Abstract: A manufacturing method includes an injection molding process of injection-molding a preform, a temperature adjustment process of temperature-adjusting the preform while cooling the preform, and a blow molding process of blow-molding the temperature-adjusted preform to manufacture a resin container. In the injection molding process, a step portion thicker than at least an engagement groove of a neck portion is formed between the neck portion and a body portion of the preform.

Abstract: The present disclosure relates to storage-stable proton pump inhibitor (PPI) systems comprising a therapeutically effective amount of a PPI or a pharmaceutically acceptable salt thereof, such as omeprazole or a pharmaceutically acceptable salt thereof, which are constituted with water prior to administration. The present disclosure also relates to oral pharmaceutical suspensions comprising water, a therapeutically effective amount of a PPI or a pharmaceutically acceptable salt thereof, such as omeprazole or a pharmaceutically acceptable salt thereof, and one or more buffering agents.

Abstract: A cap assembly for a container, including a base defining a base plane, a drink spout separate from the base and extending away from the base, a closure configured to selectively transition between a closed configuration, in which the closure is engaged with the drink spout and obstructs a passage through the drink spout, and an open configuration, in which the closure is not engaged with the drink spout and does not obstruct the passage through the drink spout, and a closure retention mechanism configured to retain the closure in any one of a plurality of stowed positions against the base.

Abstract: A unitary, single-use, sanitary sterilizing wipe for a beverage can. It has a number of can wiping interfaces incorporated into its design that matingly conforms to a standard beverage can, and uses a natural sterilizing fluid that is frictionally wiped onto the can's outer surfaces before drinking from the can. It may be used anywhere by opening the polymer seal, removing the wipe, placing it on the top of a beverage can and twisting it under pressure to sterilize the can.

Abstract: The tumbler bottle includes a cup having a side wall interior surface and bottom wall a convex interior surface. The cup side wall and bottom wall interior surfaces are joined by a smooth, arcuate interior transition surface to define a first mixing chamber. The tumbler bottle further includes a lid, removably connected with the cup. The lid includes a side wall interior surface and a top wall concave interior surface. The lid side wall and top wall interior surfaces are joined by a smooth, arcuate interior transition surface to define a second mixing chamber. The lid further includes a dispensing outlet and a closure. When coupled together the first mixing chamber and the second mixing chamber are in fluid communication and are configured to uniformly mix a liquid with one or more additives.

Abstract: The present disclosure relates to a bottle with a detachable housing and corresponding storage compartment. Indeed, the disclosed bottle can include a receptacle formed within an exterior side surface (or sidewall) or as part of the bottle lid. Within the receptacle, the disclosed bottle can integrate a detachable housing with the bottle via one or more attachment mechanisms (e.g., magnets). For instance, the disclosed bottle attaches the detachable housing to a receptacle sidewall such that the disclosed bottle can maintain a generally uniform profile across the exterior side surface. The detachable housing can include a storage compartment for storing and/or securing one or more items, such as cutlery, medicine, personal hygiene items, etc.

Abstract: A multi-container dispenser for storing hygiene product, is disclosed. The dispenser comprises a plurality of storage reservoirs and an elongate receptacle body. The storage reservoir is configured to store fluids such as shampoo, and the elongate receptacle body is configured to store hygiene product such as tooth brush. Further, the storage reservoir comprises a dispensing outlet. A resealable cap disposed over each storage reservoir, such that each cap is selectively unsealed and resealed by a user. The dispenser comprises a dispensing arrangement in fluid communication with the plurality of storage reservoir, which is configured for actuation by the user, thereby causes dispensing of fluid from the selected storage reservoir. The storage reservoir being selected by the user by unsealing the selected respective sealable cap.

Abstract: A method for decontaminating a tube of which a first open end forms an inner neck towards the inside of the tube and an outer neck towards the outside of the tube, the method including: initially raising the temperature of the tube, then subjecting the tube to ultraviolet radiation, that includes emitting ultraviolet radiation by radiation emission apparatus, and subjecting the inside of the tube, the outer neck and the inner neck to the ultraviolet radiation, in which the first end is inserted into a cavity arranged to reflect the ultraviolet radiation emitted by the emission apparatus and to direct this ultraviolet radiation into the tube through the first end, onto the outer neck of the tube and onto the inner neck of the tube.

