Abstract: Systems and methods are provided for monitoring eye movements of a user, and diagnosing and treating eye conditions substantially in real-time. A visual display device is provided with optical display fields corresponding to eyes of the user, and a controller linked to the device is programmed to measure eye positions with respect to the display device and determine optical deviations in any eye with respect to a central visual axis of the other (dominant) eye. In response to deviations exceeding a first value, an occlusion spot is generated in the display field for the dominant eye of a size corresponding to the degree of optical deviation. The location of the occlusion is continuously adjusted in accordance with real-time movements of the dominant eye based on the received signals from the device. When the optical deviation falls below a second value, occlusion of the dominant eye is disabled.

Abstract: Disclosed are various embodiments for automatic scrolling of content displayed on a display device in response to gaze detection. Content may be displayed in a window rendered on a display screen. Gaze detection components may be used to detect that a user is gazing at the displayed content and to determine a gaze point relative to the display screen. At least one applicable scroll zone relative to the display screen and a scroll action associated with each applicable scroll zone may be determined. In response to determining that the gaze point is within a first applicable scroll zone, an associated first scroll action may be initiated. The first scroll action causes the content to scroll within the window until at least one of: expiration of a defined period, determining that a portion of the content scrolls past a defined position within the window, determining that the gaze point is outside of the first scroll zone, and detecting an indicator that the user begins reading the content.

Abstract: A reading meter system and method is provided for identifying the existence and position of text in visual media content (e.g., a document to be displayed (or being displayed) on a computer monitor or other display device) and determining if a subject has interacted with the text and/or the level of the subject's interaction with the text (e.g., whether the subject looked at the text, whether the subject read the text, whether the subject comprehended the text, whether the subject perceived and made sense of the text, and/or other levels of the subject's interaction with the text). The determination may, for example, be based on data generated from an eye tracking device. The reading meter system may be used alone and/or in connection with an emotional response tool (e.g., a software-based tool for determining the subject's emotional response to the text and/or other elements of the visual media content on which the text appears).

Abstract: Minor traumatic brain injury is detected by operating (a) an image generator for presenting a visual stimulus having a predetermined movement across a visual field of a subject and (b) a sensor device for monitoring fast eye movement of the subject while the subject views the stimulus. The sensor device generates a signal encoding the subject's eye position. A computer or microprocessor operatively connected to the sensor device is configured for determining a parametric value for the fast eye velocity component.

Abstract: An eye tracking method for determining a position of an eye or a part of an eye in an image of an image sequence by performing a comparison between said image and a reference image, said process including: aligning a set of images; computing an enhanced reference image based on a combination of said set of aligned images; and determining said position in said image of said image sequence by comparing said image of said image sequence and said enhanced reference image to yield a motion estimation between said reference image and said image of said sequence.

Abstract: A system and method for assessing the function of parts of the nervous system of a subject by measuring the pupillary responses to at least one stimulus ensemble comprising a plurality of individual stimuli; the method comprising: presenting a sequence of selected individual stimuli from the at least one stimulus ensemble to the nervous system of a subject thereby evoking pupillary responses in at least one pupil of the subject, selected individual stimuli being concurrently presented in the sequence, wherein the individual stimuli are each individually balanced such that the pupillary responses evoked by individual stimuli in the ensemble are balanced according to the strength of the neural responses evoked by the individual stimuli; detecting responses of the pupil or pupils evoked by the stimuli using a sensor; and processing the detected responses to relate them to the function of the subject's neural responses to some or all of the individual stimuli of the ensemble.

Abstract: Provided is an image acquisition apparatus for acquiring a 3D retinal image with high resolution, which is capable of reducing a time period required for data transmission. In the image acquisition apparatus: a blink of a subject is detected; acquisition of image taking data is suspended thereafter until a line of sight becomes stable; and the data transmission to a computer is started at a timing at which a blink has been detected, thereby avoiding acquiring unnecessary data, allowing a capacity of a data buffer to be smaller, and making the data transmission efficient.

