Abstract: A laser microscope comprises a laser light source emitting illumination light; an objective applying the illumination light on a sample; a light path compounding unit compounding a first illumination light path and a second illumination path between the laser light source and the objective; a phase-modulation type spatial light modulator placed on a position on the first illumination path, the position also being optically conjugate with a pupil position of the objective, modulating a phase of the illumination light; and a two-dimensional scanning unit placed on the second illumination light path, scanning the sample in a plane orthogonal to an optical axis of the objective.

Abstract: A microscope stand for holding an optical and/or opto-electronical (e.g. video) observation system is mechanically connected to a microscope base, such as a basis plate, feet or rack or the like. In at least one embodiment, the microscope stand is made in two parts, the first part being provided for holding the observation system, and the second part is substantially positively connected to the first part. This second part includes at least one, preferably shaft-like, cavity, in which at least one electric or electronic component, which is preferably either an electric illumination system for the object to be examined by way of the observation system (in this respect the illumination system forms part of the observation system) and/or of an electronic camera system.

Abstract: A stage assembly, an imaging system that uses the stage assembly, and methods for using the stage assembly in a high content screening system. The stage assembly includes a stage having a top surface and an opposing bottom surface and an opening extending between the top and bottom surfaces to receive a specimen plate. The stage assembly also includes a calibration sample bay formed in the stage. A calibration sample can also be secured within the calibration sample bay.

Abstract: A total internal reflection microscope for epi-fluorescence illumination observations includes an objective through which an object to be observed is illuminated by an excitation illumination light at an angle to an observation axis of the microscope. The angle is adjustable to be within the range suitable for a total internal reflection observation. The microscope also has a source of collimated excitation light. An interferometer is arranged in the optical path of the collimated excitation light and is configured to produce an interference pattern. A focusing lens system focuses the interference pattern produced by the interferometer into the back focal plane of the objective. The objective and the focusing lens system image the interference pattern produced by the interferometer into the conjugated image plane of the objective, thereby producing excitation illumination light that modulated spatially in intensity in a plane orthogonal to the observation axis of the microscope.

Abstract: The present invention provides optical systems and methods for determining a characteristic of a cell, such as cell type, cellular response to a biochemical event, biological state and the like. The methods typically involve using interferometry to observe membrane properties in a cell and then use this information to determine one or more characteristics of a cell. The methods of the invention are useful for applications such as drug screening as well as diagnostic techniques.

Abstract: A projection objective for imaging a pattern provided in an object surface onto an image surface of the projection objective has an object-side imaging subsystem for creating a final intermediate image closest to the image surface from radiation coming from the object surface and an image-side imaging subsystem for directly imaging the final intermediate image onto the image surface. The image-side imaging subsystem includes at least one aspheric primary correcting lens having an aspheric primary correcting surface. The object-side imaging subsystem includes a secondary correcting group having at least one secondary correcting lens having an aspheric secondary correcting surface. Conditions involving maximum incidence angles and subaperture offsets at the correcting surfaces are given which should be observed to obtain sufficient aberration correction at very high image-side numerical apertures NA.

Abstract: A microscope examination apparatus including a light source; an illumination optical system configured to guide light from the light source to a specimen; an objective lens configured to collimate return light from the specimen, the objective lens being provided in such a manner as to be displaceable at least in a direction intersecting an optical axis of the objective lens; an image-forming lens configured to image the return light from the specimen, which is collimated by the objective lens; an optical detector configured to detect the return light imaged by the image-forming lens; a microscope main body including the image-forming lens and the optical detector; and an objective-lens driving mechanism configured to drive the objective lens in a direction correcting image blur due to a displacement of the specimen.

