By Dispersed Light Spectroscopy Patents (Class 356/300)
  • Patent number: 10713787
    Abstract: Systems and methods for applying an ensemble of segmentations to microscopy images of a tissue sample to determine if the tissue sample is representative of cancerous tissue. The ensemble of segmentations is applied to a plurality of greyscale or color microscopy images to generate a final image level segmentation and a final blob level segmentation. The final image level segmentation and final blob level segmentation are used to calculate a mean nuclear volume to determine if the tissue sample is representative of cancerous tissue.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: July 14, 2020
    Assignees: University of South Florida, Stereology Resource Center, Inc.
    Inventors: Peter Randolph Mouton, Dmitry Goldgof, Lawrence O. Hall, Baishali Chaudhury
  • Patent number: 10697882
    Abstract: The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: June 30, 2020
    Assignee: IMEC VZW
    Inventors: Veerle Reumers, Dries Braeken, Geert Vanmeerbeeck, Richard Stahl, Andy Lambrechts
  • Patent number: 10687895
    Abstract: A fiber optic probe includes a first diffuse reflectance spectroscopy fiber, a second diffuse reflectance spectroscopy fiber, and a temperature sensor at a distal end of a temperature sensor fiber. Other embodiments further include a treatment fiber for delivering a high optical power density of light to a tumor and a dosimetry fiber for monitoring the light flux of the treatment fiber. Other embodiments utilize an image-guidance step in a method of using the fiber optic probe.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: June 23, 2020
    Assignee: THE UNIVERSITY OF AKRON
    Inventor: Bing Yu
  • Patent number: 10677730
    Abstract: The invention provides improved systems and methods for multiphoton microscopy including pixel clocking techniques for minimizing pixel integration time and providing consistent signal intensity with maximized imaging speeds. Various systems and method are described for optimizing laser repetition rate based on dye lifetime, combining polygonal mirror scanning and stage translation, using the laser pulse signal to time pixel collection, and minimizing laser pulses and dye usage based on signal to background ratios.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: June 9, 2020
    Assignee: APLLIKATE TECHNOLOGIES LLC
    Inventors: Michael Levene, Richard Torres
  • Patent number: 10674919
    Abstract: The use of a transdermal Raman spectrum to measure glucose or other substance concentration can give an inaccurate result if the Raman signals originate at a wrong skin depth. To predict whether a spectrum of Raman signals received transdermally in a confocal detector apparatus and having at least one component expected to have an intensity representing the concentration of glucose or another skin component at a point of origin of the Raman signals below the surface of the skin will accurately represent the concentration, peaks in the spectrum at 883/4 cm?1 and 894 cm?1 are measured to determine whether the Raman signals originate primarily within the stratum corneum so that the spectrum will be less likely to represent the concentration accurately or originate primarily below the stratum corneum so that the spectrum will be more likely to represent the concentration accurately.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: June 9, 2020
    Assignee: RSP SYSTEMS A/S
    Inventor: Stefan Ovesen Banke
  • Patent number: 10677774
    Abstract: A smart phone or tablet includes laser diodes configured to be pulsed and generate near-infrared light between 700-2500 nanometers. Lenses direct the light to a sample. A detection system includes a photodiode array with pixels coupled to CMOS transistors, and is configured to receive light reflected from the sample, to be synchronized to the light from the laser diodes, and to perform a time-of-flight measurement of a time difference between light from the laser diodes and light reflected from the sample. The detection system is configured to convert light received while the laser diodes are off into a first signal, and light received while at least one laser diodes is on, which includes light reflected from the sample, into a second signal. The smart phone or tablet is configured to difference the first signal and the second signal and to generate a two-dimensional or three-dimensional image using the time-of-flight measurement.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: June 9, 2020
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10660526
    Abstract: A remote sensing system includes an array of laser diodes configured to generate light. One or more scanners are configured to receive a portion of the light from the array of laser diodes and to direct the portion of the light from the array of laser diodes to an object. A detection system is configured to receive at least a portion of light reflected from the object and is configured to be synchronized to the at least a portion of the array of laser diodes comprising Bragg reflectors. The remote sensing system is configured to generate a two-dimensional or three-dimensional mapping using at least a portion of a time-of-flight measurement. The remote sensing system is adapted to be mounted on a vehicle and communicate with a cloud. The at least a portion of the two-dimensional or three-dimensional mapping is combined with global positioning system information.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: May 26, 2020
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10653646
    Abstract: The inventive subject matter provides ready-to-administer, preferably anti-oxidant free, epinephrine compositions with improved stability, and methods for preparing the same. Contemplated compositions can be packaged using blow-fill-seal technology or packaged into flexible IV bags and maintain degradation of the epinephrine at a level of less than 5 wt % when stored over at least one months at between 2-40° C.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: May 19, 2020
    Assignee: Nevakar Inc.
