Spacing Of Optical Elements Axially Adjustable Patents (Class 359/379)
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Patent number: 11255798Abstract: A method for detecting lens cleanliness of a lens in a flat-field optical path, the flat-field optical path includes a light source, the lens, a camera, the light source is a narrow-band multispectral uniform surface light source, the camera's light-sensitive surface is disposed perpendicular to an optical axis of the lens and in the light position of the lens, the method including disposing the camera such that the camera's light-sensitive surface is located a distance from the focal plane of the lens and measuring the bright-field image data and the dark-field image data; for each pixel, performing an out-of-focus differential flat field correction to yield a plurality of DiDj out-of-focus differentials; repeating the disposing and performing steps by altering the distance at least two more times; and displaying the out-of-focus differentials in the form of a plurality of images to show uniformity of each of the plurality of images.Type: GrantFiled: September 24, 2021Date of Patent: February 22, 2022Assignee: MLOptic Corp.Inventors: Jiang He, Teresa Zhang, Wei Zhou, Bin Zhang
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Patent number: 11073685Abstract: The invention relates to a microscope (1), in particular an ophthalmic surgical microscope having a vitreoretinal viewing system (6), an optics carrier (14) and a support (2). The invention also relates to a method and a motion controller controlling the movement of the vitreoretinal viewing system (6). The optics carrier (14) is attached movably to the support (2). The vitreoretinal viewing system (6) in turn is attached movably to the optics carrier (14). The vitreoretinal viewing system (6) comprises a front piece (30), such as a optics carrier (14). To avoid contact of the front piece (30) with an eye (16) while the optics carrier (14) is moved for focusing a microscope lens (18), the position of the front piece (30) is automatically maintained stationary with respect to the support (2). This is obtained by controlling the vitreoretinal viewing system (6) to perform a counter movement to the movement of the optics carrier (14).Type: GrantFiled: March 9, 2018Date of Patent: July 27, 2021Assignee: Leica Microsystems K.K.Inventor: Masatoshi Honda
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Patent number: 11035796Abstract: The present disclosure provides Raman spectrum detection apparatus and method. The Raman spectrum detection apparatus includes: a laser configured for emitting excited light; an optics assembly configured to guide the excited light along a first light path to a sample to be detected and to collect a light signal from the sample along a second light path; and a spectrometer configured to process the light signal collected by the optics assembly so as to generate a Raman spectrum of the detected sample. The optics assembly includes a first optical element configured to move, during irradiation of the excited light onto the sample, so as to change a position of a light spot of the excited light on the sample.Type: GrantFiled: December 19, 2018Date of Patent: June 15, 2021Assignee: NUCTECH COMPANY LIMITEDInventors: Haihui Liu, Hongqiu Wang, Jianhong Zhang
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Patent number: 10867184Abstract: A method for training a convolutional neural network for classification of actions performed by subjects in a video is realized by (a) for each frame of the video, for each key point of the subject, generating a heat map of the key point representing a position estimation of the key point within the frame; (b) colorizing each heat map as a function of the relative time of the corresponding frame in the video; (c) for each key point, aggregating all the colorized heat maps of the key point into at least one image representing the evolution of the position estimation of the key point during the video; and training the convolutional neural network using as input the sets associated to each training video of images representing the evolution of the position estimation of each key point during the video.Type: GrantFiled: March 20, 2019Date of Patent: December 15, 2020Inventors: Vasileios Choutas, Philippe Weinzaepfel, Jérôme Revaud, Cordelia Schmid
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Patent number: 10620420Abstract: Embodiments include a spectral reflectance system comprising a detector and a light source coupled to a support member. The system includes a turret coupled to the support member. The turret is configured to receive objective lenses and configured to selectively position each lens in an imaging position relative to a sample to be imaged. A first objective lens is configured to image the sample at the detector when placed in the imaging position. A second objective lens includes an optical director that is configured to form an optical path with an auxiliary detector and image the sample at the auxiliary detector when the second objective lens is in the imaging position.Type: GrantFiled: September 23, 2016Date of Patent: April 14, 2020Assignee: FILMETRICS, INC.Inventor: Scott A. Chalmers
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Patent number: 10606053Abstract: A testing device for body fluid analysis includes: a sheet unit having a sheet of which a first surface receives body fluid of a user to be deposited thereon; a contact unit having a magnifying lens group for magnifying the body fluid deposited on the sheet, the contact unit being provided with a first side at which the magnifying lens group is placed to face the first surface of the sheet and being provided with a second side at which a guide adhering to a photographing means obtaining an image of the body fluid magnified by the magnifying lens group or coming into contact with around an eye of the user is placed; and a light source unit placed to face a second surface of the sheet of the sheet unit in a direction facing the contact unit with the sheet unit in between.Type: GrantFiled: November 22, 2016Date of Patent: March 31, 2020Assignee: JONGROMEDICAL CO., LTD.Inventor: Ji Hoon Kim