Abstract: The invention relates to an adapter (1) for securing a camera (2) or an optical measuring device onto a telescope (3). The adapter (1) comprises a platform (6) for securing the camera (2) and a cylindrical sleeve (4) for securing onto an eyepiece (16) of the telescope (3), wherein the sleeve (4) is attached by flange onto a base plate (5) extending at right angles to a sleeve axis (7). On the base plate (5) a guide is formed, which is formed by two guiding tracks (9, 10) and runs at right angles to the sleeve axis (7), wherein the platform (6) can be adjusted by said guide. On the platform (6) a mechanical stage (23) is also arranged by means of which the camera (2) can be adjusted in a plane running parallel to the sleeve axis (7).

Abstract: Disclosed is a microscope system (1) for sequential observation of different fluorescent dyes that are accumulated in a tissue located in an object plane (22). An illumination system (70) of the microscope system (1) for illuminating the object plane (22) with illumination radiation has at least two operating states. In one of the at least two operating states, the illumination radiation has a spectrum which includes an excitation band (A1) of a first fluorescent dye and, at the same time, is partly free from an excitation band (A2) of another fluorescent dye. An observation system (2) of the microscope system (1) for providing a first observation optical path (33) for optically imaging the object plane (22) has two different operating states as well.

Abstract: A night vision device includes an objective lens assembly, an image detector assembly, an eyepiece lens assembly and a housing. The objective lens assembly receives low intensity light. The image detector assembly converts the low intensity light into a visible output image. The eyepiece lens assembly provides for viewing the output image from the image detector assembly. The housing receives the objective lens assembly, the image detector assembly, and the eyepiece lens assembly. Additionally, the housing aligns the objective lens assembly with the image detector assembly and the eyepiece lens assembly along an optical axis.

Abstract: An image capturing device with a focusing assembly comprises a case formed by an upper casing and a lower casing; a cover for sealing the lower casing; an lower side of the cover having an opening for capturing images of outside objects; a base installed at a connection between the upper casing and the lower casing; an image sensor installed at a lower side of the base for capturing images through an opening of the front cover; a focus adjusting unit including an object lens, an adjusting wheel, an inner tube and an outer adjusting tube; the outer adjusting tube being located within the lower casing and has a longitudinal retaining groove at an inner side thereof; the inner tube being received in the outer adjusting tube; the inner tube having a helical groove; an outer side of the adjusting wheel having a post for driving the adjusting wheel.

Abstract: A microscope with sub-wavelength resolution with a light source for monochromatic light with a predetermined wavelength, an object carrier for an object to be examined, and an image sensor with an optical structure with a first side and a second side opposite to the first side, the optical structure having a negative refractive index, and a pixel array extending along the second side of the optical structure at a predetermined distance, wherein the first side of the optical structure of the image sensor is arranged at a near-field distance smaller than the wavelength of the monochromatic light to the object carrier.

Abstract: The present application generates an image suitable for collectively observing a whole area or all wavelength components in a viewing field. A confocal microscope apparatus includes a detecting unit being disposed on a collecting location of the collecting optical system, separating incident light into a light from a vicinity of a collecting point on the sample and a light from a peripheral of the vicinity, and detecting each of the lights; and an image generating unit generating an image of the sample by a light signal from the vicinity and a light signal from the peripheral of the vicinity, and setting a ratio of the signal of the light from the vicinity of the collecting point to the signal of the light from the peripheral of the vicinity for each of areas on the image.

Abstract: A focusing apparatus for use with an optical system having a high NA objective lens (20) includes an image forming and capturing means (26) for forming an image in an intermediate image zone (44), and for capturing an image by receiving and refocusing light from a selected focal plane within said intermediate image zone, and a focus adjusting means (28) for adjusting the position of the selected focal plane within the intermediate image zone. The image forming and capturing means (26) includes at least one high NA lens. In use, spherical aberration introduced by the high NA objective lens (20) is reduced.

