Using A Nuclear Resonance Spectrometer System Patents (Class 324/307)
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Patent number: 12132456Abstract: A noise detecting circuit including an amplifier circuit amplifying an input signal indicating a noise level of a circuit to be detected and output an amplified signal; a filtering circuit receiving and filtering the amplified signal and output a filtered signal; and a comparing circuit receiving and compare the filtered signal to a reference voltage and output an output signal; wherein the filtering circuit includes: an output terminal; and a first filter selectively coupled to the output terminal, including: a sub-output terminal; a switch selectively coupling the sub-output terminal to the output terminal; a resistor, wherein a terminal of the resistor is coupled to the amplifier circuit and another terminal of the resistor is coupled to the sub-output terminal; and a capacitor, wherein a terminal of the capacitor is coupled to the sub-output terminal and another terminal of the capacitor is coupled to a reference voltage source.Type: GrantFiled: July 24, 2023Date of Patent: October 29, 2024Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.Inventors: Bei-Shing Lien, Jaw-Juinn Horng
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System and method for oscillatory eddy current correction for diffusion-weighted echo-planar imaging
Patent number: 12123933Abstract: A method for correcting diffusion-weighted echo-planar imaging data (DW-EPI) includes obtaining a first reference scan with no diffusion gradients applied, a second reference scan with a diffusion gradient applied only along a frequency direction, a third reference scan with the diffusion gradient applied only along a phase direction, and a fourth reference scan with the diffusion gradient applied only along a slice direction acquired utilizing an MRI scanner, wherein the reference scans lack phase encoding. The method includes obtaining DW-EPI data acquired utilizing the MRI scanner, wherein the DW-EPI data includes phase errors due to oscillatory eddy currents causing time-varying B0 shift. The method includes generating a phase correction factor based on the reference scans and correcting the phase errors due to the oscillatory eddy currents in the DW-EPI data independent of diffusion gradient direction utilizing the phase correction factor to generate corrected DW-EPI data.Type: GrantFiled: December 12, 2022Date of Patent: October 22, 2024Assignee: GE Precision Healthcare LLCInventors: Hua Li, Lei Gao, Gaohong Wu -
Patent number: 12105016Abstract: Some embodiments of the present disclosure relate to systems and methods including generating, by infrared spectroscopy, spectra data identifying quantities and associated wavelengths of radiation absorption for each of a plurality of wine samples as determined by the infrared spectroscopy; converting the spectra data for each wine sample to a set of discretized data; transforming the discretized data into a visual image representation of each respective wine sample, the visual image representation of each wine sample being an optically recognizable representation of the corresponding converted set of discretized data; and storing a record including the visual image representation of each wine sample in a memory.Type: GrantFiled: January 31, 2022Date of Patent: October 1, 2024Assignee: PENROSE HILLInventors: Matthew K. Martz, Philip James, Erik Steigler
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Patent number: 12106897Abstract: The invention relates to a superconducting magnet coil system comprising a first electrical mesh (M1) and a second electrical mesh (M2), which are interconnected in series with one another, wherein the first electrical mesh (M1) comprises in a first path an HTS (high temperature superconductor) coil section (A0) and, in series therewith, a first main coil section (A1) and in a second path a quench protection element (Q1), which bridges the series connection of HTS coil section (A0) and first main coil section (A1). The first main coil section (A1) comprises a conductor comprising superconducting filaments in a matrix. The second electrical mesh (M2) comprises a neighbouring main coil section (A3) comprising a conductor comprising superconducting filaments in a matrix.Type: GrantFiled: July 3, 2019Date of Patent: October 1, 2024Inventors: Wolfgang Frantz, Rafael Caminada, Gerald Neuberth
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Patent number: 12078700Abstract: Spin resonance spectroscopy and/or imaging is achieved using a system that combines longitudinal (e.g., along the z-axis) detection with a modulated fictitious field generated by a transverse plane (e.g., xy-plane) RF field. Based on z-axis detection of magnetization polarized by this fictitious field as it is modulated (e.g., modulated on and off, or otherwise), spin resonance signals (e.g., EPR, NMR) are measurable with high isolation simultaneous transmit and receive capability. Additionally or alternatively, spin relaxation times can be measured using the described systems.Type: GrantFiled: March 8, 2022Date of Patent: September 3, 2024Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Xueyan Tang, Michael Garwood, Steven Suddarth
