Filtering Through Membrane (e.g., Ultrafiltration) Patents (Class 210/650)
  • Patent number: 11266825
    Abstract: A manual clot aspiration and filtration system enables a method of removing a clot without general anesthesia and the expense of an operating room. An aspiration and filtration system for bodily fluid utilizes a syringe coupled with a filter unit to draw bodily fluid through the filter unit to collect debris on the filter. A flow valve may then be turned and the plunger depressed to force the filtered fluid back into the body. The filter may be configured to capture particles such as blood clots and plaque. The filter unit has a cover that can be removed for inspection and/or removal of the collected debris. When the cover is replaced, trapped air may be removed by turning the flow-valve to a purge direction and pressing the plunger into the syringe to force fluid back toward the filter unit to purge the trapped air through the purge valve.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: March 8, 2022
    Assignee: First Pass, LLC
    Inventors: Sunenshine J. Peter, Kevin Hirsch, Joseph Barrett
  • Patent number: 11235288
    Abstract: Embodiments of the present disclosure provide for polystyrene-b-polyethylene oxide (PS-b-PEO) block copolymer nanoporous membranes, methods of making a PS-b-PEO block copolymer nanoporous membrane, methods of using PS-b-PEO block copolymer nanoporous membranes, and the like.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: February 1, 2022
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Klaus-viktor Peinemann, Madhavan Karunakaran
  • Patent number: 11199369
    Abstract: A heat exchanger is provided with a unitary, single-piece structure that can be formed via 3D printing, for example. The heat exchanger includes a main body defining a first fluid inlet port, a first fluid outlet port, a second fluid inlet port, and a second fluid outlet port, wherein each of these fluid ports are integrally formed with the main body. A plurality of plates are stacked and integrally formed with the body. First fluid channels are defined by gaps in the material of the main body and are in fluid communication with the first fluid inlet port. Second fluid channels are defined by gaps in the material of the main body and are in fluid communication with the second fluid inlet port. The first fluid channels and the second fluid channels are interposed between the plates in alternating fashion along the stacked arrangement.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: December 14, 2021
    Assignee: DENSO INTERNATIONAL AMERICA, INC.
    Inventors: John Vandermeer, Sean Schoneboom, Jason Spenny
  • Patent number: 11191879
    Abstract: A cell processing system includes a processor connectable to a source container filled with a biological fluid, the processor including a separator configured to separate the biological fluid from the source container into at least two streams according to a process including at least one process parameter, and a controller coupled to the processor and an input. The controller is configured to receive the at least one process parameter, to evaluate the process using the at least one process parameter before performing the process, and to carry out one or more actions based on the evaluation, such as providing an output estimate to the operator, preventing the process from being performed according to a comparison between a calculated condition and a control, or providing an error indication to the operator according to the calculated condition and a measured in-process condition.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: December 7, 2021
    Assignee: FENWAL, INC.
    Inventors: Christopher J. Wegener, Daniel Boggs, Bret M. Olson, Steven C. Binninger, James D. Hosek
  • Patent number: 11180401
    Abstract: A process for the treatment of wastewater (S1) formed during the production of starches, in particular of chemically modified starches, and which contains dissolved salts and organic compounds, in which process it is proposed that the wastewater (S1) or pretreated wastewater (S1) containing substantially the dissolved salts and the organic compounds of the wastewater (S1) is subjected to a membrane separation process in which a separation of the wastewater (S1) supplied to the membrane separation process into a first volume flow (S3) with a higher concentration of dissolved salts in relation to the supplied wastewater (S1) and a second volume flow (S2) with a reduced concentration of dissolved salts in relation to the supplied wastewater (S1) is performed, wherein the first volume flow (S3) is subjected to thermal treatment for the separation of the dissolved salts and of a third volume flow (S9) which contains a fraction of the organic compounds of the wastewater (S1).
