As A Source Of Radiation Or Heat Patents (Class 252/644)
  • Patent number: 10166403
    Abstract: An embodiment of the present disclosure is directed to a brachytherapy source assembly including a guiding wire and a brachytherapy capsule located at a distal end of the guiding wire. The capsule includes a chamber defined by a wall for holding a radioactive source. At least a portion of an exterior surface of the wall of the capsule includes at least one of a friction-reducing coating, a wear-resistant coating, and a wear-indication coating a coating.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: January 1, 2019
    Assignee: Nuvletron Operations B.V.
    Inventors: Pier Bakker, Wim de Jager, Arie Luite Visscher, Henk Vreeken
  • Patent number: 10151018
    Abstract: A method for selectively extracting sedimentogenic strontium and barium from terrigenous elastic sediments to reflect the difference between marine and continental sedimentary environments is disclosed. The method comprises collecting loose sediment, removing visible biogenic clasts, baking the sample and crushing the sample to a grain size no larger than 100-mesh. The method further comprises weighing the sample, reacting the sample in acetic acid or acetic acid-acetate solution, stirring or oscillating the sample at room temperature and normal pressure, separating the solid and liquid after reaction and analyzing strontium and barium in the supernatant. The gained Sr/Ba ratio of the supernatant reflects whether the sediments were deposited in a marine or a continental sedimentary environment.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: December 11, 2018
    Assignee: Nanjing Center of Geological Survey, China Geological Survey
    Inventors: Aihua Wang, Jiankun Liu, Fei Zhang, Hualing Li
  • Patent number: 9011735
    Abstract: Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: April 21, 2015
    Assignee: UT-Battelle, LLC
    Inventors: Wei Wang, Baohua Gu, Scott T. Retterer, Mitchel J. Doktycz
  • Publication number: 20150102238
    Abstract: A glass radiation-source with customized geometries to maximize receipt of radiation into treatment areas that is formed from either neutron-activated glass, radioisotopes molecularly bonded to glass, or radioisotopes encased within glass.
    Type: Application
    Filed: April 2, 2014
    Publication date: April 16, 2015
    Applicant: IP LIBERTY VISION CORPORATION
    Inventors: Paul T. FINGER, Toby WELLES
  • Patent number: 8679377
    Abstract: A gamma radiation source comprises 75Selenium wherein the 75Selenium is provided in the form of compounds, alloys or mixtures with one or more nonmetals which upon irradiation do not produce products capable of sustained emission of radiation which would unacceptably interfere with the gamma radiation of 75Selenium. A further gamma radiation source comprises 75Selenium wherein the 75Selenium is provided in the form of compounds, alloys or mixtures with one or more metals or nonmetals, the neutron irradiation of which does produce products capable of sustained emission of radiation which would acceptably complement the gamma radiation of 75Selenium. Further, the gamma radiation source may have components that are separately irradiated before being combined and the components may be of natural isotopic composition or of isotopically modified composition so that the subsequent radiation peaks may also be adjusted in relative frequency.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: March 25, 2014
    Inventors: John J. Munro, III, Kevin J. Schehr
  • Patent number: 8241532
    Abstract: Neutron source comprising a composite, said composite comprising crystals comprising BeO and AmBe13, and an excess of beryllium, wherein the crystals have an average size of less than 2 microns; the size distribution of the crystals is less than 2 microns; and the beryllium is present in a 7-fold to a 75-fold excess by weight of the amount of AmBe13; and methods of making thereof.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: August 14, 2012
    Assignee: Los Alamos National Security, LLc
    Inventor: Louis D. Schulte
  • Publication number: 20110046701
    Abstract: The present invention provides a composition used for increasing calmodulin and a method thereof. A far-infrared ray is released by a far-infrared releasing substance in the composition so as to induce intracellular calmodulin concentration increased in organisms. The far-infrared releasing substance consists of ceramic minerals and mainly comprises 80-99.9 wt % of oxide minerals including 60-95 wt % of the mineral alumina. The far-infrared releasing substance according to the present invention has the advantages of easy to carry and continuously working, so as to significantly improve the shortcoming of drugs with short-term acting.
