Abstract: A processor or control circuit of an apparatus receives data of an image based on sensing by one or more image sensors. The processor or control circuit also detects a region of interest (ROI) in the image. The processor or control circuit then adaptively controls a light projector with respect to projecting light toward the ROI.

Abstract: A device and a method for the femtosecond laser surgery of tissue, especially in the vitreous humor of the eye. The device includes an ultrashort pulse laser with pulse widths in the range of approximately 10 fs-1 ps, especially approximately 300 fs, pulse energies in the range of approximately 5 nJ-5 ?J, especially approximately 1-2 ?J and pulse repetition rates of approximately 10 kHz-10 MHz, especially 500 kHz. The laser system is coupled to a scanner system which allows the spatial variation of the focus in three dimensions (x, y and z). In addition to the therapeutic laser/scanner optical system, the device includes a navigation system.

Abstract: A feature value related to a positional relationship between a vortex vein position and a characteristic point on a fundus image is computed. The image processing method provided includes a step of analyzing a choroidal vascular image and estimating a vortex vein position, and a step of computing a feature value indicating a positional relationship between the vortex vein position and a position of a particular site on a fundus.

Abstract: An optical coherence tomography apparatus includes a control unit configured, before a tomographic image to be stored is obtained using the output from the light receiving unit during a period in which the measurement light is scanned in a first scanning pattern for scanning an image capturing region of the subject eye, to control the optical scanning unit so as to repeatedly scan the measurement light in a second scanning pattern for scanning the measurement light over at least part of the image capturing region in a scanning time shorter than a scanning time of the first scanning pattern and to control the driving unit so as to drive the focusing unit using the output from the light receiving unit during a period in which the measurement light is repeatedly scanned in the second scanning pattern.

Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.

Abstract: An optical coherence tomography (OCT) scan device includes an OCT scan device housing, an interferometer disposed in within the OCT scan device housing and including a light source, a fiber optic coupler including an interferometer output, a reference-arm, and a sample-arm. The OCT scan device further includes a power source configured to provide power to the light source and the remaining components of the OCT scan device, and a controller disposed within the OCT scan device housing and configured to adjust lens focusing parameters in the reference-arm and the sample-arm, and control a scanning function of an optical beam emitting from the sample-arm. The OCT scan device is further configured to transmit and receive control instructions and transmit fundus image data.

Abstract: Disclosed herein are methods for simulating the results of a visual field (VF) test using an optical coherence tomography (OCT) system. The disclosed methods may utilize structural information extracted from OCT image datasets, such as thickness measurements, or may utilize functional information, such as blood perfusion measurements, extracted from OCT angiography (OCTA) image datasets. Other embodiments may be described and claimed.

Abstract: An ophthalmic scanning system includes a first imaging modality, a second imaging modality different from the first imaging modality, and a control system that maps the first imaging modality to the second imaging modality by compensating for at least one of an optical-mechanical and an electro-mechanical projection difference between the first and second imaging modalities. The control system provides a scan location for the second imaging modality based on a scan location of the first imaging modality.

Abstract: A system tracks eye movement using optical coherence in a head mounted display. The system includes an illumination source configured to project low coherence interference light onto a portion of a user's eye. The system includes a scanning system to select an axial position within the illuminated portion of the user's eye. The system includes a detector configured to collect light reflected from the illuminated portion of the user's eye at the selected axial position, and the reflected light includes measurement data characterizing the illuminated portion of the user's eye. The system includes a controller configured to compare the measurement data with a trained baseline, and determine an eye position based the comparison.

