To Obtain Localized Resonance Within A Sample Patents (Class 324/309)
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Patent number: 12235339Abstract: In a method for determining a fat-reduced MR image, a first MR image is provided having, apart from the other tissue constituents, MR signals from only one of the two fat constituents, the first MR image is applied to a trained ANN, which was trained by first MR training data as the input data, the training data including, apart from the other tissue constituents, MR signals from only the one of the two fat constituents, and using second MR training data as a base knowledge, the second MR training data including, apart from the other tissue constituents, no MR signals from the two fat constituents; and an MR output image is determined from the trained ANN, to which the first MR image was applied, as a fat-reduced MR image, wherein the fat-reduced MR image includes, apart from the other tissue constituents, no MR signals from the two fat constituents.Type: GrantFiled: August 2, 2022Date of Patent: February 25, 2025Assignee: Siemens Healthineers AGInventor: Mario Zeller
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Patent number: 12235166Abstract: Provided is a probe system for low-temperature high-precision heat transport measurement, the probe system including a sample loader where a sample is loaded. In the probe system for low-temperature high-precision heat transport measurement, the sample loader includes a first frame including a sample loading space, and a second frame including an open end coupled to the first frame to accommodate the sample loading space.Type: GrantFiled: October 17, 2019Date of Patent: February 25, 2025Assignees: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, INSTITUTE FOR BASIC SCIENCEInventors: Je Geun Park, Ha Leem Kim, Matthew John Coak
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Patent number: 12228627Abstract: A computer-implemented method for determining a subset of coil elements for capturing a magnetic resonance tomography recording, comprises: providing a target volume in a scout view, and determining a plurality of subsets of coil elements from among the plurality of coil elements, wherein individual subsets are configured different from one another. The method further comprises: determining at least one quality criterion for each subset of coil elements, wherein the at least one quality criterion of a corresponding subset of coil elements relates to an image quality in the target volume, dependent upon the corresponding subset of coil elements; determining the subset of coil elements from the plurality of subsets, based on the corresponding at least one quality criterion; and providing an information item regarding which of the plurality of coil elements are included by the subset of coil elements.Type: GrantFiled: September 12, 2022Date of Patent: February 18, 2025Assignee: SIEMENS HEALTHINEERS AGInventors: Hans-Peter Fautz, Stephan Kannengiesser, Jeanette Lenger
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Patent number: 12229917Abstract: Methods and systems are provided for training machine learning models to filter medical images with a reduced incidence of filtering artifact inclusion. In one example, training data may be generated by applying a filter to a medical image to produce a filtered medical image, wherein a subregion of the filtered medical image includes a filtering artifact, displaying the filtered medical image via a display device, receiving a selection of the subregion of the filtered medical image from a user input device, blending, in the subregion, pixel intensity values from the filtered medical image with pixel intensity values from the medical image, to produce a blended image, wherein a visibility of the filtering artifact is attenuated in the blended image, and displaying the blended image via the display device.Type: GrantFiled: May 20, 2022Date of Patent: February 18, 2025Assignee: GE PRECISION HEALTHCARE LLCInventor: Erik Normann Steen
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Patent number: 12228628Abstract: In a method to improved positioning of slices in which measurement data is to be recorded, a planning image of an examination object is provided that has been distortion-corrected using non-linearity data describing a non-linearity of a gradient unit of the magnetic resonance system, a desired field of view and desired slices in the at least one planning image are selected, a measurement protocol to record the measurement data is loaded, switchable gradients and/or emittable RF pulses are adapted, as a function of the non-linearity data that has been loaded and the desired slices, such that the desired slices are excited despite the non-linearities of the gradient unit, and the loaded measurement protocol is performed in the selected field of view, using the adapted gradients to be switched and/or adapted RF pulses. The measurement protocol may include switchable gradients and the emittable RF pulses.Type: GrantFiled: December 30, 2022Date of Patent: February 18, 2025Assignee: Siemens Healthineers AGInventor: David Grodzki
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Patent number: 12222413Abstract: In a method for magnetic resonance imaging pseudorandomly undersampled k-space imaging data is acquired with multiple receiver coils of an MRI imaging apparatus. MR image reconstruction is performed to produce a reconstructed MR image from the k-space imaging data by iteratively solving sketched approximations of an original reconstruction problem. The sketched approximations use a sketched model matrix As that is a lower-dimensional version of an original model matrix A of the original reconstruction problem. The sketched model matrix As preserves the Fourier structure of the MR reconstruction problem and reduces the number of coils actively used during reconstruction.Type: GrantFiled: May 13, 2022Date of Patent: February 11, 2025Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Julio A. Oscanoa Aida, Frank Ong, Mert Pilanci, Shreyas S. Vasanawala