Abstract: This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced.

Abstract: A liquid dispensing apparatus may include a first container containing a first liquid and a second container containing a second liquid. The first and second containers each can have an opening in an end. One of the first liquid and the second liquid can contain a tastant which is essentially absent from the other liquid or is present in a relatively differing amount. When the first and the second liquids are poured from the apparatus, the first liquid flows through the opening in the end of the first container and the second liquid flows through the opening in the end of the second container, such that the first liquid begins to exit the opening in the end of the first container before the second liquid begins to exit the opening in the end of the second container.

Abstract: The claimed invention relates to bottles used by exercise enthusiasts for carrying liquids, solids and/or powdered nutritional supplements with liquids for mixing said supplements. Exercise aficionados consume a variety of hydrating liquids, nutritional supplements mixed with liquids or solid food items before, during and after their exercise periods. People who exercise use a variety of bottles including shakers, squeeze and water bottles to hold and consume their liquids, foods and supplements during their workouts. The present invention is an improved dual compartment shaker bottle for various nutritional supplements, liquids and combinations thereof. The dual compartments allow the user to carry two different liquids, nutritional supplements, combinations of liquids and supplements or solids for use before, during and after their workout. They no longer need two or more shaker bottles to accomplish this.

Abstract: A dental apparatus container, including a main body to receive at least one of a dental apparatus and cleaning fluid therein, and a lid connected to the main body to cover at least a portion of the main body.

Abstract: A culture container includes: a culture container body; a partition plate disposed in the vicinity of a bottom of the culture container body to face the bottom so that a culture region is formed as a culture region between the partition plate and the bottom; and a sample inlet/outlet provided in the culture container body, the culture region and the sample inlet/outlet communicating with each other via an opening formed adjacent to one end of the partition plate. With the culture container and a culture method using this container, a large amount of adipocytes can be cultured at one time with easy handling. Dedifferentiation of a large amount of adipocytes and removal of cells having failed to dedifferentiate can be efficiently accomplished.

Abstract: A drinking bottle includes a first bottle part (10) having an interior (100) for receiving a beverage (G) and a second bottle part (11) having an interior (110) for receiving the beverage (G) and having a bottle opening (13) for dispensing the beverage (G) from the interior (110), wherein the interiors (100, 110) of the two bottle parts (10, 11) are or can be brought into fluid communication with each other. The drinking bottle (1A-1D) has at least one configuration in which the two bottle parts (10, 11) are inclined to each other. The invention also relates to a valve for a drinking bottle. In this way, a drinking bottle can be provided which allows a user to drink in a particularly comfortable position.

Abstract: A method and system to provide a pill bottle with a removable pill cap case. A bottle cap has a hollow area which receives the removable pill cap case which fits (snaps) into the bottle cap. The removable pill cap case has a flip-top lid which can open and close and enable pills to be placed therein. As such, a user can open the pill bottle, place one or more of the pills inside the removable pill cap case, close the removable pill cap case, and then carry the removable pill cap case around with him/her without having the carry the entire pill bottle.

Abstract: A waste container that is configured to be expandable and collapsible so as to provide at least two alternate interior volume capacities. The waste container includes a body having a base member wherein the base member is configured with opposing wheels and a recess for an axle. The body further includes two first ring members and a second ring member wherein the second ring member is intermediate the two first ring members. The second ring member has a diameter that is slightly larger than the first ring members. The two first ring members and a second ring member are configured to be slidably and frictionally engaged so as to provide a first and second position of the waste container. The body further includes a top assembly that is operably coupled to the first ring member above the second ring member. A lid is releasably secure to the top assembly.

Abstract: A system for storing breast milk includes a container having a top opening and a bottom recess extending into an interior of the container towards the top opening. A container cap is configured to attach to the container and cover the top opening. The container cap includes a probe thermometer having a sensing tip positioned above the bottom recess when the container cap is attached to the container. A non-insulated cooling base has a protrusion configured to mate within the recess when the container is resting on the base. An insulated shell assembly includes a top and bottom configured to connect to each other, wherein the shell assembly is configured to at least partially encapsulate the container, the container cap and the cooling base.