Abstract: Eye fundus inspection apparatus (500) comprising: —illumination means (12) comprising at least a light source (121, 123, 124, 126) and adapted to project a first light beam (1) towards a retina (101) of an eye (100); —an optical lighting path (1A) for said first light beam; —acquisition means (27) adapted to receive a second light beam (2) coming from the retina; —an optical acquisition path (2A) for said second light beam; —scanning means (17) adapted to scan said first light beam (1) on the retina with a linear movement, according to a first scanning direction (S1), or with a circular movement about a rotation axis (A), according to a second scanning direction (S2); —light beam separating means (16) adapted to define separate passage zones for said first and second light beams (1, 2) at a pupil of the eye; —a control unit (120) adapted to control operation of said inspection apparatus; —first light beam shaping means (11) and second light beam shaping means (23, 271, 272) that allow obtaining improved retin

Abstract: The present invention relates to aids or devices with optical elements which include a partially reflective surface, which allow examination or recordal of a patient who is fixated on a visual target, with said examination or recordal occurring along the same axis as the line of sight. The invention also allows for a target more personalised and customised to the patient's needs.

Abstract: A spectroreflectometric system for performing a spectral analysis on the fundus of a patient's eye or other medium is provided. The system includes an imaging device and a spectral analyser. Illumination light from an illumination light source is projected towards the fundus of the patient's eye. The resulting light from the fundus is separated by a beam splitter into an imaging portion travelling along an imaging light path to reach the imaging device and a spectral analysis portion deviated to a spectral analysis light path. The system further includes a pointer light source optically coupled to the spectral analysis light path. The system is operable in an acquisition mode to concurrently obtain an image of the fundus of the patient's eye and a spectral analysis of an analysis spot on this fundus, and in a pointer mode to obtain a visual representation of the analysis spot within the image.

Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.

Abstract: Apparatus for evoking and sensing ophthalmic physiological signals in an eye, the apparatus comprising: an elongated light pipe having a longitudinal axis, a distal end and a proximal end, the distal end terminating in a spheroidal recess; and an electrode having a distal end and a proximal end, the electrode being mounted to the elongated light pipe and extending proximally along the elongated light pipe so that the distal end of the electrode terminates at the spheroidal recess at the distal end of the elongated light pipe.

Abstract: An optical system for a laser therapy instrument for the application of laser radiation on and in the eye, includes a femtosecond laser, an objective. The objective or at least one lens or lens group of the objective is shiftable in the direction of the optical axis being intended for shifting of the focus position from the region of the cornea to the region of the crystalline lens and vice versa. The optical system may include at least two optical assemblies designed for the axial variation of the focus of the therapeutic laser radiation, with the focus variation range ?z differing between the individual assemblies and a changing device, designed for the insertion of any one of these assemblies into the therapeutic laser beam path at a time.

Abstract: An eye measurement system includes an optical system. The eye measurement system is disposed in a housing which includes an aperture for providing light to and from the optical system and a subject's eye while the subject is separated and spaced apart from the housing, and the eye is not maintained in a fixed positional relationship with respect to the housing. An optical system movement arrangement moves the optical system. An automatic eye tracking arrangement ascertains a current positional relationship of the eye with respect to the optical system without human assistance, and in response thereto controls the optical system movement arrangement to move the optical system into a predetermined positional relationship with respect to the eye, for measurement of the eye, without human assistance. The eye measurement system can make objective, and/or subjective, refraction measurements of the eye.

Abstract: An ophthalmic apparatus may include a first light source configured to output a first light, a second light source configured to output a second light, a first interferometer configured to execute an examination of a first range using first interference light, and a second interferometer configured to execute an examination of a second range using second interference light, the second range being different from the first range. A central wavelength of the first light may be different from a central wavelength of the second light. A first optical path and a second optical path may at least partially overlap with each other, the first optical path being an optical path of the first light, and the second optical path being an optical path of the second light. The examination of the first range and the examination of the second range may be able to be executed simultaneously.