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Reference device for real-time tracking of bone and/or surgical objects in computer-assisted surgery
Patent number: 12220177Abstract: Reference device (1) for real-time tracking of bone and/or surgical objects in computer-assisted surgery, the device (1) comprising: A) an upper member (2) having at least one circular cylindrical hole (3) penetrating through the upper member (2) from the upper surface (5) to the lower surface (6), wherein the hole (3) defines a circular cylindrical reference element (15) having a diameter d and a height h, the ratio between the diameter d and the height h of the reference element (15) is minimum ?, and B) a lower member (4) configured to cover the lower orifices (8) of the holes (3); and wherein C) the upper member (2) is configured as a plate shaped body.Type: GrantFiled: February 5, 2019Date of Patent: February 11, 2025Assignee: AO Technology AGInventors: Jan Buschbaum, Markus Windolf -
Patent number: 12224725Abstract: A lookup table calibration apparatus and method are disclosed. The lookup table calibration apparatus includes a power amplifier circuit configured to amplify a radio frequency (RF) signal having time-variant power levels based on a modulated voltage. To ensure proper alignment between the modulated voltage and the time-variant power levels, the power amplifier circuit is further configured to phase-shift the RF signal based on a modulated phase correction voltage. Specifically, the modulated voltage is generated based on a modulated voltage lookup table and the modulated phase correction voltage is generated based on a phase correction voltage lookup table. Herein, the lookup table calibration apparatus can be configured to concurrently populate and/or calibrate the modulated voltage lookup table and the phase correction voltage lookup table based on a measured gain and a measured phase of the RF signal, respectively.Type: GrantFiled: December 16, 2021Date of Patent: February 11, 2025Assignee: Qorvo US, Inc.Inventor: Nadim Khlat
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Patent number: 12216186Abstract: Scan time in diffusion-relaxation magnetic resonance imaging (“MRI”) is reduced by implementing time-division multiplexing (“TDM”). In general, time-shifted radio frequency (“RF”) pulses are used to excite two or more imaging volumes. These RF pulses are applied to induce separate echoes for each slice. Diffusion MRI data can thus be acquired with different echo times, or alternatively with the same echo time, in significantly reduced overall scan time. Multidimensional correlations between diffusion and relaxation parameters can be estimated from the resulting data.Type: GrantFiled: June 3, 2021Date of Patent: February 4, 2025Assignees: The Brigham and Women's Hospital, Inc., Children's Medical Center CorporationInventors: Lipeng Ning, Yogesh Rathi, Yang Ji, Borjan Gagoski
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Patent number: 12210081Abstract: In a motion correction method, a reference navigation image is obtained before MR data collection is performed on a target region of interest; in a process of performing the MR data collection on the target region of interest, motion detection is performed using a pilot tone signal received by a plurality of coils, and when a motion is detected, MR data collected when the motion occurs is marked as motion damage data; a post-motion navigation image is obtained when the end of the motion is detected by utilizing the pilot tone signal; registration is performed on the post-motion navigation image and the reference navigation image to obtain a motion correction parameter corresponding to the motion; and motion correction on the MR data collection is performed using the motion correction parameter. The method according to the present disclosure advantageously improves MR imaging quality.Type: GrantFiled: September 28, 2022Date of Patent: January 28, 2025Assignee: Siemens Healthineers AGInventors: Fang Dong, Yan Tu Huang
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Patent number: 12207960Abstract: A radiation suite includes a room having a floor, a ceiling, and one or more walls, a radiation system including a gantry enclosing a radiation source and a couch, and an image projection system operable to project an image on a projection surface on at least a portion of the gantry and/or the couch, providing a calming environment for a patient to relax. The image projection system comprises a computer and one or more projectors operably controlled by the computer. The computer comprises a mapping software operable to map an image file to the projection surface. The one or more projectors are operable to project the mapped image file on the projection surface.Type: GrantFiled: May 12, 2023Date of Patent: January 28, 2025Assignee: VARIAN MEDICAL SYSTEMS, INC.Inventors: Rachel Rieger, Nitin Mangi, Roberto Luevano, Ross Hannibal