    Inventors: Prem Sagar Akasapu, Kumaresh Soppimath, Reema Ajitkumar Puri, Iouri V. Ilitchev, Milan Patel, Pooja H. Tendulkar
  • Patent number: 10634559
    Abstract: A spectrally-scanned hyperspectral EO sensor trades the temporal properties of spectral information content for instantaneous situation awareness by capturing an image frame and scanning the spectral scene (wavelength) to build up spectral content. The objective optical system, preferably including a chromatic aberration enhancing device, separates spectral components of the incident radiation. A focus cell is used to adjust a relative axial focus position of the objective optical system with respect to a detector to at least two different axial focus positions to adjust the image position and read out an image frame for a spectrally-weighted component. A processor computes a relative spatial image contrast from a plurality of image frames at different wavelengths as a function of encoded focus cell position. A mechanism may be configured to move the enhancing device in and out of the optical path to form a dual gray-scale and hyperspectral EO sensor.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: April 28, 2020
    Assignee: Raytheon Company
    Inventor: Casey T. Streuber
  • Patent number: 10627227
    Abstract: The invention relates to an optical device for characterization of a sample (3) comprising —a source (5) of parallel or collimated light, having an emission spectrum that is continuous over an observation wavelength range of at least 50 nm width, for illuminating the sample (3), —a detector (7) of light scattered by the sample (3), operating in said observation wavelength range, —a filter (9) for specific spectral weighting arranged on an optical path upstream of the detector (7) of the scattered light, and —a processing unit (11) for processing the measurement signal in order to extract a characterization parameter of the sample (3).
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: April 21, 2020
    Assignees: Centre National de la Recherche Scientifique, UNIVERSITÉ D'AIX-MARSEILLE
    Inventors: Myriam Zerrad, Michel Lequime, Claude Amra
  • Patent number: 10605729
    Abstract: An ATR-spectrometer has an ATR-crystal which includes a truncated conical section and two planar surfaces that are arranged in parallel to each other, an emitter configured to emit electromagnetic radiation via one of the surfaces to a lateral surface of the truncated conical section configured to reflect the electromagnetic radiation to propagate in the ATR-crystal by a plurality of reflections and to subsequently couple out of the ATR-crystal, and a detector configured to detect the electromagnetic radiation coupled out. The one of the surfaces includes an in-coupling region for coupling in the electromagnetic radiation. The in-coupling region is a projection of a circumferentially extending section of the lateral surface to the one of the surfaces. The emitter has an electromagnetic radiation emitting surface, the projection of which on the in-coupling region exceeds, seen from a center point of the one of the surfaces, an angle (?) of at least 1.5°.
    Type: Grant
    Filed: January 19, 2019
    Date of Patent: March 31, 2020
    Assignee: Spectrolytic GmbH
    Inventor: Benjamin Wiesent
  • Patent number: 10598604
    Abstract: A system for inspecting a surface of a specimen includes a normal incidence phase-shifted deflectometry (PSD) sensor including an imaging sensor, a beam splitter, and an imaging optic arranged between the imaging sensor and the beam splitter. The illumination source illuminates the specimen with a light pattern and is arranged perpendicular to the surface of the specimen. The imaging sensor captures the light pattern reflected from the surface of the specimen in a sensor image. The beam splitter directs a first portion of the light from the illumination source to the optical absorber, a second portion of the light from the illumination source to the surface of the specimen, and the light pattern reflected from the surface of the specimen to the imaging sensor. A data processing apparatus in communication with the normal incidence PSD sensor determines properties of the surface of the specimen based on the sensor image.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: March 24, 2020
    Assignee: Cark Zeiss Industrial Metrology, LLC
    Inventors: Drew Schiltz, Nathaniel Roisen
  • Patent number: 10571395
    Abstract: A universal rapid diagnostics test reader is disclosed and described herein that includes a set of control electronics, a digital camera component, an illumination component, a housing component, and a rapid diagnostics test tray, wherein the tray can hold at least one rapid diagnostics test having a shape and a size in a fixed position relative to the digital camera component and the illumination component, and wherein the reader can accommodate more than one different rapid diagnostics test.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: February 25, 2020
    Assignee: NOWDiagnostics, Inc.