    Type: Application
    Filed: September 18, 2009
    Publication date: February 24, 2011
    Applicant: NATIONAL APPLIED RESEARCH LABORATORIES
    Inventors: Yung-Sheng Lin, Ting-Kai Leung, Jiann-Shiun Kao
  • Patent number: 7622532
    Abstract: The present invention relates generally to synthesis of radioactive material, such as a tritiated polymer, and an apparatus for generating electrical current from the nuclear decay process of a radioactive material. In one embodiment, the invention relates to an energy cell (e.g., a battery) for generating electrical current derived from particle emissions occurring within a radioactive material such as a tritiated polymer) on pore walls of a porous semiconductor. The radioactive material may be introduced into the energy cell by a wetting process.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: November 24, 2009
    Assignees: William Marsh Rice University, BetaBatt, Inc.
    Inventors: Larry L. Gadeken, Paul S. Engel, Kenneth S. Laverdure
  • Publication number: 20090173921
    Abstract: The present invention deals with the encapsulation of a nuclear source of energy (Strontium 90) in order to generate up to 600 degree Celsius. The encapsulated Strontium 90 is destined to be used to generate steam, or to liquefy the viscous oil of wells, as well as the paraffin, covering the cables used in the extraction of oil, which makes the extraction difficult or impossible. The encapsulated Strontium 90 has to be transported into a metal housing already patented by Ioan G. Crihan, one of the undersigned authors (FIG. 1).
    Type: Application
    Filed: April 3, 2008
    Publication date: July 9, 2009
    Inventors: Ioan G. Crihan, Geoffrey G. Woods, Jerrold E. Hyams
  • Patent number: 7501077
    Abstract: Composite scintillator material consisting of a binderless sintered mixture of a Lithium (Li) compound containing 6Li as the neutron converter and Y2SiO5:Ce as the scintillation phosphor, and the use of this material as a method for neutron detection. Other embodiments of the invention include various other Li compounds.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: March 10, 2009
    Assignee: UT-Battelle, LLC
    Inventors: Jason P. Hodges, M. Lowell Crow, Jr., Ronald G. Cooper
  • Patent number: 6890457
    Abstract: An adhesive containing a far infrared radiation ceramic powder emitting far infrared rays and a radiation source ceramic powder emitting radiations and anions. The radiation source ceramic powder includes silicon dioxide, aluminum oxide, iron oxide, titanium oxide, calcium oxide, magnesium oxide, potassium oxide, sodium oxide and zirconium and/or radium. The adhesive according to the present invention relaxes human beings, helps spontaneous recovery from diseases and improves health by the synergistic effects of far infrared rays, anions and radiations.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: May 10, 2005
    Inventors: Katsuhiko Umehara, Toshiyuki Waragai
  • Patent number: 6875377
    Abstract: A gamma radiation source comprising selenium-75 or a precursor therefore, wherein the selenium is provided in the form of one or more thermally stable compounds, alloys, or mixed metal phases.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: April 5, 2005
    Assignee: AEA Technology PLC
    Inventor: Mark Golder Shilton
  • Patent number: 6855270
    Abstract: The present invention relates to the use of nanoscintillation systems, or nanoparticles containing fluor molecules, that can be used to detect an electron-emitting or alpha-particle-emitting radioisotope in the absence of organic-solvents commonly used in organic-based liquid scintillation cocktails. The invention also relates to compositions and use of three oil-in-water microemulsion precursors that can be engineered rapidly, reproducibly, and cost-effectively to produce useful nanoparticles less than 100 nanometers.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: February 15, 2005
    Assignee: The University of Kentucky Research Foundation
    Inventors: Russell J. Mumper, Michael Jay
  • Publication number: 20040238802
    Abstract: Preventing incomplete combustion of fuel in a heat apparatus and equipment.
