Abstract: A method of emitting wavelength-swept light includes controlling either one or both of magnitudes and on/off timings of currents to be applied to a first gain medium of a first optical generator and a second gain medium of a second optical generator to control an intensity and a wavelength region of each of first wavelength-swept light and second wavelength-swept light; generating the first wavelength-swept light having a first center wavelength based on the current applied to the first gain medium of the first optical generator; generating the second wavelength-swept light having a second center wavelength based on the current applied to the second gain medium of the second optical generator; and emitting output wavelength-swept light by coupling the first wavelength-swept light and the second wavelength-swept light.

Abstract: The present invention relates to an apparatus for low coherence optical imaging, and more particularly to an apparatus for low coherence optical imaging which can obtain the information of the different depths of a sample simultaneously. The apparatus comprises a phase transformation unit or a beam shift unit. The phase transformation unit or beam shift unit transforms and reflects the reference light, such that the reflected reference light comprises different phases at the different positions of a cross-section. When the reference light and a information light from the sample are superimposed on a photo detector, the information of the different depths of the sample is obtained. By using the apparatus of the present invention, the elements, the volume, and the cost of the apparatus are reduced. Because of only two-dimensional scanning is required, the scanning rate is improved.

Abstract: An optical coherence tomography apparatus includes a light source, a light coupling module, and an optical path difference generating module. The light source emits a coherent light. The light coupling module divides the coherent light into a first incident light and a second incident light. The first incident light is emitted to an item to be inspected and a first reflected light is generated. The second incident light is emitted to the optical path difference generating module, a second reflected light is generated according to the second incident light by the optical path difference generating module through changing the transparent/reflection properties of at least one optical devices of the optical path difference generating module, so that there is a optical path difference between the first reflected light and the second reflected light.

Abstract: A polarization sensitive spectral interferometer apparatus and method for analyzing a sample by optical energy reflected from the sample. The polarization sensitive spectral interferometer apparatus and method determines polarization properties of the sample by optical energy reflected from the sample.

Abstract: Accordingly, exemplary embodiments of an apparatus probe catheter and method can be provided for irradiating a structure. In particular, an interferometer may forward forwarding an electromagnetic radiation. In addition, a sample arm may receive the electromagnetic radiation, and can include an arrangement which facilitates a production of at least two radiations from the electromagnetic radiation so as to irradiate the structure. Such exemplary arrangement can be configured to delay a first radiation of the at least two radiations with respect to a second radiation of the at least two radiations.

Abstract: In a method and a system for optical coherence tomography, light, with which a specimen (1) is irradiated, is emitted by an interferometer (10), which comprises a beam splitter (13) and a reflector (12). Light reflected by the specimen (1) is collected by a detector (11), and the reflector (12) is brought into a number of positions at different optical distances away from the beam splitter (13). To record images of a specimen (1) easily and quickly, with high quality, the light reflected by the specimen (1) is collected a number of times by the detector (11) and converted into corresponding detector images, while the reflector (12) in the respective position is in the rest position. An averaged detector image is obtained for each position. A tomogram is generated from the averaged detector images obtained for the different positions of the reflector (12).

Abstract: Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls for numerical aperture and focal position of the imaged OCT beam.

Abstract: Preferred embodiments of the present invention are directed to systems for phase measurement such as for imaging small biological objects with light. These embodiments can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. Light based techniques with nanometer resolution enable the cellular machinery to be studied in its native state. Thus, preferred embodiments of the present invention include systems based on principles of interferometry and/or phase measurements and are used to study cellular physiology.

Abstract: A 3D OCT confocal imaging apparatus includes a light source module for providing an illumination beam with wider bandwidth from a crystal fiber; a reference source module; a pickup module; a beam splitter; an optical filter; and a sensor module. When the illumination beam illuminates a sample, a pickup objective lens and a piezoelectric actuator of the pickup module together provide an image beam scanning the sample in depth direction. The image beam and a reference beam from the reference source module together form an interference image beam, which is converted by a photosensor into a coherence image electric signal. Meanwhile, the interference image beam passes through a pinhole to form a confocal image, which is converted by an excited light photometer into a confocal image electric signal. With an image processing system, a 3D OCT confocal microscopic image of the sample can be produced from these image electric signals.

