With Image Recorder Patents (Class 359/363)
  • Patent number: 10338371
    Abstract: Disclosed is an entirely reflective space telescope featuring a segmented primary objective, simulating a refractive Fresnel lens, providing high optical efficiency over a wide spectral range. Each nonfocusing objective segment is all-reflective, having v-shaped mirrored elements for steering a portion of the incident light beam to a secondary focusing module, where an unobstructed wide angle secondary mirror focuses each segment's beam onto a dedicated mirror segment of an optical path corrector. This corrects path length errors, steers and focuses the beams, equally timed and in phase, to an image sensor. A sparsely segmented objective gives larger apertures. For greater apertures, a sparse primary objective and fully tiled secondary relay objective are combined with fully tiled and sparse optical path correctors. A flotilla of fully tiled segmented telescopes can support either amplitude-phase or intensity interferometry.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: July 2, 2019
    Inventor: Glenn Arthur Morrison
  • Patent number: 10264960
    Abstract: An information processing apparatus includes: an image acquiring unit configured to acquire a plurality of types of images of an eye, including a confocal image and a non-confocal image of the eye; an analyzing unit configured to analyze the confocal image and the non-confocal image; a deciding unit configured to decide, based on analysis results of one of the confocal image and the non-confocal image, whether or not to analyze the other; and a display control unit configured to display analysis results of the confocal image and the non-confocal image on a display unit, in a case of deciding to analyze the other.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: April 23, 2019
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hiroshi Imamura
  • Patent number: 10123688
    Abstract: An information processing apparatus includes: an image acquiring unit configured to acquire a plurality of types of images of an eye, including a confocal image and a non-confocal image of the eye; a deciding unit configured to decide a saving format for saving the confocal image and non-confocal image in a storage region; and a saving unit configured to save at least one of the acquired plurality of types of images in the storage region, based on the decided saving format.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: November 13, 2018
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hiroshi Imamura
  • Patent number: 9917990
    Abstract: An imaging system is provided wherein a positioning stage is translated with respect to an objective lens component and a scan mirror is repositioned while a two-dimensional image is made of a biochemical site on a substrate. In an example embodiment, an imaging system comprises a camera, an objective lens component, a positioning stage, and a scan mirror controllable by a servo system that synchronizes movement of the positioning stage and the tilting of the scan mirror so that the substrate image is maintained stable during imaging of the continuously moving positioning stage.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: March 13, 2018
    Assignee: Complete Genomics, Inc.
    Inventors: Bryan P. Staker, Craig E. Uhrich
  • Patent number: 9880378
    Abstract: A microscope includes: a sample placement part having a placement surface on which to place a sample and a bottom face opposite to the placement surface; an observation lens; and an optical unit for generating sheet light and use of the microscope. The microscope of an embodiment is arranged such that the sheet light enters the sample placement part from the bottom face and passing through the sample placement part to irradiate the sample, and fluorescence from the sample passes through the sample placement part toward the bottom face to be received by the observation lens. The microscope can, with this arrangement, utilize the advantages of a SPIM, and allows observation of a sample which observation is free from a restriction of the size of a sample.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: January 30, 2018
    Assignee: RIKEN
    Inventors: Yuichi Taniguchi, Kazuya Nishimura
  • Patent number: 9832447
    Abstract: In the present invention, the following are provided: a 3D information generating unit (3) for generating 3D information as the data of a group of a plurality of points formed by projecting the values of respective pixels of a moving object in accordance with depth information detected from an image pickup image; an overlooking image generating unit (4) for generating an overlooking image by synthesizing the 3D information of the moving object with a space image of an image pickup target region; and a display control unit (5) for displaying the overlooking image.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: November 28, 2017
    Assignee: AMATEL INC.
    Inventor: Joji Konno
  • Patent number: 9829693
    Abstract: A image acquisition device including a connection section having an opening; an optical-path switching unit that changes an optical path of light entering from the opening; and two image acquisition elements. The optical-path switching unit includes two parallel reflective surfaces disposed with a distance therebetween and is swivelable about a swivel axis such that the reflective surface is insertable into and withdrawable from an incident optical axis. The first image acquisition element is disposed on the incident optical axis at the opposite side of the opening with the optical-path switching unit interposed therebetween. The second image acquisition element is disposed at a position where the second image acquisition element acquires an image of the light that has been deflected by the two reflective surfaces and is tilted about central axes of the two image acquisition elements relative to a straight line extending orthogonally to the central axes.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: November 28, 2017
    Assignee: OLYMPUS CORPORATION
    Inventor: Takayuki Kono
  • Patent number: 9703087
    Abstract: Aspects of the subject technology provide a fluorescence module that is configured to provide a selectable light source for fluorescence microscopy, e.g., through independent paired selection of a light source (emitter) and a corresponding light filter. In some implementations, light source and/or light filter selection is controlled through the independent actuation of light sources and/or light filters on a supporting turret structure.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: July 11, 2017
    Assignee: Echo Laboratories, Inc.
