To Obtain Localized Resonance Within A Sample Patents (Class 324/309)
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Patent number: 12196831Abstract: Methods and systems perform magnetic resonance fingerprinting (MRF) by obtaining magnetic resonance data over a main field-of-view (FOV) and resulting from providing a magnetic resonance fingerprinting pulse sequence to a sample. The pulse sequence includes gradient waveforms and radio frequency (RF) pulses that have pulse sequence parameters specifically tailored for scanning, not the entire main FOV but rather a reduced portion of that main FOV. The methods and systems further include comparing the magnetic resonance data from the sample to a fingerprint dictionary of signal profiles that specifically correspond to the reduced portion of the main FOV and generating tissue property maps that correspond only to that reduced portion.Type: GrantFiled: November 18, 2022Date of Patent: January 14, 2025Assignee: REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Vikas Gulani, Nicole Seiberlich, Jon-Fredrik Nielsen, Yun Jiang
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Patent number: 12196832Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an MRF scoring module (122). The MRF scoring module is configured for outputting an MRF quality score (126) in response to receiving MRF data (124) as input. The medical system further comprises a computational system (106) configured for controlling the medical system, wherein execution of the machine executable instructions causes the computational system to: receive (200) the MRF data; receive (202) the MRF quality score in response to inputting the MRF data into an MRF scoring module; append (206) the MRF quality score to the MRF data if the MRF quality score is within a predetermined range (128); and provide (208) a signal (132) if the MRF quality score is outside of the predetermined range.Type: GrantFiled: July 1, 2021Date of Patent: January 14, 2025Assignee: Koninklijke Philips N.V.Inventors: Thomas Erik Amthor, Mariya Ivanova Doneva, Peter Koken, Kay Nehrke
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Patent number: 12196827Abstract: The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.Type: GrantFiled: June 2, 2021Date of Patent: January 14, 2025Assignee: Universiteit TwenteInventors: Melissa Mathilde van de Loosdrecht, Hendrikus Johannes Gradus Krooshoop, Bernard ten Haken, Lejla Alic
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Patent number: 12196833Abstract: Systems and methods for generative adversarial networks (GANs) to remove artifacts from undersampled magnetic resonance (MR) images are described. The process of training the GAN can include providing undersampled 3D MR images to the generator model, providing the generated example and a real example to the discriminator model, applying adversarial loss, L2 loss, and structural similarity index measure loss to the generator model based on a classification output by the discriminator model, and repeating until the generator model has been trained to remove the artifacts from the undersampled 3D MR images. At runtime, the trained generator model of the GAN can be generate artifact-free images or parameter maps from undersampled MRI data of a patient.Type: GrantFiled: May 19, 2021Date of Patent: January 14, 2025Assignees: Siemens Healthineers AG, The Regents of the University of CaliforniaInventors: Peng Hu, Xiaodong Zhong, Chang Gao, Valid Ghodrati
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Patent number: 12198232Abstract: A method is for acquiring a magnetic resonance (MR) image dataset of at least two slices via simultaneous multi-slice excitation. An embodiment of the method includes executing an MR imaging sequence using multi-band radio-frequency excitation pulses to excite the at least two slices simultaneously in at least two repetitions, the repetitions each being executed according to a phase modulation scheme in which each of the simultaneously excited slices is assigned a phase and the phase of at least one of the simultaneously excited slices is changed from one repetition to the next, thereby acquiring an MR dataset of a collapsed image in each repetition; performing a spatial registration between the at least two collapsed images and performing motion correction on at least one of the MR datasets of the collapsed images; and reconstructing MR images of the at least two slices from the corrected MR datasets of the collapsed images.Type: GrantFiled: October 14, 2021Date of Patent: January 14, 2025Assignee: SIEMENS HEALTHINEERS AGInventors: Mario Zeller, Dominik Paul, Wei Liu
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Patent number: 12196829Abstract: A resonance circuit includes: an inductor formed along a surface of a first cylindrical form having a central axis; and a capacitor formed along a surface of a second cylindrical form having the central axis, wherein the inductor and the capacitor are electrically connected to each other to form a closed loop.Type: GrantFiled: December 22, 2022Date of Patent: January 14, 2025Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Konami Izumi, Yutaka Fujii, Yu Suzuki
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Patent number: 12193803Abstract: The present disclosure is related to systems and methods for magnetic resonance imaging (MRI). The method includes obtaining a plurality of target sets of k-space data by filling target MR signals acquired by a plurality of coils of an MRI device into k-space along a corkscrew trajectory. The method includes obtaining a coil sensitivity of each of the plurality of coils. The method includes obtaining a point spread function corresponding to the corkscrew trajectory. The method includes generating a target image based on an objective function.Type: GrantFiled: June 24, 2021Date of Patent: January 14, 2025Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Jingyuan Lyu, Yongquan Ye
