Abstract: Provided herein are methods for the collection and amplification of circulating nucleic acids from a non-celluar fraction of a biological sample. Circulating nucleic acids are extracted from the non-cellular fraction and are circularized to generate single-stranded nucleic acid circles, which are then subsequently amplified by rolling circular amplification using random primers to produce an amplified library. Devices for the collection of a non-cellular fraction from a biological sample are also provided. The device includes a filtration membrane and a dry solid matrix, which is in direct contact with the filtration membrane.

Abstract: A filter element includes: a filter medium having an axis and forming an axial channel; a first and a second end plates, each end plate covering one axial end of the filter medium and being sealingly mounted on the axial end, the first end plate having an central opening coaxial and in fluid communication with the channel; the filter element being designed to be placed in a filter housing for forming a liquid filtering device, whereby a liquid to be filtered can flow along a liquid path through the filter medium towards the channel and out of the filter element through the central opening. The filter element further includes further includes a detachable plug whose position can change from an attached position to a detached position.

Abstract: Filter housings that have housing wall surface irregularities are described. The surface irregularities are positioned on the inner walls of the housings and/or axial ends of the housing walls. The surface irregularities may be, for example, grooves, ribs, bumps, and the like. The surface irregularities provide an engine integrity protection (EIP) feature by preventing non-approved replacement filter elements from forming seals against alternative sealing surfaces of the housing wall inner surfaces or axial ends.

Abstract: A filter assembly for a fresh air filtration system, the fresh air filtration system made therewith, and a method of filtering fresh air are provided. The filter assembly includes a filter housing and at least one filter element supported within the housing, the housing having at least one inlet for receiving a fluid to be filtered and at least one outlet for discharging filtered fluid, wherein the at least one inlet and at least one outlet are on a common side of the housing.

Abstract: The descriptions relate to preventing assembly of a fluid filter apparatus unless a filter cartridge is installed, and preventing assembly of a fluid filter apparatus if the incorrect filter cartridge is installed. A mechanism includes cooperation of a movable member and a structure that can move the movable member to ensure that a fluid filter apparatus cannot be completely assembled, for example connecting its filter head to its shell, when there is no cartridge installed inside the shell or when there is an attempt to install an incorrect cartridge. This can protect from an inadvertent or intentional failure to install a cartridge (or correct cartridge) in the fluid filter apparatus.

Abstract: In order to effect a seal a porous material which comprises one side of two opposing surfaces is used to restrict and evenly distribute externally pressurized gas, liquid, steam, etc. between the two surfaces, exerting a force which is opposite the forces from pressure differences or springs trying to close the two faces together and so may create a non-contact seal that is more stable and reliable than hydrodynamic seals currently in use. A non-contact bearing is also disclosed having opposing surfaces with relative motion and one surface issuing higher than ambient pressure through a porous restriction, wherein the porous restriction is part of a monolithic porous body, or a porous layer, attached to lands containing a labyrinth, the porous restriction and lands configured to not distort more than 10% of a gap created from differential pressure between each side of the porous restriction.

Abstract: An oil filter element has first and second end disks between which an annular filter medium is held. The oil to be filtered flows through the filter medium in a direction radial to the longitudinal axis of the oil filter element. The oil filter element has a central channel arranged on the clean side and provided with a central outlet opening in the region of the first end disk. A radial sealing element, formed by an elastically deformable inside circumferential section of the first end disk, is arranged in the region of the outlet opening. In addition, an axial sealing element is arranged on the outside of the first end disk. This axial sealing element is held on the first end disk by retaining elements. An oil filter having such an oil filter element is provided.

Abstract: A filter cartridge having an endplate formed of polyurethane having a varying hardness is described. A first portion of the endplate is harder than a second portion of the endplate. The first portion of the endplate helps support the filter media of the filter element and maintain the shape of the filter element. The second, softer portion creates a seal between the filter element and a filter housing when the filter element is installed in the filter housing. The first portion and separate portions may be formed from different types of polyurethane or from the same type of polyurethane having a varying composition as a function of the radial distance of the endplate.