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: November 23, 2021
    Inventor: Franz Gaisch
  • Patent number: 11167251
    Abstract: The present disclosure provides a porous membrane made of pentablock copolymer. The porous membrane includes an ABCBA block copolymer and has a number of pores. The A block is immiscible with each of the B block and the C block, the B block has a glass transition temperature (Tg) of 90 degrees Celsius or greater, and the C block has a Tg of 25 degrees Celsius or less. The A block comprises a poly(alkylene oxide), a substituted epoxide, a polylactam, or a substituted carbonate; B block comprises a vinyl aromatic monomer or a polyalkylmethacrylate and C block comprises a polyacrylate, a polysiloxane or a polyisoprene. A method of making a porous membrane is also provided. The method includes forming a film or a hollow fiber from a solution including a solvent and solids containing an ABCBA block copolymer. The method further includes removing at least a portion of the solvent from the film or the hollow fiber and contacting the film or the hollow fiber with a nonsolvent.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: November 9, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Michelle M. Mok, Carl A. Laskowski, Lucas D. McIntosh, Hyacinth L. Lechuga, Timothy M. Gillard, Clinton P. Waller, Jr.
  • Patent number: 11148098
    Abstract: A spiral wound membrane module including a specialized end cap assembly including a connecting conduit defining a passageway extending radially inward from its outer periphery, and a differential pressure sensor connected to the passageway of the connecting conduit.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: October 19, 2021
    Assignee: DDP SPECIALTY ELECTRONIC MATERIALS US, LLC
    Inventors: Steven D. Jons, Luke Franklin, Ian A. Tomlinson
  • Patent number: 11141699
    Abstract: An immersed hollow fiber membrane module according to an embodiment of the present disclosure includes a hollow fiber membrane bundle formed by fixing a plurality of hollow fiber membranes by a potting agent, and a module supporting unit provided at one side of the hollow fiber membrane bundle to support the hollow fiber membrane bundle, the module supporting unit having an air cleaning time delaying portion configured to delay or intermittently maintain an air cleaning time for air introduced therein and discharged out.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: October 12, 2021
    Assignees: SEOJIN ENERGY CO., LTD.
    Inventors: Tea Hyoung Lim, Seung Kyun Park, Sung Hyo An, Hyun Hoon Jung, Jae Young Lee, Ji Yun Seon, Jun Kim
  • Patent number: 11125729
    Abstract: In various aspects provided are purification media and containers for dispensing a purified liquid are provided herein where a high surface area-to-volume chemically interactive purification media positioned at the outlet of a container that purifies the liquid as it is dispensed and/or extracted.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: September 21, 2021
    Assignee: WATERS TECHNOLOGIES CORPORATION
    Inventors: Moon Chul Jung, Abhijit Tarafder, Wade P. Leveille
  • Patent number: 11123467
    Abstract: The present system and method are useful for the removal of immune inhibitors such as soluble TNF receptors from the body fluid of cancer patients. In some embodiments, soluble TNF-Receptors 1 and 2 are selectively removed from plasma at 80% or more efficiency. In some embodiments, the system includes an immobilized capture ligand of a single chain TNF?. The system and method are useful for the treatment of different cancer types, stages and severity.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: September 21, 2021
    Assignee: IMMUNICOM, INC.
    Inventors: Steven Josephs, Matthew Ong, Amir Jafri, Robert Segal, Stephen Prince
  • Patent number: 11119013
    Abstract: Provided are methods, devices, and kits for the isolation of extracellular vesicles using silicon nanomembranes. A method for EV isolation includes the steps of collecting a biofluid sample, contacting the biofluid sample with a pre-filtration membrane, thereby forming a first filtrate and a first retentate, optionally, washing the first retentate of the pre-filtration membrane, contacting the first filtrate from the pre-filtration membrane with a capture membrane, thereb forming a second filtrate and a second retentate, optionally, washing the second retentate, and eluting the second retentate from the capture membrane or lysing the second retentate to recover the contents.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: September 14, 2021
    Assignee: Simpore Inc.
    Inventors: Jared A. Carter, Akash S. Patel, Cassandra R. Walinski, James A. Roussie
  • Patent number: 11077404
    Abstract: Systems and methods used to control tangential flow filtration are provided, including control systems and methods for use with connected systems with upstream processing units, such as chromatography processing units, in fluid communication with a tangential flow filtration processing unit. Also included are control systems and methods for performing continuous concentration using single-pass tangential flow filtration with permeate flow control.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: August 3, 2021
    Assignee: AMGEN INC.