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Patent number: 12196828Abstract: Methods and systems perform magnetic resonance fingerprinting (MRF) that provides tissue characterization through simultaneous quantification of water tissue properties and proton density fat fraction (PDFF), by using water-only and fat-only images from MRF. MRF is performed using rosette trajectories scanning k-space to effectively isolate water tissue and fat tissue, by separating these rosette trajectories into individual segments that are then analyzed to enable signals from fat tissue to be distinguished from water.Type: GrantFiled: November 18, 2022Date of Patent: January 14, 2025Assignee: REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Nicole Seiberlich, Yun Jiang, Jesse Hamilton, Yuchi Liu
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Patent number: 12196824Abstract: A medical system is provided with: a medical device that is inserted inside a living body; a distal end electrode that is disposed at a distal end of the medical device, and passes a high frequency to the living body from inside the living body; a magnetic sensor that is disposed outside the living body, and detects a magnetic field generated by the high frequency that has been passed from the distal end electrode to the living body; and an image generation portion that generates an internal image of the living body using magnetic field information output from the magnetic sensor.Type: GrantFiled: December 9, 2022Date of Patent: January 14, 2025Assignee: ASAHI INTECC CO., LTD.Inventor: Fumiyoshi Oshima
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Patent number: 12186067Abstract: A method may include obtaining a plurality of imaging signals collected by applying a wave encoding gradient to a region of interest (ROI) of a subject. The method may also include obtaining a plurality of auxiliary signals associated with the ROI. The method may also include obtaining a point spread function corresponding to the wave encoding gradient. The method may also include determining, based on the plurality of auxiliary signals, temporal information relating to at least one temporal dimension of the ROI. The method may also include determining, based on the plurality of auxiliary signals, the plurality of imaging signals, and the point spread function, spatial information relating to at least one spatial dimension of the ROI. The method may also include generating at least one target image of the ROI based on the temporal information and the spatial information.Type: GrantFiled: December 23, 2021Date of Patent: January 7, 2025Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Jingyuan Lyu, Qi Liu, Yongquan Ye, Jian Xu, Zhongqi Zhang
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Patent number: 12188900Abstract: Embodiments of the present invention relate to a system and method for performing temperature-dependent measurements of a magnetic nanoparticle sample. The system includes high frequency coils and sample temperature tunable assembly to determine the specific relaxation process for magnetic nanoparticle sample using both time and frequency domain techniques. During the temperature-dependent measurements of a magnetic nanoparticle sample, system in accordance with embodiments of the present invention resolve the nanoparticle dynamics using a temperature-tunable dual mode, AC susceptibility and magnetic relaxometry, to cover a broad range of frequencies and time scales. Other operational modes of the invention can drive the nanoparticles with arbitrary waveforms (sinusoidal, sum of sinusoids, or repeated pulses) to elicit and measure tailored response behavior from the magnetic nanoparticle sample.Type: GrantFiled: February 11, 2022Date of Patent: January 7, 2025Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCEInventors: Thinh Quoc Bui, Solomon Isaac Woods, Weston Leo Tew, Jr.
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Patent number: 12186105Abstract: A subject information acquisition apparatus, comprises: a signal generation unit configured to generate a high-frequency signal corresponding to each of the frequencies; an acquisition unit configured to acquire a plurality of detection signals based on at least one of a reflection signal and a transmission signal; a signal selection unit configured to select at least one detection signal from the plurality of detection signals based on an index value of the plurality of detection signals; a coupling amount detecting unit configured to detect a coupling amount of near-field coupling due to an electric field between the antenna and the subject based on a detection signal; and a displacement detecting unit configured to generate a displacement signal indicating a displacement of the subject based on the coupling amount.Type: GrantFiled: December 7, 2021Date of Patent: January 7, 2025Assignees: CANON KABUSHIKI KAISHA, CANON MEDICAL SYSTEMS CORPORATIONInventors: Ryuichi Nanaumi, Kazuya Okamoto, Takafumi Ohishi
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Patent number: 12186104Abstract: The devices, systems, and methods can improve magnetic resonance imaging (MRI), MR spectroscopy (MRS), MR spectroscopic imaging (MRSI) measurement(s), thereby providing more reliable quantification. The method may include a method for correcting MR image(s)/spectrum. The method may include providing an inhomogeneity field/response map of a region of interest; and providing MR image(s)/spectrum of the region of interest. The method may include determining an intravoxel/voxel inhomogeneity correction coefficient for each voxel of at least one subregion of the region of the interest using the inhomogeneity field/response map. The method may include correcting each voxel of the MR image(s)/spectrum of the region of interest using the intravoxel/voxel inhomogeneity correction coefficient.Type: GrantFiled: June 30, 2020Date of Patent: January 7, 2025Assignee: Emory UniversityInventor: Phillip Zhe Sun
