Using An Electron Resonance Spectrometer System Patents (Class 324/316)
-
Patent number: 8836331Abstract: The major object of the invention is to provide a volume-type hologram resin composition and a surface relief-type hologram resin composition having a high effect of preventing forgery and excellent in foil cutting, as well as a hologram layer and a hologram transfer foil using thereof. To achieve the object, there is provided a volume-type hologram resin composition having at least one kind of photopolymerizable compound, a photopolymerization initiator and fine particles, wherein the fine particles show magnetic resonance.Type: GrantFiled: August 15, 2011Date of Patent: September 16, 2014Assignee: Dai Nippon Printing Co., Ltd.Inventors: Hiroyuki Otaki, Kenji Ueda
-
Patent number: 8816685Abstract: A method and system for performing pulsed electron paramagnetic resonance is disclosed. In one aspect, the method includes generating an excitation pulse train for applying to an object having probes and detecting from the probes an echo response induced by the excitation pulse train.Type: GrantFiled: March 29, 2011Date of Patent: August 26, 2014Assignees: IMEC, Pepric nvInventors: Peter Vaes, Stephanie Teughels
-
Publication number: 20140218032Abstract: In some aspects, a resonator device for spin resonance applications is described. In some examples, the resonator device includes a substrate, terminals, and resonators. The terminals include a first terminal having first terminal segments disposed on a substrate surface, and a second terminal having second terminal segments disposed on the substrate surface opposite the first terminal segments. The resonators include conductors disposed on the substrate surface between the first and second terminals. Each conductor is disposed between one of the first terminal segments and a respective, opposite one of the second terminal segments.Type: ApplicationFiled: June 28, 2013Publication date: August 7, 2014Applicant: Quantum Valley Investment Fund LPInventors: Hamidreza Mohebbi, David G. Cory
-
Patent number: 8798949Abstract: A spectrometer has: Accumulation means to obtain a data set containing N data points, repeating the measurement M times to obtain M spectral data sets or time-domain data sets S1 (d1 to dN) to SM (d1 to dN), and accumulating the M spectral data sets or time-domain data sets. Means for creating sets S1 (dn) to SM (dn) of the data points contained in the M spectral data sets or time-domain data sets S1 (d1 to dN) to SM (d1 to dN). Correlation computing means for finding correlations. Computing means for finding either the product of an accumulated or anticipated spectrum.Type: GrantFiled: May 17, 2011Date of Patent: August 5, 2014Assignee: JEOL Resonance Inc.Inventors: Kiyonori Takegoshi, Yusuke Nishiyama
-
Publication number: 20140210473Abstract: An electron spin resonance spectrometer includes a bridge to transmit an excitation frequency and to receive a signal frequency; a probe electrically connected to the bridge and comprising: a first conductor in electrical communication with the bridge to transmit the signal frequency to the bridge; a shorting member electrically connected to the first conductor to transmit the excitation frequency to a sample, to produce the signal frequency, and to transmit the signal frequency to the first conductor; and a second conductor electrically connected to the shorting member; and a magnet disposed proximate to the probe.Type: ApplicationFiled: April 3, 2014Publication date: July 31, 2014Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGYInventors: JASON P. CAMPBELL, KIN P. CHEUNG, JASON T. RYAN, PATRICK M. LENAHAN
-
Publication number: 20140167754Abstract: Apparatus, methods, and other embodiments associated with nuclear magnetic resonance (NMR) fingerprinting using echo splitting are described. One example apparatus includes an NMR logic configured to repetitively and variably sample a (k, t, E) space associated with an object to acquire a set of NMR signals. Members of the set of NMR signals are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The varying parameters may include the number of echo splitting pulses, spacings between echo splitting pulses, flip angle of echo splitting pulses, echo time, RF amplitude, and other parameters. The NMR apparatus may also include a signal logic configured to produce an NMR signal evolution from the NMR signals, and a characterization logic configured to characterize a resonant species in the object as a result of comparing acquired signals to reference signals.Type: ApplicationFiled: September 12, 2013Publication date: June 19, 2014Applicant: Case Western Reserve UniversityInventors: Renate Jerecic, Mark Griswold, Yun Jiang, Dan Ma
-
Patent number: 8717025Abstract: In a method and system for echo planar imaging, after having applied a radiofrequency pulse and a slice selection gradient, continuous readout gradients alternating between positive and negative are applied and a phase encoding gradient is applied before starting each readout gradient. A slice selection gradient is applied at the same time as applying the phase encoding gradient. Scanning signals are collected during the duration of the readout gradients. Image reconstruction is implemented based on the scanning signals to obtain a scanned image.Type: GrantFiled: October 20, 2010Date of Patent: May 6, 2014Assignee: Siemens AktiengesellschaftInventor: De He Weng
-