Abstract: An optical coherence tomographic imaging apparatus including a planar image obtaining unit configured to obtain a planar image of a subject based on a return beam from the subject irradiated by the irradiation unit that irradiates the subject with light of a first wavelength band, a tomographic image obtaining unit configured to obtain a tomographic image of the subject based on a beam in which a return beam from the subject irradiated with the laser beam emitted while sweeping a second wavelength range which is longer than the first wavelength band and a reference beam corresponding to the laser beam are combined, and a correction unit configured to correct an optical path length difference generated due to a difference between the first wavelength band and the second wavelength band.

Abstract: An optical coherence tomography imaging apparatus that acquires a tomographic image from interference light between a reference beam and a measuring beam obtained via an object includes a control unit configured to control a difference in optical path length between the reference beam and the measuring beam by a control method according to an imaging target region, and a signal processing unit configured to generate image data of the object based on an electrical signal obtained by detecting the interference light with the difference in optical path length controlled by the control method.

Abstract: There is provided a method of identifying a region of interest in sample. The method comprises obtaining one or more optical coherence tomography (OCT) axial scans at one or more locations over the sample surface; for each axial scan, determining an integrated total of OCT intensity over the depth of the scan, and determining an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached; and determining the from the one or more attenuation depths a region of interest in the sample. Generally, the method does not rely the accuracy (or inaccuracy) of any particular scientific model of scattering and attenuation. It is therefore robust and can be employed across a wide variety of samples, including non-biological ones.

Abstract: The time delay (and therefore the OPD) between object and reference beams in an interferometer is manipulated by changing the spectral properties of the source. The spectral distribution is tuned to produce a modulation peak at a value of OPD equal to the optical distance between the object and reference arms of a Fizeau interferometer, thereby enabling the use of its common-axis configuration to carry out white-light measurements free of coherence noise. Unwanted interferences from other reflections in the optical path are also removed by illuminating the object with appropriate spectral characteristics. OPD scanning is implemented without mechanical means by altering the source spectrum over time so as to shift the peak location by a predetermined scanning step between acquisition frames. The invention and its advantages are applicable to optical coherence tomography as well as conventional white light interferometry.

Abstract: Provided are forward-imaging optical coherence tomography (OCT) systems and probes. In one embodiment, a scanning reflector surface is configured to be rotated about two axes in a single operating plane to direct light transmitted along the sample path to a sample to be imaged.

Abstract: Systems for extended depth frequency domain optical coherence tomography are provided including a detection system configured to sample spectral elements at substantially equal frequency intervals, wherein a spectral width associated with the sampled spectral elements is not greater than one-half of the frequency interval. Related methods are also provided herein.

Abstract: Due to potential sampling errors (due to small tissue samples not necessarily directly from the developing tumor) and limited optical resolution (˜1 micron), cancer may be missed or detected too late for optimal treatment, or conservative interpretation of indeterminate findings could lead to unnecessary surgery. The novel technology herein—Spatial-domain Low-coherence Quantitative Phase Microscopy (SL-QPM)—can detect structural alterations within cell nuclei with nanoscale sensitivity (0.9 nm) (or nuclear nano-morphology) for “nano-pathological diagnosis” of cancer. SL-QPM uses original, unmodified cytology and histology specimens prepared with standard clinical protocols and stains. SL-QPM can easily integrate in existing clinical pathology laboratories. Results quantified the spatial distribution of optical path length or refractive index in individual nuclei with nanoscale sensitivity, which could be applied to studying nuclear nano-morphology as cancer progresses.

Abstract: The invention relates to a system and to a corresponding method for optical coherence tomography having an interferometer (10) for emitting light with which a specimen (1) is irradiated, the interferometer (1) comprising a beam splitter (13) and at least one reflector (12) the optical distance (I) of which from the beam splitter (13) is changeable, a specimen objective by means of which light emitted by the interferometer (10) is focussed in a focus lying within the specimen (1), and a detector (30) for collecting light which is reflected by the specimen (1).

Abstract: The invention discloses an optical interferometer which can be used to provide simultaneous measurements over multiple path lengths and methods to employ such an interferometer as to achieve a variety of functions covering simultaneous measurements at different depths separated by an increment of a multiple differential delay matched in the interferometer as well as imaging. Optical sensors, optical coherence tomography (OCT) set-ups, optical sensing methods and OCT methods are disclosed which can provide: (i) multiple en-face images at several depths with dynamic dispersion compensation, (ii) fast acquisition of cross sections, (iii) fast acquisition of 3D volumes of a scattering object while maintaining dynamic focus; (iv) fast acquisition of long axial measurement profiles, non mechanical, with dynamic focus, range scalable, with applications in tracking and OTDR.

