Abstract: Provided are a SiC/ZrC composite fiber, a preparation method and use thereof. The SiC/ZrC composite fiber has a diameter of 10 to 70 ?m. The method includes mixing liquid polycarbosilane with a zirconium-containing polymer to obtain a hybrid spinning solution, and then performing electrospinning to obtain a SiC/ZrC composite fiber precursor, crosslinking and thermally treating the SiC/ZrC composite fiber precursor in a protective atmosphere to obtain the SiC/ZrC composite fiber. The SiC/ZrC composite fiber is continuous and uniform, has an adjustable diameter, and thus has outstanding tensile strength and breaking strength and excellent high-temperature resistance. Without use of any organic solvent or spinning agent, the method achieves short process flow and high yield, indicating wide application prospects.

Abstract: A carbon nanocomposite includes a polymer nanowire comprising a plurality of carbon nanostructures, wherein the plurality of carbon nanostructures are electrically connected to each other within the polymer nanowire, and a portion of the plurality of carbon nanostructures protrude from a surface of the polymer nanowire.

Abstract: A fluidic probe comprising a plurality of oriented fibers with individual fibers having nano-pores in the fiber bodies, the oriented fibers being twisted together, wherein the twisted oriented fibers form micro-pores between the individual fibers, is disclosed. The fluidic probe exhibits excellent flexibility, deployability and absorptive capacity. The enhanced absorptive capacity is due to the fluid absorption via capillary action of the nano-pores and fluid transport via the micro-pores. The probes can also be formed so as to be remotely controlled by electromagnetic fields and thus be used in a hands-free fashion. With these probes, the paradigm of a stationary microfluidic platform can be shifted to include flexible structures that can include multiple microfluidic sensors in a single fibrous probe.

Abstract: Provided herein are nanofibers comprising carbon precursors, nanofibers comprising carbon matrices, and processes for preparing the same. In specific examples, provided herein are high performance lithium ion battery anodic nanofibers comprising non-aggregated silicon domains in a continuous carbon matrix.

Abstract: An ultrafine fiber comprises a ceramic-based fibrous body and a biologically active substance encapsulated in the body, substantially encapsulated in the body, or surface-attached to the body. In an example, an ultrafine fiber comprises a core comprising a biologically active substance and a ceramic-based shell surrounding or substantially surrounding the core.

Abstract: A method of fabricating a thermoplastic component using inductive heating is described. The method includes positioning a plurality of induction heating coils to define a process area for the thermoplastic component, wherein the plurality of induction heating coils comprises a first set of coils and a second set of coils. The method also includes controlling a supply of electricity provided to the plurality of inductive heating coils to intermittently activate the coils. The intermittent activation is configured to facilitate prevention of electromagnetic interference between adjacent coils.

Abstract: A system for kneading and extruding a material includes a crusher for crushing the material into coarse particles, an extruder for conveying and extruding the material crushed by the crusher, a gear pump for receiving and discharging the material extruded from the extruder, and a kneading and extruding apparatus for kneading the material discharged from the gear pump and continuously extruding the kneaded material. Therefore, a material is accurately quantified and highly uniform, resulting in reduced product variations and ensured consistent quality.

Abstract: High glass transition temperature lignin derivatives and methods of making the same are disclosed herein. In addition, methods for making carbon nanofibers from the lignin derivatives is also provided. The lignin derivatives disclosed herein are suitable for electrospinning and provide increased efficiency in production of carbon nanofibers. The lignin derivatives may be obtained using the methods disclosed herein from pulping processes conducted on lignin stock material.

Abstract: Upon producing a meta-type wholly aromatic polyamide fiber by wet spinning a polymer solution containing a meta-type wholly aromatic polyamide containing a m-phenylenediamine isophthalamide skeleton as a major component, and an amide solvent containing a salt, (1) the polymer solution is ejected into a coagulation bath containing an amide solvent and water and containing a salt at a low concentration to coagulate as a porous thread body (fibrous material), (2) which is subsequently stretched in a plastic stretching bath containing an aqueous solution of an amide solvent, (3) is rinsed with water and then subjected to a heat treatment in a saturated steam atmosphere, and (4) is then subjected to a dry heat treatment, so as to produce a novel meta-type wholly aromatic polyamide fiber that contains an extremely small amount of a solvent remaining in the fibers, contains a small amount of a volatile substance harmful in a heat treatment step at a high temperature, is capable of suppressing coloration of a fiber p

