Abstract: A spectral filtering apparatus and method is presented, which enables the functions of hyperspectral imaging to be performed with increased speed, simplicity, and performance that are required for commercial products. The apparatus includes a photosensitive array having a plurality of photosensitive elements such that different subsections of photosensitive elements of the array receive light of a different wavelength range of a characteristic spectrum of a target, and output electronics combines signals of at least two photosensitive elements in a subsection of the array and outputs the combined signal as a measure of the optical energy within a bandwidth of interest of the characteristic spectrum.

Abstract: A method and apparatus are provided for Raman imaging of carotenoids and related chemical substances in biological tissue, such as macular pigments. The method and apparatus utilize the technique of resonance Raman spectroscopy to produce an image of the levels of carotenoids and similar substances in tissue. In this technique, light is directed upon the area of tissue which is of interest such as the retina of an eye. A small fraction of the scattered light is scattered inelastically, producing a carotenoid Raman signal which is at a different frequency than the incident light. The Raman signal is collected, filtered, and analyzed to determine the spatial position and intensity of the Raman signals in the inelastically scattered light. An image of the Raman signals is then produced on an output device, with the image representing the spatial distribution and concentration level of carotenoids in the tissue.

Abstract: Briefly, in accordance with one embodiment of the invention, the intensity of the signals from surface enhanced Raman spectroscopy may be increased by using lithium chloride as an enhancer to activate a metallic structure used for surface enhanced Raman spectroscopy. The increased signal intensity may allow surface enhanced Raman spectroscopy to be utilized to detect individual analytes such as nucleotides, for example in DNA sequencing without requiring a dye or radioactive label.

Abstract: System for detection and analysis of gas samples in fieldable real-time Differential Mobility Spectrometry (DMS) chemical sensor system which uses non-radioactive ion source for monitoring and detecting NOx emissions; provides reliable methods for detecting and monitoring of anthropogenic sources of NOx; also detection of NO in exhaled breath for patient health diagnosis.

Abstract: The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical fibers in the bundle are utilized as a source of radiation, these two fibers are at two different angles from normal. At least one of the other optical fibers is utilized as a detector for the reflected radiation, or alternatively an image guide can be used as the detector. The device of the invention can be part of an external or internal system that can include a light source, the device, a multiplexer, a spectrometer, and a computer for data analysis. The method of the invention allows for the detection and monitoring of general inflammation of the oral epithelium. The inflammation of the epithelium can be detected or monitored to diagnose diseases of the oral epithelium, monitor such diseases, monitor treatment of such diseases, or pre-screen for and monitor preventative treatments of such diseases.

Abstract: Apparatus and methods for spatially resolved Raman detection of molecules indicative of the borders of lesions with normal tissue are disclosed. A region of biological tissue was illuminated with monochromatic light. A Raman shifted light signal is detected from endogenous molecules in the region, the molecules being spatially organized in a localized first area of the region. These molecules are indicative of a border between normal tissue and a lesion. The Raman shifted light signal is then spatially resolved in at least one direction.

Abstract: The optical sensor contains an optical waveguide (1) with a substrate (104), waveguiding material (105), a cover medium (106) and a waveguide grating structure (101-103). By means of a light source (2), light can be emitted to the waveguide grating structure (101-103) from the substrate side and/or from the cover medium side. (101-103). With means of detection (11), at least two differing light proportions (7-10) radiated from the waveguide (1) can be detected. For carrying out a measurement, the waveguide can be immovably fixed relative to the light source (2) and the means of detection (11). The waveguide grating structure (101-103) itself consists of one or several waveguide grating structure units (101-103), which if so required can be equipped with (bio-)chemo-sensitive layers. The sensor permits the generation of absolute measuring signals.

Abstract: Apparatus and methods for spatially resolved Raman detection of calcification in tissues are disclosed. A region of soft non-arterial biological tissue is illuminated with monochromatic light. A spatially organized first area of calcified tissue is then detected in the region by detecting a Raman shifted light signal. The Raman shifted light signal is spatially resolved in at least one direction.