    Type: Application
    Filed: May 12, 2004
    Publication date: December 2, 2004
    Inventor: Tomio Inoue
  • Publication number: 20040178388
    Abstract: The present invention relates to the use of nanoscintillation systems, or nanoparticles containing fluor molecules, that can be used to detect an electron-emitting or alpha-particle-emitting radioisotope in the absence of organic-solvents commonly used in organic-based liquid scintillation cocktails. The invention also relates to compositions and use of three oil-in-water microemulsion precursors that can be engineered rapidly, reproducibly, and cost-effectively to produce useful nanoparticles less than 100 nanometers.
    Type: Application
    Filed: June 6, 2002
    Publication date: September 16, 2004
    Applicant: The University of Kentucky Research Foundation
    Inventors: Russell J. Mumper, Michael Jay
  • Publication number: 20040056240
    Abstract: An adhesive containing a far infrared radiation ceramic powder emitting far infrared rays and a radiation source ceramic powder emitting radiations and anions. The radiation source ceramic powder comprises silicon dioxide, aluminum oxide, iron oxide, titanium oxide, calcium oxide, magnesium oxide, potassium oxide, sodium oxide and zirconium and/or radium. The adhesive according to the present invention relaxes human beings, helps spontaneous recovery from diseases and improves health by the synergistic effects of far infrared rays, anions and radiations.
    Type: Application
    Filed: January 14, 2003
    Publication date: March 25, 2004
    Applicant: Toshiyuki WARAGAI
    Inventors: Katsuhiko Umehara, Toshiyuki Waragai
  • Patent number: 6627908
    Abstract: A radiation source assembly and a connector press used in producing such assemblies. In the radiation source assembly, each of the cap connector and the female connector is provided with internal round threads on its pigtail fitting hole, thus engaging with the large-diameter coil of the pigtail at the internal round threads through a thread engagement prior to a compression process of the press. The assembly also allows a person to know whether both ends of the pigtail fully reach desired points within the two connectors, thus securing a precise compressing target portion during a compression process of the press. The inserted lengths of the pigtail relative to the two connectors are maximize accomplishing a desired linearity of the assembly. In the assembly, a target biasing spring is provided on the capsule lid and allows the disc targets within the source capsule to effectively maintain a desired condition as point sources regardless of the number of targets.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: September 30, 2003
    Assignee: Korea Atomic Energy Research Institute
    Inventors: Hyon Soo Han, Woon Kap Cho, Soon Buk Hong, Kyeong Deuk Jang, Ul Jae Park
  • Patent number: 6489617
    Abstract: Disclosed is a is an improved flood source, and method of making the same, which emits an evenly distributed flow of energy from a gamma emitting radionuclide dispersed throughout the volume of the flood source. The flood source is formed by filling a bottom pan with a mix of epoxy resin with cobalt-57, preferably at 10 to 20 millicuries and then adding a hardener. The pan is secured to a flat, level surface to prevent the pan from warping and to act as a heat sink for removal of heat from the pan during the curing of the resin-hardener mixture.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: December 3, 2002
    Assignee: Battelle Memorial Institute
    Inventors: Darrell R. Fisher, David L. Alexander, Stanley Satz
  • Patent number: 6409943
    Abstract: A radiotheraputical source of Rhenium188 comprises metallic Tungsten188 or a metal oxide of Tungsten188. Therapeutic device using Rhenium188 comprise a radioactive source for the in situ generation of Rhenium188 from Tungsten188.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: June 25, 2002
    Assignee: The State of Israel, Atomic Energy Commission
    Inventors: Efraim Lavie, Daniel Kijel, Eliahu Sayag, Yehoshua Michael Bettan
  • Patent number: 6379648
