Magnetic Patents (Class 210/222)
  • Patent number: 11167290
    Abstract: An apparatus for treating a stream of contaminated water having an elevated concentration of at least one of light metals, heavy metals, sulfates that includes at least one process fluid inlet communicating with a process conduit; at least one electrode reaction vessel in fluid communication with the process conduit, the reaction vessel having an interior chamber and at least one electrode positioned in the reaction chamber, the electrode powered by a alternating current source; and at least one magnetic field reaction vessel in fluid communication with the process conduit, the magnetic field reaction vessel having an outwardly oriented surface and an opposed inwardly oriented surface, the magnetic field reaction vessel having at least one magnet in contact with the inwardly oriented surface of the magnetic field reaction vessel.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: November 9, 2021
    Assignee: Tygrus, LLC
    Inventor: Lawrence Carlson
  • Patent number: 11154798
    Abstract: Provided is a magnetic filtration apparatus with a simple structure for permitting easy and effective discharge of magnetic substances from the inside of a flow passage to its outside, the magnetic substances being captured by attraction from a liquid to be treated by magnetic separation. The magnetic filtration apparatus includes a treatment container 12 having an inlet 26 and outlet 28 of the liquid, and a discharge port 36 of the separated magnetic substances. A magnetic apparatus 20 attached around the treatment container 12 attracts the separated magnetic substances to an inner wall of the treatment container 12, while cancellation of the effect of the magnetic field generated by the magnetic apparatus 20 allows the attracted magnetic apparatus to flow into a detachable collecting container 14 positioned below the treatment container 12, due to the gravity, through a communication passage 15.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: October 26, 2021
    Assignee: Maeda Shell Service Co., Ltd.
    Inventor: Tatsuhiro Maeda
  • Patent number: 11112415
    Abstract: Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid. In some cases, the systems employ an assay consumable comprising a plurality of assay sites. The systems, devices, and/or methods, in some cases, are automated. In some cases, the systems, devices, and/or methods relate to inserting a plurality of beads into assay sites, sealing assay sites, imaging assay sites, or the like.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: September 7, 2021
    Assignee: Quanterix Corporation
    Inventors: David Fournier, Todd Campbell, Cheuk Kan, John Lawson, Andrew Rivnak, Michael Kagan, David C. Duffy
  • Patent number: 11110469
    Abstract: A magnetic separator includes a housing defining a product flow path, a drawer moveable between a first position and a second position, a magnet operatively connected to the drawer, the magnet positioned within the product flow path when in the first position and the magnet withdrawn from the flow path when in the second position, and a stripper plate frame attached to the housing. A stripper plate is fixed to the stripper plate frame that conforms with the magnet and through which the magnet passes as the drawer is moved between the first and second positions. An anti-rotation mechanism includes a slot that engages along a length of a shoulder such that. When the anti-rotation mechanism is positioned having the slot over the shoulder, the magnet is prevented from moving from the axially locked position. The shoulder extends beyond an outer surface of the anti-rotation mechanism.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: September 7, 2021
    Assignee: Magnetic Products, Inc.
    Inventor: Ronald Kwasniewicz
  • Patent number: 11097964
    Abstract: A magnet positioning system for positioning magnets inside pipes includes a first stackable paddle that includes slots for accepting magnets and a second stackable paddle that includes a metal component for attracting the magnets and securing the magnets in the slots when the paddles are stacked together. Once stacked together, the paddles are inserted into position inside a pipe and the metal component is removed to release the magnets which move toward, and attach to, the inside wall of the pipe. A fluid conduit is positioned between the magnets using a spacer and a fixing agent permanently secures the magnets, fluid conduit, and spacer in place.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: August 24, 2021
    Inventor: Mark K. Page
  • Patent number: 11084045
    Abstract: The invention relates to a magnetic matrix for high intensity magnetic separator which is fed with a pulp containing magnetic and non-magnetic particles, the magnetic matrix (8) comprising a series of grooved metal plates (7) on both sides thereof, the grooved plates being arranged in rows parallel to and spaced apart from each other from the same spacing (6) within a housing, each face of each metal grooved plate (7) having the ridges aligned with the valleys of the face facing it of the grooved plate (7), and a corrugated expanded sheet (12) is disposed at each spacing (6) between adjacent grooved plates (7), with corrugations of the corrugated expanded sheets (12) accompanying the ridge-valley alignments of the respective grooved plates (7).
