To Obtain Localized Resonance Within A Sample Patents (Class 324/309)
  • Patent number: 10809336
    Abstract: A method is for adapting a parameter of a parameter set for a magnetic resonance measurement of an examination object. An embodiment of the method includes choosing a parameter set required for the magnetic resonance measurement of the examination object; determining at least one interaction indicator applicable to an interaction between electromagnetic radiation and a tissue of the examination object; comparing the interaction indicator with a previously defined upper limit for the interaction indicator and, upon the upper limit being exceeded, determining a group of parameters from the parameter set, adaptable with a view to complying with the upper limit. The method further includes calculating a modification suggestion for a multiplicity of parameters from the group with a view to complying with the upper limit, identifying a parameter to optimize a quality parameter of the magnetic resonance measurement, and adapting the identified parameter in accordance with its modification suggestion.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: October 20, 2020
    Assignee: SIEMENS HEALTHCARE GMBH
    Inventor: Stefan Meyer
  • Patent number: 10809341
    Abstract: An apparatus and method are provided to correct motion artifacts in magnetic resonance imaging (MRI) data by obtaining magnetic resonance imaging (MRI) data, the MRI data including imaging segments and corresponding navigator segments, each imaging segment sampled over a respective regions of two or more regions of a k-space grid, one of the navigator segments being selected as a reference navigator segment; generating, for each imaging segment of the imaging segments, a respective phase map based on the reference navigator segment and a corresponding navigator segment of the each imaging segment; applying the respective phase maps to the corresponding imaging segments to generate corrected imaging segments; averaging the corrected imaging segments in k-space to generate averaged imaging segments; and reconstructing an MRI image based on the averaged imaging segments.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: October 20, 2020
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Anuj Sharma, Andrew J. Wheaton
  • Patent number: 10809212
    Abstract: A nuclear magnetic resonance method of analysis for glycosaminoglycans in general, and of heparins and low molecular weight heparins and their derivatives in particular, is provided. The method allows for their identification and for relative quantification of respective characteristic signals by 1H-NMR and/or 1H-13C HSQC.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: October 20, 2020
    Assignee: LABORATORIOS FARMACÉUTICOS ROVI, S.A.
    Inventors: Guillermo Franco Rodriguez, Ibon Gutierro Aduriz
  • Patent number: 10809329
    Abstract: A magnetic resonance imaging apparatus according to a present embodiment includes a gradient magnetic field coil and a gradient magnetic field power supply. The gradient magnetic field coil applies gradient magnetic field to an object, the gradient magnetic field coil including a plurality of channels. The gradient magnetic field power supply calculates a required power for each channel, and distributes maximum power to a channel requiring higher power than the required power of other channels with priority to the other channels, the maximum power being a limit value of total power to be supplied to the channels as a whole.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: October 20, 2020
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Motohiro Miura, Masashi Hori, Sho Kawajiri
  • Patent number: 10801964
    Abstract: The present invention relates to a method of determining the age of a body fluid stain in a sample. This method involves providing the sample containing a body fluid stain; providing a statistical model for determination of the age of the body fluid stain in the sample; subjecting the sample or an area of the sample containing the stain to a spectroscopic analysis to produce a spectroscopic signature for the sample; and applying the spectroscopic signature for the sample to the statistical model to ascertain the age of the body fluid stain in the sample. A method of establishing a statistical model for determination of the age of a body fluid stain in a sample is also disclosed.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: October 13, 2020
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventor: Igor K. Lednev
  • Patent number: 10801941
    Abstract: An isotope nuclear magnetic method for analyzing ineffective water absorption of rock pores includes steps of: saturating core pores of a core sample with a wetting phase fluid of water H2O, and obtaining a core T2 spectrum after being saturated with the water; re-saturating the core pores with a wetting phase fluid of heavy water D2O, and obtaining a rock baseline T2 spectrum; injecting fluorinated oil into the core sample saturated with the heavy water; injecting the water H2O, simulating a water injection process, and injecting the fluorinated oil, so as to analyze a content of immobile water and obtain a residual T2 spectrum, wherein a range formed by a difference between the residual T2 spectrum and the rock baseline T2 spectrum is an ineffective water absorption portion of the rock pores, and an ineffective water absorption amount is obtained.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: October 13, 2020