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Patent number: 10598913Abstract: The invention relates to a transmitted light illumination apparatus (2) for a microscope (1), said transmitted light illumination apparatus (2) comprising, a planar light source (20), a mirror (23) having a concave mirror surface (24) arranged in the direction of light emitted from the planar light source (20), and at least one diaphragm element (22) being at least partially opaque and being arranged between the planar light source (20) and the concave mirror surface (24) such that by moving the at least one diaphragm element (22) in at least one direction parallel to a plane defined by the planar light source (20), the planar light source (20) is at least partially covered by the at least one diaphragm element (22).Type: GrantFiled: February 7, 2018Date of Patent: March 24, 2020Assignee: Leica Instruments (Singapore) Pte. Ltd.Inventors: Harald Schnitzler, Robert Paulus
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Patent number: 10495863Abstract: The present invention discloses a portable microscope device which can be installed on the smartphone capable of capturing image. By combing these devices, users can observe the detection sample and capture the image of the sample instantly without environment limitation. Moreover, during operation, the user can observe the whole image of the sample by substituting the microscope lens of different magnification ratio or by shifting the position of the sample.Type: GrantFiled: July 7, 2015Date of Patent: December 3, 2019Assignee: AIDMICS BIOTECHNOLOGY CO., LTD.Inventors: Shu-Sheng Lin, Cheng-Ming Lin, Chang-Yu Chen, Tsun-Chao Chiang
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Patent number: 10302930Abstract: An optical apparatus including: a stage on which an object is mounted; an observation section including an imaging system forming an image of the object; a shaft rotatable in a first direction and a second direction opposite to the first direction; a drive that moves the observation section or the stage in a third direction defying a gravity according to rotation of the shaft in the first direction and in a fourth direction opposite to the third direction according to rotation of the shaft in the second direction; and a torque controller including a clutch that permits rotation of the shaft in the first direction, inhibits rotation of the shaft in the second direction, and rotates in the second direction with the shaft as a rotation force in the second direction is input to the shaft, and a restriction section restricting rotation of the clutch.Type: GrantFiled: November 5, 2015Date of Patent: May 28, 2019Assignee: MITUTOYO CORPORATIONInventor: Nobuyoshi Fujii
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Patent number: 10281697Abstract: The invention relates to a system for spherically correcting imaging of a three-dimensional object, comprising a microscope comprising an immersion medium and an embedding medium for holding the three-dimensional object separated from the immersion medium of the microscope by a boundary surface or a cover slip. According to the invention, the thickness (?s) of the immersion medium and the position (?s?) of the primary intermediate image of the three-dimensional object can be variably modified.Type: GrantFiled: March 2, 2016Date of Patent: May 7, 2019Assignee: Carl Zeiss Microscopy GMBHInventor: Rolf Wartmann
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Patent number: 10070847Abstract: An ovulation tester contains: a first body and a second body. The first body is cylindrical and includes a first connecting portion, a first holding disc, and a switch. The switch has a first coupling section which corresponds to a second coupling section of the first body, between the switch and the first holding disc are defined a power supply assembly and a light-emitting element below the power supply assembly, and between the light-emitting element and the first holding disc is defined a light diffuser. The second body is cylindrical and is connected with the first body, the second body includes a second connecting portion for corresponding to the first connecting portion of the first body, a second holding disc for corresponding to the first connecting portion of the first body, and at least one lens in the inner wall thereof below the second holding disc.Type: GrantFiled: January 8, 2016Date of Patent: September 11, 2018Inventors: Chien-Hsiung Hung, Cherng-Jye Jeng
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Patent number: 9706906Abstract: Provided is a small endoscope objective optical system that allows stereoscopic viewing even though a wide angle is used, that reduces the F-number, and that also reduces vignetting. Provided is an endoscope objective optical system that consists of, sequentially from the object side, a negative first lens group, a positive second lens group, and a pair of third lens groups that are disposed side-by-side in the direction of parallax and that form two optical images with parallax, wherein aperture stops are individually provided in the third lens groups, and conditional expression M below is satisfied: Fob_n/Fob_p>?0.5 ??(1), where Fob_n is a focal length of the first lens group, and Fob_p is a focal length of the second lens group.Type: GrantFiled: August 2, 2016Date of Patent: July 18, 2017Assignee: OLYMPUS CORPORATIONInventors: Yasushi Namii, Ikutoshi Fukushima