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: August 10, 2021
    Inventor: Jose Pancracio Ribeiro
  • Patent number: 11047845
    Abstract: This disclosure relates to verifying the operation of cell analyzers, including microscope-based cell imaging and counting analyzers. In one general aspect, a mixture of micro-beads having known characteristics is introduced into the analyzer. One or more images of the mixture are acquired with the analyzer's microscope, the images are analyzed, and a determination is made about whether results meet one or more predetermined quality control thresholds. Also disclosed is a hematology control material that can be used to perform the verification and includes a solvent, a dye dissolved in the solvent, and micro-beads suspended in the solvent. In another general aspect, a quality control method for the analyzers includes capturing images of samples that include patient cells using at least a microscope, extracting sample-specific information about properties of the patient samples from the images, and testing information from the samples against predetermined standards to verify the operation of the analyzer.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: June 29, 2021
    Assignee: Medica Corporation
    Inventors: Donald E. Barry, Jr., Lindsay Goetz
  • Patent number: 11014095
    Abstract: A magnetic filter for a central heating or cooling system comprises a pipe having an inlet end and an outlet end, and a filtration portion between the inlet and outlet ends the diameter of the filtration portion of the pipe being greater than the diameter of the inlet end of the pipe and also greater than the diameter of the outlet end of the pipe, and a magnet assembly adapted to be attachable to the pipe, around an outside surface of the filtration portion of the pipe, and movable relative to the pipe from a position close to the pipe to a position more distant from the pipe.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: May 25, 2021
    Assignee: ADEY HOLDINGS (2008) LIMITED
    Inventor: Simon Downie
  • Patent number: 11008628
    Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: May 18, 2021
    Assignee: Labrador Diagnostics LLC
    Inventors: Elizabeth A. Holmes, Timothy Smith, Samartha Anekal, James R. Wasson, Daniel L. Young, Chinmay Pangarkar
  • Patent number: 10978376
    Abstract: Provided is a sensing device and a method for fabricating the same. The sensing device includes a first sensor including a first substrate, first electrodes, and a first passivation layer and a second sensor disposed on the first sensor and including a second substrate, second electrodes, and a second passivation layer. The second sensor is connected to the first sensor through a chemical bonding.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: April 13, 2021
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Yong Hee Kim, Sang-Don Jung
  • Patent number: 10953092
    Abstract: A device is dynamically programmable to generate at least a first magnetic field during a first time interval, and at least a second magnetic field during a second time interval thereby causing the particles exposed to the change in the magnetic field to aggregate to a target region. The device is further dynamically programmable to switch between the first and second magnetic fields for any number of cycles. Optionally, the device includes a multitude of conductors that receive a first current during the first time interval to generate the magnetic field, and a second multitude of conductors that receive a second current during the second time interval to generate the second magnetic field. The second multitude of conductors may be substantially parallel to the first multitude of conductors. A controller disposed within the device is adapted to vary the frequency of switching between the first and second magnetic fields.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: March 23, 2021
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Alex H. Pai, Seyed Ali Hajimiri
  • Patent number: 10940486
    Abstract: In at least one illustrative embodiment, an electromagnetic filter may include a transfer pipe and multiple electromagnetic filter elements positioned in an interior volume of the pipe. Each electromagnetic filter element includes a support comb, a solenoid coupled to the support comb, and multiple magnetic members arranged in a planar array positioned within an opening of the support comb. Each magnetic member may rotate about an end that is coupled to the support comb. The magnetic members may be magnetostrictive sensors and may include a biorecognition element to bind with a target microorganism. A method for fluid filtration includes coupling the electromagnetic filter between a fluid source and a fluid destination, energizing the solenoids of each electromagnetic filter elements, and flowing a fluid media through the transfer pipe of the electromagnetic filter. The fluid media may be liquid food such as fruit juice. Other embodiments are described and claimed.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: March 9, 2021
    Assignee: Auburn University
    Inventors: Bryan A. Chin, Shin Horikawa, Steve R. Best, I-Hsuan Chen, Zhongyang Cheng, Songtao Du
