Including Extruding (e.g., Spinning, Etc.) Patents (Class 264/433)
  • Patent number: 9383292
    Abstract: A fluidic probe comprising a plurality of oriented fibers with individual fibers having nano-pores in the fiber bodies, the oriented fibers being twisted together, wherein the twisted oriented fibers form micro-pores between the individual fibers, is disclosed. The fluidic probe exhibits excellent flexibility, deployability and absorptive capacity. The enhanced absorptive capacity is due to the fluid absorption via capillary action of the nano-pores and fluid transport via the micro-pores. The probes can also be formed so as to be remotely controlled by electromagnetic fields and thus be used in a hands-free fashion. With these probes, the paradigm of a stationary microfluidic platform can be shifted to include flexible structures that can include multiple microfluidic sensors in a single fibrous probe.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: July 5, 2016
    Assignee: CLEMSON UNIVERSITY
    Inventors: Konstantin G. Kornev, Chen-Chih Tsai, David Lukas, Petr Mikes
  • Publication number: 20150076742
    Abstract: Provided herein are nanofibers comprising carbon precursors, nanofibers comprising carbon matrices, and processes for preparing the same. In specific examples, provided herein are high performance lithium ion battery anodic nanofibers comprising non-aggregated silicon domains in a continuous carbon matrix.
    Type: Application
    Filed: August 12, 2014
    Publication date: March 19, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: Yong Lak Joo, Kyoung Woo Kim, Yong Seok Kim
  • Publication number: 20140335148
    Abstract: An ultrafine fiber comprises a ceramic-based fibrous body and a biologically active substance encapsulated in the body, substantially encapsulated in the body, or surface-attached to the body. In an example, an ultrafine fiber comprises a core comprising a biologically active substance and a ceramic-based shell surrounding or substantially surrounding the core.
    Type: Application
    Filed: May 7, 2014
    Publication date: November 13, 2014
    Inventors: Ho-Wang Tong, Lawrence P. Wackett, Alptekin Aksan
  • Patent number: 8884201
    Abstract: A method of fabricating a thermoplastic component using inductive heating is described. The method includes positioning a plurality of induction heating coils to define a process area for the thermoplastic component, wherein the plurality of induction heating coils comprises a first set of coils and a second set of coils. The method also includes controlling a supply of electricity provided to the plurality of inductive heating coils to intermittently activate the coils. The intermittent activation is configured to facilitate prevention of electromagnetic interference between adjacent coils.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: November 11, 2014
    Assignee: The Boeing Company
    Inventors: Marc R. Matsen, Mark A. Negley
  • Patent number: 8876511
    Abstract: A system for kneading and extruding a material includes a crusher for crushing the material into coarse particles, an extruder for conveying and extruding the material crushed by the crusher, a gear pump for receiving and discharging the material extruded from the extruder, and a kneading and extruding apparatus for kneading the material discharged from the gear pump and continuously extruding the kneaded material. Therefore, a material is accurately quantified and highly uniform, resulting in reduced product variations and ensured consistent quality.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: November 4, 2014
    Assignee: Kobe Steel, Ltd.
    Inventors: Yasuaki Yamane, Hideo Funahashi, Koichi Miyake
  • Publication number: 20140271443
    Abstract: High glass transition temperature lignin derivatives and methods of making the same are disclosed herein. In addition, methods for making carbon nanofibers from the lignin derivatives is also provided. The lignin derivatives disclosed herein are suitable for electrospinning and provide increased efficiency in production of carbon nanofibers. The lignin derivatives may be obtained using the methods disclosed herein from pulping processes conducted on lignin stock material.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Inventors: Darren A. Baker, Omid Hosseinaei
  • Patent number: 8802233
    Abstract: Upon producing a meta-type wholly aromatic polyamide fiber by wet spinning a polymer solution containing a meta-type wholly aromatic polyamide containing a m-phenylenediamine isophthalamide skeleton as a major component, and an amide solvent containing a salt, (1) the polymer solution is ejected into a coagulation bath containing an amide solvent and water and containing a salt at a low concentration to coagulate as a porous thread body (fibrous material), (2) which is subsequently stretched in a plastic stretching bath containing an aqueous solution of an amide solvent, (3) is rinsed with water and then subjected to a heat treatment in a saturated steam atmosphere, and (4) is then subjected to a dry heat treatment, so as to produce a novel meta-type wholly aromatic polyamide fiber that contains an extremely small amount of a solvent remaining in the fibers, contains a small amount of a volatile substance harmful in a heat treatment step at a high temperature, is capable of suppressing coloration of a fiber p
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: August 12, 2014
    Assignee: Teijin Limited
    Inventors: Kotaro Takiue, Hiroshi Fujita
  • Publication number: 20140179511
    Abstract: The invention relates to a ceramic particle mixture containing, as components, a predominant portion by weight of frittable particles made of a ceramic material and particles of at least one additive, at least one additive being a dispersed absorbent solid inorganic material which has, for a laser beam emitted at a predetermined wavelength, a specific absorptivity that is greater than the absorptivity of the other components of the ceramic mixture, and which drastically breaks down when gas is emitted in the presence of the laser beam, said additive being present in proportions of less than 5% of the dry weight. The invention also relates to ceramic parts produced from such a mixture.