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Patent number: 9658426Abstract: The invention relates to an objective lens mount (39) with specimen protection and crush protection for objective lenses (4) on a microscope, consisting of an outer objective lens collar (1) having a unit (15) for mounting on an interface of the microscope, preferably on a microscope stand, and a safety element (22) arranged spring mounted and axially movable in the objective lens collar (1), which safety element contains the objective lens (4). According to the invention, in order to maintain a definable stand-off distance between the front lens (5) of the objective lens (4) and the safety element (22) in the objective lens mount (39), a sensor (6) is provided, coupled to a control unit.Type: GrantFiled: April 17, 2014Date of Patent: May 23, 2017Assignee: CARL ZEISS MICROSCOPY GMBHInventors: Ingo Fahlbusch, Georg Herbst, Johannes Knoblich
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Patent number: 9512460Abstract: The present invention relates to a method of studying a sample using an optical microscope, comprising providing the sample in a sample holder with means to maintain the sample at a temperature below 273 K; providing a microscope objective lens, in a thermally insulating jacket, having an extremal lens element proximal to the sample holder; bringing the lens into a focus position proximal to the sample, which separates the extremal lens element and sample by an intervening space, providing a transparent window in said intervening space, with a gap between the window and the extremal lens element; providing a flow of substantially dry gas in said gap; and tailoring the geometry and velocity of said flow so that, at least in said gap, the flow is non-laminar; and does not excite substantial acoustic vibration in a structure proximal the gap.Type: GrantFiled: March 4, 2014Date of Patent: December 6, 2016Assignee: FEI COMPANYInventors: Tobias Mayer, Rainer Daum, Matthias Geisbauer, Rudolf Johannes Peter Gerardus Schampers, Johannes Antonius Hendricus Wilhelmus Gerardus Persoon
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Patent number: 9201234Abstract: An automated slide scanning system is described. The system comprises an automated focusing unit that is simple and that provides a fine adjustment of a focusing tube without any backlash. The focusing unit comprises a block that is cut or fabricated in a pattern forming a head to support a focusing tube and at least one elongated and rigid arm projecting perpendicularly from the head. One end of the at least one arm is integrally joined to the head. The focusing unit further comprises an elongated, rigid, lever which is substantially parallel and spaced apart from the at least one arm. The lever is pivotally mounted to a hinge and has a first end that is linked to the head of the focusing unit and a second free end. The focusing unit further includes a drive mechanism with a roller coupled to a motor. The roller is eccentric roller and is in constant contact to the lever's second end.Type: GrantFiled: October 20, 2011Date of Patent: December 1, 2015Inventor: William Gelbart
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Patent number: 9180593Abstract: An analyzer is disclosed for optical analysis of a biological specimen. In at least one embodiment, the analyzer includes optics which includes a camera, intermediate optics and front optics. The intermediate optics is movably arranged and the front optics is fixedly arranged. An analyzer for optical analysis of a biological specimen, in at least one embodiment includes a robot for transporting a slide to be analyzed. The robot is controlled by at least three motors to allow movement of the robot in three dimensions. The robot includes a handling device configured to grip the slide.Type: GrantFiled: December 18, 2009Date of Patent: November 10, 2015Assignee: Cella Vision ABInventors: Jan Nilsson, Hans Bengtsson, Ragnar Segersten, Conny Gillström
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Patent number: 9025243Abstract: The present invention can realize stable focus tracking in the AF control of a microscope by calculating an evaluation function based on a light intensity signal received in two regions and adjusting the slope of the evaluation function to be constant.Type: GrantFiled: June 6, 2012Date of Patent: May 5, 2015Assignee: Olympus CorporationInventor: Shinsuke Kaneki
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Publication number: 20140340500Abstract: A surgical microscope 1 comprises an imaging system 2 providing a magnified multidimensional image of an object 3 disposable in a focal plane 4 of the imaging system 2 along at least one optical imaging path 2a, 2b. The imaging system 2 comprises an objective 5 having at least two lens groups 6, 7, through which the at least one optical imaging path 2a, 2b passes consecutively, and which define the focal plane 4 of the imaging system 2. At least one lens group 6 of the objective is moveable along its optical axis relative to the at least one other lens group 7 of the objective. The objective's first lens group 6 located directly adjacent to the focal plane 4 along the at least one optical imaging path 2a, 2b consists of at least three optical lenses 61, 62, 63 and has altogether a negative optical power.Type: ApplicationFiled: May 8, 2014Publication date: November 20, 2014Applicant: Carl Zeiss Meditec AGInventor: Artur HOEGELE