Abstract: An apparatus to conceal the contents of a container, having first and second containers. The first container has an internal cavity accessible through a first container opening and is configured to hold a first liquid, the first container having a first container coupling element. The second container has an internal cavity, the second container internal cavity configured to hold a second liquid through a second container opening, wherein at least a portion of the second container is receivable through the first container opening into the first container internal cavity in the first container. The second container has a second container coupling element. The first container coupling element of the first container is engageable with the second container coupling element of the second container to selectively couple the second container to the first container. Coupling the second container to the first container conceals the first container opening.

Abstract: An applicator system comprises a container and an applicator. The container is configured to contain a substance to be applied using the applicator. The container is further configured to support the applicator in an accessible orientation in use. For example, the container can comprise a first chamber that is open at an end thereof. The first chamber can be arranged to receive and locate at least an active end of the applicator therein and to hold the applicator in the accessible orientation in use. The container can also comprise a second chamber that is arranged to receive and hold therein the substance to be contacted by the active end of the applicator in use.

Abstract: A double jigger comprises two cup portions. Each cup portion faces in an opposite direction from one another and each has an open top for receiving a liquid or a pourable solid and a bottom which leads to a common open channel. A pliable center portion is disposed between and connects the two cup portions and contains the common open channel. The channel is subject to blockage upon application of exterior pressure on the pliable center portion, for example, if a user were to pinch the center portion between a thumb and fingers.

Abstract: A drinking vessel with a hidden utensil compartment includes a cup with a recessed side extending from the bottom to a transition below the top. An elongated hollow structure defines a compartment and extends from the bottom against the recessed side. A base secured to the bottom of the cup includes an opening leading to the compartment. A sleeve-like cover contains the cup and the elongated hollow structure. A drawer holding utensils fits through the opening in the base into the compartment. A drawer stop attached to the recessed side includes a spring to facilitate removal of the drawer.

Abstract: A single serve beverage cup, including for a cocktail, is disclosed having a base, a bowl, a seal, a top cover and a bottom cover. The single-serve beverage cup includes a cavity for receiving a miniature liquor bottle for making a cocktail. There are disclosed various embodiments of the bottom cover.

Abstract: A closure capsule for closing a container, comprising: —a cap (2) to be associated with a container and comprising a frangible mouth (20); —a cutter (3) comprising a cutting edge (30) designed to open said frangible mouth (20); at least the cap (2) and the cutter (3) in combination defining a reservoir (8) for containing a substance to be dropped into the container when the frangible mouth (20) is opened; —a protective covering (4) for the cap (2) and the cutter (3), separate from the cutter (3) and, in turn, comprising: i) a lateral wall (40) that encloses a zone (402) for at least partially housing the cutter (3); ii) a base (41) from which said lateral wall (40) extends; —transmitting means (5) for transmitting an opening torque, from the covering to the cutter, for opening the frangible mouth (20), said transmitting means (5) comprising a first and a second portion (51, 52) incorporated in the covering (4) and in the cutter (3), respectively; said first portion (51) being incorporated in the base (41).

Abstract: A container can include a container body, a container top, a closure, and a closure seal. The container top can be connected to the container body. The container top includes a first opening and a second opening. The closure is selectively connected to the container top to control access to the first opening and the second opening. The closure seal is positioned between the closure and the container top. The closure seal comprises a first sealing surface and a second sealing surface. The first sealing surface is sized and configured to at least partially seal the first opening when the closure is connected to the container top. The second sealing surface is sized and configured to at least partially seal the second opening when the closure is connected to the container top.

Abstract: A replaceable jar package includes a push-to-release button, an inner jar sized to fit within the outer jar, the outer jar having a threaded opening at its top and having an opening at its bottom, and having a pair stubs for holding the push-to-release button within the opening at the bottom of the outer jar. The outer jar cooperates with the inner jar to form a snap feature. The inner jar is secured to the outer jar when the snap feature is engaged. The inner jar can be removed from the outer jar when the snap feature becomes disengaged. The snap feature is disengaged by the push-to-release button moving in a direction from the bottom of the outer jar toward a top of the outer jar such that the push-to-release button moves the inner jar relative to the outer jar.