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Patent number: 12078704Abstract: The disclosure relates to techniques for executing a measurement sequence in an MRI system, wherein a plurality of measurement subsequences are to be executed within the measurement sequence, each measurement subsequence comprising measurement blocks to be interleaved on a time scale of the MRI system. For each measurement subsequence a respective time value defines when the next measurement block is to be executed on a global time scale by the MRI system. The measurement subsequences are stored in a container ordered according to their respective time values, and the first measurement subsequence is accessed from the subsequence list for execution by the MRI system in run-time.Type: GrantFiled: March 11, 2021Date of Patent: September 3, 2024Assignee: Seimens Healthineers AGInventor: Thomas Kluge
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Patent number: 12056876Abstract: A method (400) including: determining (702) a registration function [705, Niirf(T1)] for the particular brain in a coordinate space, determining (706) a registered atlas [708, Ard(T1)] from the registration function and an HCP-MMP1 Atlas (102) containing a standard parcellation scheme, performing (310, 619) diffusion tractography to determine a set [621, DTIp(DTI)] of brain tractography images of the particular brain, for a voxel in a particular parcellation in the registered atlas, determining (1105, 1120) voxel level tractography vectors [1123, Vje, Vjn] showing connectivity of the voxel with voxels in other parcellations, classifying (1124) the voxel based on the probability of the voxel being part of the particular parcellation, and repeating (413) the determining of the voxel level tractography vectors and the classifying of the voxels for parcellations of the HCP-MMP1 Atlas to form a personalised brain atlas [1131, PBs Atlas] containing an adjusted parcellation scheme reflecting the particular brain (BbType: GrantFiled: June 9, 2021Date of Patent: August 6, 2024Assignee: Omniscient Neurotechnology Pty LimitedInventors: Michael Edward Sughrue, Stephane Philippe Doyen, Charles Teo
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Patent number: 12046462Abstract: After collecting mass spectrometry data for each of a large number of measurement points in the two-dimensional region on the sample with the imaging mass spectrometry unit, the user inputs the target compound whose two-dimensional distribution is desired to be observed from the input unit. The image display instruction reception unit obtains the m/z range for data integration from the precise m/z value and the allowable width of m/z for each target compound. The mass-to-charge ratio range overlap determination unit determines the presence or absence of overlap between the m/z ranges of a plurality of compounds, and if there is an overlap, the overlap determination result processing unit creates and displays on the screen of the display unit a list of compounds whose m/z ranges overlap, for example. This urges the user to review the compounds and allowable values.Type: GrantFiled: May 30, 2018Date of Patent: July 23, 2024Assignee: SHIMADZU CORPORATIONInventor: Tomonori Oshikawa
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Patent number: 12029544Abstract: The disclosure relates to techniques for acquiring measured data that has been recorded simultaneously via a magnetic resonance facility from at least two slices from an examination object comprising at least two different spin types. The techniques includes selecting a desired simultaneous recording of measured data from at least two slices in which during recording phases that generate field of view shifts have been imprinted, selecting a compensation factor to compensate for interference signals caused by the different spin types, determining a compensation phase for the phases to be imprinted in the desired recording as a function of the compensation factor, and carrying out the desired recording of measured data and/or reconstruction of image data from the measured data by applying the compensation phase that has been determined to the respective phases to be imprinted.Type: GrantFiled: March 30, 2022Date of Patent: July 9, 2024Assignee: Siemens Healthineers AGInventors: Flavio Carinci, Mario Zeller, Dominik Paul
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Patent number: 11986674Abstract: The present disclosure relates to a system and a method. The system may include a magnetic resonance imaging (MRI) apparatus configured to acquire MRI data with respect to a region of interest (ROI) and a therapeutic apparatus configured to apply therapeutic radiation to at least one portion of the ROI. The MRI apparatus may include a plurality of main magnetic coils arranged coaxially along an axis, a plurality of shielding magnetic coils arranged coaxially along the axis, and a cryostat in which the plurality of main magnetic coils and the plurality of shielding magnetic coils are arranged.Type: GrantFiled: March 29, 2021Date of Patent: May 21, 2024Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Cheng Ni, Xingen Yu, Yanfang Liu, Jingjie Zhou, Jianfeng Liu, Li Wang, Peng Wang, Yangyang Zhang
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Patent number: 11972066Abstract: An information handling system mouse has a variable speed scroll wheel with magnetic tactile response. A ferromagnetic wheel coupled to the scroll wheel and having spikes and valleys interacts with a magnetic field of magnet as the scroll wheel rotates to resist rotation in variable amounts. The magnetic field is selectively removed to reduce the tactile response, such as by disengaging a magnet from a magnetic focus lens that directs the magnetic field, moving an opposing magnet into contact with the magnetic focus lens that cancels the magnetic field and moving the magnet away from the ferromagnetic wheel.Type: GrantFiled: July 28, 2022Date of Patent: April 30, 2024Assignee: Dell Products L.P.Inventors: Peng Lip Goh, Deeder M. Aurongzeb
