Abstract: A container includes a container portion having a storage space in which contents are stored, a spout coupled to the container portion and through which the contents in the container portion are discharged, and a nozzle configured to discharge the contents in fixed amounts, wherein the contents enter the nozzle from the head portion, and the spout and the nozzle are integrally formed.

Abstract: The device for packaging and dispensing a product comprises a container (1) intended to contain in a sterile manner the product to be packaged and dispensed in the form of calibrated doses or drops by means of a dispensing accessory equipped with a mouthpiece (4) of the type having a flexible part (5), said accessory forming a dosing chamber (7) for the dispensing of the calibrated drop. An outer wall (8) of the mouthpiece delimits a space (18) equipped with one or more openings (19), the end of said mouthpiece (4) including a central channel (13) allowing the dispensing of the calibrated drop, associated with one or more lateral channels (11) leading into the space (18). A cover (14) equipped with an inner skirt (15), in the mounted state, creates an overpressure so as to eliminate any residual drop (10) which can subsist in the mouthpiece (4) at the end. Application to the dispensing of doses of sterile products, particularly of drops in ophthalmology.

Abstract: The device makes it possible to dispense predetermined metered quantities of liquid. It includes a sealing member that can take up a liquid release position, allowing liquid to flow out of the device, and a non-return position preventing liquid from flowing back into the device. The sealing member is provided with metering means for metering out the liquid to be dispensed.

Abstract: Arrangements are provided for “smart” functionality with “dumb” containers, such as for tracking medication use to determine adherence. An acoustic emitter such as a whistle is engaged with a container such as an eye drop bottle. An event such as dispensing medication or opening the container causes a characteristic acoustic emission, such as an ultrasonic pitch of specific frequency. The emitter may be purposefully configured to produce the emission, may operate so that the emission is a natural consequence of dispensing medication (or other event), and may operate transparently to the user. The emitter may be part of a larger remote, such as a squeezable air-filled shell with an aperture to accept the container. A cell phone or other station receives the acoustic emission, and if a processor thereof determines that the emission is characteristic of the emitter the event is recorded, transmitted, displayed, or otherwise registered.

Abstract: Provided is a tube-type cosmetic container which discharges a liquid content in a form of droplet. The tube-type cosmetic container reduces the cost burden in accordance with shortening of the manufacturing time and reducing cost, by allowing a liquid content to be discharged in a form of droplet through a simple content discharging structure that becomes gradually wider from a lower portion to an upper portion thereof.

Abstract: A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.

Abstract: A dispense tip constructed and arranged to communicate with a material dispensing pump comprises an elongated neck and a molded base having a first portion and a second portion opposite the first portion. The neck extends from the first portion of the base. The second portion is constructed and arranged to abut an outlet surface of the pump. An outermost region of the second portion of the base includes a compressible fluid-tight surface that compliantly conforms to the outlet surface when the dispense tip is mounted to the pump.

Abstract: A grindstone tool is provided with a shaft part which has a tubular shape having a connection hole therein, a head part which has a cylindrical shape coaxially and integrally connected to the leading end of the shaft part and having a hollow section therein, and abrasive grains which adhere to the entire outer peripheral surface of the head part via a bonding material. A grinding fluid is supplied to the hollow section of the head part from one end side of the head part, the other end side of the head part is blocked by a lid member, and in the head part, a plurality of communication holes through which the hollow section and the outer peripheral surface communicate with each other, and which each have a taper shape with a diameter size on the outer peripheral surface side larger than a diameter size of the shaft center side are formed.

Abstract: Provided is a pipette tip having a visual indicator capable of confirming depth of liquid in contact with the pipette tip during a suction work. In the pipette tip, a marker-is formed on an outer surface of the pipette tip in a circumference direction in a tip end area in a tip end side for confirming the depth of liquid in contact with the pipette tip. Thereby, the depth of liquid in contact with the pipette tip is confirmed based on the marker directly or relatively.