    Assignee: China University of Petroleum (East China)
    Inventors: Mingming Tang, Shuangfang Lu, Huifang Ma, Yang Gao, Shunwei Wu, Jing Zhang, Haisheng Hu, Wenbiao Huang, Jiafan Tang, Min Wang, Jijun Li, Xueping Liu, Hongkun Tan, Changhong Chu
  • Patent number: 10803631
    Abstract: A method for magnetic resonance imaging may include acquiring first k-space data that is generated by entering acquired magnetic resonance (MR) data into a plurality of first k-space locations. The method may further include synthesizing second k-space data for a plurality of second k-space locations that are not filled with the acquired MR data. The method may further include reconstructing an image from the first k-space data and the second k-space data by applying a reconstruction algorithm. The reconstruction algorithm is based at least in part on a neural network technique.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: October 13, 2020
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Guobin Li, Nan Liu, Jinguang Zong, Xiaoqian Huang, Shu Liao
  • Patent number: 10791995
    Abstract: In one embodiment, a magnetic resonance imaging apparatus configured to sequentially execute plural imaging sequences includes: processing circuitry configured to calculate a predicted value of Long MR Examination specific absorbed energy which is an accumulated SAR (Specific Absorption Ratio) value over the plural imaging sequences; and a display configured to display information on the predicted value with respect to a predetermined safety reference value of the Long MR Examination specific absorbed energy.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: October 6, 2020
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Kazuya Tanoue, Takao Kasugai, Shinya Ozawa
  • Patent number: 10794972
    Abstract: The disclosure relates to a local coil as well as a system including a magnetic resonance tomography system with a local coil. The local coil includes a data source and a signal output in signal communication with the data source for outputting data from the data source. The data source is configured to transmit a plurality of data items via the signal output. To this end, the signal output includes a radio-frequency source and a modulator and is configured to modulate to transmit the data from the data source onto a carrier frequency of the radio-frequency source by the modulator.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: October 6, 2020
    Assignee: Siemens Healthcare GmbH
    Inventor: Stephan Biber
  • Patent number: 10794976
    Abstract: A method of employing a central computer database (18) for supporting a characterization of tissue by magnetic resonance fingerprinting measurements, includes: exciting nuclei of a subject of interest by applying (50) a radio frequency excitation field B1 generated according to a magnetic resonance fingerprinting sequence (38), acquiring (52) magnetic resonance imaging signal data from radiation emitted by excited nuclei of the subject of interest, transferring (54) a magnetic resonance fingerprinting data set (42) to the central computer database (18), retrieving (56) a predefined dictionary from the central computer database (18), matching (60) the acquired magnetic resonance imaging signal data to the retrieved dictionary by applying a pattern recognition algorithm to determine a value (40) or a set of values (40) for at least one physical quantity (T1, T2), adding (62) at least the determined value (40) or the determined set of values (40) as a new entry of an associated medical data set (36) to the centr
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: October 6, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Thomas Erik Amthor, Sascha Krueger, Mariya Ivanova Donevea, Peter Koken, Julien Senegas, Jochen Keupp, Peter Boernert
  • Patent number: 10789683
    Abstract: The current application relates to an optimization procedure where the noise reduction strength is incrementally increased and applied in the noise reduction scheme. A non-linear quantitative map is then computed followed by the quantitative bias estimation. The optimization conditions are then checked and the noise reduction “strength” is increased if the bias difference is higher than a predefined threshold.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: September 29, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Raz Carmi, Galit Sarit Kafri
  • Patent number: 10788559
    Abstract: The invention provides for an instrument (100, 300) comprising: a radio-frequency antenna (102) comprising multiple antenna elements (104); a radio-frequency system (106) comprising independent receive channels for receiving a radio-frequency signal (140) from each of the multiple antenna elements; a memory (130) containing machine executable instructions (160, 162); and a processor (124) for controlling the instrument.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: September 29, 2020
    Assignee: Koninklijke Philips N.V.