Abstract: A model for determining the type of soil, the water content of a soil, and the soil properties, and a soil measurement data storage portion (60) to store therein measurement data necessary to carry out the model and correlated with specific measurement conditions are provided. The water content is measured by a water content measuring portion (57) on the basis of the measurement data fed from a soil sensor (S). The type of soil is determined by a feature extracting portion (56) and a type-of-soil determining portion (58), and the determined type of soil is sent to a determining portion (59). The determining portion (59) determines corresponding conditions and a model according to the type of soil and water content of the measured place received and sets them in a predetermined processing portion.

Abstract: Minute amounts of material, such as a contaminant, are detected, classified and located using a single procedure that eliminates the need for using complex and sometimes redundant instrumentation setups, multiple (and sometimes overlapping) analytic processes, or both. In one embodiment, a series of processing steps enables one to detect, classify, and localize minute amounts of particular elements, e.g., contaminants, in material being tested. Data sets, suitable for characterizing components of samples at least spectrally and spatially, are collected from at least one uncontaminated sample of material (the “baseline” or “control”) and a sample of material under test (MUT) that may contain contaminants. Comparison of these data sets, using the procedures of the present invention, enables ready classification of minute amounts of material in any sample.

Abstract: Minute amounts of material, such as a contaminant, are detected, identified and located using a single procedure that eliminates the need for using complex and sometimes redundant instrumentation setups, multiple (and sometimes overlapping) analytic processes, or both. In a preferred embodiment, a series of processing steps enables one to detect, identify, and localize minute amounts of particular elements, e.g., contaminants, in material being tested. Data sets, suitable for characterizing components of samples at least spectrally and spatially, are collected from at least one uncontaminated sample of material (the “baseline” or “control”) and a sample of material under test (MUT) that may contain contaminants. Comparison of these data sets, using the procedures of the present invention, enables ready identification of minute amounts of material in any sample. The use of existing conventional procedures may require that multiple sets of data be taken or multiple processes be applied.

Abstract: A system for the detection of bacteria based on bacteria-antibody complexes. Bacteria attached to antibody are detected with resonance Raman spectroscopy. The bacteria are detected directly in a great numerical excess, e.g. 100 to 10,000 of antibody molecules. A sample to be tested is placed in a medium, the medium containing antibodies attached to a surface for binding to a specific bacteria to form an antigen to antibody complex. The medium is contacted with a beam of light energy. The bacteria, as a lower resonance enhanced Raman backscattered energy, is analyzed for the presence or absence of the bacteria.

Abstract: A method and system for diagnosing pathology, such as carcinoma, in a biological sample identifies presence of pathology based on the existence of an infrared markers in the extracellular material, rather than cells, in the biological sample. In the case of breast cancer diagnosis, an effective marker is a baseline slope of a 1280 cm?1 band in the infrared spectra of connective tissue, with normal biopsy samples exhibiting a positive slope and cancerous samples showing a relatively flat baseline. Infrared spectroscopy, both microscopic and macroscopic, may be used to identify a sample region containing extracellular material and to collect infrared absorbance data, from which the existence of the pathology marker is determined.

Abstract: Complex multidimensional datasets generated by digital imaging spectroscopy can be organized and analyzed by applying software and computer-based methods comprising sorting algorithms. Combinations of these algorithms to images and graphical data, allow pixels or features to be rapidly and efficiently classified into meaningful groups according to defined criteria. Multiple rounds of pixel or feature selection may be performed based on independent sorting criteria. In one embodiment sorting by spectral criteria (e.g., intensity at a given wavelength) is combined with sorting by temporal criteria (e.g., absorbance at a given time) to identify microcolonies of recombinant organisms harboring mutated genes encoding enzymes having desirable kinetic attributes and substrate specificity. Restriction of the set of pixels analyzed in a subsequent sort based on criteria applied in an earlier sort (“sort and lock” analyses) minimize computational and storage resources.

Abstract: Serum emission can be used as the first test to detect metabolic disorders in mammals. When changes in emission of the serum from patients with different pathological conditions were characterized, a difference was seen for patients with diseases such as cancer, thyroid disorder, arthritis, diabetes, coronary artery disease (CAD), hypertension, CFS (chronic fatigue syndrome), and fibromyalgia. The level of emission was enhanced or diminished and correlated with the level of energy metabolism and the level of metabolic rate. The method can also be used for risk assessment, to identify whether a treatment is working or to follow the course of a treatment, and to identify changes in energy levels due to stress, etc.

