Abstract: The present invention relates to a pharmaceutical composition comprising an active core comprising duloxetine or its pharmaceutically acceptable derivatives, a separating layer comprising a pH modifier and a gastro-resistant coating comprising a gastro-resistant polymer selected from methacrylic acid copolymers and optionally an over-coating layer. The present invention also relates to a process for the preparation of duloxetine hydrochloride. It also relates to a packaged medicament.

Abstract: The present invention relates in general to cartridges for storage and processing of pre-formulated food materials, and methods and apparatus for processing the food materials stored within such cartridges. More particularly, the present invention relates to a unique, fully recyclable food cartridge, comprising an annular cylindrical container within which the pre-formulated food material is sealed for storage and cooking, an integral burst disk, a discharge die located above the burst disk and a sensory device with information for controlling the thermo-mechanical processing of the food materials stored within such food storage cartridge by the method and apparatus.

Abstract: Compositions and methods are disclosed for stabilizing glycerin-in-oil emulsions, which can be used to significantly reduce thermal instability or instability over time compared to traditional cosmetics or topical formulations. The compositions comprise one or more oil-soluble rheological modifiers and optionally one or more emulsifiers in a glycerin-in-oil emulsion.

Abstract: Nitric oxide releasing compositions, which comprise nanoparticles having an exterior surface comprising solid amorphous silica, the exterior surface having nitrosothiol-containing groups attached thereto, the nanoparticles being dispersible in an aqueous system, devices including the compositions, and methods of making and using the compositions and devices are disclosed.

Abstract: According to one embodiment, a system comprises a container and an oxygen sorbing closure operable to close an opening of the container. The closure comprises an oxygen sorption layer, an oxygen permeable layer, and a removable oxygen impermeable layer. When the oxygen impermeable layer is removed, the oxygen sorbing closure is operable to sorb oxygen molecules from a headspace of the container.

Abstract: The process of the invention for the preparation of products, in particular cellulose-containing products (1) and spaces includes the arrangement of at least one flavour and/or fragrance (3) and/or active substance, bound in a solid carrier material, in and/or at the product (1) and/or the direct proximity of the cellulose-containing product (1) and/or the space. Furthermore, means are provided for the preparation of products, in particular cellulose-containing products, and of spaces as described, as well as systems from these means and products, in particular cellulose-containing products.

Abstract: Thermoplastic polyolefin polymer compositions, polymer chips, fibers, woven or nonwoven fabrics, films, closures, and laminates include a polymer and cyclodextrin compound with a volatile maturation inhibitor or an olefinic ethylene receptor antagonist in respiring produce materials. The polymer composition can also include a cyclodextrin-modified polymer or a substituted cyclodextrin. Olefinic ethylene inhibitors can be formed in the cyclodextrin composition, wherein the cyclodextrin releases the olefinic inhibitor composition when used in produce packaging materials. Coating compositions can also be made. The inhibitor is introduced into the materials and is released under controlled conditions of humidity. Upon release, the olefinic inhibitor blocks ethylene receptor sites on proteins that control maturation and can produce an extended period during which the produce does not substantially complete maturation or ripening to a degree leading to spoilage.

Abstract: Single use, substrate uniformly impregnated with an anhydrous illuminating skin brightener solution for the use of aseptically delivering a single dose of an illuminating skin brightener solution to the area of discoloration. Solution and substrate is contained encapsulated within a heat sealed foil enclosure that is stable for at least five years.

Abstract: A biodegradable jar has an enclosure wall with a cap that form ajar that holds a semi-solid material. In order to prevent the biodegradable wall from being weakened by the semi-solid material in the jar, both an exterior surface and an interior surface of the wall and the cap include a permeation barrier material that substantially prevents the semi-solid material from seeping through the walls of the jar. The enclosure wall could have an inner wall that is shorter than the outer wall which forms a ledge that a separate cover for the semi-solid material could rest upon.

Abstract: Disclosed is a large round bale wrapped with a protective covering for permitting it to be stored outside. The covering is constructed of one or more layers of semi-permeable material. It is possible for an additional layer to be added to a region of the baler to be placed on the ground during storage, this additional layer resulting in the covering becoming essentially non-permeable in the region of the additional layer. A baler for applying the covering to a bale is disclosed together with a device for placing a visual marker on the bale so as to aid a person handling a discharged bale in knowing where the region covered with the additional layer of material is located so that this region may be manipulated into ground contact for storage.