Abstract: The present invention provides a measurement apparatus which measures a surface shape of a measurement target surface, the apparatus including an optical system configured to split light from a light source into measurement light and reference light, guide the measurement light onto the measurement target surface, and guide the reference light onto a reference surface, a detection unit configured to detect an intensity of the measurement light reflected by the measurement target surface, an intensity of the reference light reflected by the reference surface, and an interference pattern formed between the measurement light reflected by the measurement target surface and the reference light reflected by the reference surface, and a processing unit configured to obtain a surface shape of the measurement target surface based on an interference signal of the interference pattern detected by the detection unit.

Abstract: The present invention relates to an optical imaging apparatus and a method, and more particularly to an optical imaging apparatus and a method with short coherence length optical source. The apparatus comprises an optical source with a plurality of outputs for providing a reference light and a sample light; a sample probe module for leading the sample light to a sample, and leading an information light out; an interference module for leading the reference light to a photo detector, and leading the information light to the photo detector; and a signal processing unit electrically coupled to the photo detector; wherein the reference light and the information light are superimposed on the photo detector, an interference light pattern is detected by the photo detector, and a signal that represents the interference light pattern is transmitted to said signal processing unit for analyzing the spatial information of the sample.

Abstract: An optical tomographic image acquisition apparatus comprises a light source unit emitting light; a light dividing device dividing the light from the unit into measurement light and reference light; a projecting device arranged inside a tubular sheath to project the measurement light onto an object; a combining device combining reflected light reflected from the object or the sheath and the reference light; an interference light detecting device detecting interference light between the reflected light and the reference light; an interference signal acquiring device acquiring an interference signal; a tomographic image acquiring device acquiring an optical tomographic image; and a reference position adjustment section detecting a sheath interference signal that is an interference signal of the reflected light reflected from the sheath from the interference signals and adjusts an optical tomographic image reference position as a reference to acquire the optical tomographic image based on the detected sheath inte

Abstract: An optical image measurement device 1 causes an interference light generator to split a low-coherence light into a signal light and a reference light, and superimposes the signal light propagated through a measured object 5000 and the reference light propagated through the reference mirror 9 to generate an interference light. Two-dimensional photosensor arrays 14 and 15 detect the interference light. A computer 16 forms an image of the measured object 5000 based on the detection result. By inserting the optical fiber bundle 5 into the measured object 5000 to perform a measurement, a tomographic image of a deep tissue of the measured object 5000 can be obtained. Furthermore, the optical image measurement device 1 can form a high-resolution image of the deep tissue of the measured object 5000 because performing a measurement using the OCT technology.

Abstract: An optical low-coherence reflectometry with spectral reception for obtaining images without coherent noise caused by self-interference of the radiation scattered from the studied object and by spurious reflections in the optical path of the system is disclosed. Two or more consecutive measurements of the interference spectrum are made. During at least one measurement of the interference spectrum by means of the interference control unit the phase between the interfering parts of the radiation is modulated by a certain law during exposure, which results in averaging and zeroing of the cross-correlation (useful) component of the registered spectrum, and during at least one additional measurement of the interference spectrum, the phase between the interfering parts of the radiation is not modulated during exposure. The phase between the interfering parts of the radiation may be set to be different in additional measurements of the interference spectrum.

Abstract: A method and an apparatus for generating a tomographic image are provided. The method for generating a tomographic image may involve: detecting a principal frequency region corresponding to a portion of a frequency data corresponding to a tomographic image, determining a plurality of sub frequency regions within the principal frequency region, and generating, by a processor, the tomographic image by synthesizing data of the plurality of sub frequency regions.

Abstract: An OCT apparatus includes, in addition to a first light source that changes a wavelength of light that is emitted, a second light source that emits light having a particular wavelength. The OCT apparatus is formed so that, when light having the particular wavelength is emitted from the first light source, the light emitted from the second light source is detected by a second optical detector.

Abstract: An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.

Abstract: A signal generation method for generating an information signal F(b) by performing a Fourier transform on a signal f(a) includes the following steps: detecting the maximum peak intensity of the information signal F(b); calculating an amplitude, a phase, and a frequency of the signal f(a) corresponding to the maximum peak intensity; generating a signal by causing the signal f(a) corresponding to the maximum peak intensity to extend along an ‘a’ axis on the basis of information about the amplitude, the phase, and the frequency of the signal f(a); generating an extrapolation signal by extracting a signal in a region smaller than a1 and a signal in a region larger than a2 from the signal, where a1<a2; generating a composite signal by combining the extrapolation signal with the signal f(a) in a range from a1 to a2; and performing a Fourier transform on the composite signal.