Abstract: Providing an intermittent photo-taking device capable of correcting a focus drift in the optical axis direction by moving a stage to focus on a plurality focus position of a sample. The intermittent recording device 9 receives setting of a photo-taking timing for the intermittent recording, sets to a driving system 2 a plurality of focus points to take photographs of the sample in each photo-taking timing as relative positions with respect to a predetermined reference position, at each photo-taking timing, obtains a focus position as a reference position by the autofocus movement, varies the relative position between the microscope 1 and the stage 51 to focus on the set photo-taking position of the sample S on the basis of the obtained reference position and the relative positions, makes the photo-taking device 8 take photograph of the sample in each focus position, and captures the taken images.

Abstract: A surgical microscope (1) includes a viewing unit (3) for viewing an object (5) and an image projection module (7) for inputting image data (9) into the viewing unit (3). The image projection module (7, 107, 207, 307) includes a plano-convex lens and a plano-concave lens. The image projection module (7, 107, 207, 307) includes an image display unit (11, 111, 211, 311).

Abstract: This invention comprises a method, a software, and a microscope system for monitoring and controlling information loss. The observation of information that is not present and the comparison of ideal loss to actual loss generates an explanatory component by means of a rule set. The user is instructed by the microscope system in an appropriate manner, for example by means of a display, to undertake actions that remove the defects.

Abstract: An inverted fluorescence microscope is described which irradiates an excitation light onto a sample for observation of a fluorescent image of the sample. The fluorescence microscope includes (a) a transmissive illumination light source, which is arranged above a stage for placing the sample and the transmissive illumination light source is arranged facing a horizontal direction; (b) a tilt mirror, which reflects light from the transmissive illumination source and illuminates the sample on the stage from above; (c) a transmissive illumination optical unit including at least the tilt mirror is disposed so as to move in a direction in which the transmissive illumination optical unit is brought away from the stage from a normal position; and (d) a sample cover for shielding a light from the stage, wherein the sample cover is displaceable so as to expose the stage.

Abstract: The invention is based on a microscope (2), in particular a fluorescence analysis microscope, comprising an illumination carrier (20) and illumination units (22a, 22b) arranged thereon for a reflected-light illumination of a sample region (10). In order to be able to illuminate a sample region (10) uniformly in a simple manner by means of a compact device, it is proposed that at least three illumination units (22a, 22b) for the simultaneous reflected-light illumination of the sample region (10) from different directions are arranged on the illumination carrier (20).

Abstract: A microscope system comprises an objective, an image pickup device, a diameter-variable field stop disposed in a conjugate position with the focal plane of the objective, a magnification modifying device disposed in an optical path between the objective and the image pickup device, for modifying the magnification of the image pickup device and a control unit for controlling in such a way as to maintain a state where a field stop diameter is always larger than a field diameter.

Abstract: A microscope system that shifts a plurality of observation locations that are set upon an observation subject in order onto an optical axis of an objective optical system, and for each of the observation locations, performs photography with an image-capturing device of an observation image of the observation subject a plurality of times as time elapses, includes: a drive unit that drives a stage upon which the observation subject is mounted, and the objective optical system, relative to one another two dimensionally in directions orthogonal to the optical axis; a position detection unit that detects at least one of positions of the stage and the objective optical system; and a correction unit that, based upon position information detected by the position detection unit, performs trimming correction upon a plurality of photographic images that have been photographed at each observation location as time elapses, so that the plurality of photographic images become images of a same observation region that include

Abstract: An observation device observing a sample cultured in a culture vessel includes an illuminating unit including an illumination optical system and illuminating the sample, an image-capturing unit including an imaging sensor and generating an image by capturing an image of the sample illuminated by the illuminating unit, and a wavelength limiting filter being placed on an optical axis of the illumination optical system and between the illuminating unit and the image-capturing unit, and limiting a part of wavelengths of an illumination light from the illumination optical system in accordance with optical absorption properties of an additive contained in a culture medium used for culturing the sample. Accordingly, it is possible to suppress a change of the image resulting from the additive and to enable to generate an appropriate image in an automatic observation.