Abstract: The invention relates to a ceramic particle mixture containing, as components, a predominant portion by weight of frittable particles made of a ceramic material and particles of at least one additive, at least one additive being a dispersed absorbent solid inorganic material which has, for a laser beam emitted at a predetermined wavelength, a specific absorptivity that is greater than the absorptivity of the other components of the ceramic mixture, and which drastically breaks down when gas is emitted in the presence of the laser beam, said additive being present in proportions of less than 5% of the dry weight. The invention also relates to ceramic parts produced from such a mixture.

Abstract: A process for manufacturing silver nanowires is provided, comprising: providing a silver ink core component containing ?60 wt % silver nanoparticles dispersed in a silver carrier; providing a shell component containing a film forming polymer dispersed in a shell carrier; providing a substrate; coelectrospinning the silver ink core component and the shell component depositing on the substrate a core shell fiber having a core and a shell surrounding the core, wherein the silver nanoparticles are in the core; and, treating the silver nanoparticles to form a population of silver nanowires, wherein the population of silver nanowires exhibit an average length, L, of ?60 ?m.

Abstract: A process of manufacturing inorganic nanofibers, without using an organic polymer, using a highly reactive metal alkoxide such as titanium alkoxide or zirconium alkoxide, in particular, a process in which inorganic nanofibers can be stably produced over a long period, is provided. It is a process of manufacturing inorganic nanofibers by electrospinning using a sol solution containing an inorganic component as a main component, characterized in that the sol solution contains a metal alkoxide having a high reactivity and a salt catalyst, and that the salt catalyst is an amine compound having an N—N bond, an N—O bond, an N—C?N bond, or an N—C?S bond.

Abstract: Embodiments of the present disclosure provide electrospinning devices, methods of use, uncompressed fibrous mesh, and the like, are disclosed.

Abstract: The invention relates to a hydraulic binder product [12, 10] which includes a mixture of a hydraulic binder [38, 202], a polyvinyl alcohol [14, 204] and a gelling agent [54] which reacts with the polyvinyl alcohol and a method [8] of producing same.

Abstract: The present invention provides a method for manufacturing a film for a film capacitor making it possible to produce a film for a film capacitor which has a thickness of 10 ?m or less and which is excellent in a heat resistance and a voltage resistance at a high thickness accuracy by using a polyetherimide resin and provides as well a film for a film capacitor.

Abstract: The present invention pertains to a process for producing unmeltable polysilane-polycarbosilane copolymers which are soluble in inert solvents, comprising the steps providing the product of a disproportionation of a methylchlorodisilane or a mixture of several methylchlorodisilanes of the composition Si2MenCl6-n, wherein n=1?4, wherein the disproportionation was carried out with a Lewis base as a catalyst, wherein this product is a chlorine-containing, crude polysilane/oligosilane containing hydrocarbon groups, and thermally postcrosslinking the crude polysilane/oligosilane to a polysilane-polycarbosilane copolymer, characterized in that the chlorine content of the polysilane-polycarbosilane copolymer is lowered by reacting the crude polysilane/oligosilane with a substitution agent, by which chlorine bound therein is replaced with a chlorine-free substituent. Green fibers and low-oxygen/oxygen-free ceramic fibers with a very low chlorine content can be produced using this process.

Abstract: Methods for controlled electrospinning of polymer fibers are described. The methods include spinning a polymer fiber from a fluid comprising a polymer in the presence of an electric field established between a plurality of collectors and a jet supply device controlling the dispersion characteristics of the fluid by applying a magnetic field created by at least one magnet located after the point of jet formation. Different voltages are applied to at least two collectors of the plurality of collectors. At least one magnet, located between the jet supply device and at least one collector, creates a magnetic field substantially transverse or substantially collinear to an electrospinning jet stream. The magnetic field changes direction of travel of the electrospinning jet stream.

Abstract: Exemplary embodiments provide core-sheath nanofibers produced by coaxial electrospinning, fuser members comprising core-sheath nanofibers, and methods for forming core-sheath nanofibers that can include a core solution comprising a high performance polymer and sheath solutions comprising a solvent-soluble fluoropolymer or solvent-insoluble fluororesins and a sacrificial polymeric binder.