Publication number: 20140097842Abstract: A method includes generating, from an integrated oscillator circuit, an oscillating output signal and generating, by an integrated power amplifier (PA) circuit, an amplified oscillating output signal based on the oscillating output signal. The method further includes receiving, by integrated receiver amplifier circuit, an electron spin resonance (ESR) signal from biological samples that include a magnetic species and generating, by the integrated receiver amplifier circuit, an amplified ESR signal based on the received ESR signal. The method further includes receiving, by the integrated receiver amplifier circuit, an electron spin resonance (ESR) signal from magnetic nanoparticles that are loaded with drugs or attached to human cells.Type: ApplicationFiled: September 30, 2013Publication date: April 10, 2014Applicant: William Marsh Rice UniversityInventors: Xuebei Yang, Charles Chen, Payam Seifi, Aydin Babakhani
-
Publication number: 20140097841Abstract: Systems and methods for spinwave-based metrology in accordance with embodiments of the disclosure involve generating and detecting spinwaves in a sample having a ferromagnetic material; and determining a material thickness, a material integrity measure, a presence of a manufacturing defect, a categorical type of manufacturing defect, and/or a manufacturing process statistic corresponding to spinwave behavior in the sample. In an embodiment, spinwaves are generated by way of concurrent exposure of a target measurement site of the sample to each of a bias magnetic field and radiation (e.g., microwave or radio frequency radiation) produced by a first set of integrated waveguides. A response signal corresponding to a behavior of spinwaves within the target measurement site can be generated by way of a second set of integrated waveguides.Type: ApplicationFiled: September 6, 2013Publication date: April 10, 2014Applicant: NATIONAL UNIVERSITY OF SINGAPOREInventors: Hyunsoo YANG, Sankha Subhra MUKHERJEE, Jae Hyun KWON
-
Patent number: 8674694Abstract: An apparatus and method for triaging patients according to radiation exposure operates by measuring electron paramagnetic resonance spectra of fingernails, toenails, and/or teeth. A coil structure allows in vivo measurement of tooth enamel or fingernail keratin with reduced coupling to underlying tissue.Type: GrantFiled: August 25, 2010Date of Patent: March 18, 2014Inventors: James S. Hyde, Jason W. Sidabras, Richard R. Mett
-
Patent number: 8664955Abstract: The present invention provides an apparatus and a corresponding method useful for electron paramagnetic resonance imaging, in situ and in vivo, using high-isolation transmit/receive (TX/RX) coils, which, in some embodiments, provide microenvironmental images that are representative of particular internal structures in the human body and spatially resolved images of tissue/cell protein signals responding to conditions (such as hypoxia) that show the temporal sequence of certain biological processes, and, in some embodiments, that distinguish malignant tissue from healthy tissue. In some embodiments, the TX/RX coils are in a surface, volume or surface-volume configuration.Type: GrantFiled: February 22, 2011Date of Patent: March 4, 2014Inventor: Howard J. Halpern
-
Patent number: 8653819Abstract: A method, system, apparatus, and computer readable medium has been provided with the ability to obtain a complex permittivity ? or a complex permeability ? of a sample in a cavity. One or more complex-valued resonance frequencies (fm) of the cavity, wherein each fm is a measurement, are obtained. Maxwell's equations are solved exactly for ?, and/or ?, using the fm as known quantities, thereby obtaining the ? and/or ? of the sample.Type: GrantFiled: September 2, 2010Date of Patent: February 18, 2014Assignee: California Institute of TechnologyInventors: Martin B. Barmatz, Henry W. Jackson
-
Patent number: 8648596Abstract: Described is an electron spin resonance (ESR) spectrometer comprising a miniaturized radio-frequency (RF) microwave cavity resonator. The miniaturized RF microwave cavity resonator receives a carrier signal from a circulator, modulates the signal path signal, and reflects the carrier signal back to the circulator to amplify the carrier signal prior to demodulation. A mixer receives and demodulates the carrier signal and outputs an audio signal to generate an ESR spectrum for analyzing a chemical composition of a fluid sample. The ESR spectrum represents a magnetic susceptibility of the fluid sample to a magnetic resonance cause variation in a resonant frequency of the miniaturized RF microwave cavity resonator. In a desired aspect, the carrier signal is split into two paths prior to demodulation. The two paths are demodulated by different mixers to produce two separate outputs, an absorption spectrum and a dispersion spectrum.Type: GrantFiled: October 18, 2010Date of Patent: February 11, 2014Assignee: Active Spectrum, Inc.Inventors: Colin T. Elliott, Christopher John White, James R. White
-