Abstract: A fundus photographing apparatus includes a wavefront detecting optical system having a wavefront sensor for receiving reflection light from a fundus and measuring wavefront aberration of an eye, a wavefront compensating device for compensating the wavefront aberration, and a deviation detecting part for detecting deviation information corresponding to deviation between an effective region in which aberration compensation by the wavefront compensating device is effective, and a wavefront measuring region in which the wavefront aberration is measured by the wavefront detecting optical system, with respect to a direction perpendicular to an optical axial direction.

Abstract: Methods and compositions are disclosed to quantitatively measure in vivo blood vessel diameter, blood velocity, and other flow dynamics. Such methods and compositions can optimize therapeutic interventions designed to prevent or reduce the risk of cardiovascular and blood disorders. In one aspect, the methods and apparatus involve calculating blood vessel characteristics from a two dimensional image of a blood vessel in the conjunctiva of a subject's eye. In another aspect, a series of temporal images of a blood vessel are obtained to determine blood flow properties. The apparatus can include, for example, a biomicroscope, an illuminating light source and a high speed camera to acquire the series of temporal images with the data then analyzed by a programmed processor.

Abstract: To provide a human state estimating device which accurately estimates a human state. The human state estimating device includes: a storage unit (16) which stores reference data (17) in which a human state and a reference profile including a horizontal component of a standard microsaccade in the human state are corresponded to each other, for each of plural personal attribute information; a video obtaining unit (11) which obtains video of a user's eyeball, with an eyeball rotation angle accuracy of 0.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: The present systems and methods provide a mechanism to assess viewer behavior, features of stimuli, and the interaction between viewer behavior and stimuli. The systems and methods described herein for quantifying blink response and blink inhibition provide moment-by-moments measurements of viewer engagement by measuring what is or is not engaging enough to warrant viewers' inhibition of blinking. The present disclosure describes measures of visual scanning, eye movements, blink data, and blink timing data to derive a measure of how engaged a person is with what he or she is looking at. Blink-related data as a measure of viewer engagement provides a mechanism for determining the most engaging spatial and temporal aspects of a stimulus.

Abstract: Provided is a display apparatus that may estimate a degree of visual fatigue corresponding to an input 3-dimensional (3D) image, using a visual fatigue model to estimate the degree of visual fatigue of a user. The display apparatus may reduce the degree of visual fatigue of the user by rescaling a depth level of the input 3D image based on the degree of visual fatigue.

Abstract: A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.

Abstract: Detecting position information related to a face, and more particularly to an eyeball in a face, using a detection and ranging system, such as a Radio Detection And Ranging (“RADAR”) system, or a Light Detection And Ranging (“LIDAR”) system. The position information may include a location of the eyeball, translational motion information related to the eyeball (e.g., displacement, velocity, acceleration, jerk, etc.), rotational motion information related to the eyeball (e.g., rotational displacement, rotational velocity, rotational acceleration, etc.) as the eyeball rotates within its socket.

Abstract: The technology provides various embodiments for controlling brightness of a see-through, near-eye mixed display device based on light intensity of what the user is gazing at. The opacity of the display can be altered, such that external light is reduced if the wearer is looking at a bright object. The wearer's pupil size may be determined and used to adjust the brightness used to display images, as well as the opacity of the display. A suitable balance between opacity and brightness used to display images may be determined that allows real and virtual objects to be seen clearly, while not causing damage or discomfort to the wearer's eyes.

Abstract: Methods and systems for determining a physiological parameter of a subject through interrogation of an eye of the subject with an optical signal are described. Interrogation is performed unobtrusively. The physiological parameter is determined from a signal sensed from the eye of a subject when the eye of the subject is properly aligned with regard to an interrogation signal source and/or response signal sensor.

Abstract: Methods and system for determining a physiological parameter of a subject through interrogation of an eye of the subject with an optical signal are described. Interrogation is performed unobtrusively. The gaze direction of the eye of the subject is determined and an interrogation signal source and/or response signal sensor are moved into alignment with the eye using an actuator to facilitate detection of the signal from the eye of the subject.