    Inventor: Oliver Lips
  • Patent number: 10789740
    Abstract: Methods are provided for magnetic resonance (MR) image reconstruction. In one exemplary method, a low-resolution prescan MR data record is recorded, the prescan MR data record is adjusted to a provided form of a higher resolution scan MR data record which is likewise to be recorded, a compressed prescan MR data record is generated by geometric coil compression, the scan MR data record is recorded, a compressed scan MR data record is generated by geometric coil compression, and the compressed scan MR data record is then corrected by the compressed prescan MR data record. An MR system includes an MR coil arrangement configured to generate static and high-frequency magnetic fields at the site of an object to be examined and to detect response signals output by the object, and a data processing device configured to process data of the object generated from the response signals, wherein the data processing device is embodied to carry out the method.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: September 29, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Thomas Benkert, Marcel Dominik Nickel
  • Patent number: 10788555
    Abstract: A magnetic resonance imaging (MRI) system is provided that is controlled by a computer. The computer is programmed to control a plurality of gradient coils and radio frequency (RF) system of the MRI system to perform at least one pulse sequence that includes applying RF energy at least at two frequencies to manipulate exchangeable magnetization from protons in a subject. The computer is also programmed to control the plurality of gradient coils and RF system to acquire imaging data including magnetization transfer information from the exchangeable magnetization from protons in the subject in response to the pulse sequence. The computer is further programmed to, using frequency information associated with the imaging data, generate a report pertaining to inhomogeneous magnetization transfer occurring in the subject in response to the pulse sequence.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: September 29, 2020
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: David Alsop, Gopal Varma
  • Patent number: 10782255
    Abstract: This invention provides a NMR multi-dimensional method for measuring coupling constants within several coupling networks. At first, a 90° hard pulse was performed to flip the magnetization from the Z axis to the XY plane. After t1/2, a selective 180° pulse is implemented with a simultaneous Z-direction gradient, thus reversing different protons at different slices. Then the PSYCHE element is implemented. After another t1/2, the gradient G1 and Gp are implemented. At last, the EPSI readout is used to simultaneously record both the chemical-shift and the spatial information. As a result, from different specific slices, we can extract the scalar couplings between the proton reversed at this slice and other protons. These couplings lead to splittings in the indirect dimension, from which relevant coupling constants can be measured.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: September 22, 2020
    Assignee: XIAMEN UNIVERSITY
    Inventors: Yanqin Lin, Qing Zeng, Jinyong Chen, Zhong Chen
  • Patent number: 10782377
    Abstract: In a magnetic resonance method and apparatus for generating diffusion-weighted image data, at least two recordings are implemented in which raw data are acquired at raw data points of a raw data memory weighted with a b-value. The raw data memory has a first subregion and a second subregion, the first subregion being more than half of the total raw data points of the raw data memory. In each of the at least two recordings of the first subregion, full sampling takes place, and the second subregion is differently undersampled in the respective recordings. The raw data are combined and reconstructed into image data weighted with the b-value.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: September 22, 2020
    Assignee: Siemens Healthcare GmbH
    Inventor: Mario Zeller
  • Patent number: 10782381
    Abstract: A nuclear magnetic measuring device includes a measuring device having a control unit, a generator unit, a receiving unit, and a measuring signal path with an excitation signal path and a reaction signal path. A first switch is arranged such that, in a first state, the generator unit is connected to the excitation signal path and, in a second state, it is connected to a bypass signal path. A second switch is arranged such that, in the first state, the receiving unit is connected to the reaction signal path and, in a second state, it is connected to the bypass signal path. The control unit (i) controls the switches such that a part of the measuring signal path is bypassed, (ii) generates a test excitation signal, (iii) receives a test reaction signal, and (iv) determines an unstable property of the measuring signal path using the test excitation and reaction signals.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: September 22, 2020
    Assignee: KROHNE AG
    Inventors: Facundo Picco, Luciano Martin Carletti
  • Patent number: 10782376
    Abstract: Methods and apparatus for acquiring diffusion-weighted images. The method comprises selecting a plurality of diffusion gradient vectors, wherein at least two of the plurality of diffusion gradient vectors correspond to different non-zero b-values. The method further comprises determining a gradient strength for each of the plurality of diffusion gradient vectors such that an echo image time (TE) remains constant when gradients corresponding to each of the plurality of diffusion gradient vectors are applied. The method further comprises acquiring the diffusion-weighted images using a gradient encoding scheme including the gradients corresponding to each of the plurality of gradient vectors.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: September 22, 2020
    Assignee: Children's Medical Center Corporation
    Inventors: Simon K. Warfield, Benoit Scherrer
  • Patent number: 10775467
    Abstract: In a method and magnetic resonance (MR) apparatus for echo-planar MR imaging with which MR signals are entered in raw-data space with a zigzag-type trajectory, a sequence of readout gradients and phase-encoding gradients is applied such that a zigzag-type undersampled trajectory in raw-data space is filled, such that with the signal echoes being shifted by up to a quarter of the acquired raw-data space in the direction of the readout axis. Image data are reconstructed using a parallel-imaging reconstruction algorithm that operates on the raw data acquired in the zigzag-type trajectory, based on an interlaced Fourier transform.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: September 15, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Robin Heidemann, Patrick Liebig
  • Patent number: 10775466
    Abstract: A system for magnetic resonance imaging an object via a stochastic optimization of a sampling function is provided. The system includes a magnet assembly and a controller. The magnet assembly is operative to acquire MR data from the object. The controller is operative to: acquire a first MR data set using the magnet assembly; select the sampling function from a plurality of sampling function candidates based at least in part on the stochastic optimization; and acquire a second MR data set from the object using the magnet assembly based at least in part on the sampling function.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: September 15, 2020