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Patent number: 12189009Abstract: In a method for determining at least one test position for a test measurement to be recorded by means of a magnetic resonance system, a test image is recorded, and at least one test position is selected based on the test image. With methods for the compensation of effects of deviations of gradients actually generated during a readout duration from gradients planned for this readout time duration, the selection of test positions according to the disclosure based on a test image advantageously ensures that the test positions lie in a recording region favorable for the test measurement, e.g. also within an examination object to be examined in the test image. A higher image quality in MR images, which were generated using test measurements carried out at test positions positioned according to the disclosure, can therefore be achieved.Type: GrantFiled: September 29, 2022Date of Patent: January 7, 2025Assignee: Siemens Healthineers AGInventors: Mario Zeller, Adam Kettinger
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Patent number: 12189004Abstract: Accurate measurement of gradient waveform errors can often improve image quality in sequences with time varying readout and excitation waveforms. Self-encoding or offset-slice method sequences are commonly used to measure gradient waveforms. However, the self-encoding method requires a long scan time, while the offset-slice method is often low precision, requiring the thickness of the excited slice to be small compared to the maximal k-space encoded by the test waveform. This disclosure describes a novel hybrid of those methods, referred to as variable-prephasing (VP). Like the offset-slice method, VP uses the change in signal phase from offset-slices to calculate the gradient waveform. Similar to the self-encoding method, repeated acquisitions with a variable amplitude self-encoding gradient mitigates the signal loss due to phase wrapping, which, in-turn, allows thicker slices and greater SNR.Type: GrantFiled: February 3, 2023Date of Patent: January 7, 2025Assignee: Vanderbilt UniversityInventors: Kevin Harkins, Mark D. Does
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Patent number: 12181551Abstract: The present invention discloses a magnetic resonance fingerprinting imaging method with variable number of echoes, in addition to conventional MRF coding such as changing the excitation pulse angle, the method also introduces the change of the number of echoes, so that quantitative maps of B0, B1+, T1 and T2* can be obtained in a single scan. Further, if the echo time corresponding to the in-phase, opposed-phase and in-phase of water and fat is set for three consecutive echoes, the present invention can also image water and fat, and achieve the accurate quantification of B0, B1+, T1w, T1F, [T2*]w and [T2*]F. Through in vivo experiments and simulations, the effectiveness of the present invention has been proved. Therefore, the present invention can provide multiple information representations for common brain diseases (glioma) and fatty diseases (such as lipoma, fatty liver, etc.), which is conducive to clinical diagnosis and treatment.Type: GrantFiled: November 18, 2022Date of Patent: December 31, 2024Assignee: ZHEJIANG UNIVERSITYInventors: Huihui Ye, Jinmin Xu, Huafeng Liu
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Patent number: 12181549Abstract: A method for determining a B0 map for, for example, performing an imaging magnetic resonance measurement using a magnetic resonance apparatus, includes measuring an original magnetic field distribution in a measurement volume of the magnetic resonance apparatus, and computing a final B0 map that describes a magnetic field distribution produced in the measurement volume of the magnetic resonance apparatus by setting a shim state. The magnetic field distribution produced in the measurement volume of the magnetic resonance apparatus by setting the shim state differs from the original magnetic field distribution.Type: GrantFiled: December 1, 2022Date of Patent: December 31, 2024Assignee: Siemens Healthineers AGInventors: David Grodzki, Dieter Ritter, Armin Nagel, Christian Eisen
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Patent number: 12179033Abstract: A method to guide a targeted neurostimulation to the brain of a patient. Neuroimaging data is sensed from the brain of the patient. A processor is used to evaluate the neuroimaging data in order to calculate result data for a modeled functional measure of a particular brain network which defines a first brain region and a second brain region. A target location is determined in the first brain region based upon the result data and a functional connection measure between first and second brain region. A transcranial magnetic stimulator is adjusted to provide a magnetic stimulation signal for stimulation of the target location.Type: GrantFiled: September 12, 2023Date of Patent: December 31, 2024Inventor: Michael Sasha John
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Patent number: 12178562Abstract: A method for performing a magnetic resonance measurement of a patient using a magnetic resonance apparatus is provided. The magnetic resonance apparatus includes a radiofrequency antenna unit for producing an excitation pulse. A first B0 field map for a first motion state of the patient, and a second B0 field map for a second motion state of the patient are provided. A first excitation pulse for the first motion state, and a second excitation pulse for the second motion state are determined based on the first B0 field map and the second B0 field map. A magnetic resonance measurement is performed, during which the motion state of the patient is monitored. When the patient is in the first motion state, the radiofrequency antenna unit transmits the first excitation pulse. When the patient is in the second motion state, the radiofrequency antenna unit transmits the second excitation pulse.Type: GrantFiled: March 17, 2022Date of Patent: December 31, 2024Assignee: Siemens Healthineers AGInventors: David Grodzki, Dieter Ritter