    Inventors: Eva Gefroh, Randolph W. Schweickart, Krista Petty, Gregory Frank, Christine Salstrom Terpsma, Arthur C. Hewig, III, Joseph Edward Shultz
  • Patent number: 11065583
    Abstract: A process for the preparation of ultrafiltration and microfiltration polymeric flat sheet separation membranes is disclosed, the process comprising a unidirectional cooling step. Membranes prepared according to the process exhibit numerous advantages over ultrafiltration and microfiltration membranes prepared via conventional processes. In particular, the membranes prepared by the present process exhibit remarkable pure water flux, superior mechanical properties and increased anti-fouling characteristics. Also disclosed are particular PVDF ultrafiltration and microfiltration membranes having improved flux, mechanical and anti-fouling properties.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: July 20, 2021
    Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: Bo Wang, Jing Ji, Kang Li
  • Patent number: 11069908
    Abstract: A flow plate for a humidifier, and to such a humidifier having a plurality of flow plates and water exchange membranes are described. The flow plate has a flow field with a plurality of free-standing support elements, wherein the support elements extend, at least in sections, perpendicular to the flat surface plane of the flow plate. Gas to be humidified or gas giving off moisture flows on the flow field. In the humidifier, the flow plates are arranged in a stack, wherein a membrane composite having at least one water exchange membrane is arranged between each pair of adjacent flow plates in the stack. The support elements improve the performance of the humidifier and therefore the number of flow plates can be reduced, making a lower-weight and space-saving design possible.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: July 20, 2021
    Assignee: REINZ-DICHTUNGS-GMBH
    Inventors: Werner Buntz, Rainer Glueck, Andre Speidel, Thomas Stoehr
  • Patent number: 11027240
    Abstract: Disclosed herein methods for combating biofouling in a liquid, e.g. an aqueous medium by providing a surface coated with at least one laser-induced graphene (LIG) layer in said liquid medium. Particularly disclosed herein method and devices for treating water comprising passing a water stream through a membrane module equipped with at least one spacer coated with at least one layer of LIG, and optionally by applying an electric potential to the at least one LIG layer to achieve a bactericidal effect in the water stream. Specifically, disclosed herein a polymeric mesh suitable for use as a spacer in a membrane module in water treatment application, said mesh being at least partially coated with LIG.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: June 8, 2021
    Assignees: B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University, William Marsh Rice University
    Inventors: Christopher John Arnusch, Swatantra Pratap Singh, Franklin Sargunaraj, Yoram Oren, James Mitchell Tour, Yilun Li
  • Patent number: 11000564
    Abstract: A composition comprising extracts containing oil palm phenolics in an amount effective for use in a method of reducing cholesterol biosynthesis and thus preventing obesity. The composition up regulates fatty acid beta oxidation and down regulates cholesterol biosynthesis in livers. The composition is useful for prevention of obesity associated diseases. The composition delays the onset of obesity and attenuates the inflammatory response of atherogenic diet, whereby the composition aids to suppress the inflammatory response thereby ameliorating artherosclerosis. The composition delays weight gain or obesity thereby preventing the effects of dyslipidemia.