Abstract: This is a microscope observation system comprising a microscope, a camera unit, a light-amount adjustment unit for controlling adjustment parts included the microscope in order to suppress the amount of reflected light of a specimen image formed on the camera unit, a camera adjustment unit for controlling an adjustment part group of the camera unit in order to adjust image signals photo-electrically converted by the camera unit to a desired state, a light measurement unit for measuring the brightness of the specimen, a display unit for displaying a captured image, a control unit for controlling continuous display speed indicating the continuous display interval of an image continuously displayed on the display unit and at least one of an observation position shifting unit for changing the observation position or observation magnification of the specimen or an observation state detection unit for detecting the observation position or the observation magnification.

Abstract: A microscope apparatus can generate information of a super-resolved image at high speed. For that purpose, the microscope apparatus of the present invention is equipped with an image-forming optical system for forming an intermediate image of light emitted from a specimen, a relay optical system for forming an image of the intermediate image, an illuminating optical system that jointly owns an optical path of the image-forming optical system and illuminates the specimen through the optical path of the image-forming optical system, and a spatial modulator disposed on a formation plane of the intermediate image. In this microscope apparatus, the specimen is subjected to structured illumination by an image of the spatial modulator. Light from the specimen which is modulated by the structured illumination is automatically remodulated in the spatial modulator.

Abstract: A method for adjusting a confocal microscope which includes a microscope unit and a confocal scanner unit of Nipkow disk type, emits a light beam for image measurement on a sample, images a returned fluorescent light of the light beam by a CCD (charge-coupled device) digital camera as a confocal image, and enables observation of the sample by the confocal image, the method includes matching a phase of rotation of the Nipkow disk with a phase of an exposure time of the CCD digital camera.

Abstract: The invention relates to an optical recording and/or reading unit particularly suitable for scanning, preferably, a biological sample (1). Substantially, the unit comprises an optical unit (4) and/or a scanning unit (12) and also comprises a control arrangement (10) and at least one adjustment unit (6, 7, 8; 13, 14) loaded by an operator and comprising at least one adjusting element (7, 14). According to the invention, the movements of said adjusting element (7, 14) are evaluated by the control arrangement (10) and generate at least one feedback signal for the operator in the case when one or several values of a predefined threshold are attained or exceeded.

Abstract: Apparatus for and method of rapid three dimensional scanning and digitizing of an entire microscope sample, or a substantially large portion of a microscope sample, using a tilted sensor synchronized with a positioning stage. The system also provides a method for interpolating tilted image layers into a orthogonal tree dimensional array or into its two dimensional projection as well as a method for composing the volume strips obtained from successive scans of the sample into a single continuous digital image or volume.

Abstract: A zoom lens including a varifocal lens unit having a plurality of movable lens groups, and a prism disposed on an image side of the varifocal lens unit. The prism has an incident plane on which a light flux from the varifocal lens unit enters, and an exit plane from which the light flux is emitted toward an image plane, and is configured such that the incident plane or the exit plane or both planes can be inclined with respect to an optical axis, whereby a field of view is shifted by a predetermined amount by inclining the plane.

Abstract: To provide a microscope device capable of resolving a microscopic pattern beyond optical resolution of the microscope device. A microscope device includes, an image sensor, an enlarging optical system forming a magnified image of at least part of a target of observation on the image sensor, and an image processor applying an edge enhance filter having a differential function to a pictorial image obtained by the image sensor to obtain an edge enhanced pictorial image corresponding to the pictorial image, wherein the enlarging optical system includes a variable magnification optical system forming an image of a linear pattern included in an observation area on a surface of the target of observation, as the image having a width that exceeds a size of each of the pixels forming the image sensor and that is equal to or less than a width of an area handled by the edge enhance filter.