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Patent number: 8873138Abstract: A focusing device for an optical microscope may include a light emitting unit configured to emit laser light having a specific wavelength, a wedge mirror configured to enable the emitted laser light to be incident on a plurality of locations of a surface of a specimen, first and second light receiving units configured to detect an amount of laser light reflected from the surface of the specimen, a spatial filter configured to eliminate out-of-focus light from light beams reflected from the surface of the specimen and to detect an amount of in-focus light, and a control unit configured to generate a control signal used to carry out focus adjustment of the optical microscope using a plurality of light-amount information detected by the first and second light receiving units and the spatial filter.Type: GrantFiled: September 10, 2012Date of Patent: October 28, 2014Assignee: Samsung Electronics Co., Ltd.Inventors: Kwang Soo Kim, Chang Hoon Choi, In Ho Seo, Hyun Jae Lee, Myoung Ki Ahn, Byeong Hwan Jeon, Sung Jin Lee
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Publication number: 20140192405Abstract: A solid state illumination system is provided as a replacement for conventional arc light, metal halide and Xenon white-light sources for applications in life sciences including, microscopy, fluorescence microscopy, and endoscopy. The solid state illumination system generates high quality white light output from LED light sources. In an embodiment, the solid state illumination system is coupled to a microscope using a liquid light guide. The liquid light guide is coupled to a microscope using an adjustable collimator which optimizes the light output for input to the optical train of the microscope.Type: ApplicationFiled: January 9, 2014Publication date: July 10, 2014Applicant: Lumencor, Inc.Inventors: Claudia B. Jaffe, Steven M. Jaffe
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Patent number: 8717672Abstract: Aberrations are sufficiently corrected, and an excellent image is acquired. Provided is a variable-focus optical system including a positive-power front-group optical system, a rear-group optical system having the same power, and an optical-system driving unit configured to relatively change the distance therebetween in the optical axis direction, wherein the front-group optical system consists of a positive-power first-group optical system formed of a joined lens, that is, a lens L1 and a lens L2, a positive-power second-group optical system consisting of a lens L3, and a third-group optical system formed of a lens L4 and a lens L5, and the rear-group optical system consists of a positive-power fourth-group optical system formed of a lens L7 and a lens L6, a fifth-group optical system consisting of a positive-power lens L8, and a positive-power sixth-group optical system formed of a joined lens, that is, a lens L10 and a lens L9.Type: GrantFiled: March 12, 2012Date of Patent: May 6, 2014Assignee: Olympus CorporationInventor: Tadashi Hirata
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Patent number: 8711473Abstract: An optical scanning microscope is presented in which the observation magnification does not significantly change even when the working distance of an objective lens is changed. The optical scanning microscope includes an objective optical system that converts the light from a specimen into a substantially collimated light beam, an imaging optical system that forms an image from the collimated light beam, a pupil projection optical system that substantially collimates the light formed into an image, a lateral scanner that angularly deflects the collimated light beam from the pupil projection optical system to laterally scan the area of the specimen to be observed, and a lens driver that drives the imaging optical system and/or the pupil projection optical system along the optical axis direction. The imaging optical system is disposed such that its front focal point is positioned proximate to the back focal point of the objective optical system.Type: GrantFiled: September 9, 2008Date of Patent: April 29, 2014Assignee: Olympus CorporationInventor: Tadashi Hirata
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Patent number: 8702770Abstract: The invention concerns a scanning device for focusing a beam of rays in defined regions of a defined volume, comprising an input optics wherein the beam of rays penetrates first, having at least one first optical element; a focusing optics for focusing the beam of rays exiting from the input optics; and a deflecting device arranged between the first optical element and the focusing optics, for deflecting the beam of rays after it has passed through the first optical element, based on a position of the focus to be adjusted in lateral direction. In order to adjust the position of the focus of the beam of rays in the direction of the beam of rays, and optical element of the input optics can be displaced relative to the deflecting device.Type: GrantFiled: March 9, 2006Date of Patent: April 22, 2014Assignee: Carl Zeiss Meditec AGInventors: Marco Hanft, Dirk Muehlhoff, Mark Bischoff, Mario Gerlach
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Patent number: 8705171Abstract: A confocal scanning microscope for examining microscopic and macroscopic objects is described. The microscope comprises: a scanning optical system having optical elements imaging the light generated by a laser onto an object to be examined; an objective provided in a working distance of at least 0.4 inches from an object holder; and a zoom optical system that is connected to the scanning optical system such that the light generated by the laser passes first through the scanning optical system, then through the zoom optical system, and is then imaged through the objective onto the object. This microscope achieves that also macroscopic objects can be viewed at a high resolution.Type: GrantFiled: September 24, 2008Date of Patent: April 22, 2014Assignee: Leica Microsystems CMS GmbHInventors: Peter Sendrowski, Claus Kress