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Patent number: 12205018Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium. In one aspect, a method includes the actions of receiving a request to perform computations for a neural network on a hardware circuit having a matrix computation unit, the request specifying a transpose operation to be performed on a first neural network matrix; and generating instructions that when executed by the hardware circuit cause the hardware circuit to transpose the first neural network matrix by performing first operations, wherein the first operations include repeatedly performing the following second operations: for a current subdivision of the first neural network matrix that divides the first neural network matrix into one or more current submatrices, updating the first neural network matrix by swapping an upper right quadrant and a lower left quadrant of each current submatrix, and subdividing each current submatrix into respective new submatrices to update the current subdivision.Type: GrantFiled: June 5, 2023Date of Patent: January 21, 2025Assignee: Google LLCInventors: Reginald Clifford Young, Geoffrey Irving
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Patent number: 12205279Abstract: For reconstruction in medical imaging using phase correction, a machine learning model is trained for reconstruction of an image. The reconstruction may be for a sequence without repetitions or may be for a sequence with repetitions. Where repetitions are used, rather than using just a loss for that repetition in training, the loss based on an aggregation of images reconstructed from multiple repetitions may used to train the machine learning model. In either approach, a phase correction is applied in machine training. A phase map is extracted from output of the model in training or extracted from the ground truth of the training data. The phase correction, based on the phase map, is applied to the ground truth and/or the output of the model in training. The resulting machine-learned model may better reconstruct an image as a result of having been trained using phase correction.Type: GrantFiled: March 17, 2022Date of Patent: January 21, 2025Assignee: Siemens Healthineers AGInventors: Simon Arberet, Marcel Dominik Nickel, Thomas Benkert, Mariappan S. Nadar
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Patent number: 12204008Abstract: According to a method, first MR reference data and first MR imaging data are captured. Further MR imaging data is then captured. The capturing includes in each case generating at least one excitation pulse with a transmit coil of the magnetic resonance apparatus and irradiating the at least one excitation pulse into a patient receiving region, generating MR signals in a generation region using the at least one excitation pulse, and receiving the MR signals as MR data with a receive coil. A degree of difference that describes a difference between the generation region on capture of the first MR reference data and the generation region on capture of the further MR imaging data is determined. MR reference data is provided as a function of the degree of difference. An MR image is reconstructed based on the captured further MR imaging data and the provided further MR reference data.Type: GrantFiled: December 7, 2021Date of Patent: January 21, 2025Assignee: Siemens Healthineers AGInventors: Mario Zeller, Dominik Paul
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Patent number: 12204007Abstract: Disclosed herein is a medical system (100, 300, 500) comprising a memory (110) storing machine executable instructions (120) and a B0 field estimation module (126); and a computational system (106). Execution of the machine executable instructions causes the computational system to receive (200) an initial magnetic resonance image (122) that comprises a magnitude component and is descriptive of a first region (326) of interest of a subject (118).Type: GrantFiled: June 10, 2021Date of Patent: January 21, 2025Assignee: Koninklijke Philips N.V.Inventors: Umesh Suryanarayana Rudrapatna, Jaladhar Neelavalli, Karthik Gopalakrishnan, Suthambhara Nagaraj, Naveen Bajaj, Rupesh Vakkachi Kandi
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Patent number: 12196831Abstract: Methods and systems perform magnetic resonance fingerprinting (MRF) by obtaining magnetic resonance data over a main field-of-view (FOV) and resulting from providing a magnetic resonance fingerprinting pulse sequence to a sample. The pulse sequence includes gradient waveforms and radio frequency (RF) pulses that have pulse sequence parameters specifically tailored for scanning, not the entire main FOV but rather a reduced portion of that main FOV. The methods and systems further include comparing the magnetic resonance data from the sample to a fingerprint dictionary of signal profiles that specifically correspond to the reduced portion of the main FOV and generating tissue property maps that correspond only to that reduced portion.Type: GrantFiled: November 18, 2022Date of Patent: January 14, 2025Assignee: REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Vikas Gulani, Nicole Seiberlich, Jon-Fredrik Nielsen, Yun Jiang
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Patent number: 12196827Abstract: The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.Type: GrantFiled: June 2, 2021Date of Patent: January 14, 2025Assignee: Universiteit TwenteInventors: Melissa Mathilde van de Loosdrecht, Hendrikus Johannes Gradus Krooshoop, Bernard ten Haken, Lejla Alic
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Patent number: 12198232Abstract: A method is for acquiring a magnetic resonance (MR) image dataset of at least two slices via simultaneous multi-slice excitation. An embodiment of the method includes executing an MR imaging sequence using multi-band radio-frequency excitation pulses to excite the at least two slices simultaneously in at least two repetitions, the repetitions each being executed according to a phase modulation scheme in which each of the simultaneously excited slices is assigned a phase and the phase of at least one of the simultaneously excited slices is changed from one repetition to the next, thereby acquiring an MR dataset of a collapsed image in each repetition; performing a spatial registration between the at least two collapsed images and performing motion correction on at least one of the MR datasets of the collapsed images; and reconstructing MR images of the at least two slices from the corrected MR datasets of the collapsed images.Type: GrantFiled: October 14, 2021Date of Patent: January 14, 2025Assignee: SIEMENS HEALTHINEERS AGInventors: Mario Zeller, Dominik Paul, Wei Liu