    Type: Application
    Filed: May 31, 2012
    Publication date: June 26, 2014
    Applicant: CENTRE DE RECHERCHE DE L'INDUSTRIE BELGE LA CÉRAMIQUE
    Inventors: Fabrice Petit, Veronique Lardot, Cedric Ott, Enrique Juste, Francis Cambier
  • Publication number: 20140027954
    Abstract: A process for manufacturing silver nanowires is provided, comprising: providing a silver ink core component containing ?60 wt % silver nanoparticles dispersed in a silver carrier; providing a shell component containing a film forming polymer dispersed in a shell carrier; providing a substrate; coelectrospinning the silver ink core component and the shell component depositing on the substrate a core shell fiber having a core and a shell surrounding the core, wherein the silver nanoparticles are in the core; and, treating the silver nanoparticles to form a population of silver nanowires, wherein the population of silver nanowires exhibit an average length, L, of ?60 ?m.
    Type: Application
    Filed: July 22, 2013
    Publication date: January 30, 2014
    Applicant: Rohm and Haas Electronic Materials LLC
    Inventors: Jerome Claracq, Garo Khanarian, Lujia Bu, Jaebum Joo, Peter Trefonas
  • Patent number: 8562895
    Abstract: A process of manufacturing inorganic nanofibers, without using an organic polymer, using a highly reactive metal alkoxide such as titanium alkoxide or zirconium alkoxide, in particular, a process in which inorganic nanofibers can be stably produced over a long period, is provided. It is a process of manufacturing inorganic nanofibers by electrospinning using a sol solution containing an inorganic component as a main component, characterized in that the sol solution contains a metal alkoxide having a high reactivity and a salt catalyst, and that the salt catalyst is an amine compound having an N—N bond, an N—O bond, an N—C?N bond, or an N—C?S bond.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: October 22, 2013
    Assignees: Shinshu University, Japan Vilene Company, Ltd.
    Inventors: Yasushi Murakami, Hisanao Usami, Tomohiro Nishikawa, Takashi Tarao, Rie Watanabe, Masaaki Kawabe, Takashi Nishitani
  • Patent number: 8551390
    Abstract: Embodiments of the present disclosure provide electrospinning devices, methods of use, uncompressed fibrous mesh, and the like, are disclosed.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: October 8, 2013
    Assignee: The UAB Foundation
    Inventors: Ho-Wook Jun, Ajay Tambralli, Bryan Adam Blakeney, Derrick Dean
  • Patent number: 8535583
    Abstract: The invention relates to a hydraulic binder product [12, 10] which includes a mixture of a hydraulic binder [38, 202], a polyvinyl alcohol [14, 204] and a gelling agent [54] which reacts with the polyvinyl alcohol and a method [8] of producing same.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: September 17, 2013
    Assignee: Tower Technology Holdings (Pty) Ltd.