Abstract: A system, method and program product for providing a reflexive data collection system and a reflexive data verification system. A system is provided that includes: a system for defining a set of environmental conditions; a device for automatically implementing the set of environmental conditions; a system for collecting biometric data under the set of environmental conditions; and a system for encoding the biometric data and the set of environmental conditions into a reflexive template.

Abstract: A system, method and program product for providing a reflexive data collection system. A system is provided that includes: a system for defining a set of environmental conditions; a device for automatically implementing the set of environmental conditions; a system for collecting biometric data under the set of environmental conditions; and a system for encoding the biometric data and the set of environmental conditions into a reflexive template.

Abstract: An instrument is proposed for examining or machining a human eye, with an eye-tracker for acquiring eye movements and for outputting a signal that is representative of the acquired eye movements, the eye-tracker including an interferometric image-acquisition device that has been set up for time-resolved acquisition of sectional images of the eye and that operates on the basis of two-dimensional or three-dimensional optical coherence tomography, and also an evaluating module ascertaining the eye movements solely from the sectional images.

Abstract: A method and apparatus are provided for the differential diagnosis of a patient with progressive supranuclear palsy (PSP) from a patient with Parkinson's disease (PD). One method includes identifying a plurality of partially repetitive eye movements that over time define square wave jerks, each square wave jerk of the plurality of square wave jerks defined by a first horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of square wave jerks, comparing the vertical component with a threshold value. PSP or PD is identified by comparison of the vertical component with the threshold value. In another embodiment, a patient's saccade rate is determined and compared to a threshold value, and PSP or PD is identified based upon the comparison of the saccade rate with the threshold value.

Abstract: A binocular pupillometer apparatus is provided with processing means to calculate the relative afferent pupillary defect (RAPD) in a subject. The RAPD is calculated as the shift required to bring the two pupillary responses of the left and right eyes into coincidence. Where the responses are not parallel, modified pupillary responses are determined having the same area difference between the responses and an average rate of change with respect to stimulation intensity. The RAPD is calculated from the modified pupillary responses rather than the observed responses. Improvements to the pupillometer include a divider positioned between the left and right stimulating channels.

Abstract: This document provides methods and materials for quantifying ocular counter roll and detecting vestibular otolith damage. For example, devices for quantifying ocular counter roll, methods of making devices for quantifying ocular counter roll, and methods for using a device to quantify (e.g., quantify indirectly) ocular counter roll are provided.

Abstract: An imaging apparatus for obtaining a tomographic image of an object based on light obtained by combining returning light from the object, which is irradiated with measurement light, and reference light corresponding to that measurement light, the imaging apparatus comprising: a reference light splitting unit adapted to split the reference light into a plurality of reference light beams of different wavelength ranges, and a plurality of dispersion compensation units adapted to compensate dispersion in accordance with wavelength ranges of the plurality of reference light beams, the dispersion compensation units being provided in respective light paths of the plurality of reference light beams.

Abstract: The eye movement, body movement, and/or physiological performance of a subject may tracked while the subject performs a task, such as participating in an activity or sport. The collected data may then be used to identify correlations between the subject's eyesight and the subject's body movement exists and/or physiology. Such a correlation may be analyzed (e.g., over time) to determine any delays or gaps in the subject's ability to track an object, such as a ball, while participating in a sport or other activity. Further, a subject's performance may be compared to data collected from other individuals. The eye movement, body movement, and/or physiological performance data may be used to test and/or train the visual and cognitive abilities of an individual.

Abstract: Systems and methods are provided for monitoring eye movements of a user, and diagnosing and treating eye conditions substantially in real-time. A visual display device is provided with optical display fields corresponding to eyes of the user, and a controller linked to the device is programmed to measure eye positions with respect to the display device and determine optical deviations in any eye with respect to a central visual axis of the other (dominant) eye. In response to deviations exceeding a first value, an occlusion spot is generated in the display field for the dominant eye of a size corresponding to the degree of optical deviation. The location of the occlusion is continuously adjusted in accordance with real-time movements of the dominant eye based on the received signals from the device. When the optical deviation falls below a second value, occlusion of the dominant eye is disabled.