Abstract: A fluid filter insert for a fluid filter having a filter housing, a cover and a central standpipe with a locking device preventing a closing of the cover, comprising a hollow cylindrical filter material body, two end plates enclosing said filter material body at its ends, at least one protruding member carried on the filter insert. The filter insert is configured to be placed onto the standpipe, and the protruding member of the filter insert, when the filter insert is placed onto the standpipe, is configured to actuate the locking device in an unlocking direction and allowing a complete placing of the filter insert. When the filter insert is placed onto the standpipe, the protruding member is brought into engagement with the locking device, wherein the locking device is moved in the unlocking direction by the protruding member.

Abstract: A fluid conditioning unit is provided that includes a housing, a cap, a cartridge device, and a filter cartridge. The cap is threadably secured to and unsecured from the housing by rotation about an axis of the housing. The cap forms a removable seal with the housing when secured thereto. The cartridge device is secured to the cap in a manner that restricts movement of the cartridge device with respect to the cap along the axis but allows rotation of the cartridge device with respect to the cap about the axis. The filter cartridge is removably secured to the cartridge device and is disposed in the housing along the axis.

Abstract: A filter arrangement for threadably securing to a filter head includes a housing having a surrounding wall defining an interior volume, an open mouth providing access to the interior volume and an end opposite of the open mouth. The surrounding wall has an exterior and an interior. A filter media construction is operably held within the interior volume. A sleeve, distinct from the housing, is secured to the exterior of the surrounding wall adjacent to the housing mouth and extending partially along the surrounding wall. The sleeve has an exterior and an interior. The exterior of the sleeve defines mounting threads constructed and arranged to removably mount with the filter head, when the filter arrangement is secured to the filter head. The interior of the sleeve is against the exterior of the surrounding wall. A first seal member is oriented against the sleeve to create a seal with a filter head, when the filter arrangement is secured to the filter head.

Abstract: A metal end cap seal for sealing against resent invention relates to seals within a fluid system. The metal end caps of the seal include protrusions or nibs on the terminal ends of the caps, providing for reduced friction during installation and use. The seal may also include a base elastomer and an insert elastomer, the base elastomer and insert elastomer having different material properties from one another. The insert elastomer is selected to reduce friction with a sealing surface.

Abstract: An insert block half for sealing around a cable, pipe or wire. The insert block half comprises: a body with a first and a second end, a first side intended to be arranged towards a substantially identical insert block half, and a semi-circular groove arranged in said first side and extending between the first and second end; and a reinforcement element having a shape corresponding to the shape of the semi-cylindrical groove and arranged to enclose the groove.

Abstract: The present invention generally relates to filtration, and more particularly to filter assemblies including filter housings, filter elements and safety filter elements for filtering flowing fluid such as air.

Abstract: An adsorption carrier-packed column includes a central pipe, adsorption carrier, plate A, and plate B, wherein an insertion material C is inserted between the adsorption carrier and the plate A; an insertion material D is inserted between the adsorption carrier and the plate B; the ratio of the deformation rate of the insertion material C (C1) to the deformation rate of the adsorption carrier (E0) is 1<C1/E0<10, and the ratio of the deformation rate of the insertion material D (D1) to the deformation rate of the adsorption carrier (E0) is 1<D1/E0<10; and the ratio of the thickness of the insertion material C (TC) to the distance of a gap between the adsorption carrier and the plate A (LA) is 1.1<TC/LA<4, and the ratio of the thickness of the insertion material D (TD) to the distance of a gap between the adsorption carrier and the plate B (LB) is 1.1<TD/LB<4.

Abstract: A convertible filtration system for use with cartridge filters and bag-type filters for filtering contaminated fluids comprising a filtration system housing, a base attached to the filtration system housing, and a lid mechanism for generating sealing pressure between the lid mechanism and the filtration system housing. The filtration system housing includes a basket support flange and an integral basin for accommodating both cartridge and bag-type filters. When fluid is introduced into the filtration system housing through one or more fluid inlet ports, the basket support flange and integral basin additionally serve to prevent contaminated fluids from contaminating any filtered fluids that exit the filtration system housing through one or more fluid outlet ports.