Abstract: An arrangement for the rapid preparation of various products that can be encapsulated includes: a capsule (10) which contains a concentrated dose or an exact measurement of a given product to be diluted (a) and a container (20) for receiving an amount of a given dilution product (b). The capsule (10) is a disposable element having an outlet (11) provided with detachable closure elements (12). The container (20) having a lower opening (21) with a reciprocal connection device (22) capable of forming a firm airtight bond with the opening (11) of the capsule (10) and an top opening (23) adapted for receiving the dilution product (b) and dispensing the mixture (c) including the metered dose (a) of the dilution product (b).

Abstract: Various embodiments of the present disclosure provide a cartridge for dispensing two-part fluids. In one embodiment, the cartridge comprises a cartridge body having a dispensing end and defining a first fluid reservoir and a second fluid reservoir. The dispensing end defines at least one aperture fluidly connected to the first fluid reservoir. The dispensing end also defines a dispensing conduit fluidly connected to the second fluid reservoir. The cartridge further comprises a nozzle member engageable with the cartridge body to form an outlet and to fluidly connect the at least one aperture to the outlet.

Abstract: Drinking receptacles and methods related thereto are described. The drinking receptacles include: a first component comprising a first fluid chamber and a hub assembly engaged thereto; and a second component comprising a fluid-flow regulator attached to a cylindrical body, with a second fluid chamber defined therein, such that pins on an outer surface of the first fluid chamber of the first component slidably engage with channels on an inner surface of the fluid-flow regulator of the second component to form a drinking receptacle, and the drinking receptacle may be transformed, by slidably displacing the first component relative to the second component, between a closed configuration, where a flow path is blocked between the first fluid chamber and the second fluid chamber, and an open configuration, where a flow path is open between the first fluid chamber and the second fluid chamber.

Abstract: A sports bottle is described. The bottle includes a hollow body comprising a housing having a peripheral wall, a cylindrical drink holding chamber inside the peripheral wall; a plurality of mixing chamber in fluid communication with the drink holding chamber, each one of the mixing chambers being hemispherical chambers at opposed ends of the cylindrical drink holding chamber; and an outlet for dispensing drink from the drink holding chamber, the outlet being disposed on an outside of one of the mixing chambers and in fluid communication therewith.

Abstract: A split bottle assembly including a body, a seal, a lower collar, and an upper collar. The body is longitudinally split between a first body portion and a second body portion. The seal is between the first and second body portions. The lower collar and the upper collar are removably fastened to a lower end and an upper end of the body, respectively, thereby biasing the first and second body portions towards one another so that the seal forms a continuous fluid-tight seam therebetween.

Abstract: A separable container and related method for delivering predetermined portions of product contained within a container is provided. The container has a sidewall having a plurality of frangible sections disposed at predetermined distances along the height of the sidewall. A plurality of flexible dividers are interspersed with the product in the container, each of the flexible dividers being substantially aligned with a respective frangible section of the sidewall. Sidewall segments are separable from the container to expose a predetermined portion of the product contained therein, and the flexible dividers define a boundary between adjacent predetermined portions of product to facilitate separation of the exposed predetermined product portions from a remainder of product seated within the container sidewall.

Abstract: Multi-compartment containers including multi-compartment cans, canisters, boxes and bags and methods for using the same are disclosed. Multi-compartment containers that provide access to one portion of the contents until depleted while maintaining a seal and thus protecting the freshness or potency, of the contents on another portion allows products to be packaged and sold in a way that maintains freshness and potency longer. Each compartment of the multi-compartment containers can be configured to have either a single-use or re-sealable seal.

Abstract: A steaming pitcher comprising a flow receiving surface adapted to receive an incoming flow of steam at a substantially oblique angle provides enhanced control of fluid flow inside the steaming pitcher to enhance mixing and heating of the fluid by the incoming steam. The steaming pitcher may also comprise flow directing and launching surfaces to assist in control of fluid flow patterns. A flow control kit with a flow receiving surface may be installed in an existing flat-bottom steaming pitcher to provide aspects of fluid flow control. The flow receiving, flow directing and launching surfaces of the steaming pitcher may be substantially smooth, faceted, or a combination thereof.