    Assignee: GE PRECISION HEALTHCARE LLC
    Inventors: Suchandrima Banerjee, Enhao Gong, Greg Zaharchuk, John Pauly
  • Patent number: 10765395
    Abstract: One embodiment, a medical imaging diagnosis apparatus includes a gantry, a bed and a processing circuitry. The gantry acquires data. The bed supports a table top such that the table top is horizontally and vertically movable relative to a floor surface. The processing circuitry determines a lift route of the table top from an initial height to a target height to be either a first route or a second route. The first route is in which the table top is vertically lifted relative to the floor surface from the initial height to the target height. The second route is in which the table top is vertically lifted, while being horizontally moved, relative to the floor surface from the initial height to the target height.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: September 8, 2020
    Assignee: Canon Medical Systems Corporation
    Inventors: Keisuke Oishi, Hiroki Osaki
  • Patent number: 10768252
    Abstract: Various methods and systems are provided for acquiring k-space data for magnetic resonance imaging. In one example, after applying a phase encoding gradient, the k-space data of a phase angle is acquired while applying a frequency encoding gradient. An amplitude of the phase encoding gradient and a duration of the phase encoding gradient determined based on each and every of a phase angle of the phase encoding line and a duration of the frequency encoding gradient.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: September 8, 2020
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Lisha Nie, Yongchuan Lai, Xuan Liu
  • Patent number: 10765340
    Abstract: An imaging system includes a magnetic resonance imaging device and a radiation generator that are mechanically linked to each other such that both surround a patient bore for receiving and positioning the examination subject. The magnetic resonance imaging device has at least one main magnet for generating a magnetic field, and the radiation generator has a radiation source for generating radiation. The imaging system is configured from a static part and a part that is rotatable through an angle of rotation such that at least one rotatable main magnet is rotatable around a static radiation generation unit or a rotatable radiation generation unit is rotatable around at least one static main magnet. The imaging system includes at least two passive shim units, of which at least one static shim unit is stationary and at least one rotatable shim unit is fixedly connected to the rotatable part.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: September 8, 2020
    Assignee: Siemens Healthcare GmbH
    Inventor: Martino Leghissa
  • Patent number: 10765349
    Abstract: Provided is a technique for calculating an oxygen extraction fraction by using MRI where the oxygen extraction fraction in a brain including brain parenchyma is calculated via a simple processing without an impact on an examinee, such as administration of caffeine. For this purpose, an MRI apparatus of the present invention measures a complex image of nuclear magnetic resonance signals, and calculates from thus measured complex image, a physical property distribution for obtaining a physical property image reflecting the oxygen extraction fraction. Then, thus calculated physical property distribution is separated into tissue-specific physical property distributions for at least two tissues (separated tissue images). After converting any of the separated tissue images into the oxygen extraction fraction, a distribution of the oxygen extraction fraction is estimated based on the condition that a value of any selected pixel is substantially equal to a mean value of pixels surrounding the selected pixel.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: September 8, 2020
    Assignee: HITACHI, LTD.
    Inventors: Toru Shirai, Ryota Satoh, Yo Taniguchi, Hisaaki Ochi, Yoshihisa Sotome, Yoshitaka Bito, Takenori Murase
  • Patent number: 10769823
    Abstract: An image processing apparatus according to an embodiment includes a processing circuitry. The processing circuitry obtains an MR image acquired by a magnetic resonance imaging apparatus and related to a brain. The processing circuitry divides a region of the brain in the MR image, into plural regions. The processing circuitry sets a parameter value used in generation of a calculated image generated by synthetic MRI and related to the brain, such that a relation of contrast among regions included in the plural regions becomes a predetermined relation. The processing circuitry generates the calculated image by the synthetic MRI, by using the MR image and the parameter value.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: September 8, 2020
    Assignee: Canon Medical Systems Corporation
    Inventors: Takuma Igarashi, Ryo Shiroishi
  • Patent number: 10761168
    Abstract: A method for the simultaneous recording of magnetic resonance data relating to an examination subject from at least two different slices by a magnetic resonance sequence, wherein an excitation period of the magnetic resonance sequence that includes at least one sub-section that acts on only one of the slices, and that contains at least one high frequency pulse is used, wherein, to correct the main magnetic field inhomogeneities of the first order, for each slice affected by a sub-section, a correction parameter that modifies the gradient pulses that are to be emitted is determined, taking into account at least one main magnetic field map that describes the spatial distribution of the main magnetic field and a slice position of the affected slice and is applied in the emission of gradient pulses for the respective slice in the sub-section.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: September 1, 2020
    Assignee: Siemens Healthcare GmbH
    Inventor: Mario Zeller
  • Patent number: 10761166
    Abstract: A guide map is created for use in placing a spectroscopic single voxel in a region of interest in single voxel magnetic resonance spectroscopy. An anatomical planning image of the region of interest is obtained through MRI. As a spectroscopy voxel is stepped across the region of interest, characteristics of the magnetic field used in the MRI are measured at each location of the imaging voxel, and a guide-FWHM map indicative of the homogeneity/inhomogeneity of the magnetic field over the region of interest is derived using the measurements. The guide map is created by overlaying the guide-FWHM map on the anatomical planning image. A spectroscopic single voxel of a size corresponding to that of the spectroscopy voxel is placed within the region of interest as per the guide map. Then spectral data is acquired from the region of interest confined to the single voxel.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: September 1, 2020
    Assignee: Koninklijke Philips N.V.