    Inventor: Michael Windsor Symons
  • Patent number: 8524133
    Abstract: The present invention provides a method for manufacturing a film for a film capacitor making it possible to produce a film for a film capacitor which has a thickness of 10 ?m or less and which is excellent in a heat resistance and a voltage resistance at a high thickness accuracy by using a polyetherimide resin and provides as well a film for a film capacitor.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: September 3, 2013
    Assignee: Shin-Etsu Polymer Co., Ltd
    Inventors: Kenro Takizawa, Yuzo Morioka, Kazuhiro Suzuki, Michimasa Ote
  • Patent number: 8466076
    Abstract: The present invention pertains to a process for producing unmeltable polysilane-polycarbosilane copolymers which are soluble in inert solvents, comprising the steps providing the product of a disproportionation of a methylchlorodisilane or a mixture of several methylchlorodisilanes of the composition Si2MenCl6-n, wherein n=1?4, wherein the disproportionation was carried out with a Lewis base as a catalyst, wherein this product is a chlorine-containing, crude polysilane/oligosilane containing hydrocarbon groups, and thermally postcrosslinking the crude polysilane/oligosilane to a polysilane-polycarbosilane copolymer, characterized in that the chlorine content of the polysilane-polycarbosilane copolymer is lowered by reacting the crude polysilane/oligosilane with a substitution agent, by which chlorine bound therein is replaced with a chlorine-free substituent. Green fibers and low-oxygen/oxygen-free ceramic fibers with a very low chlorine content can be produced using this process.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: June 18, 2013
    Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
    Inventors: Arne Ruedinger, Juergen Clade, Heiko Spaniol, Dieter Sporn
  • Patent number: 8282873
    Abstract: Methods for controlled electrospinning of polymer fibers are described. The methods include spinning a polymer fiber from a fluid comprising a polymer in the presence of an electric field established between a plurality of collectors and a jet supply device controlling the dispersion characteristics of the fluid by applying a magnetic field created by at least one magnet located after the point of jet formation. Different voltages are applied to at least two collectors of the plurality of collectors. At least one magnet, located between the jet supply device and at least one collector, creates a magnetic field substantially transverse or substantially collinear to an electrospinning jet stream. The magnetic field changes direction of travel of the electrospinning jet stream.
    Type: Grant
    Filed: January 3, 2007
    Date of Patent: October 9, 2012
    Inventors: Victor Barinov, Kalle Levon
  • Publication number: 20120208421
    Abstract: Exemplary embodiments provide core-sheath nanofibers produced by coaxial electrospinning, fuser members comprising core-sheath nanofibers, and methods for forming core-sheath nanofibers that can include a core solution comprising a high performance polymer and sheath solutions comprising a solvent-soluble fluoropolymer or solvent-insoluble fluororesins and a sacrificial polymeric binder.
    Type: Application
    Filed: February 14, 2011
    Publication date: August 16, 2012
    Applicant: XEROX CORPORATION
    Inventors: Yu Qi, Carolyn Moorlag, Qi Zhang, Nan-Xing Hu
  • Publication number: 20120135659
    Abstract: The present invention relates to an improved insulation fiber material on the basis of mineral wool, as well as to a method for producing said improved insulation material.
    Type: Application
    Filed: February 2, 2012
    Publication date: May 31, 2012
    Inventor: Reinhard Preininger
  • Publication number: 20110300347
    Abstract: Various methods and systems are provided for the fabrication of patterned nanofibers. In one embodiment, a method includes generating a layer of electrospun nanofibers from a polymer solution and patterning the layer of electrospun nanofibers using ultraviolet (UV) lithography. The patterned electrospun nanofibers may then be thermally treated to form patterned carbon nanofibers. In another embodiment, a device includes a layer of patterned carbon nanofibers formed by generating electrospun nanofibers from a polymer solution, patterning the electrospun nanofibers using UV lithography, and converting the patterned electrospun nanofibers into patterned carbon nanofibers using a thermal treatment.
    Type: Application
    Filed: June 6, 2011
    Publication date: December 8, 2011
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Yong Kyu Yoon, Gloria J. Kim, Gwan-Ha Kim
  • Publication number: 20110274927
    Abstract: An inorganic fiber structure comprising inorganic nanofibers having an average fiber diameter of 3 ?m or less, in which an entirety including the inside thereof is adhered with an inorganic adhesive, and the porosity thereof is 90% or more, is disclosed.
    Type: Application
    Filed: January 14, 2010
    Publication date: November 10, 2011
    Inventors: Rie Watanabe, Takashi Tarao, Masaaki Kawabe, Tetsu Yamaguchi, Koei Kawakami
  • Patent number: 8022112
    Abstract: A plasticized ceramic-forming mixture and a method for stiffening the mixture, the mixture comprising a combination of inorganic powder, one or more plasticizing organic binders, a radiation-curable monomer, a photoinitiator, and water, and the method comprising stiffening the surfaces of extruded shapes of the mixture by applying electromagnetic energy to the surfaces following extrusion.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: September 20, 2011
    Assignee: Corning Incorporated
    Inventors: Michelle Dawn Fabian, Edward John Fewkes, Kevin Robert McCarthy
  • Publication number: 20100247909
    Abstract: The present invention provides a process for manufacturing a carbon nanofiber comprising: (a) mixing a carbon nanofiber precursor and camphor in a solvent to prepare a solution; (b) electric spinning the solution to obtain a nanofiber; (c) oxidative stabilizing the nanofiber; and (d) carbonizing the oxidative stabilized nanofiber, wherein camphor is volatilized to form micropores in the oxidative stabilization and carbonization. The present invention also provides a carbon nanofiber manufactured by the same.
