Abstract: A method and apparatus for identifying a sample in a container, provide for the container with the sample being disposed relative to a resonator, a high-frequency signal being coupled into the resonator for exciting a resonant mode of the resonator, the resonant electric field of the resonator penetrating part of the sample in the container, the resonance curve of at least one resonant mode being measured with and without the sample, and the sample being identified based on the determined change in the resonance frequency compared to a measurement without sample.

Abstract: An apparatus and method for correcting magnetic resonance temperature measurements is disclosed. In one aspect, the method identifies monitoring regions of interest outside a therapeutic region of interest. Next, a pulse sequence sensitive to changes in T1 and proton density is used to measure the temperature changes in these regions. Next, the PRFS is measured in these same regions. The PRFS in these regions will be caused both by the desired shift from temperature change, and the undesired shift from background magnetic field changes. Using the measured temperature changes from the T1-method, the component of the PRFS due to actual temperature changes is subtracted from the PRFS method, leaving only the component caused by the unwanted magnetic field changes. This analysis is performed separately for each region. At the end of this step, one has measured the change in background magnetic field within each region.

Abstract: A noble gas is administered to a subject to fill the lungs and magnetic resonance elastography image data is acquired while vibrations are applied to the chest wall. Shear waves are established in the gas-filled lungs by the vibrations and a shear modulus image is reconstructed from the MRE image data that may be used in the diagnosis of lung disease.

Abstract: The invention describes a process for the determination of the concentration distribution and size distribution of lipoprotein classes in body fluids, e.g. blood. For this purpose, NMR spectra of a sample to be analysed are measured by magnetic field gradient intensities and temperatures under different diffusion-weighted measuring conditions selected according to different pulse programs (e.g. PFG-STE, PFG-LED etc) and consequently in a differentiated manner according to the relaxation times. The different effects of these measuring conditions on the intensity/line form of the NMR signals of the individual lipoprotein classes are determined and permit the determination of a concentration distribution/size distribution of the individual lipoprotein classes.

Abstract: A method and system for imaging using labeled contrast agents and a magnetic resonance imaging (MRI) scanner are provided. The method comprises performing a prescan at a frequency selected to be substantially similar to a frequency of the labeled contrast agent and performing an examination scan at the frequency of the labeled contrast agent substantially immediately after administering the labeled contrast agent to a subject.

Abstract: A sample holder for fixing and transporting a sample vial (1) within an NMR configuration comprising an outer shell (4) and a continuous hollow space disposed inside the outer shell (4) and extending along its axis for receiving the sample vial, is characterized in that a clamping device that can be switched on and off and a switching element (6) are provided inside the hollow space, wherein, in the activated state, the clamping device fixes a sample vial (1) that is introduced into the sample holder, the switching element (6) can be operated from the outside, and the clamping device can be deactivated using the switching element (6) such that, in the deactivated state, the sample vial (1) inserted into- or removed from the sample holder is not fixed. Such a sample holder may be used to realize an automatic supply device for changing NMR sample vials which has a very compact structure and can be mounted using little space.

Abstract: Magnetic resonance imaging method and apparatus are provided for mapping the internal or bulk motion of an object by labeling the phase of a specimen magnetization with a selected spatial function and measuring changes in the phase of the magnetization. The spatial function is selectable to provide magnetization phase modulation corresponding to displacements in a selected direction, such as a radial or azimuthal direction. Methods and apparatus for producing images based on magnetization phase modulation acquire image data based on stimulated echos and stimulated anti-echos. In an embodiment, a series of 180 degree pulses produces alternating stimulated and stimulated anti-echos that are measured and assigned to respective images.

Abstract: A system and method of MR imaging is disclosed that includes reconstruction of MR images with uniform or homogeneous fat suppression. An imaging process is performed using partial asymmetric acquisitions in conjunction with zero-filling of k-space for dynamic contrast-enhanced imaging. Data acquisition is carried out in a relatively short period of time which reduces scan time, reduces the likelihood of subject discomfort and motion-induced artifacts, and increases patient throughput.

Abstract: A phantom for Diffusion Tensor Imaging (DTI) to measure the main physical quantities of diffusion tensors, such as diffusion anisotrophy, a diffusion principal axis and a route of the diffusion principal axis, and to evaluate the accuracy of DTI are provided. The phantom for diffusion tensor imaging includes: an outer container providing a space; materials for diffusion measurement located in the space of the outer container and formed of bunches of microtubes; and materials for fixing located in the space of the outer container to fix the materials for diffusion measurement to a specific location.