    Inventor: Ivan Dimitrov
  • Patent number: 10761167
    Abstract: A method for creating a dictionary for a magnetic resonance fingerprinting (MRF) reconstruction includes training a semi-supervised learning system based on at least a set of MRF data and a set of control variables and generating a plurality of signal evolutions using the trained semi-supervised learning system. The method also includes generating an MRF dictionary using the plurality of signal evolutions generated using the trained semi-supervised learning system and storing the MRF dictionary in a memory. In one embodiment, the semi-supervised learning system is a MRF generative adversarial network (GAN).
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: September 1, 2020
    Assignee: Case Western Reserve University
    Inventors: Mark A. Griswold, Mingrui Yang
  • Patent number: 10761164
    Abstract: A method for generating a spatially resolved magnetic resonance dataset using a coil arrangement includes providing at least one correction datum based on receiver characteristics of the coil arrangement. The method also includes providing a magnetic resonance dataset with spatially resolved signal intensity data, and correcting the at least one signal intensity datum in the magnetic resonance dataset by the correction datum before or after providing the magnetic resonance dataset.
    Type: Grant
    Filed: April 28, 2018
    Date of Patent: September 1, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Marc Beckmann, Petra Bildhauer, Carsten Großhauser, Hubertus Fischer, Uvo Hölscher, Ralf Kartäusch, Jürgen Nistler, Dominik Paul, Dieter Ritter, Volker Weißenberger
  • Patent number: 10761155
    Abstract: In order to reduce the memory footprint used for monitoring specific absorption rate (SAR) in a magnetic resonance imaging (MRI) system, a hybrid sliding window method is provided. The method includes receiving a measured value once every first time interval, processing the measured value, and storing a value resulting from the processing in a first memory element. Measured values stored in second memory elements are summed every second time interval, where the first time interval is less than the second time interval. A representation of SAR is calculated every first time interval based on the value resulting from the processing and the sum of the measured values of the second memory elements. When the second time interval is reached, the value stored in the first memory element is moved to one of the second memory elements, and the value stored in the first memory element is reset to zero.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: September 1, 2020
    Assignee: Siemens Aktiengesellschaft
    Inventors: Holger Adolf, Thomas Benner, Jörg Ulrich Fontius, Rene Gumbrecht
  • Patent number: 10753991
    Abstract: Parallel transmit Magnetic Resonance MR scanner used to image a conductive object such as an interventional device like a guidewire within a subject. This is achieved by determining which Radio Frequency RF transmission modes produced by the parallel RF transmission elements couple with the conductive object and then transmitting at significantly reduced power so as to prevent excessive heating of the conductive object to an extent that would damage the surrounding tissue of the subject, for example, the coupling RF transmission modes may be generated at less than 30%, preferably around 10% of the normal power levels that would conventionally be used for MR imaging. However, even at these low power levels sufficient electric currents are induced in the conductive device to cause detectable MR signals; the location of the conductive object within the subject can thus be visualised.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: August 25, 2020
    Assignee: King's College London
    Inventors: Shaihan Malik, Francesco Padormo, Joseph Hajnal, Felipe Godinez
  • Patent number: 10750989
    Abstract: Systems and methods for noninvasively determining the function capacity of the kidney are provided. In the methods, first contrast agent is injected into the vasculature of a subject. The contrast agent is to be bound with functioning glomeruli of the kidney of the subject. Then, the kidney is imaged with a magnetic resonance imaging (MRI) system to acquire MRI images of the kidney. In the images, signal magnitudes or phases of voxels of regions bound with the contrast agent are different from signal magnitudes or phases of voxels of regions not bound with the contrast agent. Afterwards, the function capacity of the kidney is determined using the MRI images. Lastly, a report of the function capacity of the kidney is generated.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: August 25, 2020
    Assignee: Nephrodiagnostics LLC
    Inventors: Kevin Michael Bennett, Scott Charles Beeman
  • Patent number: 10753995
    Abstract: Systems and methods for simultaneous radio frequency (“RF”) transmission and reception for nuclear magnetic resonance applications, such as magnetic resonance imaging (“MRI”) are described. The system includes a simultaneous transmit and receive (“STAR”) control system that compensates for the effects of load changes in a radio frequency (“RF”) coil due to the inevitable motion of living subjects (e.g., from subject motion, respiration, swallowing). The system also maintains a high transmit-receive isolation, even when scanning a subject using a continuous RF broad band sweep excitation.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: August 25, 2020
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Sung Min Sohn, Djaudat S. Idiytullin, J. Thomas Vaughan, Michael Garwood
  • Patent number: 10746831
    Abstract: Described here are systems and methods for reconstructing images of a subject using a magnetic resonance imaging (“MRI”) system. As part of the reconstruction, synthesized data are estimated at arbitrarily specified k-space locations from measured data at known k-space locations. In general, the synthesized data is estimated using a convolution operation that is based on measured or estimated covariances in the acquired data. The systems and methods described here can thus be referred to as Convolution Operations for Data Estimation from Covariance (“CODEC”).
