Abstract: The invention pertains to a capsule system for use with a medical device designed to administer atomized medication to patients. The system features a chamber containing the medication and an atomizer at a lower end for efficient drug delivery. Notably, the system incorporates a fluid sensor and electrical contacts to ensure proper operation and medication delivery. The capsule's design includes a housing with an asymmetrical transverse cross-sectional shape for unique fitting, and a tapered wall to direct medication towards the atomizer. The capsule may also connect to an external container or include a stopper for refilling medication. A specific embodiment features two chambers with a rupturing element to facilitate medication transfer. Another embodiment includes a removable container, like a vial, within the first chamber. This novel system provides improvements in accuracy, versatility, and user-friendliness, overcoming limitations in prior art.

Abstract: The disclosed technology includes dispensing systems, devices, and methods. The dispensing systems include a plurality of sealing components, and a plurality of coupling mechanisms. In one embodiment, a dispensing device, including a first unit having a top wall and an inner cylindrical projection extending from a bottom face of the top wall and a second unit having an outer cylinder, is adapted to be received by a receptacle. The inner cylinder receives the inner cylindrical projection and the outer cylinder receives the receptacle. A breakable seal closes an opening of the inner cylinder to form a chamber portion for storing a substance. Protruding seals on the inner cylindrical projection bear on the inner cylinder. An application of force to the top wall lowers the inner cylindrical projection to disrupt the breakable seal and release the substance into the receptacle to mix with a liquid stored in the receptacle.

Abstract: A reusable dispensing device for dispensing contents into a container. The device including a body having a chamber configured to receive a capsule and configured to sit on an opening of the container. A portion of the body being movable between an unsealed first position and an engaged second position. Piercing means are configured to pierce the capsule, and sealing means are configured to seal the container in the engaged second position. Movement of the body from the unsealed first position to the engaged second position to seal the container engages the piercing means to pierce the capsule and dispense contents from the capsule into the container.

Abstract: The invention relates to a device (10) for preparing a cosmetic composition comprising:—a structure (28) defining a housing (30) receiving at least one capsule (16) containing at least one constituent of the cosmetic composition, —an outlet nozzle (32) at one end (34) of the housing (30), suitable for being fluidically connected to a receptacle, —a piston (36) movable in translation in relation to the structure (28), suitable for perforating the or each capsule (16) and conveying contents of each capsule (16) to the outlet nozzle (32). The device (10) comprises a system (90) for checking the capsule(s) (16) in the housing (30), suitable for determining whether the capsule(s) (16) arranged in the housing (30) are suitable for contributing to the preparation of the cosmetic composition.

Abstract: An over shoe for use with electrosurgical instruments having a pair of juxtaposed jaw members pivotably associated with one another, at least one of which includes an electrically conductive surface disposed thereon which is in electrical engagement with an electrosurgical energy source. According to one aspect of the present disclosure, the over shoe includes a tissue contacting wall configured and dimensioned to selectively and substantially overlie the electrically conductive surface of the electrosurgical instrument. The tissue contacting wall is fabricated from a non-conductive material and includes a plurality of apertures formed therethrough. In another embodiment, the tissue contacting wall is electrically conductive and is configured for selective engagement atop on of the jaw members.

Abstract: A container (1, 2) for storing and dispensing a liquid, the container including an access port (16) having a frangible seal (18) for allowing contained liquid to be dispensed. A vent (19) permeable to vapour but impermeable to liquid is also provided so that vapour may be vented from the interior of the container.

Abstract: An apparatus for delivering a volatile material in a continuous manner is disclosed. The apparatus includes a delivery engine having a reservoir for containing a volatile material; a rupturable substrate secured to the reservoir; a rupture element positioned adjacent to the rupturable substrate; and a breathable membrane enclosing the reservoir, rupturable substrate and rupture element. In some embodiments, the apparatus includes a housing having a notch for compressing the rupture element and breaching the rupturable substrate as it is inserted into the housing.

Abstract: Actuators, principally for inflating emergency-usage objects such as floats and rafts, are detailed. Two opposite positive actions may be required to effect complete inflation of the objects, inhibiting inadvertent deployment of, particularly, the rafts while readily permitting deployment when intended.

Abstract: A spike for dispensing fluids from a flexible bag, wherein the spike includes multiple fluid channels which transfer liquids from the bag to an enclosed dispensing chamber and air from the enclosed chamber to the bag to permit and control fluid flow within the system.

