Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: A confocal scanner into which light from a light source is introduced via a multimode optical fiber includes: a disk unit that includes a rotary disk; and an optical system that irradiates the rotary disk with light from an emission end face of the optical fiber. The optical system includes an element that changes a size in which the emission end face of the optical fiber is projected onto the rotary disk.

Abstract: The present invention is directed to an indirect ophthalmoscopic system for imaging of the ocular fundus including a headband configured to hold a digital imaging device and a plus eyepiece lens in front of an eye of the examiner, with the plus eyepiece lens positioned in between the digital imaging device and the examiner's eye, such that the examiner is focused upon the display of the digital imaging device. The aperture of the digital imaging device receives light reflected from the ocular fundus of the patient's eye, emanating from the patient's pupil. The examiner examines the patient and composes the image of the ocular fundus directly in the display screen. In this way, what the examiner sees is captured by the digital imaging device. Stereoscopic imagery is obtained by optical means that create side-by-side virtual images of the aperture of the digital imaging device within the pupil of the eye.

Abstract: Portable lensmeters and portable lensmeter modules are disclosed. In one embodiment, a portable lensmeter module comprises a housing having an aperture formed therethrough and having a first slot formed therein for receiving and reversibly coupling to a lens; a light source disposed within the housing; and a microlens array disposed within the housing. The lens and the microlens array define an optical channel from the light source to the aperture when the lens is coupled to the housing; and a light detector of a mobile device is positioned adjacent to the aperture and at a focal point of the microlens array when the lensmeter module is mechanically coupled to the mobile device.

Abstract: The invention relates to a lighting device (100), which is equipped for fastening to a surgical instrument (200) or, by means of adapter (90; 91), to a body part (92), in particular a finger of a surgeon or of an operating room assistant, in order to serve as a light source during a surgical operation, in particular within a body cavity or organ cavity of genuine or traumatic origin and in other body regions that are difficult to access. At least one pin (20) pointing outward from the wall of the housing (10) is arranged on the housing (10) of the lighting device (100) in a wall area (30) directed toward the surgical instrument in the fastening position, which pin has a light emitting opening (40) at the distal end of the pin and is designed for passing through an opening (220) of the surgical instrument or of the adapter (90; 91) and thus establishing a form-closed or force-closed connection to the opening. The pin (20) is preferably movable in order to achieve optimal illumination of the operation site.

Abstract: A fundus image capture system operates to determine if the system has captured an image that identifies the fundus, a region of interest in the image, or the current field of view. According to the determination, the system can guide the user to operate the system to capture a desired fundus image.

Abstract: A multi-component method and device for improving vision for some with low vision conditions including age related macular degeneration (AMD) is disclosed. A plurality of co-pathological conditions that together make undistorted, clear and bright vision challenging are dealt with by managing the nature, amounts and patterns of light provided to the eye in a display embodiment. For example, a worn embodiment, in providing an improved image of the view ahead, modifies the frequency mix of incoming light, the relative intensities of light to different retinal locations and the color perception of the wearer while undistorting certain kinds of progressive distortion.

Abstract: A subjective optometry apparatus includes subjective measurement unit for subjectively measuring an optical characteristic of a subject eye, the subjective measurement unit including a calibration optical system that is disposed in an optical path of a light projecting optical system projecting a visual target luminous flux toward the subject eye and changes an optical characteristic of the visual target luminous flux. The subjective optometry apparatus includes objective measurement unit for objectively measuring the optical characteristic of the subject eye, the objective measurement unit including a measurement optical system that emits measurement light to a fundus of the subject eye and receives reflected light of the measurement light.

Abstract: Various embodiments of an eye imaging apparatus are disclosed. In some embodiments, the eye imaging apparatus may comprise a light source, an image sensor, a hand-held computing device, and an adaptation module. The adaptation module comprises a microcontroller and a signal processing unit configured to adapt the hand-held computing device to control the light source and the image sensor. In some embodiments, the imaging apparatus may comprise an exterior imaging module to image an anterior segment of the eye and/or a front imaging module to image a posterior segment of the eye. The eye imaging apparatus may be used in an eye imaging medical system. The images of the eye may be captured by the eye imaging apparatus, transferred to an image computing module, stored in an image storage module, and displayed in an image review module.

