Abstract: Embodiments of the present application provide a magnetic resonance system and a shimming method and an imaging method thereof. The shimming method comprises: performing a scout scan on a subject to be examined, and obtaining phase data of a plurality of slice positions; determining three-dimensional space static magnetic field information according to the phase data of the plurality of slice positions; and determining a shimming value of a slice in a region of interest according to the three-dimensional space static magnetic field information.

Abstract: An imaging method may include obtaining imaging data associated with a region of interest (ROI) of an object. The imaging data may correspond to a plurality of time-series images of the ROI. The imaging method may also include determining, based on the imaging data, a data set including a spatial basis and one or more temporal bases. The spatial basis may include spatial information of the imaging data. The one or more temporal bases may include temporal information of the imaging data. The imaging method may also include storing, in a storage medium, the spatial basis and the one or more temporal bases.

Abstract: A low-cost modular liquid nitrogen low-temperature multi-nuclear magnetic resonance probe includes a Dewar, a pluggable coil and a front-end gain amplifier. The Dewar includes a cylindrical sandwich chamber, the center of the cylindrical sandwich chamber constitutes a room-temperature chamber, a sandwich of the cylindrical sandwich chamber is divided into a vacuum chamber and a liquid nitrogen chamber by a liquid nitrogen vessel wall, the vacuum chamber is located between the room-temperature chamber and the liquid nitrogen chamber, the pluggable coil and the front-end gain amplifier are provided in the vacuum chamber, the pluggable coil comprises a coil portion and a pluggable base, the coil portion is in pluggable connection with the pluggable base, and the pluggable coil is connected with the front-end gain amplifier. The probe realizes the transmission of radio frequency pulses and the reception of magnetic resonance signals, and is applicable to whole-body imaging of a small animal.

Abstract: A method for discovering optimal algorithms is provided. The method comprises defining a starting condition for a program defining a number of program targets, wherein the program targets map program user-specified inputs to expected outputs, defining a number of program objectives, and defining a number of program constraints. An iterative optimization problem is then initialized to solve for the resulting program. A determination is made if defined termination conditions have been met according to the program targets and optimization objectives. Responsive to the defined termination conditions not being met an update to the program is selected by addition or subtraction of operations, the updated program is evaluated according to the program targets, the number of program objectives are evaluated, and the optimization problem is re-iterated. Responsive to the defined termination conditions being met, the program is reassembled into an instruction set.

Abstract: The present disclosure relates to magnetic resonance imaging (MRI) methods comprising (i) obtaining a baseline chemical exchange saturation transfer (CEST) MRI image of a patient, (ii) administering an effective amount of a non-nutritive sweetener to the patient, and (iii) obtaining one or more test CEST MRI image of the patient subsequent to the administering step (ii); wherein the step (i) and (iii) acquisition parameters are substantially the same. The non-nutritive sweetener may include a natural or artificial sugar alcohol, polyol, or combinations or derivatives thereof.

Abstract: The disclosure relates to a technique for providing an image of diagnostically relevant area of a jaw region of a patient by means of a magnetic resonance apparatus by capturing information about the jaw region of the patient, which comprises at least one reference to a position and/or an extent of the diagnostically relevant area of the jaw region. The technique also includes adjusting a parameter of a magnetic resonance measurement as a function of the captured information about the jaw region of the patient, carrying out the magnetic resonance measurement with the adjusted parameter, capturing image data of the jaw region of the patient, reconstructing an image of the diagnostically relevant area of the jaw region as a function of the captured image data, and providing the image of the diagnostically relevant area of the jaw region of the patient.

Abstract: The present application discloses a pluggable connecting buckle, including a male buckle and a female buckle. A first connecting rod is arranged on one end of the male buckle, and a decorative plate and a buckling rib are arranged on an other end. A buckling block is arranged on the buckling rib, and a corresponding engagement groove is arranged on the buckling rib. A second connecting rod and an accommodating cavity are respectively arranged on two ends of the female buckle. Two engagement assemblies are respectively arranged on two sides of the accommodating cavity. A limiting plate is arranged on the engagement assembly which includes a turning plate. An inclined engagement surface is arranged on the engagement groove, and an inverted hook plane is arranged on the turning end of the turning plate. The pluggable connecting buckle has a good anti-loosening effect, a long service life, and good user experience.