Abstract: An apparatus for delivering a volatile material in a continuous manner is disclosed. The apparatus includes a delivery engine having a reservoir for containing a volatile material; a rupturable substrate secured to the reservoir; a rupture element positioned adjacent to the rupturable substrate; and a breathable membrane enclosing the reservoir, rupturable substrate and rupture element. In some embodiments, the apparatus includes a housing having a notch for compressing the rupture element and breaching the rupturable substrate as it is inserted into the housing.

Abstract: A dispensing closure for a vessel comprising a base member and a spout member engaged with the base member. The base member including a rupture member having a camming surface and the spout member having a cam actuator for engaging the camming surface to rupture the rupture member during twisting of the spout member in a first direction relative to the base member from a sealed position to a flow position to define a flow opening in the base member to permit fluid flow through the flow opening. The dispensing closure may include a pair of spaced rupture members and cam actuators. The dispensing closure may include a cap member hingedly attached to the spout member. The dispensing closure may include tamper evidency ring or other structure and a locking mechanism configured to lock the cap member in the closed position until the cap member and spout are rotated a sufficient distance to break the tamper evidency ring.

Abstract: A spike for dispensing fluids from a flexible bag, wherein the spike includes multiple fluid channels which transfer liquids from the bag to an enclosed dispensing chamber and air from the enclosed chamber to the bag to permit and control fluid flow within the system.

Abstract: A system for dispensing fluids wherein a support structure holds bulk fluid contained within a bag that is transferred from the bag to an enclosed chamber in a dispensing base, from which chamber the fluid is dispensed, via a puncturing device utilizing multiple spikes. After dispensing air pressure in the enclosed chamber is equalized with the air pressure acting on the bulk fluid by at least one of the spikes.

Abstract: A dispensing device dispenses at least two different preparations substantially simultaneously. The device has a delivery element to deliver a first preparation from a package to its surrounding environment when an actuating element, in at least one embodiment a trigger connected to a pump, is actuated. The dispensing device has a connection line between the delivery element and at least one portion cartridge for a second preparation. The portion cartridge is detachably coupled to the dispensing device such that as the actuating element is actuated, the first and second preparations can be simultaneously dispensed.

Abstract: A portion container which can be unsealed easily by an extremely simple operation, and the lid of which can be opened easily with no possibility of scattering of the contents. The container body is constituted of a nonflexible tubular upper structure which is resistant to press deformation, and a flexible bottomed tubular lower structure extending downward from the lower edge of the upper structure and being susceptible to press deformation, wherein a press board connected rotatably with the upper structure and equipped with a cutter is provided vertically in the container. A lid plate is cut by pressing the press board from the outside to rotate the cutter.

Abstract: A system for dispensing fluids wherein a support structure holds bulk fluid contained within a bag that is transferred from the bag to an enclosed chamber in a dispensing base, from which chamber the fluid is dispensed, via a puncturing device utilizing multiple spikes. After dispensing air pressure in the enclosed chamber is equalized with the air pressure acting on the bulk fluid by at least one of the spikes.

Abstract: Devices and methods are disclosed for extracting fluids from within a container sealed by a cork or septum without removal of the cork or septum or the contamination of the fluid within the container by reactive gases or liquids. Embodiments of the device can include a needle connected to a valve which is in turn connected to a source of pressurized gas for displacing the fluid. Further embodiments of the device can comprise additional components that act to force the needle to be inserted through the cork or septum along a linear path, to aid in preventing buckling of the needle, to clamp the device to the container, to prevent expulsion of the cork or septum from the container, and to guide the needle through a specified region of the cork or septum. Various valves, pressure regulators, pressure ranges, needle geometries, gas selections are also presented. This device is particularly suited for the dispensing and preservation of wine.

Abstract: A system for dispensing fluids wherein a support structure holds bulk fluid contained within a bag that is transferred from the bag to an enclosed chamber in a dispensing base, from which chamber the fluid is dispensed, via a puncturing device utilizing multiple spikes. After dispensing air pressure in the enclosed chamber is equalized with the air pressure acting on the bulk fluid by at least one of the spikes.

Abstract: A beverage container (10) is disclosed having an outer housing (11), a discharge nozzle (12), one or more beverage chamber (18) and a plunger means that may be a base cup (14) with shaft members (50). Preferably there are two or three beverage chambers. The beverage container (10) may include a mixing nozzle (75). The device may include positioning for a travel position, initial discharge position and fully discharged position. The beverage chambers (18) may be separately filled and held in position by a sleeve (62) frangible seals and a safety cap may be included. The invention extends to a method of providing a beverage, preferably an alcoholic beverage to a consumer.