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Patent number: 11965945Abstract: Embodiments of the present application provide a magnetic resonance system and a shimming method and an imaging method thereof. The shimming method comprises: performing a scout scan on a subject to be examined, and obtaining phase data of a plurality of slice positions; determining three-dimensional space static magnetic field information according to the phase data of the plurality of slice positions; and determining a shimming value of a slice in a region of interest according to the three-dimensional space static magnetic field information.Type: GrantFiled: August 23, 2022Date of Patent: April 23, 2024Assignee: GE Precision Healthcare LLCInventors: Yaan Ge, Liyuan Jin, Qingyu Dai, Kun Wang, Qilin Lu
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Patent number: 11963752Abstract: An imaging method may include obtaining imaging data associated with a region of interest (ROI) of an object. The imaging data may correspond to a plurality of time-series images of the ROI. The imaging method may also include determining, based on the imaging data, a data set including a spatial basis and one or more temporal bases. The spatial basis may include spatial information of the imaging data. The one or more temporal bases may include temporal information of the imaging data. The imaging method may also include storing, in a storage medium, the spatial basis and the one or more temporal bases.Type: GrantFiled: February 21, 2020Date of Patent: April 23, 2024Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Jingyuan Lyu, Qi Liu, Zhongqi Zhang, Jian Xu
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Patent number: 11959982Abstract: A low-cost modular liquid nitrogen low-temperature multi-nuclear magnetic resonance probe includes a Dewar, a pluggable coil and a front-end gain amplifier. The Dewar includes a cylindrical sandwich chamber, the center of the cylindrical sandwich chamber constitutes a room-temperature chamber, a sandwich of the cylindrical sandwich chamber is divided into a vacuum chamber and a liquid nitrogen chamber by a liquid nitrogen vessel wall, the vacuum chamber is located between the room-temperature chamber and the liquid nitrogen chamber, the pluggable coil and the front-end gain amplifier are provided in the vacuum chamber, the pluggable coil comprises a coil portion and a pluggable base, the coil portion is in pluggable connection with the pluggable base, and the pluggable coil is connected with the front-end gain amplifier. The probe realizes the transmission of radio frequency pulses and the reception of magnetic resonance signals, and is applicable to whole-body imaging of a small animal.Type: GrantFiled: November 10, 2021Date of Patent: April 16, 2024Assignee: INNOVATION ACADEMY FOR PRECISION MEASUREMENT SCIENCE AND TECHNOLOGY, CASInventors: Zhi Zhang, Qingjia Bao, Chaoyang Liu, Xinjie Liu, Fang Chen, Jiaxin Wang, Xin Cheng, Maili Liu
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Patent number: 11960859Abstract: A method for discovering optimal algorithms is provided. The method comprises defining a starting condition for a program defining a number of program targets, wherein the program targets map program user-specified inputs to expected outputs, defining a number of program objectives, and defining a number of program constraints. An iterative optimization problem is then initialized to solve for the resulting program. A determination is made if defined termination conditions have been met according to the program targets and optimization objectives. Responsive to the defined termination conditions not being met an update to the program is selected by addition or subtraction of operations, the updated program is evaluated according to the program targets, the number of program objectives are evaluated, and the optimization problem is re-iterated. Responsive to the defined termination conditions being met, the program is reassembled into an instruction set.Type: GrantFiled: November 12, 2021Date of Patent: April 16, 2024Assignee: The Boeing CompanyInventor: Richard Joel Thompson
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Patent number: 11938200Abstract: The present disclosure relates to magnetic resonance imaging (MRI) methods comprising (i) obtaining a baseline chemical exchange saturation transfer (CEST) MRI image of a patient, (ii) administering an effective amount of a non-nutritive sweetener to the patient, and (iii) obtaining one or more test CEST MRI image of the patient subsequent to the administering step (ii); wherein the step (i) and (iii) acquisition parameters are substantially the same. The non-nutritive sweetener may include a natural or artificial sugar alcohol, polyol, or combinations or derivatives thereof.Type: GrantFiled: February 3, 2017Date of Patent: March 26, 2024Assignees: The Trustees of the University of Pennsylvania, Sidra MedicineInventors: Ravinder Reddy, Mohammad Haris, Hari Hariharan, Puneet Bagga, Francesco M. Marincola, Mitchell D. Schnall
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Patent number: 11940518Abstract: The disclosure relates to a technique for providing an image of diagnostically relevant area of a jaw region of a patient by means of a magnetic resonance apparatus by capturing information about the jaw region of the patient, which comprises at least one reference to a position and/or an extent of the diagnostically relevant area of the jaw region. The technique also includes adjusting a parameter of a magnetic resonance measurement as a function of the captured information about the jaw region of the patient, carrying out the magnetic resonance measurement with the adjusted parameter, capturing image data of the jaw region of the patient, reconstructing an image of the diagnostically relevant area of the jaw region as a function of the captured image data, and providing the image of the diagnostically relevant area of the jaw region of the patient.Type: GrantFiled: March 25, 2022Date of Patent: March 26, 2024Assignee: Siemens Healthineers AGInventors: Andreas Greiser, Carmel Hayes, Mario Zeller