Abstract: Providing a microscope capable of movably adjusting an observation field of a sample without moving the sample. The microscope includes a first objective lens, a second objective lens, a mirror, an angular adjustment mechanism, and a shift mechanism. The first objective lens is disposed to the sample side. The second objective lens forms an intermediate image of the sample together with the first objective lens. The mirror is disposed with a tilt on an optical path between the first objective lens and the second objective lens. The angular adjustment mechanism rotatably adjust the mirror in the tilt direction. The shift mechanism makes a shift adjustment of the second objective lens in an axial direction of a rotation axis of the mirror. With the configuration, the observation field can be moved two-dimensionally by the angular adjustment mechanism.

Abstract: The invention relates to an optical recording and/or reproducing unit which is especially suitable for scanning a preferably biological sample (1). The basic construction comprises an adjusting unit (8, 9, 10), a scanning unit (6), an optical unit (4, 5) and a control system (7). The control system (7) controls the adjusting unit (8, 9, 10) and optionally the optical unit (4, 5) and reads out the scanning unit (6). Data acquired in this manner are additionally processed in the control system (7). The control system (7) is equipped with at least one memory (11, 12) into which correction and/or characteristic values of individual units (4, 5; 6; 8, 9, 10) and/or other data are written. The invention is characterized in that the memory (11, 12) is configured as a user-programmable chip card with integrated processor.

Abstract: A projection and detector device that attaches externally to the photo-port of a conventional widefield microscope. The device includes a light source interface for receiving of illumination from a light source, the illumination defining an illumination path. A pattern mask is located within the illumination path for projecting one or a plurality of objects, structures or patterns onto the object plane of the optical microscope. The pattern mask may be used with structured illumination microscopy (SIM) wherein the device projects a moving striped optical grid pattern or Ronchi Ruling onto the object plane in either fluorescence or reflected brightfield imaging. The pattern mask may also be used with a mechanical or digital diaphragm, or a DLP, in specialized techniques such as Fluorescence Recovery After Photobleaching (FRAP), fluorescence photoactivation and targeted illumination. The device without an inserted pattern mask may also be used in deconvolution microscopy.

Abstract: The wide angle lens system described herein allows projection devices (e.g., rear projection display devices) to be more compact than would otherwise be possible. The lens system includes a wide angle lens stage and a relay lens stage. When operating as a projection device, the relay lens stage projects a distorted intermediate image to the wide angle lens stage, which projects the image for display. The distortion cause by the relay lens stage compensates (i.e., is approximately equal and opposite) for the distortion caused by the wide angle stage. The distortion can be the image shape and/or the focal plane. When operating as a taking device, the wide angle stage provides a distorted image to the relay lens stage, which compensates for the distortion and provide a less distorted, or even non-distorted image, for capture.

Abstract: A microscope image pickup system includes: alight source; an object lens; a display device; a record device; a capture device for performing a preview mode in which an image of the test object obtained by the object lens is repeatedly captured and a plurality of captured images are continuously displayed on the display device, or an image record mode in which the image of the test object is captured and the captured image is recorded on the record device; an illumination light amount control device for controlling the amount of light of the illumination light; and a system control device for controlling an operation of the illumination light amount control device depending on the preview mode or the image record mode performed by the capture device.

Abstract: An image capturing device with a focusing assembly comprises a case formed by an upper casing and a lower casing; a cover for sealing the lower casing; an lower side of the cover having an opening for capturing images of outside objects; a base installed at a connection between the upper casing and the lower casing; an image sensor installed at a lower side of the base for capturing images through an opening of the front cover; a focus adjusting unit including an object lens, an adjusting wheel, an inner tube and an outer adjusting tube; the outer adjusting tube being located within the lower casing and has a longitudinal retaining groove at an inner side thereof; the inner tube being received in the outer adjusting tube; the inner tube having a helical groove; an outer side of the adjusting wheel having a post for driving the adjusting wheel.