    Type: Grant
    Filed: February 17, 2018
    Date of Patent: May 11, 2021
    Assignee: MALAYSIAN PALM OIL BOARD
    Inventors: Soon Sen Leow, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri wahid
  • Patent number: 10987639
    Abstract: Provided is a an amphiphilic diblock copolymer including from 40 to 60% by weight, relative to the weight of the copolymer, of a hydrophilic block including a unit derived from an n-butyl acrylate monomer and a derived from a hydroxyethyl methacrylate monomer. The copolymer also includes from 40 to 60% by weight, relative to the weight of the copolymer, of a hydrophobic block including at least one unit derived from a methyl methacrylate monomer. Also provided is a polymeric membrane that includes the block copolymer and a hydrophobic polymeric matrix. This membrane is useful for treating an effluent, for example, water.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: April 27, 2021
    Assignees: Arkema France, Polymem
    Inventors: Walter Phillip Kosar, Olivier Lorain, Sébastien Marcellino, François Beaume, Pierre Gerard
  • Patent number: 10981119
    Abstract: The invention relates to a gas in/outlet-adapter system for a container/rack assembly for a diagnostic robot comprising: —a receptacle (15) comprising a gas-inlet wherein the receptacle (15) is attached to a container (12), —a nozzle (16) comprising a gas-outlet wherein the nozzle (16) is attached to a rack to supply the container (12) via the receptacle (15) with a gas at a defined pressure level, wherein the receptacle (12) —provides one opening (24) —which provides for a fluidic contact to the interior of the container (12) —and a second opening (25) —which provides for a gas leak-proof connection to the nozzle (16) on the rack when the receptacle (15) is placed over the nozzle (16), and wherein the nozzle (16) —provides one opening (26) —which provides for a fluidic contact to a tubing system of the rack—and a second opening (27) —which provides for a fluidic contact to the nozzle (16) when the receptacle (15) is placed to cover the nozzle (15).
    Type: Grant
    Filed: February 18, 2017
    Date of Patent: April 20, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Claus Tuma
  • Patent number: 10974202
    Abstract: The present invention relates to modified ceramic membranes for the treatment of water. The invention discloses a modified ceramic membrane, comprising: a ceramic membrane, and an outer surface of said ceramic membrane is grafted by a hydrophilic organosilane, wherein said organosilane is selected from the group consisting of: CH30(C2H40)x(CH2)ySi(OCH3)3, where x is >4 and y is >0; CH30(C2H40)x(CH2)ySi(OCH2CH3)3, where x is >4 and y is >0; (CH30)3Si(CH2)yO(C2H40)x(CH2)ySi(OCH3)3, N where x is >4 and y is >0; and (CH3CH20)3Si(CH2)yO(C2H40)x(CH2)ySi(OCH2CI-13)3, where x is >4 and y is >0.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: April 13, 2021
    Assignee: HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATURAL RESOURCES
    Inventors: Saviz Mortazavi, Andre Yves Tremblay, Charbel Atallah
  • Patent number: 10920559
    Abstract: An inverted Y-tool is positioned in multiphase wellbore fluid flowing through a wellbore. The inverted Y-tool separates at least a portion of gas from the multiphase wellbore fluid and, after separating at least the portion of the gas from the multiphase wellbore fluid, directs the multiphase wellbore fluid to a downhole pump that pumps the wellbore fluid in an uphole direction.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: February 16, 2021
    Assignee: Saudi Arabian Oil Company
    Inventor: Amr Mohamed Zahran
  • Patent number: 10906011
    Abstract: The present invention relates to a layered semipermeable membrane satisfying the conditions below. (A) The maximum peak intensity between 3700 and 2900 cm?1 is 0.08 or greater in the difference spectrum between an IR spectrum measured at 25° C. and 97% relative humidity and an IR spectrum measured at 25° C. and 3% relative humidity. (B) The peak top wavenumber between 3700 and 2900 cm?1 of the aforementioned difference spectrum is 3400 cm?1 to 3550 cm?1. (C) The N1s peak has a maximum value at 401 eV or greater in X-ray photoelectron spectroscopy in which X-rays are radiated to a coat layer.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: February 2, 2021
    Assignee: TORAY INDUSTRIES, INC.