Patent number: 8643362Abstract: According to one embodiment, a apparatus includes a coil, a clock generator, an echo transmitter, a carrier generator, a clock transmitter, a regenerator, an receiver, a reconstructor, a detector, and a controller. The echo transmitter generates and transmits an echo transmission signal synchronously with a clock signal generated by the clock generator to wirelessly transmit an echo signal output from the col. The carrier generator generates a carrier signal have a frequency within a variable range. The clock transmitter wirelessly transmits a clock transmission signal. The regenerator regenerates the clock signal based on the transmitted clock transmission signal. The receiver extracts the echo signal synchronously with the regenerated clock signal from the transmitted echo transmission signal. The detector detects a frequency of an interference wave.Type: GrantFiled: March 15, 2011Date of Patent: February 4, 2014Assignee: Kabushiki Kaisha ToshibaInventors: Takahiro Sekiguchi, Koji Akita, Toshiyuki Nakanishi, Kazuya Okamoto, Sojuro Kato
-
Publication number: 20140021952Abstract: A microwave resonator device (1), being configured in particular for electron spin resonance measurements, comprises a resonator being resonant with first and second microwave field modes and including first and second resonance sections (7, 8) arranged along a longitudinal axis (2) of the resonator, and a coupling unit being arranged between the first and second resonance sections, wherein the coupling unit includes a conducting plate (16) being arranged on the longitudinal axis (2) and covering a central portion of a cross-sectional area of the resonator, the conducting plate (16) is adapted to adjust a first mode frequency of the first microwave field mode, and the conducting plate (16) is arranged at a field minimum of the second microwave field mode. Furthermore, a method of conducting an electron spin resonance measurement with a sample to be investigated is described.Type: ApplicationFiled: July 27, 2010Publication date: January 23, 2014Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e. V.Inventors: Igor Tkach, Marina Bennati
-
Publication number: 20140009159Abstract: A system and method involve performing electron paramagnetic resonance on an object under study. The system comprises a first field generator adapted for generating an orienting magnetic field for orienting the magnetization of the object under study and a second field generator adapted for generating RF excitation waves at a frequency to generate electron paramagnetic resonance (EPR) in the object under test. The system also comprises a detection unit adapted for detecting the EPR signals emitted by the object under test and a control unit adapted for controlling the relative orientation of the orienting magnetic field induced by the first field generator with respect to the detection unit. The system furthermore comprises a processing unit programmed for combining detected EPR signals obtained using different relative orientations of the orienting magnetic field with respect to the detection unit.Type: ApplicationFiled: March 21, 2012Publication date: January 9, 2014Applicant: PEPRIC NVInventors: Peter Vaes, Stephanie Teughels
-
Patent number: 8610434Abstract: In an electron paramagnetic resonance spectrometer, a closed cycle cryocooler is used to cool gaseous helium, which is then circulated around a sample to cool the sample by direct convection. Since the sample is not mechanically connected to the refrigerator, no vibrations are transmitted from the refrigerator to the sample and the sample can be quickly removed and replaced. The cooled helium can be passed through a Joule-Thomson expansion device before circulating the cooled helium around the sample to further cool the helium. In addition, a vacuum pump can be connected to the helium outlet after circulating the cooled helium around the sample to increase the pressure differential across the Joule-Thomson expansion device and further cool the helium. In order to raise the temperature of the cooled helium, a heater can be placed about the cooled helium line upstream from the sample.Type: GrantFiled: July 21, 2011Date of Patent: December 17, 2013Assignee: Coldedge Technologies, Inc.Inventors: Arthur H. Heiss, Ajay Khatri
-
Publication number: 20130285661Abstract: The invention relates to a spin detector arrangement for detecting vector components of a predominating spin vector in a particle beam (T) having a predominating spin orientation of the particles. The spin detector arrangement comprises a spin rotator (1) having a switchable coil (5), wherein the switchable coil (5) comprises an axial direction and is aligned such that the particle beam (T) passes through the switchable coil (5) along the axial direction; a deflection device (7) connected downstream of the spin rotator (1) and deflecting the path of the particle beam (T) electrostatically by a deflection angle; a spin detector (9) connected downstream of the deflection device (7), allowing the deflection of the vector component of the spin vector predominating in the particle beam (T) perpendicular to the direction of motion of the particle beam (T); and a switching unit (15) connected to the switchable coil (5), allowing switching of the excitation state of the coil (5).Type: ApplicationFiled: November 16, 2011Publication date: October 31, 2013Applicant: SPECS SURFACE NANO ANALYSIS GMBHInventor: Oliver Schaff
-
Patent number: 8564293Abstract: The invention relates to a method for changing spin relaxation, a method for detecting a spin current, and a spintronic device using spin relaxation, and spin relaxation is changed through injection of a spin current. A spin current 4 is injected into a material 1 in a certain spin state, so that the spin relaxation time can be controlled.Type: GrantFiled: March 14, 2008Date of Patent: October 22, 2013Assignee: Tohoku UniversityInventors: Kazuya Ando, Kazuya Harii, Kohei Sasage, Eiji Saitoh