Abstract: A device for dispensing liquid including an opening for dispensing liquid, a pad for absorbing residual liquid and a removable cap including a shape in the immediate vicinity and opposite the dispensing opening, referred to as a shape for expelling residual liquid, configured to discharge the residual liquid toward the pad when the cap is mounted on the device.

Abstract: Aspects of the present invention relate to systems, methods and apparatus for converting a container into a smart bottle. According to a first aspect of the present invention, a smart-bottle apparatus may comprise a container portion comprising a plurality of individually addressable sensor pairs covering the wall of the container portion. According to a second aspect of the present invention, a smart-bottle apparatus may comprise a container portion comprising a plurality of individually addressable sensor pairs covering a neck portion of the container portion.

Abstract: The present invention relates to a funnel comprising: a funnel body, where said funnel body includes an inner layer and an outer layer, and where said funnel body is made of a flexible material; a wide first opening and a wide second opening, where the first opening is larger than the second opening, and where the first opening has a curved portion and a planar portion; and an outwardly extending curved lip disposed on the rim of the first opening.

Abstract: [Object] To provide a method and apparatus for discharging a liquid material, which can solve the problems regarding the occurrence of a satellite and accuracy of a landing position. [Solving Means] In a method for discharging a liquid material in the state of a liquid droplet through a discharge orifice by applying inertial force to the liquid material, the method is characterized in comprising the steps of measuring a distance A from a lower end of the discharge orifice to a lower end of the liquid material having flowed out from the discharge orifice at the time when the liquid material having flowed out from the discharge orifice separates from the discharge orifice, and setting a distance B between the lower end of the discharge orifice and a work surface to be approximately the same as the distance A. An apparatus for carrying out the method is also provided.

Abstract: In one aspect, an adhesive dispensing system 30 includes a dispensing module 32 having an inlet and an outlet, a supply 35 of hot melt adhesive maintained at low pressure, and a low pressure liquid passageway 44 communicating between the supply 35 and the inlet of the dispensing module 32. Liquid material is received through the inlet at a low pressure, and the dispensing module 32 rapidly develops high pressure at the outlet 78 to jet the liquid material from the outlet 78. In another aspect, an apparatus for jetting liquid material includes a dispenser body 38 having a liquid chamber 40. A piston 54 is movably disposed within the liquid chamber 40, from a position wherein a piston tip 58 is spaced from a complimentary shaped recess 76, to a position wherein the piston tip 58 effectively seals off the recess 76, then to a position wherein the piston tip 58 is received within the recess 76 to displace a discrete volume of liquid material from the recess 76.

Abstract: [Object] To provide a method and apparatus for discharging a liquid material, which can solve the problems regarding the occurrence of a satellite and accuracy of a landing position. [Solving Means] In a method for discharging a liquid material in the state of a liquid droplet through a discharge orifice by applying inertial force to the liquid material, the method is characterized in comprising the steps of measuring a distance A from a lower end of the discharge orifice to a lower end of the liquid material having flowed out from the discharge orifice at the time when the liquid material having flowed out from the discharge orifice separates from the discharge orifice, and setting a distance B between the lower end of the discharge orifice and a work surface to be approximately the same as the distance A. An apparatus for carrying out the method is also provided.

Abstract: A dropper (10) for dispensing drops of a fluid from a container includes a dropping channel (12), which has a dropping channel inlet (13) for introducing the fluid into the dropping channel (12) and a dropping channel outlet (14) for dispensing drops from the dropping channel (12). The dropping channel (12) has a conical channel area (16) and a cylindrical channel area (15). The dropping channel inlet (13) is designed as an end of the cylindrical channel area (15), facing away from the conical channel area (16). To make it possible to better meter the quantities of drops that can be dispensed and to markedly reduce the dispensed quantities, the dropping channel outlet (14) is designed as an end of the conical channel area (16), facing away from the cylindrical channel area (15).