    Inventors: Neven Karlovac, Onur Mudanyali, Sophie Lorraine Gerrick, Ray Carlisle Delcher, Derek Kuochao Tseng
  • Patent number: 10517484
    Abstract: A wearable device includes a measurement device to measure a physiological parameter adapted to be placed on a wrist or an ear of a user. A plurality of semiconductor light sources such as light emitting diodes generate corresponding output light having an initial light intensity. A receiver includes spatially separated detectors receiving reflected light from the output lights and coupled to analog to digital converters. The receiver is configured to synchronize to the semiconductor source(s). The measurement device improves signal-to-noise ratio of the output signal by increasing light intensity relative to the initial light intensity and by increasing a pulse rate. Further improvement in signal-to-noise ratio is achieved by using change detection, where the receiver compares the signals with light on and with light off.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: December 31, 2019
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10512910
    Abstract: Droplet-based methods of analysis. In an exemplary method, a device having a port connected to a chamber may be selected. A sample-containing fluid may be placed into the port. A pressure differential may be created that drives the sample-containing fluid from the port to the chamber and separates the sample-containing fluid into droplets. A two-dimensional monolayer of the droplets may be formed in the chamber. At least a portion of the monolayer may be imaged.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: December 24, 2019
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Billy W. Colston, Jr., Benjamin J. Hindson, Kevin D. Ness, Donald A. Masquelier
  • Patent number: 10502687
    Abstract: Methods and systems are presented for analysing semiconductor materials as they progress along a production line, using photoluminescence images acquired using line-scanning techniques. The photoluminescence images can be analysed to obtain spatially resolved information on one or more properties of said material, such as lateral charge carrier transport, defects and the presence of cracks. In one preferred embodiment the methods and systems are used to obtain series resistance images of silicon photovoltaic cells without making electrical contact with the sample cell.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: December 10, 2019
    Assignee: BT Imaging Pty Ltd
    Inventors: Thorsten Trupke, Juergen Weber
  • Patent number: 10495570
    Abstract: A tunable diode laser absorption spectrometer and a method of processing absorption spectra is used to measure concentrations of selected fuel gas components and calculate several fuel gas parameters, including heating value, relative density, compressibility, theoretical hydrocarbon liquid content and Wobbe index. In the described incarnation, a tunable laser diode directs near-infrared light into an optical cavity through a sample of fuel gas. A sensor measures intensity of light exiting the cavity as the laser wavelength is tuned over a specified range to construct a cavity-enhanced absorption spectrum for the fuel gas. A set of basis spectra for expected component species is used to analyze the spectrum and determine component concentrations, including methane, ethane, carbon dioxide, and other discrete and structured absorbers. Critically, a generic broadband absorption is used to model higher hydrocarbons that present themselves as nearly featureless absorption spectra.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: December 3, 2019
    Assignee: ABB Schweiz AG
    Inventors: Kyle Owen, Manish X. Gupta
  • Patent number: 10478071
    Abstract: A medical imaging method includes imaging a target with a hyperspectral imaging system in order to obtain imaging data. There is provided a method in medical imaging. In the method, a target is imaged with a hyperspectral imaging system in order to obtain imaging data. The obtained imaging data is pre-processed by spatial and spectral averaging. A number of endmembers to be determined from the pre-processed imaging data is selected. The endmembers are extracted from the pre-processed imaging data based on vertex component analysis on the pre-processed imaging data and the selected number of endmembers, said endmembers defining an extremity of projections of the pre-processed imaging data in a subspace spanned by the endmembers. At least one abundance map is generated of the selected number of endmembers in the pre-processed imaging data using a filter vector algorithm on the extracted endmembers and the imaging data.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: November 19, 2019
    Assignee: REVENIO RESEARCH OY
    Inventors: Noora Neittaanmäki-Perttu, Mari Grönroos, Pekka Neittaanmäki, Ilkka Pölönen, Hannu-Heikki Puupponen
  • Patent number: 10460188
    Abstract: A bio-sensing apparatus is used to sense a biopolymer. The bio-sensing apparatus includes a sensing element, a light-transmitting element and a surface plasma resonance layer. The bio-sensing apparatus is disposed on the sensing element. The surface plasma resonance layer is disposed on the light-transmitting element, and is used to receive the biopolymer. The light-transmitting element is disposed between the surface plasma resonance layer and the sensing element.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: October 29, 2019
    Assignee: Gingy Technology Inc.