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: August 18, 2020
    Assignee: Dignity Health
    Inventor: James G. Pipe
  • Patent number: 10746833
    Abstract: A magnetic resonance vessel wall imaging method and device. The method comprises: applying a set pulse sequence into an imaging region, wherein the set pulse sequence comprises, in chronological order, a Delay Alternating with Nutation for Tailored Excitation (DANTE) pulse train, a variable flip angle train of a three-dimensional fast spin echo (SPACE), and a flip-down pulse train (S110); acquiring a magnetic resonance signal generated in the imaging region, and reconstructing a magnetic resonance images of the vessel wall in the imaging region according to the magnetic resonance signal (S120). By adding the flip-down pulse train behind the variable flip angle train of the three-dimensional fast spin echo (SPACE), the cerebrospinal fluid signals of the whole brain can be further suppressed effectively and uniformly, and the DANTE pulse train promotes the vessel wall imaging of the head and neck jointing portion.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: August 18, 2020
    Assignee: SHENZHEN INSTITUTES ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
    Inventors: Lei Zhang, Yiu-Cho Chung, Xin Liu, Xiaoqing Hu, Hairong Zheng
  • Patent number: 10739431
    Abstract: A magnetic resonance examination system is provided with a graphical user interface and an (software) analysis module. The analysis module is configured to analyze examination information, notably a selected examination protocol, for actions to be taken by the operator, such as connecting auxiliary equipment or radio frequency receiver coils to the magnetic resonance examination system. The analysis module supplies the actions to be taken to the (graphical) user interface at the proper instant before or during carrying-out the examination protocol. In this way the operator is guided and supported in the performance of the selected examination protocol. This improves the efficiency of workflow in performing one or more selected protocols. Preferably, the graphical user interface is provided inside the examination room and may be mounted on the gantry.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: August 11, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Paul Augustinus Peter Kaufholz, Marius Johannes Van Meel, Rudolf Theodoor Springorum, Willem Christiaan Constantijn Furster, Peter Van Der Meulen, Vincent Paul Quinten Van Wijk
  • Patent number: 10739432
    Abstract: Dynamic magnetic resonance imaging methods and devices are provided. According to an example, a method includes: collecting respective k-space data for each of imaging phases by scanning a part of a subject via an equidistant undersampling manner, determining basic k-space data for the part of the subject, determining respective differential k-space data for each of the imaging phases based on the respective k-space data for each of the imaging phases and the basic k-space data, obtaining a basic image based on the basic k-space data, determining a respective sparse image for each of the imaging phases, reconstructing a respective differential image for each of the imaging phases from the respective differential k-space data for the imaging phase, and obtaining a respective magnetic resonance image for each of the imaging phases based on the respective differential image for the imaging phase and the basic image.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: August 11, 2020
    Assignee: Shanghai Neusoft Medical Technology Co., Ltd.