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Patent number: 8649088Abstract: A microscope system stores, for each objective, the movement control information including a type flag indicating the type of an objective depending on the presence/absence of a soak or a type of the soak and a save distance for saving the stage or the objective switch unit by a predetermined distance. When a switch direction of objectives is input, and when there is a change in the type of the objective after the switch, the system stops an operation after the stage or the objective switch unit is moved according to the save distance, and recovers the stage or the objective switch unit to an original position after the operation direction input unit inputs an operation direction for the stage and the objective switch unit.Type: GrantFiled: November 5, 2010Date of Patent: February 11, 2014Assignee: Olympus CorporationInventor: Tetsuya Shirota
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Patent number: 8634131Abstract: Spherical aberration is the primary cause of lose of signal while imaging deeper into a sample. Spherical aberration is corrected in the imaging path of a non-descanned detection system (such as a multi-photon microscope). This corrects the illumination spot for artifacts caused by imaging deep into a sample. One exemplary advantage to this instrument is that it allows deeper and brighter imaging.Type: GrantFiled: December 1, 2010Date of Patent: January 21, 2014Assignee: Intelligent Imaging Innovations, Inc.Inventor: Glen Ivan Redford
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Patent number: 8625212Abstract: A system for guiding optical elements, in particular lenses, along an optical axis of a microscope, in particular a stereomicroscope, or of a macroscope, guide system including at least one guide rod which extends parallel to the optical axis and is at least partially made from a magnetizable material, and further including a carrier for the optical elements, the carrier being displaceable along the at least one guide rod and providing magnetic attraction between itself and at least one guide rod; for providing magnetic attraction, including at least one magnetizable wheel adapted to roll along the at least one guide rod while rotating about an axis as the carrier is displaced; the at least one guide rod (312, 314) being made of magnetizable material and/or the magnetizable wheel being at least in part permanently magnetic.Type: GrantFiled: February 11, 2011Date of Patent: January 7, 2014Assignee: Leica Microsystems (Schweiz) AGInventor: Didier Henry
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Publication number: 20130321907Abstract: A new apparatus and method of delivering light to the hack aperture of a High. Numerical Aperture (NA) Microscopy Objective lens for Total Internal Reflectance Microscopy (TIRFM) is provided. The apparatus and method include pumping light generated by a laser through an optical fiber which is optically coupled to the objective lens by a collimating optical element, such as, for example a lens or prism. The apparatus and method also include providing a fiber axial translator which is mechanically adjustable for focusing the laser light optically coupled to the objective lens. The apparatus also includes a mechanical coupler for mechanically coupling the apparatus to the object lens such that the laser light optically coupled to the objective lens can be adjusted to exceed, or not exceed, a critical angle associated with TIRFM illumination.Type: ApplicationFiled: October 13, 2011Publication date: December 5, 2013Inventors: Guy Kennedy, David M. Warshaw
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Publication number: 20130215502Abstract: A focusing apparatus for use with an optical system having a high NA objective lens includes an image forming and capturing mechanism for forming an image in an intermediate image zone and for capturing an image by receiving and refocusing light from a selected focal plane within the intermediate image zone, and a focus adjusting mechanism for adjusting the position of the selected focal plane within the intermediate image zone. The image forming and capturing mechanism includes at least one high NA lens. In use, spherical aberration introduced by the high NA objective lens is reduced.Type: ApplicationFiled: March 18, 2013Publication date: August 22, 2013Applicant: ISIS INNOVATION LIMITEDInventor: ISIS INNOVATION LIMITED
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Publication number: 20130170022Abstract: Exemplary methods, systems and components enable an enhanced direct-viewing optical device to make customized adjustments that accommodate various optical aberrations of a current user. In some instances a real-time adjustment of the transformable optical elements is based on known corrective optical parameters associated with a current user. In some implementations a control module may process currently updated wavefront measurements as a basis for determining appropriate real-time adjustment of the transformable optical elements to produce a specified change in optical wavefront at an exit pupil of the direct-viewing device. Possible transformable optical elements may have refractive and/or reflective and/or diffractive and/or transmissive characteristics that are adjusted based on current performance viewing factors for a given field of view of the direct-viewing device.Type: ApplicationFiled: December 29, 2011Publication date: July 4, 2013Inventors: Kenneth G. Caldeira, Peter L. Hagelstein, Roderick A. Hyde, Edward K.Y. Jung, Jordin T. Kare, Nathan P. Myhrvold, John Brian Pendry, David Schurig, Clarence T. Tegreene, Charles Whitmer, Lowell L. Wood, JR.