Abstract: A vessel for use in rinsing a user's nasal cavity provides a resiliently collapsible main body, a self-sealing nozzle that increases in internal pressure when the vessel is squeezed, and a check valve in the nozzle to reduce back-wash into the vessel. A collar connects the nozzle and check valve to the main body. The check valve includes a first opening that provides fluid communication between the main body and a void formed in an interior of the nozzle and may allow pressure within the nozzle to increase upon deforming the main body. A second opening may provide fluid communication between an exterior of the main body and a fluid reservoir formed in the main body. The second opening may cooperate with a valve that allows selective fluid communication between the exterior of the main body and the reservoir formed in the main body.

Abstract: [Problems] To provide an ejection container capable of falling a liquid in drops from the container body without relying on the sense of the fingertips and without affected by a change in the temperature. [Means for Solution] A knock-type ejection container 1 in which an ejection port 8 is provided at one end of a container body 2, a knock button 4 is provided at the other end thereof, a container chamber 22 is provided in the container body 2 to contain a liquid, and the liquid contained in the container chamber 22 is ejected from the ejection port 8 being interlocked to the operation of the knock button 4.

Abstract: Compositions comprising an antimicrobial effective concentration of sucralose and methods of using for treating pharyngeal and other bacterial conditions.

Abstract: The present invention relates to a bottle for packaging a liquid to be distributed drop by drop comprising a reservoir the walls of which can be reversibly elastically deformed by letting air into the container, surmounted by a liquid dispensing head comprising a dropper nozzle protruding from the bottle and an anti-bacterial filter membrane, that is partially hydrophilic and partially hydrophobic, interposed across the path of the liquid and the air, at the base of the said nozzle. In the dispensing head, the proposal is to create the nozzle by itself out of a material containing a bactericidal agent that has the effect of preventing any bacterial growth on the surface of the said nozzle on the outside of the antibacterial membrane. A porous core is advantageously positioned inside the duct through which liquid is expelled and air is admitted.

Abstract: The present invention relates to an insert (5) for a tube (1) for dispensing liquid content in the form of drops, wherein the insert (5) comprises at least one notch (16; 17) at its outer wall, with the notch (16; 17) extending in the longitudinal direction, wherein the insert (5) is provided with an annular indentation (10), the annular indentation (10) dividing the insert into a proximal part (7) and a distal part (8) that are connected by a shaft (9), wherein both the proximal part (7) and the distal part (8) comprise a notch (16; 18) extending in the longitudinal direction on the respective outer wall, and wherein the outer diameter of the proximal part (7) and the outer diameter of the distal part (8) of the insert (5) are such that they match the inner diameter of a spout (2) of a tube (1), into which the insert (5) shall be placed. The invention further relates to a tube (1) with such an insert (5).

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: The present invention relates to a droplet discharge apparatus that includes a nozzle for discharging a droplet from a tip thereof, and a discharge unit for injecting a gas toward the tip of the nozzle.

Abstract: A bottle for the creation, storage, administration and dispensing of elemental iodine is disclosed. An amount of crystal iodine is safely housed at the bottom of the bottle. Water is poured into the bottle and contacts with the crystal iodine to form elemental iodine. With the crystal iodine safely secured at the bottom of the housing, the formed elemental iodine maintains contact with the crystal iodine to maintain its stability and extends is shelf life. Several dispensing device are also disclosed for dispensing or administering the elemental iodine, as needed, in order to treat internal and external areas of a human's or animal's body.

Abstract: The liquid material discharge device and method discharges a liquid droplet even under a condition where discharge of a small amount of liquid material is required. The apparatus has a liquid chamber having the discharge opening through which the liquid material is discharged, an extrusion member having a plunger and a contact portion, the plunger being thinner than the liquid chamber not to contact a side wall of the liquid chamber and having a forward end portion which advances and retracts within the liquid chamber, and a collision member disposed adjacent to the extrusion member on the side opposite to the plunger and having a piston and a collision portion facing the contact portion. The collision portion collides against the contact portion such that the extrusion member is advanced at a high speed to discharge the liquid material.