Abstract: A method for determining movement of an object to be imaged in a medical imaging method which includes at least one Magnetic Resonance Imaging, wherein the method comprises the following steps determining first coefficients of a mathematical transformation based on first navigator data of the object, wherein the first navigator data are recorded by a magnetic resonance tomograph (100) using a first spherical Lissajous navigator in the k-space with kr<0.2/cm, preferably kr<0.15/cm, and particularly preferably kr<0.1/cm, wherein kr represents the absolute value of the wave vector k.

Abstract: The invention relates to a method of MR imaging of an object (10). It is an object of the invention to enable MR imaging using radial acquisition with a reduced level of phase distortions and corresponding image artefacts. The method of the invention comprises the steps of: a) generating MR signals by subjecting the object to an imaging sequence comprising RF pulses and switched magnetic field gradients; b) acquiring the MR signals as radial k-space profiles, wherein pairs of spatially adjacent k-space profiles are acquired in opposite directions and wherein k-space profiles acquired in temporal proximity are close to each other in k-space; c) reconstructing an MR image from the acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

Abstract: Systems and methods are provided for determine the fat composition in an organ of interest using a non-invasive health measurement system. The non-invasive health measurement system may include an open magnet NMR apparatus. The NMR apparatus may measure NMR signals in a sensitive volume of a patient. The sensitive volume may coincide with an organ of interest, such as a liver. Systems and methods disclosed herein may provide for separation of the water contribution and the fat contribution to the measured NMR signal. Diffusion based separation, T2 based separation, and T1 based separation may each serve as different methods for separating the water and fat contributions to the signal. Separating the water and fat contributions to the single may allow for computation of a proton density fat fraction which may reflect the fat composition of the organ of interest.

Abstract: A method for determining the pore types of a core sample can include: determining a porosity of a core sample, wherein the core sample has a permeability of 10 mD or less; saturating the core sample with a NMR saturation fluid to achieve a saturated core sample; taking a NMR measurement of fluids in the saturated core sample; and deriving a volume for a pore type based on the porosity based on a correlation between the NMR measurement and a NMR signal to fluid volume calibration, wherein the pore type is selected from the group consisting of a nanopore, a micropore, a macropore, and any combination thereof.

Abstract: Devices, systems, and methods for enhancing MRI image quality and tracking accuracy in MR-guided treatment systems are described.

Abstract: A method for shaping an RF pulse for use with an MRI system includes shaping an RF pulse for use with an MRI system that uses an RF coil. The RF pulse is shaped to reduce changes in B1 amplitude and in an off-resonance effect with respect to Larmor frequency as a function of distance from the RF coil.

Abstract: A method is disclosed for recording medical images of the human body or that of an animal. The method includes scanning for acquiring data and signaling the start and/or end of a manual administration of a contrast medium in temporal relation to the scan for acquiring data.

Abstract: A grinder comprises a bearing track and a plurality of bearing elements such as ball bearings or roller bearings. Optionally, the bearing elements are protected from fouling or contamination from the material being ground, which can be, for example, herbs, spices, tobacco, or cannabis.

Abstract: The present application provides a system and method for using a nuclear magnetic resonance (NMR) system. The method includes performing a pulse sequence using the NMR system that spatially encodes NMR signal evolutions to be acquired from a subject using an aggregated radio-frequency (B1) field incoherence and resolving the NMR signal evolutions acquired from the subject using at least one of a dictionary of known magnetic resonance fingerprinting (MRF) signal evolutions to determine matches in the NMR signal evolutions to the known MRF signal evolutions or an optimization process. The method also includes generating at least two spatially-resolved measurements indicating quantitative tissue parameters of the subject in at least two locations.

Abstract: A method for determining the porosity of a core sample can include: saturating a core sample with a nuclear magnetic resonance (NMR) saturation fluid, wherein the core sample has a permeability of 100 milliDarcy (mD) or less, to achieve a saturated core sample; taking a NMR measurement of fluids in the saturated core sample; determining a porosity of the core sample based on a correlation between the NMR measurement and a NMR signal to fluid volume calibration.

Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —generating MR signals by subjecting the object to an imaging sequence, —acquiring MR signal profiles in a Cartesian k-space sampling scheme, wherein each MR signal profile is acquired in the presence of a temporally constant magnetic field gradient along a readout direction and a sinusoidally modulated magnetic field gradient along a phase encoding direction, and—reconstructing an MR image from the acquired MR signal profiles taking the modulation scheme of the magnetic field gradients into account. The invention proposes that the frequency of the sinusoidal modulation of the magnetic field gradient is varied during acquisition of each MR signal profile. Moreover, the invention relates to a MR device for carrying out this method as well as to a computer program to be run on a MR device.

Abstract: A computer-implemented method of performing deep learning based isocenter positioning includes acquiring a plurality of slabs covering an anatomical area of interest that comprises a patient's heart. For each slab, one or more deep learning models are used to determine a likelihood score for the slab indicating a probability that the slab includes at least a portion of the patient's heart. A center position of the patient's heart may then be determined based on the likelihood scores determined for the plurality of slabs.

Abstract: A magnetic resonance imaging (MRI) system with low-power miniaturization, a power supply system, and a power management system are provided. The MRI system includes: a permanent magnet using samarium-cobalt material, an MR console, a transmission RF chain, a receiving RF chain, gradient coils, gradient amplifiers, and a terminal device for user interactions. Each of above systems is a ultra-light and ultra-low-power ultra-low field brain MRI system for highly accessible healthcare applications.

Abstract: Methods of assessing or obtaining an indication of the presence of a cognitive disorder by analysing microstructural changes in regions of the brain are provided. The invention particularly relates to methods of assessing or obtaining an indication of the presence of types of dementia, for example Alzheimer's disease, by analysing changes in minicolumns in regions or layers of the cortex of the brain or of the whole brain.

Abstract: A method of performing multidimensional magnetic resonance imaging on a subject comprises collecting imaging data for a region of interest of the subject, the imaging data related to one or more spatially-varying parameters of the subject within the region of interest; collecting auxiliary data for the region of interest in the subject, the auxiliary data related to one or more time-varying parameters of the subject within the region of interest; linking the imaging data and the auxiliary data; and constructing an image tensor with one or more temporal dimensions based on at least a portion of the linked imaging data and at least a portion of the linked auxiliary data.

Abstract: A method for k-space registration is provided. The method of k-space registration includes receiving a first partial k-space dataset for an object and a second partial k-space dataset for the object, selecting the first partial k-space dataset as a reference, selecting feature for estimating a transformation matrix for transforming k-space data, estimating a transformation matrix based on the feature of entire or part of the first partial k-space dataset and the feature of the second partial k-space dataset corresponding to the entire or part of the first partial k-space dataset, correcting the second partial k-space dataset based on the transformation matrix, and obtaining the corrected second partial k-space dataset. The present method is further used for partial Fourier reconstruction.

Abstract: A peripheral nerve conduction diagnosis system that utilizes an electrostimulation device having dry elastomer electrodes and a distance measuring device that allow a user to move the electrostimulation device along the skin of a patient while in constant contact with the skin and measure the distance moved.

Abstract: The present invention relates to a method based on proton NMR technique to differentiate genuine and spurious Hand-rub formulations. This method identifies and estimates all four components present in WHO-recommended Hand-rub formulations. Further, this method also identifies the presence of non-recommended/additional components present in WHO-recommended Hand-rub formulations. The method described in this invention utilizes experimental parameters and derived equations to quantify all four components in just fifteen minutes without using any organic solvents.

Abstract: Improved magnetic resonance imaging systems, methods and software are described including a low field strength main magnet, a gradient coil assembly, an RF coil system, and a control system configured for the acquisition and processing of magnetic resonance imaging data from a patient while utilizing a sparse sampling imaging technique.