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Patent number: 12193803Abstract: The present disclosure is related to systems and methods for magnetic resonance imaging (MRI). The method includes obtaining a plurality of target sets of k-space data by filling target MR signals acquired by a plurality of coils of an MRI device into k-space along a corkscrew trajectory. The method includes obtaining a coil sensitivity of each of the plurality of coils. The method includes obtaining a point spread function corresponding to the corkscrew trajectory. The method includes generating a target image based on an objective function.Type: GrantFiled: June 24, 2021Date of Patent: January 14, 2025Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Jingyuan Lyu, Yongquan Ye
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Patent number: 12196824Abstract: A medical system is provided with: a medical device that is inserted inside a living body; a distal end electrode that is disposed at a distal end of the medical device, and passes a high frequency to the living body from inside the living body; a magnetic sensor that is disposed outside the living body, and detects a magnetic field generated by the high frequency that has been passed from the distal end electrode to the living body; and an image generation portion that generates an internal image of the living body using magnetic field information output from the magnetic sensor.Type: GrantFiled: December 9, 2022Date of Patent: January 14, 2025Assignee: ASAHI INTECC CO., LTD.Inventor: Fumiyoshi Oshima
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Patent number: 12196832Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.Type: GrantFiled: July 1, 2021Date of Patent: January 14, 2025Assignee: Koninklijke Philips N.V.Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Peter Koken, Kay Nehrke
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Patent number: 12196833Abstract: Systems and methods for generative adversarial networks (GANs) to remove artifacts from undersampled magnetic resonance (MR) images are described. The process of training the GAN can include providing undersampled 3D MR images to the generator model, providing the generated example and a real example to the discriminator model, applying adversarial loss, L2 loss, and structural similarity index measure loss to the generator model based on a classification output by the discriminator model, and repeating until the generator model has been trained to remove the artifacts from the undersampled 3D MR images. At runtime, the trained generator model of the GAN can be generate artifact-free images or parameter maps from undersampled MRI data of a patient.Type: GrantFiled: May 19, 2021Date of Patent: January 14, 2025Assignees: Siemens Healthineers AG, The Regents of the University of CaliforniaInventors: Peng Hu, Xiaodong Zhong, Chang Gao, Valid Ghodrati
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Patent number: 12196829Abstract: A resonance circuit includes: an inductor formed along a surface of a first cylindrical form having a central axis; and a capacitor formed along a surface of a second cylindrical form having the central axis, wherein the inductor and the capacitor are electrically connected to each other to form a closed loop.Type: GrantFiled: December 22, 2022Date of Patent: January 14, 2025Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Konami Izumi, Yutaka Fujii, Yu Suzuki
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Patent number: 12196828Abstract: Methods and systems perform magnetic resonance fingerprinting (MRF) that provides tissue characterization through simultaneous quantification of water tissue properties and proton density fat fraction (PDFF), by using water-only and fat-only images from MRF. MRF is performed using rosette trajectories scanning k-space to effectively isolate water tissue and fat tissue, by separating these rosette trajectories into individual segments that are then analyzed to enable signals from fat tissue to be distinguished from water.Type: GrantFiled: November 18, 2022Date of Patent: January 14, 2025Assignee: REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Nicole Seiberlich, Yun Jiang, Jesse Hamilton, Yuchi Liu
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Patent number: 12188900Abstract: Embodiments of the present invention relate to a system and method for performing temperature-dependent measurements of a magnetic nanoparticle sample. The system includes high frequency coils and sample temperature tunable assembly to determine the specific relaxation process for magnetic nanoparticle sample using both time and frequency domain techniques. During the temperature-dependent measurements of a magnetic nanoparticle sample, system in accordance with embodiments of the present invention resolve the nanoparticle dynamics using a temperature-tunable dual mode, AC susceptibility and magnetic relaxometry, to cover a broad range of frequencies and time scales. Other operational modes of the invention can drive the nanoparticles with arbitrary waveforms (sinusoidal, sum of sinusoids, or repeated pulses) to elicit and measure tailored response behavior from the magnetic nanoparticle sample.Type: GrantFiled: February 11, 2022Date of Patent: January 7, 2025Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCEInventors: Thinh Quoc Bui, Solomon Isaac Woods, Weston Leo Tew, Jr.
