, which are configured such that the containers can be inserted into the associated receptacles, wherein the receptacles extend in the longitudinal direction of the containers and are configured to hold side wall portions of the containers at least partially clamped. The receptacles are continuous side walls, wherein the opening widths of the receptacles can be adjusted by a coordinated adjustment of the side walls of the receptacles between a first position, in which the containers can be inserted into the receptacles, and a second position in which the containers are clamped. The bottoms or upper ends of the containers are exactly fixed at a given height despite tolerances.

Abstract: A supporting structure is provided that concurrently supports a plurality of containers for substances for medical, pharmaceutical or cosmetic applications. The supporting structure includes a planar supporting base having a plurality of openings, which are disposed in a regular array configuration, and an associated holding device that supports the plurality of containers in a positive-fit manner at the supporting base. The holding device protrudes from a bottom side of the supporting base and is configured to support the plurality of containers in the positive-lit manner at their upper rim. Additionally, receptacles are provided on an upper side of the supporting base opposite to the bottom side for accommodating containers at the upper side of the supporting base.

Abstract: A multifunction medicine chest includes a chest, a door set at one side of the chest to open and close the chest and a control device. The chest is configured to store medicines and includes a plurality of drawers. Each drawer corresponds to one category of medicines. The control device includes an input unit, a storage unit, and a control unit. When a user stores a medicine into the chest, the input unit obtains medicine information of the medicine and transmits the medicine information to the control unit, the control unit determines the category of the medicine and a number of the drawer for the medicine and generates storage information of the medicine. When the user takes the medicine out of the chest, the input unit obtains portion medicine information of the medicine, the control unit searches for the storage information.

Abstract: A package in the form of a bag containing a medical product, in particular for use in the regenerative treatment of cartilage damage in humans or animals, the package having a component preferably in the form of a port, to fill the package with a liquid, preferably a cell-containing liquid.