Abstract: A method of comparing micro-electronic devices. The method includes: placing a first micro-electronic device in a sample chamber of a magnetic resonance imaging machine, subjecting the first micro-electronic device to a magnetic field and a radio frequency pulse, turning off or adjusting the magnetic field and detecting a first returned RF pulse from the first micro-electronic device and storing first data relating to the first returned RF pulse; placing a second micro-electronic device in the sample chamber, subjecting the second micro-electronic device to the magnetic field and the radio frequency pulse, turning off or adjusting the magnetic field and detecting a second returned RF pulse from the second micro-electronic device and storing second data relating to the second returned RF pulse; and comparing the first data to the second data and determining if the second micro-electronic device is essentially identical to the first micro-electronic device based on the comparing.

Abstract: A system and method for determining the temporal resolution of a tomographic imaging device uses an apparatus to drive one or more dynamic phantoms composed of multiple materials. The apparatus is placed at or near the isocenter of the imaging device and the one or more phantoms are moved to produce a plurality of dynamic features, each having a specified frequency. The dynamic features are imaged with the device and the acquired image data corresponding to the dynamic features is analyzed to determine a temporal modulation transfer value at each of the known specified frequencies. The temporal resolution of the imaging device is determined using these temporal modulation transfer values.

Abstract: An improved imaging technique and apparatus for direct temporal encoding of spatial information of an object is presented. The signal collected from the object after application of excitation energy in a magnetic field is directly representative of the spatial position of the object without the need for the signal to undergo mathematical transformation. This is a result of the excitation scheme that generates transverse magnetization across the field of view that is a function of X (read-out) and Z (slice select) positions, resulting in a two-dimensional phase profile that, upon application of a constant gradient along the Z axis, elicits a signal that is directly attributable to the spatial position along the read-out dimension without application of mathematical transformation.

Abstract: A phantom for use in an MRI or MRS system includes an array of subresolvable compartments that are each connected to receive fluid from one of a plurality of fluid reservoirs. The array of compartments is divided into sub-arrays which differ from each other by the mix of compartments in each sub-array receiving fluids from the different reservoirs. Studies can be performed with the phantom by filling the compartments with selected fluids from the reservoirs, disconnecting the reservoirs and placing the phantom in the system bore. The phantom can be reused in other studies by replacing the fluids with different fluids.

Abstract: There is disclosed an NMR measurement method of observing plural magnetization transfer patterns in one experiment and observing their respective time-modulated, evolved chemical shifts. In an earlier portion of a pulse sequence, a transition is made from in-phase magnetizations to antiphase magnetizations using RF pulses. In an intermediate portion of the sequence, the antiphase magnetizations are interchanged using 90° RF pulses. In a later portion of the sequence, a transition is made from the antiphase magnetizations to the in-phase magnetizations using other RF pulses. Simultaneously with the interchange of the magnetizations, evolution of chemical shifts is performed by a constant-time evolution technique. In the earlier and later portions of the pulse sequence, evolutions of the chemical shifts can be performed simultaneously because the magnetizations of two nuclei are in lateral magnetization state.

Abstract: A method for detecting the presence of precipitants in a hydrocarbon stream, the method comprising introducing at least a portion of the hydrocarbon stream into a measurement chamber of an NMR measuring device, assaying the fluids in the chamber with proton nuclear magnetic resonance to obtain NMR signals, and processing the NMR signals to detect the formation of precipitants in the hydrocarbon stream. The method may be carried out at first and second locations, and NMR signals obtained at the two locations compared to detect precipitation of precipitant between the two locations. A method of monitoring the water content of a hydrocarbon stream in a flowline comprising introducing at least a portion of the hydrocarbon stream into an NMR measuring device, measuring a baseline NMR water signal of the hydrocarbon stream and comparing subsequent NMR water signals with the baseline NMR water signal to detect changes in the water content of the hydrocarbon stream.

Abstract: In a method for determining an absolute number of electron spins in an extended sample (3) with the assistance of an apparatus for measuring magnetic resonance, the extended sample (3) is disposed within a measurement volume (2) of a radiofrequency RF resonator (1) of the apparatus during an electron spin resonance measurement (ESR).

Abstract: A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Arterial and venous voxels are automatically identified in the images using either of two disclosed methods. The signals from identified arterial voxels are used to produce an arterial contrast enhancement reference curve that is used to segment arterial voxels by a correlation process. Venous voxels are segmented in the same manner using a calculated venous contrast enhancement reference curve.