    Inventors: Jen-Chieh Wu, Chuck Chung, Patrick Lin, Cheng-Jyun Huang, Kuo-Liang You
  • Patent number: 10458908
    Abstract: System and methods may qualify plant material. A system for qualifying plant material may include an inspection zone, a support stage configured to support the plant material in the inspection zone, at least one camera configured to acquire at least one image of the plant material in the inspection zone, at least one processor configured to receive and analyze the camera image to identify a region of interest containing specific plant structures possessing active component, and at least one spectrometer configured to acquire a spectrometric measurement of the plant material in the inspection zone. The at least one processor may be further configured to facilitate a spectrometric measurement of the specific plant structures identified in the camera image, and to enable output of an indicator of a quality measure of the plant material based on the spectrometric measurement of the specific plant structures identified in the camera image.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: October 29, 2019
    Assignee: Gemmacert Ltd.
    Inventors: Dana Yarden, Oded Shoseyov, Merav Blanca
  • Patent number: 10441176
    Abstract: A smart phone or tablet includes a first part having at least one laser diode configured to be pulsed, and a second part having at least one other laser diode, the laser diodes configured to generate near-infrared light, wherein at least some of the laser diodes comprise a distributed Bragg reflector, with some laser diode light directed to tissue including skin. An array of laser diodes generates near-infrared light and includes one or more distributed Bragg reflectors. An assembly in front of the array to forms light spots on the tissue. A first receiver includes detectors that receive light reflected from the tissue. An infrared camera generates data from light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image or mapping using the infrared camera data, and includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: October 15, 2019
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10436653
    Abstract: A method for internal calibration of a detector comprising using one or more hardware processors for the following actions. The method comprises an action of receiving a request for internal calibration of a detector comprising a switchable termination resistor (Dicke switch) and connecting electronically one or more internal calibration circuits to the termination resistor. The method comprises an action of applying two or more input voltage signals to the detector from the calibration circuit and measuring two or more output readings from the detector, each output reading corresponding to one of the input voltage signals. The method comprises an action of computing internal calibration coefficients based on the input voltage signals and the output readings. The method comprises an action of storing the internal calibration coefficients on a non-transitory computer-readable storage medium connected to the hardware processor(s) for subsequent calibration of output values from the detector.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: October 8, 2019
    Assignee: International Business Machines Corporation
    Inventors: Roee Ben-Yishay, Dan Corcos, Danny Elad, Shraga Kraus
  • Patent number: 10419665
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: September 17, 2019
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Xiaoze Ou, Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Patent number: 10401297
    Abstract: Detecting threat materials used in explosives is performed by receiving a sample, and selecting an area of interest on the sample suspected of containing a threat material indicative of an explosive. Detection also includes interrogating the area of interest with a Raman laser producing a Raman spectrum, and comparing an amplitude of a first spectral region in the Raman spectrum to a first predetermined threshold. Detection further includes performing a verification, if the determination indicates that the area of interest includes the threat material, by checking the interrogated area of interest for a secondary indicator of the presence of the threat material, by comparing an amplitude of a second spectral region in the Raman spectrum, which is different from the first spectral region in the Raman spectrum, to a second predetermined threshold, and activating an indicator if the verification indicates that the area of interest contains the threat material.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: September 3, 2019
    Assignee: Battelle Memorial Institute
    Inventors: Andrew P. Bartko, Theodore J. Ronningen
  • Patent number: 10401221
    Abstract: An optical emission spectrometer system includes a light source and a dichroic beam combiner. The light source emits first light in a first direction and second light in a second direction different from the first direction. The dichroic beam combiner receives the first light via a first light path and the second light via a second light path, reflects a portion the first light into an entrance aperture of a light detection and measurement apparatus, and transmits a portion of the second light into the entrance aperture, enabling analysis and measurement of both first and second light characteristics simultaneously. The portion of the first light reflected into the entrance aperture predominately has wavelengths in a first range of wavelengths and the portion of the second light transmitted into the entrance aperture predominately has wavelengths in a second range of wavelengths, different from the first range of wavelengths.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: September 3, 2019
    Assignee: AGILENT TECHNOLOGIES, INC.