Abstract: Techniques are introduced to improve the ability of OCT to determine more accurately the nature of the flow of fluids in the eye, including faster measurements of the flow and a method to reduce geometric uncertainties due to eye movements.

Abstract: The present disclosure describes systems and methods to select fovea containing optical coherence tomography (OCT) images. The systems and methods described herein receive a plurality of OCT images. The portion of the OCT images are selected for further processing, where a line tracing the border between the retina and non-retina tissue is generated. A difference of the line is generated. Candidate OCT images are then generated responsive to the generated difference line. The lowest point among each difference lines generated for each of the OCT images is identified, and the OCT image to which the lowest point corresponds is identified as the fovea containing OCT image.

Abstract: A method for measuring the geometric parameters of the eye. These measurements, known by the term biometrics, are particularly significant for the calculation of intraocular lenses after previous refractive cornea surgery. OCT images and other images are recorded simultaneously, the intensity of the reflected light generated during the OCT image recordings being lower by a factor of 2, by a factor of 10 or by a factor of 100, than the intensity of the illumination light of the other image recordings. The solution provides a method for producing other image recordings, in addition to OCT recordings, in the form of representations of the sclera or of the fundus, or keratometric, topographic or biometric measurements, or even short image sequences, for instance, while aligning the device with the eye.

Abstract: In a method for interferometrically capturing measurement points of a region of an eye, a plurality of measurement points are captured by a measurement beam along a trajectory, wherein the same trajectory is passed over by the measurement beam in the region during at least a first iteration and a second iteration. The trajectory of the first iteration is rotated through an angle and/or displaced by a distance in relation to the trajectory of the second iteration in order to obtain a more homogeneous measurement point distribution.

Abstract: An ophthalmological apparatus includes a handle for manually holding and applying the ophthalmological apparatus, fastening abilities for fixing the ophthalmological apparatus at an eye, a light source, and a light projector for the focused projection of light pulses for punctiform tissue breakdown at a focal point in the interior of the eye tissue. The ophthalmological apparatus also includes a movement driver for moving the light projector. The movement of the light projector and therefore that of the focal point with the assistance of the movement driver permits a dimensioning of the optical projection system of the light projector which is substantially smaller than in the case of an ophthalmological apparatus where the focal point is moved exclusively by an optical projection system.

Abstract: An apparatus for the treatment and/or prevention of corneal diseases includes an applicator head. The applicator head includes a radiation source capable of exciting a non-toxic chromophore. A control is operable to activate the radiation source to radiate, wherein at least one of the following two conditions is met: the applicator head includes a sensor capable of measuring a signal dependent on a position of the applicator head relative to the cornea; or, the applicator head is configured to be in physical contact with the cornea. The control is operable to activate the radiation source to radiate depending on a signal measured by the sensor or to activate the radiation source when the applicator head touches the cornea, respectively.

Abstract: A six degree-of-freedom optical tracker system includes LEDs that are mounted on a structure, and are each configured to emit light. An LED controller is coupled to the LEDs and supplies drive current to each of the LEDs in a manner that causes the LEDs to sequentially and individually emit light. A single position sensing device that is spaced apart from each of the LEDs receives the light emitted from each of the LEDs and supplies position data for each LED. A processor receives the position data and determines the position and orientation of the structure relative to the single position sensing device.

Abstract: Sets, kits or stocks of anti-myopia lenses and methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than ?6D central refractive error. For example, a kit or set of lenses (50, FIG. 15) can have multiple parts or sub-sets each with a compartmented container with lenses arranged according to increments of central corrective power. The lenses of the first part have four steps of peripheral power or defocus to provide therapeutic effect and, while the lenses of the second part also have four steps, the level of therapeutic effect is higher. Other examples of sets, kits and stocks, as well as examples of lenses themselves, are disclosed together with methods of use.