Abstract: An oil filter element has first and second end disks between which an annular filter medium is held. The oil to be filtered flows through the filter medium in a direction radial to the longitudinal axis of the oil filter element. The oil filter element has a central channel arranged on the clean side and provided with a central outlet opening in the region of the first end disk. A radial sealing element, formed by an elastically deformable inside circumferential section of the first end disk, is arranged in the region of the outlet opening. In addition, an axial sealing element is arranged on the outside of the first end disk. This axial sealing element is held on the first end disk by retaining elements. An oil filter having such an oil filter element is provided.

Abstract: The present invention relates to a filtration means (10) for the filtration of liquid media having a housing (12) and at least one filter element (16) arranged in said housing (12), wherein at least one of said filter element (16) at at least one axial end has a laterally outwardly extending flange (24), which is connected to said housing (12) forming a seal. Said flange (24) has a conical surface (25) projecting outwardly which interacts with a complementary conical surface (27) of a gasket (26) which is arranged between said flange (24) and said housing (12).

Abstract: A separation container includes a separation tube receiving a sample therein, a first sedimentation part connected to an end portion of the tube, a particle in the sample being deposited by a centrifugal or agitating force, and a separating part provided in the tube and including at least one separating layer which selectively opens and closes the tube.

Abstract: A filter cartridge 38 includes a first endcap 41 defining a first open aperture and having at least first and second protrusions extending from a wall along the aperture and into the first open aperture. The first protrusion is spaced from the second protrusion in both a vertical direction and a circumferential direction. The filter cartridge also includes filter media 44 and a second endcap 42 . The filter cartridge is mountable in a filter bowl 36 having an inner liner assembly, and the bowl and the inner liner assembly is connectable to a filter head to form a filter system.

Abstract: A crankcase ventilation system having a heat transfer conduit included therein. The system includes a housing and a crankcase ventilation filter element within the housing, the crankcase ventilation filter element configured to separate oil and oil aerosol from blow-by gases from a crankcase. An oil inlet is configured to receive pressurized oil from a component of an internal combustion engine. The conduit is positioned within the housing. The conduit is positioned along a length of the housing and is configured to carry the pressurized oil from the oil inlet to a component of the crankcase ventilation system. The conduit is configured to transfer thermal energy from the pressurized oil to the housing. An oil outlet is configured to return the pressurized oil to the crankcase.

Abstract: A sealing element for sealing a gap or joint between a support structure and a track is disclosed. The track includes a web and legs that extend vertically from the web. The sealing element includes a cover layer and an insulating strip disposed on the cover layer. The insulating strip includes a portion with a round, an oval, or a triangular cross-section.

Abstract: A composite wellbore ball valve has a spherical, fiber reinforced composite ball valve closure. The closure has an interior, central through-bore and an annular metallic sealing surface. A ball carrying assembly has an annular, metallic sealing seat surface adapted to contact and form a metal-to-metal seal with the metallic sealing surface of the ball valve closure when the ball valve closure is closed.

Abstract: A filter system is provided with a housing having a housing wall and a cover, the housing having a longitudinal axis. An inlet is arranged on the housing and feeds a fluid to be filtered into the housing. An outlet is arranged on the housing and discharges the filtered fluid. Filter elements each having at least one filter medium are arranged in the housing. At least one of the filter elements extends along the longitudinal axis. The filter medium has pleats extending along the longitudinal axis with outer and inner pleat edges. The outer pleat edges extend on the first side of the filter medium and the inner pleat edges on the second side of the filter medium and are opposite the outer pleat edges. The filter medium has a variable flow resistance along the longitudinal axis.