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Patent number: 12171541Abstract: A magnetic resonance imaging apparatus includes sequence controlling circuitry configured: to obtain, during a time period after excitation of a first nuclide in a hyperpolarized state but no later than before obtainment of a first magnetic resonance signal from the first nuclide, a second magnetic resonance signal from a second nuclide that is different from the first nuclide and is in a non-hyperpolarized state, by exciting the second nuclide; and to control each of gradient magnetic field waveforms so as to cause both a first sum indicating a sum of application amounts of a gradient magnetic field related to the excitation of the second nuclide and a second sum indicating a sum of application amounts of a gradient magnetic field related to the obtainment of the second magnetic resonance signal to be close to zero, no later than before the obtainment of the first magnetic resonance signal.Type: GrantFiled: February 8, 2023Date of Patent: December 24, 2024Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Ryohei Takayanagi, Takaya Mori, Kagami Fujita, Akihiro Taguchi, Masao Yui
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Patent number: 12164012Abstract: A magnetic resonance (MR) system compensation interface having: a hardware subinterface configured to receive individual hardware parameters from an individual scan unit of an MR system; a model determination unit configured to determine an imperfection model on the basis of the hardware parameters; a compensation model determination unit configured to determine a compensation model on the basis of the imperfection model; an application subinterface configured to receive application data assigned to an application; and a compensation unit configured to determine compensated application data on the basis of the received application data and the determined compensation model.Type: GrantFiled: December 8, 2022Date of Patent: December 10, 2024Assignee: Siemens Healthineers AGInventors: Uvo Hölscher, Christoph Forman, Peter Gall
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Patent number: 12164014Abstract: A method for measuring concomitant fields in a magnetic resonance (MR) system is provided. The method includes applying a measurement pulse sequence in a plurality of acquisitions. Applying the measurement pulse sequence further includes applying a first bipolar gradient pulse in a first acquisition, applying a second bipolar gradient pulse in reverse polarities from the first bipolar gradient pulse in a second acquisition, and applying the measurement pulse sequence without a bipolar gradient pulse in a third acquisition. The method further includes acquiring MR signals emitted from the subject, and generating phase images based on the MR signals. The method also includes generating volumetric vector field maps based on the phase images, wherein the volumetric vector field maps include concomitant field at each spatial location in a 3D volume, the concomitant field represented as a vector. In addition, the method includes outputting the volumetric vector field maps.Type: GrantFiled: January 18, 2023Date of Patent: December 10, 2024Assignee: GE PRECISION HEALTHCARE LLCInventors: Seung-Kyun Lee, Afis Ajala
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Patent number: 12158512Abstract: A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity.Type: GrantFiled: January 19, 2023Date of Patent: December 3, 2024Assignee: TURING MEDICAL TECHNOLOGIES INC.Inventors: Chad Sylvester, Deanna Greene, Scott Marek, Scott Norris, Jarod Roland, Evan Gordon, Timothy Laumann, Damien Fair, Kenneth Bruener, Nico Dosenbach
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Patent number: 12153114Abstract: A method for 3D oscillating-gradient prepared gradient spin-echo imaging and a device. The imaging method comprises the following steps: first, using a global saturation module to destroy previous residual transverse magnetization; second, embedding a pair of trapezoidal cosine oscillating gradients into a 90°x-180°y-90°?x radiofrequency pulse by a diffusion encoding module, to separate diffusion encoding from signal acquisition; then, using a fat saturation module to suppress a fat signal; finally, acquiring a signal by means of gradient spin-echo readout, and correcting phase errors among multiple excitations by multiplexed sensitivity-encoding reconstruction. Compared with a 2D plane echo-based oscillating gradient diffusion sequence used on a 3T clinical system, a 3D oscillating-gradient prepared gradient spin-echo sequence effectively reduces the imaging time, improves the signal to noise ratio, and is beneficial to clinical transformation of time-dependent diffusion MRI technology.Type: GrantFiled: September 26, 2022Date of Patent: November 26, 2024Assignee: ZHEJIANG UNIVERSITYInventors: Dan Wu, Haotian Li, Yi Zhang
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Patent number: 12150747Abstract: Even when imaging is aborted, data collected so far is utilized in image reconstruction, thereby enhancing examination efficiency. A certain priority imaging data available for image reconstruction by a fast-imaging method is determined, when collecting k-space data according to a predetermined imaging method. If collection of the certain priority imaging data is completed when imaging is aborted, imaging reconstruction is executed using the priority imaging data. The priority imaging data is determined based on a relationship between the imaging method under execution, and the fast-imaging method underlying determination of the priority imaging data.Type: GrantFiled: June 1, 2021Date of Patent: November 26, 2024Assignee: FUJIFILM CORPORATIONInventor: Yusuke Hoshino