Abstract: Monitor scans are performed before imaging scans with respect to a patient injected with a contrast agent. Magnetic resonance images of a plurality of slices of the patient are acquired, usually continuously, in the monitor scans. Projection images are generated from the magnetic resonance images for the plurality of slices, and these projection images are dynamically displayed images. The operator observes the monitor image and issues an instruction for imaging scans. Since a projection image is displayed as the monitor image, then even if a blood vessel is distributed over a three-dimensional area, the operator is still able to ascertain accurately the timing at which the contrast agent reaches the diagnostic region.

Abstract: The invention relates to an NMR analysis system and method for obtaining an NMR signal from a liquid solution enhanced in relation to the value that it would have on the basis of the thermodynamic equilibrium. It has been discovered in a surprising manner that if the spins of the cores of a highly-polarized polarization source and the spins of the cores of the liquid solution are irradiated such that a polarization transfer, such as a Hartmann-Hahn transfer, of the spins of the cores of the source to the spins of the cores of the liquid solution is carried out by means of a coherent coupling resulting from the dipolar field created by the cores of the source, an NMR signal of the liquid solution is obtained, said signal being significantly enhanced in relation to the value it would have on the basis of the thermodynamic equilibrium.

Abstract: Navigator methods are disclosed that are based on detecting a flow-sensitive signal within a subject, and using the position of the signal to track subject motion between imaging sequences. In a disclosed embodiment, the fast-moving blood volume in the left ventricle of the heart is detected and used as a reference point to correct for cardiac motion that results from respiratory motion in a subject. The navigator based on the position of the fast-moving blood volume in the left ventricle may be applied prospectively to shift a subsequent imaging slice to compensate for subject motion, and thereby provide MRI images with increased clarity and resolution.

Abstract: A phantom for use in an MRI or MRS system includes an array of subresolvable compartments that are each connected to receive fluid from one of a plurality of fluid reservoirs. The array of compartments is divided into sub-arrays which differ from each other by the mix of compartments in each sub-array receiving fluids from the different reservoirs. Studies can be performed with the phantom by filling the compartments with selected fluids from the reservoirs, disconnecting the reservoirs and placing the phantom in the system bore. The phantom can be reused in other studies by replacing the fluids with different fluids.

Abstract: The present invention generates a visual display of metabolomic data compiled by a database and associated processor. More particularly, the present invention provides a database for automatically receiving a three-dimensional spectrometry data set for a group of samples. The present invention also provides a processor device for manipulating the data sets to produce plots that are directly comparable to a plurality of characteristic plots corresponding to a plurality of selected metabolites. Furthermore, the processor device may generate a visual display indicating the presence of the selected metabolites across the group of samples. Thus, the present invention enables a user to analyze a series of complex data sets in a visual display that may indicate the presence of the selected metabolites across the group of samples. Furthermore, the visual display generated by embodiments of the present invention also expedites the subjective analysis of the spectrometry data sets.

Abstract: A method for estimating a concentration of a substance in a test sample of formation fluid, comprising measuring an NMR parameter of a first sample of formation fluid to obtain a first measurement, adding a known quantity of the substance to the first sample to produce a modified sample, measuring the NMR parameter of the modified sample to obtain a second measurement; and determining a relation between the concentration of the substance and a function of the NMR parameter using the first and second measurements and the NMR parameter of the substance.

Abstract: A method for coupling a gas chromatograph (21) to an NMR spectrometer, wherein the carrier gas present at the outlet of a separating column (23) of the gas chromatograph (21) including a sample contained in the carrier gas is supplied via a heated transfer line (1) to a collecting device (2) for the sample contained in the carrier gas, is characterized in that the carrier gas containing the sample is introduced into a collecting liquid (8) in the collecting device (2), and the sample is collected in the collecting liquid (8), wherein the collecting liquid (8) is suitable as an NMR solvent for the sample. The sample loss of the coupling method is reduced.

Abstract: The present invention includes a method and apparatus to perform rapid multi-slice MR imaging without ECG gating or requiring breath-holding that is capable of renal profusion analysis and angiographic screening. An ungated interleaved pulse sequence is applied in rapid succession, followed by a delay interval. The ungated interleaved pulse sequence is repeatedly played out with the predefined delay interval between each application of the pulse sequence. The resulting images provide not only a series of temporal phases of contrast-enhanced blood uptake for renal profusion analysis, but also provide enough dynamic range to include angiographic screening of the renal arteries.