Abstract: A method for detecting objects (28) of interest comprises: receiving gaze tracking data (30) of a person looking at a collection of objects (28), the gaze tracking data (30) comprising information, at which points the person is looking; determining a map (42) of objects in the field of view of the person, the map (42) of objects indicating, at which position (44) an object in the collection of objects is arranged; determining gaze interaction events (48) for objects in the collection of objects by matching the gaze tracking data (30) to the map (42) of objects, wherein a gaze interaction event (48) for an object indicates that a specific gazing interaction has occurred with respect to the object; determining category characteristics (56) for at least those objects (28) having gaze interaction events (48), wherein a category characteristic (56) describes the object with respect to a specific object category (58); and determining at least one category characteristic (56) of interest in at least one object categ

Abstract: A method of screening a pupil of a subject to determine whether the pupil reflex resembles a canonical pupil reflex is disclosed. The method comprises the steps of stimulating the pupil with a stimulus source, such as a pupilometer and determining whether one of various pupillary response conditions is met.

Abstract: A method of automatically detecting a retinal feature using an ophthalmic imaging system can include: acquiring an optical coherence tomography (OCT) image of a retina; segmenting the OCT image; generating a metric based on the segmented OCT image; detecting the retinal feature based on the metric; and providing an indication of the detected retinal feature to a user. An ophthalmic imaging system can include: an OCT system configured to acquire an image of a retina; a computing device coupled to the OCT system and configured to segment the image, generate a metric based on the segmented image, and detect a retinal feature based on the metric; and an audio/visual/tactile device in communication with the computing device and configured to provide at least one of an audio, visual, and tactile indication of the detected retinal feature to a user.

Abstract: From OCT-measured data, only the image data of the choroidal vascular network present in the layer of the choroidal layer is selectively extracted, thereby accurately obtaining the thickness of the choroidal vessels and thickness of the choroidal vascular network from the image data, to allow for quantitative evaluation of the choroidal vascular network. The optical coherence tomography apparatus has an optical coherence tomography device, and a computer that processes the three-dimensional OCT tomographic images obtained based on the OCT-measured data acquired by the optical coherence tomography device. The computer functions as a means for selectively separating out only the images of the choroidal vessels from the three-dimensional OCT tomographic images to acquire image data of the choroidal vessels, and also as a means for obtaining the data to be used in the quantitative evaluation of the shape of the choroidal vessels based on the image data of the choroidal vessels.

Abstract: An information processing apparatus includes: a light emitting unit configured to emit light; an optical unit configured to induce an optical influence to the light from the light emitting unit, the optical unit having an astigmatic lens configured to generate astigmatism with a plurality of focal lengths; a detecting unit configured to detect the light emitted in the light emitting unit, radiated outside through the optical unit, and reflected by an object; and a measuring unit configured to measure a distance to the object based on astigmatism generated in the reflection light detected in the detecting unit.

Abstract: A head mounted display (HMD) comprises an eye tracking system configured to perform a calibration process using an eye tracking system of the HMD that includes determining a pupillary axis and/or determining an angular offset between the pupillary axis and the eye's true line of sight. The eye tracking system obtains an eye model captures images of the user's pupil while the user is looking at a target or other content displayed on the HMD. In some embodiments, the calibration process is based on a single image of the user's eye and is performed only once. For example, the process can be performed the first time the user uses the HMD, which stores the calibration data for the user in a memory for future use.

Abstract: An image processing device comprises an enhancement processing unit that enhances a speckle pattern in an ocular fundus tomographic image. A region-of-interest setting unit sets a desired region in the ocular fundus tomographic image with the enhanced speckle pattern as a region-of-interest, and a feature value extracting unit extracts a feature value of the speckle pattern in the region-of-interest. A disease determining unit makes disease determination for an ocular fundus on the basis of the feature value, and a mapping unit maps, in the ocular fundus tomographic image, a site of the ocular fundus that is determined to have a disease.

Abstract: An endo-optic illuminator has a compartment, a divider within the compartment, and a fiber optic cable in optical communication with the divider and with the light source of a microscope. The fiber optic cable transmits the light through its length. The cable has two ends: a tip and a base. A user then positions the cable to emit light with the tip proximate a patient's eye. Opposite the tip, the base connects the cable to the light source. The divider redirects light from the light source into the base of the fiber optic cable and then onward to illuminate its tip. The divider includes a prism, beam splitter, mirror flip, occluder, shutter, and the like. The fiber optic cable transmits light with less than a 10% loss of candlepower along its length. The illuminator replaces a second separate light source currently used by ophthalmologists.