    Type: Application
    Filed: December 29, 2006
    Publication date: September 30, 2010
    Applicant: Sungkyunkwan University Foundation for Corporate Collaboration
    Inventors: Younghee Lee, Kayhyeok An, Eunju Ra
  • Publication number: 20100164145
    Abstract: A process of manufacturing inorganic nanofibers, without using an organic polymer, using a highly reactive metal alkoxide such as titanium alkoxide or zirconium alkoxide, in particular, a process in which inorganic nanofibers can be stably produced over a long period, is provided. It is a process of manufacturing inorganic nanofibers by electrospinning using a sol solution containing an inorganic component as a main component, characterized in that the sol solution contains a metal alkoxide having a high reactivity and a salt catalyst, and that the salt catalyst is an amine compound having an N—N bond, an N—O bond, an N—C?N bond, or an N—C?S bond.
    Type: Application
    Filed: December 23, 2009
    Publication date: July 1, 2010
    Applicants: SHINSHU UNIVERSITY, JAPAN VILENE COMPANY, LTD.
    Inventors: Yasushi MURAKAMI, Hisanao USAMI, Tomohiro NISHIKAWA, Takashi TARAO, Rie WATANABE, Masaaki KAWABE, Takashi NISHITANI
  • Publication number: 20090166355
    Abstract: A microwave applicator assembly includes a microwave applicator that excites TE modes and provides a generally circular heating pattern in a lossy dielectric material. The microwave applicator has a processing chamber bounded by a circumferential wall in which a plurality of indents are formed. The microwave applicator assembly may further include a feed waveguide coupled to the microwave applicator for inputting microwaves into the processing chamber. The microwave applicator assembly may further include one or more choking sections in communication with the processing chamber to enhance heating efficiency and reduce microwave leakage.
    Type: Application
    Filed: June 29, 2007
    Publication date: July 2, 2009
    Inventors: Kevin Robert Brundage, Jacob George, Elizabeth Marie Vileno
  • Publication number: 20090110926
    Abstract: Single crystal MoO3 nanowires were produced using an electrospinning technique. High resolution transmission electron microscopy (HRTEM) revealed that the 1-D nanostructures are from 10-20 nm in diameter, on the order of 1-2 ?m in length, and have the orthorhombic MoO3 structure. The structure, crystallinity, and sensoric character of these electrostatically processed nanowires are discussed. It has been demonstrated that the non-woven-network of MoO3 nanowires exhibits higher sensitivity and an n-type response to NH3 as compared to the response of a sol-gel based sensor.
    Type: Application
    Filed: May 22, 2007
    Publication date: April 30, 2009
    Inventors: Pelagia-Irene Gouma, Aisha Suzette Haynes, Krithika Kalyanasundaram
  • Publication number: 20080305377
    Abstract: A method and apparatus for making a metallic nanofiber structure are disclosed. The method includes the steps of: providing a first solution including a first material and a second material, wherein the second material includes at least one metal; forming the first solution into composite fibers including the first material and the second material; and removing the first material from the composite fibers under conditions effective to produce a metallic nanofiber structure that includes a plurality of metallic nanofibers. Also disclosed are metallic nanofiber structures prepared according to a process of the present invention, which can be used as fuel cell catalysts. Fuel cells containing electrodes that include these metallic nanofiber structures are also disclosed.
    Type: Application
    Filed: March 17, 2008
    Publication date: December 11, 2008
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Jianglan SHUI, James C.M. LI
  • Publication number: 20080265469
    Abstract: Device and method for preparing filament yarn of composite nanofibers. The device includes pairs of electrospinning nozzles on a frame and filament guiding roller pair under the frame. The spouts of each pair of nozzles are oppositely facing. The method includes feeding polymer solutions to the pairs of nozzles, applying high DC voltage with opposite polarity respectively to each one of the pairs of nozzles, forming composite nanofibers by attracting nanofibers with opposite charge from each nozzle and striking together of the charged nanofibers, pulling/stretching the composite nanofibers to form filament yarn of composite nanofibers, drawing down the filament yarn of composite nanofibers from the first pair of nozzles and using it as a carrier to receive the nanofibers with opposite charge electrospun from the second pair of nozzles and coated by the same so as to form multi-layer (e.g., two- or more-layer) filament yarn of composite nanofibers.