Abstract: In accordance with one aspect of the present invention, an optical coherence tomography instrument comprises an eyepiece for receiving at least one eye of a user is provided; a light source that outputs light that is directed through the eyepiece into the user's eye; an interferometer configured to produce optical interference using light reflected from the user's eye; an optical detector disposed so as to detect said optical interference; and electronics coupled to the detector. The electronics can be configured to perform a risk assessment analysis based on optical coherence tomography measurements obtained using the interferometer. An output device can be electrically coupled to the electronics, and may be configured to output the risk assessment to the user through the output device. The optical coherence tomography instrument can be self-administered, and the eyepiece can be a monocular system or a binocular system.

Abstract: The invention provides a chromatic confocal system for inspecting an object. The system comprises a first light modulator for providing a spatially modulated light beam arranged to project on one or more parts of the object to form a reflected light beam carrying image information of the one or more projected parts of the object; a second light modulator for spatially filtering the reflected light beam to form a light beam carrying filtered image information of the one or more projected parts of the object; wherein operation of the first light modulator and the second light modulator is synchronized such that the spatial filtering of the second light modulator varies in concert with variations in the spatial modulation of the first light modulator.

Abstract: In one aspect, the disclosure provides a method of defining a Raman signature of a culture component, the method comprising: obtaining a Raman spectrum of a culture component in a non-interfering or minimally-interfering solution, identifying peaks in the Raman spectrum that are associated with the culture component, obtaining a Raman spectrum of a culture medium comprising the culture component, and, removing peaks of the culture component in the Raman spectrum of the culture medium that are distorted compared to the peaks identified in the Raman spectrum of the culture component in a non-interfering or minimally-interfering solution.

Abstract: A system for processing a portion in a processing volume of a transparent material by application of focused radiation including a device for generating and an optical system for focusing radiation, with a device for changing the position of the focus of the radiation and a control device. This system performs a slow scanning movement of the focus and an independent fast scanning movement of the focus which section can be moved by the slow scanning movement in the entire processing volume in an arbitrary direction; as well as by a system into which a scan pattern is encoded, with scanning movement including at least one lateral base component in the x- and/or y-direction, which is superimposed by components with synchronous change-of-direction-movements in the z-direction and in x-direction and/or y-direction. The invention also includes corresponding methods, a control program product and a planning unit.

Abstract: A mobile communication device-based corneal topography system includes an illumination system, an imaging system, a topography processor, an image sensor, and a mobile communication device. The illumination system is configured to generate an illumination pattern reflected off a cornea of a subject. The imaging system is coupled to an image sensor to capture an image of the reflected illumination pattern. A topography processor is coupled to the image sensor to process the image of the reflected illumination pattern. The mobile communications device includes a display, the mobile communications device is operatively coupled to the image sensor. The mobile communications device includes a mobile communications device (MCD) processor. A housing at least partially encloses one or more of the illumination system, the imaging system, or the topography processor.

Abstract: An ophthalmological apparatus includes a handle for manually holding and applying the ophthalmological apparatus, fastening abilities for fixing the ophthalmological apparatus at an eye, a light source, and a light projector for the focused projection of light pulses for punctiform tissue breakdown at a focal point in the interior of the eye tissue. The ophthalmological apparatus also includes a movement driver for moving the light projector. The movement of the light projector and therefore that of the focal point with the assistance of the movement driver permits a dimensioning of the optical projection system of the light projector which is substantially smaller than in the case of an ophthalmological apparatus where the focal point is moved exclusively by an optical projection system.

Abstract: Ocular devices worn on the eye and through-body communication networks for communicating with an ocular device and other devices interconnected to the through-body communication network are disclosed. Devices and networks for using the body to communication between an ocular device and an on-body and off-body communication networks are disclosed. An ocular device includes electrodes configured to be electrically coupled to the body through tear fluid of the eye when worn on the eye of a user. Electrodes interconnected to the body establish communication with on-body network devices and off-body network devices.