    Inventors: Eugene L. Cho, Derek Fuller, Dorian Raymer, Anthony Beatty, Adam Rusch, Giacomo Strollo
  • Patent number: 9635424
    Abstract: A video service is provided by one or more servers which communicate directly with one more clients over a network. The service may provide digital optical disc data storage formatted video, such as for example a Blu-ray format video, and allows Blu-ray video to be streamed to a client device over the network. The system may utilize direct and fast content delivery of content typically found on a high definition digital optical disc. The content may include a movie as well as featurettes and other content. The video service may also include augmented content and may provide overlay content. In addition to these features, the video streaming service may also provide community content as an overlay to improve a user's viewing experience.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: April 25, 2017
    Assignee: SONY INTERACTIVE ENTERTAINMENT AMERICA LLC
    Inventor: David Perry
  • Patent number: 9632301
    Abstract: An instrument and method for scanning a large microscope specimen uses a light source and at least one lens to focus light from the specimen onto a detector array. The specimen holder is located on a scanning stage and the detector array is dynamically tilted about a scan direction during the scan to maintain focus across the width of the scan strip as the scan proceeds. A degree of tilt varies during the scan as is required to maintain lateral focus relative to the detector array.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: April 25, 2017
    Assignee: Huron Technologies International Inc.
    Inventors: Savvas Damaskinos, Arthur Edward Dixon
  • Patent number: 9632305
    Abstract: An optical device such as a telescope may be connected to a camera through the use of a camera that acts as a lens cap for the optical system. The optical device may have an eyepiece and a housing within which a lens is retained. The adapter may have a cover portion, a housing attachment feature, an eyepiece attachment feature, and one or more camera attachment features. The cover portion may cover an end of the housing, and may have an imaging aperture. The housing attachment feature may be positioned at a periphery of the cover portion, and may attach the cover portion to the housing. The eyepiece attachment feature may be positioned proximate the imaging aperture to attach the cover portion to the eyepiece. The camera attachment features may facilitate attachment of a camera to the cover portion in alignment with the imaging aperture.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: April 25, 2017
    Assignee: Celestron Acquisition, LLC
    Inventors: Ron Peters, Corey Lee, Eric J. Kopit, Joseph R. Garrison, Jr.
  • Patent number: 9628676
    Abstract: An imaging system is provided wherein a positioning stage is translated with respect to an objective lens component and a scan mirror is repositioned while a two-dimensional image is made of a biochemical site on a substrate. In an example embodiment, an imaging system comprises a camera, an objective lens component, a positioning stage, and a scan mirror controllable by a servo system that synchronizes movement of the positioning stage and the tilting of the scan mirror so that the substrate image is maintained stable during imaging of the continuously moving positioning stage.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: April 18, 2017
    Assignee: Complete Genomics, Inc.
    Inventors: Bryan P. Staker, Craig E. Uhrich
  • Patent number: 9532841
    Abstract: Robotic, telerobotic, and/or telesurgical devices, systems, and methods take advantage of robotic structures and data to calculate changes in the focus of an image capture device in response to movement of the image capture device, a robotic end effector, or the like. As the size of an image of an object shown in the display device varies with changes in a separation distance between that object and the image capture device used to capture the image, a scale factor between a movement command input may be changed in response to moving an input device or a corresponding master/slave robotic movement command of the system. This may enhance the perceived correlation between the input commands and the robotic movements as they appear in the image presented to the system operator.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: January 3, 2017
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: John D. Stern, Robert G. Younge, David S. Gere, Gunter D. Niemeyer
  • Patent number: 9438773
    Abstract: A universal adapter system having a video camera mount and a digital camera mount for attaching a video camera and a digital camera to a single port of an optical observation device, such as a standard microscope, that allows for simultaneous video and digital camera imaging. An example digital camera mount includes a C-clamp attachment for attaching a standard, off-the-shelf digital camera and a sleeve attached to the adapter housing that allows use of an extendable zoom lens of the digital camera. The adapter may provide increased capabilities by use of a rotatable portion to allow positioning of the digital camera relative to the optical observation device, a parfocal zoom lens for simultaneous zoom adjustment of video and digital cameras, an auxiliary zoom lens, a fine focus adjustment for adjusting the video image independent of the digital image, a smartphone adapter, a Toric reticule and a light filter.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: September 6, 2016
    Assignee: Transamerican Technologies International
    Inventor: Allen R. Howes
  • Patent number: 9268082
    Abstract: The invention provides an illumination device (1) comprising (a) a waveguide element (20) comprising a first face (21), a second face (22), and a waveguide edge (23), and (b) a LED light source (10), arranged to generate light source light (17), with optional collimating optics (11). The LED light source (10) with optional collimating optics (11) is arranged to couple at least part of the light source light (17) into the waveguide element (20) via the waveguide edge (23) of the waveguide element (20). The first face (21) comprises structures (51) arranged to couple at least part of the light out of the waveguide element (20) via the second face (22) to provide second face light (37). The illumination device (1) further comprises a cavity (80), arranged to allow light to escape from the waveguide element (20) into the cavity (80), and a reflector (81), arranged to reflect at least part of the light in the cavity (80) in a direction away from the second face (22) to provide first face light (47).