Abstract: The present invention relates to an improved insulation fiber material on the basis of mineral wool, as well as to a method for producing said improved insulation material.

Abstract: Various methods and systems are provided for the fabrication of patterned nanofibers. In one embodiment, a method includes generating a layer of electrospun nanofibers from a polymer solution and patterning the layer of electrospun nanofibers using ultraviolet (UV) lithography. The patterned electrospun nanofibers may then be thermally treated to form patterned carbon nanofibers. In another embodiment, a device includes a layer of patterned carbon nanofibers formed by generating electrospun nanofibers from a polymer solution, patterning the electrospun nanofibers using UV lithography, and converting the patterned electrospun nanofibers into patterned carbon nanofibers using a thermal treatment.

Abstract: An inorganic fiber structure comprising inorganic nanofibers having an average fiber diameter of 3 ?m or less, in which an entirety including the inside thereof is adhered with an inorganic adhesive, and the porosity thereof is 90% or more, is disclosed.

Abstract: A plasticized ceramic-forming mixture and a method for stiffening the mixture, the mixture comprising a combination of inorganic powder, one or more plasticizing organic binders, a radiation-curable monomer, a photoinitiator, and water, and the method comprising stiffening the surfaces of extruded shapes of the mixture by applying electromagnetic energy to the surfaces following extrusion.

Abstract: The present invention provides a process for manufacturing a carbon nanofiber comprising: (a) mixing a carbon nanofiber precursor and camphor in a solvent to prepare a solution; (b) electric spinning the solution to obtain a nanofiber; (c) oxidative stabilizing the nanofiber; and (d) carbonizing the oxidative stabilized nanofiber, wherein camphor is volatilized to form micropores in the oxidative stabilization and carbonization. The present invention also provides a carbon nanofiber manufactured by the same.

Abstract: A process of manufacturing inorganic nanofibers, without using an organic polymer, using a highly reactive metal alkoxide such as titanium alkoxide or zirconium alkoxide, in particular, a process in which inorganic nanofibers can be stably produced over a long period, is provided. It is a process of manufacturing inorganic nanofibers by electrospinning using a sol solution containing an inorganic component as a main component, characterized in that the sol solution contains a metal alkoxide having a high reactivity and a salt catalyst, and that the salt catalyst is an amine compound having an N—N bond, an N—O bond, an N—C?N bond, or an N—C?S bond.

Abstract: A microwave applicator assembly includes a microwave applicator that excites TE modes and provides a generally circular heating pattern in a lossy dielectric material. The microwave applicator has a processing chamber bounded by a circumferential wall in which a plurality of indents are formed. The microwave applicator assembly may further include a feed waveguide coupled to the microwave applicator for inputting microwaves into the processing chamber. The microwave applicator assembly may further include one or more choking sections in communication with the processing chamber to enhance heating efficiency and reduce microwave leakage.

Abstract: Single crystal MoO3 nanowires were produced using an electrospinning technique. High resolution transmission electron microscopy (HRTEM) revealed that the 1-D nanostructures are from 10-20 nm in diameter, on the order of 1-2 ?m in length, and have the orthorhombic MoO3 structure. The structure, crystallinity, and sensoric character of these electrostatically processed nanowires are discussed. It has been demonstrated that the non-woven-network of MoO3 nanowires exhibits higher sensitivity and an n-type response to NH3 as compared to the response of a sol-gel based sensor.

Abstract: A method and apparatus for making a metallic nanofiber structure are disclosed. The method includes the steps of: providing a first solution including a first material and a second material, wherein the second material includes at least one metal; forming the first solution into composite fibers including the first material and the second material; and removing the first material from the composite fibers under conditions effective to produce a metallic nanofiber structure that includes a plurality of metallic nanofibers. Also disclosed are metallic nanofiber structures prepared according to a process of the present invention, which can be used as fuel cell catalysts. Fuel cells containing electrodes that include these metallic nanofiber structures are also disclosed.