-
Publication number: 20130271140Abstract: Example apparatus and methods order projections in a 3D MRI acquisition to achieve improved equidistant spacing or to achieve improved adherence to a target distribution. The equidistant or target spacing may exist in k-space and/or in kt-space. In one embodiment, the improved equidistant spacing is a substantially uniform spacing. The substantially uniform spacing may be achieved using a modification of a charge repulsion analysis that treats points of projections that intersect the surface of a 3D volume to be imaged as point charges distributed on the 3D volume. In another embodiment, the target spacing may be uniform, non-uniform, uniform in parts and non-uniform in other parts, and other combinations.Type: ApplicationFiled: April 13, 2012Publication date: October 17, 2013Applicant: Case Western Reserve UniversityInventors: Mark Griswold, Gregory R. Lee
-
Patent number: 8552724Abstract: A method for spin magnetic resonance applications in general, and for performing NMR (nuclear magnetic resonance spectroscopy) and MRI (nuclear magnetic resonance imaging) in particular is disclosed. It is a quantum theory-based continuous precision method. This method directly makes use of spin magnetic resonance random emissions to generate its auto-correlation function and power spectrum, from which are derived spin relaxation times and spin number density using strict mathematical and physical equations. This method substantially reduces the NMR/MRI equipment and data processing complexity, thereby making NMR/MRI machines less costly, less bulky, more accurate, and easier to operate than the pulsed NMR/MRI. By employing extremely low transverse RF magnetic B1 field, MRI with this method is much safer for patients. And, by employing continuous spin magnetic resonance emissions, NMR with this method is of virtually unlimited spectral resolution to satisfy any science and engineering requirements.Type: GrantFiled: February 11, 2010Date of Patent: October 8, 2013Inventor: Derek D. Feng
-
Publication number: 20130257431Abstract: Various systems and methods for detecting electron spins using electron paramagnetic resonance are described. An excitation signal generator configured to generate an excitation signal of varying amplitude and phase as compared to a reference signal may be present. A crossed-loop resonator configured to isolate a detection signal produced by the excitation signal exciting an object with a magnetic field may also be present. Further, a detection device configured to detect electron spins of the object using the detection signal isolated by the crossed-loop resonator may be present.Type: ApplicationFiled: March 7, 2013Publication date: October 3, 2013Inventor: Colorado Seminary, which owns and operates the University of Denver
-
Patent number: 8542014Abstract: A method and system are disclosed for gathering information about an object including single domain particles which have a diameter in the range of about 5 to 80 nm. In one aspect, a method includes generating a static magnetic field of less than about 0.1 Tesla on the object and generating an RF energy, pulsed or continuous wave, so as to generate electron paramagnetic resonance of the single domain particles. The method also includes detecting the electron paramagnetic resonance of the single domain particles in the form of an image of the object. The single domain particles may have a predetermined diameter and a predetermined saturation magnetization and the applied magnetic field may be such that the single domain particles reach a magnetization being at least about 10% of the saturation magnetization. The method may be used for detecting tags in an object and for activating tags.Type: GrantFiled: September 14, 2012Date of Patent: September 24, 2013Assignee: IMECInventors: Stephanie Teughels, Peter Vaes
-
Patent number: 8525516Abstract: This atomic clock comprises means for applying two mutually perpendicular oscillating magnetic fields (9, 10), governed by a control device (5) that makes them apply a static or nearly static magnetic field for compensating the ambient magnetic field in order to cancel sub-level energy variations of the matter, which disrupt the frequency of the returned photons and the reference provided by the clock. Traditional magnetic shielding may be omitted. Said device can also operate as a magnetometer.Type: GrantFiled: December 10, 2008Date of Patent: September 3, 2013Assignee: Commissariat à l'énergie atomique et aux énergies alternativesInventors: Matthieu Le Prado, Jean-Michel Leger
-
Patent number: 8508229Abstract: A magnetic resonance elastography (“MRE”) driver that can produce shear waves in a subject without relying on mode conversion of longitudinal waves is disclosed. More specifically, the MRE driver includes a pneumatic driver located remotely from a magnetic resonance imaging (“MRI”) system which is operable in response to an applied electrical current to oscillate, a pressure-activated driver that is positioned on a subject in the MRI system, and a tube that is in fluid communication, at one end, with the pneumatic driver. The pressure-activated driver includes a base plate and a driver plate having a region between them that receives the tube. Oscillations of the pneumatic driver produce a pressure wave in the tube that causes the driver plate to vibrate. The driver plate rests against the subject of interest to apply a corresponding shear oscillatory force to the subject during the MRE examination.Type: GrantFiled: July 30, 2010Date of Patent: August 13, 2013Assignee: MAYO Foundation for Medical Education and ResearchInventors: Eric C Ehman, Kiaran P McGee, Richard L Ehman