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: February 23, 2016
    Assignee: Koninklijke Philips N.V.
    Inventors: Erik Martinus Hubertus Petrus Van Dijk, Erik Boonekamp, Rene Henri Wouter Van Der Wal, Antonius Petrus Marinus Dingemans
  • Patent number: 9176121
    Abstract: A method of identifying the elements of a blood sample including placing an aliquot of blood on a transparent substrate such as a coverslip. The blood is allowed to stand and the cells to settle to form a layer or matrix. Inverted microscopy is used to identify the elements in the sample. Various forms of illumination may be used alone or in multiple combinations. The method improves the accuracy due to homogenous distribution of formed elements in the wet drop or aliquot, simplifies the method, lowers the cost of the test and results in a shortened analytical cycle time.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: November 3, 2015
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: James W. Winkelman, Milenko J. Tanasijevic, David Zahniser
  • Patent number: 9140886
    Abstract: An inverted microscope that allows observation of a specimen from underneath includes an objective lens holding unit that holds an objective lens configured to collect at least observation light from the specimen, a tube lens configured to focus the observation light collected by the objective lens, a branching unit configured to branch an optical path of the observation light from the tube lens, and an observation image switching device that is removably provided in a microscope main body between the objective lens and the tube lens and is configured to switch between wavelengths of an observation image or between magnifications of the observation image.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: September 22, 2015
    Assignee: OLYMPUS CORPORATION
    Inventors: Haruyuki Tsuji, Masayoshi Karasawa
  • Patent number: 9134518
    Abstract: A telescope is disclosed that includes a primary mirror configured to accept at a front surface incoming light from a field of view (FOV) and reflect the incoming light. The telescope also includes a secondary mirror that is coupled to the primary mirror and configured to accept the light reflected by the primary mirror and further reflect the light from the primary mirror. The telescope also includes one or more tertiary mirrors coupled to and disposed behind the primary mirror. Each tertiary mirror is configured to accept a portion of the light reflected by the second mirror. Each tertiary mirror is also configured to reflect the light so as to form an exit pupil and create an image on a flat image surface disposed behind the primary mirror. Each exit pupil does not overlap another exit pupil.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: September 15, 2015
    Assignee: Lockheed Martin Corporation
    Inventors: Zachary A. Granger, Raymond M. Bell
  • Patent number: 9091845
    Abstract: A confocal scanning microscope including: an objective system (second objective lens 23 and objective lens 24) illuminating a sample SA with illumination light; a scanning mechanism 31 scanning the sample SA to obtain an intensity signal; and a scanning optical system 32 provided between the scanning mechanism and the objective system. The scanning optical system composed of, in order from the scanning mechanism side, a first positive lens group G1, a second negative lens group G2, and a third positive lens group G3. The third lens group has two chromatic aberration correction portions each formed by a positive lens and a negative lens or negative lens and positive lens. Glass materials are selected such that one performs chromatization and the other performs achromatization, thereby providing a confocal scanning microscope capable of correcting lateral chromatic aberration generated in the objective system in the specific wavelength region by the scanning optical system.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: July 28, 2015
    Assignee: Nikon Corporation
    Inventors: Fumio Suzuki, Naoshi Aikawa, Kotaro Yamaguchi
  • Publication number: 20150103401
    Abstract: The present invention is a microscope slide apparatus and method of use thereof, wherein the slide has an integrated color calibration array of filter elements, each element having a given dimension, each element also having a known transmission spectrum. The complete filter array is observable in the field of view of a microscope under at least one magnification setting of a microscope. The invention further characterized with a secondary integrated filter array that is completely observable at a second magnification setting.