    Type: Application
    Filed: November 10, 2006
    Publication date: October 30, 2008
    Inventors: Xinsong Li, Chen Yao, Fuqian Sun
  • Publication number: 20080213574
    Abstract: The present invention relates to the fields of chemistry and biology and more particularly to the field of biomaterials. The present invention includes amphiphilic fibers and membranes, which can be used for biomembranes and biocompatible devices. The present invention also relates to processes for preparing amphiphilic fibers and membranes from solutions comprising amphiphilic molecules. More particularly, the present invention relates to processes for preparing fibers and membranes from electrospinning solutions comprising amphiphilic molecules. The present invention further provides fibers and nonwoven membranes comprising amphiphilic fibers chosen from anionic surfactants, cationic surfactants, nonionic surfactants, phospholipids, sulfobetaines, lyotropic liquid crystalline molecules, and/or block copolymers.
    Type: Application
    Filed: July 31, 2007
    Publication date: September 4, 2008
    Inventors: Matthew G. McKee, John M. Layman, Matthew T. Hunley, Matthew P. Cashion, Timothy E. Long
  • Publication number: 20080191391
    Abstract: Multiple solid materials are introduced to a mixing vessel in defined proportion. They are melted by an electromagnetic induction heated susceptor and mixed simultaneously by the shearing action at the melt face of a second rotating susceptor. Material compounding takes place at the application site. Varying the physical structure of the susceptor or multiple susceptors processes materials of differing initial melt viscosity and particle size. Non-melting particulate material can be included in the mix. Reactive components can be combined at the application site.
    Type: Application
    Filed: February 11, 2008
    Publication date: August 14, 2008
    Inventor: Bernard Lasko
  • Patent number: 6808670
    Abstract: A process for manufacturing an inorganic material-based article comprising the steps of (1) forming a sol solution mainly composed of an inorganic component, (2) producing inorganic material-based gel fine fibers by extruding the resulting sol solution from a nozzle, and at the same time, applying an electrical field to the extruded sol solution to thin the extruded sol solution, and then, collecting inorganic material-based gel fine fibers on a support, (3) drying the collected inorganic material-based gel fine fibers to produce inorganic material-based article containing inorganic material-based dried gel fine fibers, and then, (4) sintering the inorganic material-based article containing inorganic material-based dried gel fine fibers to produce inorganic material-based article containing inorganic material-based sintered fine fibers.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: October 26, 2004
    Assignee: Japan Vilene Co., Ltd.
    Inventors: Masaaki Kawabe, Takashi Tarao, Kouji Kimura
  • Publication number: 20030042658
    Abstract: This invention concerns a process for coating a substrate, and an extrusion coatig structure. According to the present process, the coating is provided by producing a bimodal polyethylene composition by subjecting ethylene, optionally with hydrogen and/or comonomers to polymerization or copolymerization reactions in a multistage polymerization sequence of successive polymerization stages. The polymerization reactions are carried out in the presence of a single site catalyst capable of forming a composition which comprises a low molecular weight component with an MFR2 of 20 g/10 min or more and a density higher than the density of the composition, and a high molecular weight component, said composition having a melt flow rate MFR2 of 5 g/10 min or more and a density of 915-960 kg/m3. The composition is extruded on the substrate as such or by adding 10 wt-% or less, calculated from the total weight of the coating, of high pressure PE-LD by blending into the extrusion composition or by coextrusion.
    Type: Application
    Filed: September 30, 2002
    Publication date: March 6, 2003
    Inventors: Martti Vahala, Hannu Salminen, Arja Lehtinen
  • Patent number: 6156245
    Abstract: The present invention provides a microencapsulation method of a solid substance and the microencapsulated composition obtained from said method of: (i) preparing a dispersion phase comprising (a) a solution containing a substance which forms a middle layer and (b) a solid substance that is insoluble or difficult to dissolve in said solution, (ii) obtaining a solid substance which has a layer made of the substance which forms the middle layer by phase-separating the substance which forms the middle layer from the solution and (iii) reacting a monomer that is polymelizable by condensation in the presence of the solid substance that has a layer made of the substance which forms the middle layer.The above method can efficiently microencapsulate pharmaceutical active ingredients, pesticidal ingredients, aroma active ingredient and so on that are solid substances and affords an efficacious microencapsulated composition of solid substances.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: December 5, 2000
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yoshihiro Takebayashi, Nobuhito Ueda, Shugo Nishi
  • Patent number: 6153225
    Abstract: Described are an injectable formulation of nanoparticulate naproxen that produces minimal or no pain or burning sensation upon administration, and methods of making and using such a formulation. The injectable formulation comprises nanoparticulate naproxen having a povidone polymer adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 600 nm.
