Abstract: Methods, systems, and devices are disclosed for molecular capture, manipulation, and analysis. In one aspect, a device to aggregate and characterize particles in a fluid includes an electrically insulative substrate including a channel to carry an electrically conducting fluid containing particles, electrodes located in the channel forming a nanoscale opening and including an insulating layer over their surface at the opening, a first circuit to apply a non-uniform ac electric field and a dc bias signal across the electrodes, in which the applied non-uniform ac electric field produces a positive dielectrophoretic force to aggregate the particles in a trapping region including the opening and adjacent region, a second circuit to detect changes in a dc current caused by at least some of the particles in the trapping region, and an optical device that directs a coherent light beam on the opening to determine Raman spectra of the particles in the trapping region.

Abstract: A method is provided to improve the usability of Design-For-Testability Synthesis (DFTS) tools and to increase the design process productivity. The method comprises receiving a list of testability and design impact analysis functions, to be performed on the circuit, also referred to as a device under test (DUT). The impact analysis leads to the creation of logical transformations, which can be selected by a user with one or more available transformation methods from a list including, but not limited to, boundary scan test logic insertion, scan test logic insertion, memory BIST (built-in-self-test) logic insertion, and logic BIST logic insertion, and scan test data compression insertion logic insertion.

Abstract: The present invention provides a method and apparatus for reducing electromagnetic noise pick up in a Liquid Metal Cleanliness Analyzer (LiMCA), used to detect and measure particles in molten metal. An first electrode inserted in the molten metal is electrically insulated from second and third electrodes, also inserted in the molten metal. Molten metal and particles pass between the first electrode and the second and third electrodes through a passage in the electrical insulation. The second and third electrodes have a configuration with respect to the first electrode sufficient to establish symmetrical current loops between the first electrode and the second and third electrodes when a current is supplied to the second and third electrodes. The current is supplied from an ultra-capacitor. Electromagnetic noise in the symmetrical current loops is detected and is added in opposition to reduce the amplitude of the electromagnetic noise.

Abstract: Improvements to the electrical sensing zone instrument are described that allow the good accuracy of this type of instrument to be applied to the measurement of the size of particles of carbon black. The improvements include a concentrated aqueous electrolyte containing KI or NaI, a surfactant soluble in the electrolyte capable of dispersing particles of carbon black, and an anode electrode that is made of silver at the surface touching the electrolyte. The silver anode electrode prevents the degradation of the electrolyte by light and electrolysis.

Abstract: The integrity of a microporous membrane within a mass transfer device such as an oxygenator is tested simultaneously with applying a biocompatible surfactant to at least the blood-contact surface of the membrane. The membrane integrity test contacts both sides of the microporous membrane with a conductive fluid to establish an electrical circuit. An electrical signal is then applied to the circuit and a measurement is taken of the test voltage across an impedance in the circuit. The value of the test voltage is used to determine the conductivity and thus the integrity of the membrane. The biocompatible surfactant is mixed with the conductive fluid used in the electrical integrity test and has an affinity for the microporous membrane material so that a durable biocompatible coating is applied to at least a portion of the microporous membrane.

Abstract: A novel method for detecting charge on large bodies such as the earth is accomplished by means of disclosed apparatus which includes a vertical column of mercury having an associated electrode which is capacitively coupled to the mercury column when the mercury level is above the position of the electrode. By establishing an initial unipotential state for the apparatus by short circuit connection of the electrode and mercury column to the earth and an electrometer connected between the electrode and the earth which is initially short-circuited across its terminals the apparatus is conditioned to sense the charge of the large body to which it is connected (the earth) by moving the mercury column up and down past the position of the electrode with the electrometer open-circuited and thus connected between the electrode and earth during the passage of the mercury in one direction past the electrode.