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Patent number: 12186067Abstract: A method may include obtaining a plurality of imaging signals collected by applying a wave encoding gradient to a region of interest (ROI) of a subject. The method may also include obtaining a plurality of auxiliary signals associated with the ROI. The method may also include obtaining a point spread function corresponding to the wave encoding gradient. The method may also include determining, based on the plurality of auxiliary signals, temporal information relating to at least one temporal dimension of the ROI. The method may also include determining, based on the plurality of auxiliary signals, the plurality of imaging signals, and the point spread function, spatial information relating to at least one spatial dimension of the ROI. The method may also include generating at least one target image of the ROI based on the temporal information and the spatial information.Type: GrantFiled: December 23, 2021Date of Patent: January 7, 2025Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Jingyuan Lyu, Qi Liu, Yongquan Ye, Jian Xu, Zhongqi Zhang
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Patent number: 12186105Abstract: A subject information acquisition apparatus, comprises: a signal generation unit configured to generate a high-frequency signal corresponding to each of the frequencies; an acquisition unit configured to acquire a plurality of detection signals based on at least one of a reflection signal and a transmission signal; a signal selection unit configured to select at least one detection signal from the plurality of detection signals based on an index value of the plurality of detection signals; a coupling amount detecting unit configured to detect a coupling amount of near-field coupling due to an electric field between the antenna and the subject based on a detection signal; and a displacement detecting unit configured to generate a displacement signal indicating a displacement of the subject based on the coupling amount.Type: GrantFiled: December 7, 2021Date of Patent: January 7, 2025Assignees: CANON KABUSHIKI KAISHA, CANON MEDICAL SYSTEMS CORPORATIONInventors: Ryuichi Nanaumi, Kazuya Okamoto, Takafumi Ohishi
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Patent number: 12186104Abstract: The devices, systems, and methods can improve magnetic resonance imaging (MRI), MR spectroscopy (MRS), MR spectroscopic imaging (MRSI) measurement(s), thereby providing more reliable quantification. The method may include a method for correcting MR image(s)/spectrum. The method may include providing an inhomogeneity field/response map of a region of interest; and providing MR image(s)/spectrum of the region of interest. The method may include determining an intravoxel/voxel inhomogeneity correction coefficient for each voxel of at least one subregion of the region of the interest using the inhomogeneity field/response map. The method may include correcting each voxel of the MR image(s)/spectrum of the region of interest using the intravoxel/voxel inhomogeneity correction coefficient.Type: GrantFiled: June 30, 2020Date of Patent: January 7, 2025Assignee: Emory UniversityInventor: Phillip Zhe Sun
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Patent number: 12189009Abstract: In a method for determining at least one test position for a test measurement to be recorded by means of a magnetic resonance system, a test image is recorded, and at least one test position is selected based on the test image. With methods for the compensation of effects of deviations of gradients actually generated during a readout duration from gradients planned for this readout time duration, the selection of test positions according to the disclosure based on a test image advantageously ensures that the test positions lie in a recording region favorable for the test measurement, e.g. also within an examination object to be examined in the test image. A higher image quality in MR images, which were generated using test measurements carried out at test positions positioned according to the disclosure, can therefore be achieved.Type: GrantFiled: September 29, 2022Date of Patent: January 7, 2025Assignee: Siemens Healthineers AGInventors: Mario Zeller, Adam Kettinger
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Patent number: 12189004Abstract: Accurate measurement of gradient waveform errors can often improve image quality in sequences with time varying readout and excitation waveforms. Self-encoding or offset-slice method sequences are commonly used to measure gradient waveforms. However, the self-encoding method requires a long scan time, while the offset-slice method is often low precision, requiring the thickness of the excited slice to be small compared to the maximal k-space encoded by the test waveform. This disclosure describes a novel hybrid of those methods, referred to as variable-prephasing (VP). Like the offset-slice method, VP uses the change in signal phase from offset-slices to calculate the gradient waveform. Similar to the self-encoding method, repeated acquisitions with a variable amplitude self-encoding gradient mitigates the signal loss due to phase wrapping, which, in-turn, allows thicker slices and greater SNR.Type: GrantFiled: February 3, 2023Date of Patent: January 7, 2025Assignee: Vanderbilt UniversityInventors: Kevin Harkins, Mark D. Does
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Patent number: 12181551Abstract: The present invention discloses a magnetic resonance fingerprinting imaging method with variable number of echoes, in addition to conventional MRF coding such as changing the excitation pulse angle, the method also introduces the change of the number of echoes, so that quantitative maps of B0, B1+, T1 and T2* can be obtained in a single scan. Further, if the echo time corresponding to the in-phase, opposed-phase and in-phase of water and fat is set for three consecutive echoes, the present invention can also image water and fat, and achieve the accurate quantification of B0, B1+, T1w, T1F, [T2*]w and [T2*]F. Through in vivo experiments and simulations, the effectiveness of the present invention has been proved. Therefore, the present invention can provide multiple information representations for common brain diseases (glioma) and fatty diseases (such as lipoma, fatty liver, etc.), which is conducive to clinical diagnosis and treatment.Type: GrantFiled: November 18, 2022Date of Patent: December 31, 2024Assignee: ZHEJIANG UNIVERSITYInventors: Huihui Ye, Jinmin Xu, Huafeng Liu