Abstract: Device and method for preparing filament yarn of composite nanofibers. The device includes pairs of electrospinning nozzles on a frame and filament guiding roller pair under the frame. The spouts of each pair of nozzles are oppositely facing. The method includes feeding polymer solutions to the pairs of nozzles, applying high DC voltage with opposite polarity respectively to each one of the pairs of nozzles, forming composite nanofibers by attracting nanofibers with opposite charge from each nozzle and striking together of the charged nanofibers, pulling/stretching the composite nanofibers to form filament yarn of composite nanofibers, drawing down the filament yarn of composite nanofibers from the first pair of nozzles and using it as a carrier to receive the nanofibers with opposite charge electrospun from the second pair of nozzles and coated by the same so as to form multi-layer (e.g., two- or more-layer) filament yarn of composite nanofibers.

Abstract: The present invention relates to the fields of chemistry and biology and more particularly to the field of biomaterials. The present invention includes amphiphilic fibers and membranes, which can be used for biomembranes and biocompatible devices. The present invention also relates to processes for preparing amphiphilic fibers and membranes from solutions comprising amphiphilic molecules. More particularly, the present invention relates to processes for preparing fibers and membranes from electrospinning solutions comprising amphiphilic molecules. The present invention further provides fibers and nonwoven membranes comprising amphiphilic fibers chosen from anionic surfactants, cationic surfactants, nonionic surfactants, phospholipids, sulfobetaines, lyotropic liquid crystalline molecules, and/or block copolymers.

Abstract: Multiple solid materials are introduced to a mixing vessel in defined proportion. They are melted by an electromagnetic induction heated susceptor and mixed simultaneously by the shearing action at the melt face of a second rotating susceptor. Material compounding takes place at the application site. Varying the physical structure of the susceptor or multiple susceptors processes materials of differing initial melt viscosity and particle size. Non-melting particulate material can be included in the mix. Reactive components can be combined at the application site.

Abstract: A process for manufacturing an inorganic material-based article comprising the steps of (1) forming a sol solution mainly composed of an inorganic component, (2) producing inorganic material-based gel fine fibers by extruding the resulting sol solution from a nozzle, and at the same time, applying an electrical field to the extruded sol solution to thin the extruded sol solution, and then, collecting inorganic material-based gel fine fibers on a support, (3) drying the collected inorganic material-based gel fine fibers to produce inorganic material-based article containing inorganic material-based dried gel fine fibers, and then, (4) sintering the inorganic material-based article containing inorganic material-based dried gel fine fibers to produce inorganic material-based article containing inorganic material-based sintered fine fibers.

Abstract: This invention concerns a process for coating a substrate, and an extrusion coatig structure. According to the present process, the coating is provided by producing a bimodal polyethylene composition by subjecting ethylene, optionally with hydrogen and/or comonomers to polymerization or copolymerization reactions in a multistage polymerization sequence of successive polymerization stages. The polymerization reactions are carried out in the presence of a single site catalyst capable of forming a composition which comprises a low molecular weight component with an MFR2 of 20 g/10 min or more and a density higher than the density of the composition, and a high molecular weight component, said composition having a melt flow rate MFR2 of 5 g/10 min or more and a density of 915-960 kg/m3. The composition is extruded on the substrate as such or by adding 10 wt-% or less, calculated from the total weight of the coating, of high pressure PE-LD by blending into the extrusion composition or by coextrusion.

Abstract: The present invention provides a microencapsulation method of a solid substance and the microencapsulated composition obtained from said method of: (i) preparing a dispersion phase comprising (a) a solution containing a substance which forms a middle layer and (b) a solid substance that is insoluble or difficult to dissolve in said solution, (ii) obtaining a solid substance which has a layer made of the substance which forms the middle layer by phase-separating the substance which forms the middle layer from the solution and (iii) reacting a monomer that is polymelizable by condensation in the presence of the solid substance that has a layer made of the substance which forms the middle layer.The above method can efficiently microencapsulate pharmaceutical active ingredients, pesticidal ingredients, aroma active ingredient and so on that are solid substances and affords an efficacious microencapsulated composition of solid substances.

Abstract: Described are an injectable formulation of nanoparticulate naproxen that produces minimal or no pain or burning sensation upon administration, and methods of making and using such a formulation. The injectable formulation comprises nanoparticulate naproxen having a povidone polymer adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 600 nm.