Abstract: The present invention innovates with a device that enables storage of baby food powder, with the device having at least one connector enabling the device to be connected to a box of baby food powder, for example, as a cover, with the device being composed of at least two separable or fixed parts, which are enabled by rotating on their axis, in such way as the interior of the device that connects the two parts is hollow in part of its area, and thus enables pouring of the powder from the storage box, through the attachment, which is a part of the device attached to it, and which connects to the upper part of the device, and serves as a measuring unit as needed, and can be replaced with other measuring units, based on the user's needs and requirements. Optionally, the device can also be attached to the openings of baby bottles, where at least one storage compartment is used to store the baby food powder.

Abstract: Tumors are identified as responsive to treatment with anti-HER2 antibodies by detecting the presence of a HER2/HER3 and/or HER2/HER1 protein complex or for HER2 phosphorylation in a sample of tumor cells. Patients suffering from a tumor comprising HER/2/HER1 and/or HER2/HER3 heterodimers and/or HER2 phosphorylation are treated with anti-HER2 antibodies, such as rhuMAb 2C4.

Abstract: A packaged product. The package has a plastic container and a light-sensitive liquid composition contained in the plastic container. The container has a plastic container for protecting a light-sensitive liquid composition from light. The container has: i) a top; ii) a bottom opposing to the top; iii) a first layer extending from the top to the bottom, wherein the first layer is non-opaque; and iv) a second layer superposed with a part of the first layer, wherein the second layer has a blocking agent. The container has a non-superposed area covering the bottom. In the non-superposed area the first layer is not superposed with the second layer. The non-superposed area has a height h from about 2 mm to about 50 mm.

Abstract: A packet (1) of washing machine detergent is disclosed, in the form of a non-woven fabric bag, possibly pre-treated to act as a dye absorber, containing a pre-measured amount of powder product comprising detergent proper with the addition of at least one among the following substances: sanitiser, perfume, descaler and bleach.

Abstract: An arrangement having a plurality of moistened cosmetic pads based on nonwovens which are piled into a closable packaging container in order to distribute to the final consumer and to prevent evaporation. The pads have, on average, a moisture content of at least 200% of the dry weight thereof in the arrangement, the pads have a fiber structure made of staple fibers, are individually moistened and have a homogeneous moisture content such that the difference of the average moisture content of the pads which are arranged in the upper and in the lower quarter of the stack is, at a maximum, 30% of the average moisture content of all of the pads.

Abstract: A container for molten metal includes an outlet for outflow of the molten metal from the container and a temperature measuring device fixed in a wall of the container. The temperature measuring device includes a plug, an outer protective sheath having a closed end, and an inner protective tube having a closed end. The inner protective tube is arranged within the outer protective sheath. A thermocouple is arranged within the inner protective tube. The plug includes a substantially refractory material and the outer protective sheath consists essentially of substantially refractory metal oxide and graphite. The outer protective sheath extends away from the first end of the plug and projects into a recessed portion of the wall of the container. The closed end of the outer protective sheath is arranged in the recessed portion. A junction of the thermocouple is proximate to the closed end of the inner protective tube.

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system with respectively one separating element separating the two chambers from one another in a magazine, which accommodates the at least one dual-chamber system. The magazine is arranged in a container sealed with a closure element. The method additionally includes feeding the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; closing the first chamber with a gas-permeable closure element; and freeze drying the solution contained in the first chamber. The method further includes closing the first chamber with a closure element; filling a second chamber of the at least one dual-chamber system; closing the second chamber; and discharging the container from the clean room.

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

Abstract: The present invention relates to phenyloxyaniline derivatives, to methods of their production and to uses thereof.

Abstract: A dosimeter is disclosed for use in container including outer walls defining an interior volume, the dosimeter including: a radon detection element adapted to detect a radon level for the interior volume; a neutron detection element adapted detect a neutron level for the interior volume. The dosimeter is adapted to measure the radon level and neutron level for a period of time, compare the measured radon level to a first threshold, compare the measured neutron level to a second threshold, and determine information indicative of the presence or absence of fissile material within the interior volume based on the comparisons.

Abstract: Oral care compositions containing agents that are effective for treating and modifying teeth and mucosal surfaces to be hydrophobic are disclosed. Hydrophobic modification of teeth and other oral cavity surfaces imparts a variety of end use benefits including prevention of caries, erosion, wear, staining, sensitivity and desquamation as well as providing shine, smoothness and positive tooth feel benefits. The compositions contain selected surface active organophosphate compounds that deposit and adhere to teeth and other oral cavity surfaces forming a hydrophobic coating having prolonged retention thereon. By forming a “hydrophobic coating” on the oral cavity surface is meant that the hydrophobic character of the surface is increased as measured, for example, by an increase of at least about 10 degrees in the water contact angle of the surface after treatment.