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Patent number: 12151125Abstract: Ultrasound transducers adjust the B1+ and/or B1? field distribution in an MRI apparatus to improve the signal sensitivity and homogeneity at a region of interest. Approaches employed include strategic placement of field-altering features such as slots and/or dipoles along the exterior surface or, in some cases, the interior of the transducer. In various embodiments, the field-altering features are (or behave as) passive resonators.Type: GrantFiled: June 5, 2020Date of Patent: November 26, 2024Assignee: INSIGHTEC LTD.Inventor: Boaz Shapira
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Patent number: 12153111Abstract: A method for magnetic resonance imaging performs chemical shift encoded imaging to produce complex dual-echo images which are then applied (with imaging parameters) as input to a deep neural network to produce as output water-only and fat-only images. The deep neural network can be trained with ground truth water/fat images derived from chemical shift encoded images using a conventional water-fat separation algorithm such as projected power approach, IDEAL, or VARPRO. The chemical shift encoded imaging comprises performing an image acquisition with the MRI scanner via a spoiled-gradient echo sequence or a spin-echo sequence.Type: GrantFiled: January 27, 2023Date of Patent: November 26, 2024Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Shreyas S. Vasanawala, Yan Wu
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Patent number: 12146932Abstract: A magnetic resonance imaging (MRI) system and method integrating multi-nuclide synchronous imaging and spectral imaging is provided. The MRI system includes a spectral imaging module, a multi-nuclide synchronous imaging module, and a spectral reconstruction and image fusion module, where the spectral imaging module is configured to acquire a spectrum of a nuclide Nuc; the multi-nuclide synchronous imaging module is configured to perform synchronous imaging of nuclides Nuc1 . . . Nucn, where when n=1, Nucl is 1H; and when n>1, Nucn is a non-1H nuclide; and the spectral reconstruction and image fusion module is configured to receive the spectrum of the nuclide Nuc and images of the nuclides Nuc1 . . . Nucn, and acquire spatial distribution information of compounds of the nuclide Nuc and spatial distribution information of the non-1H nuclide through fusion. The system and method can synchronously acquire MR signals of different nuclides, and reconstruct and fuse non-1H nuclide images.Type: GrantFiled: February 21, 2024Date of Patent: November 19, 2024Assignee: HARBIN MEDICAL UNIVERSITYInventors: Xilin Sun, Chunsheng Yang, Kai Wang, Yongyi Wu, Lijiao Wang, Lili Yang, Lina Wu
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Patent number: 12148160Abstract: This invention discloses a method for quantitatively measuring the water exchange rate across myelin sheath. The method involves the following steps: acquiring images using the FEXI sequence; identifying anisotropic regions and the orientation of neural fibers at each pixel within these regions; selecting images where the diffusion weighted directions are perpendicular to the orientation of neural fibers at each pixel within the anisotropic regions and numerically averaging the selected images; calculating the apparent exchange rate (AXR), the apparent diffusion coefficient (ADC), and the filter coefficient (?) using the numerically averaged images, where AXR serves as a specific parameter reflecting the water exchange rate across myelin sheath. The method provided by this invention enables specific detection of the exchange process of water molecules inside and outside the myelin sheath and analysis of the apparent water exchange rate across myelin sheath.Type: GrantFiled: December 6, 2022Date of Patent: November 19, 2024Assignee: ZHEJIANG UNIVERSITYInventors: Ruiliang Bai, Zhaoqing Li
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Patent number: 12138081Abstract: An asthma management system and method are disclosed for collecting environmental and individual health data to predict the onset of asthma symptoms to allow for preventative therapy tailored on an individual basis. In one embodiment a computer system is in electrical communication with an individual user interface and one or more environmental factor collection points via a communications network. The user interface is adapted to send and receive asthma-related data including asthma profile and real-time asthma status data to the computer system via the communication network, and the environmental factor collection points are adapted to send and receive data to the computer system via the communications network.Type: GrantFiled: June 16, 2020Date of Patent: November 12, 2024Assignee: CAIRE Diagnostics Inc.Inventors: Solomon Ssenyange, Ryan Leard, David Anvar, Brian Awabdy, Todd Smith, Vivek Balasubramanyam