Abstract: An optical coherence tomographic apparatus wherein a reference light path includes at least a first reference light path and a second reference light path having an optical path length shorter than that of the first reference light path, wherein first tomographic information of the object at a first inspection position based on the optical interference using the first reference light path and second tomographic information of the object at a second inspection position based on the optical interference using the second reference light path, are acquired, the second inspection position being shallower than the first inspection position with respect to a depth direction of the object, and wherein a positional deviation a tomographic image at the first inspection position obtained based on the first tomographic information is corrected using the second tomographic information.

Abstract: Methods and devices are disclosed for acquiring depth resolved aberration information using principles of low coherence interferometry and perform coherence gated wavefront sensing (CG-WFS). The wavefront aberrations is collected using spectral domain low coherence interferometry (SD-LCI) or time domain low coherence interferometry (TD-LCI) principles. When using SD-LCI, chromatic aberrations can also be evaluated. Methods and devices are disclosed in using a wavefront corrector to compensate for the aberration information provided by CG-WFS, in a combined imaging system, that can use one or more channels from the class of (i) optical coherence tomography (OCT), (ii) scanning laser ophthalmoscopy, (iii) microscopy, such as confocal or phase microscopy, (iv) multiphoton microscopy, such as harmonic generation and multiphoton absorption. For some implementations, simultaneous and dynamic aberration measurements/correction with the imaging process is achieved.

Abstract: A method for increasing the imaging rate for an optical coherence tomography system is disclosed. The method comprises generating an interferometric signal by interrogating each of M image points on a sample with a plurality of wavelength bands that are collectively spectrally interleaved, time encoding the interferometric signal, and sampling the time-encoded interferometric signal at a single detector.

Abstract: An optical detector system comprises a hermetic optoelectronic package, an optical bench installed within the optoelectronic package, a balanced detector system installed on the optical bench. The balanced detector system includes at least two optical detectors that receive interference signals. An electronic amplifier system installed within the optoelectronic package amplifies an output of at least two optical detectors. Also disclosed is an integrated optical coherence tomography system. Embodiments are provided in which the amplifiers, typically transimpedance amplifiers, are closely integrated with the optical detectors that detect the interference signals from the interferometer. Further embodiments are provided in which the interferometer but also preferably its detectors are integrated together on a common optical bench. Systems that have little or no optical fiber can thus be implemented.

Abstract: A device for the interferometric measurement of a sample, in particular the eye, including an interferometer arrangement with a first measurement beam path, through which a measurement beam falls onto the sample, and a first reference beam path, through which a reference beam runs, which is applied to the measuring beam for interference. The interferometer arrangement includes a second measuring beam path and/or second reference beam path. The optical path lengths of the second measuring beam path and/or second reference beam path are different from one of the first beam paths. The wave length difference is selected according to a distance of two measuring areas which are arranged at a distance in the depth direction of the sample.

Abstract: Phase differences associated with a defocused wavefront can be determined from a single color image. The color image, which is a measurement of intensity as a function of wavelength, is used to calculate the change in intensity with respect to wavelength over the image plane. The change in intensity can then be used to estimate a phase difference associated with the defocused wavefront using two-dimensional fast Fourier transform solvers. The phase difference can be used to infer information about objects in the path of the defocused wavefront. For example, it can be used to determine an object's shape, surface profile, or refractive index profile. It can also be used to calculate path length differences for actuating adaptive optical systems. Compared to other techniques, deriving phase from defocused color images is faster, simpler, and can be implemented using standard color filters.

Abstract: An optical coherence tomography device is disclosed for improved imaging. Reduced levels of speckle in the images generated by the device are obtained by forming a B-scan from a plurality of A-scans, wherein each resolution cell of the B-scan is generated through compounding of a subset of the A-scans and wherein at least some of the subset of A-scans are separated by at least half the diameter of a speckle cell both tangent to and orthogonal to the B-scan at that cell.

Abstract: Frequency domain optical coherence tomography (FD-OCT) systems and methods are provided. Thereby, a first measurement and a second measurement is performed, wherein in the first measurement an object region is illuminated by measuring light having a spectrum with a first spectral width and in the second measurement the object region is illuminated with measuring light having a spectrum with a second spectral width, wherein the first spectral width is at least 10% greater than the second spectral width. Further, during the first measurement intensities of spectral ranges of light having interacted with the object and being superimposed with reference light are detected, wherein a width of these spectral ranges is greater than a corresponding width during the second measurement. Thus, switching an axial field of view of structural information of the object across a depth direction is enabled upon minimizing radiation damage at the object.