    Type: Application
    Filed: February 19, 2014
    Publication date: April 16, 2015
    Applicant: Datacolor Holding AG
    Inventors: Tae-Young Park, Hong Wei
  • Publication number: 20150062531
    Abstract: Surgical microscope systems are provided including an optical coherence tomography (OCT) system; an objective lens; oculars for direct viewing of a subject distal to the objective lens; a heads up display module configured to direct an optical image through the oculars to be visible to a user of at least one ocular; and a coupling element connected to the surgical microscope coupling the OCT system, the heads up display module and the objective lens. The coupling element has first and second faces, the first face positioned toward the oculars of the surgical microscope and the second face positioned toward the subject. The coupling element is configured to receive a heads up optical display signal at the first face of the coupling element and reflect the signal in a wavelength band of the heads up display module; and receive a signal on the second face of the coupling element and reflect the signal in a wavelength band of the OCT system.
    Type: Application
    Filed: August 28, 2014
    Publication date: March 5, 2015
    Inventor: Eric L. Buckland
  • Patent number: 8965196
    Abstract: A method and associated system for imaging high density biochemical arrays comprises one or more imaging channels that share a common objective lens and a corresponding one or more time delay integration-type imaging cameras with optical alignment mechanisms that permit independent inter-channel and intra-channel adjustment of each of four degrees: X, Y, rotation and scale. The imaging channels are configured to independently examine different spectra of the image of the biochemical arrays.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: February 24, 2015
    Assignee: Complete Genomics, Inc.
    Inventors: Bryan P. Staker, Craig E. Uhrich
  • Publication number: 20150043061
    Abstract: A dual-configuration microscope is provided. The microscope may be converted into an upright configuration or an inverted configuration. The microscope includes a base having a lower portion and an upper portion, the lower portion configured to support the microscope. The microscope further includes a body having a first portion, a second portion, and an intermediate portion extending between the first and second portions. The intermediate portion of the body is rotatably coupled to the upper portion of the base at a rotational coupling. The rotational coupling defines a rotating axis that extends in a longitudinal direction with respect to the microscope. The microscope further includes an objective disposed proximal to the first portion and a light source disposed proximal to the second portion.
    Type: Application
    Filed: September 23, 2014
    Publication date: February 12, 2015
    Inventors: Eugene L. Cho, Ryan P. Talbot, Gregory J. Gemmen, Eric R. Garcia
  • Publication number: 20150043062
    Abstract: A microscope apparatus includes: a stage; one or more light sources that emit light for exciting a sample on the stage; one or more cube turrets that arrange fluorescent cubes selectively on an observation optical path; shutters arranged on an illumination optical path and configured to switch between irradiation of the sample with the light and blocking of the light; an input unit that receives inputs of operation instructions for the shutters; an operation controller that controls operations of the shutters; and a controller that acquires, from a storage unit, operation conditions of the shutters corresponding to the operation instructions, and outputs instruction signals to the operation controller based on the acquired operation conditions in order to change conditions of the plurality of shutters. One of the shutters, and the other of the shutters or the one or more cube turrets are arranged on a same illumination optical path.
    Type: Application
    Filed: October 23, 2014
    Publication date: February 12, 2015
    Applicant: OLYMPUS CORPORATION
    Inventors: Yasuko ISHII, Shinsuke KANEKI, Masaya ABE, Koji IMAZEKI
  • Publication number: 20140247482
    Abstract: A surgical microscope system includes a camera 9 that is turnable around an optical axis K of the camera 9 to optionally select a photographing orientation. The camera 9 is able to pick up an electronic image of an affected part T in an orientation in which a main doctor sees the affected part T, or in an orientation in which an assistant, who is present at a different position from the main doctor, sees the affected part T, or in any other orientation. The electronic image picked up by the camera 9 in a selected orientation is stereoscopically observable with an electronic image display unit 2.
    Type: Application
    Filed: February 25, 2014
    Publication date: September 4, 2014
    Applicant: MITAKA KOHKI CO., LTD.
    Inventors: Masao DOI, Toshio YAMAZAKI
  • Publication number: 20140211304
    Abstract: A surgical microscope system includes a camera 20. The camera 20 includes CCDs 21 and a focusing mechanism (41, 42, 43). If an image displayed on an electronic image display unit 5 is unclear due to a focusing error, the focusing mechanism is operated to focus the image and make the image clearly visible. Without regard to a focusing operation conducted by a doctor D1 on a surgical microscope 4, an assistant D2 on the electronic image display unit is able to manipulate the focusing mechanism and observe clear images on the electronic image display unit.