Abstract: A compound having the general the general structure I is provided: (Formula I), wherein Z is a substituent selected from a group consisting of S and O; X is a substituent selected from a group consisting of Cl, Br, I, OH and NH2; each of R1 and R2 is a substituent independently selected from a group consisting of H, a linear, cyclic or branched, substituted or unsubstituted C1-C6 alkyl, a substituted or unsubstituted aryl, and a substituted or unsubstituted heteroaryl; and each of Y and Y1 is a substituent independently selected from a group consisting of H and C(O)—C6H4—Br.

Abstract: A packaged mineral fibre insulating material has: a) a Recovered Thickness of at least 95% nominal thickness; and b) an Ordinary Parting Strength of at least 95 g/g; and c) a Weathered Parting Strength of at least 75 g/g the material comprising mineral fibres and an organic, formaldehyde free binder in a quantity of less than 15% by weight, preferably less than 10% by weight, said binder having been applied to the fibres of the insulating material in liquid form at pH of greater than 5.

Abstract: The invention concerns a packaging film comprising or consisting of a layer system with a barrier layer preventing oxygen penetration, an adhesion improvement layer adjacent to the barrier layer and an oxygen scavenger layer adjacent to the adhesion improvement layer. The invention also concerns a packaging, a packaging-packed product unit and the use of a packaging film.

Abstract: A container for holding a grout sample, said container having five walled sides, and one open side, wherein one walled side defines a base of the container and the open side provides access to a cavity, said cavity bounded by four walled sides and a floor defined by said base; and grout placed within said cavity.

Abstract: A kit is disclosed that includes a first component comprising alginate, wherein the first component is comprised in a first sterile vial, and a second component comprising cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected from the group consisting of GM-CSF, VEGF, KGF, bFGF, TGF?, angiopoietin, EGF, IL-I?, IL-6, IL-8, TGF?, and TNF?, wherein the cells are allogeneic and mitotically inactive, a buffered solution, and human serum albumin or a cryoprotectant, wherein the second component is comprised in a second sterile vial.

Abstract: Embodiments of the invention are directed to hygienic devices to control the spread of airborne viruses and bacteria emanating from coughing or sneezing. In one embodiment, the hygienic device is a cough and sneeze arrestor in the form of a “coughing cup.” The coughing cup may incorporate one or more filters with a plurality of apertures of varying sizes and/or no apertures. In some embodiments, the filters may be embedded or infused with a microbicide such as an antibacterial or viricide. The filters may be pre-attached within the coughing cup at certain predetermined locations. The coughing cup may have one or more recesses to accommodate the nose and/or a chin of a person when using the coughing cup.

Abstract: Disclosed are films obtained from blends of ethylene copolymers with organic acid salt-modified potassium ionomeric copolymers. The films of the present invention can be welded using RF energy.

Abstract: The invention relates to novel polyvinyl alcohol (PVA) gels which gelate in situ and are suitable for nucleus (gel bodies of the intervertebral disks) replacement, and to a process and to an apparatus for administration thereof, to the use thereof and to a vessel which comprises an inventive PVA gel.

Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.

Abstract: Methods of reclaiming plastic from infectious medical waste and manufacturing medical devices from reclaimed plastic are described. Medical devices made from plastic reclaimed from infectious medical waste are also described.

Abstract: Compositions provided by mixing a biotin-containing component and an avidin-containing component are useful as an adhesive or sealant for medical/surgical uses.

Abstract: [Object] An adhesive preparation containing donepezil is provided in which adhesive layer discoloration over time is inhibited. [Solution] The adhesive preparation containing donepezil has an adhesive layer containing donepezil and an acrylic adhesive on at least one side of a support, and a water content of the adhesive layer is 1000 ppm or more. The water content of the adhesive layer is preferably 8000 ppm or less and more preferably 7000 ppm or less.

Abstract: The present invention provides a container, comprising: a cavity provided with a first opening portion; a pressure buffer area which is positioned above the cavity and the first opening portion and which is provided with a second opening portion corresponding to the first opening portion; and a thin film channel which extends through the first opening portion and the second opening portion and which has an inner channel wall and an outer channel wall, wherein the inner channel wall forms a passage for fluids with an inlet end and an outlet end, the inlet end being positioned outside the second opening portion of the pressure buffer area with a first opening and closing structure and the outlet end being positioned inside the cavity, and wherein the second opening portion is hermetically connected to the outer channel wall while the first opening portion is hermetically connected to the outer channel wall except for the area of at least one directing hole formed therebetween, such that a fluid under pressure f

Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.

Abstract: The invention relates in some aspects to compositions, e.g., wipes, e.g., sanitary wipes, infant wipes, etc., comprising a bamboo fiber and a isolated essential oil, and methods of use thereof.