Abstract: A coherence grid—interferometer for spatially resolved optic measurement of an object, with a light source, an interferometer, a path length—altering unit, and camera with a detection area. The interferometer cooperates with the light source and camera such that an outgoing beam is split into a measuring beam and a reference beam, the measuring beam is at least partially reflected by the object to the detection area of the camera and overlapped via a beam splitter with the reference beam such that the overlapped beams overlap the photo sensors in a planar fashion, and the optic path length—altering unit changes the optic path length of the measuring and/or reference beams. The path length—altering unit has a path scale and a path detector which detect a changing length of the optic path of the measuring and/or reference beams and the interferogram records are synchronized with the path measurement.

Abstract: The time delay (and therefore the OPD) between object and reference beams in an interferometer is manipulated by changing the spectral properties of the source. The spectral distribution is tuned to produce a modulation peak at a value of OPD equal to the optical distance between the object and reference arms of a Fizeau interferometer, thereby enabling the use of its common-axis configuration to carry out white-light measurements free of coherence noise. Unwanted interferences from other reflections in the optical path are also removed by illuminating the object with appropriate spectral characteristics. OPD scanning is implemented without mechanical means by altering the source spectrum over time so as to shift the peak location by a predetermined scanning step between acquisition frames. Finally, the spectrum is controlled on a pixel-by-pixel basis to create a virtual surface that matches the profile of a particular sample surface.

Abstract: A prism is attached to a refractive index dispersion lens by inclining the incident plane of the prism by a prescribed angle with respect to the end face of the refractive index dispersion lens and filling adhesive therebetween. In this way, the amount of light reflected from the bottom plane of the prism decreases in accordance with the angle of inclination of the incident plane, and the interference signal formed by the reflected light from the bottom plane of the prism, and the reflected light of a reference beam therefore weakens and the image signal decreases. Consequently, distinguishing between the image signal and the image signals produced by reflected light from the measurement subject is facilitated.

Abstract: Light is collected from a sample that is to be imaged, such as tissue or the like, and made to undergo self-interference, e.g., on a detector. An imaging system may include a low coherence light source arranged for illuminating the sample, and an interferometer arranged to receive the light collected from the sample and to pass it to a detector. The interferometer includes a beam divider that directs the radiation collected from the sample along two paths, phase-delaying one beam relative to another and then recombining the beams on a detector. A processor may be coordinated with the phase delay and in some embodiments with spatial scanning or detector array addresses, and operates on the signal from the detector to form a tomographic image of the sample illuminated tissue.

Abstract: An optical coherence tomography method according to the present invention comprising the steps of dividing an object to be measured into a plurality of measurement regions adjacent to one another in a direction of irradiation of a measurement light, and acquiring a measurement image for every measurement region based on a wavelength spectrum of a coherent light and acquiring a tomographic image for every measurement region by removing a mirror image of a tomographic image of an adjacent region being adjacent to the measurement region of the measurement image from the measurement image.

Abstract: A beam diameter varying portion varies a first beam diameter of a measuring beam incident on an optical portion to a second beam diameter larger than the first beam diameter. An adjustment portion adjusts a condensing position of the measuring beam on the optical portion based on intensity information of a return beam from a position of an inspection object with the first beam diameter. The beam diameter is varied from the first to the second beam diameter by the beam diameter varying portion at the position adjusted by the adjustment portion to cause the measuring beam having the second beam diameter to be incident. A condensing position can be adjusted in a relatively short time because the measuring beam small in beam diameter is used, and a combined beam can be acquired with high transverse resolution because the measuring beam large in beam diameter is used.

Abstract: An apparatus and method are provided. In particular, at least one first electro-magnetic radiation may be provided to a sample and at least one second electro-magnetic radiation can be provided to a non-reflective reference. A frequency of the first and/or second radiations varies over time. An interference is detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the second radiation. Alternatively, the first electro-magnetic radiation and/or second electro-magnetic radiation have a spectrum which changes over time. The spectrum may contain multiple frequencies at a particular time. In addition, it is possible to detect the interference signal between the third radiation and the fourth radiation in a first polarization state. Further, it may be preferable to detect a further interference signal between the third and fourth radiations in a second polarization state which is different from the first polarization state.