Abstract: A container assembly including a primary container and a secondary container removably attached to the primary container. The primary container includes a top, a bottom and a side. The side includes a recess in which the secondary container is located when attached to the primary container. The recess is defined by two side walls extending laterally from a rear wall of the recess toward an outer surface of the side wall. The secondary container includes a top, a bottom and a side. The secondary container is attached to the primary container through a set of securing attachments, each including a protrusion and mating indentation. At least one of the walls of the primary container and the side of the secondary container includes the set of protrusions, and the other of the walls of the primary container and the side of the secondary container includes the set of mating indentations.

Abstract: The present invention is a heat-resistant receptacle cap comprising: an inner cap 100 having an insertion pipe 120 configured to be fitted onto an inlet of a receptacle with a locking hook, a discharge gate 140 connected to the insertion pipe 120 with a small-diameter pipe 145 and formed so that contents in the receptacle is discharged at the small-diameter pipe 145, and a container 200 which is installed at the bottom of the small-diameter pipe 145 and has an open upper part to hold additives therein; a heat-resistant sealing plate 220 configured to heat-seal the insertion pipe 120 and upper wall of the container 200; a sealing plate holder 300 which is provided with a fitting ring 310 that fits the sealing plate 220 to a corresponding part for coupling the heat-resistant sealing plate 220, and which is fitted at an upper end of an inner side wall of an outer cap 400; and the outer cap 400 having a sealing plate holder fixing step 420 which is formed on a side wall 401 and configured to separate the seal

Abstract: The present invention relates to a dual-chamber pack with a first chamber comprising a container; and a second chamber comprising a reservoir, a biphasic connector, a plunger, and a plug with a breakable polymeric membrane. The container of the first chamber is prefilled with a pharmaceutically acceptable vehicle and the reservoir of the second chamber is prefilled with a solid composition of an active ingredient, wherein the solid composition of the active ingredient is mixed with the pharmaceutically acceptable vehicle to form a liquid pharmaceutical composition upon activation of the dual-chamber pack.

Abstract: The subject matter described herein includes apparatus's and methods for storing and mixing materials such as powders and liquids. The mixing apparatus can comprise an impeller portion configured to rotate downward or upward within the main cup, wherein a movement of the impeller portion downward or upward is capable of mixing the contained set of substances, wherein the impeller portion comprises a set of propeller blades, and wherein the impeller portion is connected to a helical shaft portion comprising a first helical strand and a second helical strand wound uniformly in a parallel spiral configuration. The impeller portion facilitates a distributed mixing of the substances and the propeller blades are capable of removing deposits of the substance around the base of a main cup of the apparatus.

Abstract: The present invention relates to a dual-chamber pack for a multi-dose oral liquid pharmaceutical composition wherein the compositions of the first and second chambers are mixed at the time of first administration.

Abstract: The present invention relates to extended release liquid compositions of guanfacine. The extended release liquid compositions of the present invention are bioequivalent to marketed extended release tablet compositions of guanfacine. Said extended release liquid compositions provide substantially similar in-vitro dissolution release profile upon storage for at least seven days. Further, the extended release liquid compositions are stable. The extended release liquid compositions are in the form of ready-to-use liquid compositions or reconstituted liquid compositions. It also relates to processes for the preparation of said extended release liquid compositions.

Abstract: The present invention comprises an impurities or materials trapping apparatus for separating or trapping a selected or unwanted materials such as sediment in a pourable material having sediment therein. The apparatus comprises a body having side walls between a first end and second end defining at least a recessed inner space 42, 104, 204, 286 there between for a pourable material. The apparatus includes at least one raised portion 50, 51, 55, 56, 206, 208 having a highest point, angled walls 26 connected to the side walls 7, 40 202, 220, 282 and at least one drainage aperture 16, 110, 210 located within the side walls 7, 40, 202, 220 282 or angled walls 26, 103, 203, 284. The raised portion is located at one end of the inner space and the angled walls 26 are located at a spaced distance from the raised portion.