    Type: Application
    Filed: January 28, 2014
    Publication date: July 31, 2014
    Applicant: MITAKA KOHKI CO., LTD.
    Inventors: Katsuyuki NAKAMURA, Masao DOI, Katsushige NAKAMURA
  • Patent number: 8786946
    Abstract: The surgical microscope system includes a first binocular microscope and a first display device. The first binocular microscope includes an objective lens, a first right ocular lens which provides a first image based on a light flux transmitted through the objective lens, and a first left ocular lens which provides a second image based on a light flux transmitted through the objective lens. The first display device can be disposed opposite to or in alignment with the first binocular microscope, and includes a first right-eye image display surface for displaying the first image and a first left-eye image display surface for displaying the second image. The first display device can be reversed about a horizontal axis extending in a direction along which the first right-eye image display surface and the first left-eye image display surface are located in alignment.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: July 22, 2014
    Assignee: Mitaka Kohki Co., Ltd.
    Inventor: Katsushige Nakamura
  • Patent number: 8780157
    Abstract: According to one embodiment, there is provided an imaging element array including an imaging element group in which a plurality of imaging elements are aligned, each of the imaging elements including an integrally molded input portion, an output portion, and a reflective portion, collecting light input to the input portion, reflecting the light by the reflective portion near a position where light flux is downsized, and outputting the reflected light from the output portion to form an image at an image point, and an inhibiting portion which is formed around the reflected portion in the imaging element group to inhibit light other than the light reflected by the reflective portion from traveling to the output portion.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: July 15, 2014
    Assignee: Toshiba Tec Kabushiki Kaisha
    Inventor: Takashi Shiraishi
  • Patent number: 8743186
    Abstract: A depth expansion apparatus includes an image-pickup-optical-system and an image-pickup-device (hereinafter, IPS) configured to form and pick up images A and B in different focus positions, and a depth-expanded-image forming section configured to generate, based on the images A and B, a depth-expanded-image that maintains a relation between a distance from an object point to the image-pickup-optical-system and luminance. When an image side NA of the image A is represented as NA?, a resolution determined by the IPS, as R, an optical path interval between image forming surfaces for the images A and B, as d, NA of an image at a near photographing distance among the images A and B, as NAn, and NA of an image at a far photographing distance among the images A and B, as NAf, the IPS satisfy the following conditional expressions (1) and (2): RĂ—NA?/2?d??(1) 0.05?(NAf/NAn)2?0.9??(2).
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: June 3, 2014
    Assignee: Olympus Medical Systems Corp.
    Inventors: Toyoharu Hanzawa, Yoshiharu Takasugi, Makoto Tomioka
  • Patent number: 8735790
    Abstract: A microscope for examining an object includes a laser light source generating pulsed light so as to illuminate the object. A measuring system including a detector is adapted to detect detection light coming from the object and the measuring system generates a measurement signal based on the detection light. The microscope includes a programmable integrated circuit including a control element and at least one of a first delay element and a second delay element. The control element is configured to generate a first control signal adapted to control the detector and the measuring system. The control element is further configured to generate a second control signal adapted to control the laser light source. The first and second delay elements are configured to delay the first and second control signals, respectively.
    Type: Grant
    Filed: November 25, 2010
    Date of Patent: May 27, 2014
    Assignee: Leica Microsystems CMS GmbH
    Inventors: Ludger Schulte, Bernd Widzgowski
  • Patent number: 8709878
    Abstract: A method of packaging imager devices and optics modules is disclosed which includes positioning an imager device and an optics module in each of a plurality of openings in a carrier body, introducing an encapsulant material into each of the openings in the carrier body and cutting the carrier body to singulate the plurality of imager devices and optics modules into individual units, each of which comprise an imager device and an optics module. A device is also disclosed which includes an imager device comprising a plurality of photosensitive elements and an optics module coupled to the imager device, the optics module comprising at least one lens that, when the optics module is coupled to the imager device, is positioned a fixed, non-adjustable distance from the plurality of photosensitive elements.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: April 29, 2014
    Assignee: Micron Technology, Inc.