-
Publication number: 20130127466Abstract: A scanner for assessing localized oxygenation of a desired region of interest includes a handheld housing having a proximal end and a distal end. A resonator coil is disposed within the housing and also disposed adjacent the distal end of the housing. The resonator coil is configured to both excite and read paramagnetic materials. A magnet is disposed within the housing and also disposed adjacent the distal end of the housing. The magnet is configured to provide a substantially uniform magnetic field over the desired region of interest. The scanner is configured to use electron paramagnetic resonance to assess localized oxygenation in the desired region.Type: ApplicationFiled: May 25, 2012Publication date: May 23, 2013Applicant: 02 Insights, Inc.Inventors: Periannan Kuppusamy, Samit Kumar Gupta, Robert Lawrence Rushenberg
-
Publication number: 20130119986Abstract: The invention relates to a method for acquiring, by use of a continuous-wave electron spin resonance imaging scheme that sweeps a magnetic field, a 14N nitroxy radical distribution image and a 15N nitroxy radical distribution image in a single image capturing operation. This image acquiring method is characterized in that the central one (B) of three absorption peaks derived from 14N nitroxy radical is caused to move to a higher or lower magnetic field side and Fourier transform is used to determine a parameter (?), which represents the amplitude of the absorption peak of the higher or lower magnetic field side, and a parameter (?) which represents the peak position of that absorption peak.Type: ApplicationFiled: July 26, 2011Publication date: May 16, 2013Applicant: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventor: Hiroshi Hirata
-
Publication number: 20130093424Abstract: A resonator system for electron spin resonance (ESR) is disclosed. The resonator system comprises: a generally planar resonator layer defining an open-loop gapped by a non-conductive gap in the layer, and a microwave feed, positioned configured for transmitting microwave to the resonator layer such as to concentrate, with a quality factor of at least 100, a magnetic field within an effective volume of less than 1 nL above the layer.Type: ApplicationFiled: October 18, 2011Publication date: April 18, 2013Inventors: Aharon BLANK, Ygal TWIG
-
Patent number: 8421460Abstract: An upconverter has a two port parametric amplifier that has a first port to receive an input signal to be amplified and upconverted and a second port to receive a local oscillator signal and to output the amplified, upconverted signal at upper and lower sideband frequencies. The upconverter further has an antenna coupled to the second port to receive the local oscillator signal and transmit the amplified, upconverted signal at upper and lower sideband frequencies and a low noise amplifier at the first port of the parametric amplifier, which is powered by the local oscillator signal.Type: GrantFiled: March 18, 2010Date of Patent: April 16, 2013Assignee: Siemens AktiengesellschaftInventor: Anthony Peter Hulbert
-
Patent number: 8421461Abstract: A magnetic resonance imaging system upconverter stage has a number of local coils and a number of upconverters to receive a signal from an output of each coil. Each upconverter has a number of two port upconverter cores, each core having a first port to receive a signal from a local coil and a second port to output an upconverted signal at upper and lower sideband frequencies through an antenna coupled to the second port. The inputs of the plurality of upconverter cores are connected in parallel, and at least one antenna is associated with the second port of each core.Type: GrantFiled: April 2, 2010Date of Patent: April 16, 2013Assignee: Siemens AktiengesellschaftInventors: Peter Cork, Anthony Peter Hulbert
-
Patent number: 8415951Abstract: An upconverter has a two port parametric amplifier that has a first port to receive an input signal to be amplified and upconverted and a second port to receive a local oscillator signal and to output the amplified, upconverted signal at upper and lower sideband frequencies. The upconverter further has an antenna coupled to the second port and a power splitter inserted between the second port of the parametric amplifier and the antenna.Type: GrantFiled: March 18, 2010Date of Patent: April 9, 2013Assignee: Siemens AktiengesellschaftInventor: Markus Vester
-
Patent number: 8410778Abstract: In a magnetic resonance (MR) method and apparatus for the acquisition of a first image data set and a second image data set of an examination subject, a series of excitation pulses is radiated into the examination subject, and after each excitation pulse, a first echo signal is detected after a first echo time TE1 and a second echo signal is detected after a second echo time TE2, with TE2 greater than TE1, and the first echo signal is entered in a first raw MR data set and the second echo signal is entered in a second raw MR data set. A first image data set is acquired from the first MR data set on the basis of magnitude information contained in the first MR data set. A second image data set is acquired from the second MR data set on the basis of phase information contained in the second MR data set. The first and second image data sets are stored on at least one memory device.Type: GrantFiled: March 12, 2010Date of Patent: April 2, 2013Assignee: Siemens AktiengesellschaftInventors: Patrick Gross, Joerg Roland