    Inventors: Michael Bolles, Yin Sheng Sun, Lindsay Buck, Glyn Russell
  • Patent number: 10386230
    Abstract: A smart phone or tablet includes laser diodes configured to be pulsed and generate near-infrared light between 700-2500 nanometers. Lenses direct the light to a sample. A detection system includes a photodiode array with pixels coupled to CMOS transistors, and is configured to receive light reflected from the sample, to be synchronized to the light from the laser diodes, and to perform a time-of-flight measurement of a time difference between light from the laser diodes and light reflected from the sample. The detection system is configured to convert light received while the laser diodes are off into a first signal, and light received while at least one laser diodes is on, which includes light reflected from the sample, into a second signal. The smart phone or tablet is configured to difference the first signal and the second signal and to generate a two-dimensional or three-dimensional image using the time-of-flight measurement.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: August 20, 2019
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10352769
    Abstract: A method of implementing a self-calibrating database of spectral data includes receiving remotely-sensed spectral data for a geographic location. The method also includes accessing spectral data for a composition of materials at the geographic location from a database of spectral data for compositions of materials at respective geographic locations. The method includes calibrating the spectral data to match the remotely-sensed spectral data and thereby produce calibrated spectral data for the composition. The method includes validating the calibrated spectral data for the composition. And in an instance in which the calibrated spectral data for the composition is validated, the method includes replacing the spectral data with the calibrated spectral data to produce an enhanced database of spectral data for use in identifying materials or compositions of materials therefrom; and in at least one instance, outputting identifiers of the materials in the composition of materials.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: July 16, 2019
    Assignee: The Boeing Company
    Inventor: Robert J Klein
  • Patent number: 10352770
    Abstract: A system for monitoring a chemical reaction in a liquid reactor system includes a sample liquid conduit in communication with the liquid reactor system for receiving sample liquid and directing the sample liquid to an optical spectroscopy device, and a laser beam source. The optical spectroscopy device receives the laser beam from the laser source, and guides the laser beam to the sample liquid to generate an optical spectroscopy signal. A detector detects the optical spectroscopy signal and creates a detection signal responsive to the optical spectroscopy signal. A processor processes the detection signal to determine the identity and amount of at least one chemical species in the liquid. A system for continuously sampling a chemical reaction and a method for continuously monitoring and controlling a chemical reaction are also disclosed.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: July 16, 2019
    Assignee: UT-BATTELLE, LLC
    Inventors: Marissa E. Morales Rodriguez, Joanna McFarlane
  • Patent number: 10337919
    Abstract: A PDA 5 has a plurality of light receiving elements. An A/D converter 30 converts an output signal from each of the light receiving elements of the PDA 5. A conversion processing unit 42 sequentially executes, for the plurality of light receiving elements, a conversion process of converting an output signal from an identical one of the light receiving elements at least twice within a preset time range with the A/D converter 30, to acquire at least two output values. An average value calculation unit 43 calculates an average value of the at least two output values for each of the light receiving elements acquired by the process executed by the conversion processing unit 42.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: July 2, 2019
    Assignee: SHIMADZU CORPORATION
    Inventor: Yugo Ishihara
  • Patent number: 10330927
    Abstract: An optical system images an object region with an optical beam path in an image plane of an image acquisition system. The optical system includes a first optical assembly through which the optical beam path passes and a second optical assembly arranged in the optical beam path on the side of the first optical assembly facing away from the object region. The second optical assembly is a system at least partly compensating longitudinal chromatic aberrations of the first optical assembly occurring in the wavelength range 625 nm???850 nm of the light.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 25, 2019
    Assignee: Carl Zeiss Meditec AG
    Inventors: Artur Hoegele, Thomas Nobis
  • Patent number: 10333646
    Abstract: Optical multiplexers, optical demultiplexers, optical modules including the same, and methods of making and using the same are disclosed. The optical multiplexers include first and second structural blocks and a beam combiner. The first and second structural blocks each include at least one mirror and at least one filter, and are configured to combine a plurality of individual optical signals into a multi-channel optical signal. The beam combiner includes one or more mirrors and one or more filters, and is configured to combine the multi-channel optical signals into a further multi-channel optical output signal having the same number of channels as the multi-channel optical signals. The optical demultiplexers are structurally similar to the optical multiplexers, but provide a complementary or reverse function.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: June 25, 2019
    Assignee: Source Photonics (Chengdu) Co., Ltd.