    Inventors: Todd Bolken, Scott Willmorth, Bradley Bitz
  • Patent number: 8704149
    Abstract: An embodiment of present invention discloses an optoelectronic device package including a first auxiliary energy receiver having a first energy inlet and a side wall for substantially directing energy far away from the first energy inlet; an optical element optically coupled to the first auxiliary energy receiver and having a recess facing the first energy inlet; and an optoelectronic device optically coupled to the optical element and receiving the energy from the first energy inlet.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: April 22, 2014
    Assignee: Epistar Corporation
    Inventors: Min-Hsun Hsieh, Tsung-Xian Lee
  • Patent number: 8699130
    Abstract: Microscope, particularly laser scanning microscope, for optical detection of light radiation excited in a specimen, having a detection beam path for detecting spectral components of the light radiation in a plurality of detection channels, wherein the light radiation arrives at a variable longpass filter or shortpass filter from which reflected and/or transmitted components are reflected back with a parallel offset, and the latter arrive at a detector after at least one back-reflection of this kind.
    Type: Grant
    Filed: March 6, 2010
    Date of Patent: April 15, 2014
    Assignee: Carl Zeiss Microscopy GmbH
    Inventor: Ralf Wolleschensky
  • Patent number: 8699129
    Abstract: A microscope system improves the operability of a user in performing a microscope observation. The microscope system attains the improvement by including: a microscope apparatus including a plurality of drive units; a display unit for displaying an operation screen for operation of the microscope apparatus; a pointing device for inputting by a pointer an operation instruction to the microscope apparatus on the operation screen; and a control unit for switching the drive units depending on the position of the pointer on the operation screen, and controlling the operation of the switched drive units depending on the operation of the pointing device.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: April 15, 2014
    Assignee: Olympus Corporation
    Inventors: Tetsuya Shirota, Yasuko Ishii, Akihiko Yoshikawa, Izumi Sakuma
  • Patent number: 8660421
    Abstract: A method and associated system for imaging high density biochemical arrays comprises one or more imaging channels that share a common objective lens and a corresponding one or more time delay integration-type imaging cameras with optical alignment mechanisms that permit independent inter-channel and intra-channel adjustment of each of four degrees: X, Y, rotation and scale. The imaging channels are configured to independently examine different spectra of the image of the biochemical arrays.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: February 25, 2014
    Assignee: Complete Genomics, Inc.
    Inventors: Bryan P. Staker, Craig E. Uhrich
  • Patent number: 8637799
    Abstract: An imaging apparatus is realized which enables a thin finger vein authentication apparatus having a thickness installable in a portable information device. A light beam emitted from an object passes through a visible light cut-off filter 20 and enters a pre-focus lens array 11. The pre-focus lens array 11 focuses the light beam on an opening of a micro aperture array 15. The light beam passed through the micro aperture array 15 diverges, but it is focused with the post-focus lens array 13 on the light detection device 30. With this structure, a thin imaging apparatus can be obtained with maintained resolution, and a finger authentication apparatus installable in a portable information device can be realized.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: January 28, 2014
    Assignees: Japan Display Inc., Panasonic Liquid Crystal Display Co., Ltd.
    Inventor: Kentaro Oku
  • Publication number: 20130335817
    Abstract: Provided is a multiple light source microscope which is capable of performing not only electron image observation but also fluorescence image observation, fluoroscopic image observation and the like for the same biological tissue sample, and is provided with a plurality of observation-use light sources. Disclosed is this multiple light source microscope configured by: an optical microscope unit for observing fluorescence, provided with a light source unit; and a scanning electron microscope unit, wherein the optical microscope has a Cassegrain mirror with an aspherical reflecting surface, and the Cassegrain mirror is arranged in a lens barrel of the scanning microscope unit so as to be coaxial with an optical axis of an electron beam of the scanning electron microscope unit.
    Type: Application
    Filed: January 5, 2011
    Publication date: December 19, 2013
    Inventors: Shinichiro Isobe, Takaaki Kanemaru, Shin-ichi Takasu
  • Publication number: 20130321906
    Abstract: An imaging system for viewing both flat and angled surfaces of a test element, such as the end faces of both PC and APC optical fibers. A light source provides light to the angled surface, while lensing directs a portion of the original light to the angled surface at a second acute angle. A collector, e.g. photodetector, lenses or human eye, receives the portion of the light reflected from the angled surface and generates an image thereof. An annulus is provided in the optical path for managing the light. The annulus includes a transparent outer ring enabling the portion of the light to pass from the light source to the surface at the second acute angle; a central transparent section enabling light reflected from the angled surface to pass to the collector along the longitudinal optical axis; and a first light-blocking ring between the outer ring and the central section for blocking excess light from the light source and reflected from the end surface.