Abstract: A gaze target determination device includes an event setting unit that generates, for each object at different times, a display event which triggers a movement of the gaze direction of the user who is gazing at the object and which indicates a movement or a change of the object; and a gaze trajectory calculation unit that calculates a gaze trajectory based on the detected user's gaze direction. An eye movement event detection unit detects an event detection time which is a time at which the gaze direction moves according to the display event, based on the calculated gaze trajectory. A synchronization structure analysis unit calculates, for each object, time difference between the event detection time and event occurrence time; and a gaze target determination unit determines the object at which the user is gazing from among the objects, based on the calculated time difference.

Abstract: Optical coherence tomographic imaging apparatus creating tomographic image of inspection object includes light splitting means for splitting light from light source into a single reference light and a single sample light, optical path length changing means for changing optical path length of the single reference light, reference light splitting means for splitting the single reference light whose optical path length is changed into a plurality of reference lights, sample light splitting means for splitting the single sample light into a plurality of sample lights, irradiation means for irradiating the inspection object by leading the plurality of sample lights thereto, interference signal forming means for combining returning lights of the plurality of the sample lights from the inspection object irradiated by the irradiation means with the plurality of reference lights passed through the reference-light path, and interference signal obtaining means for obtaining an interference signal from the interference s

Abstract: This invention relates to methods and apparatus for improving communications between humans and devices. The invention provides a method of modulating operation of a device, comprising: providing an attentive user interface for obtaining information about an attentive state of a user; and modulating operation of a device on the basis of the obtained information, wherein the operation that is modulated is initiated by the device. Preferably, the information about the user's attentive state is eye contact of the user with the device that is sensed by the attentive user interface.

Abstract: The OculoKinetic Device is used to test an individual to evaluate brain functions and to identify the presence of a traumatic brain injury or disease which manifests itself through abnormal ocular responses to stimuli by using the high-speed tracking of an individual's eye movements, pupil size and reactivity, eye lid position and blink parameters and optionally along with other ocular elements, i.e., eyeball pressure, temperature, blood flow, etc. The eye movement stimulus protocol uses a target that moves in any direction of the two-dimensional plane and may use a color display or geometric shapes. In addition, the stimuli can be used in conjunction with cognitive testing, balance assessment, and other non-eye tests.

Abstract: A binocular viewer, a method of measuring and training vision that uses a binocular viewer and a vision measurement and training system that employs a computer to control the binocular viewer. In one embodiment, the binocular viewer has left and right display elements and comprises: (1) a variable focal depth optical subsystem located in an optical path between the display elements and a user when the user uses the binocular viewer and (2) a control input coupled to the left and right display elements and the variable focal depth optical subsystem and configured to receive control signals operable to place images on the left and right display elements and vary a focal depth of the variable focal depth optical subsystem. In another embodiment, the binocular viewer lacks the variable focal depth optical subsystem, but the images include at least one feature unique to one of the left and right display elements.

Abstract: A method determines the position and/or radius of the limbus and/or the position and/or radius of the pupil of a patient eye. In the method, an image of the patient eye is obtained and a plurality of different ring-shaped comparison objects having respective radii and respective centers are provided. The image is correlated with the plurality of comparison objects to yield a local best match between the image and the comparison objects when there is a coincidence of one of the ring-shaped comparison objects and a ring-shaped jump in brightness in the image having the same radius and the same center. The comparison objects having a local best match with the image are determined. Thereafter, the position of the center of the comparison object having a local best match with the image is selected as the position of the center of the limbus and/or the position of the center of the pupil.

Abstract: An embodiment of the invention provides a focus adjustable apparatus adapted to be disposed on a transparent substrate to modulate a plurality of rays passing through the transparent substrate. The focus adjustable apparatus includes a light modulation device, an eye tracking device, an eyesight status device and a controller. The light modulation device receives the rays from the transparent substrate and adjusts an emergent angle of each ray. The eye tracking device tracks a position of a user and estimates a distance between the user and the focus adjustable apparatus. The eyesight status device obtains an eyesight data of the user. The controller provides a control signal to drive the light modulation device by estimating the emergent angle of the each ray according to the distance between the user and the focus adjustable apparatus and the eyesight data of the user.