    Inventors: Takahiro Tokuyama, Takafumi Ogawa, Hiroki Tomioka
  • Patent number: 10889915
    Abstract: Systems and methods can be used to produce fibers with external corrugations, internal corrugations, or both. These fibers can be used, for example, in hollow fiber membrane modules.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: January 12, 2021
    Assignee: Saudi Arabian Oil Company
    Inventors: Seung-Hak Choi, Sarah N. Almahfoodh
  • Patent number: 10876963
    Abstract: The present invention relates to devices and methods for improving and evaluating stability of pumped protein solutions in cross-flow filtration applications. Inter alia, the present invention provides a peristaltic pump for cross-flow filtration having a pump head, wherein the pump head comprises a stepped occlusion plate and at least one pump roller, wherein a tubing is to be arranged between the stepped occlusion plate and the at least one pump roller, wherein the stepped occlusion plate has a specific configuration.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: December 29, 2020
    Inventors: Adrian Neil Bargh, John Paul James Betts
  • Patent number: 10865112
    Abstract: Modified substrates are provided having nano- or microscale wells, tracks, channels, pores or perforations. Also provided are methods of making the same.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: December 15, 2020
    Assignee: Lockheed Martin Corporation
    Inventors: Scott E. Heise, Han Liu, Jacob L. Swett, Michael J. Hiltabidle
  • Patent number: 10821404
    Abstract: A control method is provided for a filter system, which includes at least one filter element (2). The method includes continuously recording a total energy consumption (EG) during a filtration cycle (22) of the filter system. The total energy consumption (EG) includes at least of the energy consumption (EB) for a physical cleaning (24) and the energy consumption (EP) for the subsequent production cycle (23) up to a predefined, in particular current point in time. The method further includes computing a relative energy consumption (Erel) by way of division of the recorded total energy consumption (EG) by a net permeate volume (QN) which has been produced during the filtration cycle (22) up to the predefined point in time and starting a physical cleaning (24) in dependence on the relative energy consumption or of a characteristic value derived from this.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: November 3, 2020
    Assignee: GRUNDFOS HOLDING A/S
    Inventors: Dominik Dominiak, Jacob Appelt Vibe Svendsen, Christian Rasmussen, Rune Hoejsholt
  • Patent number: 10822635
    Abstract: Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: November 3, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Ozan Akkus, Mikhail Slipchenko, Anna Akkus, Shan Yang, Bolan Li
  • Patent number: 10814287
    Abstract: The present disclosure provides a multilayer article. The multilayer article includes a) a microfiltration membrane substrate; b) a first layer directly attached to the first major surface of the microfiltration membrane substrate; and c) a second layer directly attached to the first layer. The first layer includes a first polymeric binder and acid-sintered interconnected first silica nanoparticles arranged to form a continuous three-dimensional porous network. The second layer includes acid-sintered interconnected second silica nanoparticles arranged to form a continuous three-dimensional porous network. The present disclosure also provides a method for forming a multilayer article.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: October 27, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Chunjie Zhang, Hongying Jiang, Xuan Jiang, Naiyong Jing
  • Patent number: 10807890
    Abstract: The invention provides a water purification system or a water treatment system comprising carbon nanotubes, as well as methods for purifying or treating water using the systems of the invention.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: October 20, 2020
    Assignee: University of Iowa Research Foundation
    Inventors: David M. Cwiertny, Jason P. Haase
  • Patent number: 10800666
    Abstract: A filtration system has a filter unit and a holder module. The filter unit has an inlet side and an outlet side being opposite each other, and has at least one filter module. The holder module has at least one holder element and two tightening assemblies. The at least one holder element fixes the at least one filter module, and the tightening assemblies are respectively mounted at the inlet side and the outlet side of the filter unit. The quantities of the filter modules of the filter unit may be increased or decreased.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: October 13, 2020
    Assignee: PLAINLIV TAIWAN CO., LTD.
    Inventors: Kai-Chih Hsing, Wen-Yi Huang
  • Patent number: 10766800
    Abstract: The present invention relates to a process for the selective removal of nitrates from ground water using a hybrid nanofiltration (NF)—reverse osmosis (RO) filtration system. The process generates product water that is low in nitrate and can be used for drinking, irrigation and other purposes, as well as waste water that is relatively low in salinity and can be safely discarded to sewage systems and recycled, e.g., for irrigation purposes.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: September 8, 2020
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Michal Green, Ori Lahav, Razi Epsztein, Oded Nir
  • Patent number: 10737006
    Abstract: A flow rate of blood through an implantable blood pump is determined based on a parameter related to the flow, such as a parameter related to thrust on the rotor of the pump. An amount of current supplied to the pump is used to determine each of a first flow rate value and second flow rate values. Each of the first and second flow rate values, in combination with the parameter related to thrust on the rotor of the pump, are used to calculate a flow rate of blood through the pump.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: August 11, 2020
    Assignee: HeartWare, Inc.