Abstract: An example of droplet discharge device includes a discharge path (12) having an end that constitutes a discharge opening (11), a plunger (30), a liquid chamber (50) into which the plunger (30) is inserted, a plunger driving mechanism that moves the plunger (30) forward and backward, and a plunger position determining mechanism that specifies a position of a tip portion of the plunger (30). The liquid material is discharged in a droplet state by applying inertial force to the liquid material with forward movement of the plunger (30) in a state where the tip portion of the plunger (30) and an inner wall of the liquid chamber (50) are not contacted with each other. A minute droplet is formed by moving the plunger (30) forward to push the liquid material out of the discharge opening (11) in an amount necessary to form a droplet of a desired size.

Abstract: A gaseous fuel internal combustion engine includes an engine housing defining at least one cylinder, and an intake housing defining an intake passage fluidly connecting with the at least one cylinder. The engine includes a gaseous fuel delivery mechanism coupled with the engine housing and a distributed ignition promoting mechanism having a bead presentation device extending into the intake passage and configured to present a liquid bead of distributed ignition promoting material therein such as engine lubricating oil. During operation, gases passing through the intake passage dislodge the liquid bead from the bead presentation device and carry the distributed ignition promoting material into the cylinder for distributively igniting therein a mixture containing a gaseous fuel, air and the distributed ignition promoting material.

Abstract: Drop dispenser for releasing a pharmaceutical liquid in drop form, with a housing, a liquid storage and a discharge opening, which penetrates a wall of the housing and to which an outlet valve is assigned, for extracting the liquid. The discharge opening is surrounded by a drop-formation area on the outside of the housing, wherein this drop-formation area, at least in an outer region with respect to an alignment of the drop dispenser with the discharge opening pointing vertically downwards, has a shape tapering downwards and towards the discharge opening. The drop dispenser allows the release of drops with a constant size and shortens drying time.

Abstract: An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween.

Abstract: A dispenser for applying small amounts of liquid to a substrate. The dispenser includes a dispenser body, an actuator in the dispenser body, and a dispensing element including a dispensing element body removably coupled to the dispenser body. A valve stem is mounted for reciprocating movement within the dispensing element body. Additional aspects include a deformable valve seat, a deformable and resilient valve stem tip and a method of applying liquid in discrete amounts to a substrate.

Abstract: A tip arrangement for a bottle used for dispensing viscous liquid, such as drops of medicine, is provided. Embodiments include a tip insert having an insert body and a piercing point at a lower end of the insert body, for piercing a top surface of the bottle and for retaining the tip insert on the top surface of the bottle after piercing. A passage extends from a distal end of the piercing point, through the insert body, to an opposing upper surface of the insert body. A dispensing tip at the insert body upper surface communicates with the passage for precisely forming drops of the liquid from the bottle.

Abstract: A dispensing container according to the invention includes a container body having a rod-like shape. The dispensing container is therefore compact and the user can hold the dispensing container as if the user holds a pen and use the thumb, the index finger, and any other finger to apply pressure to the dispensing container so as to dispense a drug solution. A heat insulating grip is attached to the outer circumferential surface of the container body, whereby heat originating from the body temperature of a finger of the user will not be transferred to the drug solution or volatilize it. No excessive dispensing that is not intended by the user will therefore occur. Since the container body is thin and hence unlikely crashed, the user can make adjustment of the pressure applied by the thumb, the index finger, and any other finger to readily extract a single droplet.

Abstract: A liquid dispensing device including a sealing component which can take up a liquid release position and a liquid blocking position. The sealing component includes an elastomer part and a rigid part, these parts being fastened to each other when moving.

Abstract: The invention relates to a device for the actively-controlled deposition of microdrops of biological solutions. The inventive device includes at least one flat silicon lever comprising a central body and an end area which forms a point, a slit or groove being disposed in said point. The invention is characterized in that it also comprises at least one metallic track which is disposed on one face of the central body and which runs alongside said slit or groove at least partially. The invention also relates to a method of producing the inventive device and a method for the active-controlled deposition and sampling of microdrops of biological solutions using said device.