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Publication number: 20130075578Abstract: An inverted microscope includes: a microscope main body; a stage that is supported by the microscope main body; and an observation optical system that allows observing a sample placed on the stage from underneath, the microscope main body, in which an optical device can be attached between an objective lens and a tube lens which constitute the observation optical system including a plurality of stage supporting parts that support the stage; and a beam part that connects, in a manner of locating between the tube lens and the objective lens, at least a pair of stage supporting parts at front and back sides together among the plurality of stage supporting parts.Type: ApplicationFiled: November 21, 2012Publication date: March 28, 2013Applicant: OLYMPUS CORPORATIONInventor: OLYMPUS CORPORATION
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Publication number: 20130077158Abstract: An inverted microscope includes: a stage which places a specimen thereon; a light source unit which has a light source irradiating light to the specimen on the stage; an objective lens which focuses at least observation light from the specimen on the stage; a body unit which holds at least the objective lens; a condenser which is provided on an optical axis of the objective lens; a condenser holding unit which holds the condenser; a condenser moving mechanism which movably supports the condenser holding unit and moves the condenser holding unit along the optical axis; a transmission mechanism which transmits power for moving the condenser to the condenser moving mechanism; and an input unit which inputs the power to the transmission mechanism. The input unit is provided above the condenser holding unit.Type: ApplicationFiled: June 27, 2012Publication date: March 28, 2013Applicant: OLYMPUS CORPORATIONInventors: Yusuke MATSUMOTO, Akihiro KITAHARA, Mika FUKUDA
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Publication number: 20130070334Abstract: A focusing device for an optical microscope may include a light emitting unit configured to emit laser light having a specific wavelength, a wedge mirror configured to enable the emitted laser light to be incident on a plurality of locations of a surface of a specimen, first and second light receiving units configured to detect an amount of laser light reflected from the surface of the specimen, a spatial filter configured to eliminate out-of-focus light from light beams reflected from the surface of the specimen and to detect an amount of in-focus light, and a control unit configured to generate a control signal used to carry out focus adjustment of the optical microscope using a plurality of light-amount information detected by the first and second light receiving units and the spatial filter.Type: ApplicationFiled: September 10, 2012Publication date: March 21, 2013Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Kwang Soo KIM, Chang Hoon CHOI, In Ho SEO, Hyun Jae LEE, Myoung Ki AHN, Byeong Hwan JEON, Sung Jin LEE
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Patent number: 8369011Abstract: An observation optical system includes, in order from a sample side, an infinity-corrected objective, a first lens group having a positive power, a second lens group having a positive power, and a tube lens having a positive power. An intermediate image is formed between the first lens group and the second lens group, and at a front side focal position of the second lens group. A space along an optical axis between the objective and the first lens group is configured to be changeable, and a space along an optical axis between the second lens group and the tube lens is configured to be changeable.Type: GrantFiled: July 1, 2010Date of Patent: February 5, 2013Assignee: Olympus CorporationInventors: Kazuhiro Hayashi, Kenji Kawasaki
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Patent number: 8350905Abstract: A microscope system has a VS image generation means for generating a virtual slide image of a specimen which is constructed by mutually connecting a plurality of microscope images with a first photomagnification photographed and acquired whenever an objective lens and the specimen are relatively moved in a direction perpendicular to the optical axis and which represents the entire image of the specimen, an object-of-interest set means setting an object of interest with respect to the entire image of the specimen represented by the VS image, and a three-dimensional VS image generation means for generating a three-dimensional VS image which is constructed by connecting the microscope images at different focal positions in accordance with the same focal position and which is constructed from the microscope images with a second photomagnification higher than the first photomagnification and represents the image of the object of interest.Type: GrantFiled: January 21, 2009Date of Patent: January 8, 2013Assignee: Olympus CorporationInventor: Tatsuki Yamada
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Publication number: 20120320453Abstract: The present invention can realize stable focus tracking in the AF control of a microscope by calculating an evaluation function based on a light intensity signal received in two regions and adjusting the slope of the evaluation function to be constant.Type: ApplicationFiled: June 6, 2012Publication date: December 20, 2012Applicant: OLYMPUS CORPORATIONInventor: Shinsuke KANEKI
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Patent number: 8275226Abstract: A multi-mode optical fiber delivers light from a radiation source to a multi-focal confocal microscope with reasonable efficiency. A core diameter of the multi-mode fiber is selected such that an etendue of light emitted from the fiber is not substantially greater than a total etendue of light passing through a plurality of pinholes in a pinhole array of the multi-focal confocal microscope. The core diameter may be selected taking into account a specific optical geometry of the multi-focal confocal microscope, including pinhole diameter and focal lengths of relevant optical elements. For coherent radiation sources, phase randomization may be included. A multi-mode fiber enables the use of a variety of radiation sources and wavelengths in a multi-focal confocal microscope, since the coupling of the radiation source to the multi-mode fiber is less sensitive to mechanical and temperature influences than coupling the radiation source to a single mode fiber.Type: GrantFiled: December 7, 2009Date of Patent: September 25, 2012Assignee: Spectral Applied Research Ltd.Inventor: Richard Berman