Abstract: The present invention relates to a spectrometer module comprising an input, for receiving an incoming optical signal, a variable differential group delay (DGD) element, for applying a variable birefringence retardation to said incoming optical signal, and a detector unit for detecting the power of a signal exiting said variable DGD element, having a defined state of polarization. It also relates to a monitor module, a monitoring unit and a monitoring system, comprising such a spectrometer module for use in monitoring an optical network. Further, the invention relates to a spectrometer device, for spectrometry purposes, comprising a spectrometer module as stated above.

Abstract: A spectrophotometer and spectrophotometry method, using a precision drive at a photodiode array which precisely moves the photodiode array by a distance equal to the physical interval between the photodiodes of the photodiode array so that the spectrophotometer and spectrophotometry method primarily measures light intensities of incident light by the photodiode array, and when precisely moves the photodiode array using the drive by the distance equal to the physical interval between photodiodes of the photodiode array, measures the light intensities of the incident light at desired positions corresponding to the intervals.

Abstract: The invention is concerned with a method for the determination of the charging state of filtrates of fiber masses used in the manufacturing of paper and cardboard. In the method, a sample is filtrated from fibers through a filter, and indicator color is added to the filtrate. The absorbance of the filtrate is measured and the charging state of the solution is read from an earlier made calibration curve that corresponds to the measured absorbance. In the first embodiment of the invention, the calibration curve is made by taking a sufficient amount of samples from the same anionic sample and such different known amounts of cationic agent are added to these samples, that at least a part of the samples are cationic and at least a part of the samples are anionic. The charging states of the filtrated samples are determined in a previously known way, e.g.

Abstract: In measuring a spectral irradiance distribution of light, light is irradiated to n (natural number) light-transit sections, which respectively have n kinds of given optical characteristic coefficients, and s (natural number) optical sensors, which respectively have s kinds of given spectral sensitivities, receive the light via the n light-transit sections and detects individual responses for the received light. Then a calculating section calculates m (natural number) spectral irradiances for m kinds of wavelengths as a spectral irradiance distribution based on linear formulae established between the optical characteristic coefficients, the spectral sensitivities, (n×s) responses for the light obtained by the s optical sensors, and the spectral irradiance distribution of the light.

Abstract: A tunable optical filter for simulating the waveband spectrums of selected substances. The filter includes an optical waveguide with a core material for transmitting light energy and a nominal core refractive index for the core material. Predetermined periodic variations are formed in the core material of the optical waveguide between the input and output ends that alter the core refractive index of the waveguide at the location of the periodic variations. Depending upon the periodic variations, the waveguide produces a predetermined reference waveband spectrum output that matches the waveband spectrum of a selected substance. A modulator is coupled to the waveguide to selectively modulate the periodic variations to intermittently shift the reference waveband spectrum output to fine tune the filter and reduce signal noise.

Abstract: A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and exciting fibers and means for detecting, collecting and measuring fluorescent signals in communication with the collecting fiber. The probe and the collecting and exciting fibers are configured to focus paramagnetic microspheres attached to antigen/antibody/optically labeled complexes in a predetermined pattern in the field of view of the collecting fiber while blocking background interference.

Abstract: A rugged, miniature, spectroscopic gas analyzer apparatus for rapid, non-invasive, multi-component breath monitoring and analysis and subsequent determination of Q or other medical diagnostic applications. The system is comprised of one or more IR emitters focussed by optical elements through a low volume sample cell receiving a sample input of a patient's breath for analysis. The patient either at rest or during exercise, inhales C2H2—SF6 mixtures (balance of oxygen and nitrogen) which is subsequently monitored upon exhalation for CO2, H2O, C2H2, and SF6 which can be employed to determine Q directly and accurately. Measurements are performed in real-time or via post-processing of stored original data. Due to its small size, ruggedness, and low power consumption, the monitor can conveniently be employed in the field or data can also be retrieved remotely using telemetry.

Abstract: A top surface of a wafer is provided with an n-type source region, an n-type drain region, and an n-type semiconductor region. Dry etching using a plasma is performed with respect to an interlayer insulating film deposited on the wafer to form openings reaching the respective regions, followed by light etching for removing a damaged layer. In this case, exciting light is supplied intermittently to the n-type semiconductor region. The progression of the removal of the damaged layer and the stage of development of a newly damaged layer are sensed by monitoring the change rate of the intensity of reflected probe light in the presence and absence of the exciting light, resulting in the formation of a semiconductor device having low and equal contact resistance. In-line control using optical evaluation enables the implementation of semiconductor devices with excellent and consistent properties.