Abstract: Magnetic resonance measurement methods for determining the mass of samples are provided in which magnetic field homogeneity is determined, compensation is provided for potential drifts in the measuring system, and the presence of metal in samples is determined. The methods include applying a magnetic field in a first direction in an interrogation zone for creating a net magnetisation within a sample located within the interrogation zone; applying an alternating magnetic field in a second direction in the interrogation zone for temporarily changing the net magnetisation of the sample located within the interrogation zone; monitoring energy emitted by the sample as the net magnetisation of the sample returns to its original state and generating an output signal having a characteristic which is proportional to the energy emitted; and comparing the output signal of the monitoring with other data.

Abstract: A technique is set forth for MR spectroscopy that is capable of reducing signal overlap between metabolite signals for improved clinical analysis of metabolite content. The technique includes varying an echo time across a scanning dimension. Once a span of echo time for an acquisition dimension is determined, and the number of acquisition data points is known, a variance between echo times can be determined. A pulse sequence with differing echo times is then applied for each frame, and after data is acquired, an image is reconstructed that significantly improves metabolite signal separation.

Abstract: Magnetic resonance methods are provided for determining the mass of samples in vials (1) in a production line, each sample having a net magnetisation capability, including the steps of applying a first magnetic field in a first direction in an interrogation zone (25) for creating a net magnetisation within a sample located within the interrogation zone (25), applying an alternating magnetic field in a second direction in the interrogation zone (25) for temporarily changing the net magnetisation of the sample located within the interrogation zone (25), monitoring energy emitted by the sample as the net magnetisation of the sample returns to its original state and generating an output signal whose current amplitude is proportional to the energy emitted, comparing the current amplitude with like data obtained from at least one similar sample of known mass, and determining the mass of the sample.

Abstract: Haemodynamic indices of an organ or a part of tissue are determined from a time series of tomographic data obtained by means of Magnetic Resonance Imaging. Maps of indices are produced, being significant of the dynamics of the capillary tissue flow acquired during rapid bolus injection of a tracer that stays mainly intravascular. The method may be used for evaluating the efficacy of a drug on an organ, or for obtaining information of the likelihood of recovery of an organ or part of tissue upon or during a period of insufficient vascular supply or during the progression of a chronic disease. The method may be used for discriminating between relevant therapy of an organ.

Abstract: A method for determining the modulation transfer function (MTF) of a magnetic resonance system is described. The method involves recording, by means of the relevant magnetic resonance system, a cross-sectional image of stripe structure (S, S1, S2, S3, S4, S5, S6) of a phantom (1) with a number of alternately arranged magnetic resonance device-active material layers (6) and magnetic resonance device-inactive material layers (7) with a prespecified periodicity running at right angles to the cross-sectional recording plane (BE), with the magnetic resonance device-active material layers (6) being thicker than the magnetic resonance device-inactive material layers (7). Subsequently the quotient of the standard deviation (ó) and of the mean (<|b(x)|>) of the intensity values of the pixels located in a specific Region of Interest (ROI) are determined and defined on the basis of the quotient of the modulation transfer function determined.

Abstract: In a magnetic resonance tomography apparatus employing a FISP pulse sequence, the pulse sequence is repeated with a repetition time TR with different phase-coding gradient directions and with an alternating operational sign of the flip angle ?. The gradient pulse trains are thereby completely balanced. A phase increment ??=? is generated in addition to the alternating operational sign of the flip angle ? between successive excitation pulses, so that the steady state signals for a first and a second spin ensemble optionally have either identical or reversed signal polarities. A first dataset on the basis of identical signal polarities and a second dataset on the basis of reversed signal polarities are obtained by means of the free selection of the mutual signal polarities. A pure image of the first and the second spin ensembles is thus obtained by the addition and/or subtraction of the first and second datasets.

Abstract: A magnetic resonance imaging (“MRI”) system and method of correcting for the motion of a subject during an MRI scan. The motion of a subject in an MRI scan is corrected by acquiring nuclear magnetic resonance (“NMR”) spectra of an ordered material attached to a subject, wherein there is a dependence on the NMR spectra of the ordered material's orientation in a magnetic field, and determining an orientation of the subject. Correction information is then supplied to a primary spectrometer channel which is used to execute an MRI scan, and an imaging pulse sequence of the MRI scan is adjusted to correct the subject's orientation.