    Inventors: Fernando Casas, Justin Wolman, Carlos Reyes, Antonio Luiz Silva Ferreira
  • Patent number: 10736847
    Abstract: Methods and devices for producing a population of liposomes are provided. Aspects of the methods include applying a centrifugal force to a suspension of liposomes in a manner sufficient to pass the liposomes through a porous membrane to produce a population of liposomes. Aspects of the invention further include devices, systems and kits useful for performing the methods.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: August 11, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Oleg Guryev, Aaron J. Middlebrook, Marybeth Sharkey
  • Patent number: 10734667
    Abstract: A negative electrode electrolyte solution which contains titanium ions, a chelating agent, and a catechol-based compound having a catechol structure is used for a negative electrode of a flow battery in which an electrolyte solution is circulated so as to perform charge and discharge.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: August 4, 2020
    Assignee: KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO
    Inventor: Jiro Sakata
  • Patent number: 10730017
    Abstract: The disclosed technology relates to a water filtration and delivery system for a dialysis unit. The water nitration and delivery system including: a laminarizer, the laminizer producing a laminarizer flow; an ultrafiltration unit, the ultrafiltration unit being placed downstream and connected to the laminarizer, the ultrafiltration unit receiving the laminar flow from the laminarizer; and at least one carbon filter, the at least one carbon filter being placed downstream from the ultrafiltration unit, the at least one carbon filter receiving the laminar flow, wherein the laminar flow causes less stress on internal components of the ultrafiltration unit and the at least one carbon filter.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: August 4, 2020
    Inventor: Manuel S. Avakian
  • Patent number: 10729663
    Abstract: The present invention provides a sustained drug delivery system for the treatment of age-related macular degeneration (AMD), comprising corticosteroid encapsulated nanoparticles incorporated into a thermoreversible hydrogel. The corticosteroid may be triamcinolone acetate (TA), dexamethasone, or loteprednol etabonate (LE). The proposed drug delivery system is nontoxic to ARPE-19 (retinal pigment epithelium) cells and significantly reduces VEGF (vascular endothelial growth factor) expression as compared to solutions of the coticosteroids. The present invention provides sustained delivery of the corticosteroid to the posterior segment of the eye, reducing the frequency of intraocular injections necessary to maintain therapeutic concentrations.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: August 4, 2020
    Assignee: University of South Florida
    Inventors: Vijaykumar Bhadabhai Sutariya, Anjali A. Hirani, Yashwant V. Pathak
  • Patent number: 10717027
    Abstract: The present invention is a modified apparatus for wastewater recycling including a toilet tank device, a water amount control assembly, and a three-way pipe. The toilet tank device includes a filtering space provided with a filtering apparatus and a water level sensing apparatus and a device area provided with a pressurizing device, at least one filter, and a transfer pipe. The water amount control assembly includes a driving apparatus, a cleaning pipe group, and a wastewater transfer pipe group. When clean water is transferred to clean the filter, the clean water can be transferred through a combination of the cleaning pipe group and the pressurizing device with a water amount controlled by the driving apparatus, and wastewater passing through the filtering apparatus can be transferred through a combination of the wastewater transfer pipe group and the pressurizing device with a water output amount controlled by the driving apparatus.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: July 21, 2020
    Inventor: Zhen-Fa Guan
  • Patent number: 10675556
    Abstract: Liquid purification methods and apparatus are disclosed. An example apparatus includes a frame to define an interior space, the frame having an inner surface in contact with air of the interior space; a barrier positioned between a body of liquid and the interior space; and an absorber suspended from the frame to transfer liquid from the body of liquid into the interior space via an opening in the barrier.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: June 9, 2020
    Assignees: AT&T INTELLECTUAL PROPERTY I, L.P., AT&T MOBILITY II, LLC
    Inventors: Sheldon Kent Meredith, William C. Cottrill, Jeremy T. Fix
  • Patent number: 10668417