Abstract: An ophthalmologic apparatus includes: an ophthalmologic apparatus body having: an objective lens that faces a subject's eye; a first illumination optical system that irradiates a cornea of the subject's eye with illumination light emitted from a first illumination light source along an optical axis overlapping an optical axis center of the objective lens; an interference image capturing camera that takes an image of a corneal reflection light through the objective lens and outputs an imaging signal; and a calculation unit that calculates, based on a corneal reflection image, of a corneal reflection light, input from the interference image capturing camera, a thickness of a tear fluid film at each position on the corneal surface; and a guide rail that supports the ophthalmologic apparatus body.

Abstract: A device and method of ophthalmic diagnosis of lesions on retina utilizing a slit lamp apparatus with a pupil reader and at least one visible LED and one Infrared LED to detect a lesion on the retina of an eye.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: Methods and apparatus are described for illuminating the fundus of an eye for wide-angle fundus photography. The present disclosure delivers light through a pars planar area of the eye for illuminating the interior of the eye, or through an eyelid and a pars plana of the eye. Trans-pars-planar illumination frees the entire pupil for imaging and therefore eliminates need for pupil dilation or complex balancing between illumination and imaging in previous wide-angle fundus photography based on trans-pupillary illumination. Additionally, the present disclosure discloses, when an optical fiber bundle multiple-channel trans-pars-planar illuminator placed adjacent to the pars plana, at least one optical fiber in the optical fiber bundle aligns with the pars plana to deliver light through the pars plana into the fundus of the eye, thus eliminating the previous problem of having to move an optical fiber to search a location of the pars plana.

Abstract: An ophthalmic surgical microscope includes a main objective lens, through which an observation beam path passes, and a confocal optical system configured as a refractometer to determine the refraction of an eye. The optical system includes a measurement light source to generate a measurement light beam, a light detector to measure an intensity of measurement light and an optical unit to direct the measurement light beam onto the retina of the eye and to return measurement light reflected back at the retina to the light detector. The optical system includes an adaptive optical module (AOM) to modify a wavefront of the measurement beam path such that an intensity of the back-reflected measurement light changes. A spherical equivalent (SE) of the ametropia of the eye is determined based on a setting of the AOM, at which the measured intensity of the back-reflected measurement light has a maximum.

Abstract: An apparatus and method of controlling an eye assembly of a patient simulator. The method generally includes receiving, via a data input device, one or more inputs, transmitting the one or more inputs to a controller in communication with the data input device, and controlling, using the controller and based on the one or more inputs, the eye assembly of the patient simulator to simulate ocular disease, which ocular disease includes nystagmus, blepharospasm, ptosis, idling, or a combination of two or more thereof.

Abstract: An apparatus, and corresponding method, for determining a refractive property of an eye includes a housing with a port configured to receive an eye and also light from the eye. A tunable lens can be mounted to the housing to apply a variable focal power to the light from the eye and to pass the light along an optical path toward a wavefront sensor within the housing. The wavefront sensor can receive the light via the optical path and measure a wavefront thereof. A determination module can be configured to determine a property of the eye based on the wavefront. Embodiments can be handheld, portable, and open view, while providing objective wavefront aberrometry, subjective phoroptry, and accommodation and presbyoptic evaluation, as well as lensometry functions.

Abstract: A display device includes a first diffraction element that diffracts light emitted from a light source section in front of an observer such that the light is directed to an eye of the observer, and a second diffraction element that is disposed in an optical path from the light source to the first diffraction element to diffract the light such that the light is directed to the first diffraction element. The first diffraction element has a wider wavelength width than the second diffraction element at the half value of diffraction efficiency with respect to light in a first wavelength range, a second wavelength range, and a third wavelength range. This structure reduces a decrease in intensity of the light diffracted by the second diffraction element and the first diffraction element even if a wavelength at which diffraction efficiency is maximum is shifted in the first diffraction element.

Abstract: An OCT system for generating images of an anterior or posterior segment of an eye is described. The system includes a light source, a controller, optics, a detector, and a processor. The light source generates a beam of light and is capable of operating in a posterior or an anterior segment imaging mode. In the posterior segment imaging mode, light source outputs light with a first spectral bandwidth of less than 120 nm and including wavelengths between about 1060 to 1070 nm. In the anterior segment imaging mode the light source outputs light with a second spectral bandwidth that is larger than 120 nm. The controller enables switching between the posterior or anterior segment imaging mode.