  • Patent number: 10934185
    Abstract: A water treatment unit with a housing having a housing interior and an oscillation unit mounted so as to oscillate in the housing interior. The oscillation unit can be set in oscillation by a coil through which an electrical alternating signal flows, wherein a water inlet and a water outlet are provided on the housing, and wherein a flow area is formed between the inner wall of the housing that delimits the housing interior and the oscillation unit, the flow area being designed such that water flowing from the water inlet to the water outlet flows around the oscillation unit.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: March 2, 2021
    Inventor: Wolfgang Schulze
  • Patent number: 10903184
    Abstract: A thermal interface material and systems and methods for forming a thermal interface material include depositing a layer of a composite material, including at least a first material and a second material, the first material including a carrier fluid and the second material including a filler particle suspended within the first material. A particle manipulator is positioned over the layer of the composite material, the particle manipulator including at least one emitter to apply a particle manipulating field to bias a movement of the filler particles. The second material is redistributed by applying the particle manipulating field to interact with the second material causing the second material to migrate from a surrounding region in the composite material into a high concentration region in the composite material to form a customized thermal interface such that the high concentration region is configured and positioned corresponding to a hotspot.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: January 26, 2021
    Assignee: International Business Machines Corporation
    Inventors: Jonathan Fry, Tuhin Sinha, Michael Rizzolo, Bassem M. Hamieh
  • Patent number: 10828414
    Abstract: In vivo and ex vivo positionable magnetic filtration devices are provided that magnetically filter one or more therapeutic agents conjugated to a magnetic particle in blood flowing in a blood vessel.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: November 10, 2020
    Assignee: The Regents of the University of California
    Inventors: Marc C. Mabray, Steven W. Hetts, Prasheel V. Lillaney, Aaron D. Losey, Caroline D. Jordan, Sravani Kondapavulur, Andre M. Cote
  • Patent number: 10828636
    Abstract: The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: November 10, 2020
    Assignee: FANNIN PARTNERS LLC
    Inventors: Leo Linbeck, III, Michael John Heffernan, Dev Chatterjee, Atul Varadhachary
  • Patent number: 10809256
    Abstract: The purpose of the present invention is to provide a simple measurement tool which can rapidly measure various chemical substances contained in environments or from inside a living body by a simple or inexpensive means/method.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: October 20, 2020
    Assignee: KAZUSA DNA RESEARCH INSTITUTE FOUNDATION
    Inventors: Osamu Ohara, Ken Nonaka
  • Patent number: 10807028
    Abstract: Disclosed is an apparatus for removing air and particles, such as dirt, from a fluid which includes, inter alia, an elongated pressure vessel that has a vessel wall that defines an interior chamber and a vertical axis for the apparatus. Inlet and outlet ports are formed in the vessel wall, the inlet port allowing fluid to enter the interior chamber and the outlet port allowing conditioned fluid to exit the interior chamber of the pressure vessel. A plurality of concentrically arranged cylindrical mesh screen elements are positioned within the interior chamber that release entrained air from the fluid entering the interior chamber. Additionally, a cylindrical tube is positioned within the concentrically arranged mesh screen elements for removing particles from the fluid entering the interior chamber. In certain embodiments the apparatus includes a magnetic particle collector.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: October 20, 2020
    Assignee: AMTROL LICENSING INC.
    Inventor: Michael Cogliati
  • Patent number: 10786762
    Abstract: The present invention relates to a removal device for removing gas bubbles and/or dirt particles from a liquid in a liquid conduit system or for removing a second liquid from a first liquid in the conduit system. The removal device includes a main channel for a main flow, the main channel having an entry and an exit which are configured to be connected to the conduit system, a housing which defines an inner space, at least one supply channel extending from the main channel to the inner space, at least one return channel extending from the inner space back to the main channel, directly or indirectly via a return chamber, at least one quiet zone in the inner space in which in use the liquid has a substantially smaller velocity than in the main channel. The quiet zone is configured to allow dirt particles or a relatively heavy liquid to settle at a lower end of the housing and/or gas bubbles or a relatively light liquid to rise to an upper end of the housing.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: September 29, 2020
    Assignee: Flamco B.V.