    Abstract: The invention relates to a device for extracting nucleic acid from a formalin-fixed and paraffin-embedded sample comprising a hollow body having an inlet port and an outlet port and a filter layer arranged within the hollow body, wherein the device is characterized in that the filter layer has an oil repellency of at least grade 5 according to the test method by AATCC-118 (1997). The invention further relates to a method for extracting nucleic acids from a formalin-fixed and paraffin-embedded sample, and a kit comprising the inventive device.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: June 2, 2020
    Assignee: AXAGARIUS GMBH & CO. KG
    Inventors: Florian Werner, Stefan Heymans, Thomas Zinn
  • Patent number: 10662084
    Abstract: The present disclosure provides systems for data center cooling and water desalination. In some aspects, the systems include a data center having a water cooling subsystem configured to receive cool water and output warm water and a desalination plant co-located with the data center and configured to receive and desalinate the warm water. Aspects of the invention also include methods for cooling a data center using a water cooling subsystem and desalinating water with a desalination plant that is co-located with the data center.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: May 26, 2020
    Assignee: DeepWater Desal LLC
    Inventor: Brent Richard Constantz
  • Patent number: 10603420
    Abstract: A blood treatment device includes a heat exchanger having a first space and a second space, with a first fluid flowing through the first space and a second fluid flowing through the second space. The heat exchanger has a membrane which separates the first space from the second space, with the membrane forming a component of a capacitor having two capacitor plates, between which the membrane is located. A monitoring means is connected to the capacitor, and is configured to detect an electrical property of the capacitor, for the purpose of detecting a fluid leak from the first space to the second space.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: March 31, 2020
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Reiner Spickermann, Klaus Balschat, Tilman Staeblein, Arne Peters, Peter Kloeffel
  • Patent number: 10596524
    Abstract: The present invention relates to a hollow fiber membrane. Provided is a cylindrical hollow fiber membrane having an inside in which a hollow part is formed along an axial direction, the hollow fiber membrane including: a first layer positioned at the outermost part so as to be exposed to the outside, and having pores formed therein to make raw water enter and leave via the pores; a second layer formed on the inside of the first layer to filter out contaminants from raw water as the raw water passes through; and a third layer to optionally separate or filter out contaminants from the raw water introduced through the second layer or introduced from the hollow part, wherein the first layer to the third layer are integrally formed; the porosity of the first layer is greater than the porosity of the third layer; and porosities are gradually decreased from the first layer to the third layer.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: March 24, 2020
    Assignee: LG CHEM, LTD.
    Inventors: Jooyoung Park, Jongdeok Kim, Junseok Lee
  • Patent number: 10532323
    Abstract: The group of inventions relates to technologies for purifying liquid, primarily water for the domestic and/or drinking water supply in domestic and/or industrial conditions and in allotments and gardens. The characterizing feature of the group of inventions is that the design of a hollow fibre membrane device envisages, and a method for the manufacture thereof enables, the formation of a protective layer consisting of a single polymeric fixing material on the internal surfaces of mono-fibre sections which are incorporated into a binding unit, and the formation of sections which are in the form of a composite in the binding unit, which increases the strength of the hollow fibre membrane device, wherein open channels in the binding unit, formed with the aid of protective elements of an assembly base, make it possible to increase the specific filtering surface.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: January 14, 2020
    Assignee: Electrophor Inc.
    Inventors: Joseph Lvovich Shmidt, Nikolaj Victorovich Erukov, Stanislav Sergeevich Kuznetsov
  • Patent number: 10471391
    Abstract: Embodiments of the present invention provide for flow control devices on a spiral wound membrane, on a device proximal the inlet edge of a spiral wound membrane, or both. The flow directing devices can alter fluid flow characteristics to discourage fouling of the inlet fluid paths.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: November 12, 2019
    Assignee: Aqua Membranes, Inc.