Abstract: A preparation method for biodegradable polymeric microspheres using a solvent extraction method for biodegradable polymeric microspheres for treating a local inflammation disease using the same which are capable of effectively curing ozena such as sinusitis and a middle ear infection. Since a non-solvent of polymer is added into an outer aqueous phase in advance, the solidification of the polymer is implemented in a short time which, in turn, improves encapsulation of the therapeutic agent used.

Abstract: A microcapsule includes a shape memory resin shell wall formed with fissures that do not completely pass through the shell wall, and a dye encapsulated in the shell wall. The shell wall exhibits a temperature/pressure characteristic such that the fissures open, when the shell wall is squashed and compacted under a predetermined pressure at a predetermined temperature, whereby a seepage of the dye frog the squashed and compacted shell wall through the opened fissures is adjustable.

Abstract: High concentration drag reducing agents may be prepared by microencapsulating polymer drag reducing agent. The microencapsulation may be performed prior to, during, or after the polymerization of monomer into effective drag reducing polymer. If encapsulation is done before or during polymerization, a catalyst may be present, but little or no solvent is required. The result is very small scale bulk polymerization within the microcapsule. The inert capsule or shell may be removed before, during or after introduction of the microencapsulated drag reducer into a flowing liquid. No injection probes or other special equipment is expected to be required to introduce the drag reducing slurry into the liquid stream, nor is grinding (cryogenic otherwise) of the polymer necessary to form a suitable drag reducing agent.

Abstract: This invention relates to the process for the preparation of polyurethane with controlled particle size and shape. More, particularly it relates to the production of polyurethane microspheres from a diol and diisocyanate by dispersion polymerization in presence of a steric stabilizer and a catalyst in an organic solvent at a controlled temperature, and finally separating the spherical polyurethane particles from the reaction mixture by conventional means.

Abstract: Disclosed herein are novel electrophoretic displays and materials useful in fabricating such displays. In particular, novel encapsulated displays are disclosed. Particles encapsulated therein are dispersed within a suspending, or electrophoretic, fluid. This fluid may be a mixture of two or more fluids or may be a single fluid. The displays may further comprise particles dispersed in a suspending fluid, wherein the particles contain a liquid. In either case, the suspending fluid may have a density or refractive index substantially matched to that of the particles dispersed therein. Finally, also disclosed herein are electro-osmotic displays. These displays comprise at least one capsule containing either a cellulosic or gel-like internal phase and a liquid phase, or containing two or more immiscible fluids. Application of electric fields to any of the electrophoretic displays described herein affects an optical property of the display.

Abstract: A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymer, an active agent, and a solvent. An immiscible second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The two phases are immersed in a quench liquid that includes a quench medium and a quantity of the solvent. The quantity of the solvent is selected to control a rate of extraction of the solvent from the first phase. The first phase is isolated in the form of microparticles. Also disclosed is a microencapsulated active agent prepared by the method for preparing biodegradable, biocompatible microparticles.

Abstract: Provided are microcapsules enclosing therein a magnetic fluid, which are useful for imparting sound-absorbing and insulating ability to building materials, etc. by incorporation thereinto or adhesion thereto by means of an adhesive, and processes for producing the microcapsules. The heat-expandable microcapsule of the present invention comprises (i) a shell composed of a thermoplastic resin and (ii) a magnetic fluid which is a dispersion of magnetic substance fine particles having an average particle diameter of 5-200 nm in a hydrophobic organic solvent and a hydrophobic liquid foaming agent, both enclosed in the shell. The hollow microcapsule of the present invention comprises (i) a shell composed of a thermoplastic resin, and (ii) a magnetic fluid which is a dispersion of magnetic substance fine particles having an average particle diameter of 5-200 nm in a hydrophobic organic solvent and a vacant cell both included in the shell.

Abstract: The invention relates to accurately meterable shaped articles, for example granules or pellets, containing hydrophilic macromolecules, active compounds and optionally further pharmaceutically acceptable structure-forming substances and auxiliaries, the active compound being present in a matrix in dissolved, suspended or emulsified form, and a novel process for the production of these shaped articles, the process being particularly economically and ecologically acceptable, and use of the shaped articles as medicaments, in which the bioavailability, shelf life and tolerability is increased. Using the shaped articles or mixtures according to the invention, intermediates or final products for pharmacy, cosmetics, diagnosis, analysis or dietetics (healthcare) can additionally be advantageously prepared.