    Inventor: Jan Henk Cnossen
  • Patent number: 10787958
    Abstract: The present invention refers to a system, a method and a device to optimize the efficiency of the combustion of gases for the production of clean energy comprising a magnetic nucleus (30) and inlet and outlet ducts (41a, 42a), the inlet and outlet ducts (41a, 42a) being configured to receive gases, the gases alternately establishing flows between the inlet ducts (41a) and the outlet ducts (42a) and vice-versa, the magnetic nucleus (30) being configured to generate and to expose the gases within the inlet and outlet ducts (41a, 42a) to magnetic fields (35), the alternation of flows between the inlet and outlet ducts (41a, 42a) and the exposure to magnetic fields (35) promoting acceleration of the hydrogen atoms and ions of oxygen and argon, promoting the reduction of the radii of the orbits of the electrons of the hydrogen around their nuclei and provoking the release of potential energy of the electrons and corresponding increase of the kinetic energy of the nuclei of the gas molecules, in such a way to optim
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: September 29, 2020
    Assignee: The Bluedot Alliance B.V.
    Inventor: Marcelo Fernando Pimentel
  • Patent number: 10782223
    Abstract: A device for separating a sample of cells suspended in a bio-compatible ferrofluid is described. The device includes a microfluidic channel having a sample inlet, at least one output, and a length between the sample inlet and the at least one output, wherein a sample can be added to the sample inlet and flow along the length to the at least one outlet. The device includes a plurality of electrodes, wherein the microfluidic channel length transverses the plurality of electrodes, and further includes a power source for applying a current to the plurality of electrodes to create a magnetic field pattern along the length of the microfluidic channel. The present invention also includes a method for separating at least one cell type.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: September 22, 2020
    Assignee: YALE UNIVERSITY
    Inventor: Hur Koser
  • Patent number: 10751728
    Abstract: A cutting fluid intelligent recycling device, comprises a frame, a first-level filtering device, second-level filtering device, and clean liquid tank installed on the frame; the first-level filtering device being provided with a dirty fluid tank used for containing liquid, the dirty fluid tank having a dirty fluid suction device and dirty fluid treatment device; through the first-level and second-level filtering devices, the cutting fluid intelligent recycling device can remove the cuttings, iron powder, floating oil stain, cenobium, floccule and impurities in the cutting dirty fluid and also sterilize and deodorize the cutting fluid coolant to prolong its service life.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: August 25, 2020
    Assignee: DONGGUAN XUNMEI ENVIRONMENTAL PROTECTION TECHNOLOGY, INC
    Inventor: Jian Feng
  • Patent number: 10751861
    Abstract: A power tool including a motor and a pulse unit intermittently driving an output shaft, wherein the pulse unit includes a cylinder with an inner cavity arranged to withhold a hydraulic fluid, and an anvil located inside the inner cavity, the anvil being connected to the output shaft, wherein: at least one recess is arranged inside the inner cavity wherein at least one magnet is provided inside the recess; and the at least one recess is deeper than the at least one magnet such that a pocket is formed in the recess outside the magnet.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: August 25, 2020
    Assignee: ATLAS COPCO INDUSTRIAL TECHNIQUE AB
    Inventors: Per Thomas Söderlund, Niclas Mikael Wiklund, Hans Niklas Öberg
  • Patent number: 10724930
    Abstract: Sandwich separation is based on forming a sandwich complex with a magnetic bead, buoyant bead, and a target. Once a sandwich formation is created, the sandwich can be separated using its dual physical properties, namely magnetism and buoyancy. Sandwich separation is highly specific, allows for removal of the beads that do not have any attached target, and reduces the number of background beads. Sandwich separation can also be used to allow for target detection in raw specimen. Also, improvement of detection capability is accomplished by performing AMBR measurements on a solid interface, where the rotational period speeds up and allows for dramatically reduced time-to-result.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: July 28, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Brandon H. McNaughton, Paivo Kinnunen, John G. Younger
  • Patent number: 10702811
    Abstract: A filter device for fluids includes a housing (1) accommodating a filter element (5). The housing has an inlet (47) for the supply of fluid to be purified to a non-filtrate chamber (49) of the housing (1) and has an outlet 42 for the filtrate. The non-filtrate chamber is separated from a filtrate chamber (46) of the housing (1) by the filter medium (33). A magnetic field-generator unit (57) is arranged inside the non-filtrate chamber (49). An adhering surface a sleeve or casing (51) attracts ferromagnetic particles by a magnetic force effect. In the non-filtrate chamber (49), the sleeve (51) extends outside of the respective filter element (5) parallel to the inlet (47) and transversely to the outlet (42). The non-filtrate chamber (49) at least partially encompasses the outlet (42) at the point of transition to the filtrate chamber (46).