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Patent number: 12181549Abstract: A method for determining a B0 map for, for example, performing an imaging magnetic resonance measurement using a magnetic resonance apparatus, includes measuring an original magnetic field distribution in a measurement volume of the magnetic resonance apparatus, and computing a final B0 map that describes a magnetic field distribution produced in the measurement volume of the magnetic resonance apparatus by setting a shim state. The magnetic field distribution produced in the measurement volume of the magnetic resonance apparatus by setting the shim state differs from the original magnetic field distribution.Type: GrantFiled: December 1, 2022Date of Patent: December 31, 2024Assignee: Siemens Healthineers AGInventors: David Grodzki, Dieter Ritter, Armin Nagel, Christian Eisen
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Patent number: 12179033Abstract: A method to guide a targeted neurostimulation to the brain of a patient. Neuroimaging data is sensed from the brain of the patient. A processor is used to evaluate the neuroimaging data in order to calculate result data for a modeled functional measure of a particular brain network which defines a first brain region and a second brain region. A target location is determined in the first brain region based upon the result data and a functional connection measure between first and second brain region. A transcranial magnetic stimulator is adjusted to provide a magnetic stimulation signal for stimulation of the target location.Type: GrantFiled: September 12, 2023Date of Patent: December 31, 2024Inventor: Michael Sasha John
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Patent number: 12178562Abstract: A method for performing a magnetic resonance measurement of a patient using a magnetic resonance apparatus is provided. The magnetic resonance apparatus includes a radiofrequency antenna unit for producing an excitation pulse. A first B0 field map for a first motion state of the patient, and a second B0 field map for a second motion state of the patient are provided. A first excitation pulse for the first motion state, and a second excitation pulse for the second motion state are determined based on the first B0 field map and the second B0 field map. A magnetic resonance measurement is performed, during which the motion state of the patient is monitored. When the patient is in the first motion state, the radiofrequency antenna unit transmits the first excitation pulse. When the patient is in the second motion state, the radiofrequency antenna unit transmits the second excitation pulse.Type: GrantFiled: March 17, 2022Date of Patent: December 31, 2024Assignee: Siemens Healthineers AGInventors: David Grodzki, Dieter Ritter
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Patent number: 12171541Abstract: A magnetic resonance imaging apparatus includes sequence controlling circuitry configured: to obtain, during a time period after excitation of a first nuclide in a hyperpolarized state but no later than before obtainment of a first magnetic resonance signal from the first nuclide, a second magnetic resonance signal from a second nuclide that is different from the first nuclide and is in a non-hyperpolarized state, by exciting the second nuclide; and to control each of gradient magnetic field waveforms so as to cause both a first sum indicating a sum of application amounts of a gradient magnetic field related to the excitation of the second nuclide and a second sum indicating a sum of application amounts of a gradient magnetic field related to the obtainment of the second magnetic resonance signal to be close to zero, no later than before the obtainment of the first magnetic resonance signal.Type: GrantFiled: February 8, 2023Date of Patent: December 24, 2024Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Ryohei Takayanagi, Takaya Mori, Kagami Fujita, Akihiro Taguchi, Masao Yui
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Patent number: 12164012Abstract: A magnetic resonance (MR) system compensation interface having: a hardware subinterface configured to receive individual hardware parameters from an individual scan unit of an MR system; a model determination unit configured to determine an imperfection model on the basis of the hardware parameters; a compensation model determination unit configured to determine a compensation model on the basis of the imperfection model; an application subinterface configured to receive application data assigned to an application; and a compensation unit configured to determine compensated application data on the basis of the received application data and the determined compensation model.Type: GrantFiled: December 8, 2022Date of Patent: December 10, 2024Assignee: Siemens Healthineers AGInventors: Uvo Hölscher, Christoph Forman, Peter Gall
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Patent number: 12164014Abstract: A method for measuring concomitant fields in a magnetic resonance (MR) system is provided. The method includes applying a measurement pulse sequence in a plurality of acquisitions. Applying the measurement pulse sequence further includes applying a first bipolar gradient pulse in a first acquisition, applying a second bipolar gradient pulse in reverse polarities from the first bipolar gradient pulse in a second acquisition, and applying the measurement pulse sequence without a bipolar gradient pulse in a third acquisition. The method further includes acquiring MR signals emitted from the subject, and generating phase images based on the MR signals. The method also includes generating volumetric vector field maps based on the phase images, wherein the volumetric vector field maps include concomitant field at each spatial location in a 3D volume, the concomitant field represented as a vector. In addition, the method includes outputting the volumetric vector field maps.Type: GrantFiled: January 18, 2023Date of Patent: December 10, 2024Assignee: GE PRECISION HEALTHCARE LLCInventors: Seung-Kyun Lee, Afis Ajala