Abstract: A process for producing a microencapsulated system comprising the steps of: (a) emulsifying a solution of color precursor in a solvent as a first internal phase and a diluent as a second internal phase in an external phase to produce discrete droplets of each of said first and second phases; and (b) encapsulating said droplets, is disclosed. A recording sheet is also disclosed which comprises a substrate having a layer of microencapsules containing a color precursor solution and microcapsules containing a diluent. Preferably the microcapsules are clusters of gelatin capsules.

Abstract: Methods are provided for forming spherical multilamellar microcapsules having alternating hydrophilic and hydrophobic liquid layers, surrounded by flexible, semi-permeable hydrophobic or hydrophilic outer membranes which can be tailored specifically to control the diffusion rate. The methods of the invention rely on low shear mixing and liquid-liquid diffusion process and are particularly well suited for forming microcapsules containing both hydrophilic and hydrophobic drugs. These methods can be carried out in the absence of gravity and do not rely on density-driven phase separation, mechanical mixing or solvent evaporation phases. The methods include the process of forming, washing and filtering microcapsules. In addition, the methods contemplate coating microcapsules with ancillary coatings using an electrostatic field and free fluid electrophoresis of the microcapsules. The microcapsules produced by such methods are particularly useful in the delivery of pharmaceutical compositions.

Abstract: Disclosed are microcapsules comprising a polymer shell enclosing two or more immiscible liquid phases in which a drug, or a prodrug and a drug activator are partitioned into separate phases, or prevented from diffusing out of the microcapsule by a liquid phase in which the drug is poorly soluble. Also disclosed are methods of using the microcapsules for in situ activation of drugs, where upon exposure to an appropriate energy source the internal phases mix and the drug is activated in situ.

Abstract: A composition for the sequestration and sustained delivery of an active ingredient in the form of porous particles, the composition comprising the product of the controlled dehydration of particles formed by the reaction of a polymeric anionic material with a polyvalent cation. The composition may be loaded with an active ingredient by soaking the particles in a solution of the active ingredient; and may then be dehydrated. They may then be soaked in a solution of a polymeric cationic material, to form particles providing the controlled release of the active ingredient.

Abstract: This invention provides a heterotelechelic oligomer or polymer which is represented by the following formula: ##STR1## wherein A denotes a sugar residue, L denotes a linkage group represented by the following formula ##STR2## wherein R.sup.1 and R.sup.2 independently denote lower alkyl, aralkyl or aryl,X denotes a single bond or --CH.sub.2 CH.sub.2 --, Z denotes a group forming an unsaturated ester or ether, or a functional group such as halogen which binds to --CH.sub.2 CH.sub.2 --, n denotes an integer of 5-10,000, and m denotes an integer of 0 or 2-10,000.This invention also provides a process to produce the above oligomer or polymer, and further a high molecular-micelle with use of a polyethylene oxide-polyester block polymer which has a sugar residue at its terminal. Said oligomer or polymer is expected to exhibit excellent bioavailability, and is also expected to be utilized in the field such as carriers for drug delivery or diagnostic reagents.

Abstract: The present invention is directed to an implantable, slow-release, self-absorbing, biologically compatible drug delivery system such as slow-release pharmaceutical compositions, including for example, slow-release, allergy desensitization compositions containing one or more allergens in combination with a biologically-compatible, self-absorbing matrix. The present system is useful for treating disorders including, for example, infections, deficiencies or allergies. The present invention is also directed to methods of treating a patient suffering from a disorder, as well as methods for desensitizing a patient to one or more allergens. The present invention also relates to a device for implanting the present composition in a patient.

Abstract: A process and installation are provided for making an extruded sintered ceramic product. The method involves extruding a moist profile and simultaneously drying it with microwave radiation as it is extruded. As the profile is extruded and dried, it is supported at a position where it has been at least partially dried. The installation comprises extrusion means for extruding a moist profile, support means for supporting the extruded profile at an at least partially dried part thereof, and a microwave radiation source for directing microwaves at the profile.

Abstract: A controlled release delivery system includes a functional gene vector in a biodegradable polymeric microsphere encapsulating the vector. The present invention further provides a method of making a controlled release delivery system by encapsulating the functional gene vector in a biologically degradable polymeric microsphere.