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Patent number: 11930894Abstract: The present application discloses a pluggable connecting buckle, including a male buckle and a female buckle. A first connecting rod is arranged on one end of the male buckle, and a decorative plate and a buckling rib are arranged on an other end. A buckling block is arranged on the buckling rib, and a corresponding engagement groove is arranged on the buckling rib. A second connecting rod and an accommodating cavity are respectively arranged on two ends of the female buckle. Two engagement assemblies are respectively arranged on two sides of the accommodating cavity. A limiting plate is arranged on the engagement assembly which includes a turning plate. An inclined engagement surface is arranged on the engagement groove, and an inverted hook plane is arranged on the turning end of the turning plate. The pluggable connecting buckle has a good anti-loosening effect, a long service life, and good user experience.Type: GrantFiled: February 16, 2023Date of Patent: March 19, 2024Assignee: Foshan Tuorun Precision Hardware Technology Co., LtdInventor: Maoyang Gao
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Patent number: 11927660Abstract: A method for determining movement of an object to be imaged in a medical imaging method which includes at least one Magnetic Resonance Imaging, wherein the method comprises the following steps determining first coefficients of a mathematical transformation based on first navigator data of the object, wherein the first navigator data are recorded by a magnetic resonance tomograph (100) using a first spherical Lissajous navigator in the k-space with kr<0.2/cm, preferably kr<0.15/cm, and particularly preferably kr<0.1/cm, wherein kr represents the absolute value of the wave vector k.Type: GrantFiled: May 22, 2019Date of Patent: March 12, 2024Assignee: FORSCHUNGSZENTRUM JÜLICH GMBHInventors: Richard Buschbeck, Nadim Joni Shah
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Patent number: 11914016Abstract: The invention relates to a method of MR imaging of an object (10). It is an object of the invention to enable MR imaging using radial acquisition with a reduced level of phase distortions and corresponding image artefacts. The method of the invention comprises the steps of: a) generating MR signals by subjecting the object to an imaging sequence comprising RF pulses and switched magnetic field gradients; b) acquiring the MR signals as radial k-space profiles, wherein pairs of spatially adjacent k-space profiles are acquired in opposite directions and wherein k-space profiles acquired in temporal proximity are close to each other in k-space; c) reconstructing an MR image from the acquired MR signals. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).Type: GrantFiled: May 28, 2020Date of Patent: February 27, 2024Assignee: Koninklijke Philips N.V.Inventors: Guruprasad Krishnamoorthy, Gabriele Marianne Beck
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Patent number: 11896392Abstract: Systems and methods are provided for determine the fat composition in an organ of interest using a non-invasive health measurement system. The non-invasive health measurement system may include an open magnet NMR apparatus. The NMR apparatus may measure NMR signals in a sensitive volume of a patient. The sensitive volume may coincide with an organ of interest, such as a liver. Systems and methods disclosed herein may provide for separation of the water contribution and the fat contribution to the measured NMR signal. Diffusion based separation, T2 based separation, and T1 based separation may each serve as different methods for separating the water and fat contributions to the signal. Separating the water and fat contributions to the single may allow for computation of a proton density fat fraction which may reflect the fat composition of the organ of interest.Type: GrantFiled: March 10, 2022Date of Patent: February 13, 2024Assignee: Livivos Inc.Inventors: Pablo Jose Prado, Alejandro Bussandri
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Patent number: 11898976Abstract: A method for determining the pore types of a core sample can include: determining a porosity of a core sample, wherein the core sample has a permeability of 10 mD or less; saturating the core sample with a NMR saturation fluid to achieve a saturated core sample; taking a NMR measurement of fluids in the saturated core sample; and deriving a volume for a pore type based on the porosity based on a correlation between the NMR measurement and a NMR signal to fluid volume calibration, wherein the pore type is selected from the group consisting of a nanopore, a micropore, a macropore, and any combination thereof.Type: GrantFiled: March 19, 2020Date of Patent: February 13, 2024Assignee: ExxonMobil Technology and Engineering CompanyInventors: Pavel Kortunov, Hubert E. King, Harry W. Deckman
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Patent number: 11878188Abstract: Devices, systems, and methods for enhancing MRI image quality and tracking accuracy in MR-guided treatment systems are described.Type: GrantFiled: May 3, 2022Date of Patent: January 23, 2024Assignee: Washington UniversityInventors: H. Michael Gach, Austen Curcuru, Taeho Kim, Umberto Villa