Abstract: An approach to estimate noise, Rician signal bias and true signal in magnitude signal data obtained with magnetic resonance imaging. The method uses multiple measurements at different scan parameter settings, also referred to as weightings, and an iterative algorithm to estimate noise, expected signal and associated Rician signal bias. Measurements at all measured weighting levels contribute to the ultimate estimation of the bias-free signal decay function. Therefore, of the so processed magnetic resonance image data, weighted signals can be computed at arbitrary weighting levels and with considerably better signal-to-noise ratio than the originally obtained data at corresponding weightings. Bias-free weighted image data at desired weighting levels, maps of the decay function fit parameters, or maps of a combination of such decay function parameters can be used for rapid and highly sensitive tissue characterization.

Abstract: A method a for acquiring magnetic resonance data of an object under examination by means of a magnetic resonance system comprises: in an excitation phase, applying an RF excitation pulse; in a wait phase following the excitation phase, applying at least one first RF refocusing pulse after the applied RF excitation pulse according to a first echo spacing; in an acquisition phase following the wait phase, applying at least two further RF refocusing pulses to generate echo signals according to a second echo spacing, wherein the second echo spacing is smaller than the first echo spacing; and reading out the echo signals generated in the acquisition phase as magnetic resonance data from which image data can be reconstructed, wherein in the wait phase at least two spoiler gradients are switched in the readout direction.

Abstract: An MRI phantom having an MRI compatible temperature measurement device having an MRI compatible body containing an MRI compatible fluid, wherein the device senses accurate temperature measurement within an MR Scanner environment using image processing of the contrast in signal between the areas of the image around the device and the fluid contained within the body of the device. The MRI Phantom may further include an internal expansion bladder device accomodating internal changes in pressure within the phantom, wherein the internal expansion bladder device includes frames supporting a pair of spaced membranes defining a chamber filled with a compressible gas.

Abstract: A method of magnetic resonance (MR) imaging includes a phantom that is inexpensive to produce and enables simple, practical and fast assessment of image sharpness, in particular for checking image quality of MR imaging with spiral acquisition. The method includes subjecting a phantom, which comprises a volume filled with a bulk of granules of solid material surrounded by a liquid, to an imaging sequence, acquiring MR signals from the phantom, reconstructing an MR image from the acquired MR signals, and deriving a measure of the local image sharpness in two or more different image regions from the MR image, wherein each image region is a representation of a part of the phantom volume.

Abstract: The disclosure relates to a magnetic resonance tomography scanner and to a method for operating the magnetic resonance tomography scanner. The method includes determining a B0 field map. The method further includes determining an excitation of the nuclear spins to be achieved and a spectrally selective excitation pulse for transmission by a transmitter by way of an antenna as a function of the B0 field map. In the method, the excitation pulse is configured here to generate the excitation of the nuclear spins to be achieved in the patient. The excitation pulse is then output by way of the antenna.

Abstract: A method for denoising magnetic resonance images and data is disclosed herein. An example method includes receiving a series of MRF images from a scanning device; identifying one or more subsets of voxels for the series of MRF images; generating one or more sets of eigenvectors, each set of the one or more sets of eigenvectors corresponding to one of the one or more subsets of voxels, and each eigenvector of the one or more sets of eigenvectors having a corresponding eigenvalue; applying a noise distribution model to each of the eigenvalues; identifying a subset of the eigenvalues as corresponding to noise based on the noise distribution model; and reconstructing the series of MRF images without the subset of eigenvalues identified as corresponding to noise.

Abstract: Methods, computer-readable storage media and systems are described for constructing a three-dimensional electronic library of simulated decays of the diffusion-weighted 1H2O MR signal in b-space. Methods, computer-readable media, and systems are described for preparing a parametric tissue map for tissue in a subject. Computer readable media, having an electronic library of simulated decays of the diffusion-weighted 1H2O signal in b-space and method of using such a library.

Abstract: A method for measuring oil-water distribution using DNP-MRI, comprising adding a free radical for DNP enhanced NMR signal of a water phase or an oil phase in a sample containing oil and water; performing an MRI experiment on the sample, and collecting an MRI image of the sample without DNP enhancement; applying microwave excitation for DNP-MRI experiment under the same MRI experiment condition as step 2, and collecting an MRI image of the sample after DNP enhancement; and comparing the MRI image after DNP enhancement with the MRI image without DNP enhancement. In the MRI image with DNP enhancement, an area with enhanced MRI signal intensity is a selectively enhanced fluid phase distribution area, and an area without obviously changed MRI signal intensity is a non-selectively enhanced fluid phase distribution area. The method is simple, convenient to operate, short in measurement time, and high in measurement efficiency.