Abstract: The invention relates to a device for combining two components. A first container accommodates the first component, which is liquid, and a second container accommodates a second, solid or liquid component under negative pressure. A body is provided with a first holder for the first container, in the region of the closure of the latter, and with a second holder for the second container, in the region of the closure of the latter. Displaceable means for piercing the closures are provided within the body. In the case of such a device, the invention provides that the body has two slides mounted in a displaceable manner in it, wherein each slide accommodates a cannula for piercing the respective closure, the cannulas are connected, in the region of their ends directed away from the closure, to an element which connects the cannulas in a liquid-tight manner, and actuating means are provided for moving the slides in the direction of the closures for the purpose of piercing the closures.

Abstract: A mixing apparatus, puncturing mechanism, and cartridge are disclosed. The mixing apparatus has a housing and a drawer with a recess. Corresponding cartridges may be inserted into the drawer and slid into the housing to facilitate mixing a liquid with contents of the cartridge. The liquid may originate from a reservoir in the mixing apparatus or a direct line. Also inside the housing of the mixing apparatus is the puncturing mechanism. The puncturing mechanism has a nozzle configured to puncture a lid of a cartridge and inject liquid to mix with the contents of the cartridge. The puncturing mechanism is further configured to drive an internal puncturing unit inside of the cartridge through a lower portion of the cartridge to allow liquid from the nozzle and contents of the cartridge to be dispensed into a receptacle.

Abstract: A system and method for supplying bottled water to an appliance is provided, where the water bottle is opened as it is positioned on the appliance. The appliance includes an operational portion and a bottle receiving portion. The operational portion can be any appliance which utilizes water in its operations, such as humidifiers, vaporizers, coffeemakers, tea makers, dental water jets, and the like. The bottle receiving portion includes a conduit defining a fluid path, where the conduit is in fluid communication with the operational portion. The conduit has a first end with a piercing member for piercing the bottle, and a second end in fluid communication with the operational portion. When a water bottle is positioned in the bottle receiving portion, the piercing member pierces the bottle, allowing the water to exit the bottle along the fluid path to the operational portion of the appliance.

Abstract: A system for dispensing fluids wherein a support structure holds bulk fluid contained within a bag that is transferred from the bag to an enclosed chamber in a dispensing base, from which chamber the fluid is dispensed, via a puncturing device utilizing multiple spikes. After dispensing air pressure in the enclosed chamber is equalized with the air pressure acting on the bulk fluid by at least one of the spikes.

Abstract: An insecticidal activatable bait station including a base, the base having an integral structured reservoir provided therein, a series of piercing spikes extend upwardly from the base of the reservoir, and are provided for piercing the seal of a container holding a supply of liquid insecticide, to allow for the deposition into the base when prepared for usage. A series of columns extend upright form the base, holds the containerized liquid either in an elevated position, as during shipment, storage, display, or while awaiting its usage, but that when the liquid container is lowered, and pierced, the container is held into its lowered position, its seal having been pierced, for deposition of its liquid insecticide into the base reservoir, for consumption by any insects. Convenient ramps are provided to allow access through slots into the reservoir, when attracting any insect located nearby.

Abstract: A combination container and container cap (10) includes a container cap (11) having a deformable cover (14) on which a plurality of levers (15) are operatively connected. The levers (15) move from a first position to a second position, wherein the levers (15) move downward and radially outward to puncture a membrane (20) thereby allowing the substance in the container cap (11) to mix with a liquid (102) in a cavity (101) of a container (100).

Abstract: A closure mechanism for a beverage preparation machine comprising a fixed lower part, an upper part rotatable relative to the lower part and a cartridge holder interposed between the lower part and the upper part and being rotatable relative to the lower part and the upper part, wherein the lower part comprises inlet piercing means and outlet piercing means for forming, respectively, an inlet and an outlet, in use, in a cartridge received in the cartridge holder, wherein rotation of the upper part towards the lower part causes the upper part to engage the cartridge holder and to move the cartridge holder into contact with the lower part and at the same time to cause, in use, the inlet piercing means and the outlet piercing means to pierce a cartridge received in the cartridge holder.