    Abstract: A nonradioactive glass in particulate form adapted for radiation therapy in a mammal comprise a biodegradable rare earth-lithium borate glass material of a specified composition which, upon being subjected to an effective amount of neutron irradiation, will produce a beta or gamma emitting radioisotope, the radioisotope being distributed throughout the glass material, the glass upon being introduced into a body fluid for radiation therapy being adapted to react therewith causing the radioisotope to form an insoluble compound on the surface of the glass material which is retained in the glass material and thereby prevented from escaping from the treatment site. Radioactive glasses and methods for carrying out radiation therapy with such radioactive glasses are also disclosed.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: April 30, 2002
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, James E. White
  • Patent number: 6235871
    Abstract: The transition metal-catalyzed amination of aryl halides, in conjunction with an orthogonal protective group scheme, forms the basis of two routes to oligoaniline precursors. The oligoaniline precursors are soluble in a variety of common organic solvents, and are easily converted to the deprotected oligoanilines. The method allows the preparation of oligoanilines of even or odd chain lengths, and the incorporation of a variety of functional groups into the oligomers. Polyanilines of low polydispersity can also be prepared by this method.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: May 22, 2001
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert A. Singer, Joseph P. Sadighi, Stephen L. Buchwald, Thomas Mackewitz
  • Patent number: 6221333
    Abstract: A nonradioactive glass in particulate form adapted for radiation therapy in a mammal comprise a biodegradable rare earth-lithium borate glass material of a specified composition which, upon being subjected to an effective amount of neutron irradiation, will produce a beta or gamma emitting radioisotope, the radioisotope being distributed throughout the glass material, the glass upon being introduced into a body fluid for radiation therapy being adapted to react therewith causing the radioisotope to form an insoluble compound on the surface of the glass material which is retained in the glass material and thereby prevented from escaping from the treatment site. Radioactive glasses and methods for carrying out radiation therapy with such radioactive glasses are also disclosed.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: April 24, 2001
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, James E. White
  • Patent number: 5762907
    Abstract: Radiopharmaceutical formulations for complexes comprising at least one radionuclide complexed with a ligand, or its physiologically-acceptable salts thereof, especially .sup.153 samarium-ethylenediaminetetramethylenephosphonic acid, which optionally contains a divalent metal ion, e.g. calcium, and is frozen, thawed, and then administered by injection.
    Type: Grant
    Filed: October 7, 1993
    Date of Patent: June 9, 1998
    Assignee: The Dow Chemical Company
    Inventors: Jaime Simon, Joseph R. Garlich, R. Keith Frank, Kenneth McMillan
  • Patent number: 5494654
    Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabiliser and dye.
    Type: Grant
    Filed: August 23, 1993
    Date of Patent: February 27, 1996
    Assignee: Amersham International plc
    Inventors: Roger M. Price, Christopher C. May, Elizabeth M. Buckley, Timothy Stone
  • Patent number: 5268129
    Abstract: A stabilized radionuclide-colloid composition useful in therapeutic radiation ablation therapies is disclosed. The composition contains a viscosity modifier layered mixed metal hydroxide and optionally an ion exchange medium to stabilize the radioactive colloid.
    Type: Grant
    Filed: May 5, 1992
    Date of Patent: December 7, 1993
    Assignee: The Dow Chemical Company
    Inventors: Jaime Simon, Kenneth McMillan, David A. Wilson, Harrell L. Huff
  • Patent number: 5219556
    Abstract: A method of preparing a stable, therapeutic radiopharmaceutical composition comprised of an alpha- or beta-emitting radionuclide and a ligand by lyophilizing a solution of the complex. The radionuclide preferably has a half-life of at least twelve hours. The invention also is directed to stable lyophilized radiopharmaceutical compositions prepared by this method. The invention is particularly suited to the preparation of radionuclide-labeled antibodies in a stable form which merely requires reconstitution at the point of use.
    Type: Grant
    Filed: July 9, 1990
    Date of Patent: June 15, 1993
    Assignee: Mallinckrodt Medical, Inc.