Abstract: An ophthalmic lens comprising: at least one first optical zone with a first axis, the at least one first optical zone being configured such that, in use with an eye, at least a portion of light passing through the at least one first optical zone is refracted to a first focal point on the first axis; and at least one second optical zone configured such that, in use with the eye, at least a portion of light passing through the at least one second optical zone is refracted to one or more focal points positioned off-axis relative to the first focal point and on at least one focal plane different than a focal plane corresponding to the first focal point; wherein the at least one second optical zone is configured such that the light extending beyond the one or more focal points provides extended depth of focus.

Abstract: Certain embodiments of the present invention are directed to therapeutic intervention in patients with eye-length-related disorders to prevent, ameliorate, or reverse the effects of the eye-length-related disorders. Embodiments of the present invention include methods for early recognition of patients with eye-length-related disorders, therapeutic methods for inhibiting further degradation of vision in patients with eye-length-related disorders, reversing, when possible, eye-length-related disorders, and preventing eye-length-related disorders. Additional embodiments of the present invention are directed to particular devices used in therapeutic intervention in patients with eye-length-related disorders.

Abstract: A mask for performing an eye exam of a subject includes one or more optically transparent sections for transmitting an incident light beam therethrough and incident on the subject's eye, in some embodiments, the one or more optically transparent sections are coated with an anti-reflective coating configured to reduce reflection of the incident light beam by the one or more optically transparent sections. In some embodiments, the one or more optically transparent sections may have a portion thereof that is tilted with respect to the incident light beam when the mask is optically interfaced with the docking portion of an ophthalmic instrument, such that the incident light beam forms a finite angle of incidence with respect to the corresponding portion of the optically transparent sections.

Abstract: An example device is configured to capture an image of an eye. The device includes a camera configured to capture the image of the eye. The device also includes: a first base configured to be moved along a first axis to position the camera to capture the image of the eye; a second base configured to be moved along a second axis to position the camera to capture the image of the eye; and a third base configured to be moved along a third axis to position the camera to capture the image of the eye.

Abstract: Disclosed herein are methods and apparatus for making a determination about an eye in ambient lighting conditions comprising detecting ambient light reflected out of an eye of a subject from a retina of the eye of the subject and making a determination about the eye of the subject based upon the reflected ambient light.

Abstract: The present disclosure provides electroretinography devices configured to detect biopotential signals from an eye of a subject. In some embodiments, the device is configured to prevent the subject's eyelids from closing over the device when placed in contact with the anterior surface of the subject's eye. In some embodiments, the device has a Young's modulus of no more than about 50 MPa. In some embodiments, the device includes a diffusing or refracting element configured to scatter, focus or diverge incident light. In other embodiments, the device includes a void through which incident light can enter the subject's eye without passing through any portion of the device.

Abstract: An endoscope light source device is constituted by a first light source unit that emits light in a first wavelength band, a second light source unit that emits light in a second wavelength band, a light path combining means for combining the light paths of the light emitted from the first and second light source units, and a light source control means for controlling light emission of the light source units separately. When the light source units are driven to emit light in a first mode, the respective wavelength bands of light are emitted at a first intensity ratio and combined with each other to obtain normal light, which is supplied to an endoscope.

Abstract: The invention is directed to a system for determining the refractive properties of an eye. The system includes a wavefront measurement device for measuring the refractive properties of the eye. The system is configured to have at least one measurement mode assigned to children, wherein the system has an input device configured to switch the system into one of the at least one measurement mode assigned to children. The system is further configured to alter at least one of a group including a default pupillary distance, a default cornea vertex distance, a default position of the wavefront measurement device, a default position and/or direction of a measurement ray of the wavefront measurement device, a default position of a forehead and chin rest assembly of the system and a fixation target when the system is switched into the one of the at least one measurement mode assigned to children.