Abstract: A microscope lens barrel includes an input port where observation light enters the microscope lens barrel; a plurality of output ports which the observation light goes out of the microscope lens barrel; an optical-path switching mechanism which selectively switches an optical path of the observation light to guide the observation light from the input port to at least one of the output ports; and a supporting part which supports the optical-path switching mechanism. The input port, the output ports, and the supporting part are integrally formed as a tubular body frame so that the input port, the output ports, and the supporting part are arranged at respective center positions of sidewalls of the tubular body frame.

Abstract: An optical arrangement having an optical assembly (1) for generating an intermediate image (2) in a beam path is configured and further developed such that an optical element (3) having a plurality of optical waveguides (4) is arranged in the beam bath after the intermediate image (2) to enable the imaging of the intermediate image (2) in a plane on a zone-by-zone or point-by-point basis. Further, a microscope exhibiting such an optical arrangement is specified.

Abstract: A telescope adapter for supporting a camera includes a light beam splitter for receiving light from the telescope and dividing that light into a monitoring bundle of light rays and a recording bundle of light rays, the two bundles of light rays being at angle to each other. The user is permitted to view the monitoring bundle of light rays, and the adapter can support a camera in a position to receive the recording bundle of light rays, so that the user and the camera can receive light from the telescope simultaneously. A first lens system is located between the telescope and the light beam splitter, the first lens system having a total negative power. A monitoring lens system receives and transmits the monitoring bundle of light rays leaving the light beam splitter, and a recording lens system receives and transmits the recording bundle of light rays leaving the beam slitter, both the monitoring and recording lens systems having total positive power.

Abstract: The present invention relates to a microscopic image capturing apparatus having a structure that, in scanning an imageable area of an imaging unit in a predetermined direction in an imaging object area, in which a sample is present, can reliably set a focal point of the imaging unit on each imaging position set inside the imaging object area regardless of the type of focusing actuator. The microscopic image capturing apparatus has a sample setting stage having a sample setting surface that is inclined with respect to a scan plane orthogonal to an optical axis of an objective lens. By moving the sample setting stage, which has such a sample setting surface, along the scan plane in a manner such that the distance in the optical axis direction between the imaging unit and the sample setting surface varies monotonously, the focal point position of the imaging unit is adjusted in only one direction along the optical axis of the objective lens.

Abstract: The invention relates to an optical image converter system to be used in video cameras. The image converter system comprises a recording lens that is to be oriented towards an object and generates a real intermediate image of the object with a defined image size and depth of focus on a first translucent projection disk defining a first image plane. The inventive image converter system further comprises a prism arrangement that is positioned in the beam path as well as an image converter lens which is disposed behind the recording lens in the beam path, is oriented towards the rear face of the projection disk, and is used for generating a real main image of the object on a second image plane. In order to design the image converter system in a compact manner, the projection disk is placed in an intermediate space between two facing, parallel prism surfaces within the prism arrangement.

Abstract: A digital optical microscope includes a primary image sensor that generates a primary image of a sample at a primary frame rate, an auxiliary image sensor that generates an auxiliary image of the sample at an auxiliary frame rate that is faster than the primary frame rate, and a controller that adjusts a focal distance between an objective lens and the sample along an optical axis in response to the auxiliary image, thereby autofocusing the primary image on the sample. The primary image sensor generates the primary image in response to the autofocusing.

Abstract: A microscope digital image acquiring system 1 includes a microscope 2 composed of a microscope unit 10 forming an enlarged image of an object O and a microscope controller 20 controlling movement of the microscope unit 10, an imaging instrument 3 composed of a camera head unit 30 that is attached to the microscope 2 and has an imaging device detecting the enlarged image of the object O and a camera controller 40 that receives a detected signal output from the imaging device and outputs image information of the object O. The microscope controller 20 and the camera controller 40 operate cooperatively in response to control commands sent externally. The system 1 has a connecting cable 52 connecting with both instruments 20 and 40 to carry out communication with each other. Both instruments 20 and 40 operate cooperatively by communicating control commands with each other through the connecting cable 52.