Abstract: A fluid filter comprising a housing, a releasable cover and a replaceable filter having a filter body and two end plates. The filter is placed on a housing standpipe which has on its free side, facing the cover, an axially displaceable endpiece. The endpiece is preloaded in the expulsion direction and in that position is blocked by a locking system against insertion which prevents the cover from connecting with the housing. An unlocking device guided by the filter unlocks the locking system and allows insertion of the endpiece. The locking system is formed by locking tabs which are radially movable, and each have a locking face facing in the axial direction. The tabs are preloaded in the locking direction and each lock the endpiece in its expelled position against axial insertion relative to the standpipe. The tabs can be radially moved into their unlocking position by the unlocking device.

Abstract: An air filter has a housing, a filter core, a resilient abutting element, a sleeve, a threaded rod bracket, a threaded rod and a nut. The axial sealing is achieved by axially compressing the resilient abutting element, such that the user does not have to apply much physical effort to compress the resilient abutting element. The user can easily push the filter core into the housing, and then rotates and tightens the nut, which can axially compress the resilient abutting element. It is easy to apply force on rotating the nut, and better still, the nut can be rotated by an electric tool, which further facilitates the convenience in assembling. Besides, the nut only abuts the sleeve, and the threaded rod bracket does not abut the filter core. Consequently, the filter core is not blocked, thereby making the air smoothly pass through the filter core.

Abstract: Described herein is a substrate including a central longitudinal axis, a first support web, and a second support web. A sinuous web may be positioned between the first support web and the second support web. The sinuous web may include transverse web portions and bridging web portions, where the bridging web portions alternatively connect ends of adjacent transverse web portions. The sinuous web may be connected to the first support web by support legs extending between bridging web portions and a surface of the first support web. The sinuous web may be connected to the second support web by support legs extending between bridging web portions and a surface of the second support web. A support leg length to distance between transverse web portions ratio may be from about 1.0 to about 4.0.

Abstract: A filter cartridge has a longitudinal axis. A cartridge housing has first and second shell portions. The first shell portion has a cartridge housing opening and an annular element retention lip which is disposed axially inward of the opening and coaxial with the longitudinal axis. The filter element has a first end cap, a second end cap, and a continuous ring of filter media disposed between the first and second end caps. The first end cap defines a fuel flow port which is coaxial with the longitudinal axis. A plurality of resilient element retention arms extend axially from the first end cap, and surround the fuel flow port. The arms terminate in retention barbs which are mateable with the annular lip. The resilient retention arms hold the retention barbs against the annular lip, suspending the filter element within the cartridge.

Abstract: A liquid filter cartridge is provided. Preferred seal arrangements are provided, to provide for preferred axial load conditions, with respect to one or more of the end caps of the cartridge. Some cartridge configurations provided include no core structure or outer liner structure therein, to support axial load. Assemblies using the cartridge, and methods of assembly and use, are provided. The liquid filter cartridge can be a serviceable cartridge, or it can be retained permanently in a housing.

Abstract: A filter vessel has a housing and a lid which together define an internal chamber for carrying a filter. A gasket is positioned between the lid and the housing. In a locked position, the lid and the housing are in sealed contact with the gasket.

Abstract: A filter cartridge in accordance with the present disclosure has a longitudinal axis and comprises a housing, a filter element, and a collar. The housing has a generally cylindrical sidewall and defines an open first end, an axially opposite second end, and a flange projecting radially away from the axis at the first end. The filter element has a ring of filter media circumscribing the axis and extending between first and second end caps. The first end cap has a generally cylindrical wall extending axially between first and second peripheral rims. The wall defines first and second seal glands adjacent the first and second rims which receive first and second seal members, respectively. A ledge projects radially outwardly from the cylindrical wall. The collar has an annular sidewall having a shoulder projecting from an inner surface. The ledge and the shoulder radially overlap and retain the flange therebetween.

Abstract: A filter assembly, a filter cartridge and method of filter fluid are provided. The filter assembly includes a filter base, a filter housing and a filter cartridge within the housing. The filter cartridge strips water from the dirty fluid flowing through the assembly. The filter cartridge defines a pair of fluid flow paths extending through a central cavity thereof. The fluid flow paths carry and keep separated a flow of cleaned fluid after it passes through filter media of the cartridge as well as the water that has been stripped from the dirty fluid flow.