    Type: Grant
    Filed: August 13, 1998
    Date of Patent: November 28, 2000
    Assignee: Elan Pharma International Limited
    Inventors: Robert Lee, Lan De Castro
  • Patent number: 6149944
    Abstract: A preparation method for biodegradable polymeric microspheres using a solvent extraction method for biodegradable polymeric microspheres for treating a local inflammation disease using the same which are capable of effectively curing ozena such as sinusitis and a middle ear infection. Since a non-solvent of polymer is added into an outer aqueous phase in advance, the solidification of the polymer is implemented in a short time which, in turn, improves encapsulation of the therapeutic agent used.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: November 21, 2000
    Assignee: Korea Institute of Science and Technology
    Inventors: Seo Young Jeong, Ick Chan Kwon, Yong-Hee Kim
  • Patent number: 6139914
    Abstract: A microcapsule includes a shape memory resin shell wall formed with fissures that do not completely pass through the shell wall, and a dye encapsulated in the shell wall. The shell wall exhibits a temperature/pressure characteristic such that the fissures open, when the shell wall is squashed and compacted under a predetermined pressure at a predetermined temperature, whereby a seepage of the dye frog the squashed and compacted shell wall through the opened fissures is adjustable.
    Type: Grant
    Filed: October 23, 1998
    Date of Patent: October 31, 2000
    Assignee: Asahi Kogaku Kogyo Kabushiki Kaisha
    Inventors: Minoru Suzuki, Hiroshi Orita, Hiroyuki Saito, Katsuyoshi Suzuki, Koichi Furusawa
  • Patent number: 6126872
    Abstract: High concentration drag reducing agents may be prepared by microencapsulating polymer drag reducing agent. The microencapsulation may be performed prior to, during, or after the polymerization of monomer into effective drag reducing polymer. If encapsulation is done before or during polymerization, a catalyst may be present, but little or no solvent is required. The result is very small scale bulk polymerization within the microcapsule. The inert capsule or shell may be removed before, during or after introduction of the microencapsulated drag reducer into a flowing liquid. No injection probes or other special equipment is expected to be required to introduce the drag reducing slurry into the liquid stream, nor is grinding (cryogenic otherwise) of the polymer necessary to form a suitable drag reducing agent.
    Type: Grant
    Filed: January 27, 1998
    Date of Patent: October 3, 2000
    Assignee: Baker Hughes Incorporated
    Inventors: Nagesh S. Kommareddi, Lawrence J. Rzeznik
  • Patent number: 6123988
    Abstract: This invention relates to the process for the preparation of polyurethane with controlled particle size and shape. More, particularly it relates to the production of polyurethane microspheres from a diol and diisocyanate by dispersion polymerization in presence of a steric stabilizer and a catalyst in an organic solvent at a controlled temperature, and finally separating the spherical polyurethane particles from the reaction mixture by conventional means.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: September 26, 2000
    Assignee: Council of Scientific & Industrial Research
    Inventors: Lalgudi Srinivasan Ramanathan, Swaminathan Sivaram
  • Patent number: 6120839
    Abstract: Disclosed herein are novel electrophoretic displays and materials useful in fabricating such displays. In particular, novel encapsulated displays are disclosed. Particles encapsulated therein are dispersed within a suspending, or electrophoretic, fluid. This fluid may be a mixture of two or more fluids or may be a single fluid. The displays may further comprise particles dispersed in a suspending fluid, wherein the particles contain a liquid. In either case, the suspending fluid may have a density or refractive index substantially matched to that of the particles dispersed therein. Finally, also disclosed herein are electro-osmotic displays. These displays comprise at least one capsule containing either a cellulosic or gel-like internal phase and a liquid phase, or containing two or more immiscible fluids. Application of electric fields to any of the electrophoretic displays described herein affects an optical property of the display.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: September 19, 2000
    Assignee: E Ink Corporation
    Inventors: Barrett Comiskey, Joseph M. Jacobson
  • Patent number: 6110503
    Abstract: A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymer, an active agent, and a solvent. An immiscible second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The two phases are immersed in a quench liquid that includes a quench medium and a quantity of the solvent. The quantity of the solvent is selected to control a rate of extraction of the solvent from the first phase. The first phase is isolated in the form of microparticles. Also disclosed is a microencapsulated active agent prepared by the method for preparing biodegradable, biocompatible microparticles.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: August 29, 2000
    Assignee: Alkermes Controlled Therapeutics Inc.