Abstract: Lighting device (10) having a support (11), a plurality of emitting elements (12) adapted to emit light, fixed to the support (11) and each having an emission direction (A) radial to a predefined optical axis (B). The lighting device (10) is provided with a reflection surface (13) facing the emitting elements (12) and configured to reflect the light emitted in use by the latters in a direction parallel to the optical axis (B).

Abstract: In the context of a method for the analysis of image data representing a three-dimensional volume of biological tissue, the image data comprises a first image representing the volume at a first point in time and a second image representing the volume at a second point in time being different from the first point in time.

Abstract: Wavefront measurements of eyes are typically taken when the pupil is in a first configuration in an evaluation context. The results can be represented by a set of basis function coefficients. Prescriptive treatments are often applied in a treatment context, which is different from the evaluation context. Hence, the patient pupil can be in a different, second configuration, during treatment. Systems and methods are provided for determining a transformed set of basis function coefficients, based on a difference between the first and second configurations, which can be used to establish the vision treatment.

Abstract: A system and method for rejecting afocal light collected from an in vivo human retina is disclosed. The system may include a detector, a server system being in communication with the detector and a memory system with a rejection of collected afocal light and a disk having an optointerruptor and a motor, which is speed controlled via a non-transitory storage media. The method includes utilizing a series of optical shapes or codes, similar to other structured illumination systems, illuminating the series of optical shapes or codes several times, collecting and processing the series of optical shapes or codes yielding measurements of optical noise and optical signal and subtracting the noise and signal from the final image.

Abstract: An image processing apparatus has an acquisition unit which acquires a second tomogram related to a first tomogram of an eye to be examined based on position information of an eye fundus of the eye to be examined according to a predetermined rule; and a display control unit which displays the first tomogram and the second tomogram on a display unit.

Abstract: Provided is a slit lamp microscope capable of controlling irradiation of slit light and background illumination light interlockingly. Embodiment includes a main illumination system, background illumination system, observation system and controller. The main illumination system includes a first light source unit that outputs first light and slit forming unit that forms a slit with changeable width, and illuminates an eye with the first light having passed through the slit. The background illumination system includes a second light source unit that outputs second light, and illuminates a peripheral area of an eye area irradiated with the first light. The observation system includes an eyepiece lens, imaging device, and group of optical elements that guides reflected light of the first light and reflected light of the second light from the eye to the eyepiece lens and imaging device. The controller interlockingly controls the main illumination system and second light source unit.

Abstract: A method for detecting a disease such as Alzheimer's disease by analysis of retinal vasculature is disclosed. The method for detecting a disease by analysis of retinal vasculature may include applying a combination of optical retro mode illumination techniques to acquire a plurality of amyloid beta plaques and drusen images that are too small to be seen with other imaging modalities. The disease may also be detected with a non-transitory computer storage media having instructions stored thereon which, when executed, execute the method for detecting a disease by analysis of retinal vasculature. The method may track changes in lumen thickness, plaque, size, area and density of the disease by analysis of retinal vasculature over a predetermined period of time.

Abstract: Patterned laser treatment of the retina is provided. A visible alignment pattern having at least two separated spots is projected onto the retina. By triggering a laser subsystem, doses of laser energy are automatically provided to at least two treatment locations coincident with the alignment spots. All of the doses of laser energy may be delivered in less than about 1 second, which is a typical eye fixation time. A scanner can be used to sequentially move an alignment beam from spot to spot on the retina and to move a treatment laser beam from location to location on the retina.

Abstract: An ophthalmic instrument for the application of laser radiation in a patient's eye, particularly for the examination and/or surgical laser treatment of the cornea and the lens of the eye, includes a femtosecond laser, an objective and optical assemblies. The optical assemblies are arranged in front of the objective, and selectively vary the focus position in the coordinate direction X,Y and Z either within the region of the cornea or within the region of the lens of the eye. The objective or at least one lens group is movable relative to the eye. The variation of the position of the lens group objective shifts the focus position from the cornea to the lens of the eye and vice versa.