Abstract: The invention relates to ophthalmic spectacles for characterizing the direction of gaze of a wearer. Each lens of the spectacles is provided with output sections for directing a radiation towards the ocular areas of the wearer, in which different portions of an ocular limbus of the wearer are in motion. The lens is further provided with input sections for collecting the portions of said radiation reflected in said ocular areas. A computing unit is also combined with the spectacles in order to determine the direction of gaze of the wearer from detection signals measuring the portions of the radiation that are simultaneously collected by the input sections of the two lenses.

Abstract: A portable non-contact tonometer (2) for measuring Intra-Ocular Pressure (IOP) of subject's eye is presented. Tonometer (2) is designed to be operated by the subject himself. It is housed in a hand-held case (4) which contains compressed air source (40), eye alignment detectors (12, 14), cornea applanation detector system (8, 10), a pressure sensor (32) and optical system for presenting gaze target (48). The animated gaze target (48) advantageously draws subject's attention to itself and keeps his eye (62) in alignment long enough for the measurement to take place, while optionally displaying system status and operating instructions. An audio annunciation system (16) guides the subject in the operation of the tonometer and prepares him for the actual procedure. The timing of the air puff is randomized to prevent subject's conditioning. The overall operation of the tonometer is controlled by a built-in microprocessor (50) system.

Abstract: A learning-based visual attention prediction method is disclosed. The method includes a correlation relationship between the fixation density and at least one feature information being learned by training, followed by a test video sequence of test frames being received. Afterward, at least one tested feature map is generated for each test frame based on the feature information. Finally, the tested feature map is mapped into a saliency map, which indicates the fixation strength of the corresponding test frame, according to the correlation relationship.

Abstract: An SS OCT interferometry device for measuring a sample, in particular from an eye. The device interferometrically generates a measuring signal and from the signal a depth-resolved contrast signal of the sample by spectral tuning of the central wavelength of the measurement radiation of a measuring signal, and has a control unit for this purpose. The device includes a sample motion detector, which provides a motion signal indicating movement of or in the sample, the control unit uses the motion signal to correct the measuring signal with respect to measuring errors that are caused by a movement of or in the sample before or during the generation of the depth-resolved contrast signal.

Abstract: System for monitoring at least one biomechanical ophthalmic parameter, the system comprising a measuring device (1) adapted to be placed on or implanted into an eye of a patient for measuring said at least one biomechanical ophthalmic parameter of said eye, a recording device (6) for obtaining from said measuring device (1) measurement data representative of the instant value of said at least one biomechanical ophthalmic parameter of said eye, wherein said recording device is adapted to obtain said measurement data at a predetermined frequency equal to or greater than twice the variation frequency of said at least one biomechanical ophthalmic parameter.

Abstract: Various embodiments of a device for performing a gaze field sobriety test are disclosed. The device includes a housing. A light source is affixed in or on the housing. The light source generates light during at least a portion of the gaze field sobriety test. A speaker positioned in or on the housing generates sounds during at least a portion of the gaze field sobriety test. A power source is coupled to the speaker and the light source. An input is positioned on the housing. The input is selectable by a test administrator to initiate an audible sound through the speaker at a predetermined time interval during at least a portion of the gaze field sobriety test. The audible sound provides an indication to the test administrator during the gaze field sobriety test to assist in proper performance of the gaze field sobriety test.

Abstract: Disclosed herein is a method of calculating tear film lipid and aqueous layer thicknesses and/or corneal surface refractive index from interferometry data obtained from simultaneous measurements of the aqueous and lipid layers of the tear film along with a measurement of the corneal surface reflectance.