    Type: Application
    Filed: May 24, 2013
    Publication date: December 5, 2013
    Inventors: Peter KRIOFSKE, Kevin G. CASSADY
  • Publication number: 20130321609
    Abstract: A microscope includes an illumination unit for illuminating a mask at a predetermined non-axial illumination angle, an imaging unit for imaging an aerial image of the mask within a predetermined defocus region, and an imaging field stop, in which as a result of the lateral displacement of the aerial image depending on the position within the defocus region and on the non-axial illumination angle, the opening of the imaging field stop is dimensioned such that the aerial image is either completely encompassed or circumferentially cut within the defocus region. A method for characterizing a mask having a structure includes illuminating the mask at at least one illumination angle using monochromatic illumination radiation such that a diffraction image of the structure is created, recording the diffraction image, establishing the intensities of the maxima of the adjacent orders of diffraction, and establishing an intensity ratio of the intensities.
    Type: Application
    Filed: June 3, 2013
    Publication date: December 5, 2013
    Inventors: Holger Seitz, Thomas Frank, Thomas Trautzsch, Norbert Kerwien
  • Publication number: 20130314775
    Abstract: This microscope apparatus is provided with the following elements: an objective lens; a CCD that constructs an image of a sample S; an illumination intensity change unit for adjusting an intensity of excitation light; an sensitivity adjustment unit for adjusting a detection sensitivity by the CCD; a galvanometer mirror for changing a light focusing position of excitation light at a pupil position of the objective lens; a storage unit that stores, for each observation method, a predetermined intensity, a predetermined detection sensitivity, and the light focusing position; and a control unit that switches the observation method, reads out the intensity, the detection sensitivity, and the light focusing position according to the observation method based on a synchronization signal synchronized with a frame signal for constructing an image, and controls the illumination intensity change unit, the sensitivity adjustment unit, and the galvanometer mirror.
    Type: Application
    Filed: May 23, 2013
    Publication date: November 28, 2013
    Applicant: OLYMPUS CORPORATION
    Inventor: Nobuhiro TAKAMIZAWA
  • Publication number: 20130242382
    Abstract: A microscope system includes a plurality of actuators configured to cause components of a microscope to operate, a plurality of power drivers configured to drive the plurality of actuators, respectively, an actuator controller configured to control the plurality of actuators through the plurality of power drivers, and a control management unit configured to control the actuator controller to designate any one of the plurality of power drivers to output a start signal for allowing the designated power driver to start operation to the designated power driver, and to control the actuator controller to stop outputting of the start signal to the designated power driver and the other power drivers other than the designated power driver until passage of a settling time in which driving of one of the plurality of actuators in response to the operation of the designated power driver is completed and then enabled again.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 19, 2013
    Applicant: OLYMPUS CORPORATION
    Inventor: Toshiya KOMURO
  • Publication number: 20130222895
    Abstract: An automated slide scanning system is described. The system comprises an automated focusing unit that is simple and that provides a fine adjustment of a focusing tube without any backlash. The focusing unit comprises a block that is cut or fabricated in a pattern forming a head to support a focusing tube and at least one elongated and rigid arm projecting perpendicularly from the head. One end of the at least one arm is integrally joined to the head. The focusing unit further comprises an elongated, rigid, lever which is substantially parallel and spaced apart from the at least one arm. The lever is pivotally mounted to a hinge and has a first end that is linked to the head of the focusing unit and a second free end. The focusing unit further includes a drive mechanism with a roller coupled to a motor. The roller is eccentric roller and is in constant contact to the lever's second end.
    Type: Application
    Filed: October 20, 2011
    Publication date: August 29, 2013
    Inventor: William Gelbart
  • Patent number: 8428454
    Abstract: A method and associated system for imaging high density biochemical arrays comprises one or more imaging channels that share a common objective lens and a corresponding one or more time delay integration-type imaging cameras with optical alignment mechanisms that permit independent inter-channel and intra-channel adjustment of each of four degrees: X, Y, rotation and scale. The imaging channels are configured to independently examine different spectra of the image of the biochemical arrays.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: April 23, 2013
    Assignee: Complete Genomics, Inc.
    Inventors: Bryan P. Staker, Craig E. Uhrich
  • Publication number: 20130068967
    Abstract: The invention relates to a method and a microscope for generating a microscopic image, wherein a) the sample is illuminated in each case by the microscope lens using the TIRF method; and b) the sample is illuminated in a structured fashion in different displacement positions of the structure. The sample light of the method according to a) and b) is detected in each case for generating an image of at least once sample region, wherein the sample images generated according to a) and b) are set off against one another, preferably multiplied, and the result is stored for generating a new sample image.