Abstract: In a sterilizing agent capsule container and a sterilizer using the sterilizing agent capsule container where a vacuum sterilizing housing is filled with a chemical vapor obtained by the vaporization of a sterilizing agent to sterilize an object to be sterilized, a plurality of sealed sterilizing agent capsules are accommodated in the axial direction of a needle for removing a sterilizing agent in a capsule accommodation chamber of the sterilizing agent capsule container and the sealed sterilizing agent capsules are made of a material through which the needle can pass. A plurality of the sealed sterilizing agent capsules in the sterilizing agent capsule container can be gradually punctured by the needle in sequence.

Abstract: A flow controller for a container including a slide member guide, having a first peripheral flange on an outer surface, and configured to be either integral with the container or to be attached separately to a neck of the container. The neck includes a seal. A slide member is slideably and rotatably carried within the slide member guide. The slide member includes a second peripheral flange attached to an outer surface of the slide member to provide a space for insertion of a shipping pin between the first and second peripheral flanges. The shipping pin prevents an inner edge of the slide member from contacting and puncturing the seal. The container can include a lancing pin disposed on the inside of the container and is configured to contact the slide member at a top end and actuate an air vent at the opposite end.

Abstract: A reservoir for use with a dispensing appliance for spraying a liquid is provided, wherein the dispensing appliance comprises a protecting plate and at least two needles for engaging the reservoir. The protecting plate has a locked position and an unlocked position, wherein the protecting plate is movable in the unlocked position to expose the needles and is immovable in the locked position. The reservoir comprises a finish with an opening which communicates with the interior of the reservoir and a membrane disposed across the opening, wherein the membrane has an exposed length of less than about 45 mm.

Abstract: An isolated compensated fluid delivery system is used in an underwater vel, such as a torpedo, to deliver a supply fluid such as fuel, while displacing the supply fluid with a compensating fluid to compensate for change in buoyancy of the underwater vessel. The buoyancy compensated fluid delivery system includes a container, such as a fuel tank, a flexible delivery chamber disposed within the container adjacent a flexible compensation chamber. An outlet is coupled to the flexible delivery chamber and extends outside the container to direct the supply fluid out of the flexible delivery chamber. An inlet is coupled to the flexible compensation chamber and extends outside the container to direct the compensating fluid into the flexible compensation chamber as the supply fluid is being delivered. The volume of compensating fluid is substantially equivalent to the volume of supply fluid such that the weight and displacement of the underwater vessel remains substantially constant.

Abstract: An inflation system with pneumatic assist for a life raft or other inflatable article includes a puncture pin that is mounted to a slideably mounted piston. The puncture pin makes a small initial puncture in the membrane of a gas cartridge to start a trigger flow of compressed gas from the cartridge. That trigger flow travels through a gas passageway formed in the puncture pin and enters a cylinder within which the piston is mounted, driving the piston toward the membrane. A primary membrane cutter is carried by the piston, and the primary membrane cutter bursts through the membrane and unleashes a high volume flow of compressed gas into the article to be inflated. In a second embodiment, the primary membrane cutter is integrally formed with the puncture pin.

Abstract: A container for storing liquids such as ink to be refilled in an used, empty ink cartridge for computer printers being to be formed with at least two holes so as to allow the ink to discharge. A hole is made in the container at its mouth portion and then another hole is opened at the main chamber of the container by a piercing device attached to the container or by revealing an air passage so as to introduce external air into the container so as to pressure out the ink into the ink cartridge.

Abstract: A foil bag package, particularly for a mortar mass, includes at least one foil bag (1, 2) and a base part (3, 4) located at an end surface (1a, 2a) of the foil bag. The base part has an outflow passage (5, 6) for conveying the mortar mass through a discharge stub (7) from the foil bag (1, 2) and a piercing device for the foil bag. The piercing device has at least two piercing spatulas (8, 9) disposed in a parallel and laterally spaced relation and approximately parallel to the axis of the outflow passage (5, 6) and located within an axial projection of the outflow passage extending towards the foil bag.

Abstract: A flexible, hollow puncture and drainage boot for insertion of an oil filter therein. The puncture and drainage boot includes a ledge member upon which an end wall of a vehicle oil filter is placed, to provide a cavity space between an end base member of the drainage boot and the bottom of the oil filter for drainage of fluid therefrom, through at least one hole produced by a piercing of the oil filter. The drainage boot further includes an exit conduit for drainage of oil therefrom.