    Inventor: Robert G. Wolfangel
  • Patent number: 5135735
    Abstract: The invention relates to a method of localizing and quantifying regional energy metabolism, in particular regional ischemia, in a warm-blooded living being, comprising administering to said being a diagonstically effective quantity of a radiolabelled L-homocysteine or a radiolabelled functional derivative thereof. The invention further relates to a pharmaceutical composition to be used for performing the above method.
    Type: Grant
    Filed: December 14, 1990
    Date of Patent: August 4, 1992
    Assignee: Mallinckrodt Medical, Inc.
    Inventor: Jurgen Schrader
  • Patent number: 4938798
    Abstract: A high melting metal silicide sputtering target which comprises a fine texture whose stoichiometric composition grains of MSi.sub.2, where M represents a high melting metal, have a maximum grain size of 20 .mu.m, whose free silicon grains have a maximum grain size of 50 .mu.m and whose oxygen content is not more than 200 ppm and has a density ratio to the theoretical density of 99% or more has good film characteristics including the reduction in the number of grains formed on the sputtered film and is useful as an electrode material or a wiring material in semi-conductor devices.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: July 3, 1990
    Assignee: Hitachi Metals, Ltd.
    Inventors: Yoshitaka Chiba, Noriyoshi Hirao, Toru Sugihara, Kenji Hasegawa
  • Patent number: 4929418
    Abstract: A cathode is made from tungsten powder using as an impregnant the product rmed from adding about 1 mole of a member selected from the group consisting of zirconium, zirconium dioxide, hafnium, hafnium dioxide, uranium, uranium dioxide, titanium, and titanium dioxide to about 50 to about 100 moles of a compound selected from the group consisting of Ba.sub.3 Al.sub.2 O.sub.6, Ba.sub.3 WO.sub.6, and Ba.sub.4 Al.sub.2 O.sub.7.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: May 29, 1990
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Louis E. Branovich, Bernard Smith, Gerard L. Freeman, Eckart Donald W.
  • Patent number: 4891164
    Abstract: A method is disclosed for separating and immobilizing a radioactive material comprising: contacting an aqueous medium containing said radioactive material with a reactive composition comprising at least one alkali metal, at least one Group IIIB metal and at least one phosphorus oxide; maintaining said reactive composition in contact with said aqueous medium for an effective period of time to react a desired amount of said radioactive material with said reactive composition to form a radioactive-material-containing composition; and separating said radioactive-material-containing composition from said aqueous medium. Radioactive-material-containing compositions exhibiting low leach rates are also disclosed.
    Type: Grant
    Filed: January 6, 1989
    Date of Patent: January 2, 1990
    Assignee: The Standard Oil Company
    Inventors: Thomas R. Gaffney, JoAnn Henry, Michael J. Desmond
  • Patent number: 4891165
    Abstract: A capsule for encapsulating radioactive material for radiation treatment comprising two or more interfitting sleeves, wherein each sleeve comprises a closed bottom portion having a circumferential wall extending therefrom, and an open end located opposite the bottom portion. The sleeves are constructed to fit over one another to thereby establish an effectively sealed capsule structure.
    Type: Grant
    Filed: July 28, 1988
    Date of Patent: January 2, 1990
    Assignee: Best Industries, Inc.
    Inventor: Krishnan Suthanthiran
  • Patent number: 4889707
    Abstract: Radioactive microspheres for radiation synovectomy of arithmetic joints in a mammal comprise a biodegradable glass material and a beta radiation emitting radioisotope chemically dissolved in and distributed substantially uniformly throughout the glass material. The biodegradable glass material may be lithium silicate, lithium aluminosilicate, lithium aluminoborate, lithium germanate, lithium aluminogermanate, potassium silicate, potassium aluminosilicate, potassium, aluminoborate, potassium germanate or potassium aluminogermanate and the beta radiation emitting radioisotope may be samarium-153, holmium-166, erbium-169, dysprosium-165, rhenium-186, rhenium-188 or yttrium-90. Methods for preparing such microspheres and for carrying out radiation synovectomy of arthritic joints utilizing such microspheres are also disclosed.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: December 26, 1989
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, Gary J. Ehrhardt
  • Patent number: 4889660
    Abstract: A radioluminescent light source comprises a solid mixture of a phosphorescent substance and a tritiated polymer. The solid mixture forms a solid mass having length, width, and thickness dimensions, and is capable of self-support. In one aspect of the invention, the phosphorescent substance comprises solid phosphor particles supported or surrounded within a solid matix by a tritium containing polymer. The tritium containing polymer comprises a polymer backbone which is essentially void of tritium.