Abstract: A droplet interference system for sorting cells and a method for the same. The droplet interference system including a droplet generating system for producing a droplet which hits a fluid stream causing a selected segment of the fluid stream, and the cells contained therein, to be separated from the fluid stream.

Abstract: A specimen sorter includes a separating device to remove a specimen from a container, a detection device to identify the specimen as a target specimen or a non-target specimen, and a dispensing device to dispense the specimen. The dispensing device includes a dispensing nozzle to contact a vibration member to form liquid droplets at a front end of the dispensing nozzle and to dispense the liquid droplets, a first container to collect the liquid droplets dispensed from the dispensing nozzle that contain the target specimen, and a second container to collect the liquid droplets dispensed from the dispensing nozzle that contain the non-target specimen.

Abstract: A dispensing device for dispensing liquid media having a housing, an outlet opening for the medium, a medium reservoir for storage of the medium and a conveying device for transporting the medium from the medium reservoir to the outlet opening, wherein a flow brake is provided in a medium duct between the conveying device and the outlet opening. The flow brake has a first flow brake component which can be arranged and fixed relative to the housing or to a second flow brake component during assembly in several differing relative positions, wherein differing flow resistances of the flow brake are achieved depending on the selected relative positions.

Abstract: The liquid material discharge device and method discharges a liquid droplet even under a condition where discharge of a small amount of liquid material is required. The apparatus has a liquid chamber having the discharge opening through which the liquid material is discharged, an extrusion member having a plunger and a contact portion, the plunger being thinner than the liquid chamber not to contact a side wall of the liquid chamber and having a forward end portion which advances and retracts within the liquid chamber, and a collision member disposed adjacent to the extrusion member on the side opposite to the plunger and having a piston and a collision portion facing the contact portion. The collision portion collides against the contact portion such that the extrusion member is advanced at a high speed to discharge the liquid material.

Abstract: A microchannel structure including a dispersed-phase introduction channel which communicates with a dispersed-phase introduction inlet; a continuous-phase introduction channel which communicates with a continuous-phase introduction inlet; a discharge channel which communicates with a discharge outlet; a fine-particle formation channel; and a plurality of branch channels for dispersed-phase introduction which are microchannels; wherein one end of the fine-particle formation channel in a fluid traveling direction communicates with the continuous-phase introduction channel whereas the other end thereof communicates with the discharge channel; and wherein a side part of the dispersed-phase introduction channel and side part of the fine-particle formation channel communicate via the plurality of branch channel for dispersed-phase introduction.

Abstract: A credit card shaped container for a liquid, such as eye drops, saline solution, or a sanitizer. The container has a generally flat, rectangular, flexible plastic body having an inner chamber capable of storing the liquid. A conduit supplies liquid in the chamber to a dispensing orifice at an end portion of the body. A cap attached to the body and covering the dispensing orifice prevents the liquid from being dispensed until the cap is removed and pressure applied to the flexible plastic body. The cap may be hingedly attached to the body, or completely detachable from the body. The cap typically snaps over the orifice and seals the conduit closed. The container may further comprise an integral contact lens case.

Abstract: A device for dispensing liquid contained in a container, the device including an elastomer element that can take up: a liquid release position allowing liquid to flow out of the device; and a non-return position preventing liquid from flowing back into the device; the device further including a bearing mechanism against the elastomer element in register with a recessed zone, serving to deform the elastomer element in its non-return position.

Abstract: [Problems] To provide an ejection container capable of falling a liquid in drops from the container body without relying on the sense of the fingertips and without affected by a change in the temperature. [Means for Solution] A knock-type ejection container 1 in which an ejection port 8 is provided at one end of a container body 2, a knock button 4 is provided at the other end thereof, a container chamber 22 is provided in the container body 2 to contain a liquid, and the liquid contained in the container chamber 22 is ejected from the ejection port 8 being interlocked to the operation of the knock button 4.