    Inventors: Kevin Roderick, Rodney Herrington
  • Patent number: 10457904
    Abstract: A system, method, and apparatus for the fermentation of a beverage by use of continuous flow is provided. The fermented beverage can be any of a wine, beer, mead, ale, soda, cider, or other. The invention provides for small-scale fermentation that can be done in a much shorter time than previous batch fermentations. The small-scale and shortened time allows for variables to be introduced and tested to produce new varieties, flavors, qualities, and other combinations that are inputs of the fermented beverage.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: October 29, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Daniel Attinger, Liang Dong, Yuncong Chen
  • Patent number: 10434476
    Abstract: The invention relates to a multilayer metallic or ceramic membrane device, comprising a macroporous carrier layer including pores having a pore diameter of more than 50 nm, and at least one mesoporous intermediate layer disposed thereon, including pores having a pore diameter of 2 nm to 50 nm. The membrane device according to the invention furthermore comprises at least one microporous cover layer disposed on the mesoporous intermediate layer, including pores having an average pore diameter of 0.3 nm to 1.5 nm, comprising graphite oxide or few-layer graphene oxide or graphite or few-layer graphene. In an advantageous embodiment, the cover layer comprises between 5 and 1000 layers of graphene oxide. In an advantageous embodiment, the cover layer can comprise between 5 and 1000 layers of partially reduced graphene oxide or graphene as a result of the at least partial reduction of the graphene oxide.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: October 8, 2019
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Tim Van Gestel, Oliver Guillon
  • Patent number: 10428357
    Abstract: The subject invention relates to a process of preparing (R)-3-hydroxybutyric acid or a salt thereof by one-step fermentation with a nonpathogenic microorganism. The fermentation of (R)-3-hydroxybutyric acid was performed by supplying with certain carbon and nitrogen sources. These microorganisms include a Glutamic acid Bacterium HR057 strain or one type of genetically engineered Corynebacterium Glutamicum.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: October 1, 2019
    Assignee: NNB Nutrition USA, LLC
    Inventors: Kylin Liao, Wenchao Fan
  • Patent number: 10426158
    Abstract: The invention concerns methods of treating stored blood and blood products maximizing shelf life and/or minimizing transfusion related complications such as non¬ hemolytic transfusion reactions such as fever, transfusion-related acute lung injury (TRALI), transfusion associated dyspnea (TAD), and allergic reactions by removing undesirable molecules in the blood and blood products milieu through use of a sorbent.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: October 1, 2019
    Assignee: CytoSorbents Corporation
    Inventors: Phillip P. Chan, Vincent J. Capponi, Thomas D. Golobish, Humayra Begum Ali
  • Patent number: 10392270
    Abstract: A multi-effect membrane distillation system includes first and second membrane distillation effects. Each effect (stage) includes a feed channel, a gap, and a vapor-permeable membrane separating the feed channel from the gap. A liquid feed is fed into the feed channel of the first effect via a feed inlet, and the liquid feed is extracted from the first-stage feed channel via a first feed-transfer conduit that delivers the liquid feed to the second-stage feed channel. The feed is extracted from the second-stage feed channel via a second feed-transfer conduit. At least one permeate-extraction conduit is coupled with the first-stage and second-stage gaps and is configured to extract permeate (e.g., pure water) therefrom.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: August 27, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Jaichander Swaminathan, Ronan K. McGovern, Hyung-Won Chung, David Elan-Martin Warsinger, John H. Lienhard
  • Patent number: 10369263
    Abstract: In embodiments of the invention, there is provided a dialyzer or filter comprising hollow fibers, in which blood flows on the exterior of the hollow fibers, and dialysate or filtrate may flow on the inside. The external surfaces of the hollow fibers may have properties of smoothness and hemocompatibility. The fiber bundle may have appropriate packing fraction and may have wavy fibers. Optimum shear rates and blood velocities are identified. Geometric features of the cartridge, such as pertaining to flow distribution of the blood, may be different for different ends of the cartridge. Air bleed and emboli traps may be provided. Lengthened service life may be achieved by combinations of these features, which may permit additional therapies and applications or better economics.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: August 6, 2019
    Assignee: Novaflux Inc.
    Inventors: Mohamed E. Labib, Stanislav S. Dukhin
  • Patent number: 10369262
    Abstract: A blood processing apparatus includes an optional heat exchanger and a gas exchanger disposed within a housing. In some instances, the gas exchanger can include a screen filter spirally wound into the gas exchanger such that blood passing through the gas exchanger passes through the screen filter and is filtered by the spirally wound screen filter a plurality of times.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: August 6, 2019
    Assignee: Sorin Group Italia S.r.l.
    Inventor: Stefano Reggiani