Abstract: An eye-protection lamp comprises: a lampshade; a light emitting body, arranged inside the lampshade; a first photosensitive sensor, for detecting light intensity of the light emitting body; a second photosensitive sensor, for detecting ambient light intensity; a distance detecting device, for detecting a first distance (L1) between the light emitting body and a desktop under the lamp; an eye recognition device, for recognizing eyes and detecting a position of the eyes; a control unit, for adjusting the light intensity of the light emitting body according to the detected light intensity of the light emitting body, the ambient light intensity, the first distance (L1), and the position of the eyes. A light intensity adjusting method of an eye-protection lamp is further provided.

Abstract: Provided herein are ophthalmic phototherapy devices and associated phototherapy methods for promoting healing of damaged or diseased eye tissue. An ophthalmic phototherapy device includes a light emitting mechanism for transmitting light of at least one preselected wavelength to the eye tissue. An ophthalmic phototherapy method includes directing light of at least one wavelength for a selected period of time to a portion of damaged or diseased eye tissue, whereby the light transmitted to the damaged or diseased eye tissue stimulates cellular activity in the eye tissue to promote healing.

Abstract: Aspects of the present invention relate to methods and systems for imaging, recognizing, and tracking of a user's eye that is wearing a HWC. Aspects further relate to the processing of images reflected from the user's eye and controlling displayed content in accordance therewith. Aspects further relate to determining health conditions of the user based on eye imaging technologies.

Abstract: A laser system including: a laser source operable to emit a first laser beam having a first operating wavelength and a second laser beam having a second operating wavelength; a fiber optic cable to guide and homogenize the first and second laser beams; an expander to increase the diameter of the first and second laser beams; a cylinder to guide the first and second laser beams and limit respective diameters of the first and second laser beams, wherein the cylinder is positioned after the expander on an optical path of the laser beam; a first optical system to collimate the first and second laser beams, wherein the optical system is positioned after the cylinder on the optical path of the first and second laser beams; a spot-size selector comprising a plurality of apertures, wherein the spot-size selector is positioned after the first optical system on the optical path of the first and second laser beams; and a second optical system to focus the first and second laser beams on a tissue of the patient.

Abstract: Geographic atrophy of the eye can be detected and measured by imaging the eye at a depth greater than the retinal pigment epithelium (RPE) at a plurality of locations of the eye, for example, using optical coherence tomography (OCT); determining a ratio of the intensities of imaging signals of a retinal layer(s) with respect to the intensity of imaging signals of a sub-RPE layer(s) at each location; determining representative values based at least in part on the determined ratios; generating a map of the representative values; and identifying diseased areas from the map. Contours and binary maps may be generated based on the identified diseased areas. The size and shape of the identified areas may be analyzed and monitored over a period of time.

Abstract: Systems and methods for improving ophthalmic imaging by correlating the location of a measurement on the pupil of the eye with a quality of the measurement and further controlling subsequent measurements based on the quality are presented. Aspects of the invention include obtaining optical coherence tomography (OCT) measurements through cataracts or other media opacities, obtaining B-scans with minimized tilt, and automated OCT data acquisition of select structures in the eye. Embodiments of the invention directed towards imaging tissues with angle dependent layer contrast and mapping the size and location of cataracts in the eye are also described.

Abstract: To evaluate the accommodation function of an eye in detail, an accommodation function evaluation apparatus includes an accommodative stimulus applying unit, a measurement unit, and an analyzer. The accommodative stimulus applying unit is configured to apply an accommodative stimulus to the eye. The measurement unit is configured to perform optical coherence tomography for a target site in the eye including at least part of the crystalline lens. The analyzer is configured to analyze data obtained by the optical coherence tomography of the eye, to which the accommodative stimulus is being applied, to generate evaluation information related to the accommodation function of the eye.

Abstract: An adaptive optical apparatus includes a wavefront correction unit configured to correct a wavefront aberration, a first scanning unit configured to be arranged to be optically almost conjugate to the wavefront correction unit, and scan light on an object in a first direction, a second scanning unit configured to be arranged to be optically almost conjugate to the wavefront correction unit, and scan light on the object in a second direction perpendicular to the first direction, and an optical element arranged in an optical path between the wavefront correction unit and the first scanning unit and arranged in an optical path between the first scanning unit and the second scanning unit.