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Patent number: 12143413Abstract: A system and method is described that sends multiple simulated phishing emails, text messages, and/or phone calls (e.g., via VoIP) varying the quantity, frequency, type, sophistication, and combination using machine learning algorithms or other forms of artificial intelligence. In some implementations, some or all messages (email, text messages, VoIP calls) in a campaign after the first simulated phishing email, text message, or call may be used to direct the user to open the first simulated phishing email or text message, or to open the latest simulated phishing email or text message. In some implementations, simulated phishing emails, text messages, or phone calls of a campaign may be intended to lure the user to perform a different requested action, such as selecting a hyperlink in an email or text message, or returning a voice call.Type: GrantFiled: August 28, 2022Date of Patent: November 12, 2024Assignee: KnowBe4, Inc.Inventors: Alin Irimie, Stu Sjouwerman, Greg Kras, Eric Sites
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Patent number: 12140653Abstract: The invention relates to a method of Dixon-type MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to provide a method that enables an improved Dixon water/fat separation in combination with a dual-acquisition gradient-echo imaging sequence.Type: GrantFiled: September 11, 2020Date of Patent: November 12, 2024Assignee: Koninklijke Philips N.V.Inventor: Holger Eggers
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Patent number: 12140655Abstract: A dynamic magnetic resonance angiography, MRA, method, comprising: acquiring, by an MR scanning device, a multi-contrast magnetic resonance, MR, sequence of a portion of a body; identifying, by a processing circuit, blood vessels of the portion by identifying blood of the portion based on predetermined characteristic of blood and the multi-contrast MR sequence; generating, by the processing circuit, a first MRA image frame and a second MRA image frame, based on the multi-contrast MR sequence, respectively visualising a first part and a second part of the identified blood vessels; generating, by the processing circuit, a dynamic MRA image for visualising a dynamic blood flow through a part of the portion, based on the first and second MRA image frame.Type: GrantFiled: April 15, 2020Date of Patent: November 12, 2024Assignee: SYNTHETICMR AB (PUBL)Inventor: Marcel Warntjes
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Patent number: 12127847Abstract: An apparatus for non-invasive evaluations and in-vivo diagnostics includes an open magnet, an RF antenna, and an NMR analytics logical circuit communicatively coupled to the RF antenna, wherein the open magnet is shaped to generate a static magnetic field that extends unilaterally into an object or internal organ of a subject when the open magnet is positioned against or in proximity to the object or subject, the static and RF magnetic fields shaped to generate a sensitive volume within a target region. The RF antenna or antenna array is configured to transmit RF pulses into the target region of the object or internal organ and receive sets of NMR signals generated by hydrogen or other elements, and the NMR analytics logical circuit is configured to obtain and analyze sets of NMR signals.Type: GrantFiled: December 29, 2022Date of Patent: October 29, 2024Assignee: Livivos Inc.Inventor: Pablo Jose Prado
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Patent number: 12125127Abstract: An imaging processing method that acquires first and second overlapping image data sets by performing first and second measurements on an overlapping location at first and second times, wherein the first and second times are different times; determines whether the first and second overlapping image data sets have substantially a same image quality; and generating and outputting, a first weighted overlapping combined image by combining (a) first weighted image data generated by applying a first weight to an overlapping frequency range of the overlapping image data set having a higher image quality and (b) second weighted image data generated by applying a second weight to the overlapping frequency range of the overlapping image data set having a lower image quality, wherein the first weight is larger than the second weight.Type: GrantFiled: November 29, 2021Date of Patent: October 22, 2024Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventor: Hassan Haji-Valizadeh
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Patent number: 12114967Abstract: A magnetic resonance (MR) system is provided. The MR system includes a gradient coil assembly and a concomitant field correction computing device. The at least one processor of the computing device is programmed to receive MR signals acquired with the MR system using a three-dimensional (3D) pulse sequence, wherein a kx dimension and a ky dimension in k-space are sampled along non-Cartesian trajectories. The at least one processor is further programmed to correct effects of concomitant fields generated by gradient fields applied by the gradient coil assembly by adjusting the MR signals with second-order concomitant phases accumulated from second-order concomitant fields, and reconstructing MR images based on the adjusted MR signals. The second-order concomitant phases vary as functions of time and spatial locations. The at least one processor is also programmed to output the MR images.Type: GrantFiled: January 18, 2023Date of Patent: October 15, 2024Assignee: GE PRECISION HEALTHCARE LLCInventors: Afis Ajala, Seung-Kyun Lee, Thomas Kwok-Fah Foo
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Patent number: 12117512Abstract: Systems and methods for providing improved eddy current correction (ECC) in medical imaging environments. One or more of the embodiments disclosed herein provide a deep learning-based convolutional neural network (CNN) model trained to automatically generate an ECC mask which may be composited with two-dimensional (2D) scan slices or four-dimensional (4D) scan slices and made viewable through, for example, a web application, and made manipulable through a user interface thereof.Type: GrantFiled: February 11, 2020Date of Patent: October 15, 2024Assignee: Arterys Inc.Inventors: Berk Dell Norman, Jesse Lieman-Sifry, Sean Patrick Sall, Daniel Irving Golden, Hok Kan Lau