    Inventors: Michael E. Rickey, J. Michael Ramstack, Danny H. Lewis
  • Patent number: 6106946
    Abstract: Provided are microcapsules enclosing therein a magnetic fluid, which are useful for imparting sound-absorbing and insulating ability to building materials, etc. by incorporation thereinto or adhesion thereto by means of an adhesive, and processes for producing the microcapsules. The heat-expandable microcapsule of the present invention comprises (i) a shell composed of a thermoplastic resin and (ii) a magnetic fluid which is a dispersion of magnetic substance fine particles having an average particle diameter of 5-200 nm in a hydrophobic organic solvent and a hydrophobic liquid foaming agent, both enclosed in the shell. The hollow microcapsule of the present invention comprises (i) a shell composed of a thermoplastic resin, and (ii) a magnetic fluid which is a dispersion of magnetic substance fine particles having an average particle diameter of 5-200 nm in a hydrophobic organic solvent and a vacant cell both included in the shell.
    Type: Grant
    Filed: September 11, 1998
    Date of Patent: August 22, 2000
    Assignees: Matsumoto Yushi-Seiyaku Co., Ltd., Nitto Boseki Co., LTD
    Inventors: Koji Tanaka, Toshihiko Shibamoto, Akihiko Nishizaki
  • Patent number: 6103269
    Abstract: The invention relates to accurately meterable shaped articles, for example granules or pellets, containing hydrophilic macromolecules, active compounds and optionally further pharmaceutically acceptable structure-forming substances and auxiliaries, the active compound being present in a matrix in dissolved, suspended or emulsified form, and a novel process for the production of these shaped articles, the process being particularly economically and ecologically acceptable, and use of the shaped articles as medicaments, in which the bioavailability, shelf life and tolerability is increased. Using the shaped articles or mixtures according to the invention, intermediates or final products for pharmacy, cosmetics, diagnosis, analysis or dietetics (healthcare) can additionally be advantageously prepared.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: August 15, 2000
    Assignee: Alfatec-Pharma GmbH
    Inventors: Jens-Christian Wunderlich, Ursula Schick, Jurgen Werry, Jurgen Freidenreich
  • Patent number: 6103271
    Abstract: Methods are provided for forming spherical multilamellar microcapsules having alternating hydrophilic and hydrophobic liquid layers, surrounded by flexible, semi-permeable hydrophobic or hydrophilic outer membranes which can be tailored specifically to control the diffusion rate. The methods of the invention rely on low shear mixing and liquid-liquid diffusion process and are particularly well suited for forming microcapsules containing both hydrophilic and hydrophobic drugs. These methods can be carried out in the absence of gravity and do not rely on density-driven phase separation, mechanical mixing or solvent evaporation phases. The methods include the process of forming, washing and filtering microcapsules. In addition, the methods contemplate coating microcapsules with ancillary coatings using an electrostatic field and free fluid electrophoresis of the microcapsules. The microcapsules produced by such methods are particularly useful in the delivery of pharmaceutical compositions.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: August 15, 2000
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Dennis R. Morrison, Benjamin Mosier
  • Patent number: 6103378
    Abstract: A process for producing a microencapsulated system comprising the steps of: (a) emulsifying a solution of color precursor in a solvent as a first internal phase and a diluent as a second internal phase in an external phase to produce discrete droplets of each of said first and second phases; and (b) encapsulating said droplets, is disclosed. A recording sheet is also disclosed which comprises a substrate having a layer of microencapsules containing a color precursor solution and microcapsules containing a diluent. Preferably the microcapsules are clusters of gelatin capsules.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: August 15, 2000
    Assignee: The Mead Company
    Inventors: Peter C. Yao, Datta G. Mislankar, Glenn E. Bane, John K. Rourke
  • Patent number: 6099864
    Abstract: Disclosed are microcapsules comprising a polymer shell enclosing two or more immiscible liquid phases in which a drug, or a prodrug and a drug activator are partitioned into separate phases, or prevented from diffusing out of the microcapsule by a liquid phase in which the drug is poorly soluble. Also disclosed are methods of using the microcapsules for in situ activation of drugs, where upon exposure to an appropriate energy source the internal phases mix and the drug is activated in situ.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: August 8, 2000
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: Dennis R. Morrison, Benjamin Mosier
  • Patent number: 6096344
    Abstract: A composition for the sequestration and sustained delivery of an active ingredient in the form of porous particles, the composition comprising the product of the controlled dehydration of particles formed by the reaction of a polymeric anionic material with a polyvalent cation. The composition may be loaded with an active ingredient by soaking the particles in a solution of the active ingredient; and may then be dehydrated. They may then be soaked in a solution of a polymeric cationic material, to form particles providing the controlled release of the active ingredient.