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: July 7, 2020
    Assignee: HYDAC PROCESS TECHNOLOGY
    Inventors: Markus Olschok, Christian Schindler, Alexander Schwarzkopf
  • Patent number: 10677695
    Abstract: For collecting magnetic particles, there is used a magnetic material including a plurality of magnets that are arranged in contact one with another in parallel to a direction of magnetization in such a manner that south and north poles of adjacent magnets are reversed alternately or a magnetic material having at least one peak of a magnetic force in a magnetic pole surface, and the peak magnetic force is 600 gausses or more.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: June 9, 2020
    Assignee: LSI Medience Corporation
    Inventors: Atsushi Koyata, Takaaki Sorin
  • Patent number: 10670436
    Abstract: Provided here are systems and methods to determine the flow rate of fluids that have magnetizable components. One such flow rate measurement apparatus contains a magnetization unit that magnetizes fractions of magnetizable components present in the fluid; a magnetic field detector with a probe to detect the magnetic field associated with the magnetized fractions of the fluid; and a processing circuitry to determine velocity of the fluid from time taken for the magnetized fractions to travel from the magnetization unit to the magnetic field detector and the distance between the magnetization unit and the magnetic field detector. Flow rate of the fluid is then subsequently determined from the velocity and the cross-sectional area of the conduit of the flow measurement apparatus. Various other embodiments may be disclosed and claimed.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: June 2, 2020
    Assignee: SAUDI ARABIAN OIL COMPANY
    Inventor: Juan D. Escobar
  • Patent number: 10626030
    Abstract: Electromagnetic processing of fluid materials is disclosed. Separation of one or more ionic components of a fluid, and combination of one or more ionic components in a fluid, are discussed.
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: April 21, 2020
    Inventor: Anthony J. Orler
  • Patent number: 10618828
    Abstract: An apparatus for reducing and inhibiting scale formation in water conduits is disclosed. The scale reducing apparatus has at least two stages, each stage containing one or more conduits therein surrounded by magnets. The magnets form a strong, substantially uniform magnetic field in the conduit(s) which is substantially perpendicular to the flow of water therein. Dissolved ions in the water interact with the magnetic field and may as a result be forced into contact with one another to form one or more non-dissolvable solids. The reduction in dissolved ions reduces and/or inhibits the formation of scale in the water supply lines of a structure, thus increasing the life of the conduits, appliances, and other structures where scale may form.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: April 14, 2020
    Assignee: AKWAMAG, PBC
    Inventor: Tuyen Long Vo
  • Patent number: 10618057
    Abstract: An apparatus for treating a stream of contaminated water having an elevated concentration of at least one of light metals, heavy metals, sulfates that includes at least one process fluid inlet communicating with a process conduit; at least one electrode reaction vessel in fluid communication with the process conduit, the reaction vessel having an interior chamber and at least one electrode positioned in the reaction chamber, the electrode powered by a alternating current source; and at least one magnetic field reaction vessel in fluid communication with the process conduit, the magnetic field reaction vessel having an outwardly oriented surface and an opposed inwardly oriented surface, the magnetic field reaction vessel having at least one magnet in contact with the inwardly oriented surface of the magnetic field reaction vessel.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: April 14, 2020
    Assignee: Tygrus, LLC
    Inventor: Lawrence Carlson
  • Patent number: 10613104
    Abstract: An assay to determine anticoagulants in a blood or blood plasma sample, wherein the assay comprises analyses with at least two wet chemistry prothrombine time (PT) methods. The assay comprises measuring PT in a first reaction mixture with a first PT method and measuring PT in a second reaction mixture with a second PT method, wherein the concentration of blood or blood plasma in the second reaction mixture differs from the concentration of blood or blood plasma in the first reaction mixture. The PT methods are calibrated to give the same or approximately the same PT results for reference samples which lack anticoagulants of interest for the assay. Further, calculating a difference in PT from the measurements, wherein if the difference in PT is 1) significant, this is indicative of a presence of anticoagulants in the sample, or 2) non-significant, this is indicative of an absence of anti-coagulants above detectable level in the sample.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: April 7, 2020
    Assignee: ZAFENA AB
    Inventor: Mats Ranby
  • Patent number: 10555427
    Abstract: An electronic device with a magnetically attached electronic component is described herein. An electronic device includes a housing and an electronic component. The electronic component is positioned within the housing and magnetically attached to an internal surface of the housing via a magnetic force between the electronic component and the internal surface of the housing. During manufacturing, the electronic component can be magnetically attached to the internal surface of the housing by aligning one or more magnetic attachment points of the electronic component within magnetic proximity to one or more corresponding magnetic attachment points of the internal surface of the housing of the electronic device to magnetically attach the electronic component to the internal surface of the housing.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: February 4, 2020
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Kanth Kurumaddali, Kenneth Charles Boman, David John Huston, Han Li
  • Patent number: 10545139
    Abstract: A method for retrieving magnetic components from a sample solution includes obtaining an array plate with a sample surface that includes a plurality of sample regions and a surrounding region. A first solution is located on a sample region of the plurality of sample regions. The first solution includes a plurality of magnetic components. A separation layer that includes one or more protrusions is placed so that at least a respective protrusion of the one or more protrusions is at least partially immersed in the first solution. A first magnetic device is placed within the respective protrusion. At least a portion of the plurality of magnetic components is retrieved from the first solution by concurrently moving the separation layer and the magnetic device so that the respective protrusion ceases to be at least partially immersed in the first solution on the sample region.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: January 28, 2020
    Assignee: Curiox Biosystems Pte Ltd.