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Patent number: 12158512Abstract: A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity.Type: GrantFiled: January 19, 2023Date of Patent: December 3, 2024Assignee: TURING MEDICAL TECHNOLOGIES INC.Inventors: Chad Sylvester, Deanna Greene, Scott Marek, Scott Norris, Jarod Roland, Evan Gordon, Timothy Laumann, Damien Fair, Kenneth Bruener, Nico Dosenbach
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Patent number: 12151125Abstract: Ultrasound transducers adjust the B1+ and/or B1? field distribution in an MRI apparatus to improve the signal sensitivity and homogeneity at a region of interest. Approaches employed include strategic placement of field-altering features such as slots and/or dipoles along the exterior surface or, in some cases, the interior of the transducer. In various embodiments, the field-altering features are (or behave as) passive resonators.Type: GrantFiled: June 5, 2020Date of Patent: November 26, 2024Assignee: INSIGHTEC LTD.Inventor: Boaz Shapira
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Patent number: 12153114Abstract: A method for 3D oscillating-gradient prepared gradient spin-echo imaging and a device. The imaging method comprises the following steps: first, using a global saturation module to destroy previous residual transverse magnetization; second, embedding a pair of trapezoidal cosine oscillating gradients into a 90°x-180°y-90°?x radiofrequency pulse by a diffusion encoding module, to separate diffusion encoding from signal acquisition; then, using a fat saturation module to suppress a fat signal; finally, acquiring a signal by means of gradient spin-echo readout, and correcting phase errors among multiple excitations by multiplexed sensitivity-encoding reconstruction. Compared with a 2D plane echo-based oscillating gradient diffusion sequence used on a 3T clinical system, a 3D oscillating-gradient prepared gradient spin-echo sequence effectively reduces the imaging time, improves the signal to noise ratio, and is beneficial to clinical transformation of time-dependent diffusion MRI technology.Type: GrantFiled: September 26, 2022Date of Patent: November 26, 2024Assignee: ZHEJIANG UNIVERSITYInventors: Dan Wu, Haotian Li, Yi Zhang
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Patent number: 12153111Abstract: A method for magnetic resonance imaging performs chemical shift encoded imaging to produce complex dual-echo images which are then applied (with imaging parameters) as input to a deep neural network to produce as output water-only and fat-only images. The deep neural network can be trained with ground truth water/fat images derived from chemical shift encoded images using a conventional water-fat separation algorithm such as projected power approach, IDEAL, or VARPRO. The chemical shift encoded imaging comprises performing an image acquisition with the MRI scanner via a spoiled-gradient echo sequence or a spin-echo sequence.Type: GrantFiled: January 27, 2023Date of Patent: November 26, 2024Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Shreyas S. Vasanawala, Yan Wu
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Patent number: 12150747Abstract: Even when imaging is aborted, data collected so far is utilized in image reconstruction, thereby enhancing examination efficiency. A certain priority imaging data available for image reconstruction by a fast-imaging method is determined, when collecting k-space data according to a predetermined imaging method. If collection of the certain priority imaging data is completed when imaging is aborted, imaging reconstruction is executed using the priority imaging data. The priority imaging data is determined based on a relationship between the imaging method under execution, and the fast-imaging method underlying determination of the priority imaging data.Type: GrantFiled: June 1, 2021Date of Patent: November 26, 2024Assignee: FUJIFILM CORPORATIONInventor: Yusuke Hoshino
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Patent number: 12146932Abstract: A magnetic resonance imaging (MRI) system and method integrating multi-nuclide synchronous imaging and spectral imaging is provided. The MRI system includes a spectral imaging module, a multi-nuclide synchronous imaging module, and a spectral reconstruction and image fusion module, where the spectral imaging module is configured to acquire a spectrum of a nuclide Nuc; the multi-nuclide synchronous imaging module is configured to perform synchronous imaging of nuclides Nuc1 . . . Nucn, where when n=1, Nucl is 1H; and when n>1, Nucn is a non-1H nuclide; and the spectral reconstruction and image fusion module is configured to receive the spectrum of the nuclide Nuc and images of the nuclides Nuc1 . . . Nucn, and acquire spatial distribution information of compounds of the nuclide Nuc and spatial distribution information of the non-1H nuclide through fusion. The system and method can synchronously acquire MR signals of different nuclides, and reconstruct and fuse non-1H nuclide images.Type: GrantFiled: February 21, 2024Date of Patent: November 19, 2024Assignee: HARBIN MEDICAL UNIVERSITYInventors: Xilin Sun, Chunsheng Yang, Kai Wang, Yongyi Wu, Lijiao Wang, Lili Yang, Lina Wu