    Type: Application
    Filed: March 30, 2012
    Publication date: March 21, 2013
    Inventors: Ingo Kleppe, Yauheni Novikau
  • Patent number: 8351115
    Abstract: A complex type microscopic device includes a slider unit moving a stage, an optical microscope, a scanning electron microscope with an electron axis intersecting with an optical axis of the optical microscope, an optical measurement/observation unit having a magnification between those of the scanning electron microscope and the optical microscope and co-using an objective lens with the optical microscope, and a control unit controlling the entire device, and a display unit having a display screen. During display of a low-magnification optical microscopic image, the control unit controls the display unit to display, on the image, a representation to designate an area to be observed at a magnification of the optical measurement/observation unit, and to display, on the image, another representation to designate an area to be observed at a magnification of the scanning electron microscope during display of a high-magnification optical microscopic image.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: January 8, 2013
    Assignee: Kabushiki Kaisha TOPCON
    Inventors: Hisashi Isozaki, Fumio Ohtomo, Kazuo Nunokawa
  • Patent number: 8350905
    Abstract: A microscope system has a VS image generation means for generating a virtual slide image of a specimen which is constructed by mutually connecting a plurality of microscope images with a first photomagnification photographed and acquired whenever an objective lens and the specimen are relatively moved in a direction perpendicular to the optical axis and which represents the entire image of the specimen, an object-of-interest set means setting an object of interest with respect to the entire image of the specimen represented by the VS image, and a three-dimensional VS image generation means for generating a three-dimensional VS image which is constructed by connecting the microscope images at different focal positions in accordance with the same focal position and which is constructed from the microscope images with a second photomagnification higher than the first photomagnification and represents the image of the object of interest.
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: January 8, 2013
    Assignee: Olympus Corporation
    Inventor: Tatsuki Yamada
  • Patent number: 8345351
    Abstract: A microscope system which can improve the ease of use and the observation environment when a sample is observed using a microscope formed of a stand and a main body which is removable from the stand. A microscope is formed of a main body and a stand, and the main body is removable from the stand. The main body includes an objective lens, an image optical system, a CCD, a compact monitor and a battery, so that the main body, when removed from the stand, can function independently as a microscope. If the main body is mechanically connected to the stand, the main body and the stand are electrically connected via connectors, and an observation image captured by the CCD is supplied from the main body to the stand via the connectors, and is displayed on a monitor.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: January 1, 2013
    Assignee: Nikon Corporation
    Inventor: Atsushi Takeuchi
  • Patent number: 8289620
    Abstract: A method of imaging light from a specimen in which excitation light passes to the specimen via a scanning system and light emitted by luminescence of the specimen passes in another direction via the scanning system to an image capture device having a sensor having discrete spatially distinct light sensitive regions. The scanning system is operated to scan the whole of an area of interest of the specimen, and the excitation light and/or the image capture device are controlled so that light emitted from the specimen in only incident on the image capture device sensor for a specific time period equal to that required for scanning the whole of the area of interest n time. The scanning system is a confocal system. Apparatus is provided for performing the method to produce a video signal for creating an image in a display device or for processing and analysis by a computer.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: October 16, 2012
    Assignee: PerkinElmer Singapore PTE Ltd.
    Inventors: Fedja Bobanovic, John Phillips, Shab Ladha, Patrick Courtney
  • Patent number: 8284246
    Abstract: A microscope system which is capable of changing observation states by driving various optical members and which includes a history record unit for recording history data related to a microscope operation history, a selection unit for selecting one or more microscope operation items from among a plurality of microscope operation items, and a state reproduction unit for reproducing a microscope state on the basis of a microscope operation item(s) selected by the selection unit and on the basis of a microscope operation history related to history data recorded in the history record unit.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: October 9, 2012
    Assignee: Olympus Corporation
    Inventors: Tetsuya Shirota, Takashi Yoneyama, Yasuko Ishii
  • Patent number: RE44216
    Abstract: An optical imaging system for inspection microscopes with which lithography masks can be checked for defects particularly through emulation of high-aperture scanner systems. The microscope imaging system for emulating high-aperture imaging systems comprises imaging optics, a detector and an evaluating unit, wherein polarizing optical elements are selectively arranged in the illumination beam path for generating different polarization states of the illumination beam and/or in the imaging beam path for selecting different polarization components of the imaging beam, an optical element with a polarization-dependent intensity attenuation function can be introduced into the imaging beam path, images of the mask and/or sample are received by the detector for differently polarized beam components and are conveyed to the evaluating unit for further processing.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: May 14, 2013
    Assignee: Carl Zeiss SMS GmbH
    Inventors: Michael Totzeck, Heiko Feldmann, Toralf Gruner, Karl-Heinz Schuster, Joern Greif-Wuestenbecker, Thomas Scheruebl, Wolfgang Harnisch, Norbert Rosenkranz, Ulrich Matejka