    Inventors: Chao Tian, Jian Yang, Shengzhong Zhang, Mark Heimbuch
  • Patent number: 10295408
    Abstract: A spectroscopy system (10) for analyzing in-elastic scattered electromagnetic radiation from an object being irradiated by electromagnetic radiation is provided. The system comprises a tunable lens assembly (13) having a tunable lens provided in the beam path between an electromagnetic radiation source (11) and the object (0) and arranged to project a beam of electromagnetic radiation emitted from the electromagnetic radiation source onto an area of the object and receive and collimate the in-elastic scattered electromagnetic radiation from the object. Based on electromagnetic radiation detected by at least a first detector (121) a control unit (14) is capable making a decision to change the operational settings of the tunable lens.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 21, 2019
    Assignee: SERSTECH AB
    Inventors: Katja Szybek, Jan Sonnvik
  • Patent number: 10288557
    Abstract: The instant disclosure provides spectrophotometric methods for assessing histological stains used in a histology analyzer. The methods find use in various assessments including determinations of the identity of a histological stain, determinations of the quality of a histological stain, etc. Also included are devices and systems for practicing the described methods. The instant disclosure also provides computer readable media containing libraries of reference spectrophotometric characteristics of histological stains useful in assessing a histological stain used in a histology analyzer. Also provided is computer readable media containing instructions that cause a computing device to perform steps for making an assessment of a histological stain.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: May 14, 2019
    Assignee: Abbott Laboratories
    Inventors: Svitlana Y. Berezhna, Rene Nieves Alicea, Ema C. Olah
  • Patent number: 10281262
    Abstract: An imaging laser range finder including an objective lens having an optical axis, an object side, and an image side, a controllable pixelated light modulator disposed along the optical axis on the image side of the lens, and a detector disposed optically downstream from the pixelated light modulator on the image side of the lens. The controllable pixelated light modulator is advantageously a MEMS-based system such as a digital mirror device (DMD). An increased field of view may be obtained by incorporating a pair of opposing surface reflectors between an imaging lens and the controllable pixelated light modulator. Associated methods are disclosed.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: May 7, 2019
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventor: Yuzuru Takashima
  • Patent number: 10282649
    Abstract: When the intensity of visible light is properly modulated, the difference between the modulated visible light and the original visible light is not noticeable to human eyes but detectable to electronic devices. Thus, the modulated visible light may be utilized to form patterns that are only recognizable to electronic devices but not to human eyes.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: May 7, 2019
    Assignee: Empire Technology Development, LLC
    Inventor: Zhen Xiao
  • Patent number: 10281327
    Abstract: An apparatus for analyzing light includes an input aperture for receiving light; a first set of one or more lenses configured to relay light from the input aperture; and a prism assembly configured to disperse light from the first set of one or more lenses. The prism assembly includes a plurality of prisms that includes a first prism, a second prism that is distinct from the first prism, and a third prism that is distinct from the first prism and the second prism. The first prism is mechanically coupled with the second prism and the second prism is mechanically coupled with the third prism. The apparatus also includes a second set of one or more lenses configured to focus the dispersed light from the prism assembly; and an array detector configured for converting the light from the second set of one or more lenses to electrical signals.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: May 7, 2019
    Assignee: STRATIO
    Inventors: Jae Hyung Lee, Youngsik Kim, Yeul Na, Juhyung Kang
  • Patent number: 10262413
    Abstract: A soil imaging system having a work layer sensor disposed on an agricultural implement to generate an electromagnetic field through a soil area of interest as the agricultural implement traverses a field. A monitor in communication with the work layer sensor is adapted to generate a work layer image of the soil layer of interest based on the generated electromagnetic field. The work layer sensor may also generate a reference image by generating an electromagnetic field through undisturbed soil. The monitor may compare at least one characteristic of the reference image with at least one characteristic of the work layer image to generate a characterized image of the work layer of interest. The monitor may display operator feedback and may effect operational control of the agricultural implement based on the characterized image.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: April 16, 2019
    Assignee: THE CLIMATE CORPORATION
    Inventors: Michael Strnad, Roger Koch, Dale Koch
  • Patent number: 10258236