Abstract: Spectrographic instruments at remote site locations measure near infrared absorbance spectra for unknown materials and transmit the absorbance spectra to a central web site where, the measurements are standardized to be the same as if they were measured by a master instrument. The standardized absorbance spectra are then compared with a library of spectra stored at the central web site to select a subset of absorbance spectra from the library which most closely correlate with the absorbance spectrum received from the remote sites. The library spectra are obtained from measurements on materials, the measurable characteristics of which are known. From the selected subset, equations are developed relating the measurable characteristics of the unknown material to the absorbance spectra and from these equations, the measurable characteristics of the unknown materials are determined. The results of this analysis are then transmitted back to the remote site locations electronically.

Abstract: By using a reconstruction algorithm, based on the spectral characteristics of the illumination source and a color sensing system, a spectral curve reconstruction device converts measurements from a non-fully illuminant populated color sensor into a fully populated spectral curve. This is done using a spectral measurement system model, which may use basis vectors.

Abstract: An apparatus for measuring a glucose concentration is noninvasive, accurate, and compact. The apparatus includes a detection unit (10) and a principal component analysis (PCA) unit (20). The detection unit includes a light source (11) to emit mid-infrared light, an ATR prism (12) to receive the mid-infrared light with a measuring object placed on the ATR prism, and a spectrum detector (13) to detect an absorption spectrum from the mid-infrared light from the ATR prism. The PCA unit includes a loading memory (24) to store a glucose corresponding loading and a personal data memory (28) to store personal data in the form of a calibration curve. According to the detected absorption spectrum, stored loading, and stored personal data, the PCA unit computes a glucose concentration of the measuring object.

Abstract: Device for determining a desired contour of a ground surface, for instance a road surface, relative to the actual contour of that ground surface, at least comprising measuring unit for generating along a determined distance from a ground surface actual values for the height and position of a number of points of that ground surface relative to a determined reference point, wherein the measuring unit comprise a laser light source which can be placed at a measuring point above the ground surface and which is adapted to generate a laser beam moving over the determined distance from the ground surface, sensor for detecting the laser beam reflected by the ground surface to the measuring point, time-measuring unit for determining the transit time of said laser beam between the laser light source and the sensor, and processing system for generating from signals from the laser light source, the sensor and the time-measuring unit of actual values for the height and the position of a number of points of this ground

Abstract: A system and method for classifying tissue by application of discriminant analysis to spectral data. Spectra are recorded as amplitudes at a series of discrete wavelengths. Pluralities of reference spectra are recorded for specimens having known conditions. The reference spectra are subjected to discriminant analysis to determine wavelength regions of interest for the analysis. A plurality of amplitudes are selected for the analysis, and are plotted in an N-dimensional space. For each plurality of reference spectra corresponding to a specific known condition, a characteristic point is determined and plotted, the characteristic point representative of the known condition. A test spectrum is recorded from a test specimen, and the plurality of amplitudes corresponding in wavelength to the wavelength regions of interest are selected. A characteristic point in N-dimensional space is determined for the test spectrum.

Abstract: A device and a method enable the rapid, quantitative evaluation of a large collection of ligands for binding affinity with a certain immobilized receptor, the improvements being that binding pan be detected without the need for a label and that binding is carried out in solution phase at a high rate. The instrument has at least two embodiments, one is based on a sensitive absorption photometer and the other on a sensitive light scatter photometer operating at a specific resonance wavelength, &lgr;R, of small, metallic, colloidal particles. The resonance is present in small particles having a complex refractive index with real part n(&lgr;) approaching 0 and imaginary part k(&lgr;) approaching 2 simultaneously at a specific wavelength &lgr;R. The particles are substantially spherical and substantially smaller than &lgr;R. The receptor is immobilized on a suspension of such particles and ligand binding is detected by a change in optical absorption or light scatter at the resonance wavelength.