Abstract: Apparatus and methods for the detection of proteins in biological fluids such as urine using a label-free assay is described. Specific proteins are detected by their binding to highly specific capture reagents such as SOMAmers that are attached to the surface of a substrate. Changes to these capture reagents and their local environment upon protein binding modify the behavior of color centers (e.g., fluorescence, ionization state, spin state, etc.) embedded in the substrate beneath the bound capture reagents. These changes can be read out, for example, optically or electrically, for an individual color center or as an average response of many color centers.

Abstract: Methods for reconstructing images from undersampled k-space data using a machine learning approach to learn non-linear mapping functions from acquired k-space lines to generate unacquired target points across multiple coils are described.

Abstract: A system and method for correcting phase shift in echo images are provided. The method may include one or more of the following operations. A plurality of echo images may be obtained. Homogeneous pixels in the plurality of echo images may be identified. A vector corresponding to each of at least some of the identified homogeneous pixels may be determined. A vector of a homogenous pixel includes a phase element and an amplitude element. A first complex linear model of phase shift may be determined based at least in part on the determined vectors. Phase shift of at least one of the plurality of echo images may be corrected based on the first complex linear model.

Abstract: In a method for providing setting parameter sets for at least one measuring protocol described by protocol parameters for acquiring magnetic resonance data with a magnetic resonance facility, setting parameter set is determined for each of at least two temperature status categories of the magnetic resonance facility using a temperature model describing a development of a temperature status of at least one component of the magnetic resonance facility. The method also includes preventing overheating of the at least one component due to the measurement with the measuring protocol being repeated a maximum number of times for a specified number of repetitions.

Abstract: Techniques regarding the development and/or analysis of one or more quantum computing programs are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a circuit component, operatively coupled to the processor, that can create a quantum computing program over a period of time. The computer executable components can also comprise a visualization component, operatively coupled to the processor, that can generates a quantum state visualization that depicts a characterization of the quantum computing program over the period of time.

Abstract: In vivo methods for non-invasively imaging (or measuring without spatial localization) of neuro-electro-magnetic oscillations are achieved by a pulse sequence of radio frequency (RF) irradiation and magnetic field gradients. These RF and gradient pulses create an intermolecular zero-quantum coherence (iZQC), the frequency of which is: 1) controlled by one or more magnetic field gradients; and 2) made to match the frequency of the targeted neuro-electro-magnetic oscillation.

Abstract: Techniques for compensating magnetic resonance imaging (MRI) data for artefacts caused by motion of a subject being imaged. The techniques include obtaining spatial frequency data obtained by using a magnetic resonance imaging (MRI) system to perform MRI on a patient, the spatial frequency data including first spatial frequency data and second spatial frequency data; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; determining a residual spatial phase; correcting, using the transformation, second spatial frequency data and the residual spatial phase, to obtain corrected second spatial frequency data and a corrected residual spatial phase; and generating a magnetic resonance (MR) image using the corrected second spatial frequency data and the corrected residual spatial phase.

Abstract: In methods for simulating the evolution of a real-world quantum system over time, a state-preparation sequence of quantum gates is applied to a qubit register of a quantum computer. The state-preparation sequence is configured to prepare in the qubit register an initial model state representing an initial state of the real-world quantum system. A Hamiltonian operator for the real-world quantum system is received and used in the example method. The Hamiltonian operator represents two-body potential-energy interactions in a factorized form comprising at least one Majorana operator. A time-evolution-operator sequence of quantum gates comprising a block-encoded form of the Hamiltonian operator is now applied to the qubit register of the quantum computer, yielding a changed model state that represents a time-evolved state of the real-world quantum system. A measurement operation is applied subsequently to the qubit register.

Abstract: A method, apparatus and components thereof enable selective or differentiated manipulation of at least one of a plurality of particles located in a region of space via magnetic field generation and variation.