    Inventors: Namyong Kim, Hanwen Melvin Lye, Kong Leong Cheng
  • Patent number: 10533170
    Abstract: A magnetic particle manipulation method for magnetic particle comprises the steps of; subjecting magnetic particles and a magnetic solid having a larger particle diameter than said magnetic particles to existing together in a liquid layer, and moving said magnetic solid and said magnetic particles in said liquid layer by a magnetic field manipulation. According to one aspect of the present invention; a manipulation method for magnetic particles comprising the steps of; moving magnetic particles in a first liquid layer into a gelled medium layer by a magnetic field manipulation in a device, wherein gelled medium layers and liquid layers are in-place alternately in a container, moving said magnetic particles present in the gelled medium into a second liquid layer by the magnetic field manipulation; and moving said magnetic particles along with said magnetic solid in the second liquid layer.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 14, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Tetsuo Ohashi, Yukio Oikawa
  • Patent number: 10532363
    Abstract: A magnetic separation device for immunoassay using a two-sided plate for multi-well microplate separation via a flat side containing a magnetic block and a back side of magnetic microplate structure containing a matrix of permanent magnets. The present invention relates to a multi-purpose magnetic separation device that has two sides of magnetic separation function. The flat side of magnetic separation device includes magnetic block, metal or plastic sheet surface top and a pin to secure the assay plate. The back side of magnetic separation device is a multi-well structure that includes a plurality of permanent magnets placed in the spaces between the adjacent wells. There are different magnetic configurations for the multi-well structure, which ensures that each well is pulled by at least one strong permanent magnet.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: January 14, 2020
    Inventors: Kang Yao, Nan An, Khanh Duc Huynh
  • Patent number: 10500595
    Abstract: A status monitoring system includes a filter cap operatively connected to a filter housing having an inlet port and an outlet port. A magnet is affixed to the bottom side of the filter cap and extends down into the filter housing. A first thermistor is embedded in the magnet and physically isolated from the fluid for measuring the lagging temperature of the fluid due to the insulating effect of the filtered magnetite surrounding the magnet, while a second thermistor is placed inside the filter housing for measuring the temperature of the fluid. A difference between the measured temperatures, ?t, is then determined. When the ?t reaches a pre-determined point, the status monitoring system would send notification to its user and inform the user to perform the maintenance work on the magnetic filters.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: December 10, 2019
    Assignee: MESTEK, INC.