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Patent number: 11874347Abstract: A method for shaping an RF pulse for use with an MRI system includes shaping an RF pulse for use with an MRI system that uses an RF coil. The RF pulse is shaped to reduce changes in B1 amplitude and in an off-resonance effect with respect to Larmor frequency as a function of distance from the RF coil.Type: GrantFiled: March 17, 2021Date of Patent: January 16, 2024Assignee: Clear-Cut Medical Ltd.Inventors: Saul Stokar, Tal Bareket, Zachi Peles
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Patent number: 11857356Abstract: A method is disclosed for recording medical images of the human body or that of an animal. The method includes scanning for acquiring data and signaling the start and/or end of a manual administration of a contrast medium in temporal relation to the scan for acquiring data.Type: GrantFiled: February 6, 2015Date of Patent: January 2, 2024Assignee: SIEMENS HEALTHCARE GMBHInventors: Johannes Georg Korporaal, Rainer Raupach
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Patent number: 11849885Abstract: A grinder comprises a bearing track and a plurality of bearing elements such as ball bearings or roller bearings. Optionally, the bearing elements are protected from fouling or contamination from the material being ground, which can be, for example, herbs, spices, tobacco, or cannabis.Type: GrantFiled: January 24, 2020Date of Patent: December 26, 2023Inventor: Amit Gorodetzer
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Patent number: 11841413Abstract: The present application provides a system and method for using a nuclear magnetic resonance (NMR) system. The method includes performing a pulse sequence using the NMR system that spatially encodes NMR signal evolutions to be acquired from a subject using an aggregated radio-frequency (B1) field incoherence and resolving the NMR signal evolutions acquired from the subject using at least one of a dictionary of known magnetic resonance fingerprinting (MRF) signal evolutions to determine matches in the NMR signal evolutions to the known MRF signal evolutions or an optimization process. The method also includes generating at least two spatially-resolved measurements indicating quantitative tissue parameters of the subject in at least two locations.Type: GrantFiled: December 30, 2020Date of Patent: December 12, 2023Assignees: Case Western Reserve University, Vanderbilt UniversityInventors: Mark A. Griswold, William A. Grissom
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Patent number: 11815481Abstract: A method for determining the porosity of a core sample can include: saturating a core sample with a nuclear magnetic resonance (NMR) saturation fluid, wherein the core sample has a permeability of 100 milliDarcy (mD) or less, to achieve a saturated core sample; taking a NMR measurement of fluids in the saturated core sample; determining a porosity of the core sample based on a correlation between the NMR measurement and a NMR signal to fluid volume calibration.Type: GrantFiled: March 19, 2020Date of Patent: November 14, 2023Assignee: ExxonMobil Technology and Engineering CompanyInventors: Hubert E. King, Pavel Kortunov, Harry W. Deckman, Shreerang S. Chhatre, Hemantkumar R. Sahoo, Antonio S. Buono
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Patent number: 11815577Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). The method comprises the steps of: —generating MR signals by subjecting the object to an imaging sequence, —acquiring MR signal profiles in a Cartesian k-space sampling scheme, wherein each MR signal profile is acquired in the presence of a temporally constant magnetic field gradient along a readout direction and a sinusoidally modulated magnetic field gradient along a phase encoding direction, and—reconstructing an MR image from the acquired MR signal profiles taking the modulation scheme of the magnetic field gradients into account. The invention proposes that the frequency of the sinusoidal modulation of the magnetic field gradient is varied during acquisition of each MR signal profile. Moreover, the invention relates to a MR device for carrying out this method as well as to a computer program to be run on a MR device.Type: GrantFiled: February 18, 2020Date of Patent: November 14, 2023Assignee: Koninklijke Philips N.V.Inventors: Zechen Zhou, Peter Bornert
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Patent number: 11802925Abstract: A magnetic resonance imaging (MRI) system with low-power miniaturization, a power supply system, and a power management system are provided. The MRI system includes: a permanent magnet using samarium-cobalt material, an MR console, a transmission RF chain, a receiving RF chain, gradient coils, gradient amplifiers, and a terminal device for user interactions. Each of above systems is a ultra-light and ultra-low-power ultra-low field brain MRI system for highly accessible healthcare applications.Type: GrantFiled: October 29, 2021Date of Patent: October 31, 2023Assignee: CHENGDU YIJIAN MEDICAL TECHNOLOGY CO., LTDInventors: Ruixing Zhu, Zhizun Zhang, Hangxuan Li
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Patent number: 11800978Abstract: A computer-implemented method of performing deep learning based isocenter positioning includes acquiring a plurality of slabs covering an anatomical area of interest that comprises a patient's heart. For each slab, one or more deep learning models are used to determine a likelihood score for the slab indicating a probability that the slab includes at least a portion of the patient's heart. A center position of the patient's heart may then be determined based on the likelihood scores determined for the plurality of slabs.Type: GrantFiled: July 5, 2017Date of Patent: October 31, 2023Assignee: Siemens Healthcare GmbHInventors: Xiaoguang Lu, Carmel Hayes