    Abstract: A spectrometer includes an illuminating section; a receiving section configured to detect radiation reflected from an object including an optically inhomogeneous scattering medium; a hardware section configured to obtain a solution of an inverse problem to reconstruct an absorption spectrum of the optically inhomogeneous scattering medium, wherein the illuminating section includes at least one light-emitting diode source, a radiation spectral curve of which is divided, by at least two spectral filters having different spectral transmission curves, into at least two spectral regions, to form an equivalent radiation spectrum from at least two spectral sources, and wherein the hardware section applies the solution of the inverse problem based on information about a spectral content of the radiation of the illuminating section, a signal obtained in a form of a response from the optically inhomogeneous scattering medium, and a spectral sensitivity curve of the receiving section.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: April 16, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Alexey Grigor{grave over ( )}evich Anikanov, Sergey Vasil{grave over ( )}evich Afanasyev, Vladislav Vladimirovich Druzhin, Alexander Victorovich Morozov
  • Patent number: 10241042
    Abstract: A wearable device, a charger, and a method for estimating absorbance of the wearable device are provided. The wearable device includes a spectroscope configured to emit a first light to a reference material of a charger, measure an intensity of the first light reflected from the reference material, emit a second light to a skin of a user, and measure an intensity of the second light reflected from the skin of the user; and a processor configured to determine absorbance of the skin of the user based on the intensity of the first light and the intensity of the second light.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: March 26, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Sang Kyu Kim
  • Patent number: 10228399
    Abstract: A smart sensor system can include one or more configurable input and output channels, each configurable channel including one or more switches configured to activate the input and/or output and/or to select a type of input and/or output signal, at least one analog-to-digital converter and at least one digital-to-analog converter operatively connected to the one or more switches for the one or more configurable channels, and at least one controller configured to control the configurable channels.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: March 12, 2019
    Assignee: Simmonds Precision Products, Inc.
    Inventors: Benjamin D. McBride, Peter J. Carini, Matthew B. Burleigh, Travis Gang, Joel Nelson
  • Patent number: 10228330
    Abstract: A gemstone testing apparatus with an apparatus body, a reflector housing with a light reflective layer at its interior surface, a transparent housing portion that is transparent for ultraviolet light, and a detector probe that is protruding from the transparent housing portion. An UV light emitter is provided within the reflector housing, which is adapted for directing the UV light through the transparent housing portion into the vicinity of a tip of the detector probe.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: March 12, 2019
    Assignee: Jubilee Diamond Instrument (S) Pte. Ltd.
    Inventor: Kui Lim Tam
  • Patent number: 10228551
    Abstract: A chromatic confocal measuring device includes a light source, which emits light of a plurality of wavelengths, and a first beam splitter, via which the light from the light source into an imaging optical unit having chromatic aberration on. Light reflected from the measurement object is imaged by the imaging optical unit and the first beam splitter onto a first confocal detection stop arrangement, such that the first confocal detection stop arrangement functions as a confocal aperture. Light incident through the first detection stop arrangement is detected and evaluated by a first detection device. The measuring device has a first slit stop, which functions as a confocal aperture of the measuring device. The measuring device additionally includes a second detection device and a second beam splitter, wherein the second beam splitter splits the light reflected from the measurement object into a first and a second partial beam, which image the same spatial region of the measurement object.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: March 12, 2019
    Assignee: PRECITEC OPTRONIK GMBH
    Inventors: Christoph Dietz, Martin Schönleber, Jean-Francois Pichot
  • Patent number: 10215958
    Abstract: An optical imaging lens is configured to allow imaging rays to pass through a first curved surface of an optical element and the optical imaging lens in sequence. The optical imaging lens includes first, second and last lens element arranged in a sequence. One of the object-side surface and the image-side surface of the last lens element is a second curved surface. A cross-sectional line of the second curved surface of the last lens element obtained by cutting the second curved surface of the last lens element along a plane parallel to the XZ plane is a second curved line. A material of at least one of the first lens element to the last lens element is a plastic material.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: February 26, 2019
    Assignee: Genius Electronic Optical Co., Ltd.
    Inventor: Matthew Bone
  • Patent number: 10213113
    Abstract: A wearable device includes a measurement device adapted to be placed on a wrist or ear having a light source with LEDs to measure physiological parameters. The measurement device generates an optical beam having a near infrared wavelength between 700-2500 nanometers by modulating the LEDs, and lenses to deliver the beam to tissue, which reflects the beam to a receiver having spectral filters in front of spatially separated detectors coupled to analog to digital converters that generate at least two receiver outputs. Signal-to-noise ratio of the beam reflected from the tissue is improved by comparing the receiver outputs, and by increasing light intensity from the LEDs. The receiver is synchronized to the modulation of the LEDs and uses a lock-in technique that detects the modulation frequency. The measurement device generates an output signal representing a non-invasive measurement on blood within the tissue.