Abstract: A filter including a container and a basket which is contained in the container and has mounted thereto a bag-like filter element and filtering liquid to be processed by allowing the liquid to pass through the filter element. The filter includes an upper tubular section forming the upper part of the basket and having an upper end open, and an annular seal mounted inside the container and held between the upper tubular section and the container. The upper tubular section has a first fitting surface having an outer diameter decreasing downward. The seal has a second fitting surface having an inner diameter which decreases downward and engaging with the first fitting surface. When the seal receives force acting outward radially from the upper tubular section, compressive deformation of the seal is limited to a predetermined amount.

Abstract: Disclosed in this specification is a method for making a pleated filter cartridge by placing a pleated filter on a mold and adding a polymerizable potting compound to the inner cavity of the pleated filter. The potting compound is permitted to cover the portion of the upper surface of the mold that is encompassed by the pleats. The potting compound is selected to form a polyurethane after polymerization is complete.

Abstract: A filter system has a housing with a housing wall and at least one cover. An inlet is arranged on the housing and feeds a liquid to be filtered into the housing. An outlet is arranged on the housing and discharges the liquid that has been filtered from the housing. At least one filter element is arranged between the inlet and the outlet and separates a raw side of the filter system from a clean side of the filter system. A gasket is arranged between a sealing surface of the housing wall and a sealing surface of the cover. The gasket is held in position in a longitudinal direction of the housing by at least one retaining element that is arranged on the cover or on the housing wall.

Abstract: A filter element having an end cap is provided with a seal that can better accommodate non-round holes. The seal may be a chevron type seal and/or other similar seal having a sealing flange for forming a radial seal. Methods of replacing a filter having an O-ring gasket to improve upon sealing are provided as well as filtration systems employing the filter element.

Abstract: A filtration cartridge of a cartridge-based filtration system is provided that includes annular ring arrangements on one or more end caps and the shell of the filtration cartridge. Once engaged, the annular ring arrangements form a coefficient of friction between the end cap(s) and the shell to create a substantially water-tight seal between the end cap(s) and the shell of the filtration cartridge. Annular locking arrangements may be included in addition to, or in lieu of, the annular ring arrangements to lock the end cap(s) to the shell when the filtration cartridge is utilized in high-pressure applications.

Abstract: A filter device comprises a hollow cylindrical filter element in a filter housing. The fluid that is to be purified is to radially flow through the filter element. The interior of the filter element forms an axial flow chamber for the fluid. An end plate is arranged on the front side of the filter element. An annular neck, onto which a sealing element is injection-molded, is connected to the end plate.

Abstract: A filter within a filter cartridge design is described that includes a sealing structure on an endplate of an outer filter element. Generally, the sealing structure includes an annular flange on the endplate that can directly seal against an interior surface of a housing when the filter cartridge is assembled for use. During filtration, the annular flange prevents a working fluid from bypassing the outer filter element. The sealing flange can seal with the housing in a press fit engagement.

Abstract: A dual bag filter is provided where a replaceable filter element resides in and is sealed to a filter housing. The filter element has a mounting ring, an inner bag, and an outer bag. The inner bag is sized such that it has more surface area than the outer bag and is constrained by the outer bag. The inner bag is formed from a filter medium of different densities such that when the inner bag is crumpled, fluid flow is not restricted.

Abstract: Apparatus for contacting body fluids with the bio-affinity material is disclosed. The apparatus includes a container having top and bottom lock covers that clip onto the container.

Abstract: The invention relates to a filter element, comprising a filter medium (10) having a concentric shape and pleated in a zig-zag shape, a first open or closed end disk (11) arranged on a face and a second end disk (12) arranged on the opposing face. The end disk (12) comprises a concentric opening (13) and extends in a substantially annular shape over the pleats of the filter medium. The end disk (12) further comprises a first ring bead (14) extending axially to the outside and a sealing groove (16). The ring bead (14) comprises outer faces (18, 19), which are supported on radially extending ribs (20, 21) of a housing receiving the filter element or on a flat surface having channels.