Abstract: An eye imaging apparatus can include a housing, an optical imaging system in the housing, and a light source in the housing to illuminate an eye. The optical imaging system can include an optical window at a front end of the housing with a concave front surface for receiving the eye as well as an imaging lens disposed rearward the optical window. The apparatus can comprise a light conditioning element configured to receive light from the light source and direct said light to the eye. The apparatus can further include an image sensor in the housing disposed to receive an image of the eye from the optical imaging system. In various embodiments, light conditioning element includes at least one multi-segment surface. In some embodiments, the housing is provided with at least one hermitic seal, for example, with the optical window. In some embodiments, time sequential illumination is employed.

Abstract: The invention provides a system and method for obtaining ophthalmic measurements whereby the inventive device is configured to be head mountable, automatically axially length aligned with a selected target, and laterally aligned so that light from an OCT source enters through the pupil of the eye under test. The frame of the head mountable OCT is customizable, capable of analyzing both the left and right eye of a subject. The inventive device can be operated by the person undergoing test. Embodiments include mechanisms for eye fixation, lateral, angular and depth scanning of target regions. A variety of embodiments are taught, including the scanning of both eyes of a subject at substantially the same time, and a configuration of a photonic module coupleable with a plurality of frames. Embodiments include a variety of OCT sources, such as MRO, swept source, time domain, and spectral domain.

Abstract: A system and apparatus for increasing the amplitude of accommodation and/or changing the refractive power and/or enabling the removal of the clear or cataractous lens material of a natural crystalline lens is provided. Generally, the system comprises a laser, optics for delivering the laser beam and a control system for delivering the laser beam to the lens in a particular pattern. There is further provided a range determining system for determining the shape and position of the lens with respect to the laser. There is yet further provided a method and system for delivering a laser beam in the lens of the eye in a predetermined shot pattern.

Abstract: A method for quantifying a blood vessel reflection parameter associated with a biological subject, the method including, in at least one electronic processing device determining, from a fundus image of an eye of the subject, edge points of at least one blood vessel in a region near an optic disc, processing the fundus image, at least in part using the edge points, to identify blood vessel edges and central reflex edges, determining blood vessel and central reflex parameter values using the blood vessel edges and determining a blood vessel reflection parameter value at least partially indicative of blood vessel reflection using the blood vessel and central reflex parameter values.

Abstract: An ophthalmic surgical system can include a light source configured to generate a light beam and a filter wheel disposed between the light source and an intraocular illumination device. The filter wheel can include an unfiltered area, a first filtered area, and a second filtered area. The first and second filtered areas can limit transmission of certain wavelengths of the light beam to the intraocular illumination device. The system can include an actuator configured to selectively move the filter wheel to cause the light beam to pass through the unfiltered area, the first filtered area, and/or the second filtered area. The system can include a computing device configured to provide a control signal to the actuator. The computing device can be configured to provide a control signal to the actuator based on a beam location, a beam composition, an exposure time, and/or a limited visibility condition.

Abstract: A system includes one or more optical emitters, a transceiver, and a body mountable device. The optical emitters emit light and are configured to be used in luminaires. The transceiver is coupled to receive input data from a data network and coupled to selectively modulate the optical emitters to transmit the optical data. Selectively modulating the optical emitters is in response to the input data. The body mountable device includes a photodetector coupled to receive the optical data and processing circuitry configured to initiate an action in response to receiving the optical data from the photodetector.

Abstract: Disclosure herein concerns a method that includes illuminating a user's eye with an illumination source in a head-worn display, capturing an image of the user's eye with an eye camera in the head-worn display, wherein the image includes an eye glint produced by light from the illumination source that is reflected from a surface of the user's eye, determining a size of an eye glint in the captured image, and identifying a change in focus distance for the user's eye in correspondence with a change in the size of the eye glint.

Abstract: Aspects of the present invention relate to methods and systems for imaging, recognizing, and tracking of a user's eye that is wearing a HWC. Aspects further relate to the processing of images reflected from the user's eye and controlling displayed content in accordance therewith. Aspects further relate to determining health conditions of the user based on eye imaging technologies.