-
Patent number: 8410776Abstract: An emission tomography detector module and an emission tomography scanner are disclosed. In at least one embodiment, the emission tomography detector modules includes a scintillator to capture an photon, the scintillator emitting a scintillating light on capturing the photon; a first type of solid-state photodetector to detect the scintillating light; and a second type of solid-state photodetector to detect the scintillating light, wherein the first type of solid-state photodetector and the second type of solid-state photodetector are different with respect to a detecting property.Type: GrantFiled: September 28, 2009Date of Patent: April 2, 2013Assignees: Siemens Medical Solutions USA, Inc., Siemens AktiengesellschaftInventors: Matthias J. Schmand, Markus Vester, Nan Zhang
-
Publication number: 20130021032Abstract: In an electron paramagnetic resonance spectrometer, a closed cycle cryocooler is used to cool gaseous helium, which is then circulated around a sample to cool the sample by direct convection. Since the sample is not mechanically connected to the refrigerator, no vibrations are transmitted from the refrigerator to the sample and the sample can be quickly removed and replaced. The cooled helium can be passed through a Joule-Thomson expansion device before circulating the cooled helium around the sample to further cool the helium. In addition, a vacuum pump can be connected to the helium outlet after circulating the cooled helium around the sample to increase the pressure differential across the Joule-Thomson expansion device and further cool the helium. In order to raise the temperature of the cooled helium, a heater can be placed about the cooled helium line upstream from the sample.Type: ApplicationFiled: July 21, 2011Publication date: January 24, 2013Applicant: COLDEDGE TECHNOLOGIES, INC.Inventors: Arthur H. HEISS, Ajay KHATRI
-
Publication number: 20130015857Abstract: A method and system are disclosed for gathering information about an object including single domain particles which have a diameter in the range of about 5 to 80 nm. In one aspect, a method includes generating a static magnetic field of less than about 0.1 Tesla on the object and generating an RF energy, pulsed or continuous wave, so as to generate electron paramagnetic resonance of the single domain particles. The method also includes detecting the electron paramagnetic resonance of the single domain particles in the form of an image of the object. The single domain particles may have a predetermined diameter and a predetermined saturation magnetization and the applied magnetic field may be such that the single domain particles reach a magnetization being at least about 10% of the saturation magnetization. The method may be used for detecting tags in an object and for activating tags.Type: ApplicationFiled: September 14, 2012Publication date: January 17, 2013Applicant: IMECInventors: Stephanie TEUGHELS, Peter Vaes
-
Publication number: 20120326722Abstract: Instrumentation and methodologies are provided that enable the direct measurement of free radicals generated in patients as a result of radiation therapy through the use of proton beams and other forms of ionizing radiation. As a result, in accordance with at least one disclosed embodiment, the instrumentation and methodologies may be used in conjunction with radiation therapy to detect, monitor and/or control generation of free radicals in cancerous tissue during such radiation therapy.Type: ApplicationFiled: May 18, 2012Publication date: December 27, 2012Applicant: WEINBERG MEDICAL PHYSICS LLCInventors: Irving N. WEINBERG, Stanley Thomas FRICKE
-
Patent number: 8334698Abstract: A sample holding device, adapted for holding a sample, like a rodent or an MR phantom sample in a magnet bore of a magnetic resonance tomography (MRT) device, comprises a sample carrier being adapted for an arrangement in the bore of the MRT device, wherein the sample carrier comprises a carrier platform for accommodating the sample and at least one clamping part with radial locking pieces being adapted for fixing the sample carrier in a hollow enclosure structure, wherein the at least one clamping part is connected with the carrier platform. Furthermore, an MRT device and a method of MRT imaging of a sample are described.Type: GrantFiled: August 1, 2007Date of Patent: December 18, 2012Assignees: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V., Biomedizinische NMR Forschungs GmbHInventors: Roland Tammer, Susann Boretius, Thomas Michaelis, Andreas Pucher-Diehl
-
Patent number: 8314740Abstract: A magnetic field focusing assembly includes a magnetic field generating device configured to generate a magnetic field, and a split ring resonator assembly configured to be magnetically coupled to the magnetic field generating device and configured to focus the magnetic field produced by the magnetic field generating device.Type: GrantFiled: May 20, 2009Date of Patent: November 20, 2012Assignee: DEKA Products Limited PartnershipInventor: David Blumberg, Jr.