Abstract: Disclosed is a method for generating a time-dependent magnetic field gradient in diffusion weighted magnetic resonance imaging G(t)=[Gx(t)Gy(t)Gz(t)]T, which is asymmetric in time with respect to a refocusing pulse, by meeting one or more of the requirements: A=?0TEh(t)G(t)G(t)Tdt is zero, where TE is an echo time and h(t) is a function of time which is positive during an interval prior to the refocusing pulse and negative during a time interval after the refocusing pulse); minimize A or m=(Tr[AA])1/2 where A=?P1G(t)G(t)Tdt??P2G(t)G(t)Tdt where P1 and P2 represent time intervals prior to and subsequent to the refocusing pulse; m is smaller than a threshold value. an attenuation factor AF p = exp ? ( - t T ? 2 * ) due to T2* relaxation is one. Signal attenuation due to concomitant field gradients, regardless of the shape or orientation of the diffusion encoding b-tensor and the location of signal is hereby minimized.

Abstract: Devices for determining a state of a magnetic field-generating article are provided. In various embodiments, a device comprises: a single crystal diamond having a plurality of NV centers, the single crystal diamond configured to be disposed adjacent to a magnetic field-generating article, and configured to generate a fluorescent signal in response to being illuminated by a light source; a coherent light source configured to generate a light beam directed at the single crystal diamond; a microwave (MW) radiation source configured to irradiate the single crystal diamond with a MW signal; a magnetic field source configured to apply a bias magnetic field to the single crystal diamond; a photosensor configured to collect the fluorescent signal generated by the single crystal diamond; and a computing node operatively coupled to each of the coherent light source, the MW radiation source, the magnetic field source, and the photosensor.

Abstract: The present disclosure relates to techniques for the selection of one or more measuring coils in magnetic resonance imaging. Herein, account can be taken of a preselection in the selection of the one or more measuring coils from a plurality of candidate coils.

Abstract: In a method (100 to 208) in which hyperpolarizable tracer molecules (20, 88 to 98) are hydrogenated and then optionally also hyperpolarized for magnetic resonance imaging, it is provided that, in a first method step (104, 202), a hydrogen solution (10, 12, 4) having a saturation factor of at least 50% be prepared and that the hydrogenation reaction (186 to 190, 206) not be triggered until a subsequent, second method step (106, 204). An apparatus (1) with which the method of the invention (100 to 208) is executable is also provided.

Abstract: The present invention relates to a method of calculating a proton density fat fraction, PDFF, from a water and fat separated magnetic resonance imaging, MRI, based on fat-referenced lipid quantification in a region of interest (ROI) and using determination of a reference tissue. The method comprises the step of determining: F·?f/R, wherein F is the fat signal in the ROI provided from the MRI, ?f is a function providing a ratio between T1 saturation values of the fat signals in the reference tissue and in the ROI; and R is a representation of the sum of fat and water signals on an intensity scale where the saturation of each of the fat and water signals equals the saturation of fat in the reference tissue.

Abstract: In MRI, upon simultaneously generating computed images of multiple parameters, imaging time is efficiently reduced while preventing decrease in spatial resolution and SN ratio as much as possible. A plurality of original images is reconstructed from nuclear magnetic resonance signals acquired under various imaging conditions, and a computed image is obtained by calculation performed among the plurality of original images. The various imaging conditions include an imaging condition that a repetition time of an imaging sequence is different from one another, and upon imaging, the number of phase encoding steps is made smaller when the repetition time is long. An image is reconstructed in such a manner that a matrix size of the image obtained when the number of phase encoding steps is small is made equal to the matrix size of the image obtained when the number of phase encoding steps is large.

Abstract: A sample chamber holder for MAS-NMR capable of operating at both low and high pressures. In one example the sample chamber holder is made up of a sample holder body defining a sample chamber therein, a connector configured to operatively statically hold an in situ rotor within the sample chamber; a coupler configured to operatively connect the sampler holder body to a magnetically coupled rotation member. The magnetically coupled rotation member is configured to engage and rotate a sealing cap from an NMR rotor in such a way so as to allow an NMR cap to be alternatively opened or sealed in-situ while the NMR rotor remains statically positioned in an NMR device.