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Patent number: 11796617Abstract: A method for k-space registration is provided. The method of k-space registration includes receiving a first partial k-space dataset for an object and a second partial k-space dataset for the object, selecting the first partial k-space dataset as a reference, selecting feature for estimating a transformation matrix for transforming k-space data, estimating a transformation matrix based on the feature of entire or part of the first partial k-space dataset and the feature of the second partial k-space dataset corresponding to the entire or part of the first partial k-space dataset, correcting the second partial k-space dataset based on the transformation matrix, and obtaining the corrected second partial k-space dataset. The present method is further used for partial Fourier reconstruction.Type: GrantFiled: April 9, 2019Date of Patent: October 24, 2023Assignees: University of Cincinnati, Children's Hospital Medical CenterInventors: Jinghua Wang, Lili He
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Patent number: 11796616Abstract: A method of performing multidimensional magnetic resonance imaging on a subject comprises collecting imaging data for a region of interest of the subject, the imaging data related to one or more spatially-varying parameters of the subject within the region of interest; collecting auxiliary data for the region of interest in the subject, the auxiliary data related to one or more time-varying parameters of the subject within the region of interest; linking the imaging data and the auxiliary data; and constructing an image tensor with one or more temporal dimensions based on at least a portion of the linked imaging data and at least a portion of the linked auxiliary data.Type: GrantFiled: May 28, 2021Date of Patent: October 24, 2023Assignee: CEDARS-SINAI MEDICAL CENTERInventors: Debiao Li, Anthony Christodoulou, Zhaoyang Fan, Zixin Deng, Nan Wang, Zhengwei Zhou, Sen Ma, Christopher Nguyen, Yibin Xie, Jaime Shaw
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Patent number: 11796619Abstract: Methods of assessing or obtaining an indication of the presence of a cognitive disorder by analysing microstructural changes in regions of the brain are provided. The invention particularly relates to methods of assessing or obtaining an indication of the presence of types of dementia, for example Alzheimer's disease, by analysing changes in minicolumns in regions or layers of the cortex of the brain or of the whole brain.Type: GrantFiled: December 8, 2020Date of Patent: October 24, 2023Assignee: Oxford University Innovation LimitedInventors: Steven Chance, Rebecca McKavanagh, Mark Jenkinson, Karla Miller
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Patent number: 11779258Abstract: A peripheral nerve conduction diagnosis system that utilizes an electrostimulation device having dry elastomer electrodes and a distance measuring device that allow a user to move the electrostimulation device along the skin of a patient while in constant contact with the skin and measure the distance moved.Type: GrantFiled: June 13, 2016Date of Patent: October 10, 2023Inventor: Tomasz Andrzej Kosierkiewicz
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Patent number: 11774383Abstract: The present invention relates to a method based on proton NMR technique to differentiate genuine and spurious Hand-rub formulations. This method identifies and estimates all four components present in WHO-recommended Hand-rub formulations. Further, this method also identifies the presence of non-recommended/additional components present in WHO-recommended Hand-rub formulations. The method described in this invention utilizes experimental parameters and derived equations to quantify all four components in just fifteen minutes without using any organic solvents.Type: GrantFiled: June 30, 2021Date of Patent: October 3, 2023Assignee: INDIAN OIL CORPORATION LIMITEDInventors: Ravindra Kumar, Sujit Mondal, Christopher Jayaraj, Gurpreet Singh Kapur, Sankara Sri Venkata Ramakumar
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Patent number: 11768257Abstract: Improved magnetic resonance imaging systems, methods and software are described including a low field strength main magnet, a gradient coil assembly, an RF coil system, and a control system configured for the acquisition and processing of magnetic resonance imaging data from a patient while utilizing a sparse sampling imaging technique.Type: GrantFiled: June 23, 2022Date of Patent: September 26, 2023Assignee: VIEWRAY TECHNOLOGIES, INC.Inventor: James F. Dempsey
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Patent number: 11747422Abstract: An approach to estimate noise, Rician signal bias and true signal in magnitude signal data obtained with magnetic resonance imaging. The method uses multiple measurements at different scan parameter settings, also referred to as weightings, and an iterative algorithm to estimate noise, expected signal and associated Rician signal bias. Measurements at all measured weighting levels contribute to the ultimate estimation of the bias-free signal decay function. Therefore, of the so processed magnetic resonance image data, weighted signals can be computed at arbitrary weighting levels and with considerably better signal-to-noise ratio than the originally obtained data at corresponding weightings. Bias-free weighted image data at desired weighting levels, maps of the decay function fit parameters, or maps of a combination of such decay function parameters can be used for rapid and highly sensitive tissue characterization.Type: GrantFiled: October 18, 2021Date of Patent: September 5, 2023Inventor: Stephan Maier