Abstract: A closure device for a container having an opening sealed with a membrane comprises: a cap adapted to engage the opening of the container for closing same and comprising a first cylindrical wall connected to one side of a circular base; and a membrane-penetrating element comprising a second cylindrical wall connected to the reverse side of the circular base and, within the second cylindrical wall, means for penetrating a membrane when the element is pressed into contact with the opening of a container sealed with the membrane, the means comprising a plurality of arciform cutters that are connected to the base and are coaxial with and in close proximity to the inner surface of the second cylindrical wall, the plurality of arciform cutters together comprising a total of at least 300 degrees.

Abstract: A closure of a double cartridge for a dispensing appliance comprises piercing members for piercing a membrane provided on the outlet openings of the cartridge, the piercing members including two stoppers which are tapered at their front sides. With the closure, it is possible when using the cartridge to pierce the membrane without searching for a suitable object and to reuse the cartridge without soiling.

Abstract: A pump for discharging the contents of a sealed container, such as a test tube, is connected to a body member which includes an inlet path and a discharge path with a delivery tube in the discharge path. A predetermined clearance is provided between the exterior of the delivery tube and the interior of the discharge path, the clearance providing venting, or blow-by, such that temperature changes do not cause accidental discharge of the contents of the container, while still maintaining sufficient resistance to venting for permitting pressurizing the interior of the test tube with the pump for accurately controlling the discharge of the test tube contents. A second or supplemental vent is provided in the pump.

Abstract: A method and apparatus for metering and dispensing an active ingredient, such as an insecticide, fumigant, fertilizer or room freshener. The active ingredient is placed in a container 6 and a pressurized propellant is subsequently introduced from a source 1 via conduits 3, 9. The propellant serves to absorb the active ingredient which is dispersed from the container via conduit 5 through a dispensing outlet 8 so that the active ingredient is dispersed in an airborne dispersion. In an ejector 4, a pressure differential is created across a propellant inlet port 4a which is sufficient to draw the active ingredient from the active ingredient container 6 but is less than the pressure differential required to cause a cooling effect in the mixing chamber 4 and is less than that pressure differential that gives rise to an erratic dispersion of the active ingredient from the dispensing outlet 8. The system is particularly suitable for the spraying of insecticides into large spaces such as warehouses and supermarkets.

Abstract: A spraying device having a sprayer head and an interchangeable, disposable, recyclable and/or biodegradable, and attachable cartridge, capable of diluting and dispensing a chemical. The device has a rotatable barrel valve to select whether to fill the cartridge, spray the diluted chemical, or prevent any flow. The device further has a pair of coupling tubes which permit the easy connection of the sprayer head to the cartridge in a way to cause, by aspiration, the partially diluted chemical to enter the sprayer head for further mixing and discharge. A rupturable or replaceable membrane is placed across the top of the cartridge to contain the concentrated chemical prior to use. A plug closure permits the addition of a chemical to the cartridge.

Abstract: A device for withdrawing flowable filling material through a wall of a bag having flexible walls, comprising a first member having a throughbore and an annular sealing surface surrounding the throughbore, a second member having an annular sealing surface and separating means formed radially inwardly of the sealing surface to cut a bag wall, the first and the second member including cooperating locking means which enter into an interlocking engagement when the separating means makes two cuts through the wall forming the bag. The annular sealing surfaces of the first and the second member are brought into sealing engagement to outer surface of the bag wall, whereby the first and the second member, each, are adapted to be brought into sealing engagement with the outer surface of the wall forming the bag.

Abstract: An apparatus for discharging the contents of a sealed container, such as a test tube, includes an inlet path and a discharge path with a delivery tube in the discharge path. A predetermined clearance is provided between the exterior of the delivery tube and the interior of the discharge path, the clearance providing venting, or blow-by, such that temperature changes do not cause accidental discharge of the contents of the container, while still maintaining sufficient resistance to venting for permitting pressurizing the interior of the test tube for accurately controlling the discharge of the test tube contents.

Abstract: Chemical dispensing apparatus for emptying and rinsing containers of chemicals, with dilution of chemical. The apparatus includes a chamber in which the container can be enclosed and supported, draining means provided at a lower portion of said chamber and a hollow perforated wash pipe mounted on the chamber so as to be moveable into the interior thereof to pierce twice any container supported therein, the wash pipe being connected to a diluent supply. The chamber is provided with means for supporting the container in a generally tilted manner such that a corner thereof is presented as the lowest portion and the wash pipe is arranged to pierce the container through said corner, means being provided on the wash pipe to hold apart the lowest pierced portion of the container and one or more nozzles being provided to spray diluent over a substantial part of the interior of the container while the pierced portion is held apart.