Abstract: A Nuclear Magnetic Resonance (NMR) probe device (20) is disclosed. NMR probe device (20) includes a plurality of detection coils (30, 40) each operable to detect a signal from a corresponding one of a plurality of samples (34, 44) undergoing NMR analysis. Also included is a plurality of tuning circuits (31, 41, 38, 48) each coupled to one of detection coils (30, 40) to tune the one of the detection coils (30, 40) to a corresponding resonant frequency for the NMR analysis of the corresponding one of the samples. An electromagnetic shield (22) is positioned between a first one of the detection coils (30, 40) and a second one of the detection coils (30, 40) to isolate the first one of the detection coils (30, 40) and the second one of the detection coils (30, 40) from each other.

Abstract: A PIN diode switching system is provided, particularly for the transmission stage of a mobile radio telephone, in which, when the PIN diode switching system is in a reverse-bias state, a PIN diode is isolated from its power supply via a high-impedance switch and is, thus, biased by its self-rectification to a radio-frequency voltage in order to suppress harmonic formation and radio-frequency attenuation.

Abstract: A device for simulating a sample of gas having a specific level of polarization when measured by a NMR pickup coil includes an active circuit loosely coupled to the NMR pickup coil. The active circuit responds as a hyperpolarized gas having the specific level of polarization when measured by the NMR pickup coil.

Abstract: A plurality of time-series NMR signal groups are obtained before and after administration of a contrast agent, on an individual image basis, for the same region of the object. One of the obtained NMR signal group obtained before the administration is defined as standard data, a plurality of subtracted NMR signal groups are produced by performing subtraction between the standard NMR signal group and each of the other NMR signal groups obtained after the administration. The subtracted NMR signal groups are subjected to weighted-addition or cumulative addition to obtain an MR angiographic image excellent in contrast throughout the image, in which processes through which an optimal concentration portion of the contrast agent moves are joined into a single image.

Abstract: Phantoms for testing and measuring the performance of magnetic resonance imaging (MRI) and x-ray computed tomography (CT) imaging systems have regions of precisely controlled magnetic resonance and x-ray absorption imaging properties. These regions contain subresolvable regions, or distinct micro regions, with pre-selected magnetic resonance or x-ray absorption properties, called scatterers. The regions are precisely positioned so as to define patterns which form images from which the performance of the imaging system can be evaluated to assure the quality of the images. The phantoms can reveal the combined influences of all the stages in the imaging chain in terms of modulation transfer function and resolution limits as well as other artifacts and defects in the system such as aliasing and degraded spatial frequency response which cannot be evaluated with conventional phantoms.

Abstract: Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned de superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Abstract: Nuclear magnetic resonance spectroscopy catheter probe comprising a permanent magnet arrangement (1,2,3,4) for generating a static magnetic field of suitable intensity and homogeneity for analysing a sample of fluid flowing into a catheter (6) traversing the permanent magnet arrangement. The probe further comprises an arrangement of electronic circuits (8,9) responsible for the excitation and detection of the nuclear magnetic resonance signal and at least one coil (7) to expose the fluid sample to the excitation signal and to collect the returned nuclear magnetic resonance signal.

Abstract: Tissue-mimicking material suitable for phantoms for use with at least ultrasound and MRI have sections of material in contact with each other which mimic ultrasound and magnetic resonance imaging properties of human tissues, and preferably also computed tomography properties, so that the phantom can be used for the testing of imaging by various types of medical imagers. A suitable tissue-mimicking material for use in phantoms of this type includes an aqueous mixture of large organic water soluble molecules, a copper salt, a chelating agent for binding the copper ions in the salt, and a gel-forming material. Small glass beads may be intermixed therewith to provide a selected ultrasound attenuation coefficient without substantially affecting the MRI properties of the material. Larger glass beads may be used in a section to control primarily the ultrasound backscatter coefficient without significant effect on the ultrasound attenuation coefficient.

Abstract: The invention features methods of selecting chemical peaks from two-dimensional magnetic resonance spectra for one-dimensional extraction and quantification methods using these one-dimensional extractions. The methods permit enhanced differentiation of particular peaks in two-dimensional magnetic resonance spectroscopy and allow for quantification of chemical concentrations in test samples, such as human brain tissue, having complex magnetic resonance spectra due to the presence of numerous chemicals. These new techniques can be used to provide information about the concentrations of a variety of chemicals, including metabolites, in both biological and non-biological media.

Abstract: An implantable nuclear magnetic resonance spectrometer for measuring the chemical composition of a fluid or for measuring the flow rate of the fluid. The spectrometer includes a housing and a catheter traversing across the housing so that a fluid external to the housing may flow through the catheter within the housing. A permanent magnet is disposed within the housing and generates an intense homogenous magnetic field in the vicinity of the catheter. An electronic circuit is disposed within the housing for detecting and formatting a nuclear magnetic resonance excitation signal. An excitation coil is connected to the electronic circuit and is disposed about the catheter to expose the fluid within the catheter to the excitation signal and to collect the nuclear magnetic resonance excitation signal.