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Patent number: 11733334Abstract: A method of magnetic resonance (MR) imaging includes a phantom that is inexpensive to produce and enables simple, practical and fast assessment of image sharpness, in particular for checking image quality of MR imaging with spiral acquisition. The method includes subjecting a phantom, which comprises a volume filled with a bulk of granules of solid material surrounded by a liquid, to an imaging sequence, acquiring MR signals from the phantom, reconstructing an MR image from the acquired MR signals, and deriving a measure of the local image sharpness in two or more different image regions from the MR image, wherein each image region is a representation of a part of the phantom volume.Type: GrantFiled: June 17, 2019Date of Patent: August 22, 2023Assignee: Koninklijke Philips N.V.Inventors: Miha Fuderer, Silke Hey
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Patent number: 11733336Abstract: A method a for acquiring magnetic resonance data of an object under examination by means of a magnetic resonance system comprises: in an excitation phase, applying an RF excitation pulse; in a wait phase following the excitation phase, applying at least one first RF refocusing pulse after the applied RF excitation pulse according to a first echo spacing; in an acquisition phase following the wait phase, applying at least two further RF refocusing pulses to generate echo signals according to a second echo spacing, wherein the second echo spacing is smaller than the first echo spacing; and reading out the echo signals generated in the acquisition phase as magnetic resonance data from which image data can be reconstructed, wherein in the wait phase at least two spoiler gradients are switched in the readout direction.Type: GrantFiled: September 27, 2021Date of Patent: August 22, 2023Assignee: Siemens Healthcare GmbHInventors: Nadine Dispenza, Dominik Paul, Mario Zeller
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Patent number: 11733330Abstract: The disclosure relates to a magnetic resonance tomography scanner and to a method for operating the magnetic resonance tomography scanner. The method includes determining a B0 field map. The method further includes determining an excitation of the nuclear spins to be achieved and a spectrally selective excitation pulse for transmission by a transmitter by way of an antenna as a function of the B0 field map. In the method, the excitation pulse is configured here to generate the excitation of the nuclear spins to be achieved in the patient. The excitation pulse is then output by way of the antenna.Type: GrantFiled: February 5, 2021Date of Patent: August 22, 2023Assignee: Siemens Healthcare GmbHInventors: David Grodzki, Michael Köhler, Dieter Ritter
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Patent number: 11733338Abstract: An MRI phantom having an MRI compatible temperature measurement device having an MRI compatible body containing an MRI compatible fluid, wherein the device senses accurate temperature measurement within an MR Scanner environment using image processing of the contrast in signal between the areas of the image around the device and the fluid contained within the body of the device. The MRI Phantom may further include an internal expansion bladder device accomodating internal changes in pressure within the phantom, wherein the internal expansion bladder device includes frames supporting a pair of spaced membranes defining a chamber filled with a compressible gas.Type: GrantFiled: June 17, 2019Date of Patent: August 22, 2023Assignees: PSYCHOLOGY SOFTWARE TOOLS, INC, UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: Anthony P. Zuccolotto, John Dzikiy, Leroy K. Basler, Benjamin A. Rodack, Walter Schneider, Sudhir K. Pathak, Michael A. Boss
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Patent number: 11728038Abstract: Methods, computer-readable storage media and systems are described for constructing a three-dimensional electronic library of simulated decays of the diffusion-weighted 1H2O MR signal in b-space. Methods, computer-readable media, and systems are described for preparing a parametric tissue map for tissue in a subject. Computer readable media, having an electronic library of simulated decays of the diffusion-weighted 1H2O signal in b-space and method of using such a library.Type: GrantFiled: April 6, 2018Date of Patent: August 15, 2023Assignee: OREGON HEALTH & SCIENCE UNIVERSITYInventors: Charles Springer, Gregory Wilson, Jeffrey Maki, Thomas Barbara, Xin Li, William Rooney, Wei Huang, Brendan Moloney, Eric Baker
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Patent number: 11726157Abstract: A method for denoising magnetic resonance images and data is disclosed herein. An example method includes receiving a series of MRF images from a scanning device; identifying one or more subsets of voxels for the series of MRF images; generating one or more sets of eigenvectors, each set of the one or more sets of eigenvectors corresponding to one of the one or more subsets of voxels, and each eigenvector of the one or more sets of eigenvectors having a corresponding eigenvalue; applying a noise distribution model to each of the eigenvalues; identifying a subset of the eigenvalues as corresponding to noise based on the noise distribution model; and reconstructing the series of MRF images without the subset of eigenvalues identified as corresponding to noise.Type: GrantFiled: November 15, 2021Date of Patent: August 15, 2023Assignee: REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Matthew Zhu, Yun Jiang