Abstract: The liquid material discharge device and method discharges a liquid droplet even under a condition where discharge of a small amount of liquid material is required. The apparatus has a liquid chamber having the discharge opening through which the liquid material is discharged, an extrusion member having a plunger and a contact portion, the plunger being thinner than the liquid chamber not to contact a side wall of the liquid chamber and having a forward end portion which advances and retracts within the liquid chamber, and a collision member disposed adjacent to the extrusion member on the side opposite to the plunger and having a piston and a collision portion facing the contact portion. The collision portion collides against the contact portion such that the extrusion member is advanced at a high speed to discharge the liquid material.

Abstract: This assembly is of the type including: a vessel (4) for containing liquid, the vessel (4) having a neck (14); a dispensing dropper end fitting (6) disposed at the end of the neck (14); and a cap (8) for closing the vessel (4), provided to be screwed onto the neck (14). In a preferred embodiment, the cap (8) and the neck (14) have safety element preventing the cap (8) from being unscrewed simply by applying an unscrewing torque, and allowing the cap (8) to be unscrewed when an additional action is applied together with the torque for unscrewing the cap (8).

Abstract: Drop dispenser for releasing a pharmaceutical liquid in drop form, with a housing, a liquid storage and a discharge opening, which penetrates a wall of the housing and to which an outlet valve is assigned, for extracting the liquid. The discharge opening is surrounded by a drop-formation area on the outside of the housing, wherein this drop-formation area, at least in an outer region with respect to an alignment of the drop dispenser with the discharge opening pointing vertically downwards, has a shape tapering downwards and towards the discharge opening. The drop dispenser allows the release of drops with a constant size and shortens drying time.

Abstract: The present invention relates to packaging materials for ophthalmic solutions. Difficulties with water loss in standard ophthalmic bottles are overcome in the controlled drop dispensing container of the present invention. This controlled drop dispensing container comprises a dispensing tip, a laminate tube 15, and a shoulder connecting the laminate tube 15 to the dispensing tip 7. The dispensing tip 7 comprises an inner orifice having a diameter sufficiently small to restrict flow of liquid contents of the tube to the desired level, an outer orifice 9 having a diameter sufficiently large to form a drop of the desired size from the liquid contents of the tube, where fluid communication exists between the inner orifice and the outer orifice 9. The laminate tube 15 comprises an outer polymeric layer 10, an optional first tie layer 11, a middle barrier layer 12, an optional second tie layer 13, an inner polymeric layer 14.

Abstract: Various embodiments of the present invention are directed to droppers that can be used at nighttime or in low-light conditions.

Abstract: A container-closure system includes a sterile vessel configured to store a preservative-free therapeutic agent. A polymeric applicator is fluidly coupled to the vessel through which the therapeutic agent is dispensed. Surfaces of the applicator that are susceptible to contamination during dispensing of the therapeutic agent comprise one or more antimicrobial additives which provide antimicrobial efficacy at the applicator surfaces.

Abstract: The present invention relates to a metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop comprising: (a) a bottle with a flexible portion on the walls to decrease the internal volume by a fixed volume; (b) a plunger with a fixed stroke for depressing the flexible portion of the walls of the bottle; and (c) a nozzle tip having an internal and/or outer diameter no more than 1.2 mm.

Abstract: The particulate material production method includes vibrating a particulate material composition liquid in a liquid column resonance chamber having at least one nozzle to form a standing wave in the particulate material composition liquid caused by liquid column resonance, so that droplets of the particulate material composition liquid are ejected in a droplet ejection direction from the nozzle so as to fly in a space in a flight direction; feeding a gas in a direction substantially perpendicular to the droplet ejection direction to change the flight direction of the ejected droplets; and solidifying the droplets in the space to produce a particulate material. The particulate material composition liquid includes at least a solvent and a component of the particulate material dissolved or dispersed in the solvent, and the nozzle is located at a location corresponding to an anitnode of the standing wave.