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Patent number: 12111378Abstract: A method of operating a multi-coil magnetic resonance imaging system is disclosed which includes a controller performing a simulation using a predefined tissue model, determining output values of a variable of interest (VOI) associated with operation of two or more coils of an MRI system based on the simulation, comparing the simulated output values of the VOI to an a priori target values of the VOI, if the simulated output values of the VOI are outside of a predetermined envelope about the a priori target values of the VOI, then performing an optimization, wherein the optimization includes iteratively adjusting the circuit values until the simulated output values of the VOI are within the predetermined envelope about the a priori target values of the VOI thereby establishing VOI optimized values, and loading the established VOI optimized values and operating the magnetic resonance imaging system on the tissue to be imaged.Type: GrantFiled: July 3, 2023Date of Patent: October 8, 2024Assignee: Purdue Research FoundationInventors: Joseph V. Rispoli, Xin Li
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Patent number: 12111377Abstract: A method for creating multiple sequences of diffusion-weighted magnetic resonance (MR) images of an object is described, wherein each of said sequences of MR images represents the same series of contiguous cross-sectional slices covering a volume of the object.Type: GrantFiled: July 31, 2020Date of Patent: October 8, 2024Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e. V.Inventors: Jens Frahm, Dirk Voit, Oleksandr Kalentev
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Patent number: 12112407Abstract: An image generating apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to successively generate Magnetic Resonance (MR) images in a plurality of temporal phases by using a first reconstruction method. The processing circuitry is configured to determine a first temporal phase before MR images in all the temporal phases during a predetermined time period are generated. The processing circuitry is configured to generate an MR image in the first temporal phase determined by the determining unit, by using a second reconstruction method having a larger processing load than the first reconstruction method.Type: GrantFiled: May 25, 2021Date of Patent: October 8, 2024Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Kensuke Shinoda, Hideaki Kutsuna
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Patent number: 12105171Abstract: The disclosure relates to techniques for saturation band MRI scanning. The techniques include obtaining the position of a saturation band of the saturation band MRI, obtaining the position of the region of interest to be imaged, taking the direction from the saturation band to the region of interest as a first direction, determining the direction of the slice selection gradient, and starting saturation band MRI scanning.Type: GrantFiled: September 16, 2021Date of Patent: October 1, 2024Assignee: Siemens Healthineers AGInventor: Qiong Zhang
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Patent number: 12106402Abstract: For magnetic resonance (MR) reconstruction using artificial intelligence (AI), the AI-based reconstruction for MR imaging systems is offloaded to one or more servers. A remote server performs AI-based reconstruction. A library of recent, old, custom, and/or publicly available AI-based reconstruction processes may be rapidly deployed and available to the server, which has the memory and processing resources for AI-based reconstruction. Load balancing of the data and/or between servers may improve performance.Type: GrantFiled: October 6, 2021Date of Patent: October 1, 2024Assignee: Siemens Healthineers AGInventors: Nirmal Janardhanan, Laszlo Lazar, Boris Mailhe, Simon Arberet, Mariappan S. Nadar, Dorin Comaniciu, Kelvin Chow, Michael Bush
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Patent number: 12105170Abstract: A magnetic resonance imaging method, a magnetic resonance imaging system, and a computer-readable storage medium are provided. The magnetic resonance imaging method comprises: acquiring a plurality of portions of a k-space by using a plurality of sets of imaging sequences to obtain a plurality of k-space data sets, each set of imaging sequences comprising a pre-dephasing gradient pulse and a plurality of phase encoding gradients applied after the pre-dephasing gradient pulse, wherein the pre-dephasing gradient pulses in the plurality of sets of imaging sequences have a standard area difference in order when sorted according to the sizes of area values, and the standard area difference is 2/N of the area of any phase encoding gradient, where N is the number of sets of the plurality of sets of imaging sequences; respectively reconstructing a magnetic resonance image from each of the plurality of k-space data sets; and processing the plurality of k-space data sets to obtain a magnetic resonance image.Type: GrantFiled: November 17, 2022Date of Patent: October 1, 2024Assignee: GE Precision Healthcare LLCInventors: Lei Gao, Yongchuan Lai
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Patent number: 12105037Abstract: A method of detecting spins in a sample, includes exciting the spins of the sample by means of a radio-frequency or microwave electromagnetic pulse for flipping the spins, and detecting a noise signal produced by the return of the spins to equilibrium by means of a device for counting radio-frequency or microwave photons.Type: GrantFiled: March 22, 2021Date of Patent: October 1, 2024Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Patrice Bertet, Emmanuel Flurin