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Patent number: 11719655Abstract: A method for measuring oil-water distribution using DNP-MRI, comprising adding a free radical for DNP enhanced NMR signal of a water phase or an oil phase in a sample containing oil and water; performing an MRI experiment on the sample, and collecting an MRI image of the sample without DNP enhancement; applying microwave excitation for DNP-MRI experiment under the same MRI experiment condition as step 2, and collecting an MRI image of the sample after DNP enhancement; and comparing the MRI image after DNP enhancement with the MRI image without DNP enhancement. In the MRI image with DNP enhancement, an area with enhanced MRI signal intensity is a selectively enhanced fluid phase distribution area, and an area without obviously changed MRI signal intensity is a non-selectively enhanced fluid phase distribution area. The method is simple, convenient to operate, short in measurement time, and high in measurement efficiency.Type: GrantFiled: November 5, 2021Date of Patent: August 8, 2023Assignee: Innovation Academy For Precision Measurement Science And Technology, Chinese Academy of SciencesInventors: Li Chen, Junfei Chen, Chaoyang Liu, Zhen Zhang, Tao Feng, Jiwen Feng, Fang Chen
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Patent number: 11698373Abstract: Apparatus and methods for the detection of proteins in biological fluids such as urine using a label-free assay is described. Specific proteins are detected by their binding to highly specific capture reagents such as SOMAmers that are attached to the surface of a substrate. Changes to these capture reagents and their local environment upon protein binding modify the behavior of color centers (e.g., fluorescence, ionization state, spin state, etc.) embedded in the substrate beneath the bound capture reagents. These changes can be read out, for example, optically or electrically, for an individual color center or as an average response of many color centers.Type: GrantFiled: February 15, 2022Date of Patent: July 11, 2023Assignee: SomaLogic Operating Co., Inc.Inventors: Jason Paul Cleveland, Karoly Holczer, Barry Patrick John Vant-Hull
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Patent number: 11694373Abstract: Methods for reconstructing images from undersampled k-space data using a machine learning approach to learn non-linear mapping functions from acquired k-space lines to generate unacquired target points across multiple coils are described.Type: GrantFiled: March 14, 2018Date of Patent: July 4, 2023Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Mehmet Akcakaya, Steen Moeller
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Patent number: 11624797Abstract: A system and method for correcting phase shift in echo images are provided. The method may include one or more of the following operations. A plurality of echo images may be obtained. Homogeneous pixels in the plurality of echo images may be identified. A vector corresponding to each of at least some of the identified homogeneous pixels may be determined. A vector of a homogenous pixel includes a phase element and an amplitude element. A first complex linear model of phase shift may be determined based at least in part on the determined vectors. Phase shift of at least one of the plurality of echo images may be corrected based on the first complex linear model.Type: GrantFiled: February 21, 2021Date of Patent: April 11, 2023Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yanen Guo, Zhongqi Zhang
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Patent number: 11609289Abstract: In a method for providing setting parameter sets for at least one measuring protocol described by protocol parameters for acquiring magnetic resonance data with a magnetic resonance facility, setting parameter set is determined for each of at least two temperature status categories of the magnetic resonance facility using a temperature model describing a development of a temperature status of at least one component of the magnetic resonance facility. The method also includes preventing overheating of the at least one component due to the measurement with the measuring protocol being repeated a maximum number of times for a specified number of repetitions.Type: GrantFiled: September 24, 2020Date of Patent: March 21, 2023Assignee: Siemens Healthcare GmbHInventors: Thorsten Feiweier, Michael Köhler
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Patent number: 11586966Abstract: Techniques regarding the development and/or analysis of one or more quantum computing programs are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a circuit component, operatively coupled to the processor, that can create a quantum computing program over a period of time. The computer executable components can also comprise a visualization component, operatively coupled to the processor, that can generates a quantum state visualization that depicts a characterization of the quantum computing program over the period of time.Type: GrantFiled: December 5, 2018Date of Patent: February 21, 2023Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Sanjana Arun Sharma, Anna Obikane, Francisco José Cabrera Hernández, Jay M. Gambetta