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Patent number: 12148160Abstract: This invention discloses a method for quantitatively measuring the water exchange rate across myelin sheath. The method involves the following steps: acquiring images using the FEXI sequence; identifying anisotropic regions and the orientation of neural fibers at each pixel within these regions; selecting images where the diffusion weighted directions are perpendicular to the orientation of neural fibers at each pixel within the anisotropic regions and numerically averaging the selected images; calculating the apparent exchange rate (AXR), the apparent diffusion coefficient (ADC), and the filter coefficient (?) using the numerically averaged images, where AXR serves as a specific parameter reflecting the water exchange rate across myelin sheath. The method provided by this invention enables specific detection of the exchange process of water molecules inside and outside the myelin sheath and analysis of the apparent water exchange rate across myelin sheath.Type: GrantFiled: December 6, 2022Date of Patent: November 19, 2024Assignee: ZHEJIANG UNIVERSITYInventors: Ruiliang Bai, Zhaoqing Li
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Patent number: 12138081Abstract: An asthma management system and method are disclosed for collecting environmental and individual health data to predict the onset of asthma symptoms to allow for preventative therapy tailored on an individual basis. In one embodiment a computer system is in electrical communication with an individual user interface and one or more environmental factor collection points via a communications network. The user interface is adapted to send and receive asthma-related data including asthma profile and real-time asthma status data to the computer system via the communication network, and the environmental factor collection points are adapted to send and receive data to the computer system via the communications network.Type: GrantFiled: June 16, 2020Date of Patent: November 12, 2024Assignee: CAIRE Diagnostics Inc.Inventors: Solomon Ssenyange, Ryan Leard, David Anvar, Brian Awabdy, Todd Smith, Vivek Balasubramanyam
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Patent number: 12143413Abstract: A system and method is described that sends multiple simulated phishing emails, text messages, and/or phone calls (e.g., via VoIP) varying the quantity, frequency, type, sophistication, and combination using machine learning algorithms or other forms of artificial intelligence. In some implementations, some or all messages (email, text messages, VoIP calls) in a campaign after the first simulated phishing email, text message, or call may be used to direct the user to open the first simulated phishing email or text message, or to open the latest simulated phishing email or text message. In some implementations, simulated phishing emails, text messages, or phone calls of a campaign may be intended to lure the user to perform a different requested action, such as selecting a hyperlink in an email or text message, or returning a voice call.Type: GrantFiled: August 28, 2022Date of Patent: November 12, 2024Assignee: KnowBe4, Inc.Inventors: Alin Irimie, Stu Sjouwerman, Greg Kras, Eric Sites
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Patent number: 12140655Abstract: A dynamic magnetic resonance angiography, MRA, method, comprising: acquiring, by an MR scanning device, a multi-contrast magnetic resonance, MR, sequence of a portion of a body; identifying, by a processing circuit, blood vessels of the portion by identifying blood of the portion based on predetermined characteristic of blood and the multi-contrast MR sequence; generating, by the processing circuit, a first MRA image frame and a second MRA image frame, based on the multi-contrast MR sequence, respectively visualising a first part and a second part of the identified blood vessels; generating, by the processing circuit, a dynamic MRA image for visualising a dynamic blood flow through a part of the portion, based on the first and second MRA image frame.Type: GrantFiled: April 15, 2020Date of Patent: November 12, 2024Assignee: SYNTHETICMR AB (PUBL)Inventor: Marcel Warntjes
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Patent number: 12140653Abstract: The invention relates to a method of Dixon-type MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to provide a method that enables an improved Dixon water/fat separation in combination with a dual-acquisition gradient-echo imaging sequence.Type: GrantFiled: September 11, 2020Date of Patent: November 12, 2024Assignee: Koninklijke Philips N.V.Inventor: Holger Eggers
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Patent number: 12127847Abstract: An apparatus for non-invasive evaluations and in-vivo diagnostics includes an open magnet, an RF antenna, and an NMR analytics logical circuit communicatively coupled to the RF antenna, wherein the open magnet is shaped to generate a static magnetic field that extends unilaterally into an object or internal organ of a subject when the open magnet is positioned against or in proximity to the object or subject, the static and RF magnetic fields shaped to generate a sensitive volume within a target region. The RF antenna or antenna array is configured to transmit RF pulses into the target region of the object or internal organ and receive sets of NMR signals generated by hydrogen or other elements, and the NMR analytics logical circuit is configured to obtain and analyze sets of NMR signals.Type: GrantFiled: December 29, 2022Date of Patent: October 29, 2024Assignee: Livivos Inc.Inventor: Pablo Jose Prado
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Patent number: 12125127Abstract: An imaging processing method that acquires first and second overlapping image data sets by performing first and second measurements on an overlapping location at first and second times, wherein the first and second times are different times; determines whether the first and second overlapping image data sets have substantially a same image quality; and generating and outputting, a first weighted overlapping combined image by combining (a) first weighted image data generated by applying a first weight to an overlapping frequency range of the overlapping image data set having a higher image quality and (b) second weighted image data generated by applying a second weight to the overlapping frequency range of the overlapping image data set having a lower image quality, wherein the first weight is larger than the second weight.Type: GrantFiled: November 29, 2021Date of Patent: October 22, 2024Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventor: Hassan Haji-Valizadeh