Abstract: A camera hand piece (1) with camera housing (12) has a microscopic probe (2) at the front end. On the rear side is a transmission cable (13) which is attached to the camera hand piece (1) with the aid of a coupling nut (14). The camera housing (12) accommodates a microscope housing (11) and includes a motorized drive (4), which drives an eccentric (7) via a gear (6) mounted in a gear housing (9). Said eccentric (7) actuates a pusher (5), which moves a connecting rod (8) and thereby displaces a focusing lens system (3) attached to it in the axial direction. This axially displaceable focusing lens system (3) together with a condenser lens system (10), forms a microscopic lens system arranged in a microscope housing (11).

Abstract: An image pickup device 1A is constructed with a photodetecting section 10 having a plurality of pixels; a charge transfer section 12 having 16 segmental charge transfer sections T01 to T16; an A/D converting section 15 that converts signals from the charge transfer section 12 to digital data signals; and a digital signal processing section 20. The digital signal processing section 20 carries out, to a correction target of a data signal outputted first in a signal array from the segmental charge transfer section, a data correction by use of a plurality of correcting data signals including at least one of a first correcting data signal included in the signal array and a second correcting data signal included in another signal array from a segmental charge transfer section adjacent to an output end side of the segmental charge transfer section.

Abstract: An automatic microscope is disclosed which incorporates dynamic scanning of the microscope slide and other interchangeable optical path components.

Abstract: The invention relates to a photosensor-chip, a laser-microscope comprising a photosensor-chip and to a method for reading a photosensor-chip. Said photosensor-chip comprises a light-sensitive area and a light-insensitive area. The light-insensitive area has a surface which is at least the double the surface of the light-sensitive area.

Abstract: A focused multi-planar image acquisition in real time, even while a test object is moving is achieved with a system and a method for a focused multi-planar image acquisition in a prober. When a surface of a test object is positioned laterally in relation to tips of separated probe needles, a microscope is focused on the surface of the test object at a first time and on a plane of the probe needles at a second time. The objective lens is provided with a microscope objective lens focusing system, which can focus the objective lens, independently of a vertical adjustment drive of the microscope, on the surface of the test object in a first focal plane and in a second focal plane, which is on a level with the probe needle tips.

Abstract: The disclosure relates to an arrangement in an imaging system for microtitre wells, the arrangement comprising a sample plate having a plurality of wells for samples, and a lens system arranged in connection with the sample plate and comprising an objective and at least one lens group for imaging the rays representing the structure of the samples and passing through the objective to an image detector. In order for the arrangement to enable a rapid imaging of the samples in the wells with a high resolving power, the lens system comprises a plurality of objectives focused to infinity for collecting rays representing the samples, the objectives being at least partly arranged detachably inside wells in the sample plate. The disclosure also relates to a method of imaging samples in microtitre wells.

Abstract: The invention provides an examination apparatus that is capable of observing a specimen in a stationary state while suppressing blurring caused by a control delay. The examination apparatus includes a first optical system and a second optical system for imaging light produced in a specimen, a first image-acquisition unit provided with a plurality of first image-acquisition devices for detecting an image formed by the first optical system, a second image-acquisition unit provided with a second image-acquisition device for acquiring an image formed by the second optical system, and a driving unit configured to cause the images to be formed at substantially the same position in the second image-acquisition unit based on a detection signal of the first image-acquisition unit.

Abstract: A night viewer (10) is adaptable to generate an enhanced image suitable for viewing through an optical scope (16). An input end (18) of the viewer (10) receives the image to be enhanced through an objective lens (20). An image enhancing unit (22) enhances the image. The enhanced image is optically transmitted from a display (28) to the ocular lens (24) of the scope (16). The display (28) is operably connected with the image enhancing unit (22) to display the enhanced image. A Risley prism (30) located in an image path (32) is used to controllably adjust and to maintain boresight alignment (36).