-
Publication number: 20120262176Abstract: A method for determination of the images of electron relaxation times, T1, in EPR tomography consists in the resultant relaxation time, T1, established from the ratio of amplitudes of signals recorded for various scanning directions is found, whereupon a variability function of the resultant relaxation time, T1, is found for at least two different scan frequencies, whereupon projections for the respective relaxation times are established for every point of the recorded spectra by matching functions specific for the respective relaxation times to the resultant function of variability of relaxation time, and then images are reconstructed in 1D or in 2D or in 3D depend of the experimental conditions.Type: ApplicationFiled: March 22, 2012Publication date: October 18, 2012Applicant: POLITECHNIKA POZNANSKAInventors: Tomasz CZECHOWSKI, Mikolaj BARANOWSKI, Kazimierz JURGA, Jan JURGA, Wojciech CHLEWICKI, Piotr SZCZEPANIK, Piotr KEDZIA
-
Publication number: 20120265426Abstract: An instrument and method using electron spin resonance spectrometry for measuring the concentration of airborne soot particles, and the like, that includes continuously passing a sample of exhaust gas through a resonating RF microwave cavity resonator during the application therethrough of a uniform slowly varying uniform magnetic field that is rapidly modulated and measuring the resulting phase modulation or amplitude modulation thereof to derive an electron spin resonance signal that directly senses the concentration of carbon free radicals produced as a result of inefficient combustion of hydrocarbons during operation of the vehicle or boiler. A further invention is the use of this signal for feedback control of the engine or boiler operating parameters to minimize or substantially eliminate particulate matter emissions.Type: ApplicationFiled: June 25, 2012Publication date: October 18, 2012Inventors: James Robert White, Christopher John White, Colin T. Elliott, Alexander H. Slocum
-
Patent number: 8283926Abstract: A method and system are disclosed for gathering information about an object including single domain particles which have a diameter in the range of about 5 to 80 nm. In one aspect, a method includes generating a static magnetic field of less than about 0.1 Tesla on the object and generating an RF energy, pulsed or continuous wave, so as to generate electron paramagnetic resonance of the single domain particles. The method also includes detecting the electron paramagnetic resonance of the single domain particles in the form of an image of the object. The single domain particles may have a predetermined diameter and a predetermined saturation magnetization and the applied magnetic field may be such that the single domain particles reach a magnetization being at least about 10% of the saturation magnetization. The method may be used for detecting tags in an object and for activating tags.Type: GrantFiled: December 2, 2010Date of Patent: October 9, 2012Assignee: IMECInventors: Stephanie Teughels, Peter Vaes
-
Patent number: 8269496Abstract: An electron paramagnetic resonance imaging system that includes means for continuously irradiating a sample with RF irradiation; means for imposing on the sample a sinusoidally varying magnetic field along with rotating gradients for spatial encoding; means for directly detecting signal data from the sample, without using field modulation, while irradiating the sample with RF radiation continuously, the means for directly detecting having means for sweeping the sinusoidally varying magnetic field; and means for processing the signal data, using means including a digital signal processor.Type: GrantFiled: June 28, 2007Date of Patent: September 18, 2012Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human ServicesInventors: Sankaran Subramanian, Nallathamby Devasahayam, Janusz Koscielniak, James B. Mitchell, Murali Krishna Cherukuri
-
Patent number: 8237441Abstract: A method and an apparatus are disclosed for determining the effective count rate of photons in a combined MR/emission tomography recording.Type: GrantFiled: November 12, 2009Date of Patent: August 7, 2012Assignee: Siemens AktiengesellschaftInventors: Axel Martinez-Möller, Stephan Nekolla
-