Abstract: A method for removing submicron colloidal particulates, such as hydrocarbons, from water. The method includes first adding a soluble, cationic polymer, such as chitosan, a salt, or solution of chitosan to water containing the submicron particulates and a halogenating agent, followed by adding a soluble, anionic polymer or anionic salt to the water. The resulting flocs are filtered to remove the submicron particulates.

Abstract: Buffer solutions within a plurality of containers can be adjusted and controlled by exposing the containers while open to a controlled environment. In particular, an inventory of containers holding bicarbonate buffers can be adjusted to a precisely controlled pH by exposing the containers while open to a controlled carbon dioxide environment in a treatment chamber.

Abstract: A multiwipe package having enhanced wipe storage stability is disclosed. The wipe package contains a stack of wipes in a barrier packaging film, wherein the headspace in the package between the stack of wipes and the packaging film is minimized.

Abstract: The present disclosure provides a container containing reference solution for clinical chemistry, whereby the container includes a closure part-covered outlet at which reference solution can be removed by puncturing with a puncturing element. The disclosure further provides a wick that is soaked with the reference solution and arranged in the container to extend from the outlet and such that a majority of its length extends into an interior space of the container.

Abstract: Affords a method of storing GaN substrates from which semiconductor devices of favorable properties can be manufactured, the stored substrates, and semiconductor devices and methods of manufacturing the semiconductor devices. In the GaN substrate storing method, a GaN substrate (1) is stored in an atmosphere having an oxygen concentration of 18 vol. % or less, and/or a water-vapor concentration of 12 g/m3 or less. Surface roughness Ra of a first principal face on, and roughness Ra of a second principal face on, the GaN substrate stored by the storing method are brought to no more than 20 nm and to no more than 20 ?m, respectively. In addition, the GaN substrates are rendered such that the principal faces form an off-axis angle with the (0001) plane of from 0.05° to 2° in the <1 100> direction, and from 0° to 1° in the <11 20> direction.

Abstract: Pregnancy-associated glycoproteins (PAGs) are structurally related to the pepsins, thought to be restricted to the hoofed (ungulate) mammals and characterized by being expressed specifically in the outer epithelial cell layer (chorion/trophectoderm) of the placenta. By cloning expressed genes from ovine and bovine placental cDNA libraries, the inventors estimate that cattle, sheep, and most probably all ruminant Artiodactyla, possess possibly 100 or more PAG genes, many of which are placentally expressed. The PAGs are highly diverse in sequence, with regions of hypervariability confined largely to surface-exposed loops. Selected PAG that are products of the invasive binucleate cells, expressed highly in early pregnancy at the time of trophoblast invasion and expressed weakly, if at all, in late gestation are useful in the early diagnosis of pregnancy. In a preferred embodiment, the invention relates to immunoassays for detecting these PAGs.

Abstract: Ready-to-use foamable pesticide compositions that contain a particulate pesticide suspended therein and applicators for dispensing such compositions. Methods for treating pests such as arthropods by contacting pests with such compositions are also provided.

Abstract: Binders to produce or promote cohesion in non-assembled or loosely assembled matter.

Abstract: The invention is directed to a paraffin wax contained in a thermoplastic polymer packaging material which is meltable along with the paraffin wax.

Abstract: The present invention teaches a method for separating a fat component of a fluid-fat mixture extracted from a patient. More particularly, the method of invention places a sponge formed of a fluid-absorbing material, such as polyvinyl acetal, in contact with the mixture so as to absorb the fluid component, thereby separating the fat component of the mixture. The separated fat component can then be injected into a selected body portion of the patient.

Abstract: A sterile device immersed in a sterile buffer and a method for providing same. The sterile device may be a medical device such as a biosensor having a biomolecule as a sensing element such as, for example, a glucose oxidase enzyme. The buffer may be a bicarbonate solution. Both the device and the buffer may be packaged and stored over long term while maintaining sterilization. The sterilization method may comprise a combination of gaseous, liquid and light sterilization.

Abstract: A plurality of pellets include at least one of a synthetic, biomass, mineral, or polymer based material. The pellets can have a specific gravity of about 0.01 to about 0.3 g/cm3 and are dimensionally stable, substantially dust-free, substantially non-hygroscopic, and resistant to settling and compression.

Abstract: A container for a non-irradiated nuclear fuel assembly including a single casing for receiving at least one nuclear fuel assembly, the casing being formed from an elongate tubular shell, the shell including a metallic internal layer delimiting at least one individual housing for receiving a nuclear fuel assembly, and a metallic external layer surrounding the internal layer, the shell being filled between its internal layer and its external layer, and from lids for closing the or each housing at the longitudinal ends of the shell.

Abstract: A novel class of antimicrobial polymeric agents which are designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.