    Type: Grant
    Filed: February 24, 1997
    Date of Patent: August 1, 2000
    Assignee: Advanced Polymer Systems, Inc.
    Inventors: Lin-Shu Liu, Michael Froix, Jorge Heller, Steven Y. Ng
  • Patent number: 6090317
    Abstract: This invention provides a heterotelechelic oligomer or polymer which is represented by the following formula: ##STR1## wherein A denotes a sugar residue, L denotes a linkage group represented by the following formula ##STR2## wherein R.sup.1 and R.sup.2 independently denote lower alkyl, aralkyl or aryl,X denotes a single bond or --CH.sub.2 CH.sub.2 --, Z denotes a group forming an unsaturated ester or ether, or a functional group such as halogen which binds to --CH.sub.2 CH.sub.2 --, n denotes an integer of 5-10,000, and m denotes an integer of 0 or 2-10,000.This invention also provides a process to produce the above oligomer or polymer, and further a high molecular-micelle with use of a polyethylene oxide-polyester block polymer which has a sugar residue at its terminal. Said oligomer or polymer is expected to exhibit excellent bioavailability, and is also expected to be utilized in the field such as carriers for drug delivery or diagnostic reagents.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: July 18, 2000
    Assignee: Kazunori Kataoka
    Inventors: Kazunori Kataoka, Yukio Nagasaki, Masao Kato, Teruo Okano, Teruo Nakamura
  • Patent number: 6074673
    Abstract: The present invention is directed to an implantable, slow-release, self-absorbing, biologically compatible drug delivery system such as slow-release pharmaceutical compositions, including for example, slow-release, allergy desensitization compositions containing one or more allergens in combination with a biologically-compatible, self-absorbing matrix. The present system is useful for treating disorders including, for example, infections, deficiencies or allergies. The present invention is also directed to methods of treating a patient suffering from a disorder, as well as methods for desensitizing a patient to one or more allergens. The present invention also relates to a device for implanting the present composition in a patient.
    Type: Grant
    Filed: April 22, 1996
    Date of Patent: June 13, 2000
    Inventor: Manuel Guillen
  • Patent number: 6063323
    Abstract: A process and installation are provided for making an extruded sintered ceramic product. The method involves extruding a moist profile and simultaneously drying it with microwave radiation as it is extruded. As the profile is extruded and dried, it is supported at a position where it has been at least partially dried. The installation comprises extrusion means for extruding a moist profile, support means for supporting the extruded profile at an at least partially dried part thereof, and a microwave radiation source for directing microwaves at the profile.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: May 16, 2000
    Assignee: Implico B.V.
    Inventors: Paul F Fuls, Andre K Joubert, Diederik Kapp
  • Patent number: 6048551
    Abstract: A controlled release delivery system includes a functional gene vector in a biodegradable polymeric microsphere encapsulating the vector. The present invention further provides a method of making a controlled release delivery system by encapsulating the functional gene vector in a biologically degradable polymeric microsphere.
    Type: Grant
    Filed: March 27, 1997
    Date of Patent: April 11, 2000
    Inventors: John M. Hilfinger, Beverly L. Davidson, Steven J. Beer, John R. Crison, Gordon L. Amidon
  • Patent number: 6045835
    Abstract: A method of encapsulating an amphiphilic flavor or fragrance compound into a microcapsule having a hydrogel shell and an oil core. The flavor or fragrance compound is transported into and solubilized in the core by partition coefficient equilibrium using water in the capsule wall to transport the compound into the core. Microcapsules made by the method of the invention may have a wall thickness and contain a high concentration of the flavor or fragrance compound that has not previously been feasible.
    Type: Grant
    Filed: October 9, 1997
    Date of Patent: April 4, 2000
    Assignee: Givaudan Roure (International) SA
    Inventors: Jon C. Soper, Young D. Kim, Margaret T. Thomas
  • Patent number: 6039900
    Abstract: A dispersion is formed of aqueous polymer particles in a non-aqueous liquid and a stabiliser is covalently reacted on to the particles.
    Type: Grant
    Filed: June 30, 1998
    Date of Patent: March 21, 2000
    Assignee: Allied Colloids Limited
    Inventors: Kenneth Charles Symes, Kishor Kumar Mistry