Abstract: Optical spectroscopy for brain tumor demarcation was investigated in this study. Fluorescence and diffuse reflectance spectra were measured from normal and tumorous human brain tissues in vitro. A fluorescence peak was consistently observed around 460 nm (±10 nm) emission from both normal and tumorous brain tissues using 337 nm excitation. Intensity of this fluorescence peak (F460) from normal brain tissues was greater than that from primary brain tumorous tissues. In addition, diffuse reflectance (Rd) between 650 nm and 800 nm from white matter was significantly stronger than that from primary and secondary brain tumors. A good separation between gray matter and brain tumors was found using the ratio of F460 and Rd at 400 nm-600 nm. Two empirical discrimination algorithms based on F (400 nm-600 nm), Rd (600 nm-800 nm), and F (400 nm-600 nm)/Rd (400 nm-600 nm) were developed. These algorithms yielded an average sensitivity and specificity of 96% and 93%, respectively.

Abstract: A method for determining magnitude and direction of spectral channel drift for several consecutive spectral regions over a wide spectral range. According to the method of the present invention, in-field testing of a spectral filter sequentially irradiated by two blackbody sources is performed to generate a response function of the spectral filter. The response function is ensemble averaged to reduce any noise. Background radiance is then removed to produce a smoothed spectral transmittance function of the spectral filter. The first derivative function of the smoothed spectral transmittance function is determined. The first derivative function is separated into spectral band regions having +/− N pixels on either side of the function minima. The value of N is selected to optimize the detection algorithm sensitivity to change while extending the limit of spectral shift magnitude.

Abstract: A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and exciting fibers and means for detecting, collecting and measuring fluorescent signals in communication with the collecting fiber. The probe and the collecting and exciting fibers are configured to focus paramagnetic microspheres attached to antigen/antibody/optically labeled complexes in a predetermined pattern in the field of view of the collecting fiber while blocking background interference.

Abstract: The present invention provides a hyperspectral imaging apparatus and methods for employing such an apparatus for multi-dye/base detection of a nucleic acid molecule coupled to a solid surface.

Abstract: An integrated-optic spectrometer is disclosed for analyzing the composition of light reflected off a sample under analysis. In a simplified embodiment, the spectrometer includes a buffer, located on the top of a substrate, which is etched to create a diffraction grating having grating lines. The diffraction grating and grating lines are formed to provide diffraction of discrete wavelengths of light, while providing for maximum transmission of non-diffracted wavelengths. A waveguide is fabricated on top of the etched buffer through which the reflected light is directed. A photodiode detector array is located above the waveguide into which the diffracted wavelengths are diffracted, providing an analysis of the composition of the reflected light. A clad encompasses the integrated-optic spectrometer, thereby providing protection from outside interference.

Abstract: Systems and methods for the multispectral imaging of skin tissue enables automatic characterization of the condition of a region of interest of the skin, based on direct digital imaging of the region of interest or the digitization of color photographic slides of the region of interest, illuminated by appropriately filtered light. Preferably, a digital image at a low spectral band is automatically segmented and that segmented mask is used to segment the other images by a digital processor. Parameters related to the texture, asymmetry, blotchiness and border irregularities are also automatically estimated. The region of interest is automatically characterized by the digital processor, based on those parameters. The region of interest may include a skin lesion, in which case the present invention enables the characterization of the lesion as malignant or benign.

Abstract: Multiple independent spectral measurements of light reflected from a target are produced concurrently by illuminating the target with a train of laser pulses wherein the train of pulses produces a line spectrum within the illuminating signal. A characteristic dimension of the receiving aperture is established based on illuminating wavelength, a cross-sectional dimension of illuminated region of a target, and the range between a target and the receiving aperture or image plane. The characteristic dimension corresponds to the spacing of peaks in a speckle pattern of an image plane. The use of multiple receiving telescopes having the characteristic dimension allows for independent measurements concurrently by each of the receiving telescopes. The train of illuminating pulses is generated by mode-locked operation of the laser for synchronization of sinusoidal components at line frequencies of the pulse train spectrum, and wherein the spacing of the spectral lines is at least a decorrelation frequency.