    Type: Grant
    Filed: December 24, 1987
    Date of Patent: December 26, 1989
    Assignee: Battelle Memorial Institute
    Inventors: George A. Jensen, David A. Nelson, Peter M. Molton
  • Patent number: 4861520
    Abstract: A drivable radioactive source capsule is provided which comprises a tubular body containing therein a plurality of radioactive sources. The said tubular body has a first end and a second end which is a terminus of the tubular body. A plug has an elongated closure portion with the diameter of the closure portion being substantially equal to the inside diameter of said tubular body. The closure portion is disposed within the tubular body through the second end thereof and is attached to the second end of the tubular body. The plug has a connection portion adjacent the closure portion with the diameter of the connecting portion being substantially equal to the outside diameter of the tubular body. An elongated flexible drive cable is connected to the connection portion of the plug.
    Type: Grant
    Filed: October 28, 1988
    Date of Patent: August 29, 1989
    Assignee: Eric van't Hooft
    Inventors: Eric van't Hooft, Libbe van Zwol
  • Patent number: 4857234
    Abstract: A partitioning radioactive tracer material is prepared by reacting an alkali-metal salt of radioactive iodine with chloroethanol in the presence of activated carbon.
    Type: Grant
    Filed: March 31, 1988
    Date of Patent: August 15, 1989
    Assignee: Conoco Inc.
    Inventor: Preston L. Gant
  • Patent number: 4834916
    Abstract: Apparatus is disclosed for the dry storage of heat-emitting radioactive waste materials. The latter are stored in tubes placed within a room having at least one cold air inlet and a hot air outlet. The distance between adjacent tubes and the distance between a tube and a wall of the room is such that a conically-shaped hot air boundary layer formed by natural convection around a tube is in contact neither with the boundary layer of another tube, nor with the wall of the room.
    Type: Grant
    Filed: July 14, 1987
    Date of Patent: May 30, 1989
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Luc Chaudon, Michel Dobremelle, Jean-Claude Fabre, Jean Geffroy
  • Patent number: 4827493
    Abstract: A radiography source, preferably a cobalt-60 source constructed of a plurality of radioactive cobalt-60 pellets contained in an open capsule preferably constructed of titanium. The pellets are disposed in the capsule and compacted therein to reduce the source focal size. A plug is disposed in the open capsule and welded therewith. The cobalt and titanium materials are sufficiently different in atomic number to permit good X-ray analysis resolution.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: May 2, 1989
    Assignee: Amersham Corporation
    Inventors: George W. Parsons, Robert L. Kelly, Joseph M. Zlotnicki
  • Patent number: 4826961
    Abstract: A method for preparing radiopharmaceutical complexes that are substantially free of the reaction materials used to produce the radiopharmaceutical complex is disclosed. The method involves admixing in a suitable first solvent in a container a target seeking ligand or salt or metal adduct thereof, a radionuclide label, and a reducing agent for said radionuclide, thereby forming said radiopharmaceutical complex; coating the interior walls of the container with said pharmaceutical complex; discarding the solvent containing by-products and unreacted starting reaction materials; and removing the radiopharmaceutical complex from said walls by dissolving it in a second solvent, thereby obtaining said radiopharmaceutical complex substantially free of by-products and unreacted starting materials.