    Inventor: Feng Huang
  • Patent number: 10739420
    Abstract: Systems and methods for mapping the transmit sensitivity of one or more radio frequency (“RF”) coils for use in magnetic resonance imaging (“MRI”) are described. The transmit RF field (“B1+”) for an RF coil, or an array of RF coils, is mapped using a robust, motion-insensitive technique that implements Bloch-Siegert shifts performed with interleaved positive and negative off-resonance shifts. The motion insensitivity of this technique makes it particularly useful for applications where there is significant motion, such as cardiac imaging, in which previous B1+ mapping techniques are not as accurate or effective.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: August 11, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Patent number: 10739429
    Abstract: The invention relates to a system for performing echo-planar spectroscopic imaging. The system comprises an acquisition unit for acquiring magnetic resonance data, wherein the acquisition unit is adapted to use a first encoding gradient in a readout direction and a second encoding gradient in a phase-encoding direction, wherein the first encoding gradient and the second encoding gradient are stepped. The system further comprises a reconstruction unit for reconstructing a magnetic resonance image based on the acquired magnetic resonance data.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: August 11, 2020
    Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
    Inventors: David Porter, Marco Vicari
  • Patent number: 10739425
    Abstract: According to one embodiment, an RF coil apparatus includes coil elements and multiplexing circuitry. The coil elements each receive magnetic resonance signals. The multiplexing circuitry multiplexes the magnetic resonance signals received respectively by the coil elements, by using a local signal. The multiplexing circuitry includes mixer circuitry and matching circuitry. The mixer circuitry has a local port for inputting the local signal that includes a local frequency. The mixer circuitry converts at least one frequency among the magnetic resonance signals in accordance with the local frequency of the local signal input via the local port. The matching circuitry matches, in a narrow band, a local signal that is to be input to the local port with the local frequency.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: August 11, 2020
    Assignee: Canon Medical Systems Corporation
    Inventors: Hisao Miyake, Yuji Takano
  • Patent number: 10732236
    Abstract: In a magnetic resonance (MR) apparatus and an operating method therefor, MR data are acquired from a patient using an MR sequence wherein, after at least one excitation pulse, multiple refocusing pulses are radiated during a readout period. The respective strengths of the refocusing pulses proceed according to a first flip-angle variation over time that is defined so as to minimize the SAR of the patient. A multislice imaging technique is used for simultaneous excitation and readout of at least two slices of a slice group of the patient, and flip-angle variations, which differ from the first variation, are selected in order to further reduce the SAR of the patient, compared with the use of identical flip-angle variations.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: August 4, 2020
    Assignee: Siemens Healtcare GmbH
    Inventor: Mario Zeller
  • Patent number: 10732217
    Abstract: Techniques are disclosed for carrying out ferromagnetic resonance (FMR) testing on whole wafers populated with one or more buried magnetic layers. The techniques can be used to verify or troubleshoot processes for forming the buried magnetic layers, without requiring the wafer to be broken. The techniques can also be used to distinguish one magnetic layer from others in the same stack, based on a unique frequency response of that layer. One example methodology includes moving a wafer proximate to a waveguide (within 500 microns, but without shorting), energizing a DC magnetic field near the target measurement point, applying an RF input signal through the waveguide, collecting resonance spectra of the frequency response of the waveguide, and decomposing the resonance spectra into magnetic properties of the target layer. One or both of the DC magnetic field and RF input signal can be swept to generate a robust set of resonance spectra.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: August 4, 2020
    Assignee: Intel Corporation
    Inventors: Kevin P. O'Brien, Kaan Oguz, Christopher J. Wiegand, Mark L. Doczy, Brian S. Doyle, MD Tofizur Rahman, Oleg Golonzka, Tahir Ghani
  • Patent number: 10732248
    Abstract: Some implementations provide a system that includes: a housing having a bore in which a subject to be image is placed; a main magnet configured to generate a volume of magnetic field within the bore, the volume of magnetic field having inhomogeneity below a defined threshold; one or more gradient coils configured to linearly vary the volume of magnetic field as a function of spatial location; one or more pulse generating coils configured to generate and apply radio frequency (RF) pulses to the volume of magnetic field in sequence to scan the portion of the subject; one or more shim gradient coils configured to perturb a spatial distribution of the linearly varying volume of magnetic field; and a control unit configured to operate the gradient coils, pulse generating coils, and shim gradient coils such that only the user-defined region within the volume of magnetic field is imaged.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: August 4, 2020
    Assignee: Synaptive Medical (Barbados) Inc.