Abstract: A method and system for examining biological materials using low-power cw excitation Raman spectroscopy. In accordance with the teachings of the invention, a low-power continuous wave (cw) pump laser beam and a low-power cw Stokes (or anti-Stokes) probe laser beam simultaneously illuminate a biological material and traverse the biological material in collinearity. The pump beam, whose frequency is varied, is used to induce Raman emission from the biological material. The intensity of the probe beam, whose frequency is kept constant, is monitored as it leaves the biological material. When the difference between the pump and probe excitation frequencies is equal to a Raman vibrational mode frequency of the biological material, the weak probe signal becomes amplified by one or more orders of magnitude (typically up to about 10.sup.4 -10.sup.6) due to the Raman emission from the pump beam.

Abstract: A microscope for detecting a portion of the electromagnetic spectrum of a sample image and producing an output signal in response thereto. The output signal may be stored for later reference or an image related to the output signal may be displayed by an image capture and storage system. The microscope may be provided with both an infrared and a visible spectra detector. A rotatable image director having a reflecting surface directs the sample image to an image detector. The microscope may have image detectors such as a CCD camera and a spectrometer. The image detectors of the microscope share a common optical path up to the image director.

Abstract: A method and apparatus for counteracting adverse drug events (ADE's) which are caused by the administration of intravenous medications of incorrect types, concentrations or dosages, and which may result in morbidity and even mortality to recipient patients. A container, preferably in the nature of a transparent plastic bag employed for intravenous administrations, contains the requisite infusion at a prescribed volume, adding a specified amount of prescribed medication possessing a predefined amount of a coloring material, such as a vegetable dye, to the volume of infusion material or liquid in order to form a prescribed concentration of medication, with the coloring material defining a specific type of medication. Analyzing of the concentration of medication is effected through the utilization of spectrophotometric equipment, and to resultingly obtain a real medication concentration value.

Abstract: An imaging spectrometer has fore-optics coupled to a spectral resolving system with an entrance slit extending in a first direction at an imaging location of the fore-optics for receiving the image, a convex diffraction grating for separating the image into a plurality of spectra of predetermined wavelength ranges; a spectrometer array for detecting the spectra; and at least one concave sperical mirror concentric with the diffraction grating for relaying the image from the entrance slit to the diffraction grating and from the diffraction grating to the spectrometer array. In one embodiment, the spectrometer is configured in a lateral mode in which the entrance slit and the spectrometer array are displaced laterally on opposite sides of the diffraction grating in a second direction substantially perpendicular to the first direction. In another embodiment, the spectrometer is combined with a polychromatic imaging camera array disposed adjacent said entrance slit for recording said image.

Abstract: An end-point detector for a plasma etcher, includes a converging lens for receiving strip-like plasma light produced between a pair of opposed electrodes and a spectroscope, having a slit located at a substantial rear-side focal plane of the converging lens, for detecting an etching end time point from a time-based variation of spectrum light intensity of the plasma light which has been converged at the slit and has passed through the slit. The converging lens has a pupil diameter of not greater than ##EQU1## where W is a width of a short side of the strip-like plasma light produced between the electrodes, 1 is a distance between an end of each electrode and a pupil face of the converging lens, NAm is a numerical aperture required by the spectroscope, and h is a width of a short side of the slit of the spectroscope. The converging lens has a numerical aperture of not less than NAm.

Abstract: The present invention includes an apparatus configured for identification of a material, and methods of identifying a material. One embodiment of the invention provides an apparatus including a first region configured to receive a first sample, the first region being configured to output a first spectrum corresponding to the first sample and responsive to exposure of the first sample to radiation; a modulator configured to modulate the first spectrum according to a first frequency; a second region configured to receive a second sample, the second region being configured to output a second spectrum corresponding to the second sample and responsive to exposure of the second sample to the modulated first spectrum; and a detector configured to detect the second spectrum having a second frequency greater than the first frequency.

Abstract: A device uses two laser beams to assist in parking a vehicle having a windshield at a desired distance relative to a surface forward of the vehicle, such as the wall of a garage. Independent adjustment means are preferably provided for angling one or both of the first and second beams so as to converge in a localized region of the surface forward of the vehicle when the vehicle is positioned at a desired distance. The preferred embodiment further includes means for mounting the device to a visor within the vehicle, such that the first and second beams pass through the windshield. A momentary contact button on a bottom panel of the enclosure may then be used to activate the laser by squeezing the device against the visor, if so mounted.