    Inventor: Joseph Olbermann
  • Patent number: 10473653
    Abstract: A novel method for determining the amount of an analyte in a sample comprising an initial purification step, occurring in a first container, comprising the following steps of mixing the sample, a delipidation agent and magnetic particles coated with first analyte binding partners in the first container, incubating the mix, removing the unbound reagents from the mix, and eluting the bound analyte in an elution solution; a transferring step consisting transferring in a volume of the elution solution comprising the analyte from the first container to a second container; and a quantification step, occurring in the second container, consisting of quantifying the analyte in said elution solution.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: November 12, 2019
    Assignee: IMMUNODIAGNOSTIC SYSTEMS LIMITED
    Inventors: Jacqueline Tran, Norbert Brutt, Loic Cornaut
  • Patent number: 10473652
    Abstract: In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: November 12, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Kazuyoshi Horii, Tomoyuki Nose, Takao Fujiwara, Tatsuya Kosako
  • Patent number: 10473572
    Abstract: A method of monitoring an immunoassay comprises determining the shape of the flow edge of fluid across an immunoassay region. This allows, for example, early detection of possible errors in the test. The above methods may also be used to provide methods to improve the run conditions of a test during its development. The method may be applied to a competitive assay.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: November 12, 2019
    Assignee: ALERE TOXICOLOGY PLC
    Inventors: Timothy John Abbott, David Patrick Edward Brookes
  • Patent number: 10449551
    Abstract: A magnetic filter (10) for a central heating system is disclosed, the filter (10) including a connection assembly (12), a canister (14), and a magnetic element (16), the connection assembly (12) including an inlet (24) and an outlet (26) for connection to a central heating circuit; the canister (14) having an interior separation chamber which is fluidly connected with the inlet (24) and outlet (26) for allowing fluid to flow into the inlet (24), through the separation chamber, and out of the outlet (26); and the magnetic element (16) being removably positionable on the outside of the canister (14), the canister (14) and the connection assembly (12) forming a sealed flow path comprising the inlet (24), the interior separation chamber and the outlet (26), and the connection assembly (12) further including a closable drain outlet (28b) for draining fluid and magnetic particles from within the canister (14), internally of the magnetic element (16).
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: October 22, 2019
    Assignee: ADEY HOLDINGS (2008) LIMITED
    Inventors: Christopher Adey, Simon Downie, Robert Charles Albrow
  • Patent number: 10441950
    Abstract: A device and method are proved for transferring a target from a first location to a second location. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes transfer surface for receiving the target bound solid phase substrate thereon for transfer. The transfer surface movable between a first position wherein the transfer surface is aligned with the first location and spaced therefrom by a distance and a second position wherein the transfer surface is aligned with the second location. An alignment structure aligns the transfer surface with respect to the second location, with the transfer surface in the second position. A force is movable between an attraction position wherein the target bound solid phase substrate are drawn toward the transfer surface and a discharge position wherein the target bound solid phase substrate are free of the force.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: October 15, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David J. Beebe, Ben P. Casavant, David J. Guckenberger, Scott M. Berry
  • Patent number: 10436685
    Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: October 8, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Martin Kopp, Nenad Milicevic, Daniel Mueller, Emad Sarofim, Goran Savatic
  • Patent number: 10408891
    Abstract: A magnetic testing apparatus includes a magnet assembly with a sample path extending through the magnet assembly. The magnetic field produced by the magnet assembly defines a known, varying magnetic field profile along the sample path. A sample is moved along sample path such that the sample portion is subjected to a predetermined magnetic field ramp or magnetic field profile during a measurement period. A measurement arrangement is also provided to measure one or more properties of the sample during the measurement period, in order to test sample properties at a plurality of different magnetic fields. The apparatus may be particularly suited to magneto-optical measurements, including Magneto-Optical Kerr Effect measurements. The apparatus may be used for testing of hard disk platters.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: September 10, 2019
    Assignee: Scott Technology NZ Limited
    Inventors: Michael Graeme Fee, Oliver John Dickie
  • Patent number: 10384156
    Abstract: Filter media, including those suitable for hydraulic and/or other applications, and related filter elements and methods associated therewith, are provided. In some embodiments, a filter media described herein may include a layer (e.g., a non-woven layer) comprising a blend of glass fibers and polymeric fibers. The polymeric fibers may comprise a plurality of charged particles at least partially embedded within the polymeric fibers. In some embodiments, the layer comprising the fiber blend may result in an increased air permeability, dust holding capacity, and/or hydraulic gamma (a high ratio of air permeability to efficiency), as compared to filter media that do not include such charged particles.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: August 20, 2019