    Type: Grant
    Filed: January 22, 1987
    Date of Patent: May 2, 1989
    Assignees: President and Fellows of Harvard College, Massachusetts Institute of Technology
    Inventors: Alun G. Jones, Alan Davison, Michael J. Abrams
  • Patent number: 4789501
    Abstract: A radioactive microsphere for radiation therapy of a mammal comprising a biologically compatible glass material containing a beta or gamma emitting radioisotope distributed substantially uniformly throughout the glass. Advantageously, the radioisotope is produced by irradiation of the microsphere.
    Type: Grant
    Filed: November 19, 1984
    Date of Patent: December 6, 1988
    Assignee: The Curators of the University of Missouri
    Inventors: Delbert E. Day, Gary J. Ehrhardt
  • Patent number: 4707322
    Abstract: Beryllium-7 labeled carbon particles made from the proton irradiation of carbon materials, preferably from dry carbon black are disclosed. Such particles are useful as gamma emitting radiotracers.
    Type: Grant
    Filed: April 29, 1985
    Date of Patent: November 17, 1987
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Powell Richards, Leonard F. Mausner, Thomas F. Prach
  • Patent number: 4430258
    Abstract: Method of producing liquid equivalent solid gamma ray calibration standards comprising the steps of adding a first organic solvent to a calibrated aqueous solution of radioactive material, either in the form of a single isotope or mixed isotopes, to form a first solution; mixing the first solution with a polymerizible resin dissolved in a second organic solvent together with a hardening catalyst to form a second solution; and curing the second solution. With isotope standards requiring highly acidic conditions, a stabilizing agent is added to the first solvent to complex with metal and hydrogen ions so as to prevent plate-out.
    Type: Grant
    Filed: May 28, 1981
    Date of Patent: February 7, 1984
    Inventors: Robert C. McFarland, Patricia A. McFarland
  • Patent number: 4411881
    Abstract: A stabilized composition comprising a solution of a radiolabeled compound and a diethylenetriamine is described. Preferred diethylenetriamines include, N,N-bis(2-aminoethyl) dithiocarbamic acid, di(2-dithiocarbamyl-ethyl) amine, and salts thereof.
    Type: Grant
    Filed: July 12, 1982
    Date of Patent: October 25, 1983
    Assignee: New England Nuclear Corporation
    Inventor: Nathan R. Tzodikov
  • Patent number: 4406697
    Abstract: A radioactive .sup.57 Co source consists of the intermetallic composition CoSb.sub.3 which emits an energetically non-disintegrated 14.4 KeV line. This composition is strictly stoichiometrical and may be dissolved in excess Sb. The atom percent proportion of .sup.57 Co may be up to 25%.
    Type: Grant
    Filed: January 21, 1981
    Date of Patent: September 27, 1983
    Assignees: Fritz Parak, Jorg Loock
    Inventors: Fritz Parak, Jorg Loock, Runar Kouzmine
  • Patent number: 4362659
    Abstract: This invention relates to radioactive materials which are fixed, stored, entrapped, encapsulated, or otherwise rendered immobile in a glass matrix for extremely long periods of time. Radioactive material such as radioactive wastes are incorporated into a glass matrix by a process of "molecular stuffing" a porous glass either with a radioactive gas which is tapered in the porous glass by dissolution during sintering of the pores of the glass, or with a salt solution containing radioactive material such as CsNO.sub.3, Sr(NO.sub.3), etc., or with a combination of both salt solution and radioactive gas, followed by drying and sintering of the pores of the glass whereby these radioactive materials upon chemical change to their oxides, excepting of course the noble gases which remain in molecular form, become a part of the integrated glass structure.
    Type: Grant
    Filed: September 17, 1979
    Date of Patent: December 7, 1982
    Assignees: Pedro B. Macedo, Theodore A. Litovitz
    Inventors: Pedro B. Macedo, Joseph H. Simmons, Theodore A. Litovitz