Abstract: A multi-chamber shot container including a hand-held body that defines a first aperture disposed at an upper end of the hand-held body, a second aperture, and an upper fluid aperture disposed at the upper end of the hand-held body, wherein the first aperture and the upper fluid aperture are disposed at the upper end of the hand-held body. The shot container also includes an inner container member with an inner surface and a bottom surface enclosing and defining a first cavity spanning from the bottom surface of the inner container member to the upper fluid aperture and an outer container member with an inner surface and a bottom surface enclosing and defining, with an outer surface of the inner container member, a second cavity liquidly segregated from the first cavity, wherein the first and second apertures are in sole fluid communication with the second cavity.

Abstract: Systems, methods, and articles for providing an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition on surface a cap element transfers antimicrobial to the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial.

Abstract: The subject matter described herein includes apparatus's and methods for storing and mixing materials such as powders and liquids. The mixing apparatus can comprise an impeller portion configured to rotate downward or upward within the main cup, wherein a movement of the impeller portion downward or upward is capable of mixing the contained set of substances, wherein the impeller portion comprises a set of propeller blades, and wherein the impeller portion is connected to a helical shaft portion comprising a first helical strand and a second helical strand wound uniformly in a parallel spiral configuration. The impeller portion facilitates a distributed mixing of the substances and the propeller blades are capable of removing deposits of the substance around the base of a main cup of the apparatus.

Abstract: The invention provides a mixing container comprising: a liquid holding vessel having first and second chambers each for holding a different liquid; a mixing unit having a first valve and a second adjustable valve, the second adjustable valve having an opening that can be partially closed to permit a pre-determined portion of liquid from each chamber to be dispensed when pouring from the mixing container; and the second valve including a series of teeth around the periphery thereof for engaging an adjustment wheel in the mixing unit to open or close the opening in the second adjustable valve.

Abstract: The present invention relates to oral liquid compositions of guanfacine. The liquid compositions can be immediate release or extended release compositions. The compositions comprise guanfacine in a concentration from about 0.1 mg/mL to about 12.0 mg/mL of the composition. The liquid compositions can be in the form of ready-to use liquid compositions or reconstituted liquid compositions. It further relates to processes for the preparation of said oral liquid compositions.

Abstract: The present invention relates to a method for preparing a stable extended release suspension composition comprising multiple coated cores of an active ingredient by using a suspension base, wherein the suspension base ensures substantially similar in-vitro dissolution release profile of the active ingredient upon storage of the suspension compositions for at least seven days.

Abstract: Cooling assemblies having a sealable cooling chamber formed as the interior volume of a curved or spherical outer container and a sealable inner canister are disclosed. The outer container may be provided as a multi-layer container having an external elastomeric shell. The external elastomeric shell may have an inner framework including a plurality of longitudinal ribs and a reinforcing wall. A movable flap adjustable between a projecting condition in which the flap extends from the exterior surface of the outer container and a closed position in which the flap doesn't project may be provided for supporting the cooling assembly in a stationary condition and the flap may be used as a handle for opening a lid.

Abstract: A combination container for a consumer product consisting of a body providing a primary compartment for containing a primary product, the body having a sidewall, a secondary compartment forming a cavity recessed into the body, one or more secondary products pre-packaged in a secondary product package being located within the cavity of the secondary compartment and a label over the secondary product package.

Abstract: A medication dispensing system includes a fluid and a plurality of pills. A bottle is provided and the fluid is contained within the bottle. The bottle has an outer wall and an inner wall. The inner wall defines a plurality of compartments with respect to the outer wall. Each of the compartments is fluidly discrete from an interior of the bottle. Each of the pills is removably positioned within an associated one of the compartments and each of the pills may be selectively consumed in conjunction with the fluid.

Abstract: A container (10) for dispensing a liquid beverage concentrate is provided. The liquid beverage concentrate is formed of a first beverage component, disposed in a body (12), and a second beverage component, disposed within a cartridge (30) at least partially within the body, that are initially isolated. The first and second beverage components can be combined to form the liquid beverage concentrate by moving the cartridge, such as further into the body, to unblock a flow path (36) between the cartridge and the body.