Patent number: 8217657Abstract: A diplex filter is formed by two impedance-transforming filters with separate transmission frequency ranges and with separate cut-off frequency ranges and a connection node at which two series elements of the two filters are connected. These two series elements are each fashioned as a parallel oscillating circuit, each parallel oscillating circuit exhibiting a predetermined reactance in a midband of the respective transmission frequency range and a parallel resonance in a midband of the respective cut-off frequency range. The diplex filter can be realized in a simple and cost-effective manner without ferrite-containing special components, for instance inductively coupled coils or tapped coils thereby allowing use thereof in a magnetic resonance tomograph, for example.Type: GrantFiled: November 12, 2009Date of Patent: July 10, 2012Assignee: Siemens AktiengesellschaftInventor: Ralph Oppelt
-
Patent number: 8212563Abstract: An instrument and method using electron spin resonance spectrometry for measuring the concentration of airborne soot particles, and the like, that includes continuously passing a sample of exhaust gas through a resonating RF microwave cavity resonator during the application therethrough of a uniform slowly varying uniform magnetic field that is rapidly modulated and measuring the resulting phase modulation or amplitude modulation thereof to derive an electron spin resonance signal that directly senses the concentration of carbon free radicals produced as a result of inefficient combustion of hydrocarbons during operation of the vehicle or boiler. A further invention is the use of this signal for feedback control of the engine or boiler operating parameters to minimize or substantially eliminate particulate matter emissions.Type: GrantFiled: May 6, 2009Date of Patent: July 3, 2012Assignee: Active Spectrum, Inc.Inventors: James Robert White, Christopher John White, Colin T. Elliott, Alexander H. Slocum
-
Patent number: 8203339Abstract: An apparatus comprising a magnetic field generator for generating a magnetic field of a predetermined orientation, an element provided in the apparatus at a location that, in use, is within a region of the magnetic field having the predetermined orientation generated by the generator, and a device for determining an angle between the element and the magnetic field, the device comprising a Hall Effect sensor.Type: GrantFiled: October 19, 2007Date of Patent: June 19, 2012Assignee: University of SouthamptonInventors: Ole Gustav Johannessen, Malcolm Harris Levitt
-
Publication number: 20120133364Abstract: A method of and miniaturized apparatus adapted for in-situ measurement of degradation of automotive fluids and the like by micro-electron spin resonance (ESR) spectrometry, wherein the use of a modulated constant magnetic field in an RF resonating variable frequency microwave cavity resonator through which a fluid sample is passed, enables direct detection of molecular changes in such fluid sample resulting from fluid degradation during use.Type: ApplicationFiled: February 6, 2012Publication date: May 31, 2012Inventors: James R. White, Christopher John White
-
Publication number: 20120112746Abstract: An apparatus and method for triaging patients according to radiation exposure operates by measuring electron paramagnetic resonance spectra of fingernails, toenails, and/or teeth. A coil structure allows in vivo measurement of tooth enamel or fingernail keratin with reduced coupling to underlying tissue.Type: ApplicationFiled: August 25, 2010Publication date: May 10, 2012Inventors: James S. Hyde, Jason W. Sidabras, Richard R. Mett
-
Publication number: 20120049847Abstract: A method and system for performing pulsed electron paramagnetic resonance is disclosed. In one aspect, the method includes generating an excitation pulse train for applying to an object having probes and detecting from the probes an echo response induced by the excitation pulse train.Type: ApplicationFiled: March 29, 2011Publication date: March 1, 2012Applicant: IMECInventors: Peter Vaes, Stephanie Teughels
-
Patent number: 8125224Abstract: A method of and miniaturized apparatus adapted for in-situ measurement of degradation of automotive fluids and the like by micro-electron spin resonance (ESR) spectrometry, wherein the use of a modulated constant magnetic field in an RF resonating variable frequency microwave cavity resonator through which a fluid sample is passed, enables direct detection of molecular changes in such fluid sample resulting from fluid degradation during use.Type: GrantFiled: December 9, 2008Date of Patent: February 28, 2012Assignee: Active Spectrum, Inc.Inventors: James R. White, Christopher J. White