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Patent number: 12105172Abstract: A magnetic resonance tomography unit includes a magnet unit having a magnetic controller for generating a homogenous magnetic field. The magnetic controller is configured to change the homogenous magnetic field in a short, predetermined time within image acquisition of an object under examination, such that a Larmor frequency for a predetermined layer of the object under examination remains in a predetermined frequency range. A layer in the object under examination is selected and a value for the homogenous magnetic field, in which the Larmor frequencies of the nuclear spins of the layer lie in a predetermined frequency band, is determined by a control unit taking into account a predetermined magnetic field gradient. The established value for the homogenous magnetic field and the predetermined magnetic field gradient is set by the magnetic controller, and an excitation pulse, frequencies of which only lie in the predetermined frequency band, is emitted.Type: GrantFiled: March 30, 2022Date of Patent: October 1, 2024Assignee: Siemens Healthineers AGInventors: Georg Seegerer, Stephan Kannengießer, Rainer Schneider, Jürgen Nistler, Markus Vester
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Patent number: 12104967Abstract: One or more computing devices, systems, and/or methods are provided. In an example, a method includes tuning a sensor comprising a first resonator having an effective gain, a second resonator having an effective loss, and a coupling circuit connected between the first resonator and the second resonator at an extrema degeneracy point with a nonlinear response to a force applied to the sensor. At least one of the first resonator, the second resonator, or the coupling circuit comprises a variable capacitor having a capacitance that varies as a function of the force. The method comprises injecting an input signal into one of the first resonator or the second resonator, receiving an output signal from one of the first resonator or the second resonator, and determining a magnitude of a force based on a difference between a first frequency extrema point and a second frequency extrema point in the output signal.Type: GrantFiled: February 25, 2022Date of Patent: October 1, 2024Assignee: Wisconsin Alumni Research FoundationInventors: Ramathasan Thevamaran, Jizhe Cai, Tsampikos Kottos, Fred Ellis, Rodion Kononchuk
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Patent number: 12099105Abstract: Systems and methods are provided herein for determining whether to extend scanning performed by a magnetic resonance imaging (MRI) system. According to some embodiments, there is provided a method for imaging a subject using an MRI system, comprising: obtaining data for generating at least one magnetic resonance image of the subject by operating the MRI system in accordance with a first pulse sequence; prior to completing the obtaining the data in accordance with the first pulse sequence, determining to collect additional data to augment and/or replace at least some of the obtained data; determining a second pulse sequence to use for obtaining the additional data; and after completing the obtaining the data in accordance with the first pulse sequence, obtaining the additional data by operating the MRI system in accordance with the second pulse sequence.Type: GrantFiled: June 30, 2023Date of Patent: September 24, 2024Assignee: Hyperfine Operations, Inc.Inventors: Laura Sacolick, Carole Lazarus, Rafael O'Halloran, Hadrien A. Dyvorne
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Patent number: 12097020Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.Type: GrantFiled: March 27, 2023Date of Patent: September 24, 2024Assignee: ACLARION, INC.Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Ricardo Dario Pradenas
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Patent number: 12099103Abstract: Embodiments of the present application provide a radio frequency head coil (300), RE head coil. The RE head coil (300) comprises a coil former (310) comprising at least a first leg and a second leg arranged at a distance from each other to define a space there between, the coil former (310) being at least sectionally flexible and having at least one first fastening portion (315, 316) arranged adjacent to the space (314), and a respiratory mask (320) comprising a gas outlet (324) and at least one second fastening portion (322, 323), wherein in an operable condition in which the RE head coil (300) is adapted to be arranged at least in sections around a head of a patient (S) and in which the second fastening portion (322, 323) is adapted to be fastened to the first fastening portion (315, 316), the gas outlet (324) is disposed within the space (314).Type: GrantFiled: August 7, 2020Date of Patent: September 24, 2024Assignee: Koninklijke Philips N.V.Inventors: Christoph Gunther Leussler, Michael Gunter Helle, Daniel Wirtz, Gereon Vogtmeier, Steffen Weiss, Sunil Kumar Vuppala, Rajendra Singh Sisodia
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Patent number: 12097019Abstract: A magnetic resonance (MR) local coil and a magnetic resonance apparatus are disclosed. The MR local coil includes an antenna unit having at least one antenna for receiving and/or transmitting high frequency (HF) signals; a connection cable for connecting the MR local coil to a magnetic resonance apparatus; and a two-dimensional, (e.g., ribbon-shaped), transmission element for transmitting energy, (e.g., electrical energy), and/or signals, (e.g., electrical and/or optical signals), between the connection cable and the antenna unit. In this case, the transmission element is at least in part arranged about an axis of rotation in a spiral manner.Type: GrantFiled: September 19, 2022Date of Patent: September 24, 2024Assignee: Siemens Healthineers AGInventors: Daniel Driemel, Stephan Zink, Martin Hemmerlein