Abstract: Methods and devices for accurate noninvasive measurement of blood analyte concentrations are disclosed. In an example process, optical properties of a blood vessel proximate to the surface of an exposed body part, for example, the sclera or the backside of the eye lid, is measured. Analyte concentrations are determined based on the measured optical properties.

Abstract: The present teaching relates to method, system, medium, and implementations for authenticating a user. An authentication session is first initiated to authenticate, via iris, a person claiming to be an authorized user, in which a first set of signals is randomly generated for controlling light strobing to be applied to the iris of the person for detecting liveness of the iris. A second set of signals is accordingly generated for controlling iris picture capturing synchronized with the light strobing. The light strobing is applied to the person via strobes generated based on the first set of signals and pictures of the iris of the person are acquired, based on the second set of signals, that are synchronized with the light strobing. Whether the person is live is then determined based on the synchronized pictures acquired when the light strobing is applied.

Abstract: A system tracks eye movement using optical coherence in a head mounted display. The system includes an illumination source configured to project low coherence interference light onto a portion of a user's eye. The system includes a scanning system to select an axial position within the illuminated portion of the user's eye. The system includes a detector configured to collect light reflected from the illuminated portion of the user's eye at the selected axial position, and the reflected light includes measurement data characterizing the illuminated portion of the user's eye. The system includes a controller configured to compare the measurement data with a trained baseline, and determine an eye position based the comparison.

Abstract: A device and method of ophthalmic diagnosis of lesions on retina utilizing a slit lamp apparatus with a pupil reader and at least one visible LED and one Infrared LED to detect a lesion on the retina of an eye.

Abstract: An apparatus for producing a fundus image includes: a processor and a memory; an illumination component including a light source and operatively coupled to the processor; a camera including a lens and operatively coupled to the processor, wherein the memory stores instructions that, when executed by the processor, cause the apparatus to: execute an automated script for capture of the fundus image; and allow for manual capture of the fundus image.

Abstract: Systems and methods for high-resolution, wide-angle viewing of a retina of an eye using an ophthalmic microscope that can view a high-resolution image of a retina formed using a wide field of view optical system. A wide field of view optical system can involve a first lens having a diffractive surface on at least one surface and a second lens housing in a shared housing. A wide field of view optical system can involve one or more lens formed from an optical grade polymer and manufactured at a cost that allows the lens to be disposable.

Abstract: Systems and methods for use in tri-spot point spread function imaging are provided that include a phase mask. The phase mask includes three partitions that each include a subset of the total area that is asymmetrical to other partitions. Each partition includes a phase delay ramp aligned along a phase delay axis, and includes a gradient of phase delays. Each phase delay axis is oriented in a different direction with respect to each other. Included is a source that outputs an excitation beam into a sample containing at least one light emitter that emits a radiation pattern when illuminated. Included is at least one sensor arranged to capture at least one image of the radiation pattern and a phase mask positioned between the at least one emitter and the at least one sensor. The phase mask is configured to produce a tri-spot point spread function.

Abstract: A method of determining at least one selection parameter for selecting an intraocular lens to be inserted into an eye; the method comprises reading, by a data processing system, data indicative of an axial position of at least a portion of an anterior surface of an at least partially empty capsular bag of the eye, relative to an optical axis of the eye. The method further comprises determining an axial position parameter, which is representative of the axial position of the portion of the anterior surface, depending on the data. The method further comprises determining the at least one selection parameter for selecting the intraocular lens depending on the determined position parameter.

Abstract: Light diffusing optical fibers for use in illumination applications and which have a uniform color gradient that is angularly independent are disclosed herein along with methods for making such fibers. The light diffusing fibers are composed of a silica-based glass core that is coated with a number of layers including both a scattering layer and a phosphor layer.