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Publication number: 20120236399Abstract: Aberrations are sufficiently corrected, and an excellent image is acquired. Provided is a variable-focus optical system including a positive-power front-group optical system, a rear-group optical system having the same power, and an optical-system driving unit configured to relatively change the distance therebetween in the optical axis direction, wherein the front-group optical system consists of a positive-power first-group optical system formed of a joined lens, that is, a lens L1 and a lens L2, a positive-power second-group optical system consisting of a lens L3, and a third-group optical system formed of a lens L4 and a lens L5, and the rear-group optical system consists of a positive-power fourth-group optical system formed of a lens L7 and a lens L6, a fifth-group optical system consisting of a positive-power lens L8, and a positive-power sixth-group optical system formed of a joined lens, that is, a lens L10 and a lens L9.Type: ApplicationFiled: March 12, 2012Publication date: September 20, 2012Applicant: OLYMPUS CORPORATIONInventor: Tadashi HIRATA
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Patent number: 8130444Abstract: A telescope imaging system includes a first lens group for receiving a spot light and generating a first refracted beam, a second lens group for receiving the first refracted beam and generating a second refracted beam, a third lens group having a convex lens disposed at a side of the third lens group distant from the spot light for receiving the second refracted beam and generating a parallel beam by an effective focus formed by the first lens group, the second lens group and the third lens group, a first reflective mirror having an opening, receiving the parallel beam and generating a reflected beam, and a second reflective mirror adjacent to the third group lens and reflecting the reflected beam for allowing the reflected beam passing through the opening and focused as an image.Type: GrantFiled: July 2, 2007Date of Patent: March 6, 2012Assignee: National Applied Research LaboratoriesInventors: Shih-Feng Tseng, Yu-Jen Lin, Kuo-Cheng Huang, Wen-Hong Wu, Feng-Chang Hsu
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Patent number: 8040596Abstract: The invention relates to an epi-illumination optical system for microscopes which relies upon a Köhler illumination system using a collective lens array, having simplified adjustment function capable of adjusting the image position of a light source to the back focal position of each microscope objective lens in operable association with microscope objective lens replacement. The invention provides an epi-illumination optical system for microscopes, with an objective lens serving as a condenser lens, which comprises a light source, a collimate lens, and a lens array. The epi-illumination optical system further comprises a projection optical system adapted to project an image of light source formed by collective lens array. The projection optical system comprises a partial optical system movable in an optical axis direction, so that the imaging position for the image array of light source is adjustable to the back focal position of the objective lens.Type: GrantFiled: June 13, 2007Date of Patent: October 18, 2011Assignee: Olympus CorporationInventor: Masayuki Mizusawa
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Patent number: 7940455Abstract: An ophthalmic surgical microscope system (100) includes a surgical microscope (101). The surgical microscope (101) is accommodated on a carrier unit (109) so as to be adjustable in elevation in order to be able to adjust a work distance (124) between the surgical microscope (101) and a patient eye (120). A first drive (112) is provided for adjusting the elevation of the surgical microscope (101). The ophthalmic surgical microscope system (100) includes an ophthalmic ancillary module (114) having an adjustable ophthalmic magnifier lens (116). The work distance (125) between the ophthalmic magnifier lens (116) and the patient eye (120) can be adjusted with a second drive (117). A drive coupling (123) is provided which couples the first drive for adjusting elevation of the surgical microscope (101) to the second drive (117) for adjusting the ophthalmic magnifier lens (116).Type: GrantFiled: September 28, 2007Date of Patent: May 10, 2011Assignee: Carl Zeiss Surgical GmbHInventor: Gerhard Gaida
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Publication number: 20110069381Abstract: An infinity-conjugate lens relay with a moving first lens is used to select a plane of interest from an image volume. This plane can be selected so that the image is corrected for spherical aberration due to non-ideal imaging conditions. This effectively will allow for deeper, corrected imaging for high power microscopes. Using an infinity-conjugate relay, this device has an ideal “bypass” mode for regular imaging without correction. The device also utilizes software that automatically controls the device for correcting live images.Type: ApplicationFiled: September 22, 2010Publication date: March 24, 2011Applicant: INTELLIGENT IMAGING INNOVATIONS, INC.Inventor: Glen Ivan Redford
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Patent number: 7901072Abstract: An ocular device includes a housing, a rotatable ring, a first prism fixed in the rotatable ring, an indexable ring and a second prism fixed in the indexable ring. The housing has a stepped inner profile defining first and second circular tracks in the housing, the tracks being concentric about a rotational axis. The rotatable ring is disposed in the first circular track and is freely rotatable about the rotational axis with respect to the housing. The indexable ring is disposed in the second circular track and is indexable about the rotational axis.Type: GrantFiled: November 13, 2009Date of Patent: March 8, 2011Assignee: Vuzix CorporationInventors: Barry T. Eagan, Paul J. Travers, Theodore K. Ricks, Robert J. Schultz