    Type: Grant
    Filed: June 24, 2018
    Date of Patent: February 26, 2019
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10208321
    Abstract: A method comprising a series of selective extraction techniques for the parallel production of biodiesel and isolation of several valuable co-products including an alkenone hydrocarbon mixture of the kerosene/jet fuel range (primarily C10-, C12-, and C17-hydrocarbons) and fucoxanthin, a high-valued carotenoid, from the marine alkenone-producing microalgae Isochrysis.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: February 19, 2019
    Assignees: Woods Hole Oceanographic Institution, Western Washington University
    Inventors: Christopher M. Reddy, Gregory W. O'Neil
  • Patent number: 10201283
    Abstract: A smart phone or tablet includes pulsed laser diodes generating light with near-infrared wavelengths between 700-2500 nanometers. First lenses direct light from the laser diodes to tissue. An array of pulsed laser diodes generates light with near-infrared wavelengths between 700-2500 nanometers. Second lenses form light from the array into spots directed on the tissue. An infrared camera synchronized to the laser diodes and the array generates data based on light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image using the data from the infrared camera. The smart phone or tablet includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.
    Type: Grant
    Filed: July 8, 2018
    Date of Patent: February 12, 2019
    Assignee: OMNI MEDSCI, INC.
    Inventor: Mohammed N. Islam
  • Patent number: 10198790
    Abstract: Described in this disclosure is a space-variant Multi-domain Foveated Compressive Sensing (MFCS) system for adaptive imaging with variable resolution in spatial, polarization, and spectral domains simultaneously and with very low latency between multiple adaptable regions of interest (ROIs) across the field of view (FOV). The MFCS system combines space-variant foveated compressive sensing (FCS) imaging covered by a previous disclosure with a unique dual-path high efficiency optical architecture for parallel multi-domain compressive sensing (CS) processing. A single programmable Digital Micromirror Device (DMD) micro-mirror array is used at the input aperture to adaptively define and vary the resolution of multiple variable-sized ROIs across the FOV, encode the light for CS reconstruction, and adaptively divide the input light among multiple optical paths using complementary measurement codes, which can then be reconstructed as desired.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: February 5, 2019
    Assignee: HRL Laboratories, LLC
    Inventors: Yuri Owechko, Daniel Yap, Oleg M. Efimov
  • Patent number: 10194803
    Abstract: A control apparatus includes a data acquiring unit configured to acquire a measured signal obtained by measuring light emitted from a test object onto which light is irradiated, a processing unit configured to calculate an objective function that varies in accordance with a statistical value obtained by statistically processing the measured signal, and a controller configured to control a modulation amount of a wavefront of the light irradiated onto the test object so as to minimize the objective function.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: February 5, 2019
    Assignee: CANON KABUSHIKI KAISHA
    Inventor: Takahiro Masumura
  • Patent number: 10188299
    Abstract: A wearable device for measuring physiological parameters includes a light source having a plurality of semiconductor light emitting diodes (LEDs) each configured to generate an output optical beam, wherein at least a portion of the one or more optical beam wavelengths is a near-infrared wavelength. The light source is configured to increase signal-to-noise ratio by increasing light intensity for at least one of the LEDs and by increasing a pulse rate of at least one of the LEDs. A lens is configured to receive the output optical beam and to deliver a lens output beam to tissue. A detection system generates an output signal in response to the lens output beam reflected from the tissue, wherein the detection system is configured to be synchronized to the light source, and is located a different distance from a first one of the LEDs than a second one of the LEDs.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: January 29, 2019
    Assignee: Omni Medsci, Inc.
    Inventor: Mohammed N. Islam
  • Patent number: 10190866
    Abstract: The embodiments of the present disclosure relate to a Fabry-Perot cavity, a manufacturing method thereof, an interferometer and a measuring method for wavelength of light. The Fabry-Perot cavity includes two parallel substrates and a liquid crystal layer between the two parallel substrates, and a sealed cavity is defined between the two substrates; wherein the two substrates comprise a first substrate and a second substrate, light could enter through the first substrate and run out from the second substrate via the liquid crystal layer, and a deflection angle of the liquid crystal layer could be changed by applying various voltage between the two substrates.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: January 29, 2019
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventor: Zhongxiao Li