    Assignee: Hollingsworth & Vose Company
    Inventors: Elke Schmalz, Marlina Seipp, Juergen Battenfeld
  • Patent number: 10364170
    Abstract: Devices and systems for electromagnetic treatment of fluids are provided. In various embodiments, an electromagnetic fluid treatment apparatus comprises a first rod spacer, a second rod spacer, and at least one conductive rod. In various embodiments, the first rod spacer comprises a fluid pipe aperture and at least one rod aperture, and the second rod spacer comprises a fluid pipe aperture and at least one rod aperture wherein the rod aperture of the first rod spacer and the rod aperture of the second rod spacer are circumferentially aligned about a centerline axis. In various embodiments, the conductive rod comprises a first attachment portion and a second attachment portion, wherein the first attachment portion is disposed in the rod aperture of the first rod spacer, the second attachment portion is disposed in the rod aperture of the second rod spacer, and the conductive rod extends therebetween.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: July 30, 2019
    Inventor: John Robert Lersch
  • Patent number: 10322417
    Abstract: Briefly, the invention provides a method for magnetically assisting demulsification of extraction phases, the method having the steps of contacting a first solution of a first solvent and a solvated paramagnetic metal ion with a second solvent, where the second solvent is immiscible with the first solvent; mixing the first and second solutions to create an emulsion having a first phase of the first solvent and second phase comprising the second solvent where the phases of the emulsion contain different concentrations of the paramagnetic metal ion; and applying a magnetic field gradient to the first and second phases of the emulsion to accelerate separation of the first phase from the second phase. Also provided is a system for demulsifying phases used in the extraction of paramagnetic moieties from solution having a lumen with an interior region, an interior surface, and exterior surface; and a magnetic field gradient present within the interior region.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: June 18, 2019
    Assignee: UCHICAGO ARGONNE, LLC
    Inventor: Ross J. Ellis
  • Patent number: 10273560
    Abstract: Provided is a recovery method of useful resources in seawater and brine, and more particularly, a recovery method of useful resources in seawater and brine capable of improving adsorption efficiency and recovery efficiency of trace amounts of useful resources such as strontium, lithium, boron, or the like, present in brine at low cost by using a magnetic adsorbent composite and a solid-liquid separation process which uses magnetic force.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: April 30, 2019
    Assignee: KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES
    Inventors: Jungho Ryu, Hye-Jin Hong, Byoung-Gyu Kim, In-Su Park, Taegong Ryu, Kang-Sup Chung
  • Patent number: 10267871
    Abstract: Provided are magnetic sensors, which include a magnetic tunnel junction (MTJ) magnetoresistive element, a first electrode contacting at least a portion of a surface of the MTJ magnetoresistive element and extending beyond an edge of the surface of the MTJ magnetoresistive element, and a second electrode contacting at least a portion of an opposing surface of the MTJ magnetoresistive element and extending beyond an edge of the opposing surface of the MTJ magnetoresistive element, where facing surfaces of the extending portions of the first and second electrodes are non-overlapping. Also provided are devices, systems and methods in which the subject magnetic sensors find use.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 23, 2019
    Assignee: MagArray, Inc.
    Inventors: Sebastian J. Osterfeld, Shan Xiang Wang
  • Patent number: 10265457
    Abstract: A hemofilter system. In one embodiment, the hemofilter system includes a container having a first surface, a second surface, and one or more wall surfaces, the first surface, the second surface and the one or more wall surfaces defining a volume; an input port in fluid communication with the first surface; an output port in fluid communication with the second surface; a filter bed comprising a plurality of planar magnetic meshes stacked in close juxtaposition and positioned within the container volume and coplanar with the first and second surfaces; a first magnet positioned on a first surface of the container; a second magnet positioned on the second surface of the container; a first input conduit in fluid communication with the input port; and a first output conduit in fluid communication with the output port. In another embodiment, the hemofilter system includes a pump in the input conduit.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: April 23, 2019
    Assignee: MEDISIEVE LTD
    Inventors: George Charles Martin Frodsham, Quentin Andrew Pankhurst, Richard Alan Wenman, Simon Richard Hattersley
  • Patent number: 10203379
    Abstract: A method of forming a sensor array comprising a series connection of parallel GMR sensor stripes that provides a sensitive mechanism for detecting the presence of magnetized particles bonded to biological molecules that are affixed to a substrate. The adverse effect of hysteresis on the maintenance of a stable bias point for the magnetic moment of the sensor free layer is eliminated by a combination of biasing the sensor along its longitudinal direction rather than the usual transverse direction and by using the overcoat stress and magnetostriction of magnetic layers to create a compensatory transverse magnetic anisotropy. By making the spaces between the stripes narrower than the dimension of the magnetized particle and by making the width of the stripes equal to the dimension of the particle, the sensitivity of the sensor array is enhanced.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: February 12, 2019
    Assignee: Headway Technologies, Inc.
    Inventors: Po-Kang Wang, Xizeng Shi, Chyu-Jiuh Torng