Abstract: The invention uses a resonance Raman spectrometer 1 for achieving the identification and quantitation of analytes including biomolecules, organic and inorganic molecules. According to the present invention, a) a sample 2 is deuterated 3 with D20 for facilitating identification and quantitation of analytes 4 of said sample, b) a monochromatic light 6 illuminates sample 2 of analytes 4 for producing Raman sample light 12 and rejecting Rayleigh light 14, c) the Raman sample light 12 is passed through a depolarizer 19 for producing randomized polarization components 20, d) a Raman sample spectrum 22 is generated, calibrated with respect to an absolute differential Raman cross-section standard in response to said randomized polarization components 22, e) the Raman sample spectrum 22 is provided to a spectral analyzer 24 for identification 26 and/or quantitation 28 of the analytes 4.

Abstract: A system and method for analyzing matter by computer analysis of electrical signals generated by sensing radiation reflected from matter (i.e. tissue, cells, liquid, gaseous or solid particles in a liquid or gas) and/or generated due to fluorescence. In one embodiment, a short pulse of laser radiation is directed at matter also scanned by an electro-optical scanning means to generate image signals. Fluorescent radiation and reflected radiation generating image signals, generate respective variable electrical signals which are computer processed and analyzed to detect and determine the chemical and/or biological composition of the matter. A television camera scans the matter and generates video signals for computer processing and analysis. Simultaneously or sequentially, pulsed laser energy is directed against plural locations of scanned matter, wherein each of such pulses generates a short duration of fluorescent energy in different select portions of the matter under analysis.

Abstract: A capillary spectrometer is disclosed for observing radiation from a source. The spectrometer comprises a capillary array, a dispersive element, and a short wavelength imaging detector. The capillary guide comprises a receiving end and an emitting end. The receiving end is positioned so that it may receive radiation from the source. As radiation travels through the capillary guide, the course of the radiation is changed so that it is emitted in a predetermined path or paths from the emitting end. The emitted radiation falls on the dispersing element which disperses the radiation into a predetermined pattern. The radiation then falls on sensors of the short wavelength imaging detector which generate electrical signals in response to the frequency and intensity of radiation. Insulators may be used to prevent discrete rays of radiation from interfering with each other as they pass from the capillary guide to the short wavelength imaging detector.

Abstract: A co-planar system for determining the shape and dimensions of a surface of an object includes a projector for projecting in a selected plane onto the object a spatially coded pattern of radiation, e.g., light. The system also includes a receiving device capable of imaging the reflected pattern in the selected plane, and a discriminator for determining which portion of the reflected pattern corresponds to which portion of the projected pattern. By this means, a received signal representing less than the complete reflection from the projected pattern can be correlated with a discrete portion of the scanned object. The object is moved relative to the selected plane and the procedure repeated to obtain enough reliable data to generate a reasonably reliable surface profile. The resulting set of received signals and correlations are used to calculate the shape and dimensions of the object.

Abstract: An atomic absorption photometer with a hollow cathode lamp and a deuterium lamp uses for each a power source which receives a variable current and switches it on and off so as to output a constant voltage.

Abstract: In a distance measuring apparatus for measuring the distance to an object on the basis of reflected light obtained as a result of projecting light toward the object, in the case of an active distance measurement operation, the flickering frequency of a light beam projected from a light projection unit (B) toward the object (A) is prolonged within the range in which charges obtained by a signal charge supply unit (C) are not saturated in a circulating shift register (E). When the flickering period is longer than a predetermined period, a distance measurement operation inhibition unit (L) inhibits transition to a passive distance measurement operation.

Abstract: A method for standardizing a spectrometer generating an optical spectrum from a sample, comprising generating at least one optical spectrum from at least one standardization sample each having a chemical composition resulting in the optical spectrum showing a characteristic pattern in a predetermined frequency range, comparing information relating to the pattern(s) to corresponding information relating to at least one reference pattern previously defined as the desired standard response from the at least one standardization sample, determining, based on the comparison, standardizing parameters describing the transition of the pattern(s) of the generated spectrum or spectra to the reference pattern(s) and storing said standardizing parameters in the spectrometer or a computer connected thereto, so that the spectrometer, when presented to an unknown sample, will, using the standardization parameters, generate an optical spectrum substantially identical to that which would be generated in a corresponding spectro