Abstract: An apparatus and method for remote NMR/MRI spectroscopy having an encoding coil with a sample chamber, a supply of signal carriers, preferably hyperpolarized xenon and a detector allowing the spatial and temporal separation of signal preparation and signal detection steps. This separation allows the physical conditions and methods of the encoding and detection steps to be optimized independently. The encoding of the carrier molecules may take place in a high or a low magnetic field and conventional NMR pulse sequences can be split between encoding and detection steps. In one embodiment, the detector is a high magnetic field NMR apparatus. In another embodiment, the detector is a superconducting quantum interference device. A further embodiment uses optical detection of Rb-Xe spin exchange. Another embodiment uses an optical magnetometer using non-linear Faraday rotation. Concentration of the signal carriers in the detector can greatly improve the signal to noise ratio.

Abstract: The present invention relates to methods to image the skin surface in order to view intercellular and intracellular structure. In particular, the invention relates to use of a compound (e.g., fluorescent dye) to enhance contrast and obtain better imaging.

Abstract: For simultaneously determining the analytical NMR spectra of a number of samples placed suitably arranged in the measuring site of an NMR measuring apparatus, spatially and timely varying magnetic fields are used. The resulting signals are spatially resolved by a suited processing, for example Fourier transform. Surprisingly, from these signals, analytical NMRs of high resolution can be obtained for each sample. The method can be applied to two-dimensional arrangements of samples, for example a bundle of capillaries imitating a conventional NMR sample tube or a well plate, or three-dimensional arrangements, for example stacks of well plates. The method allows the determination of NMR spectra for analysis or for comparison with anterior spectra for long time behavior studies and quality assessment with only a fraction of time needed for measuring the samples individually.

Abstract: The invention is directed to a method, an instrument and a system for performing verification measurements and corrections of magnetic fields in magnets for Nuclear Magnetic Resonance imaging machines. According to the invention, test elements are used whereof Nuclear Magnetic Resonance images are detected. Then, these actually detected images are compared with the theoretical images which would be obtained in ideal conditions. The number, magnitude and position of correcting magnetic charges are determined from the differences between the actual image and the theoretical image. The invention is also directed to a specific test element and to a Nuclear Magnetic Resonance imaging machine.

Abstract: An apparatus for obtaining multiple spectra from a plurality of samples through the use of nuclear magnetic resonance (NMR) spectroscopy. A plurality of microcoils are coupled to and are in operable communication with an NMR spectrometer. The coils are operable in both a transmit mode and a receive mode to transmit RF energy to a sample being analyzed and to receive the return data for analysis by the NMR spectrometer. At least one switch is coupled to the plurality of coils and the NMR spectrometer. A controller for the NMR spectrometer is coupled to the switch and is used to control alternative activation of the coils for NMR data acquisition of multiple samples.

Abstract: A method and apparatus in which the limitation upon analysis caused by variation of the magnetic susceptibility of the solvent conveying a sample to an NMR spectrometer can be addressed. The solvent composition which is used to bring about elution of analyte from devices such as chromatography columns can be varied without causing a corresponding variation of the solvent composition used to transport the analyte to the NMR spectrometer. The decoupling is achieved by the summing into the chromatographic stream, post column, a solvent composition which is complementary to the instantaneous composition emerging from the column, such that the magnetic susceptibility of the summed streams remains constant.

Abstract: In a magnetic resonance tomography apparatus, and a pulse sequence for operating the apparatus, a radio frequency pulse, having a flip angle of &agr;/2 is emitted into a subject in a first pulse sequence section, by second and third pulse sequence sections in which a sequence of radio frequency pulses is emitted, each having a flip angle &agr; and a repetition time which is lower than the T1 and T2 relaxation times of the subject, the subject eventually reaching a steady state equilibrium condition after which the third pulse sequence section begins. In the third pulse sequence section, magnetic signals are read out from the subject with a phase coding, the phase coding being reset before the next radio frequency pulse in the sequence.

Abstract: Increasing RF transmission power, retuning the RF transmitter and receiver coils, and increasing RF reception gain, enable MR inspection of product in a container that presents a substantial portion of an electrically conductive barrier in transverse orientation to the exciting RF magnetic field.