    Inventors: Jeff Alan Stainsby, Chad Tyler Harris
  • Patent number: 10722151
    Abstract: A magnetic resonance device includes a radiofrequency unit that includes a radiofrequency antenna, at least one radiofrequency line and at least one radiofrequency injection point. Radiofrequency signals are transferred to the radiofrequency antenna by the at least one radiofrequency line and are coupled into the radiofrequency antenna at the at least one radiofrequency injection point. The magnetic resonance device also includes a patient receiving zone that is at least partially enclosed by the radiofrequency antenna, and a motion detection unit for detecting a movement of a patient that may be positioned within the patient receiving zone. At least one radiofrequency line includes at least one injection element by which at least one motion detection signal of the motion detection unit is coupled into the radiofrequency line.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: July 28, 2020
    Assignee: Siemens Aktiengesellschaft
    Inventors: Stephan Biber, Andreas Fackelmeier, Klaus Huber, Robert Rehner
  • Patent number: 10724975
    Abstract: Nuclear magnetic resonance (NMR) methods and apparatus are provided for investigating a sample utilizing NMR pulse sequences having solid state and CPMG pulse sequence portions. Various embodiments of solid state pulse sequences may be utilized including two-dimensional (repetitive) line-narrowing sequences. The hydrogen content of a solid portion of the sample may be determined by using one or more echoes resulting from the solid state sequence portion of the pulse sequence to establish a total organic hydrogen content of the sample, and by using a CPMG echo train to establish a fluid organic hydrogen content, and by subtracting one from the other to obtain the hydrogen content of the sample's solid portion. Additionally, or alternatively, the T2 values obtained from the line-narrowing and CPMG pulse sequences can be compared by plotting to obtain information regarding a characteristic of the sample. The NMR pulse sequence may also include a T1 portion.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: July 28, 2020
    Assignee: Schlumberger Technology Corporation
    Inventors: Ravinath Kausik Kadayam Viswanathan, Yiqiao Song
  • Patent number: 10726872
    Abstract: Systems and methods provide for advanced video editing techniques using sampling patterns. In one example, a computing device can receive a selection of a clip of a video and a sampling pattern. The computing device can determine a respective number of frames to sample from the clip for each interval of time over a length of time for a new clip. For example, the computing device can determine a function corresponding the pattern that relates time and the number of frames to sample, a histogram corresponding to the pattern, or a definite integral corresponding to the pattern, among other approaches. The computing device can extract these numbers of frames from the clip and generate the new clip from the extracted frames. The computing device can present the new clip as a preview and send the new clip to other computing devices.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: July 28, 2020
    Assignee: Snap Inc.
    Inventors: Nathan Kenneth Boyd, Devin Doty
  • Patent number: 10724974
    Abstract: The present invention generally relates to a method of using NMR relaxation rates (R2) of water molecules as an indicator of the extent of aggregation of biopharmaceutical formulations. The biopharmaceutical can be evaluated nondestructively without the vial or container being opened or protective seal compromised (i.e., broken). The method is applicable to all biopharmaceuticals and the water signal obtained by magnetic resonance relaxometry is very strong and sensitive because water is used as the solvent and is present in high (>90%) concentrations in every biopharmaceutical formulation.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: July 28, 2020
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Yihua Bruce Yu, Marc Taraban, Yue Feng
  • Patent number: 10722137
    Abstract: Aspects of the present disclosure relate to magnetic resonance thermometry. In one embodiment, a method includes acquiring undersampled magnetic resonance data associated with an area of interest of a subject receiving focused ultrasound treatment, and reconstructing images corresponding to the area of interest based on the acquired magnetic resonance data, where the reconstructing uses Kalman filtering.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: July 28, 2020
    Assignee: University of Virginia Patent Foundation
    Inventors: Samuel Fielden, Li Zhao, Wilson Miller, Xue Feng, Max Wintermark, Kim Butts Pauly, Craig H. Meyer
  • Patent number: 10725132
    Abstract: In a magnetic resonance (MR) apparatus, and model-based method, for identifying a nuclear spin-dependent attribute of a subject, MR signals are acquired in multiple repetitions of an MR data acquisition sequence that is changed from repetition-to-repetition so as to deliberately encode effects of magnetization transfer between nuclear spins into the acquired MR signals. A model is generated, composed of at least two molecule pools, in which a single magnetization transfer parameter is used that is derived from the MR signals in which the magnetization transfer is encoded. A nuclear spin-dependent attribute of the subject is then identified, by comparing at least one MR signal evolution from the subject to at least one signal evolution produced by the model.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: July 28, 2020
    Assignees: Siemens Healthcare GmbH, New York University
    Inventors: Martijn Cloos, Tom Hilbert, Tobias Kober
  • Patent number: 10718844
    Abstract: In a method and magnetic resonance (MR) apparatus for avoiding artifacts in scan data recorded by execution of a spin-echo sequence, an excitation pulse is radiated, at least one refocusing pulse is radiated, and at least one echo signal is read out. Following the radiation of the excitation pulse and before the readout of the at least one echo signal, at least two artifact-avoidance gradients with different amplitudes are activated, wherein the moments of the artifact-avoidance gradients balance each other.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: July 21, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Dominik Paul, Mario Zeller