Abstract: A method to track a user's gaze for medical diagnostics is described. The method includes detecting a gaze behavior of a user in response to a stimulus. The stimulus is a non-diagnostic stimulus. The method also includes determining a type of the stimulus and generating an indication of the gaze behavior and the type of the stimulus. The indication may then be used to generate an expected gaze pattern describing expected gaze behavior to given stimuli. Additionally, the indication may be used to determine whether the gaze behavior is indicative of a potential problem and, in response, an alert may be generated. Apparatus and computer readable media are also described.

Abstract: In addition to a first detector for capturing a potential movement field of the eye in overview images, a second detector is used to capture a particular section of the eye in sectional images. From a displacement between two overview images and an intermediate displacement between two sectional images taken between said overview images, the eye movement is determined by linking said displacements. The sections are preferably illuminated by coherent light such that interfering light diffused on the eye produces a patch pattern. Alternatively, the sclera of the eye is illuminated with coherent light such that light diffused on the sclera produces a patch pattern, of which a particular part is captured using a spatially resolving detector in sectional images, on the basis of which an intermediate displacement is determined.

Abstract: A device (1) for determining the visual field comprises a screen (11) for displaying test patterns, an eye monitoring module (13) for capturing eye movements of a patient (20), and a processing module (10) for determining the visual field of the patient on the basis of the eye movements when the test patterns are displayed. The device (1) moreover comprises a mirror (12), which is aligned parallel to the bipupillary line of the patient (20) for determining the visual field, for deflecting the test patterns from the screen (11) to the eyes. The use of the mirror (12) aligned parallel to the bipupillary line of the patient results in a particularly compact design of the device (1) for determining the visual field, which device makes the same geometric and optical measurement conditions possible for both eyes.

Abstract: Embodiments of the invention refer to a system for registering and tracking the position of a person's eye, in particular for refractive ophthalmic surgery. According to embodiments, the system is structured such that eye images containing at least the iris and the pupil of the eye are made at a first wavelength of light and that eye images containing scleral blood vessels are made at a different second wavelength of light. The invention furthermore refers to a corresponding method for registering and tracking the position of a person's eye.

Abstract: A universal headset-mounted Neuropsychological Testing System utilizes eye tracking, with a single screen fixed with respect to the face and a dot on the screen driven to present an object that both eyes are focused on using a set of prisms, with the prisms eliminating interocular distance considerations. Ultrathin optics cast a virtual image at 40 centimeters and a universal mask against which the test taker's face is placed fixes the single screen with respect to the face so that head movement is not a factor. Additionally, miniature cameras are located in the headset housing beneath the eyes, and a quick release tensioning unit provides easy headset mounting and removal. Moreover, all elements are located in the headset hood to eliminate the effects of head movement as well as environmental distractions.

Abstract: Minor traumatic brain injury is detected by operating (a) an image generator for presenting a visual stimulus having a predetermined movement across a visual field of a subject and (b) a sensor device for monitoring fast eye movement of the subject while the subject views the stimulus. The sensor device generates a signal encoding the subject's eye position. A computer or microprocessor operatively connected to the sensor device is configured for determining a magnitude for the fast eye velocity component.

Abstract: Detecting position information related to a face, and more particularly to an eyeball in a face, using a detection and ranging system, such as a Radio Detection And Ranging (“RADAR”) system, or a Light Detection And Ranging (“LIDAR”) system. The position information may include a location of the eyeball, translational motion information related to the eyeball (e.g., displacement, velocity, acceleration, jerk, etc.), rotational motion information related to the eyeball (e.g., rotational displacement, rotational velocity, rotational acceleration, etc.) as the eyeball rotates within its socket.

Abstract: Systems and methods are disclosed for evaluating human eye tracking. One method includes receiving data representing the location of and/or information tracked by an individual's eye or eyes before, during, or after the individual performs a task; identifying a temporal phase or a biomechanical phase of the task performed by the individual; identifying a visual cue in the identified temporal phase or biomechanical phase; and scoring the tracking of the individual's eye or eyes by comparing the data to the visual cue.

Abstract: An ophthalmic device and method actively correcting possible movement of the eye of a patient with respect to the correct positioning during the examination are described. An illumination light beam is provided, that passes through a cross-section of the anterior chamber of the eye to capture an image on the corneal vertex.