Abstract: The present invention provides an imaging and measuring apparatus for the surface and the internal interface of an object, which comprises a broadband wave source, a wave-splitting structure, a wave-delaying device, a reflecting component, and a sensor. The broadband wave source transmits a broadband incident wave. The wave-splitting structure splits the broadband incident wave into a first incident beam, a second incident beam, and a third incident beam. The first incident beam is illuminated on an object under test, which reflects a measuring beam. The wave-delaying device receives the second incident beam and reflects a reference beam. The reflecting component receives the third incident beam and reflects a calibration beam. The sensor receives a first interference signal of the measuring beam and the reference beam, and a second interference signal of the reference beam and the calibration beam.

Abstract: Portable optical coherence tomography (OCT) devices including at least one mirror configured to scan at least two directions are provided. The portable OCT devices are configured to provide a portable interface to a sample that can be aligned to the sample without repositioning the sample. Related systems are also provided.

Abstract: A light source device capable of varying a light oscillation wavelength includes a plurality of optical gain media, a dispersing element, and a wavelength selecting element. The optical gain media amplify light, and have gain wavelength bands that partially overlap and different maximum gain wavelengths. The dispersing element is formed of a single element. Each of light beams emitted from the optical gain media is incident on the dispersing element. The dispersing element disperses the light beams emitted from the optical gain media into light beams of different wavelengths. The wavelength selecting element selects a light beam of a predetermined wavelength from the light beams of different wavelengths into which the light beams emitted from the optical gain media are dispersed by the dispersing element. The light source device emits the light beam of the predetermined wavelength selected by the wavelength selecting element.

Abstract: The present invention provides a measurement apparatus which measures a wavefront of light traveling from a member to be measured, the apparatus including a first reference surface, a second reference surface configured to function as a reference surface for the first reference surface, an optical system configured to form a first interference pattern of light traveling from the member to be measured and light traveling from the first reference surface, and a second interference pattern of light traveling from the first reference surface and light traveling from the second reference surface, a detection unit configured to detect the first interference pattern and the second interference pattern, respectively, and a calculation unit configured to calculate a wavefront of light traveling from the member to be measured based on the first interference pattern and the second interference pattern detected by the detection unit.

Abstract: There is a situation in that, although a speckle interference optical system is effective for clarification of a process of deformation of a specimen, resolution is insufficient, and execution of a phase shift method for improving the resolution involves a costly apparatus. A phase shift image for an initial fringe pattern is acquired, and a phase variation between phase information on an initial image and a next image is derived by a phase shift method. After that, a phase shift image for the next image is computed by calculation based on the acquired information.

Abstract: A free-space Michelson Interferometer-based Dual Detection Frequency Domain-Optical Coherency Tomography (DD-FD-OCT) apparatus includes a non-polarizing beam splitter that can be used to misalign sample and reference beam paths to provide a stable ?/2 phase shift between simultaneously detected interfering sample and reference beams to eliminate the mirror image created by Fourier transformation during image reconstruction. A hybrid fiber system Mach Zehnder Interferometer- and free-space Michelson Interferometer-based Dual Detection Frequency Domain-Doppler Optical Coherency Tomography (DD-FD-DOCT) apparatus provides higher power efficiency and thus better sensitivity compared to the free-space DD-FD-OCT. Both DD-FD-OCT systems enable functional imaging with the contrasts of Doppler and that of polarization, in addition to full range images simultaneously.

Abstract: In an optical tomographic imaging apparatus in which a tomographic image is acquired using an interference light between a return beam of a first measuring beam and a first reference beam traveling on a beam path having first beam path length changing unit thereon, an optical interferometer detects movement of the inspection object by using an interference light between a return beam of a second measuring beam from a movement detection position and a second reference beam traveling on a beam path having second beam path length changing unit thereon; and positional misplacement correcting unit changes the beam path length of the first reference beam based on the moving amount detected by the optical interferometer, wherein the beam path lengths of the two reference beams can be changed by a mechanism, thus further reducing deformation of an acquired image in an eye ball depth direction caused by a back and forth motion.

Abstract: A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signal associated with a combination of at least one first electro-magnetic radiation received from the sample and at least one second electro-magnetic radiation received from the reference. At least one particular detector may have a particular electrical integration time, and can receive at least a portion of the signal for a time duration which has a first portion with a first power level greater than a predetermined threshold and a second portion immediately preceding or following the first portion. The second portion may have a second power level that is less than the predetermined threshold, and extends for a time period which may be, e.g., approximately more than 10% of the particular electrical integration time.