Abstract: An improved device for aspetic dispensing of enteral feeding solutions from shape retentive, pre-filled containers. The device including a distensible hanger member formed around only the end panels of the container to suspend the container in an orientation to define only a single uppermost corner and a single lowermost corner. The device further including corner attachment members for firmly securing a therapeutic fluid dispensing column only to the uppermost and lowermost corners of the container. The fluid dispensing column having venting and dispensing spikes. The spikes having an outer configuration which forms leak-proof seals with an aperture formed in the container. The spikes further including an arrangement of laterally opposed inlet ports joined to a large diameter axial bore.

Abstract: A multiple compartment container and closure assembly with a container having at least two adjacent compartments with end portions terminating in a common surface at one end of the container. The end is sized to accept a cap and the surface has a thin wall portion in communication with each of the compartments. A cap is sized to slidably fit on the end of the container which has puncture means being positioned in alignment with each of the thin wall portions of the container so that movement of the cap from a first position on the end to a second position causes the puncture means to puncture the respective thin wall portion with which it is aligned, to permit access to the contents of the adjacent compartments.

Abstract: A carton pourer attachment for a carton of "gable top" type, which has two conduits, one a breather conduit and a second a pourer conduit that are attached to the top of a common support which has two dependent legs adapted to grip the carton sides during a piercing action; and the pourer conduit has a tongue adapted to push away from a sealing position any tab cut from the top of a carton and also provide an interlocking with a middle lip of the carton to resist removal of the attachment.

Abstract: A processing apparatus with several liquid stations for the wet processing of image-wise exposed photographic elements, e.g. sheets, wherein the different processing liquids are provided in different liquid compartments (85, 86, 87) of the processing cassette (72), that has openings (88,89,90,91) that are sealed by membranes (92), and wherein the rinsing water compartment is provided with perforate partitions (94) with a scavenging agent for removal of fixing agent ions and complexed silver ions from the rinsing water in said compartment.

Abstract: A dispensing device formed of a cradle for receiving a brick pack. The cradle includes a pair of apertures located near the bottom and top of the cradle. The dispensing member has a pair of spikes at each end thereof which pass through the pair of apertures in the cradle and pierce the brick pack contained by the cradle. The spikes each have openings therein which communicate with the hollow interior of the dispenser to permit the flow of fluid therein. At the top end of the dispenser is a vent opening having a filter therein for permitting the ingress of air. At the bottom of the dispenser is an opening for permitting the egress of fluid from the brick pack and the dispenser. Preferably the dispenser has a graduated scale to indicate the level of fluid in the brick pack.

Abstract: An implantable medication infusion device (10) includes a pump (34) that provides medication at below atmospheric pressure from a reservoir (32) to a catheter (12) in response to a controller (44). The infusion device (10) includes a septum fitting (14) having a septum (66) and a poppet (84) that is located in a cavity (80) that is in communication with reservoir (32). A fill needle (126) of a passive filling device opens poppet (84) and a vent needle (144) of the filling device is also opened to establish passive flow of medication from a vial (95) into the reservoir (32).

Abstract: A cartridge which discharges a filler such as a bonding agent by pressing directly by a finger or by an exclusive discharger with a plug opening function. A plug member is secured fixedly to the head of a cartridge body, a nozzle is screwed to or engaged with the plug member. The nozzle has a needle or cutting teeth at the bottom, to be deeply screwed or pressed to the plug member to open the plug.

Abstract: A portable machine for carbonating liquid contained in a bottle is adapted to support the bottle (5) by the neck (81) through a bayonet connection and for a seal (64) which closes the bottle neck to be driven into engagement with the bottle neck by a piston (60) actuated by the first burst of gas supplied to the injection nozzle (66). The bottle is loaded into the machine through a front opening (6) and a cover (7) for closing the opening is interlocked with a gas supply valve (12) so that gas can only be delivered to the nozzle (66) when the cover is closed. The cover is opened and closed by rotating a knob (23) which is depressed to open the gas valve. The knob (23) is coupled to the gas valve (12) through a device (27) which prevents the valve being opened if the machine is tilted at more than a given angle to the upright position.