Abstract: A filter module includes a filter element with a ring of media and an end cap at one end of the ring. The end cap includes an annular body with a sealing member located around a surface of the body circumscribing a central opening, wherein the sealing member has a repeating, undulating, non-planar geometry. The axial, distal end of the annular body also has an repeating, undulating non-planar geometry, matching the geometry of the sealing member, and can have one or more tabs projecting axially outward from the distal end, positioned at a point of maximum amplitude of the distal end, and which are received in cooperating slots formed in a socket of a diaphragm, to facilitate positioning and installing the element into the module. The socket includes an outer wall having a matching non-planar geometry which receives and seals against the sealing member on the end cap.

Abstract: A membrane separation unit can include a cartridge, at least one membrane disposed within the cartridge, at least one seal plate, and a sealing ring seated in an outer groove of the seal plate. The at least one seal plate can seal one end of the cartridge. The seal plate can have at least one venting hole that forms a passage between the interior of the cartridge and the outer groove. The sealing ring can have a cross-sectional shape that forms a circular venting path between the sealing ring and the seal plate. The sealing ring can include one or more grooves to allow fluid to vent into an annular space between a device housing and the membrane separation unit. The sealing ring can include an outer surface having, in cross-section, two flattened surfaces that form an angle of between 90° and 175° there between.

Abstract: The fluidized bed processor of the present invention includes an internal filter assembly with a rack and a cartridge-type filter supported at the lower end by a bracket. The rack includes an elongated rod extending through the filter. An end cap is provided on the lower end of the rod for normal sealing engagement with the filter bracket. During normal operation of the processor, the upper and lower ends of the filter are sealed. During or after cleaning of the filter, the rack is lowered, and a spring separates the filter and support bracket from the end cap so as to create a gap for drainage of cleaning fluid.

Abstract: A filter assembly includes a disposable filter body and a central support for the disposable filter body. Openings are provided in upper and lower ends of the disposable filter body for receiving a respective end of the central support. The filter assembly also includes a disposable filter cartridge, housed within the disposable filter body, and housing a filter member for filtering particulate contaminates from a flow of fluid through the filter assembly. The filter member is hollow and the disposable filter cartridge also includes an impermeable wall that extends axially through the filter member. The central support is separable from the disposable filter body and removable from the openings to allow disposal and replacement of the filter body and the filter cartridge during servicing.

Abstract: A fluid treatment system for treating feed water includes a first tubular member having first and second ends, at least one second tubular member having first and second ends, a pump positioned within the first tubular member, a filtering membrane positioned within the second tubular member, a first end cap for receiving the first ends of the first and second tubular members, and a second end cap for receiving the second ends of the first and second tubular members.

Abstract: This invention relates to a blood processing filter comprising a sheet-like filter element, an inlet-side flexible container and an outlet-side flexible container that sandwich the filter element and are sealed thereto, an inlet port provided in the inlet-side flexible container for accepting blood before being processed by the filter element, and an outlet port provided in the outlet-side flexible container for discharging blood after being processed by the filter element. The blood processing filter also includes a flow channel securing sheet arranged between the filter element and the outlet-side flexible container. A flow channel hole through which blood processed by the filter element passes is formed in the flow channel securing sheet. The outlet port is provided so as to be capable of communicating with the flow channel hole.

Abstract: The device for filtering water, includes a containment body inside which is placed at least a filter element and includes at least a prefiltration chamber, provided with at least an inlet for the water to be filtered, and at least a postfiltration chamber, provided with at least an outlet for the filtered water, the prefiltration chamber and the postfiltration chamber being in communication with the filter element, where the filter element is substantially sheet shaped and defines an open edge.

Abstract: Z-filter media pack arrangements and methods for providing them are described. The preferred arrangements have a cured-in-place jacket around an outside of a coiled z-filter media combination. The preferred cured-in-place jacket is a mold-in-place overmold which includes, integral therein, a housing seal arrangement. Preferably a cured-in-place center core is used, most preferably one that has opposite concave ends with seal arrangements configured to seal a lead end portion of the coiled z-filter media combination.