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Publication number: 20110007389Abstract: An observation optical system includes, in order from a sample side, an infinity-corrected objective, a first lens group having a positive power, a second lens group having a positive power, and a tube lens having a positive power. An intermediate image is formed between the first lens group and the second lens group, and at a front side focal position of the second lens group. A space along an optical axis between the objective and the first lens group is configured to be changeable, and a space along an optical axis between the second lens group and the tube lens is configured to be changeable.Type: ApplicationFiled: July 1, 2010Publication date: January 13, 2011Applicant: Olympus CorporationInventors: Kazuhiro HAYASHI, Kenji KAWASAKI
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Patent number: 7787178Abstract: Without setting an examination site, it is possible to easily position an end face of a narrow-diameter end portion at a suitable position with respect to an examination target, allowing an image of the examination site to be acquired quickly and easily. The invention provides an objective-lens guiding device comprising a support portion secured to an objective lens having a narrow-diameter end portion; and a cylindrical portion for accommodating the narrow-diameter end portion. The support portion supports the cylindrical portion such that a front end of the cylindrical portion is disposed at a location farther toward the front than an end face of the narrow-diameter end portion, and so as to be capable of moving in an optical axis direction.Type: GrantFiled: August 20, 2007Date of Patent: August 31, 2010Assignee: Olympus CorporationInventors: Yasuaki Natori, Masato Fujiwara, Nobuhiko Onda, Tatsuya Okadome, Ikuko Sakai
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Publication number: 20100214653Abstract: The invention relates to a laser scanning microscope with a scanner and a microscope objective, and to a control method for such a microscope. In order to obtain sharp imaging of the sample in a laser scanning microscope, the distance between the microscope objective and the sample is usually varied for adjusting the focus position. However, relative movements between the objective and the sample can be problematic. In view of the costly special objective, internal focusing of the objective is a disadvantageous solution. An improved laser scanning microscope should make it possible to sharply image a sample with standard objectives without relative movement between the microscope objective and sample. According to the invention, a tube lens is provided which is displaceable along the optical axis, and the focus position is adjustable relative to a front optical element of the microscope objective by adjusting the tube lens.Type: ApplicationFiled: August 6, 2008Publication date: August 26, 2010Inventors: Joerg Pacholik, Marco Hanft, Dieter Huhse
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Patent number: 7782539Abstract: An immersion microscope objective includes a system of several optical lenses or lens groups between which air spaces are provided and an adjusting device for adapting the immersion microscope objective to different immersion mediums for correcting imaging errors when utilizing the immersion microscope objective in connection with a cover glass, which closes off a specimen holder, and/or for correcting longitudinal chromatic aberrations. The adjusting device is configured to change two air spaces and especially the air spaces (A1, A2) are linearly changeable.Type: GrantFiled: November 6, 2007Date of Patent: August 24, 2010Assignee: Carl Zeiss MicroImaging GmbHInventors: Renhu Shi, Ingo Fahlbusch, Werner Kleinschmidt
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Patent number: 7729048Abstract: A microscope system includes a stand unit provided with a up/down drive unit for an objective lens, and a base unit provided with a up/down drive unit for a X-Y stage. When the stand unit and the base unit are fixed to each other, a displacement range of the objective lens drive unit along the up/down direction and a displacement range of the stage drive unit along the up/down direction are different from each other.Type: GrantFiled: October 7, 2005Date of Patent: June 1, 2010Assignee: Nikon CorporationInventor: Atsushi Takeuchi
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Patent number: 7706059Abstract: A tube attachment for microscopes which facilitates visual microscope work particularly over extended periods and which can be used universally for different types of microscopes and, at the same time, can be produced economically using simple manufacturing techniques, it is suggested that a tube attachment is constructed as a holder which can be adjusted with respect to height and, optionally, with respect to angle and can be fastened directly to a binocular tube of a microscope. The holder includes two carriers which are displaceable axially relative to one another and which have a forehead rest and a chin support or one carrier with the forehead rest for a user, and devices are provided at the carriers for clamping the adjusting movements of the carriers.Type: GrantFiled: October 12, 2006Date of Patent: April 27, 2010Assignee: Carl Zeiss Microimaging GmbHInventors: Axel Freerk, Cornelia Bendlin, Anke Vogelgsang
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Publication number: 20100091363Abstract: An objective lens to be fitted into a fitting hole of a nosepiece of a microscope includes an imaging lens that is composed of a plurality of lens groups, and a lens barrel that holds the imaging lens. The lens barrel is formed with a fitting portion that is fitted to the fitting hole of the nosepiece and provided at an outer circumference of a tip portion side away by a given distance from the tip portion where a first lens group in the imaging lens is held, and a mount surface that comes into contact with a contact surface of the fitting hole of the nosepiece upon fitting at the fitting portion. The nosepiece is equipped with the objective lens. The inverted microscope is equipped with the nosepiece fitting the objective lens.Type: ApplicationFiled: December 11, 2009Publication date: April 15, 2010Inventor: Takashi KAWAHITO